Search results for UGCG

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Species

Types

Compartments

Reaction types

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Protein (1 results from a total of 1)

UGCG

Identifier: R-HSA-1631585
Species: Homo sapiens
Compartment: Golgi membrane
Primary external reference: UniProt: UGCG: Q16739

Reaction (1 results from a total of 1)

UGCG transfers glucose to ceramide

Identifier: R-HSA-1638104
Species: Homo sapiens
Compartment: Golgi membrane, Golgi lumen
Ceramide glucosyltransferase (UGCG, CGT, GCS) catalyzes the first glycosylation step in glycosphingolipid biosynthesis by transferring glucose to ceramide (Ichikawa et al. 1996). UGCG is localized on the cytosolic part of the cis-Golgi membrane. The cytosolic PLEKHA8 (FAPP2) will transport the product GlcCer to the plasma membrane. GlcCer is also transported to the inside of the Golgi membrane by MDR1 ("flipping"; Fabiana de Rosa et al., 2004; Eckford & Sharom, 2005; reviewed by Liu & Li, 2013).
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