Search results for VAC14

Showing 14 results out of 14

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Protein (3 results from a total of 3)

Identifier: R-HSA-1806235
Species: Homo sapiens
Compartment: Golgi membrane
Primary external reference: UniProt: VAC14: Q08AM6
Identifier: R-HSA-1806207
Species: Homo sapiens
Compartment: early endosome membrane
Primary external reference: UniProt: Q08AM6
Identifier: R-HSA-1806219
Species: Homo sapiens
Compartment: late endosome membrane
Primary external reference: UniProt: Q08AM6

Reaction (11 results from a total of 11)

Identifier: R-HSA-1675921
Species: Homo sapiens
Compartment: Golgi membrane, cytosol
At the Golgi membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger (Sbrissa et al. 2002). The PIKFYVE kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999, McEwen et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007). VAC14 acts as a scaffolding protein via its C-terminal domain (Sbrissa et al. 2008).
Identifier: R-NUL-1675982
Species: Mus musculus, Homo sapiens
Compartment: Golgi membrane, cytosol
At the Golgi membrane, the PAS complex, consisting of mouse FYVE finger-containing phosphoinositide kinase (Pikfyve), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via Pikfyve's FYVE finger (Sbrissa et al. 2002). The Pikfyve kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999, McEwen et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007). VAC14 acts as a scaffolding protein via its C-terminal domain (Sbrissa et al. 2008).
Identifier: R-HSA-1676005
Species: Homo sapiens
Compartment: Golgi membrane, cytosol
At the Golgi membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger. The FIG4 phosphatase component dephosphorylates phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) to phosphatidylinositol 3-phosphate (PI3P) (Sbrissa et al. 2007, Sbrissa et al. 2008).
Identifier: R-HSA-1676168
Species: Homo sapiens
Compartment: early endosome membrane, cytosol
At the early endosome membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger (Sbrissa et al. 2002, Cao et al. 2007). The PIKFYVE kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007).
Identifier: R-NUL-1675886
Species: Mus musculus, Homo sapiens
Compartment: early endosome membrane, cytosol
At the early endosome membrane, the PAS complex, consisting of mouse FYVE finger-containing phosphoinositide kinase (Pikfyve), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via Pikfyve's FYVE finger (Sbrissa et al. 2002, Cao et al. 2007). The Pikfyve kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007).
Identifier: R-HSA-1676174
Species: Homo sapiens
Compartment: early endosome membrane, cytosol
At the early endosome membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger. The FIG4 phosphatase component dephosphorylates phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) to phosphatidylinositol 3-phosphate (PI3P) (Sbrissa et al. 2007, Sbrissa et al. 2008).
Identifier: R-HSA-1675910
Species: Homo sapiens
Compartment: late endosome membrane, cytosol
At the late endosome membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger (Sbrissa et al. 2002, Cao et al. 2007). The PIKFYVE kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007).
Identifier: R-NUL-1675925
Species: Mus musculus, Homo sapiens
Compartment: late endosome membrane, cytosol
At the late endosome membrane, the PAS complex, consisting of mouse FYVE finger-containing phosphoinositide kinase (Pikfyve), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via Pikfyve's FYVE finger (Sbrissa et al. 2002, Cao et al. 2007). The Pikfyve kinase component phosphorylates phosphatidylinositol 3-phosphate (PI3P) to phosphatidylinositol 3,5-bisphosphate PI(3,5)P2 (Sbrissa et al. 1999). The PAS complex is present in the cytosol and is recruited to the membrane (Sbrissa et al. 2007).
Identifier: R-HSA-1676020
Species: Homo sapiens
Compartment: late endosome membrane, cytosol
At the late endosome membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger. The FIG4 phosphatase component dephosphorylates phosphatidylinositol 3,5-bisphosphate (PI(3,5)P2) to phosphatidylinositol 3-phosphate (PI3P) (Sbrissa et al. 2007, Sbrissa et al. 2008).
Identifier: R-HSA-1675866
Species: Homo sapiens
Compartment: late endosome membrane, cytosol
At the late endosome membrane, the PAS complex, consisting of FYVE finger-containing phosphoinositide kinase (PIKFYVE), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via PIKFYVE's FYVE finger. The PIKFYVE kinase component phosphorylates phosphatidylinositol (PI) to phosphatidylinositol 5-phosphate (PI5P) (Sbrissa et al. 1999, Sbrissa et al. 2002). The PAS complex is present in the cytosol and is recruited to the membrane.
Identifier: R-NUL-1676051
Species: Mus musculus, Homo sapiens
Compartment: late endosome membrane, cytosol
At the late endosome membrane, the PAS complex, consisting of mouse FYVE finger-containing phosphoinositide kinase (Pikfyve), yeast VAC14 homologue (VAC14), and polyphosphoinositide phosphatase aka SAC3 (FIG4), binds to the membrane via Pikfyve's FYVE finger. The Pikfyve kinase component phosphorylates phosphatidylinositol (PI) to phosphatidylinositol 5-phosphate (PI5P) (Sbrissa et al. 1999, Sbrissa et al. 2002). The PAS complex is present in the cytosol and is recruited to the membrane.
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