Search results for SHMT1

Showing 4 results out of 4

×

Species

Types

Compartments

Reaction types

Search properties

Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-71242
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: SHMT1: P34896

Complex (1 results from a total of 1)

Identifier: R-HSA-71243
Species: Homo sapiens
Compartment: cytosol

Reaction (2 results from a total of 2)

Identifier: R-HSA-71249
Species: Homo sapiens
Compartment: cytosol
Cytosolic serine hydroxymethyltransferase tetramer (SHMT1) catalyzes the reaction of 3-Hydroxy-N6,N6,N6-trimethyl-L-lysine (NTMLYS) to form glycine (Gly) and 4-trimethylammoniobutanal (TEABL) in vitro (Hulse et al. 1978). The possibility that an additional enzyme may catalyze this reaction in vivo has not been excluded (Bremer 1983).
Identifier: R-HSA-200735
Species: Homo sapiens
Compartment: cytosol
Cytosolic serine hydroxymethyltransferase catalyzes the reversible reaction of tetrahydrofolate polyglutamate (THF polyglutamate) and serine to form 5,10-methyleneTHF polyglutamate and glycine. The active form of the enzyme is a tetramer (Renwick et al. 1998). In the body, this reaction is a major source of 5,10-methyleneTHF, which in turn is a critical precursor in the synthesis of dTMP.
Cite Us!