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What is Reactome ?
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Digital Preservation
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CHEST [lipid droplet]
Stable Identifier
R-ALL-163579
Type
Chemical Compound [SimpleEntity]
Compartment
lipid droplet
Synonyms
cholesterol ester, cholesteryl ester
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CHEST [lipid droplet]
Metabolism of lipids (Bos taurus)
Lipid particle organization (Bos taurus)
CIDEA:CIDEC binds lipid droplets (Bos taurus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Bos taurus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Bos taurus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Bos taurus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Bos taurus)
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein clearance (Bos taurus)
LDL clearance (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Bos taurus)
CHEST [lipid droplet]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CHEST [lipid droplet]
Transport of small molecules (Caenorhabditis elegans)
Plasma lipoprotein assembly, remodeling, and clearance (Caenorhabditis elegans)
Plasma lipoprotein clearance (Caenorhabditis elegans)
LDL clearance (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Caenorhabditis elegans)
CHEST [lipid droplet]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Lipid particle organization (Canis familiaris)
CIDEA:CIDEC binds lipid droplets (Canis familiaris)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Canis familiaris)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA binds lipid droplets (Canis familiaris)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA:lipid droplet [lipid droplet] (Canis familiaris)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Canis familiaris)
Plasma lipoprotein assembly, remodeling, and clearance (Canis familiaris)
Plasma lipoprotein clearance (Canis familiaris)
LDL clearance (Canis familiaris)
NCEH1 hydrolyzes cholesterol esters (Canis familiaris)
CHEST [lipid droplet]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase I - Functionalization of compounds (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CHEST [lipid droplet]
Transport of small molecules (Danio rerio)
Plasma lipoprotein assembly, remodeling, and clearance (Danio rerio)
Plasma lipoprotein clearance (Danio rerio)
LDL clearance (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Danio rerio)
CHEST [lipid droplet]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CHEST [lipid droplet]
Transport of small molecules (Dictyostelium discoideum)
Plasma lipoprotein assembly, remodeling, and clearance (Dictyostelium discoideum)
Plasma lipoprotein clearance (Dictyostelium discoideum)
LDL clearance (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Dictyostelium discoideum)
CHEST [lipid droplet]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CHEST [lipid droplet]
Metabolism of lipids (Drosophila melanogaster)
Lipid particle organization (Drosophila melanogaster)
CIDEA:CIDEC binds lipid droplets (Drosophila melanogaster)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Drosophila melanogaster)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Drosophila melanogaster)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Drosophila melanogaster)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Drosophila melanogaster)
Plasma lipoprotein assembly, remodeling, and clearance (Drosophila melanogaster)
Plasma lipoprotein clearance (Drosophila melanogaster)
LDL clearance (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CHEST [lipid droplet]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CHEST [lipid droplet]
Metabolism of lipids (Gallus gallus)
Lipid particle organization (Gallus gallus)
CIDEA:CIDEC binds lipid droplets (Gallus gallus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Gallus gallus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Gallus gallus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Gallus gallus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Gallus gallus)
Plasma lipoprotein assembly, remodeling, and clearance (Gallus gallus)
Plasma lipoprotein clearance (Gallus gallus)
LDL clearance (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Gallus gallus)
CHEST [lipid droplet]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
CHEST [lipid droplet]
Metabolism of lipids (Homo sapiens)
Lipid particle organization (Homo sapiens)
CIDEA:CIDEC binds lipid droplets (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA binds lipid droplets (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA:lipid droplet [lipid droplet] (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Homo sapiens)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Triglyceride metabolism (Homo sapiens)
Triglyceride catabolism (Homo sapiens)
cholesterol ester + H2O -> cholesterol + fatty acid (Homo sapiens)
CHEST [lipid droplet]
Transport of small molecules (Homo sapiens)
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein clearance (Homo sapiens)
LDL clearance (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
CHEST [lipid droplet]
CHEST translocates from ER membrane to lipid particle (Homo sapiens)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Homo sapiens)
CHEST [lipid droplet]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CHEST [lipid droplet]
Metabolism of lipids (Mus musculus)
Lipid particle organization (Mus musculus)
CIDEA:CIDEC binds lipid droplets (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA binds lipid droplets (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA:lipid droplet [lipid droplet] (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Mus musculus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Mus musculus)
Plasma lipoprotein assembly, remodeling, and clearance (Mus musculus)
Plasma lipoprotein clearance (Mus musculus)
LDL clearance (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Mus musculus)
CHEST [lipid droplet]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Lipid particle organization (Rattus norvegicus)
CIDEA:CIDEC binds lipid droplets (Rattus norvegicus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Rattus norvegicus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Rattus norvegicus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Rattus norvegicus)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Rattus norvegicus)
Plasma lipoprotein assembly, remodeling, and clearance (Rattus norvegicus)
Plasma lipoprotein clearance (Rattus norvegicus)
LDL clearance (Rattus norvegicus)
NCEH1 hydrolyzes cholesterol esters (Rattus norvegicus)
CHEST [lipid droplet]
Metabolism (Saccharomyces cerevisiae)
Metabolism of lipids (Saccharomyces cerevisiae)
Lipid particle organization (Saccharomyces cerevisiae)
HSD17B13 binds lipid droplets (Saccharomyces cerevisiae)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Saccharomyces cerevisiae)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Schizosaccharomyces pombe)
Plasma lipoprotein assembly, remodeling, and clearance (Schizosaccharomyces pombe)
Plasma lipoprotein clearance (Schizosaccharomyces pombe)
LDL clearance (Schizosaccharomyces pombe)
NCEH1 hydrolyzes cholesterol esters (Schizosaccharomyces pombe)
CHEST [lipid droplet]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CHEST [lipid droplet]
Metabolism of lipids (Sus scrofa)
Lipid particle organization (Sus scrofa)
CIDEA:CIDEC binds lipid droplets (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA binds lipid droplets (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HILPDA:lipid droplet [lipid droplet] (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Sus scrofa)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
Transport of small molecules (Sus scrofa)
Plasma lipoprotein assembly, remodeling, and clearance (Sus scrofa)
Plasma lipoprotein clearance (Sus scrofa)
LDL clearance (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CHEST [lipid droplet]
NCEH1 hydrolyzes cholesterol esters (Sus scrofa)
CHEST [lipid droplet]
Metabolism (Xenopus tropicalis)
Metabolism of lipids (Xenopus tropicalis)
Lipid particle organization (Xenopus tropicalis)
CIDEA:CIDEC binds lipid droplets (Xenopus tropicalis)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
CIDEA:CIDEC:lipid droplet [lipid droplet] (Xenopus tropicalis)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13 binds lipid droplets (Xenopus tropicalis)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
HSD17B13:lipid droplet [lipid droplet] (Xenopus tropicalis)
lipid droplet [lipid droplet]
CHEST [lipid droplet]
External Reference Information
External Reference
cholesteryl ester [ChEBI:17002]
Participates
as a component of
lipid droplet [lipid droplet]
as an input of
cholesterol ester + H2O -> cholesterol + fatty acid (Rattus norvegicus)
cholesterol ester + H2O -> cholesterol + fatty acid (Homo sapiens)
NCEH1 hydrolyzes cholesterol esters (Schizosaccharomyces pombe)
NCEH1 hydrolyzes cholesterol esters (Dictyostelium discoideum)
NCEH1 hydrolyzes cholesterol esters (Caenorhabditis elegans)
NCEH1 hydrolyzes cholesterol esters (Gallus gallus)
NCEH1 hydrolyzes cholesterol esters (Danio rerio)
NCEH1 hydrolyzes cholesterol esters (Sus scrofa)
NCEH1 hydrolyzes cholesterol esters (Bos taurus)
NCEH1 hydrolyzes cholesterol esters (Canis familiaris)
NCEH1 hydrolyzes cholesterol esters (Rattus norvegicus)
NCEH1 hydrolyzes cholesterol esters (Mus musculus)
NCEH1 hydrolyzes cholesterol esters (Homo sapiens)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Dictyostelium discoideum)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Caenorhabditis elegans)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Drosophila melanogaster)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Gallus gallus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Danio rerio)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Sus scrofa)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Bos taurus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Mus musculus)
CES3 hydrolyses CHEST to CHOL and LCFA(-) (Homo sapiens)
as an output of
CHEST translocates from ER membrane to lipid particle (Homo sapiens)
Other forms of this molecule
CHEST [cytosol]
CHEST [early endosome]
CHEST [endoplasmic reticulum membrane]
cholesterol esters [lysosomal lumen]
cholesterol esters [endosome lumen]
cholesterol esters [endosome membrane]
cholesterol esters [clathrin-coated endocytic vesicle membrane]
CHEST [endoplasmic reticulum lumen]
cholesterol esters [plasma membrane]
CHEST [smooth endoplasmic reticulum]
cholesterol esters [endocytic vesicle lumen]
CHEST [extracellular region]
Cross References
COMPOUND
C02530
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