Reactome: A Curated Pathway Database
2-oxoglutarate O2
2-oxoglutarate O2
Description: Alpha-Ketoglutaric acid is one of two ketone derivatives of glutaric acid

Curator: Bruce May
2’-0-ACETYL- ADP-RIBOSE
2’-0-ACETYL- ADP-RIBOSE
Description: A nucleotide-sugar having ADP as the nucleotide fragment and 2-O-acetyl-D-ribofuranos-5-yl as the sugar component

Curator: Bruce May
2’-o-methylN
2’-o-methylN
Description: 2’-o-methylN

Curator: Bruce May
6A
6A
Description: 6-dimethyladenosine

Curator: Bruce May
Ac-CoA
Ac-CoA
Description: Acetyl coenzyme A or acetyl-CoA is a molecule that participates in many biochemical reactions in protein, carbohydrate and lipid metabolism

Curator: Bruce May
Ac
Ac
Description: The acetyl group contains a methyl group single-bonded to a carbonyl

ac4C
ac4C
Description: N4-acetylcytidine

Curator: Bruce May
AdoHcy
AdoHcy
Description: S-adenosylhomocysteine

Curator: Bruce May
AdoMet
AdoMet
Description: S-adenosylmethionine

Curator: Bruce May
ADP
ADP
Description: Adenosine diphosphate

Curator: Steve Jupe
ADR
ADR
Description: Adrenaline

Curator: Steve Jupe
alpha-TOH
alpha-TOH
Description: alpha-Tocopherol

Curator: Bijay Jassal
Am
Am
Description: 2'-o-methyladenosine

Curator: Bruce May
AMINES
AMINES
Description: Compounds and functional groups that contain a basic nitrogen atom with a lone pair

Curator: Bijay Jassal
AMINO ACIDS
AMINO ACIDS
Description: Amino acids are organic compounds containing amine (-NH2) and carboxyl (-COOH) functional groups, along with a side chain (R group) specific to each amino acid

Curator: Bijay Jassal
AREs
AREs
Description: Adenylate-uridylate-rich elements

Curator: Bruce May
ATP
ATP
Description: Adenosine triphosphate

Curator: Steve Jupe
BILE SALTS
BILE SALTS
Description: The salt forms of bile acids

Curator: Bijay Jassal
CA2+
CA2+
Description: Calcium

Curator: Steve Jupe
Cd2+
Cd2+
Description: Cadmium

Curator: Bruce May
CH2OH
CH2OH
Description: The hydroxymethyl group consists of a methylene bridge bonded to a hydroxy group

Curator: Bruce May
CH3
CH3
Description: A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms

Curator: Bruce May
Cl-
Cl-
Description: Chlorine

Curator: Steve Jupe
Cm
Cm
Description: 2'-o-methylcyanosine

Curator: Bruce May
CO2
CO2
Description: Carbon dioxide

Curator: Steve Jupe
CoA-SH
CoA-SH
Description: Coenzyme A is a coenzyme, notable for its role in the synthesis and oxidation of fatty acids, and the oxidation of pyruvate in the citric acid cycle

Curator: Bruce May
CORTISOL
CORTISOL
Description: Cortisol is a steroid hormone, in the glucocorticoid class of hormones

Curator: Bijay Jassal
D
D
Description: Dihydrouridine

Curator: Bruce May
DAG
DAG
Description: Diglyceride or diacylglycerol

Curator: Steve Jupe
DOLP
DOLP
Description: Dolichol phosphate

Curator: Bruce May
fatty acid
fatty acid
Description: A fatty acid is a carboxylic acid with a long aliphatic chain

Curator: Bruce May
Fe2+
Fe2+
Description: Iron

Curator: Steve Jupe
Gal
Gal
Description: Galactose

Curator: Bruce May
GalNAc
GalNAc
Description: N-Acetylgalactosamine is an amino sugar derivative of galactose

Curator: Bruce May
GDP
GDP
Description: Guanosine diphosphate

Curator: Steve Jupe
GGPP
GGPP
Description: Geranylgeranyl pyrophosphate

Curator: Bruce May
GlcNAc
GlcNAc
Description: N-acetylglucosamine

Curator: Bruce May
GLN
GLN
Description: Glutamine

Curator: Steve Jupe
GLU
GLU
Description: Glutamic acid

Curator: Steve Jupe
GLYCEROL
GLYCEROL
Description: A simple polyol compound

Curator: Bruce May
Gm
Gm
Description: 2'-o-methylguanosine

Curator: Bruce May
GPI
GPI
Description: Glycosyl-phosphatidylinositol

Curator: Bruce May
GTP
GTP
Description: Guanosine-5'-triphosphate

Curator: Steve Jupe
H+
H+
Description: Hydrogen

Curator: Steve Jupe
H2O
H2O
Description: Water

Curator: Steve Jupe
H2O2
H2O2
Description: Hydrogen peroxide

Curator: Steve Jupe
HCO3
HCO3
Description: Bicarbonate

Curator: Steve Jupe
HEME
HEME
Description: Heme is a cofactor consisting of an Fe2+ ion contained in the centre of a heterocyclic macrocycle organic compound called a porphyrin, made up of four pyrrolic groups joined together by methine bridges

Curator: Steve Jupe
HEXOSES
HEXOSES
Description: A hexose is a monosaccharide with six carbon atoms

Curator: Bijay Jassal
HMG-CoA
HMG-CoA
Description: 3-hydroxy-3-methylglutaryl-coenzyme A

Curator: Bijay Jassal
HOCl
HOCl
Description: Hypochlorous acid

Curator: Steve Jupe
I
I
Description: Inosine is a nucleoside that is formed when hypoxanthine is attached to a ribose ring

Curator: Bruce May
i6A
i6A
Description: 6-isopentenyladenosine

Curator: Bruce May
IFN-alpha
IFN-alpha
Description: Interferon alpha

Curator: Corina Duenas
IFN-beta
IFN-beta
Description: Interferon beta-1a

Curator: Corina Duenas
IFN-gamma
IFN-gamma
Description: Interferon gamma is a dimerized soluble cytokine that is the only member of the type II class of interferons

Curator: Steve Jupe
INORGANIC CATIONS
INORGANIC CATIONS
Description: Ion with fewer electrons than protons, giving it a positive charge

Curator: Bijay Jassal
IP3
IP3
Description: Inositol trisphosphate receptor

Curator: Steve Jupe
K+
K+
Description: Potassium

Curator: Steve Jupe
L-GLU
L-GLU
Description: L-glutamine

Curator: Bruce May
m1A
m1A
Description: 1-methyladenosine

Curator: Bruce May
m1acp3Y
m1acp3Y
Description: N1-methyl-N3-amino-carboxypropylpseudouridine

Curator: Bruce May
m1G
m1G
Description: 1-methylguanosine

Curator: Bruce May
m1Gm
m1Gm
Description: 2 2 dimethylguanosine

Curator: Bruce May
m1I
m1I
Description: 1-methylinosine

Curator: Bruce May
m1Y
m1Y
Description: N1-methylpseudouridine

Curator: Bruce May
m2G
m2G
Description: 2-methylguanosine

Curator: Bruce May
m5C
m5C
Description: 5-methylcytidine

Curator: Bruce May
m7G
m7G
Description: 7-methylguanosine

Curator: Bruce May
Man
Man
Description: Mannose

Curator: Bruce May
mcm5U
mcm5U
Description: 5-methylcarbamoylmethyluridine

Curator: Bruce May
Me
Me
Description: A methyl group is an alkyl derived from methane, containing one carbon atom bonded to three hydrogen atoms

METALS
METALS
Description: Metals

Curator: Bijay Jassal
methionine
methionine
Description: Methionine is an essential amino acid in humans

Curator: Bruce May
methionine sulfoxide
methionine sulfoxide
Description: Methionine sulfoxide is an amino acid that occurs naturally although it is formed post-translationally

Curator: Bruce May
MK4
MK4
Description: Menatetrenone is a vitamin K compound

Curator: Bijay Jassal
MK4 epoxide
MK4 epoxide
Description: Highly reactive menatetrenone

Curator: Bijay Jassal
modified nucleotide
modified nucleotide
Description: Representation of a modified nucleotide

Curator: Bruce May
ms2i6A
ms2i6A
Description: 2-methylthio-N6_isopentenyladenosine

Curator: Bruce May
ms2m6A
ms2m6A
Description: 2-metylthio-N6-threonylcarbamoyladenosine

Curator: Bruce May
Na+
Na+
Description: Sodium

Curator: Steve Jupe
NAD+
NAD+
Description: The oxidised form of nicotinamide adenine dinucleotide found in all living cells. In metabolism, NAD+ is involved in redox reactions, carrying electrons from one reaction to another

Curator: Bruce May
NAM
NAM
Description: Nicotinamide

Curator: Bruce May
NH4+
NH4+
Description: Ammonium

Curator: Steve Jupe
NMPs
NMPs
Description: Nucleotide monophosphates

Curator: Bijay Jassal
NO
NO
Description: Nitric oxide

Curator: Steve Jupe
NUCLEOSIDES
NUCLEOSIDES
Description: Nucleosides are glycosylamines that can be thought of as nucleotides without a phosphate group

Curator: Bijay Jassal
NUCLEOTIDES
NUCLEOTIDES
Description: Nucleotides are organic molecules that serve as the monomer units for forming the nucleic acid polymers DNA and RNA, both of which are essential biomolecules in all life-forms on Earth

Curator: Bijay Jassal
O-2
O-2
Description: Oxygen

Curator: Steve Jupe
O2
O2
Description: Oxygen

Curator: Steve Jupe
OCTANOIC ACID
OCTANOIC ACID
Description: Octanoic Acid is a saturated medium-chain fatty acid with an 8-carbon backbone

Curator: Bruce May
ORGANIC ACIDS
ORGANIC ACIDS
Description: An organic acid is an organic compound with acidic properties

Curator: Bijay Jassal
ORGANIC ANIONS
ORGANIC ANIONS
Description: Organic anions are chemically heterogeneous substances possessing a carbon backbone and a net negative charge

Curator: Bijay Jassal
PEPTIDES
PEPTIDES
Description: Short chains of amino acid monomers linked by peptide (amide) bonds

Curator: Bijay Jassal
PGI2
PGI2
Description: Prostacyclin is a prostaglandin member of the eicosanoid family of lipid molecules

Curator: Steve Jupe
phosphorylate
phosphorylate
Description: A phosphoryl group

Curator: Steve Jupe
PHYLLOQUINOL
PHYLLOQUINOL
Description: 2-methyl-3-phytyl-1,4-naphthoquinol vitamin K1

Curator: Bruce May
PHYLLOQUINOL epoxide
PHYLLOQUINOL epoxide
Description: Vitamin K1 epoxide

Curator: Bruce May
PIP2
PIP2
Description: Phosphatidylinositol 4,5-bisphosphate

Curator: Steve Jupe
polyadenylate
polyadenylate
Description: Representation of a chain of Adenosine monophosphates

Curator: Bruce May
pp(pN)
pp(pN)
Description: 5' triphospate end

Curator: Bruce May
PPi
PPi
Description: Pyrophosphate

Curator: Bruce May
pyrophosphate
pyrophosphate
Description: Phosphorus oxyanion

Curator: Bruce May
QtRNA
QtRNA
Description: Queuosine is a modified nucleoside that is present in certain tRNAs in bacteria and eukaryotes

Curator: Bruce May
RA
RA
Description: Retinoic acid is a metabolite of vitamin A or retinol

Curator: Bruce May
retinyl ester
retinyl ester
Description: All-trans-retinyl ester 13-cis isomerohydrolase

Curator: Bijay Jassal
ROH
ROH
Description: Alcohol

Curator: Bijay Jassal
ROS
ROS
Description: Reactive oxygen species (ROS) are chemically reactive chemical species containing oxygen. Examples include peroxides, superoxide, hydroxyl radical, and singlet oxygen

s2U
s2U
Description: 2-thiouridine

Curator: Bruce May
sialic acid
sialic acid
Description: Sialic acid is a generic term for the N- or O-substituted derivatives of neuraminic acid, a monosaccharide with a nine-carbon backbone

Curator: Bruce May
succinate CO2
succinate CO2
Description: Succinate CO2

Curator: Bruce May
T
T
Description: Pyrimidine deoxynucleoside

Curator: Bruce May
t6A
t6A
Description: N6-threonylcarbamoyladenosine

Curator: Bruce May
tm5s2U
tm5s2U
Description: 5-taurinomethyl-2-thiouridine

Curator: Bruce May
tm5U
tm5U
Description: 5-taurinomethyluridine

Curator: Bruce May
TP53 tetramer
TP53 tetramer
Description: Cellular tumor antigen p53

TTPA
TTPA
Description: Alpha-tocopherol transfer protein is a protein that in humans is encoded by the TTPA gene

Curator: Bijay Jassal
UDP
UDP
Description: Uridine diphosphate is a nucleotide diphosphate

Curator: Bruce May
Um
Um
Description: 2'-o-methyluridine

Curator: Bruce May
VITAMINS
VITAMINS
Description: A vitamin is an organic compound and a vital nutrient that an organism requires in limited amounts

Curator: Bijay Jassal
vitK3
vitK3
Description: Menadione

Curator: Bijay Jassal
Y
Y
Description: An isomer of the nucleoside uridine in which the uracil is attached via a carbon-carbon instead of a nitrogen-carbon glycosidic bond

Curator: Bruce May
yW
yW
Description: Heavily modified nucleoside of phenylalanine transfer RNA that stabilizes interactions between the codons and anti-codons during protein synthesis

Curator: Bruce May
Zn2+
Zn2+
Description: Zinc


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