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GMP [extracellular region]
Stable Identifier
R-ALL-113579
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
guanosine 5'-monophosphate, Guanosine 5'-phosphate, Guanosine monophosphate, Guanylic acid, guanosine 5'-monophosphate(2-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide catabolism (Bos taurus)
Phosphate bond hydrolysis by NTPDase proteins (Bos taurus)
NTPDase5 hydrolyzes nucleoside diphosphates (Bos taurus)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Bos taurus)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Bos taurus)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Bos taurus)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Bos taurus)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Bos taurus)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Bos taurus)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Bos taurus)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Bos taurus)
GMP,IMP [extracellular region]
GMP [extracellular region]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide catabolism (Caenorhabditis elegans)
Phosphate bond hydrolysis by NTPDase proteins (Caenorhabditis elegans)
NTPDase5 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Caenorhabditis elegans)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide catabolism (Canis familiaris)
Phosphate bond hydrolysis by NTPDase proteins (Canis familiaris)
NTPDase5 hydrolyzes nucleoside diphosphates (Canis familiaris)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Canis familiaris)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Canis familiaris)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Canis familiaris)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Canis familiaris)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Canis familiaris)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Canis familiaris)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Canis familiaris)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Canis familiaris)
GMP,IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Canis familiaris)
Binding and Uptake of Ligands by Scavenger Receptors (Canis familiaris)
Scavenging by Class A Receptors (Canis familiaris)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Canis familiaris)
MSR1:Ligand [plasma membrane] (Canis familiaris)
Ligands of MSR1 [extracellular region] (Canis familiaris)
poly(G) [extracellular region]
GMP [extracellular region]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Nucleotide catabolism (Danio rerio)
Phosphate bond hydrolysis by NTPDase proteins (Danio rerio)
NTPDase6 hydrolyzes nucleoside diphosphates (Danio rerio)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Danio rerio)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Danio rerio)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Danio rerio)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Danio rerio)
Sensory perception of taste (Danio rerio)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Danio rerio)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Danio rerio)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Danio rerio)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Danio rerio)
GMP,IMP [extracellular region]
GMP [extracellular region]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide catabolism (Drosophila melanogaster)
Phosphate bond hydrolysis by NTPDase proteins (Drosophila melanogaster)
NTPDase5 hydrolyzes nucleoside diphosphates (Drosophila melanogaster)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Drosophila melanogaster)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Drosophila melanogaster)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Drosophila melanogaster)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Metabolism (Gallus gallus)
Metabolism of nucleotides (Gallus gallus)
Nucleotide catabolism (Gallus gallus)
Phosphate bond hydrolysis by NTPDase proteins (Gallus gallus)
NTPDase5 hydrolyzes nucleoside diphosphates (Gallus gallus)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Gallus gallus)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Gallus gallus)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Gallus gallus)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Gallus gallus)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Gallus gallus)
Binding and Uptake of Ligands by Scavenger Receptors (Gallus gallus)
Scavenging by Class A Receptors (Gallus gallus)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Gallus gallus)
MSR1:Ligand [plasma membrane] (Gallus gallus)
Ligands of MSR1 [extracellular region] (Gallus gallus)
poly(G) [extracellular region]
GMP [extracellular region]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Cell recruitment (pro-inflammatory response) (Homo sapiens)
Purinergic signaling in leishmaniasis infection (Homo sapiens)
NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Phosphate bond hydrolysis by NTPDase proteins (Homo sapiens)
NTPDase5 hydrolyzes nucleoside diphosphates (Homo sapiens)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Homo sapiens)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Homo sapiens)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Homo sapiens)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Homo sapiens)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Homo sapiens)
Sensory perception of taste (Homo sapiens)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
GNAT3 exchanges GDP for GTP in L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 (Homo sapiens)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 dissociates yielding TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP and GNAT3:GTP, and GNB1,3:GNG13 (Homo sapiens)
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GTP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Homo sapiens)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Homo sapiens)
GMP,IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Homo sapiens)
Binding and Uptake of Ligands by Scavenger Receptors (Homo sapiens)
Scavenging by Class A Receptors (Homo sapiens)
MSR1 (SCARA1, SR-A) binds ligands (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
poly(G) [extracellular region]
GMP [extracellular region]
MSR1:Ligand [plasma membrane] (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
poly(G) [extracellular region]
GMP [extracellular region]
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Homo sapiens)
MSR1:Ligand [plasma membrane] (Homo sapiens)
Ligands of MSR1 [extracellular region] (Homo sapiens)
poly(G) [extracellular region]
GMP [extracellular region]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide catabolism (Mus musculus)
Phosphate bond hydrolysis by NTPDase proteins (Mus musculus)
NTPDase5 hydrolyzes nucleoside diphosphates (Mus musculus)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Mus musculus)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Mus musculus)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Mus musculus)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Mus musculus)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Mus musculus)
Sensory perception of taste (Mus musculus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Mus musculus)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Mus musculus)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Mus musculus)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Mus musculus)
GMP,IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Mus musculus)
Binding and Uptake of Ligands by Scavenger Receptors (Mus musculus)
Scavenging by Class A Receptors (Mus musculus)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Mus musculus)
MSR1:Ligand [plasma membrane] (Mus musculus)
Ligands of MSR1 [extracellular region] (Mus musculus)
poly(G) [extracellular region]
GMP [extracellular region]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide catabolism (Plasmodium falciparum)
Phosphate bond hydrolysis by NTPDase proteins (Plasmodium falciparum)
NTPDase5 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Plasmodium falciparum)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide catabolism (Rattus norvegicus)
Phosphate bond hydrolysis by NTPDase proteins (Rattus norvegicus)
NTPDase5 hydrolyzes nucleoside diphosphates (Rattus norvegicus)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Rattus norvegicus)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Rattus norvegicus)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Rattus norvegicus)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Rattus norvegicus)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Rattus norvegicus)
Sensory perception of taste (Rattus norvegicus)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Rattus norvegicus)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Rattus norvegicus)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Rattus norvegicus)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Rattus norvegicus)
GMP,IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Rattus norvegicus)
Binding and Uptake of Ligands by Scavenger Receptors (Rattus norvegicus)
Scavenging by Class A Receptors (Rattus norvegicus)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Rattus norvegicus)
MSR1:Ligand [plasma membrane] (Rattus norvegicus)
Ligands of MSR1 [extracellular region] (Rattus norvegicus)
poly(G) [extracellular region]
GMP [extracellular region]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide catabolism (Saccharomyces cerevisiae)
Phosphate bond hydrolysis by NTPDase proteins (Saccharomyces cerevisiae)
NTPDase5 hydrolyzes nucleoside diphosphates (Saccharomyces cerevisiae)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Saccharomyces cerevisiae)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide catabolism (Schizosaccharomyces pombe)
Phosphate bond hydrolysis by NTPDase proteins (Schizosaccharomyces pombe)
NTPDase5 hydrolyzes nucleoside diphosphates (Schizosaccharomyces pombe)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Schizosaccharomyces pombe)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide catabolism (Sus scrofa)
Phosphate bond hydrolysis by NTPDase proteins (Sus scrofa)
NTPDase5 hydrolyzes nucleoside diphosphates (Sus scrofa)
AMP,GMP,CMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase6 hydrolyzes nucleoside diphosphates (Sus scrofa)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Sus scrofa)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Sus scrofa)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Sus scrofa)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
Sensory Perception (Sus scrofa)
Sensory perception of taste (Sus scrofa)
Sensory perception of sweet, bitter, and umami (glutamate) taste (Sus scrofa)
L-Glutamate or L-Aspartate and 5' nucleotide bind umami taste receptor (TAS1R1:TAS1R3) (Sus scrofa)
GMP,IMP [extracellular region]
GMP [extracellular region]
L-Glu,L-Asp:GMP,IMP:TAS1R1:TAS1R3:GNAT3:GDP:GNB1,3:GNG13 [plasma membrane] (Sus scrofa)
TAS1R1:TAS1R3:L-Glu,L-Asp:GMP,IMP [plasma membrane] (Sus scrofa)
GMP,IMP [extracellular region]
GMP [extracellular region]
Vesicle-mediated transport (Sus scrofa)
Binding and Uptake of Ligands by Scavenger Receptors (Sus scrofa)
Scavenging by Class A Receptors (Sus scrofa)
MSR1:ligand (SCARA1:ligand, SR-A:ligand) is endocytosed (Sus scrofa)
MSR1:Ligand [plasma membrane] (Sus scrofa)
Ligands of MSR1 [extracellular region] (Sus scrofa)
poly(G) [extracellular region]
GMP [extracellular region]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide catabolism (Xenopus tropicalis)
Phosphate bond hydrolysis by NTPDase proteins (Xenopus tropicalis)
NTPDase6 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)
CMP,GMP,IMP,UMP [extracellular region]
GMP [extracellular region]
NTPDase8 hydrolyzes nucleoside diphosphates (Xenopus tropicalis)
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
GMP [extracellular region]
Purine catabolism (Xenopus tropicalis)
NT5E:Zn2+ hydrolyses AMP,dAMP,GMP, IMP (Xenopus tropicalis)
AMP, dAMP, GMP, IMP [extracellular region]
GMP [extracellular region]
External Reference Information
External Reference
guanosine 5'-monophosphate(2-) [ChEBI:58115]
Participates
as a member of
GMP,IMP [extracellular region]
AMP, dAMP, GMP, IMP [extracellular region]
AMP,GMP,CMP,UMP [extracellular region]
CMP,GMP,IMP,UMP [extracellular region]
AMP,GMP,IMP,CMP,TMP,UMP [extracellular region]
as a repeated unit of
poly(G) [extracellular region]
Other forms of this molecule
guanosine 5'-monophosphate [endocytic vesicle lumen]
GMP [Golgi lumen]
GMP [mitochondrial matrix]
GMP [cytosol]
GMP [nucleoplasm]
Cross References
COMPOUND
C00144
ZINC
ZINC000002159505
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