Toggle navigation
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
Tissue Distribution
Analysis Service
Content Service
ReactomeFIViz
Advanced Data Search
Site Search
Community
Contribute Pathway Knowledge
Icon Library
Outreach
Events
Publications
Partners
Contributors
Resources Guide
Download
Search ...
Go!
Ca2+ [endoplasmic reticulum lumen]
Stable Identifier
R-ALL-111875
Type
Chemical Compound [SimpleEntity]
Compartment
endoplasmic reticulum lumen
Synonyms
Calcium, calcium(2+)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Bos taurus)
STIM1 oligomerizes (Bos taurus)
STIM1:Calcium [endoplasmic reticulum membrane] (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Sphingolipid metabolism (Bos taurus)
Glycosphingolipid metabolism (Bos taurus)
Glycosphingolipid catabolism (Bos taurus)
M6PR transports activated ARSA to the lysosome (Bos taurus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Bos taurus)
active ARS [endoplasmic reticulum lumen] (Bos taurus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)
The activation of arylsulfatases (Bos taurus)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Bos taurus)
active ARS [endoplasmic reticulum lumen] (Bos taurus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Ion homeostasis (Bos taurus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Ion transport by P-type ATPases (Bos taurus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Signaling by the B Cell Receptor (BCR) (Caenorhabditis elegans)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Caenorhabditis elegans)
STIM1 oligomerizes (Caenorhabditis elegans)
STIM1:Calcium [endoplasmic reticulum membrane] (Caenorhabditis elegans)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Ion homeostasis (Caenorhabditis elegans)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Caenorhabditis elegans)
Sensory perception of taste (Caenorhabditis elegans)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Caenorhabditis elegans)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Caenorhabditis elegans)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Ion transport by P-type ATPases (Caenorhabditis elegans)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Canis familiaris)
STIM1 oligomerizes (Canis familiaris)
STIM1:Calcium [endoplasmic reticulum membrane] (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Sphingolipid metabolism (Canis familiaris)
Glycosphingolipid metabolism (Canis familiaris)
Glycosphingolipid catabolism (Canis familiaris)
M6PR transports activated ARSA to the lysosome (Canis familiaris)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Canis familiaris)
active ARS [endoplasmic reticulum lumen] (Canis familiaris)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
The activation of arylsulfatases (Canis familiaris)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Canis familiaris)
active ARS [endoplasmic reticulum lumen] (Canis familiaris)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Ion homeostasis (Canis familiaris)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Ion transport by P-type ATPases (Canis familiaris)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Danio rerio)
Cardiac conduction (Danio rerio)
Ion homeostasis (Danio rerio)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Danio rerio)
Ion channel transport (Danio rerio)
Ion transport by P-type ATPases (Danio rerio)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Dictyostelium discoideum)
Sensory perception of taste (Dictyostelium discoideum)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Dictyostelium discoideum)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Dictyostelium discoideum)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Drosophila melanogaster)
STIM1 oligomerizes (Drosophila melanogaster)
STIM1:Calcium [endoplasmic reticulum membrane] (Drosophila melanogaster)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Drosophila melanogaster)
Sensory perception of taste (Drosophila melanogaster)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Drosophila melanogaster)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Drosophila melanogaster)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Ion transport by P-type ATPases (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Gallus gallus)
STIM1 oligomerizes (Gallus gallus)
STIM1:Calcium [endoplasmic reticulum membrane] (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Sphingolipid metabolism (Gallus gallus)
Glycosphingolipid metabolism (Gallus gallus)
Glycosphingolipid catabolism (Gallus gallus)
M6PR transports activated ARSA to the lysosome (Gallus gallus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Gallus gallus)
active ARS [endoplasmic reticulum lumen] (Gallus gallus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)
The activation of arylsulfatases (Gallus gallus)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Gallus gallus)
active ARS [endoplasmic reticulum lumen] (Gallus gallus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Ion homeostasis (Gallus gallus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Gallus gallus)
Ion channel transport (Gallus gallus)
Ion transport by P-type ATPases (Gallus gallus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Gallus gallus)
Ca2+ [endoplasmic reticulum lumen]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
FCGR3A-mediated IL10 synthesis (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
STIM1 oligomerizes (Homo sapiens)
STIM1:Calcium [endoplasmic reticulum membrane] (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
CLEC7A (Dectin-1) induces NFAT activation (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated Ca+2 mobilization (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
Role of phospholipids in phagocytosis (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of lipids (Homo sapiens)
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Glycosphingolipid catabolism (Homo sapiens)
M6PR transports activated ARSA to the lysosome (Homo sapiens)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Homo sapiens)
active ARS [endoplasmic reticulum lumen] (Homo sapiens)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
The activation of arylsulfatases (Homo sapiens)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Homo sapiens)
active ARS [endoplasmic reticulum lumen] (Homo sapiens)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated cell proliferation (Homo sapiens)
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Mus musculus)
STIM1 oligomerizes (Mus musculus)
STIM1:Calcium [endoplasmic reticulum membrane] (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Sphingolipid metabolism (Mus musculus)
Glycosphingolipid metabolism (Mus musculus)
Glycosphingolipid catabolism (Mus musculus)
M6PR transports activated ARSA to the lysosome (Mus musculus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Mus musculus)
active ARS [endoplasmic reticulum lumen] (Mus musculus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
The activation of arylsulfatases (Mus musculus)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Mus musculus)
active ARS [endoplasmic reticulum lumen] (Mus musculus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Mus musculus)
Cardiac conduction (Mus musculus)
Ion homeostasis (Mus musculus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Mus musculus)
Ion channel transport (Mus musculus)
Ion transport by P-type ATPases (Mus musculus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Plasmodium falciparum)
Cardiac conduction (Plasmodium falciparum)
Ion homeostasis (Plasmodium falciparum)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Plasmodium falciparum)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Plasmodium falciparum)
Ion channel transport (Plasmodium falciparum)
Ion transport by P-type ATPases (Plasmodium falciparum)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Plasmodium falciparum)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Rattus norvegicus)
STIM1 oligomerizes (Rattus norvegicus)
STIM1:Calcium [endoplasmic reticulum membrane] (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Sphingolipid metabolism (Rattus norvegicus)
Glycosphingolipid metabolism (Rattus norvegicus)
Glycosphingolipid catabolism (Rattus norvegicus)
M6PR transports activated ARSA to the lysosome (Rattus norvegicus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Rattus norvegicus)
active ARS [endoplasmic reticulum lumen] (Rattus norvegicus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
The activation of arylsulfatases (Rattus norvegicus)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Rattus norvegicus)
active ARS [endoplasmic reticulum lumen] (Rattus norvegicus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Rattus norvegicus)
Cardiac conduction (Rattus norvegicus)
Ion homeostasis (Rattus norvegicus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Ion transport by P-type ATPases (Rattus norvegicus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Schizosaccharomyces pombe)
Metabolism of lipids (Schizosaccharomyces pombe)
Sphingolipid metabolism (Schizosaccharomyces pombe)
Glycosphingolipid metabolism (Schizosaccharomyces pombe)
Glycosphingolipid catabolism (Schizosaccharomyces pombe)
M6PR transports activated ARSA to the lysosome (Schizosaccharomyces pombe)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Schizosaccharomyces pombe)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Signaling by the B Cell Receptor (BCR) (Sus scrofa)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Sus scrofa)
STIM1 oligomerizes (Sus scrofa)
STIM1:Calcium [endoplasmic reticulum membrane] (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Sphingolipid metabolism (Sus scrofa)
Glycosphingolipid metabolism (Sus scrofa)
Glycosphingolipid catabolism (Sus scrofa)
M6PR transports activated ARSA to the lysosome (Sus scrofa)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Sus scrofa)
active ARS [endoplasmic reticulum lumen] (Sus scrofa)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Sus scrofa)
The activation of arylsulfatases (Sus scrofa)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Sus scrofa)
active ARS [endoplasmic reticulum lumen] (Sus scrofa)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Sus scrofa)
Cardiac conduction (Sus scrofa)
Ion homeostasis (Sus scrofa)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Sus scrofa)
Ion channel transport (Sus scrofa)
Ion transport by P-type ATPases (Sus scrofa)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Sus scrofa)
Ca2+ [endoplasmic reticulum lumen]
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Signaling by the B Cell Receptor (BCR) (Xenopus tropicalis)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Xenopus tropicalis)
STIM1 oligomerizes (Xenopus tropicalis)
STIM1:Calcium [endoplasmic reticulum membrane] (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Sphingolipid metabolism (Xenopus tropicalis)
Glycosphingolipid metabolism (Xenopus tropicalis)
Glycosphingolipid catabolism (Xenopus tropicalis)
M6PR transports activated ARSA to the lysosome (Xenopus tropicalis)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Xenopus tropicalis)
active ARS [endoplasmic reticulum lumen] (Xenopus tropicalis)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Xenopus tropicalis)
The activation of arylsulfatases (Xenopus tropicalis)
SUMF1 mediates the oxidation of cysteine to formylglycine, producing active arylsulfatases (Xenopus tropicalis)
active ARS [endoplasmic reticulum lumen] (Xenopus tropicalis)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
Muscle contraction (Xenopus tropicalis)
Cardiac conduction (Xenopus tropicalis)
Ion homeostasis (Xenopus tropicalis)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
Sensory Perception (Xenopus tropicalis)
Sensory perception of taste (Xenopus tropicalis)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Xenopus tropicalis)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
Transport of small molecules (Xenopus tropicalis)
Ion channel transport (Xenopus tropicalis)
Ion transport by P-type ATPases (Xenopus tropicalis)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Xenopus tropicalis)
Ca2+ [endoplasmic reticulum lumen]
External Reference Information
External Reference
calcium(2+) [ChEBI:29108]
Participates
as a component of
convertase (Calcium dependant) [endoplasmic reticulum lumen] (Mus musculus)
STIM1:Calcium [endoplasmic reticulum membrane] (Homo sapiens)
STIM1:Calcium [endoplasmic reticulum membrane] (Sus scrofa)
STIM1:Calcium [endoplasmic reticulum membrane] (Mus musculus)
STIM1:Calcium [endoplasmic reticulum membrane] (Bos taurus)
STIM1:Calcium [endoplasmic reticulum membrane] (Canis familiaris)
STIM1:Calcium [endoplasmic reticulum membrane] (Gallus gallus)
STIM1:Calcium [endoplasmic reticulum membrane] (Drosophila melanogaster)
STIM1:Calcium [endoplasmic reticulum membrane] (Caenorhabditis elegans)
STIM1:Calcium [endoplasmic reticulum membrane] (Xenopus tropicalis)
STIM1:Calcium [endoplasmic reticulum membrane] (Rattus norvegicus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Mus musculus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Homo sapiens)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Rattus norvegicus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Schizosaccharomyces pombe)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Canis familiaris)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Bos taurus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Sus scrofa)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Gallus gallus)
active ARSA:Ca2+ [endoplasmic reticulum lumen] (Xenopus tropicalis)
as an input of
IP3R:I(1,4,5)P3 tetramer transports Ca2+ from ER lumen to cytosol (Homo sapiens)
Calcium release from intracellular stores by IP3 receptor activation (Rattus norvegicus)
Decreasing cGMP concentration promotes intracellular Ca2+ release in response to WNT (Homo sapiens)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Homo sapiens)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Mus musculus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Rattus norvegicus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Canis familiaris)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Bos taurus)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Sus scrofa)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Xenopus tropicalis)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Drosophila melanogaster)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Caenorhabditis elegans)
ITPR3 transports Ca2+ from the endoplasmic reticulum to the cytosol (Dictyostelium discoideum)
as an output of
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Homo sapiens)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Mus musculus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Rattus norvegicus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Canis familiaris)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Bos taurus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Sus scrofa)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Danio rerio)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Xenopus tropicalis)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Gallus gallus)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Drosophila melanogaster)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Caenorhabditis elegans)
ATP2A1-3 transport Ca2+ from cytosol to ER lumen (Plasmodium falciparum)
Other forms of this molecule
Ca2+ [platelet dense granule lumen]
Ca2+ [endosome membrane]
Ca2+ [sarcoplasmic reticulum lumen]
Ca2+ [mitochondrial intermembrane space]
Ca2+ [lysosomal lumen]
Ca2+ [endocytic vesicle lumen]
Ca2+ [endoplasmic reticulum-Golgi intermediate compartment]
Ca2+ [Golgi lumen]
Ca2+ [platelet dense tubular network lumen]
Ca2+ [platelet dense tubular network membrane]
Ca2+ [plasma membrane]
Ca2+ [secretory granule lumen]
Ca2+ [nuclear envelope]
Ca2+ [nucleoplasm]
Ca2+ [mitochondrial matrix]
Ca2+ [mitochondrial inner membrane]
Ca2+ [endoplasmic reticulum membrane]
Ca2+ [cytosol]
Ca2+ [extracellular region]
Cross References
COMPOUND
C00076
PubChem Substance
8145461
HMDB Metabolite
HMDB0000464
© 2025
Reactome
Cite Us!
Cite Us!
Cite Us!
Warning!
Unable to extract citation. Please try again later.
Download As:
BibTeX
RIS
Text