Search results for UCK1

Showing 5 results out of 5

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Species

Types

Compartments

Reaction types

Search properties

Species

Types

Compartments

Reaction types

Search properties

Protein (1 results from a total of 1)

UCK1

Identifier: R-HSA-73503
Species: Homo sapiens
Compartment: cytosol
Primary external reference: UniProt: UCK1: Q9HA47

Interactor (1 results from a total of 1)

UCK1

Identifier: Q9HA47-2
Species: Homo sapiens
Primary external reference: UniProt: Q9HA47-2

Complex (1 results from a total of 1)

UCK1 tetramer

Identifier: R-HSA-73504
Species: Homo sapiens
Compartment: cytosol

Reaction (2 results from a total of 2)

cytidine or uridine + ATP => CMP or UMP + ADP [UCK1]

Identifier: R-HSA-73599
Species: Homo sapiens
Compartment: cytosol
Cytosolic uridine-cytidine kinase 1 (UCK1) catalyzes the reactions of cytidine or uridine with ATP to form CMP or UMP and ADP (Greenberg et al. 1977; Van Rompay et al. 2001). Unpublished crystallographic data show the enzyme to be a tetramer (PDB - 2JEO).

UCKL1 phosphorylates urindine, cytidine

Identifier: R-HSA-8954327
Species: Homo sapiens
Compartment: cytosol
Based on sequence similarity, cytosolic uridine-cytidine kinase-like 1 (UCKL1 aka F538) is thought to function as a novel human uridine kinase/uracil phosphoribosyltransferase (Kashuba et al. 2002). The two human uridine kinases 1 and 2 (UCK1 and UCK2) characterised to date phosphorylate uridine/cytidine to uridine monophosphate (UMP)/cytidine monophosphate (CMP) using ATP as a phosphate donor (Greenberg et al. 1977, Van Rompay et al. 2001).
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