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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
ReactomeFIViz
Developer's Zone
Graph Database
Analysis Service
Content Service
Pathways Overview
Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
Data Model
Curator Guide
Release Documentation
Computationally inferred events
FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
Species Comparison
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HCYS [cytosol]
Stable Identifier
R-ALL-174369
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
homocysteine, homocysteine zwitterion
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Methylation (Bos taurus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Bos taurus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Choline catabolism (Bos taurus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Bos taurus)
HCYS [cytosol]
Sulfur amino acid metabolism (Bos taurus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Bos taurus)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Bos taurus)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Bos taurus)
HCYS [cytosol]
Cysteine formation from homocysteine (Bos taurus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Bos taurus)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Bos taurus)
Excess homocysteine yields homolanthionine and H2S (Bos taurus)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Bos taurus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
HCYS [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter clearance (Bos taurus)
Dopamine clearance from the synaptic cleft (Bos taurus)
Enzymatic degradation of Dopamine by monoamine oxidase (Bos taurus)
COMT transfers Met to DOPAC to form HVA (Bos taurus)
HCYS [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Methylation (Caenorhabditis elegans)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Caenorhabditis elegans)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Sulfur amino acid metabolism (Caenorhabditis elegans)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Caenorhabditis elegans)
HCYS [cytosol]
Cysteine formation from homocysteine (Caenorhabditis elegans)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Caenorhabditis elegans)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Caenorhabditis elegans)
Excess homocysteine yields homolanthionine and H2S (Caenorhabditis elegans)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
HCYS [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Methylation (Canis familiaris)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Canis familiaris)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Choline catabolism (Canis familiaris)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Canis familiaris)
HCYS [cytosol]
Sulfur amino acid metabolism (Canis familiaris)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Canis familiaris)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Canis familiaris)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Canis familiaris)
HCYS [cytosol]
Cysteine formation from homocysteine (Canis familiaris)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Canis familiaris)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Canis familiaris)
Excess homocysteine yields homolanthionine and H2S (Canis familiaris)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Canis familiaris)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
HCYS [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter clearance (Canis familiaris)
Dopamine clearance from the synaptic cleft (Canis familiaris)
Enzymatic degradation of Dopamine by monoamine oxidase (Canis familiaris)
COMT transfers Met to DOPAC to form HVA (Canis familiaris)
HCYS [cytosol]
Metabolism (Danio rerio)
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Methylation (Danio rerio)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Danio rerio)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Choline catabolism (Danio rerio)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)
HCYS [cytosol]
Sulfur amino acid metabolism (Danio rerio)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Danio rerio)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Danio rerio)
HCYS [cytosol]
Cysteine formation from homocysteine (Danio rerio)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Danio rerio)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Danio rerio)
Excess homocysteine yields homolanthionine and H2S (Danio rerio)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Danio rerio)
HCYS [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter clearance (Danio rerio)
Dopamine clearance from the synaptic cleft (Danio rerio)
Enzymatic degradation of Dopamine by monoamine oxidase (Danio rerio)
COMT transfers Met to DOPAC to form HVA (Danio rerio)
HCYS [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase II - Conjugation of compounds (Dictyostelium discoideum)
Methylation (Dictyostelium discoideum)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Dictyostelium discoideum)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Sulfur amino acid metabolism (Dictyostelium discoideum)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Dictyostelium discoideum)
HCYS [cytosol]
Cysteine formation from homocysteine (Dictyostelium discoideum)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Dictyostelium discoideum)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Dictyostelium discoideum)
Excess homocysteine yields homolanthionine and H2S (Dictyostelium discoideum)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Dictyostelium discoideum)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
HCYS [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Methylation (Drosophila melanogaster)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Drosophila melanogaster)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Sulfur amino acid metabolism (Drosophila melanogaster)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Drosophila melanogaster)
HCYS [cytosol]
Cysteine formation from homocysteine (Drosophila melanogaster)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Drosophila melanogaster)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Drosophila melanogaster)
Excess homocysteine yields homolanthionine and H2S (Drosophila melanogaster)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Drosophila melanogaster)
HCYS [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Methylation (Gallus gallus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Gallus gallus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Choline catabolism (Gallus gallus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Gallus gallus)
HCYS [cytosol]
Sulfur amino acid metabolism (Gallus gallus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Gallus gallus)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Gallus gallus)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Gallus gallus)
HCYS [cytosol]
Cysteine formation from homocysteine (Gallus gallus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Gallus gallus)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Gallus gallus)
Excess homocysteine yields homolanthionine and H2S (Gallus gallus)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Gallus gallus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Cobalamin (Cbl) metabolism (Gallus gallus)
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
HCYS [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter clearance (Gallus gallus)
Dopamine clearance from the synaptic cleft (Gallus gallus)
Enzymatic degradation of Dopamine by monoamine oxidase (Gallus gallus)
COMT transfers Met to DOPAC to form HVA (Gallus gallus)
HCYS [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Defects in vitamin and cofactor metabolism (Homo sapiens)
Defects in cobalamin (B12) metabolism (Homo sapiens)
Defective MTR causes HMAG (Homo sapiens)
Defective MTR does not transfer CH3 group from MeCbl to HCYS (Homo sapiens)
HCYS [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Methylation (Homo sapiens)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Homo sapiens)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Choline catabolism (Homo sapiens)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Homo sapiens)
HCYS [cytosol]
Sulfur amino acid metabolism (Homo sapiens)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Homo sapiens)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Homo sapiens)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Homo sapiens)
HCYS [cytosol]
Cysteine formation from homocysteine (Homo sapiens)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Homo sapiens)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Homo sapiens)
Excess homocysteine yields homolanthionine and H2S (Homo sapiens)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Homo sapiens)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
HCYS [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Dopamine clearance from the synaptic cleft (Homo sapiens)
Enzymatic degradation of Dopamine by monoamine oxidase (Homo sapiens)
COMT transfers Met to DOPAC to form HVA (Homo sapiens)
HCYS [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Methylation (Mus musculus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Mus musculus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Choline catabolism (Mus musculus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)
HCYS [cytosol]
Sulfur amino acid metabolism (Mus musculus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Mus musculus)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Mus musculus)
HCYS [cytosol]
Cysteine formation from homocysteine (Mus musculus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Mus musculus)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Mus musculus)
Excess homocysteine yields homolanthionine and H2S (Mus musculus)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Mus musculus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
HCYS [cytosol]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter clearance (Mus musculus)
Dopamine clearance from the synaptic cleft (Mus musculus)
Enzymatic degradation of Dopamine by monoamine oxidase (Mus musculus)
COMT transfers Met to DOPAC to form HVA (Mus musculus)
HCYS [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Methylation (Rattus norvegicus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Rattus norvegicus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Choline catabolism (Rattus norvegicus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Rattus norvegicus)
HCYS [cytosol]
Sulfur amino acid metabolism (Rattus norvegicus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Rattus norvegicus)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Rattus norvegicus)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Rattus norvegicus)
HCYS [cytosol]
Cysteine formation from homocysteine (Rattus norvegicus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Rattus norvegicus)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Rattus norvegicus)
Excess homocysteine yields homolanthionine and H2S (Rattus norvegicus)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
HCYS [cytosol]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter clearance (Rattus norvegicus)
Dopamine clearance from the synaptic cleft (Rattus norvegicus)
Enzymatic degradation of Dopamine by monoamine oxidase (Rattus norvegicus)
COMT transfers Met to DOPAC to form HVA (Rattus norvegicus)
HCYS [cytosol]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase II - Conjugation of compounds (Saccharomyces cerevisiae)
Methylation (Saccharomyces cerevisiae)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Saccharomyces cerevisiae)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Saccharomyces cerevisiae)
HCYS [cytosol]
Cysteine formation from homocysteine (Saccharomyces cerevisiae)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Saccharomyces cerevisiae)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Saccharomyces cerevisiae)
Excess homocysteine yields homolanthionine and H2S (Saccharomyces cerevisiae)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Saccharomyces cerevisiae)
HCYS [cytosol]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase II - Conjugation of compounds (Schizosaccharomyces pombe)
Methylation (Schizosaccharomyces pombe)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Schizosaccharomyces pombe)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Sulfur amino acid metabolism (Schizosaccharomyces pombe)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Schizosaccharomyces pombe)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Schizosaccharomyces pombe)
Excess homocysteine yields homolanthionine and H2S (Schizosaccharomyces pombe)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Schizosaccharomyces pombe)
HCYS [cytosol]
Neuronal System (Schizosaccharomyces pombe)
Transmission across Chemical Synapses (Schizosaccharomyces pombe)
Neurotransmitter clearance (Schizosaccharomyces pombe)
Dopamine clearance from the synaptic cleft (Schizosaccharomyces pombe)
Enzymatic degradation of Dopamine by monoamine oxidase (Schizosaccharomyces pombe)
COMT transfers Met to DOPAC to form HVA (Schizosaccharomyces pombe)
HCYS [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Methylation (Sus scrofa)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Sus scrofa)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Choline catabolism (Sus scrofa)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Sus scrofa)
HCYS [cytosol]
Sulfur amino acid metabolism (Sus scrofa)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Sus scrofa)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Sus scrofa)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Sus scrofa)
HCYS [cytosol]
Cysteine formation from homocysteine (Sus scrofa)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Sus scrofa)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Sus scrofa)
Excess homocysteine yields homolanthionine and H2S (Sus scrofa)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Sus scrofa)
HCYS [cytosol]
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
HCYS [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Cobalamin (Cbl) metabolism (Sus scrofa)
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
HCYS [cytosol]
Neuronal System (Sus scrofa)
Transmission across Chemical Synapses (Sus scrofa)
Neurotransmitter clearance (Sus scrofa)
Dopamine clearance from the synaptic cleft (Sus scrofa)
Enzymatic degradation of Dopamine by monoamine oxidase (Sus scrofa)
COMT transfers Met to DOPAC to form HVA (Sus scrofa)
HCYS [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Methylation (Xenopus tropicalis)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Xenopus tropicalis)
HCYS [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Choline catabolism (Xenopus tropicalis)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Xenopus tropicalis)
HCYS [cytosol]
Sulfur amino acid metabolism (Xenopus tropicalis)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Xenopus tropicalis)
HCYS [cytosol]
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Xenopus tropicalis)
HCYS [cytosol]
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Xenopus tropicalis)
HCYS [cytosol]
Degradation of cysteine and homocysteine (Xenopus tropicalis)
Excess homocysteine yields homolanthionine and H2S (Xenopus tropicalis)
HCYS [cytosol]
Homocysteine is degraded to oxobutanoate and H2S (Xenopus tropicalis)
HCYS [cytosol]
Neuronal System (Xenopus tropicalis)
Transmission across Chemical Synapses (Xenopus tropicalis)
Neurotransmitter clearance (Xenopus tropicalis)
Dopamine clearance from the synaptic cleft (Xenopus tropicalis)
Enzymatic degradation of Dopamine by monoamine oxidase (Xenopus tropicalis)
COMT transfers Met to DOPAC to form HVA (Xenopus tropicalis)
HCYS [cytosol]
External Reference Information
External Reference
L-homocysteine zwitterion [ChEBI:58199]
Participates
as an input of
Defective MTR does not transfer CH3 group from MeCbl to HCYS (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
Homocysteine is degraded to oxobutanoate and H2S (Saccharomyces cerevisiae)
Homocysteine is degraded to oxobutanoate and H2S (Schizosaccharomyces pombe)
Homocysteine is degraded to oxobutanoate and H2S (Dictyostelium discoideum)
Homocysteine is degraded to oxobutanoate and H2S (Caenorhabditis elegans)
Homocysteine is degraded to oxobutanoate and H2S (Drosophila melanogaster)
Homocysteine is degraded to oxobutanoate and H2S (Xenopus tropicalis)
Homocysteine is degraded to oxobutanoate and H2S (Danio rerio)
Homocysteine is degraded to oxobutanoate and H2S (Sus scrofa)
Homocysteine is degraded to oxobutanoate and H2S (Bos taurus)
Homocysteine is degraded to oxobutanoate and H2S (Canis familiaris)
Homocysteine is degraded to oxobutanoate and H2S (Rattus norvegicus)
Homocysteine is degraded to oxobutanoate and H2S (Mus musculus)
Homocysteine is degraded to oxobutanoate and H2S (Homo sapiens)
Homocysteine is degraded to oxobutanoate and H2S (Gallus gallus)
Excess homocysteine yields homolanthionine and H2S (Saccharomyces cerevisiae)
Excess homocysteine yields homolanthionine and H2S (Schizosaccharomyces pombe)
Excess homocysteine yields homolanthionine and H2S (Dictyostelium discoideum)
Excess homocysteine yields homolanthionine and H2S (Caenorhabditis elegans)
Excess homocysteine yields homolanthionine and H2S (Drosophila melanogaster)
Excess homocysteine yields homolanthionine and H2S (Xenopus tropicalis)
Excess homocysteine yields homolanthionine and H2S (Danio rerio)
Excess homocysteine yields homolanthionine and H2S (Sus scrofa)
Excess homocysteine yields homolanthionine and H2S (Bos taurus)
Excess homocysteine yields homolanthionine and H2S (Canis familiaris)
Excess homocysteine yields homolanthionine and H2S (Rattus norvegicus)
Excess homocysteine yields homolanthionine and H2S (Mus musculus)
Excess homocysteine yields homolanthionine and H2S (Homo sapiens)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Mus musculus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Homo sapiens)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Rattus norvegicus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Canis familiaris)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Bos taurus)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Sus scrofa)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Danio rerio)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Xenopus tropicalis)
BHMT tetramer transfers CH3 group from BET to HCYS to form DMGLY (Gallus gallus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Homo sapiens)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Mus musculus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Rattus norvegicus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Canis familiaris)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Bos taurus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Sus scrofa)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Danio rerio)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Gallus gallus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Drosophila melanogaster)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Caenorhabditis elegans)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Dictyostelium discoideum)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Saccharomyces cerevisiae)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Gallus gallus)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Homo sapiens)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Mus musculus)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Rattus norvegicus)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Canis familiaris)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Bos taurus)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Sus scrofa)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Danio rerio)
BHMT2 tetramer transfers CH3 group from SMM to LHCYS (Xenopus tropicalis)
Excess homocysteine yields homolanthionine and H2S (Gallus gallus)
as an output of
COMT transfers Met to DOPAC to form HVA (Schizosaccharomyces pombe)
COMT transfers Met to DOPAC to form HVA (Gallus gallus)
COMT transfers Met to DOPAC to form HVA (Xenopus tropicalis)
COMT transfers Met to DOPAC to form HVA (Danio rerio)
COMT transfers Met to DOPAC to form HVA (Sus scrofa)
COMT transfers Met to DOPAC to form HVA (Bos taurus)
COMT transfers Met to DOPAC to form HVA (Canis familiaris)
COMT transfers Met to DOPAC to form HVA (Rattus norvegicus)
COMT transfers Met to DOPAC to form HVA (Mus musculus)
COMT transfers Met to DOPAC to form HVA (Homo sapiens)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Mus musculus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Homo sapiens)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Rattus norvegicus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Canis familiaris)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Bos taurus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Sus scrofa)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Danio rerio)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Xenopus tropicalis)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Gallus gallus)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Drosophila melanogaster)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Caenorhabditis elegans)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Dictyostelium discoideum)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Schizosaccharomyces pombe)
AHCY:NAD+ tetramer hydrolyses AdoHcy (Saccharomyces cerevisiae)
This entity regulates
Positively
Excess homocysteine yields homolanthionine and H2S
(Saccharomyces cerevisiae)
Excess homocysteine yields homolanthionine and H2S
(Schizosaccharomyces pombe)
Excess homocysteine yields homolanthionine and H2S
(Dictyostelium discoideum)
Excess homocysteine yields homolanthionine and H2S
(Caenorhabditis elegans)
Excess homocysteine yields homolanthionine and H2S
(Drosophila melanogaster)
Excess homocysteine yields homolanthionine and H2S
(Xenopus tropicalis)
Excess homocysteine yields homolanthionine and H2S
(Danio rerio)
Excess homocysteine yields homolanthionine and H2S
(Sus scrofa)
Excess homocysteine yields homolanthionine and H2S
(Bos taurus)
Excess homocysteine yields homolanthionine and H2S
(Canis familiaris)
Excess homocysteine yields homolanthionine and H2S
(Rattus norvegicus)
Excess homocysteine yields homolanthionine and H2S
(Mus musculus)
Excess homocysteine yields homolanthionine and H2S
(Homo sapiens)
Excess homocysteine yields homolanthionine and H2S
(Gallus gallus)
Cross References
ZINC
000000895077
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