The B30.2 cytoplasmic domain (PRY/SPRY domain) of Butyrophilin 1A1 (BTN1A1) binds the enzyme xanthine oxidoreductase (XDH). This interaction provides scaffolding function, stabilizes the milk fat globule membrane (MFGM), and aids in milk fat globule secretion (Jeong et al. 2009).
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reaction of hypoxanthine with H2O and oxygen to form xanthine and H2O2. The active form of the enzyme is a dimer (Saksela and Raivio 1996; Yamaguchi et al. 2007).
Cytosolic xanthine dehydrogenase (XDH) catalyzes the reaction of xanthine with H2O to form urate and H2O2. The active form of the enzyme is a dimer (Saksela and Raivio 1996; Yamaguchi et al. 2007).