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11DCORST [cytosol]
Stable Identifier
R-ALL-194037
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
cortexone, 11-deoxycorticosterone
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
ATP hydrolysis by HSP90 (Bos taurus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Bos taurus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Bos taurus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Bos taurus)
NR3C2:NR3C2 ligands [cytosol] (Bos taurus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Bos taurus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Bos taurus)
NR3C2:NR3C2 ligands [cytosol] (Bos taurus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Cytochrome P450 - arranged by substrate type (Bos taurus)
Endogenous sterols (Bos taurus)
CYP21A2 21-hydroxylates PROG (Bos taurus)
11DCORST [cytosol]
Metabolism of lipids (Bos taurus)
Metabolism of steroids (Bos taurus)
Metabolism of steroid hormones (Bos taurus)
Mineralocorticoid biosynthesis (Bos taurus)
CYP21A2 21-hydroxylates PROG (Bos taurus)
11DCORST [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Canis familiaris)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Canis familiaris)
NR3C2:NR3C2 ligands [cytosol] (Canis familiaris)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Canis familiaris)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Canis familiaris)
NR3C2:NR3C2 ligands [cytosol] (Canis familiaris)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Cytochrome P450 - arranged by substrate type (Canis familiaris)
Endogenous sterols (Canis familiaris)
CYP21A2 21-hydroxylates PROG (Canis familiaris)
11DCORST [cytosol]
Metabolism of lipids (Canis familiaris)
Metabolism of steroids (Canis familiaris)
Metabolism of steroid hormones (Canis familiaris)
Mineralocorticoid biosynthesis (Canis familiaris)
CYP21A2 21-hydroxylates PROG (Canis familiaris)
11DCORST [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Danio rerio)
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Danio rerio)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Danio rerio)
NR3C2:NR3C2 ligands [cytosol] (Danio rerio)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Danio rerio)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Danio rerio)
NR3C2:NR3C2 ligands [cytosol] (Danio rerio)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Cytochrome P450 - arranged by substrate type (Dictyostelium discoideum)
Endogenous sterols (Dictyostelium discoideum)
CYP21A2 21-hydroxylates PROG (Dictyostelium discoideum)
11DCORST [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Metabolism of steroids (Dictyostelium discoideum)
Metabolism of steroid hormones (Dictyostelium discoideum)
Mineralocorticoid biosynthesis (Dictyostelium discoideum)
CYP21A2 21-hydroxylates PROG (Dictyostelium discoideum)
11DCORST [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Drosophila melanogaster)
ATP hydrolysis by HSP90 (Drosophila melanogaster)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Drosophila melanogaster)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Drosophila melanogaster)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Drosophila melanogaster)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
NR3C2:NR3C2 ligands [cytosol] (Drosophila melanogaster)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Gallus gallus)
ATP hydrolysis by HSP90 (Gallus gallus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Gallus gallus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Gallus gallus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Gallus gallus)
NR3C2:NR3C2 ligands [cytosol] (Gallus gallus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Gallus gallus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Gallus gallus)
NR3C2:NR3C2 ligands [cytosol] (Gallus gallus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Cytochrome P450 - arranged by substrate type (Gallus gallus)
Endogenous sterols (Gallus gallus)
CYP21A2 21-hydroxylates PROG (Gallus gallus)
11DCORST [cytosol]
Metabolism of lipids (Gallus gallus)
Metabolism of steroids (Gallus gallus)
Metabolism of steroid hormones (Gallus gallus)
Mineralocorticoid biosynthesis (Gallus gallus)
CYP21A2 21-hydroxylates PROG (Gallus gallus)
11DCORST [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Homo sapiens)
ATP hydrolysis by HSP90 (Homo sapiens)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Homo sapiens)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Homo sapiens)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Homo sapiens)
NR3C2:NR3C2 ligands [cytosol] (Homo sapiens)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Homo sapiens)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Homo sapiens)
NR3C2:NR3C2 ligands [cytosol] (Homo sapiens)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Cytochrome P450 - arranged by substrate type (Homo sapiens)
Endogenous sterols (Homo sapiens)
CYP21A2 21-hydroxylates PROG (Homo sapiens)
11DCORST [cytosol]
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Metabolism of steroid hormones (Homo sapiens)
Mineralocorticoid biosynthesis (Homo sapiens)
11DCORST translocates from cytosol to mitochondrial matrix (Homo sapiens)
11DCORST [cytosol]
CYP21A2 21-hydroxylates PROG (Homo sapiens)
11DCORST [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Mus musculus)
ATP hydrolysis by HSP90 (Mus musculus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Mus musculus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Mus musculus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Mus musculus)
NR3C2:NR3C2 ligands [cytosol] (Mus musculus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Mus musculus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Mus musculus)
NR3C2:NR3C2 ligands [cytosol] (Mus musculus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Cytochrome P450 - arranged by substrate type (Mus musculus)
Endogenous sterols (Mus musculus)
CYP21A2 21-hydroxylates PROG (Mus musculus)
11DCORST [cytosol]
Metabolism of lipids (Mus musculus)
Metabolism of steroids (Mus musculus)
Metabolism of steroid hormones (Mus musculus)
Mineralocorticoid biosynthesis (Mus musculus)
CYP21A2 21-hydroxylates PROG (Mus musculus)
11DCORST [cytosol]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Plasmodium falciparum)
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Plasmodium falciparum)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Plasmodium falciparum)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Plasmodium falciparum)
NR3C2:NR3C2 ligands [cytosol] (Plasmodium falciparum)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Plasmodium falciparum)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Plasmodium falciparum)
NR3C2:NR3C2 ligands [cytosol] (Plasmodium falciparum)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Rattus norvegicus)
ATP hydrolysis by HSP90 (Rattus norvegicus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Rattus norvegicus)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Rattus norvegicus)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Rattus norvegicus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
NR3C2:NR3C2 ligands [cytosol] (Rattus norvegicus)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Cytochrome P450 - arranged by substrate type (Rattus norvegicus)
Endogenous sterols (Rattus norvegicus)
CYP21A2 21-hydroxylates PROG (Rattus norvegicus)
11DCORST [cytosol]
Metabolism of lipids (Rattus norvegicus)
Metabolism of steroids (Rattus norvegicus)
Metabolism of steroid hormones (Rattus norvegicus)
Mineralocorticoid biosynthesis (Rattus norvegicus)
CYP21A2 21-hydroxylates PROG (Rattus norvegicus)
11DCORST [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Sus scrofa)
ATP hydrolysis by HSP90 (Sus scrofa)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
FKBP4 replaces FKBP5 within HSP90:ATP:FKBP5:unfolded protein (Sus scrofa)
SH [cytosol]
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:p23:FKBP52:SHR:SH translocates to the nucleus (Sus scrofa)
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Sus scrofa)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
NR3C2:NR3C2 ligands [cytosol] (Sus scrofa)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Cytochrome P450 - arranged by substrate type (Sus scrofa)
Endogenous sterols (Sus scrofa)
CYP21A2 21-hydroxylates PROG (Sus scrofa)
11DCORST [cytosol]
Metabolism of lipids (Sus scrofa)
Metabolism of steroids (Sus scrofa)
Metabolism of steroid hormones (Sus scrofa)
Mineralocorticoid biosynthesis (Sus scrofa)
CYP21A2 21-hydroxylates PROG (Sus scrofa)
11DCORST [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Xenopus tropicalis)
NR3C2 ligands bind NR3C2 (in the HSP90 chaperone complex) (Xenopus tropicalis)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
HSP90:ATP:FKBP4:PTGES3:NR3C2:NR3C2 ligands [cytosol] (Xenopus tropicalis)
NR3C2:NR3C2 ligands [cytosol] (Xenopus tropicalis)
NR3C2 ligands [cytosol]
11DCORST [cytosol]
External Reference Information
External Reference
11-deoxycorticosterone [ChEBI:16973]
Participates
as an output of
CYP21A2 21-hydroxylates PROG (Dictyostelium discoideum)
CYP21A2 21-hydroxylates PROG (Gallus gallus)
CYP21A2 21-hydroxylates PROG (Sus scrofa)
CYP21A2 21-hydroxylates PROG (Bos taurus)
CYP21A2 21-hydroxylates PROG (Canis familiaris)
CYP21A2 21-hydroxylates PROG (Rattus norvegicus)
CYP21A2 21-hydroxylates PROG (Mus musculus)
CYP21A2 21-hydroxylates PROG (Homo sapiens)
as an input of
11DCORST translocates from cytosol to mitochondrial matrix (Homo sapiens)
as a member of
NR3C2 ligands [cytosol]
Other forms of this molecule
11DCORST [mitochondrial matrix]
11DCORST [extracellular region]
11DCORST [nucleoplasm]
Cross References
COMPOUND
C03205
HMDB Metabolite
HMDB0000016
ZINC
000003833823
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