Search results for SPHK2

Showing 4 results out of 4

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Species

Types

Compartments

Reaction types

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Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

Identifier: R-HSA-428236
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: SPHK2: Q9NRA0

Set (1 results from a total of 1)

Identifier: R-ALL-9695954
Compartment: cytosol

Reaction (1 results from a total of 1)

Identifier: R-HSA-9695949
Species: Homo sapiens
Compartment: cytosol, endoplasmic reticulum membrane
The cytosolic enzyme sphingosine kinase 2 (SPHK2) catalyzes the phosphorylation of sphingosine (SPG) to sphingosine 1-phosphate (S1P) (Liu et al. 2000). In contrast to pro-survival SPHK1, the BH3-only protein SPHK2 inhibits cell growth and enhances apoptosis (Maceyka et al. 2005).

Complex (1 results from a total of 1)

Identifier: R-HSA-9695910
Species: Homo sapiens
Compartment: cytosol
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