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What is Reactome ?
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ADP [cytosol]
Stable Identifier
R-ALL-29370
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Adenosine 5'-diphosphate, ADP(3-)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Bos taurus)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Bos taurus)
ADP [cytosol]
Selective autophagy (Bos taurus)
Mitophagy (Bos taurus)
Receptor Mediated Mitophagy (Bos taurus)
FUNDC1 is phosphorylated by CK2 (Bos taurus)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Bos taurus)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Bos taurus)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Bos taurus)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
ADP [cytosol]
Cell Cycle (Bos taurus)
Cell Cycle Checkpoints (Bos taurus)
G2/M Checkpoints (Bos taurus)
G2/M DNA replication checkpoint (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
ADP [cytosol]
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Metaphase and Anaphase (Bos taurus)
Mitotic Anaphase (Bos taurus)
Nuclear Envelope (NE) Reassembly (Bos taurus)
Initiation of Nuclear Envelope (NE) Reformation (Bos taurus)
CDK1 phosphorylates LBR (Bos taurus)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
ADP [cytosol]
Mitotic Prometaphase (Bos taurus)
Condensation of Prometaphase Chromosomes (Bos taurus)
CK2 phosphorylates condensin I subunits (Bos taurus)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Bos taurus)
NEK6 and NEK7 phosphorylate EML4 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates NUDC (Bos taurus)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Bos taurus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Bos taurus)
ADP [cytosol]
Mitotic Prophase (Bos taurus)
Golgi Cisternae Pericentriolar Stack Reorganization (Bos taurus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Bos taurus)
ADP [cytosol]
Nuclear Envelope Breakdown (Bos taurus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Bos taurus)
CDK1:CCNB phosphorylates NEK9 (Bos taurus)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Bos taurus)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Bos taurus)
CDK1 phosphorylates NUP98 (Bos taurus)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Bos taurus)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Bos taurus)
G1 Phase (Bos taurus)
Cyclin D associated events in G1 (Bos taurus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Bos taurus)
ADP [cytosol]
G1/S Transition (Bos taurus)
Cyclin E associated events during G1/S transition (Bos taurus)
SCF(Skp2)-mediated degradation of p27/p21 (Bos taurus)
PTK6 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
Mitotic G2-G2/M phases (Bos taurus)
G2/M Transition (Bos taurus)
AURKA Activation by TPX2 (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
ADP [cytosol]
Centrosome maturation (Bos taurus)
Loss of proteins required for interphase microtubule organization from the centrosome (Bos taurus)
Loss of Nlp from mitotic centrosomes (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Bos taurus)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Bos taurus)
AURKA phosphorylates PHLDA1 (Bos taurus)
ADP [cytosol]
Polo-like kinase mediated events (Bos taurus)
Activation of Cdc25C (Bos taurus)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
ADP [cytosol]
AURKA phosphorylates PLK1 (Bos taurus)
ADP [cytosol]
CDK1 phosphorylates BORA (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates BORA (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates OPTN (Bos taurus)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Bos taurus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Bos taurus)
ADP [cytosol]
S Phase (Bos taurus)
Cyclin A:Cdk2-associated events at S phase entry (Bos taurus)
SCF(Skp2)-mediated degradation of p27/p21 (Bos taurus)
PTK6 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
Cell-Cell communication (Bos taurus)
Nephrin family interactions (Bos taurus)
Phosphorylation of nephrin by FYN (Bos taurus)
ADP [cytosol]
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
MAP3K5 phosphorylates MKK3 and MKK6 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Cellular response to chemical stress (Bos taurus)
KEAP1-NFE2L2 pathway (Bos taurus)
Nuclear events mediated by NFE2L2 (Bos taurus)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Bos taurus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Bos taurus)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Bos taurus)
ADP [cytosol]
Cellular response to heat stress (Bos taurus)
Regulation of HSF1-mediated heat shock response (Bos taurus)
Constitutive phosphorylation by pERK1/2 (Bos taurus)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Bos taurus)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Bos taurus)
ADP [cytosol]
HSP70s:ADP [cytosol] (Bos taurus)
HSP13:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP14:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA6:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Bos taurus)
HSP70s:ADP [cytosol] (Bos taurus)
HSP13:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP14:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA6:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Bos taurus)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Bos taurus)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Bos taurus)
ATP binding to HSP90 triggers conformation change (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
ATP hydrolysis by HSP70 (Bos taurus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Bos taurus)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Bos taurus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Bos taurus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Bos taurus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Bos taurus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Bos taurus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Bos taurus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Unfolded Protein Response (UPR) (Bos taurus)
IRE1alpha activates chaperones (Bos taurus)
IRE1 dimer autophosphorylates (Bos taurus)
ADP [cytosol]
PERK regulates gene expression (Bos taurus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Bos taurus)
ADP [cytosol]
DNA Replication (Bos taurus)
DNA Replication Pre-Initiation (Bos taurus)
Assembly of the pre-replicative complex (Bos taurus)
Assembly of the ORC complex at the origin of replication (Bos taurus)
ORC6 is phosphorylated on T195 (Bos taurus)
ADP [cytosol]
Developmental Biology (Bos taurus)
MITF-M-regulated melanocyte development (Bos taurus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Bos taurus)
MAPK-dependent phosphorylation of KARS (Bos taurus)
ADP [cytosol]
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
EPH-Ephrin signaling (Bos taurus)
EPH receptors autophosphorylate (Bos taurus)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Bos taurus)
SFKs phosphorylate VAV2,3 (Bos taurus)
ADP [cytosol]
EPHB-mediated forward signaling (Bos taurus)
PAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Bos taurus)
ADP [cytosol]
Ephrin signaling (Bos taurus)
PAKs autophosphorylate (Bos taurus)
ADP [cytosol]
PAKs phosphorylate MLC (Bos taurus)
ADP [cytosol]
L1CAM interactions (Bos taurus)
Recycling pathway of L1 (Bos taurus)
Phosphorylation of L1 by ERK (Bos taurus)
ADP [cytosol]
Signal transduction by L1 (Bos taurus)
Interaction of PAK1 with Rac1-GTP (Bos taurus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Bos taurus)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Bos taurus)
ADP [cytosol]
Netrin-1 signaling (Bos taurus)
DCC mediated attractive signaling (Bos taurus)
Phosphorylation of DCC by Fyn (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Bos taurus)
ADP [cytosol]
RET signaling (Bos taurus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Bos taurus)
ADP [cytosol]
RET tyrosine phosphorylation (Bos taurus)
ADP [cytosol]
Reelin signalling pathway (Bos taurus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Bos taurus)
ADP [cytosol]
Semaphorin interactions (Bos taurus)
CRMPs in Sema3A signaling (Bos taurus)
Phosphorylation of CRMPs by Cdk5 (Bos taurus)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Bos taurus)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Bos taurus)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Bos taurus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Bos taurus)
ADP [cytosol]
Sema4D in semaphorin signaling (Bos taurus)
Sema4D induced cell migration and growth-cone collapse (Bos taurus)
SEMA4D interacts with Plexin-B1:ErbB2 (Bos taurus)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Bos taurus)
SEMA4D interacts with Plexin-B1:Met (Bos taurus)
ADP [cytosol]
Signaling by ROBO receptors (Bos taurus)
Role of ABL in ROBO-SLIT signaling (Bos taurus)
Phosphorylation of ROBO1 by ABL kinase (Bos taurus)
ADP [cytosol]
Drug ADME (Bos taurus)
Aspirin ADME (Bos taurus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Bos taurus)
ADP [cytosol]
Azathioprine ADME (Bos taurus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Bos taurus)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Bos taurus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Bos taurus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Bos taurus)
ADP [cytosol]
Ciprofloxacin ADME (Bos taurus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Bos taurus)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Bos taurus)
ADP [cytosol]
Paracetamol ADME (Bos taurus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Bos taurus)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Bos taurus)
ADP [cytosol]
Prednisone ADME (Bos taurus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Bos taurus)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Bos taurus)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Bos taurus)
ADP [cytosol]
Ribavirin ADME (Bos taurus)
ADK phosphorylates RBV (Bos taurus)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Bos taurus)
ADP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Bos taurus)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Bos taurus)
PLK2 phosphorylates CENPJ (Bos taurus)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Bos taurus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Bos taurus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Bos taurus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Bos taurus)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Bos taurus)
Regulation of RUNX3 expression and activity (Bos taurus)
SRC phosphorylates RUNX3 (Bos taurus)
ADP [cytosol]
Hemostasis (Bos taurus)
Cell surface interactions at the vascular wall (Bos taurus)
PECAM1 interactions (Bos taurus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Bos taurus)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Bos taurus)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Bos taurus)
ADP [cytosol]
Kinesins (Bos taurus)
Kinesins move along microtubules consuming ATP (Bos taurus)
ADP [cytosol]
Platelet activation, signaling and aggregation (Bos taurus)
Effects of PIP2 hydrolysis (Bos taurus)
DAG kinase produces phosphatidic acid from DAG (Bos taurus)
ADP [cytosol]
GPVI-mediated activation cascade (Bos taurus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Bos taurus)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
SYK autophosphorylates (Bos taurus)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Bos taurus)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Bos taurus)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Bos taurus)
Integrin signaling (Bos taurus)
Autophosphorylation of PTK2 at Y397 (Bos taurus)
ADP [cytosol]
Autophosphorylation of SRC (Bos taurus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Bos taurus)
ADP [cytosol]
SYK activation by SRC (Bos taurus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Bos taurus)
Disinhibition of SNARE formation (Bos taurus)
Phosphorylation of Platelet Sec-1 (Bos taurus)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Bos taurus)
ADP [cytosol]
Platelet degranulation (Bos taurus)
ABCC4 accumulation of dense granule contents (Bos taurus)
ADP [cytosol]
Signal amplification (Bos taurus)
ADP signalling through P2Y purinoceptor 1 (Bos taurus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)
ADP [cytosol]
Platelet homeostasis (Bos taurus)
Platelet sensitization by LDL (Bos taurus)
FGR binds and phosphorylates LRP8 (Bos taurus)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Bos taurus)
ADP [cytosol]
PECAM1 is phosphorylated (Bos taurus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)
ADP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Bos taurus)
Transport of Antigen peptide in to ER (Bos taurus)
ADP [cytosol]
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent PI3K/Akt signaling (Bos taurus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Bos taurus)
ADP [cytosol]
CD28 dependent Vav1 pathway (Bos taurus)
Activation of Vav1 (Bos taurus)
ADP [cytosol]
Phosphorylation of CD28 (Bos taurus)
ADP [cytosol]
CTLA4 inhibitory signaling (Bos taurus)
Phosphorylation of CTLA-4 (Bos taurus)
ADP [cytosol]
PD-1 signaling (Bos taurus)
Phosphorylation of PD-1 (Bos taurus)
ADP [cytosol]
MHC class II antigen presentation (Bos taurus)
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
ADP [cytosol]
Rap1 signalling (Bos taurus)
PKA/PKG phosphorylate Rap1GAP2 (Bos taurus)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Bos taurus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Bos taurus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Bos taurus)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Bos taurus)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Bos taurus)
ADP [cytosol]
CD22 mediated BCR regulation (Bos taurus)
LYN phosphorylates CD22 (Bos taurus)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Bos taurus)
Activation of NF-kappaB in B cells (Bos taurus)
Activated IKK phosphorylates I-kappaB (Bos taurus)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Bos taurus)
ADP [cytosol]
TCR signaling (Bos taurus)
Downstream TCR signaling (Bos taurus)
Activation of IKK complex (Bos taurus)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Bos taurus)
ADP [cytosol]
Change of PKC theta conformation (Bos taurus)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation of Bcl10 (Bos taurus)
ADP [cytosol]
Phosphorylation of CARMA1 (Bos taurus)
ADP [cytosol]
Phosphorylation of PKC theta (Bos taurus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
ADP [cytosol]
Generation of second messenger molecules (Bos taurus)
Phosphorylation of PLC-gamma1 (Bos taurus)
ADP [cytosol]
Phosphorylation of SLP-76 (Bos taurus)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Bos taurus)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Bos taurus)
Activation of Lck (Bos taurus)
ADP [cytosol]
Inactivation of Lck by Csk (Bos taurus)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Bos taurus)
Activation of ZAP-70 (Bos taurus)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Bos taurus)
ADP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
FLT3 Signaling (Bos taurus)
Active FLT3 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
FLT3 phosphorylates GRB10 (Bos taurus)
ADP [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Bos taurus)
ADP [cytosol]
Negative regulation of FLT3 (Bos taurus)
FLT3 phosphorylates CBL (Bos taurus)
ADP [cytosol]
Growth hormone receptor signaling (Bos taurus)
Lyn activates ERK (Bos taurus)
ADP [cytosol]
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
PKR-mediated signaling (Bos taurus)
p-PKR dimer phosphorylates CDK1 (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Bos taurus)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Bos taurus)
ADP [cytosol]
Interferon alpha/beta signaling (Bos taurus)
Activation of JAK kinases (Bos taurus)
ADP [cytosol]
Formation of p-STAT1 homodimer (Bos taurus)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Bos taurus)
ADP [cytosol]
Phosphorylation of STAT2 (Bos taurus)
ADP [cytosol]
Interferon gamma signaling (Bos taurus)
IFNG signaling activates MAPKs (Bos taurus)
JAK1-activated RAF1 phosphorylates MAPKs (Bos taurus)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Bos taurus)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Bos taurus)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)
ADP [cytosol]
Phosphorylation of JAK2 (Bos taurus)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Bos taurus)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Bos taurus)
ADP [cytosol]
Transphosphorylation of JAK1 (Bos taurus)
ADP [cytosol]
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
IKBA is phosphorylated by Phospho IKKB kinase (Bos taurus)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Bos taurus)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Bos taurus)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Bos taurus)
ADP [cytosol]
Interleukin-37 signaling (Bos taurus)
STAT3 phosphorylation (Bos taurus)
ADP [cytosol]
TBK1 phosphorylation (Bos taurus)
ADP [cytosol]
Interleukin-38 signaling (Bos taurus)
MAPK8 phosphorylation (Bos taurus)
ADP [cytosol]
Interleukin-10 signaling (Bos taurus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Bos taurus)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Bos taurus)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Bos taurus)
ADP [cytosol]
Interleukin-12 family signaling (Bos taurus)
Interleukin-12 signaling (Bos taurus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Bos taurus)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Bos taurus)
ADP [cytosol]
Interleukin-23 signaling (Bos taurus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Bos taurus)
ADP [cytosol]
Interleukin-27 signaling (Bos taurus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Bos taurus)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Bos taurus)
ADP [cytosol]
Interleukin-35 Signalling (Bos taurus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Bos taurus)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Bos taurus)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Bos taurus)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Bos taurus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Bos taurus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Bos taurus)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Bos taurus)
ADP [cytosol]
Interleukin-17 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
Interleukin-2 family signaling (Bos taurus)
Interleukin receptor SHC signaling (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
ADP [cytosol]
Interleukin-15 signaling (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Bos taurus)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)
ADP [cytosol]
Interleukin-2 signaling (Bos taurus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Bos taurus)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Bos taurus)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Bos taurus)
ADP [cytosol]
SYK is a substrate for JAK1 (Bos taurus)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)
ADP [cytosol]
Interleukin-21 signaling (Bos taurus)
IL21 receptor JAK phosphorylation (Bos taurus)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Bos taurus)
ADP [cytosol]
Interleukin-9 signaling (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Bos taurus)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Bos taurus)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)
ADP [cytosol]
Interleukin-20 family signaling (Bos taurus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Bos taurus)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Bos taurus)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Bos taurus)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Bos taurus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Bos taurus)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Bos taurus)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Bos taurus)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Bos taurus)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Bos taurus)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Bos taurus)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Bos taurus)
Activation of STAT5a/b by JAK2 (Bos taurus)
ADP [cytosol]
Interleukin receptor SHC signaling (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
ADP [cytosol]
JAK2 is phosphorylated, activated (Bos taurus)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Bos taurus)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Bos taurus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Bos taurus)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Bos taurus)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Bos taurus)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Bos taurus)
ADP [cytosol]
Interleukin-6 family signaling (Bos taurus)
Interleukin-6 signaling (Bos taurus)
IL6ST is tyrosine phosphorylated (Bos taurus)
ADP [cytosol]
JAK activation (Bos taurus)
ADP [cytosol]
PTPN11 is phosphorylated (Bos taurus)
ADP [cytosol]
Serine phosphorylation of STATs (Bos taurus)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Bos taurus)
ADP [cytosol]
Interleukin-7 signaling (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Bos taurus)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Bos taurus)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Bos taurus)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Bos taurus)
NIK-->noncanonical NF-kB signaling (Bos taurus)
Active NIK phosphorylates IKKA dimer (Bos taurus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)
ADP [cytosol]
NIK autophosphorylates on T559 (Bos taurus)
ADP [cytosol]
Innate Immune System (Bos taurus)
Alpha-protein kinase 1 signaling pathway (Bos taurus)
ALPK1 phosphorylates TIFA (Bos taurus)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Bos taurus)
ADP [cytosol]
C-type lectin receptors (CLRs) (Bos taurus)
CLEC7A (Dectin-1) signaling (Bos taurus)
Dectin-1 mediated noncanonical NF-kB signaling (Bos taurus)
Active NIK phosphorylates IKKA dimer (Bos taurus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Bos taurus)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Bos taurus)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Bos taurus)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Bos taurus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
ADP [cytosol]
Dectin-2 family (Bos taurus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Bos taurus)
ADP [cytosol]
SYK autophosphorylates (Bos taurus)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Bos taurus)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Bos taurus)
STING mediated induction of host immune responses (Bos taurus)
IRF3-mediated induction of type I IFN (Bos taurus)
IRF3 is phosphorylated by TBK1 (Bos taurus)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Bos taurus)
ADP [cytosol]
STAT6-mediated induction of chemokines (Bos taurus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Bos taurus)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Bos taurus)
RIP-mediated NFkB activation via ZBP1 (Bos taurus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
DAP12 interactions (Bos taurus)
DAP12 signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Bos taurus)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Bos taurus)
TRAF6 mediated NF-kB activation (Bos taurus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Bos taurus)
Autophosphorylation of LYN kinase (Bos taurus)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Bos taurus)
Autophosphorylation of BTK/ITK (Bos taurus)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Bos taurus)
ADP [cytosol]
FCERI mediated MAPK activation (Bos taurus)
Autophosphorylation of PAK (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of VAV (Bos taurus)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Bos taurus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
FCERI mediated NF-kB activation (Bos taurus)
Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
ADP [cytosol]
Autophosphorylation of PKC-theta (Bos taurus)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Bos taurus)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of PKC-theta (Bos taurus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Bos taurus)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Bos taurus)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Bos taurus)
Phosphorylation of NTAL by p-SYK/Lyn (Bos taurus)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Bos taurus)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Bos taurus)
FCGR activation (Bos taurus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Bos taurus)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Bos taurus)
ABL phosphorylates WAVEs (Bos taurus)
ADP [cytosol]
Autophosphorylation of PAK1 (Bos taurus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Bos taurus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Bos taurus)
Actin:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Detachment of WASP/WAVE (Bos taurus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Bos taurus)
Actin:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Bos taurus)
Actin filament bound Myosin-X [plasma membrane] (Bos taurus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Bos taurus)
ADP [cytosol]
Phosphorylation of VAV (Bos taurus)
ADP [cytosol]
Role of myosins in phagosome formation (Bos taurus)
Myosin-Actin filaments [cytosol] (Bos taurus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Bos taurus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Bos taurus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
ADP [cytosol]
Role of phospholipids in phagocytosis (Bos taurus)
DAG stimulates protein kinase C-delta (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of PLCG (Bos taurus)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Bos taurus)
NOD1/2 Signaling Pathway (Bos taurus)
Activation of p38 MAPK (Bos taurus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Bos taurus)
ADP [cytosol]
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK1 recruits IKK complex (Bos taurus)
IRAK1 phosphorylates Pellino (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK1 recruits IKK complex (Bos taurus)
IRAK1 phosphorylates Pellino (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK1 recruits IKK complex (Bos taurus)
IRAK1 phosphorylates Pellino (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Bos taurus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Bos taurus)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Bos taurus)
Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
IRAK1 recruits IKK complex (Bos taurus)
IRAK1 phosphorylates Pellino (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
IRAK1 recruits IKK complex (Bos taurus)
IRAK1 phosphorylates Pellino (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Bos taurus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Bos taurus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Bos taurus)
ADP [cytosol]
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
ADP [cytosol]
MAP3K8 is phosphorylated (Bos taurus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
ADP [cytosol]
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Pyruvate metabolism (Bos taurus)
PKM dephosphorylates PEP to PYR (Bos taurus)
ADP [cytosol]
Regulation of pyruvate metabolism (Bos taurus)
NEK1 phosphorylates ME1 (Bos taurus)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Bos taurus)
Mitochondrial Uncoupling (Bos taurus)
The proton buffering model (Bos taurus)
Protons are translocated from the intermembrane space to the matrix (Bos taurus)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
Transport and synthesis of PAPS (Bos taurus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Bos taurus)
ADP [cytosol]
Glutathione conjugation (Bos taurus)
Glutathione synthesis and recycling (Bos taurus)
GCL ligates L-Glu to L-Cys (Bos taurus)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Bos taurus)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Bos taurus)
ADP [cytosol]
Inositol phosphate metabolism (Bos taurus)
Synthesis of IP3 and IP4 in the cytosol (Bos taurus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Bos taurus)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Bos taurus)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Bos taurus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Bos taurus)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Bos taurus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Bos taurus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Bos taurus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Bos taurus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Bos taurus)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Bos taurus)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Bos taurus)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Bos taurus)
ADP [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Bos taurus)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Creatine metabolism (Bos taurus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Bos taurus)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Bos taurus)
ADP [cytosol]
Glutamate and glutamine metabolism (Bos taurus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Bos taurus)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Bos taurus)
ADP [cytosol]
Histidine catabolism (Bos taurus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Bos taurus)
ADP [cytosol]
Metabolism of carbohydrates (Bos taurus)
Formation of xylulose-5-phosphate (Bos taurus)
XYLB phosphorylates D-xylulose (Bos taurus)
ADP [cytosol]
Fructose metabolism (Bos taurus)
Fructose catabolism (Bos taurus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Bos taurus)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Bos taurus)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Bos taurus)
ADP [cytosol]
Galactose catabolism (Bos taurus)
GALK1 phosphorylates Gal to Gal1P (Bos taurus)
ADP [cytosol]
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Bos taurus)
ADP [cytosol]
Glycolysis (Bos taurus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Bos taurus)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Bos taurus)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Bos taurus)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Bos taurus)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Bos taurus)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Bos taurus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Bos taurus)
ADP [cytosol]
Glycogen metabolism (Bos taurus)
Glycogen breakdown (glycogenolysis) (Bos taurus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Bos taurus)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Bos taurus)
ADP [cytosol]
Glycosaminoglycan metabolism (Bos taurus)
Transport and synthesis of PAPS (Bos taurus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Bos taurus)
ADP [cytosol]
Pentose phosphate pathway (Bos taurus)
RBKS phosphorylates ribose to R5P (Bos taurus)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Bos taurus)
ADP [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Arachidonic acid metabolism (Bos taurus)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Bos taurus)
ALOX5 is phosphorylated by MAPKAP2 (Bos taurus)
ADP [cytosol]
Carnitine metabolism (Bos taurus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Bos taurus)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Bos taurus)
ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Bos taurus)
ADP [cytosol]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Recycling of bile acids and salts (Bos taurus)
ABCB11 transports bile salts from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
ABCB11 transports bile salts from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
Cholesterol biosynthesis (Bos taurus)
MVD decarboxylates MVA5PP to IPPP (Bos taurus)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Bos taurus)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Bos taurus)
ADP [cytosol]
Phospholipid metabolism (Bos taurus)
Glycerophospholipid biosynthesis (Bos taurus)
Synthesis of PC (Bos taurus)
Casein kinase II phosphorylates STARD10 (Bos taurus)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Bos taurus)
ADP [cytosol]
Synthesis of PE (Bos taurus)
ETA is phosphorylated to PETA by CHK/ETNK (Bos taurus)
ADP [cytosol]
PI Metabolism (Bos taurus)
Synthesis of PIPs at the ER membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Bos taurus)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Bos taurus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Bos taurus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Bos taurus)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Bos taurus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Bos taurus)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Bos taurus)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Bos taurus)
BMX phosphorylates RUFY1 (Bos taurus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Bos taurus)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Bos taurus)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Bos taurus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
ADP [cytosol]
Sphingolipid metabolism (Bos taurus)
Glycosphingolipid metabolism (Bos taurus)
Glycosphingolipid biosynthesis (Bos taurus)
CERK phosphorylates CERA to form C1P (Bos taurus)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Bos taurus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Bos taurus)
ADP [cytosol]
CSNK1G2 phosphorylates p-CERT1-2 (Bos taurus)
ADP [cytosol]
PRKD1,2,3 phosphorylates CERT1-2 (Bos taurus)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Bos taurus)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Bos taurus)
ADP [cytosol]
Triglyceride metabolism (Bos taurus)
Triglyceride biosynthesis (Bos taurus)
Conversion of Glycerol to Glycerol-3-phosphate (Bos taurus)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Bos taurus)
eNOS activation (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
ADP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Bos taurus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Bos taurus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Bos taurus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Bos taurus)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Bos taurus)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Bos taurus)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Bos taurus)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Bos taurus)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Bos taurus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Bos taurus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Bos taurus)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Bos taurus)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Bos taurus)
ADP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Bos taurus)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Bos taurus)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Bos taurus)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Bos taurus)
ADP [cytosol]
Pyrimidine biosynthesis (Bos taurus)
CAD hexamer transforms L-Gln to CAP (Bos taurus)
ADP [cytosol]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Bos taurus)
ADP [cytosol]
Pyrimidine catabolism (Bos taurus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Bos taurus)
ADP [cytosol]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Bos taurus)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Bos taurus)
ADP [cytosol]
Pyrimidine salvage (Bos taurus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Bos taurus)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Bos taurus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Bos taurus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Bos taurus)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Bos taurus)
ADP [cytosol]
Metabolism of porphyrins (Bos taurus)
Heme biosynthesis (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
Heme degradation (Bos taurus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Bos taurus)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Bos taurus)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Transport of RCbl within the body (Bos taurus)
ABCC1 transports cytosolic RCbl to extracellular region (Bos taurus)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Bos taurus)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Bos taurus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Bos taurus)
ADP [cytosol]
Metabolism of folate and pterines (Bos taurus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Bos taurus)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Bos taurus)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Bos taurus)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Bos taurus)
ADP [cytosol]
Nicotinate metabolism (Bos taurus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Bos taurus)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Bos taurus)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Bos taurus)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Bos taurus)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Bos taurus)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Bos taurus)
RFK:Mg2+ phosphorylates RIB (Bos taurus)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Bos taurus)
Coenzyme A biosynthesis (Bos taurus)
COASY phosphorylates DP-CoA (Bos taurus)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Bos taurus)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Bos taurus)
ADP [cytosol]
PANK2 phosphorylates PanK (Bos taurus)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Bos taurus)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Bos taurus)
2xPDKX:2xZn2+ phosphorylates PDX (Bos taurus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Bos taurus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Bos taurus)
ADP [cytosol]
Metabolism of RNA (Bos taurus)
Nonsense-Mediated Decay (NMD) (Bos taurus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Bos taurus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Bos taurus)
MK2 phosphorylates BRF1 (Bos taurus)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Bos taurus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Bos taurus)
ADP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
Synthesis of substrates in N-glycan biosythesis (Bos taurus)
GDP-fucose biosynthesis (Bos taurus)
FUK phosphorylates beta-Fuc to Fuc1P (Bos taurus)
ADP [cytosol]
Sialic acid metabolism (Bos taurus)
GNE phosphorylates ManNAc to ManNAc-6-P (Bos taurus)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Bos taurus)
MVD decarboxylates MVA5PP to IPPP (Bos taurus)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Bos taurus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Bos taurus)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Bos taurus)
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
ADP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Bos taurus)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)
FN3KRP phosphorylates PsiAm, RibAm (Bos taurus)
ADP [cytosol]
Protein folding (Bos taurus)
Chaperonin-mediated protein folding (Bos taurus)
Association of TriC/CCT with target proteins during biosynthesis (Bos taurus)
Association of CCT/TriC with sphingosine kinase 1 (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Bos taurus)
ATP binds G-protein beta associated TRiC/CCT (Bos taurus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Bos taurus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
CK2 phosphorylates PDCL (Bos taurus)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Bos taurus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Bos taurus)
GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Bos taurus)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Bos taurus)
GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Bos taurus)
GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Bos taurus)
GNB5:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Surfactant metabolism (Bos taurus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Bos taurus)
ADP [cytosol]
Translation (Bos taurus)
Eukaryotic Translation Initiation (Bos taurus)
Cap-dependent Translation Initiation (Bos taurus)
Ribosomal scanning and start codon recognition (Bos taurus)
Ribosomal scanning (Bos taurus)
ADP [cytosol]
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Ion homeostasis (Bos taurus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)
ADP [cytosol]
PRKACA phosphorylates PLN (Bos taurus)
ADP [cytosol]
Smooth Muscle Contraction (Bos taurus)
ATP Hydrolysis By Myosin (Bos taurus)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Bos taurus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Bos taurus)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Bos taurus)
ADP [cytosol]
Release Of ADP From Myosin (Bos taurus)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Bos taurus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Bos taurus)
ADP [cytosol]
Striated Muscle Contraction (Bos taurus)
ATP Hydrolysis By Myosin (Bos taurus)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
ADP Bound Myosin Complex [cytosol] (Bos taurus)
ADP [cytosol]
Release Of ADP From Myosin (Bos taurus)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Bos taurus)
ADP Bound Myosin Complex [cytosol] (Bos taurus)
ADP [cytosol]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
Activation of NMDA receptors and postsynaptic events (Bos taurus)
Post NMDA receptor activation events (Bos taurus)
Activation of RAC1 downstream of NMDARs (Bos taurus)
CaMKK autophosphorylates in the cytosol (Bos taurus)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Bos taurus)
Trafficking of AMPA receptors (Bos taurus)
Trafficking of GluR1-containing AMPA receptors (Bos taurus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Bos taurus)
Endocytosis of Ca impermeable AMPA receptors (Bos taurus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Bos taurus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Bos taurus)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Bos taurus)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Bos taurus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Bos taurus)
ADP [cytosol]
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
Caspase activation via Dependence Receptors in the absence of ligand (Bos taurus)
Activation of caspase-3 (Bos taurus)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Bos taurus)
Activation of BH3-only proteins (Bos taurus)
Activation of BIM and translocation to mitochondria (Bos taurus)
Phosphorylation of BIM by JNK (Bos taurus)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Bos taurus)
Phosphorylation of DLC2 by MAPK8 (Bos taurus)
ADP [cytosol]
Apoptotic factor-mediated response (Bos taurus)
Cytochrome c-mediated apoptotic response (Bos taurus)
Activation of caspases through apoptosome-mediated cleavage (Bos taurus)
Cleavage of Procaspase-3 by the apoptosome (Bos taurus)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Bos taurus)
ADP [cytosol]
Formation of apoptosome (Bos taurus)
CYCS binds to APAF1 (Bos taurus)
ADP [cytosol]
APAF1:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Bos taurus)
ADP [cytosol]
Regulation of the apoptosome activity (Bos taurus)
APAF1 binds AVEN (Bos taurus)
APAF1:ADP [cytosol] (Bos taurus)
ADP [cytosol]
APAF1:AVEN [cytosol] (Bos taurus)
APAF1:ADP [cytosol] (Bos taurus)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Bos taurus)
ADP [cytosol]
Regulated Necrosis (Bos taurus)
RIPK1-mediated regulated necrosis (Bos taurus)
RIPK1 is phosphorylated (Bos taurus)
ADP [cytosol]
RIPK3 is phosphorylated (Bos taurus)
ADP [cytosol]
RIPK3 phosphorylates MLKL (Bos taurus)
ADP [cytosol]
Protein localization (Bos taurus)
Peroxisomal protein import (Bos taurus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Bos taurus)
ADP [cytosol]
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
The canonical retinoid cycle in rods (twilight vision) (Bos taurus)
ABCA4 mediates atRAL transport (Bos taurus)
ADP [cytosol]
The phototransduction cascade (Bos taurus)
Inactivation, recovery and regulation of the phototransduction cascade (Bos taurus)
GRK1,4,7 phosphorylate MII to p-MII (Bos taurus)
ADP [cytosol]
Signal Transduction (Bos taurus)
Death Receptor Signaling (Bos taurus)
TNF signaling (Bos taurus)
Regulation of TNFR1 signaling (Bos taurus)
CHUK, IKBKB phosphorylate CYLD at S418 (Bos taurus)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Bos taurus)
ADP [cytosol]
MAPKAPK2 phosphorylates RIPK1 at S320 (Bos taurus)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Bos taurus)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Bos taurus)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Bos taurus)
Cell death signalling via NRAGE, NRIF and NADE (Bos taurus)
NRAGE signals death through JNK (Bos taurus)
GTP-bound RAC contributes to JNK activation (Bos taurus)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Bos taurus)
ADP [cytosol]
p75NTR signals via NF-kB (Bos taurus)
NF-kB is activated and signals survival (Bos taurus)
IKKbeta is activated (Bos taurus)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Bos taurus)
ADP [cytosol]
Integrin signaling (Bos taurus)
Autophosphorylation of PTK2 at Y397 (Bos taurus)
ADP [cytosol]
Autophosphorylation of SRC (Bos taurus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Bos taurus)
ADP [cytosol]
SYK activation by SRC (Bos taurus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
ADP [cytosol]
Intracellular signaling by second messengers (Bos taurus)
DAG and IP3 signaling (Bos taurus)
CaM pathway (Bos taurus)
Calmodulin induced events (Bos taurus)
PKC phosphorylates GRK2 (Bos taurus)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Bos taurus)
ADP [cytosol]
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Bos taurus)
ADP [cytosol]
MAPKs phosphorylate PP2A (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
PTEN Regulation (Bos taurus)
Regulation of PTEN gene transcription (Bos taurus)
mTORC1 phosphorylates MAF1 (Bos taurus)
ADP [cytosol]
Regulation of PTEN stability and activity (Bos taurus)
Casein kinase II phosphorylates PTEN (Bos taurus)
ADP [cytosol]
FRK phosphorylates PTEN (Bos taurus)
ADP [cytosol]
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF-independent MAPK1/3 activation (Bos taurus)
MAPK1 (ERK2) activation (Bos taurus)
MAP2K2 phosphorylates MAPK1 (Bos taurus)
ADP [cytosol]
MAPK3 (ERK1) activation (Bos taurus)
Inactivation of MAP2K1 by CDK1 (Bos taurus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Bos taurus)
ADP [cytosol]
RAF/MAP kinase cascade (Bos taurus)
MAP2K and MAPK activation (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Bos taurus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Bos taurus)
ADP [cytosol]
Negative regulation of MAPK pathway (Bos taurus)
MAPK12 phosphorylates PTPN3 (Bos taurus)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Bos taurus)
Activated MAPKs phosphorylate BRAF (Bos taurus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
ADP [cytosol]
RAF activation (Bos taurus)
MARK3 phosphorylates KSR1 (Bos taurus)
ADP [cytosol]
Phosphorylation of RAF (Bos taurus)
ADP [cytosol]
RAS processing (Bos taurus)
KRAS4B is phosphorylated on serine 181 (Bos taurus)
ADP [cytosol]
MAPK6/MAPK4 signaling (Bos taurus)
Autophosphorylation of PAK1,2,3 (Bos taurus)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Bos taurus)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Bos taurus)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Bos taurus)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Bos taurus)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Bos taurus)
ADP [cytosol]
MTOR signalling (Bos taurus)
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Bos taurus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Bos taurus)
Phosphorylation of TSC2 by PKB (Bos taurus)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Bos taurus)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Bos taurus)
ADP [cytosol]
mTORC1-mediated signalling (Bos taurus)
Phosphorylation and activation of eIF4B by activated S6K1 (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Bos taurus)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Bos taurus)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Bos taurus)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
ADP [cytosol]
Signaling by Erythropoietin (Bos taurus)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Bos taurus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Bos taurus)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Bos taurus)
ADP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)
ADP [cytosol]
Opioid Signalling (Bos taurus)
DARPP-32 events (Bos taurus)
PKA phosphorylates DARPP-32 on Thr34 (Bos taurus)
ADP [cytosol]
PKA phosphorylates PDE4B (Bos taurus)
ADP [cytosol]
G-protein mediated events (Bos taurus)
PLC beta mediated events (Bos taurus)
Ca-dependent events (Bos taurus)
CaM pathway (Bos taurus)
Calmodulin induced events (Bos taurus)
PKC phosphorylates GRK2 (Bos taurus)
ADP [cytosol]
phospho-PLA2 pathway (Bos taurus)
Phosphorylation of cPLA2 by ERK-2 (Bos taurus)
ADP [cytosol]
G alpha (q) signalling events (Bos taurus)
Effects of PIP2 hydrolysis (Bos taurus)
DAG kinase produces phosphatidic acid from DAG (Bos taurus)
ADP [cytosol]
G alpha (s) signalling events (Bos taurus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Bos taurus)
ADP [cytosol]
G-protein beta:gamma signalling (Bos taurus)
G beta:gamma signalling through PI3Kgamma (Bos taurus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Signaling by Hedgehog (Bos taurus)
Hedgehog 'off' state (Bos taurus)
GLI3 is processed to GLI3R by the proteasome (Bos taurus)
CK1 phosphorylates p-GLI3 (Bos taurus)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Bos taurus)
ADP [cytosol]
PKA phosphorylates GLI3 (Bos taurus)
ADP [cytosol]
Hedgehog ligand biogenesis (Bos taurus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Bos taurus)
ADP [cytosol]
Signaling by Hippo (Bos taurus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Bos taurus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Bos taurus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Bos taurus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Bos taurus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Bos taurus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Bos taurus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Bos taurus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Bos taurus)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Bos taurus)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Bos taurus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Bos taurus)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Bos taurus)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Bos taurus)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Bos taurus)
Signaling by PTK6 (Bos taurus)
ERBB2 Activates PTK6 Signaling (Bos taurus)
ERBB2 promotes PTK6 autophosphorylation (Bos taurus)
ADP [cytosol]
PTK6 Activates STAT3 (Bos taurus)
PTK6 phosphorylates STAP2 (Bos taurus)
ADP [cytosol]
PTK6 phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
PTK6 Down-Regulation (Bos taurus)
SRMS phosphorylates PTK6 (Bos taurus)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Bos taurus)
PTK6 phosphorylates CDKN1B (Bos taurus)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Bos taurus)
PTK6 phosphorylates ARHGAP35 (Bos taurus)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Bos taurus)
ADP [cytosol]
PTK6 phosphorylates PXN (Bos taurus)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Bos taurus)
PTK6 phosphorylates ARAP1 (Bos taurus)
ADP [cytosol]
PTK6 phosphorylates CBL (Bos taurus)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Bos taurus)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Bos taurus)
EGFR phosphorylates GPNMB (Bos taurus)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Bos taurus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Bos taurus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Bos taurus)
ADP [cytosol]
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
ESR-associated SRC autophosphorylates (Bos taurus)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Bos taurus)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Bos taurus)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by ALK (Bos taurus)
ALK autophosphorylation (Bos taurus)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Bos taurus)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Bos taurus)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Bos taurus)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Bos taurus)
ADP [cytosol]
Signaling by EGFR (Bos taurus)
EGFR autophosphorylation (Bos taurus)
ADP [cytosol]
EGFR downregulation (Bos taurus)
EGFR phosphorylates EPS15 (Bos taurus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Bos taurus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Bos taurus)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Bos taurus)
EGFR activates PLC-gamma1 by phosphorylation (Bos taurus)
ADP [cytosol]
GAB1 signalosome (Bos taurus)
GAB1 phosphorylation by EGFR kinase (Bos taurus)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Bos taurus)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Bos taurus)
ADP [cytosol]
SHC1 events in EGFR signaling (Bos taurus)
SHC1 phosphorylation by phosphorylated EGFR (Bos taurus)
ADP [cytosol]
Signaling by ERBB2 (Bos taurus)
ERBB2 Activates PTK6 Signaling (Bos taurus)
ERBB2 promotes PTK6 autophosphorylation (Bos taurus)
ADP [cytosol]
PI3K events in ERBB2 signaling (Bos taurus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Bos taurus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Bos taurus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Bos taurus)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Bos taurus)
SHC1 phosphorylation by ERBB2 heterodimers (Bos taurus)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Bos taurus)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Bos taurus)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Bos taurus)
ADP [cytosol]
Signaling by ERBB4 (Bos taurus)
PI3K events in ERBB4 signaling (Bos taurus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Bos taurus)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Bos taurus)
Phosphorylation of SHC1 by ERBB4 homodimers (Bos taurus)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Bos taurus)
ADP [cytosol]
Signaling by FGFR (Bos taurus)
Signaling by FGFR1 (Bos taurus)
Downstream signaling of activated FGFR1 (Bos taurus)
FRS-mediated FGFR1 signaling (Bos taurus)
Activated FGFR1 phosphorylates FRS2 (Bos taurus)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Bos taurus)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Bos taurus)
ADP [cytosol]
PI-3K cascade:FGFR1 (Bos taurus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Bos taurus)
Activated FGFR1 phosphorylates PLCG1 (Bos taurus)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Bos taurus)
Activated FGFR1 phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
FGFR1 ligand binding and activation (Bos taurus)
FGFR1b ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR1b (Bos taurus)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Bos taurus)
ADP [cytosol]
FGFR1c ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR1c (Bos taurus)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Bos taurus)
ADP [cytosol]
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
ADP [cytosol]
Signaling by FGFR2 (Bos taurus)
Downstream signaling of activated FGFR2 (Bos taurus)
FRS-mediated FGFR2 signaling (Bos taurus)
Activated FGFR2 phosphorylates FRS2 (Bos taurus)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Bos taurus)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Bos taurus)
ADP [cytosol]
PI-3K cascade:FGFR2 (Bos taurus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Bos taurus)
Activated FGFR2 phosphorylates PLCG1 (Bos taurus)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Bos taurus)
Activated FGFR2 phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
FGFR2 ligand binding and activation (Bos taurus)
FGFR2b ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR2b (Bos taurus)
ADP [cytosol]
FGFR2c ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR2c (Bos taurus)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Bos taurus)
ADP [cytosol]
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
ADP [cytosol]
Signaling by FGFR3 (Bos taurus)
Downstream signaling of activated FGFR3 (Bos taurus)
FRS-mediated FGFR3 signaling (Bos taurus)
Activated FGFR3 phosphorylates FRS2 (Bos taurus)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Bos taurus)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Bos taurus)
ADP [cytosol]
PI-3K cascade:FGFR3 (Bos taurus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Bos taurus)
Activated FGFR3 phosphorylates PLCG1 (Bos taurus)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Bos taurus)
Activated FGFR3 phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
FGFR3 ligand binding and activation (Bos taurus)
FGFR3b ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR3b (Bos taurus)
ADP [cytosol]
FGFR3c ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR3c (Bos taurus)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Bos taurus)
ADP [cytosol]
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
ADP [cytosol]
Signaling by FGFR4 (Bos taurus)
Downstream signaling of activated FGFR4 (Bos taurus)
FRS-mediated FGFR4 signaling (Bos taurus)
Activated FGFR4 phosphorylates FRS2 (Bos taurus)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Bos taurus)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Bos taurus)
ADP [cytosol]
PI-3K cascade:FGFR4 (Bos taurus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Bos taurus)
Activated FGFR4 phosphorylates PLCG1 (Bos taurus)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Bos taurus)
Activated FGFR4 phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
FGFR4 ligand binding and activation (Bos taurus)
Autocatalytic phosphorylation of FGFR4 (Bos taurus)
ADP [cytosol]
betaKlotho-mediated ligand binding (Bos taurus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Bos taurus)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Bos taurus)
ADP [cytosol]
Spry regulation of FGF signaling (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
ADP [cytosol]
Signaling by Insulin receptor (Bos taurus)
Autophosphorylation of insulin receptor (Bos taurus)
ADP [cytosol]
Insulin receptor signalling cascade (Bos taurus)
IRS activation (Bos taurus)
Phosphorylation of IRS (Bos taurus)
ADP [cytosol]
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
Activation of AKT2 (Bos taurus)
PDPK1 phosphorylates AKT2 (Bos taurus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation of SHC1 (Bos taurus)
ADP [cytosol]
Signal attenuation (Bos taurus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Bos taurus)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Bos taurus)
ADP [cytosol]
Signaling by MET (Bos taurus)
MET Receptor Activation (Bos taurus)
MET dimers autophosphorylate (Bos taurus)
ADP [cytosol]
MET activates PI3K/AKT signaling (Bos taurus)
MET bound PI3K generates PIP3 (Bos taurus)
ADP [cytosol]
MET phosphorylates GAB1 (Bos taurus)
ADP [cytosol]
MET activates RAS signaling (Bos taurus)
MET phosphorylates SHC1-2 (Bos taurus)
ADP [cytosol]
MET activates STAT3 (Bos taurus)
MET phosphorylates STAT3 (Bos taurus)
ADP [cytosol]
MET promotes cell motility (Bos taurus)
MET activates PTK2 signaling (Bos taurus)
MET phosphorylates PTK2 (Bos taurus)
ADP [cytosol]
PTK2 autophosphorylates (Bos taurus)
ADP [cytosol]
SRC phosphorylates PTK2 (Bos taurus)
ADP [cytosol]
Negative regulation of MET activity (Bos taurus)
MET phosphorylates CBL (Bos taurus)
ADP [cytosol]
Signaling by MST1 (Bos taurus)
MST1R autophosphorylates (Bos taurus)
ADP [cytosol]
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
PI3K/AKT activation (Bos taurus)
PI3K produces PIP3 and other phosphatidyl inositides (Bos taurus)
ADP [cytosol]
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
ARMS-mediated activation (Bos taurus)
ARMS is phosphorylated by active TrkA receptor (Bos taurus)
ADP [cytosol]
Frs2-mediated activation (Bos taurus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Bos taurus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Bos taurus)
ADP [cytosol]
Signalling to RAS (Bos taurus)
p38MAPK events (Bos taurus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Bos taurus)
Activated NTRK3 signals through PI3K (Bos taurus)
Activated NTRK3 promotes SRC autophosphorylation (Bos taurus)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Bos taurus)
NTRK3 dimers trans-autophosphorylate (Bos taurus)
ADP [cytosol]
Signaling by PDGF (Bos taurus)
Autophosphorylation of PDGF alpha receptors (Bos taurus)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Bos taurus)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Bos taurus)
ADP [cytosol]
Downstream signal transduction (Bos taurus)
Activation of Src (Bos taurus)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Bos taurus)
ADP [cytosol]
Signaling by SCF-KIT (Bos taurus)
Autophosphorylation of KIT (Bos taurus)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Bos taurus)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Bos taurus)
ADP [cytosol]
Phosphorylation of JAK2 (Bos taurus)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Bos taurus)
ADP [cytosol]
Phosphorylation of STATs (Bos taurus)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Bos taurus)
ADP [cytosol]
Regulation of KIT signaling (Bos taurus)
Phosphorylation of APS (Bos taurus)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Bos taurus)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Bos taurus)
IGF1,2:IGF1R autophosphorylates (Bos taurus)
ADP [cytosol]
IGF1R signaling cascade (Bos taurus)
IRS-related events triggered by IGF1R (Bos taurus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Bos taurus)
ADP [cytosol]
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
Activation of AKT2 (Bos taurus)
PDPK1 phosphorylates AKT2 (Bos taurus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
SHC-related events triggered by IGF1R (Bos taurus)
IGF1R phosphorylates SHC1 (Bos taurus)
ADP [cytosol]
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
AXL autophosphorylates on Y779 and Y821 (Bos taurus)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Bos taurus)
ADP [cytosol]
FYN autophosphorylates (Bos taurus)
ADP [cytosol]
FYN phosphorylates PAK2 (Bos taurus)
ADP [cytosol]
PAK2 autophorylates (Bos taurus)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Bos taurus)
ADP [cytosol]
PTK2 autophosphorylates (Bos taurus)
ADP [cytosol]
Phosphorylation of SRC-1 (Bos taurus)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Bos taurus)
ADP [cytosol]
SRC-1 phosphorylates SHB (Bos taurus)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Bos taurus)
ADP [cytosol]
Src kinases phosphorylate VAV (Bos taurus)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
ADP [cytosol]
VEGFR2 autophosphorylates (Bos taurus)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Bos taurus)
PDK1 phosphorylates PKC (Bos taurus)
ADP [cytosol]
PKC autophosphorylates (Bos taurus)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Bos taurus)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Bos taurus)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
ADP [cytosol]
PAK1-3 autophosphorylates (Bos taurus)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Bos taurus)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Bos taurus)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Bos taurus)
ADP [cytosol]
p38 MAPK activation by VEGFR (Bos taurus)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
RHOBTB3 ATPase cycle (Bos taurus)
RHOBTB3 hydrolyzes ATP (Bos taurus)
RHOBTB3:ADP [trans-Golgi network membrane] (Bos taurus)
ADP [cytosol]
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate Formins (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Bos taurus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Bos taurus)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Bos taurus)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Bos taurus)
ADP [cytosol]
PKC phosphorylates NCF1 (Bos taurus)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Bos taurus)
ABL phosphorylates WAVEs (Bos taurus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Bos taurus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Bos taurus)
Actin:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Detachment of WASP/WAVE (Bos taurus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Bos taurus)
Actin:ADP [cytosol] (Bos taurus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Bos taurus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
ADP [cytosol]
RHO GTPases activate PAKs (Bos taurus)
Autophosphorylation of PAK1,2,3 (Bos taurus)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Bos taurus)
ADP [cytosol]
PAK1 phosphorylates FLNA (Bos taurus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Bos taurus)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Bos taurus)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Bos taurus)
ADP [cytosol]
RHO GTPases activate PKNs (Bos taurus)
PDPK1 phosphorylates PKN1,2,3 (Bos taurus)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Bos taurus)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Bos taurus)
ADP [cytosol]
Signaling by TGFB family members (Bos taurus)
Signaling by Activin (Bos taurus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Bos taurus)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Bos taurus)
ADP [cytosol]
Signaling by BMP (Bos taurus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Bos taurus)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Bos taurus)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Bos taurus)
TGF-beta receptor signaling activates SMADs (Bos taurus)
Activated type I receptor phosphorylates SMAD2/3 directly (Bos taurus)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Bos taurus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Bos taurus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Bos taurus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Bos taurus)
ADP [cytosol]
Signaling by WNT (Bos taurus)
Beta-catenin independent WNT signaling (Bos taurus)
Ca2+ pathway (Bos taurus)
Activation of NLK (Bos taurus)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Bos taurus)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Bos taurus)
ADP [cytosol]
PCP/CE pathway (Bos taurus)
WNT5A-dependent internalization of FZD4 (Bos taurus)
DVL2 is phosphorylated by PKC (Bos taurus)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Bos taurus)
AXIN is phosphorylated in the destruction complex (Bos taurus)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Bos taurus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Bos taurus)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Bos taurus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Bos taurus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Bos taurus)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Bos taurus)
ADP [cytosol]
TCF dependent signaling in response to WNT (Bos taurus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Bos taurus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Bos taurus)
ADP [cytosol]
WNT mediated activation of DVL (Bos taurus)
CSNK2-mediated phosphorylation of DVL (Bos taurus)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Bos taurus)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Bos taurus)
ADP [cytosol]
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
ABC transporters in lipid homeostasis (Bos taurus)
ABCA12 transports lipids from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Bos taurus)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Bos taurus)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Bos taurus)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCA4 mediates atRAL transport (Bos taurus)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Bos taurus)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Bos taurus)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
HCO3- transport through ion channel (Bos taurus)
ADP [cytosol]
Mitochondrial ABC transporters (Bos taurus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Bos taurus)
ADP [cytosol]
The ABCC family mediates organic anion transport (Bos taurus)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Bos taurus)
ADP [cytosol]
Aquaporin-mediated transport (Bos taurus)
Vasopressin regulates renal water homeostasis via Aquaporins (Bos taurus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Bos taurus)
ADP [cytosol]
Ion channel transport (Bos taurus)
Ion transport by P-type ATPases (Bos taurus)
ATP12A:ATP4B exchanges K+ for H+ (Bos taurus)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Bos taurus)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Bos taurus)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Bos taurus)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Bos taurus)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Bos taurus)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Bos taurus)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Bos taurus)
ADP [cytosol]
Iron uptake and transport (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
ADP [cytosol]
Transferrin endocytosis and recycling (Bos taurus)
Acidification of Tf:TfR1 containing endosome (Bos taurus)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Bos taurus)
Plasma lipoprotein assembly (Bos taurus)
HDL assembly (Bos taurus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Bos taurus)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Bos taurus)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Bos taurus)
ADP [cytosol]
Plasma lipoprotein remodeling (Bos taurus)
HDL remodeling (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
ADP [cytosol]
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Bos taurus)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Bos taurus)
ADP [cytosol]
Vesicle-mediated transport (Bos taurus)
Membrane Trafficking (Bos taurus)
Clathrin-mediated endocytosis (Bos taurus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Bos taurus)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Bos taurus)
ADBRK1,2 phosphorylate AVPR2 (Bos taurus)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Bos taurus)
clathrin:HSPA8:ADP [cytosol] (Bos taurus)
HSPA8:ADP [cytosol] (Bos taurus)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Bos taurus)
ADP [cytosol]
ER to Golgi Anterograde Transport (Bos taurus)
COPI-mediated anterograde transport (Bos taurus)
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
ADP [cytosol]
COPII-mediated vesicle transport (Bos taurus)
CSNK1D phosphorylates SEC23 (Bos taurus)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Bos taurus)
ESCRT Disassembly (Bos taurus)
ADP [cytosol]
Gap junction trafficking and regulation (Bos taurus)
Regulation of gap junction activity (Bos taurus)
Phosphorylation of Cx43 by c-src (Bos taurus)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Bos taurus)
Golgi-to-ER retrograde transport (Bos taurus)
COPI-independent Golgi-to-ER retrograde traffic (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
ADP [cytosol]
Intra-Golgi traffic (Bos taurus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Bos taurus)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Bos taurus)
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Bos taurus)
RHOBTB3:ADP [trans-Golgi network membrane] (Bos taurus)
ADP [cytosol]
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Bos taurus)
ADP [cytosol]
Rab regulation of trafficking (Bos taurus)
RAB GEFs exchange GTP for GDP on RABs (Bos taurus)
p-ULK1 phosphorylates DENND3 (Bos taurus)
ADP [cytosol]
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
AMPK (complex) phosphorylates ULK1 (complex) (Caenorhabditis elegans)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Caenorhabditis elegans)
ADP [cytosol]
Selective autophagy (Caenorhabditis elegans)
Mitophagy (Caenorhabditis elegans)
Receptor Mediated Mitophagy (Caenorhabditis elegans)
FUNDC1 is phosphorylated by CK2 (Caenorhabditis elegans)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Caenorhabditis elegans)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Caenorhabditis elegans)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Caenorhabditis elegans)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Caenorhabditis elegans)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Caenorhabditis elegans)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
ADP [cytosol]
Cell Cycle (Caenorhabditis elegans)
Cell Cycle Checkpoints (Caenorhabditis elegans)
G2/M Checkpoints (Caenorhabditis elegans)
G2/M DNA replication checkpoint (Caenorhabditis elegans)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Caenorhabditis elegans)
ADP [cytosol]
Cell Cycle, Mitotic (Caenorhabditis elegans)
M Phase (Caenorhabditis elegans)
Mitotic Prometaphase (Caenorhabditis elegans)
EML4 and NUDC in mitotic spindle formation (Caenorhabditis elegans)
NEK6 and NEK7 phosphorylate EML4 (Caenorhabditis elegans)
ADP [cytosol]
PLK1 phosphorylates NUDC (Caenorhabditis elegans)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Caenorhabditis elegans)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Caenorhabditis elegans)
ADP [cytosol]
Mitotic Prophase (Caenorhabditis elegans)
Golgi Cisternae Pericentriolar Stack Reorganization (Caenorhabditis elegans)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Caenorhabditis elegans)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Caenorhabditis elegans)
ADP [cytosol]
Nuclear Envelope Breakdown (Caenorhabditis elegans)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Caenorhabditis elegans)
CDK1:CCNB phosphorylates NEK9 (Caenorhabditis elegans)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Caenorhabditis elegans)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Caenorhabditis elegans)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Caenorhabditis elegans)
G1/S Transition (Caenorhabditis elegans)
Cyclin E associated events during G1/S transition (Caenorhabditis elegans)
AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)
ADP [cytosol]
Mitotic G2-G2/M phases (Caenorhabditis elegans)
G2/M Transition (Caenorhabditis elegans)
Cyclin A/B1/B2 associated events during G2/M transition (Caenorhabditis elegans)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Caenorhabditis elegans)
ADP [cytosol]
Polo-like kinase mediated events (Caenorhabditis elegans)
Activation of Cdc25C (Caenorhabditis elegans)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Caenorhabditis elegans)
CDK1 phosphorylates BORA (Caenorhabditis elegans)
ADP [cytosol]
PLK1 phosphorylates BORA (Caenorhabditis elegans)
ADP [cytosol]
S Phase (Caenorhabditis elegans)
Cyclin A:Cdk2-associated events at S phase entry (Caenorhabditis elegans)
AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)
ADP [cytosol]
Cell-Cell communication (Caenorhabditis elegans)
Nephrin family interactions (Caenorhabditis elegans)
Phosphorylation of nephrin by FYN (Caenorhabditis elegans)
ADP [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Cellular Senescence (Caenorhabditis elegans)
Oxidative Stress Induced Senescence (Caenorhabditis elegans)
MAP3K5 phosphorylates MKK3 and MKK6 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Cellular response to chemical stress (Caenorhabditis elegans)
KEAP1-NFE2L2 pathway (Caenorhabditis elegans)
PRKCI phosphorylates NFE2L2 (Caenorhabditis elegans)
ADP [cytosol]
Cellular response to heat stress (Caenorhabditis elegans)
Regulation of HSF1-mediated heat shock response (Caenorhabditis elegans)
Constitutive phosphorylation by pERK1/2 (Caenorhabditis elegans)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Caenorhabditis elegans)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Caenorhabditis elegans)
ADP [cytosol]
HSP70s:ADP [cytosol] (Caenorhabditis elegans)
HSP13:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA2:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA4:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA5:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA6:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA8:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA9:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Caenorhabditis elegans)
HSP70s:ADP [cytosol] (Caenorhabditis elegans)
HSP13:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA2:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA4:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA5:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA6:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA8:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSPA9:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Caenorhabditis elegans)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Caenorhabditis elegans)
ATP binding to HSP90 triggers conformation change (Caenorhabditis elegans)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Caenorhabditis elegans)
HSP70:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Caenorhabditis elegans)
HSP70:ADP:nascent protein [cytosol] (Caenorhabditis elegans)
HSP70:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
ATP hydrolysis by HSP70 (Caenorhabditis elegans)
HSP40:HSP70:ADP:nascent protein [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Caenorhabditis elegans)
HSP40:HSP70:ADP:nascent protein [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Caenorhabditis elegans)
HSP70:ADP:nascent protein [cytosol] (Caenorhabditis elegans)
HSP70:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Unfolded Protein Response (UPR) (Caenorhabditis elegans)
IRE1alpha activates chaperones (Caenorhabditis elegans)
IRE1 dimer autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
PERK regulates gene expression (Caenorhabditis elegans)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Caenorhabditis elegans)
ADP [cytosol]
Developmental Biology (Caenorhabditis elegans)
Nervous system development (Caenorhabditis elegans)
Axon guidance (Caenorhabditis elegans)
EPH-Ephrin signaling (Caenorhabditis elegans)
EPH receptors autophosphorylate (Caenorhabditis elegans)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Caenorhabditis elegans)
SFKs phosphorylate VAV2,3 (Caenorhabditis elegans)
ADP [cytosol]
EPHB-mediated forward signaling (Caenorhabditis elegans)
EPHB phosphorylates TIAM1 (Caenorhabditis elegans)
ADP [cytosol]
PAK1 autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Caenorhabditis elegans)
ADP [cytosol]
Ephrin signaling (Caenorhabditis elegans)
PAKs autophosphorylate (Caenorhabditis elegans)
ADP [cytosol]
PAKs phosphorylate MLC (Caenorhabditis elegans)
ADP [cytosol]
L1CAM interactions (Caenorhabditis elegans)
Recycling pathway of L1 (Caenorhabditis elegans)
Phosphorylation of L1 by ERK (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of L1 by SRC (Caenorhabditis elegans)
ADP [cytosol]
Signal transduction by L1 (Caenorhabditis elegans)
Interaction of PAK1 with Rac1-GTP (Caenorhabditis elegans)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Caenorhabditis elegans)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of L1 by CK-II (Caenorhabditis elegans)
ADP [cytosol]
Netrin-1 signaling (Caenorhabditis elegans)
DCC mediated attractive signaling (Caenorhabditis elegans)
Phosphorylation of DCC by Fyn (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Caenorhabditis elegans)
ADP [cytosol]
Semaphorin interactions (Caenorhabditis elegans)
CRMPs in Sema3A signaling (Caenorhabditis elegans)
Phosphorylation of CRMPs by Cdk5 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Caenorhabditis elegans)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Caenorhabditis elegans)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Caenorhabditis elegans)
Autophosphorylation of PAK (Caenorhabditis elegans)
ADP [cytosol]
Sema4D in semaphorin signaling (Caenorhabditis elegans)
Sema4D induced cell migration and growth-cone collapse (Caenorhabditis elegans)
SEMA4D interacts with Plexin-B1:ErbB2 (Caenorhabditis elegans)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Caenorhabditis elegans)
SEMA4D interacts with Plexin-B1:Met (Caenorhabditis elegans)
ADP [cytosol]
Drug ADME (Caenorhabditis elegans)
Aspirin ADME (Caenorhabditis elegans)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Caenorhabditis elegans)
ADP [cytosol]
Azathioprine ADME (Caenorhabditis elegans)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Caenorhabditis elegans)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Caenorhabditis elegans)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Caenorhabditis elegans)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Caenorhabditis elegans)
ADP [cytosol]
Ciprofloxacin ADME (Caenorhabditis elegans)
ABCG2 transports Cipro from hepatic cell to extracellular space (Caenorhabditis elegans)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Caenorhabditis elegans)
ADP [cytosol]
Paracetamol ADME (Caenorhabditis elegans)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)
ADP [cytosol]
Ribavirin ADME (Caenorhabditis elegans)
ADK phosphorylates RBV (Caenorhabditis elegans)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Caenorhabditis elegans)
ADP [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
Regulation of TP53 Activity (Caenorhabditis elegans)
Regulation of TP53 Expression and Degradation (Caenorhabditis elegans)
Regulation of TP53 Degradation (Caenorhabditis elegans)
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Caenorhabditis elegans)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Caenorhabditis elegans)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Caenorhabditis elegans)
Regulation of RUNX3 expression and activity (Caenorhabditis elegans)
SRC phosphorylates RUNX3 (Caenorhabditis elegans)
ADP [cytosol]
Hemostasis (Caenorhabditis elegans)
Factors involved in megakaryocyte development and platelet production (Caenorhabditis elegans)
Kinesins (Caenorhabditis elegans)
Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
ADP [cytosol]
Platelet activation, signaling and aggregation (Caenorhabditis elegans)
Effects of PIP2 hydrolysis (Caenorhabditis elegans)
DAG kinase produces phosphatidic acid from DAG (Caenorhabditis elegans)
ADP [cytosol]
GPVI-mediated activation cascade (Caenorhabditis elegans)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Caenorhabditis elegans)
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
ADP [cytosol]
Autophosphorylation of SRC (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
ADP [cytosol]
SYK activation by SRC (Caenorhabditis elegans)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Caenorhabditis elegans)
Disinhibition of SNARE formation (Caenorhabditis elegans)
Phosphorylation of Platelet Sec-1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Caenorhabditis elegans)
ADP [cytosol]
Platelet degranulation (Caenorhabditis elegans)
ABCC4 accumulation of dense granule contents (Caenorhabditis elegans)
ADP [cytosol]
Signal amplification (Caenorhabditis elegans)
ADP signalling through P2Y purinoceptor 1 (Caenorhabditis elegans)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Caenorhabditis elegans)
ADP [cytosol]
Platelet homeostasis (Caenorhabditis elegans)
Platelet sensitization by LDL (Caenorhabditis elegans)
Fgr may phosphorylate p38 MAPK (Caenorhabditis elegans)
ADP [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Caenorhabditis elegans)
Transport of Antigen peptide in to ER (Caenorhabditis elegans)
ADP [cytosol]
Costimulation by the CD28 family (Caenorhabditis elegans)
CD28 co-stimulation (Caenorhabditis elegans)
CD28 dependent PI3K/Akt signaling (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
ADP [cytosol]
Rap1 signalling (Caenorhabditis elegans)
PKA/PKG phosphorylate Rap1GAP2 (Caenorhabditis elegans)
ADP [cytosol]
TCR signaling (Caenorhabditis elegans)
Downstream TCR signaling (Caenorhabditis elegans)
Phosphorylation of PKC theta (Caenorhabditis elegans)
ADP [cytosol]
Cytokine Signaling in Immune system (Caenorhabditis elegans)
Interferon Signaling (Caenorhabditis elegans)
Antiviral mechanism by IFN-stimulated genes (Caenorhabditis elegans)
PKR-mediated signaling (Caenorhabditis elegans)
p-PKR dimer phosphorylates CDK1 (Caenorhabditis elegans)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Caenorhabditis elegans)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Caenorhabditis elegans)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Caenorhabditis elegans)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Caenorhabditis elegans)
ADP [cytosol]
Interferon gamma signaling (Caenorhabditis elegans)
JAK2-activated MAPKs phosphorylate YBX1 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Interleukins (Caenorhabditis elegans)
Interleukin-1 family signaling (Caenorhabditis elegans)
Interleukin-1 signaling (Caenorhabditis elegans)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Caenorhabditis elegans)
ADP [cytosol]
Interleukin-37 signaling (Caenorhabditis elegans)
STAT3 phosphorylation (Caenorhabditis elegans)
ADP [cytosol]
Interleukin-38 signaling (Caenorhabditis elegans)
MAPK8 phosphorylation (Caenorhabditis elegans)
ADP [cytosol]
Interleukin-17 signaling (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Innate Immune System (Caenorhabditis elegans)
C-type lectin receptors (CLRs) (Caenorhabditis elegans)
CD209 (DC-SIGN) signaling (Caenorhabditis elegans)
PAK phosphorylates p21 RAF1 on S338 (Caenorhabditis elegans)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Caenorhabditis elegans)
STING mediated induction of host immune responses (Caenorhabditis elegans)
STAT6-mediated induction of chemokines (Caenorhabditis elegans)
p-S407-STAT6 is phosphorylated at Tyr641 (Caenorhabditis elegans)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Caenorhabditis elegans)
Autophosphorylation of LYN kinase (Caenorhabditis elegans)
ADP [cytosol]
FCERI mediated MAPK activation (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
FCERI mediated NF-kB activation (Caenorhabditis elegans)
Autophosphorylation of PKC-theta (Caenorhabditis elegans)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Caenorhabditis elegans)
Regulation of actin dynamics for phagocytic cup formation (Caenorhabditis elegans)
ABL phosphorylates WAVEs (Caenorhabditis elegans)
ADP [cytosol]
Autophosphorylation of PAK1 (Caenorhabditis elegans)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
Actin:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
Actin:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
ADP [cytosol]
Role of phospholipids in phagocytosis (Caenorhabditis elegans)
DAG stimulates protein kinase C-delta (Caenorhabditis elegans)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Caenorhabditis elegans)
NOD1/2 Signaling Pathway (Caenorhabditis elegans)
Activation of p38 MAPK (Caenorhabditis elegans)
ADP [cytosol]
Toll-like Receptor Cascades (Caenorhabditis elegans)
Toll Like Receptor 10 (TLR10) Cascade (Caenorhabditis elegans)
MyD88 cascade initiated on plasma membrane (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Caenorhabditis elegans)
Toll Like Receptor TLR1:TLR2 Cascade (Caenorhabditis elegans)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Caenorhabditis elegans)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Caenorhabditis elegans)
MyD88-independent TLR4 cascade (Caenorhabditis elegans)
TRIF (TICAM1)-mediated TLR4 signaling (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Caenorhabditis elegans)
MyD88 cascade initiated on plasma membrane (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Caenorhabditis elegans)
MyD88 dependent cascade initiated on endosome (Caenorhabditis elegans)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Caenorhabditis elegans)
MyD88 dependent cascade initiated on endosome (Caenorhabditis elegans)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Caenorhabditis elegans)
MAP kinase activation (Caenorhabditis elegans)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
ADP [cytosol]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Caenorhabditis elegans)
Mitochondrial Uncoupling (Caenorhabditis elegans)
The proton buffering model (Caenorhabditis elegans)
Protons are translocated from the intermembrane space to the matrix (Caenorhabditis elegans)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Cytosolic sulfonation of small molecules (Caenorhabditis elegans)
Transport and synthesis of PAPS (Caenorhabditis elegans)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Caenorhabditis elegans)
ADP [cytosol]
Glutathione conjugation (Caenorhabditis elegans)
Glutathione synthesis and recycling (Caenorhabditis elegans)
GCL ligates L-Glu to L-Cys (Caenorhabditis elegans)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Caenorhabditis elegans)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Caenorhabditis elegans)
ADP [cytosol]
Inositol phosphate metabolism (Caenorhabditis elegans)
Synthesis of IP3 and IP4 in the cytosol (Caenorhabditis elegans)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Caenorhabditis elegans)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Glutamate and glutamine metabolism (Caenorhabditis elegans)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of carbohydrates (Caenorhabditis elegans)
Formation of xylulose-5-phosphate (Caenorhabditis elegans)
XYLB phosphorylates D-xylulose (Caenorhabditis elegans)
ADP [cytosol]
Fructose metabolism (Caenorhabditis elegans)
Fructose catabolism (Caenorhabditis elegans)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Caenorhabditis elegans)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Caenorhabditis elegans)
ADP [cytosol]
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Caenorhabditis elegans)
ADP [cytosol]
Glycolysis (Caenorhabditis elegans)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Caenorhabditis elegans)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Caenorhabditis elegans)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Caenorhabditis elegans)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Caenorhabditis elegans)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Caenorhabditis elegans)
ADP [cytosol]
Glycogen metabolism (Caenorhabditis elegans)
Glycogen breakdown (glycogenolysis) (Caenorhabditis elegans)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Caenorhabditis elegans)
ADP [cytosol]
Glycosaminoglycan metabolism (Caenorhabditis elegans)
Transport and synthesis of PAPS (Caenorhabditis elegans)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Caenorhabditis elegans)
ADP [cytosol]
Pentose phosphate pathway (Caenorhabditis elegans)
RBKS phosphorylates ribose to R5P (Caenorhabditis elegans)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine metabolism (Caenorhabditis elegans)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Caenorhabditis elegans)
ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of steroids (Caenorhabditis elegans)
Bile acid and bile salt metabolism (Caenorhabditis elegans)
Recycling of bile acids and salts (Caenorhabditis elegans)
ABCC3 transports bile salts from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
Cholesterol biosynthesis (Caenorhabditis elegans)
MVD decarboxylates MVA5PP to IPPP (Caenorhabditis elegans)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Caenorhabditis elegans)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Caenorhabditis elegans)
ADP [cytosol]
Phospholipid metabolism (Caenorhabditis elegans)
Glycerophospholipid biosynthesis (Caenorhabditis elegans)
Synthesis of PC (Caenorhabditis elegans)
Casein kinase II phosphorylates STARD10 (Caenorhabditis elegans)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PE (Caenorhabditis elegans)
ETA is phosphorylated to PETA by CHK/ETNK (Caenorhabditis elegans)
ADP [cytosol]
PI Metabolism (Caenorhabditis elegans)
Synthesis of PIPs at the ER membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Caenorhabditis elegans)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Caenorhabditis elegans)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Caenorhabditis elegans)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Caenorhabditis elegans)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Caenorhabditis elegans)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Caenorhabditis elegans)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
Sphingolipid metabolism (Caenorhabditis elegans)
Glycosphingolipid metabolism (Caenorhabditis elegans)
Glycosphingolipid biosynthesis (Caenorhabditis elegans)
CERK phosphorylates CERA to form C1P (Caenorhabditis elegans)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Caenorhabditis elegans)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
CSNK1G2 phosphorylates p-CERT1-2 (Caenorhabditis elegans)
ADP [cytosol]
PRKD1,2,3 phosphorylates CERT1-2 (Caenorhabditis elegans)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Caenorhabditis elegans)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Caenorhabditis elegans)
ADP [cytosol]
Triglyceride metabolism (Caenorhabditis elegans)
Triglyceride biosynthesis (Caenorhabditis elegans)
Conversion of Glycerol to Glycerol-3-phosphate (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Caenorhabditis elegans)
eNOS activation (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Caenorhabditis elegans)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Caenorhabditis elegans)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Caenorhabditis elegans)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Caenorhabditis elegans)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Caenorhabditis elegans)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Caenorhabditis elegans)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Caenorhabditis elegans)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Caenorhabditis elegans)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Caenorhabditis elegans)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Caenorhabditis elegans)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Caenorhabditis elegans)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Caenorhabditis elegans)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Caenorhabditis elegans)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Caenorhabditis elegans)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Caenorhabditis elegans)
ADP [cytosol]
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Caenorhabditis elegans)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Caenorhabditis elegans)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Caenorhabditis elegans)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Caenorhabditis elegans)
ADP [cytosol]
Pyrimidine biosynthesis (Caenorhabditis elegans)
CAD hexamer transforms L-Gln to CAP (Caenorhabditis elegans)
ADP [cytosol]
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Caenorhabditis elegans)
ADP [cytosol]
Pyrimidine salvage (Caenorhabditis elegans)
UCKL1 phosphorylates urindine, cytidine (Caenorhabditis elegans)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Caenorhabditis elegans)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Caenorhabditis elegans)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of porphyrins (Caenorhabditis elegans)
Heme biosynthesis (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
Heme degradation (Caenorhabditis elegans)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Transport of RCbl within the body (Caenorhabditis elegans)
ABCC1 transports cytosolic RCbl to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of folate and pterines (Caenorhabditis elegans)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Caenorhabditis elegans)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Caenorhabditis elegans)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Caenorhabditis elegans)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Caenorhabditis elegans)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Caenorhabditis elegans)
RFK:Mg2+ phosphorylates RIB (Caenorhabditis elegans)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Caenorhabditis elegans)
Coenzyme A biosynthesis (Caenorhabditis elegans)
COASY phosphorylates DP-CoA (Caenorhabditis elegans)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Caenorhabditis elegans)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Caenorhabditis elegans)
2xPDKX:2xZn2+ phosphorylates PDX (Caenorhabditis elegans)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Caenorhabditis elegans)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of RNA (Caenorhabditis elegans)
Nonsense-Mediated Decay (NMD) (Caenorhabditis elegans)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Caenorhabditis elegans)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Caenorhabditis elegans)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Caenorhabditis elegans)
MK2 phosphorylates BRF1 (Caenorhabditis elegans)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Caenorhabditis elegans)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Caenorhabditis elegans)
Protein Kinase B (AKT) phosphorylates KSRP (Caenorhabditis elegans)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Caenorhabditis elegans)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Caenorhabditis elegans)
ADP [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
Synthesis of substrates in N-glycan biosythesis (Caenorhabditis elegans)
GDP-fucose biosynthesis (Caenorhabditis elegans)
FUK phosphorylates beta-Fuc to Fuc1P (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Caenorhabditis elegans)
MVD decarboxylates MVA5PP to IPPP (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Caenorhabditis elegans)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Caenorhabditis elegans)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Caenorhabditis elegans)
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Caenorhabditis elegans)
FN3K phosphorylates ketosamines (Caenorhabditis elegans)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Caenorhabditis elegans)
ADP [cytosol]
Protein folding (Caenorhabditis elegans)
Chaperonin-mediated protein folding (Caenorhabditis elegans)
Association of TriC/CCT with target proteins during biosynthesis (Caenorhabditis elegans)
Association of CCT/TriC with sphingosine kinase 1 (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Caenorhabditis elegans)
ATP binds G-protein beta associated TRiC/CCT (Caenorhabditis elegans)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Caenorhabditis elegans)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
CK2 phosphorylates PDCL (Caenorhabditis elegans)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Caenorhabditis elegans)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Caenorhabditis elegans)
GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Caenorhabditis elegans)
GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Caenorhabditis elegans)
GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Caenorhabditis elegans)
GNB5:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Surfactant metabolism (Caenorhabditis elegans)
ABCA3 transports PC, PG from ER membrane to lamellar body (Caenorhabditis elegans)
ADP [cytosol]
Translation (Caenorhabditis elegans)
Eukaryotic Translation Initiation (Caenorhabditis elegans)
Cap-dependent Translation Initiation (Caenorhabditis elegans)
Ribosomal scanning and start codon recognition (Caenorhabditis elegans)
Ribosomal scanning (Caenorhabditis elegans)
ADP [cytosol]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Ion homeostasis (Caenorhabditis elegans)
PRKACA phosphorylates TNNI3 (Caenorhabditis elegans)
ADP [cytosol]
Smooth Muscle Contraction (Caenorhabditis elegans)
ATP Hydrolysis By Myosin (Caenorhabditis elegans)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Caenorhabditis elegans)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Release Of ADP From Myosin (Caenorhabditis elegans)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Caenorhabditis elegans)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
Activation of NMDA receptors and postsynaptic events (Caenorhabditis elegans)
Post NMDA receptor activation events (Caenorhabditis elegans)
Activation of RAC1 downstream of NMDARs (Caenorhabditis elegans)
CaMKK autophosphorylates in the cytosol (Caenorhabditis elegans)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Caenorhabditis elegans)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Caenorhabditis elegans)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Caenorhabditis elegans)
ADP [cytosol]
Sensory Perception (Caenorhabditis elegans)
Visual phototransduction (Caenorhabditis elegans)
The canonical retinoid cycle in rods (twilight vision) (Caenorhabditis elegans)
ABCA4 mediates atRAL transport (Caenorhabditis elegans)
ADP [cytosol]
The phototransduction cascade (Caenorhabditis elegans)
Inactivation, recovery and regulation of the phototransduction cascade (Caenorhabditis elegans)
GRK1,4,7 phosphorylate MII to p-MII (Caenorhabditis elegans)
ADP [cytosol]
Signal Transduction (Caenorhabditis elegans)
Death Receptor Signaling (Caenorhabditis elegans)
p75 NTR receptor-mediated signalling (Caenorhabditis elegans)
Cell death signalling via NRAGE, NRIF and NADE (Caenorhabditis elegans)
NRAGE signals death through JNK (Caenorhabditis elegans)
GTP-bound RAC contributes to JNK activation (Caenorhabditis elegans)
ADP [cytosol]
Integrin signaling (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
ADP [cytosol]
Autophosphorylation of SRC (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
ADP [cytosol]
SYK activation by SRC (Caenorhabditis elegans)
ADP [cytosol]
Intracellular signaling by second messengers (Caenorhabditis elegans)
DAG and IP3 signaling (Caenorhabditis elegans)
CaM pathway (Caenorhabditis elegans)
Calmodulin induced events (Caenorhabditis elegans)
PKC phosphorylates GRK2 (Caenorhabditis elegans)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Caenorhabditis elegans)
ADP [cytosol]
PIP3 activates AKT signaling (Caenorhabditis elegans)
AKT phosphorylates targets in the cytosol (Caenorhabditis elegans)
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
ADP [cytosol]
AKT phosphorylates caspase-9 (Caenorhabditis elegans)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Caenorhabditis elegans)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Caenorhabditis elegans)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Caenorhabditis elegans)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
PTEN Regulation (Caenorhabditis elegans)
Regulation of PTEN gene transcription (Caenorhabditis elegans)
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
ADP [cytosol]
Regulation of PTEN stability and activity (Caenorhabditis elegans)
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Caenorhabditis elegans)
ADP [cytosol]
FRK phosphorylates PTEN (Caenorhabditis elegans)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
ADP [cytosol]
MAPK family signaling cascades (Caenorhabditis elegans)
MAPK1/MAPK3 signaling (Caenorhabditis elegans)
RAF-independent MAPK1/3 activation (Caenorhabditis elegans)
MAPK1 (ERK2) activation (Caenorhabditis elegans)
MAP2K2 phosphorylates MAPK1 (Caenorhabditis elegans)
ADP [cytosol]
MAPK3 (ERK1) activation (Caenorhabditis elegans)
Inactivation of MAP2K1 by CDK1 (Caenorhabditis elegans)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Caenorhabditis elegans)
ADP [cytosol]
RAF/MAP kinase cascade (Caenorhabditis elegans)
MAP2K and MAPK activation (Caenorhabditis elegans)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Caenorhabditis elegans)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Caenorhabditis elegans)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
ADP [cytosol]
Negative regulation of MAPK pathway (Caenorhabditis elegans)
MAPK12 phosphorylates PTPN3 (Caenorhabditis elegans)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Caenorhabditis elegans)
Activated MAPK phosphorylates RAF1 (Caenorhabditis elegans)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Caenorhabditis elegans)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Caenorhabditis elegans)
ADP [cytosol]
RAF activation (Caenorhabditis elegans)
MARK3 phosphorylates KSR1 (Caenorhabditis elegans)
ADP [cytosol]
RAS processing (Caenorhabditis elegans)
KRAS4B is phosphorylated on serine 181 (Caenorhabditis elegans)
ADP [cytosol]
MAPK6/MAPK4 signaling (Caenorhabditis elegans)
Autophosphorylation of PAK1,2,3 (Caenorhabditis elegans)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Caenorhabditis elegans)
ADP [cytosol]
MTOR signalling (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
ADP [cytosol]
mTORC1-mediated signalling (Caenorhabditis elegans)
Phosphorylation and activation of eIF4G by activated S6K1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Caenorhabditis elegans)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
ADP [cytosol]
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (i) signalling events (Caenorhabditis elegans)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Caenorhabditis elegans)
ADP [cytosol]
Opioid Signalling (Caenorhabditis elegans)
DARPP-32 events (Caenorhabditis elegans)
PKA phosphorylates PDE4B (Caenorhabditis elegans)
ADP [cytosol]
G-protein mediated events (Caenorhabditis elegans)
PLC beta mediated events (Caenorhabditis elegans)
Ca-dependent events (Caenorhabditis elegans)
CaM pathway (Caenorhabditis elegans)
Calmodulin induced events (Caenorhabditis elegans)
PKC phosphorylates GRK2 (Caenorhabditis elegans)
ADP [cytosol]
G alpha (q) signalling events (Caenorhabditis elegans)
Effects of PIP2 hydrolysis (Caenorhabditis elegans)
DAG kinase produces phosphatidic acid from DAG (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Hippo (Caenorhabditis elegans)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by NOTCH (Caenorhabditis elegans)
Signaling by NOTCH4 (Caenorhabditis elegans)
Negative regulation of NOTCH4 signaling (Caenorhabditis elegans)
AKT1 phosphorylates NOTCH4 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by PTK6 (Caenorhabditis elegans)
ERBB2 Activates PTK6 Signaling (Caenorhabditis elegans)
ERBB2 promotes PTK6 autophosphorylation (Caenorhabditis elegans)
ADP [cytosol]
PTK6 Down-Regulation (Caenorhabditis elegans)
SRMS phosphorylates PTK6 (Caenorhabditis elegans)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Caenorhabditis elegans)
PTK6 phosphorylates ARHGAP35 (Caenorhabditis elegans)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Caenorhabditis elegans)
PTK6 phosphorylates AKT1 (Caenorhabditis elegans)
ADP [cytosol]
PTK6 phosphorylates ARAP1 (Caenorhabditis elegans)
ADP [cytosol]
PTK6 phosphorylates CBL (Caenorhabditis elegans)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
Estrogen-stimulated signaling through PRKCZ (Caenorhabditis elegans)
PRKCZ autophosphorylates downstream of estrogen stimulation (Caenorhabditis elegans)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by ALK (Caenorhabditis elegans)
PI3K synthesizes PIP3 downstream of ALK (Caenorhabditis elegans)
ADP [cytosol]
Signaling by EGFR (Caenorhabditis elegans)
EGFR autophosphorylation (Caenorhabditis elegans)
ADP [cytosol]
EGFR downregulation (Caenorhabditis elegans)
EGFR phosphorylates EPS15 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Caenorhabditis elegans)
ADP [cytosol]
GAB1 signalosome (Caenorhabditis elegans)
GAB1 phosphorylation by EGFR kinase (Caenorhabditis elegans)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Caenorhabditis elegans)
ADP [cytosol]
Signaling by ERBB2 (Caenorhabditis elegans)
ERBB2 Activates PTK6 Signaling (Caenorhabditis elegans)
ERBB2 promotes PTK6 autophosphorylation (Caenorhabditis elegans)
ADP [cytosol]
PI3K events in ERBB2 signaling (Caenorhabditis elegans)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Caenorhabditis elegans)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Caenorhabditis elegans)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Caenorhabditis elegans)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Caenorhabditis elegans)
SHC1 phosphorylation by ERBB2 heterodimers (Caenorhabditis elegans)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Caenorhabditis elegans)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Caenorhabditis elegans)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Caenorhabditis elegans)
ADP [cytosol]
Signaling by ERBB4 (Caenorhabditis elegans)
PI3K events in ERBB4 signaling (Caenorhabditis elegans)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Caenorhabditis elegans)
ADP [cytosol]
Signaling by FGFR (Caenorhabditis elegans)
Signaling by FGFR1 (Caenorhabditis elegans)
Downstream signaling of activated FGFR1 (Caenorhabditis elegans)
FRS-mediated FGFR1 signaling (Caenorhabditis elegans)
Activated FGFR1 phosphorylates FRS2 (Caenorhabditis elegans)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Caenorhabditis elegans)
ADP [cytosol]
PI-3K cascade:FGFR1 (Caenorhabditis elegans)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates PLCG1 (Caenorhabditis elegans)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates SHC1 (Caenorhabditis elegans)
ADP [cytosol]
FGFR1 ligand binding and activation (Caenorhabditis elegans)
FGFR1b ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR1b (Caenorhabditis elegans)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Caenorhabditis elegans)
ADP [cytosol]
FGFR1c ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR1c (Caenorhabditis elegans)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Caenorhabditis elegans)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Caenorhabditis elegans)
ADP [cytosol]
Signaling by FGFR2 (Caenorhabditis elegans)
FGFR2 ligand binding and activation (Caenorhabditis elegans)
FGFR2b ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR2b (Caenorhabditis elegans)
ADP [cytosol]
FGFR2c ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR2c (Caenorhabditis elegans)
ADP [cytosol]
Signaling by FGFR3 (Caenorhabditis elegans)
FGFR3 ligand binding and activation (Caenorhabditis elegans)
FGFR3b ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR3b (Caenorhabditis elegans)
ADP [cytosol]
FGFR3c ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR3c (Caenorhabditis elegans)
ADP [cytosol]
Signaling by FGFR4 (Caenorhabditis elegans)
Downstream signaling of activated FGFR4 (Caenorhabditis elegans)
FRS-mediated FGFR4 signaling (Caenorhabditis elegans)
Activated FGFR4 phosphorylates FRS2 (Caenorhabditis elegans)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Caenorhabditis elegans)
ADP [cytosol]
PI-3K cascade:FGFR4 (Caenorhabditis elegans)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates PLCG1 (Caenorhabditis elegans)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates SHC1 (Caenorhabditis elegans)
ADP [cytosol]
FGFR4 ligand binding and activation (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR4 (Caenorhabditis elegans)
ADP [cytosol]
betaKlotho-mediated ligand binding (Caenorhabditis elegans)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Caenorhabditis elegans)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Caenorhabditis elegans)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Insulin receptor (Caenorhabditis elegans)
Insulin receptor signalling cascade (Caenorhabditis elegans)
IRS-mediated signalling (Caenorhabditis elegans)
PI3K Cascade (Caenorhabditis elegans)
Activation of AKT2 (Caenorhabditis elegans)
PDPK1 phosphorylates AKT2 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by MET (Caenorhabditis elegans)
MET Receptor Activation (Caenorhabditis elegans)
MET dimers autophosphorylate (Caenorhabditis elegans)
ADP [cytosol]
MET activates PI3K/AKT signaling (Caenorhabditis elegans)
MET bound PI3K generates PIP3 (Caenorhabditis elegans)
ADP [cytosol]
MET phosphorylates GAB1 (Caenorhabditis elegans)
ADP [cytosol]
MET activates STAT3 (Caenorhabditis elegans)
MET phosphorylates STAT3 (Caenorhabditis elegans)
ADP [cytosol]
MET promotes cell motility (Caenorhabditis elegans)
MET activates PTK2 signaling (Caenorhabditis elegans)
MET phosphorylates PTK2 (Caenorhabditis elegans)
ADP [cytosol]
PTK2 autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
SRC phosphorylates PTK2 (Caenorhabditis elegans)
ADP [cytosol]
Negative regulation of MET activity (Caenorhabditis elegans)
MET phosphorylates CBL (Caenorhabditis elegans)
ADP [cytosol]
Signaling by MST1 (Caenorhabditis elegans)
MST1R autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
Signaling by NTRKs (Caenorhabditis elegans)
Signaling by NTRK1 (TRKA) (Caenorhabditis elegans)
Signalling to ERKs (Caenorhabditis elegans)
Prolonged ERK activation events (Caenorhabditis elegans)
Frs2-mediated activation (Caenorhabditis elegans)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Caenorhabditis elegans)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Caenorhabditis elegans)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Caenorhabditis elegans)
ADP [cytosol]
Signalling to RAS (Caenorhabditis elegans)
p38MAPK events (Caenorhabditis elegans)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by PDGF (Caenorhabditis elegans)
Autophosphorylation of PDGF alpha receptors (Caenorhabditis elegans)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Caenorhabditis elegans)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Caenorhabditis elegans)
ADP [cytosol]
Downstream signal transduction (Caenorhabditis elegans)
Activation of Src (Caenorhabditis elegans)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Caenorhabditis elegans)
ADP [cytosol]
Signaling by SCF-KIT (Caenorhabditis elegans)
Regulation of KIT signaling (Caenorhabditis elegans)
PKC alpha interacts with and phosphorylates KIT (Caenorhabditis elegans)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Caenorhabditis elegans)
IGF1R signaling cascade (Caenorhabditis elegans)
IRS-related events triggered by IGF1R (Caenorhabditis elegans)
IRS-mediated signalling (Caenorhabditis elegans)
PI3K Cascade (Caenorhabditis elegans)
Activation of AKT2 (Caenorhabditis elegans)
PDPK1 phosphorylates AKT2 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
AXL autophosphorylates on Y779 and Y821 (Caenorhabditis elegans)
ADP [cytosol]
FYN autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
FYN phosphorylates PAK2 (Caenorhabditis elegans)
ADP [cytosol]
PAK2 autophorylates (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of SRC-1 (Caenorhabditis elegans)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Caenorhabditis elegans)
PDK1 phosphorylates PKC (Caenorhabditis elegans)
ADP [cytosol]
PKC autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Caenorhabditis elegans)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
ADP [cytosol]
PAK1-3 autophosphorylates (Caenorhabditis elegans)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Caenorhabditis elegans)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Caenorhabditis elegans)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Caenorhabditis elegans)
ADP [cytosol]
p38 MAPK activation by VEGFR (Caenorhabditis elegans)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Caenorhabditis elegans)
RHOBTB3 ATPase cycle (Caenorhabditis elegans)
RHOBTB3 hydrolyzes ATP (Caenorhabditis elegans)
RHOBTB3:ADP [trans-Golgi network membrane] (Caenorhabditis elegans)
ADP [cytosol]
Signaling by Rho GTPases (Caenorhabditis elegans)
RHO GTPase Effectors (Caenorhabditis elegans)
RHO GTPases Activate NADPH Oxidases (Caenorhabditis elegans)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Caenorhabditis elegans)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Caenorhabditis elegans)
ABL phosphorylates WAVEs (Caenorhabditis elegans)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
Actin:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Detachment of WASP/WAVE (Caenorhabditis elegans)
Mother filament:ARP2/3:actin:ADP [cytosol] (Caenorhabditis elegans)
Actin:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
ADP [cytosol]
RHO GTPases activate PAKs (Caenorhabditis elegans)
Autophosphorylation of PAK1,2,3 (Caenorhabditis elegans)
ADP [cytosol]
PAK1 phosphorylates FLNA (Caenorhabditis elegans)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Caenorhabditis elegans)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Caenorhabditis elegans)
ADP [cytosol]
RHO GTPases activate PKNs (Caenorhabditis elegans)
PDPK1 phosphorylates PKN1,2,3 (Caenorhabditis elegans)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Caenorhabditis elegans)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Caenorhabditis elegans)
ADP [cytosol]
Signaling by TGFB family members (Caenorhabditis elegans)
Signaling by BMP (Caenorhabditis elegans)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Caenorhabditis elegans)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Caenorhabditis elegans)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Caenorhabditis elegans)
TGF-beta receptor signaling activates SMADs (Caenorhabditis elegans)
Activated type I receptor phosphorylates SMAD2/3 directly (Caenorhabditis elegans)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Caenorhabditis elegans)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Caenorhabditis elegans)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Caenorhabditis elegans)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Caenorhabditis elegans)
ADP [cytosol]
Signaling by WNT (Caenorhabditis elegans)
Beta-catenin independent WNT signaling (Caenorhabditis elegans)
Ca2+ pathway (Caenorhabditis elegans)
Autophosphorylation and activation of CAMK2 (Caenorhabditis elegans)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)
ADP [cytosol]
PCP/CE pathway (Caenorhabditis elegans)
WNT5A-dependent internalization of FZD4 (Caenorhabditis elegans)
DVL2 is phosphorylated by PKC (Caenorhabditis elegans)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Caenorhabditis elegans)
AXIN is phosphorylated in the destruction complex (Caenorhabditis elegans)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Caenorhabditis elegans)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)
ADP [cytosol]
TCF dependent signaling in response to WNT (Caenorhabditis elegans)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Caenorhabditis elegans)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Caenorhabditis elegans)
ADP [cytosol]
WNT mediated activation of DVL (Caenorhabditis elegans)
CSNK2-mediated phosphorylation of DVL (Caenorhabditis elegans)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Caenorhabditis elegans)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)
ADP [cytosol]
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
ABC transporters in lipid homeostasis (Caenorhabditis elegans)
ABCA12 transports lipids from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Caenorhabditis elegans)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Caenorhabditis elegans)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
ABCA4 mediates atRAL transport (Caenorhabditis elegans)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Caenorhabditis elegans)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
HCO3- transport through ion channel (Caenorhabditis elegans)
ADP [cytosol]
Mitochondrial ABC transporters (Caenorhabditis elegans)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Caenorhabditis elegans)
ADP [cytosol]
The ABCC family mediates organic anion transport (Caenorhabditis elegans)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Caenorhabditis elegans)
ADP [cytosol]
Ion channel transport (Caenorhabditis elegans)
Ion transport by P-type ATPases (Caenorhabditis elegans)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Caenorhabditis elegans)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Caenorhabditis elegans)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Caenorhabditis elegans)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Caenorhabditis elegans)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Caenorhabditis elegans)
ADP [cytosol]
Stimuli-sensing channels (Caenorhabditis elegans)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)
ADP [cytosol]
Iron uptake and transport (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
ADP [cytosol]
Transferrin endocytosis and recycling (Caenorhabditis elegans)
Acidification of Tf:TfR1 containing endosome (Caenorhabditis elegans)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Caenorhabditis elegans)
Plasma lipoprotein assembly (Caenorhabditis elegans)
HDL assembly (Caenorhabditis elegans)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Caenorhabditis elegans)
ADP [cytosol]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Caenorhabditis elegans)
ADP [cytosol]
Vesicle-mediated transport (Caenorhabditis elegans)
Membrane Trafficking (Caenorhabditis elegans)
Clathrin-mediated endocytosis (Caenorhabditis elegans)
AAK1 phosphorylates AP-2 mu subunit at T156 (Caenorhabditis elegans)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Caenorhabditis elegans)
clathrin:HSPA8:ADP [cytosol] (Caenorhabditis elegans)
HSPA8:ADP [cytosol] (Caenorhabditis elegans)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Caenorhabditis elegans)
ADP [cytosol]
ER to Golgi Anterograde Transport (Caenorhabditis elegans)
COPI-mediated anterograde transport (Caenorhabditis elegans)
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Caenorhabditis elegans)
Golgi-to-ER retrograde transport (Caenorhabditis elegans)
COPI-independent Golgi-to-ER retrograde traffic (Caenorhabditis elegans)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
ADP [cytosol]
Rab regulation of trafficking (Caenorhabditis elegans)
RAB GEFs exchange GTP for GDP on RABs (Caenorhabditis elegans)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Caenorhabditis elegans)
ADP [cytosol]
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Canis familiaris)
ADP [cytosol]
Selective autophagy (Canis familiaris)
Mitophagy (Canis familiaris)
Receptor Mediated Mitophagy (Canis familiaris)
FUNDC1 is phosphorylated by CK2 (Canis familiaris)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Canis familiaris)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Canis familiaris)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Canis familiaris)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Canis familiaris)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Canis familiaris)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
ADP [cytosol]
Cell Cycle (Canis familiaris)
Cell Cycle Checkpoints (Canis familiaris)
G2/M Checkpoints (Canis familiaris)
G2/M DNA replication checkpoint (Canis familiaris)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)
ADP [cytosol]
Cell Cycle, Mitotic (Canis familiaris)
M Phase (Canis familiaris)
Mitotic Metaphase and Anaphase (Canis familiaris)
Mitotic Anaphase (Canis familiaris)
Nuclear Envelope (NE) Reassembly (Canis familiaris)
Initiation of Nuclear Envelope (NE) Reformation (Canis familiaris)
CDK1 phosphorylates LBR (Canis familiaris)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Canis familiaris)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Canis familiaris)
ADP [cytosol]
Mitotic Prometaphase (Canis familiaris)
Condensation of Prometaphase Chromosomes (Canis familiaris)
CK2 phosphorylates condensin I subunits (Canis familiaris)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Canis familiaris)
NEK6 and NEK7 phosphorylate EML4 (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates NUDC (Canis familiaris)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Canis familiaris)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Canis familiaris)
ADP [cytosol]
Mitotic Prophase (Canis familiaris)
Golgi Cisternae Pericentriolar Stack Reorganization (Canis familiaris)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Canis familiaris)
ADP [cytosol]
Nuclear Envelope Breakdown (Canis familiaris)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Canis familiaris)
CDK1:CCNB phosphorylates NEK9 (Canis familiaris)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Canis familiaris)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Canis familiaris)
CDK1 phosphorylates NUP98 (Canis familiaris)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Canis familiaris)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Canis familiaris)
G1 Phase (Canis familiaris)
Cyclin D associated events in G1 (Canis familiaris)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Canis familiaris)
ADP [cytosol]
Mitotic G2-G2/M phases (Canis familiaris)
G2/M Transition (Canis familiaris)
AURKA Activation by TPX2 (Canis familiaris)
TPX2 promotes AURKA autophosphorylation (Canis familiaris)
ADP [cytosol]
Centrosome maturation (Canis familiaris)
Loss of proteins required for interphase microtubule organization from the centrosome (Canis familiaris)
Loss of Nlp from mitotic centrosomes (Canis familiaris)
Plk1-mediated phosphorylation of Nlp (Canis familiaris)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Canis familiaris)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Canis familiaris)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Canis familiaris)
AURKA phosphorylates PHLDA1 (Canis familiaris)
ADP [cytosol]
Polo-like kinase mediated events (Canis familiaris)
Activation of Cdc25C (Canis familiaris)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Canis familiaris)
AJUBA facilitates AURKA autophosphorylation (Canis familiaris)
ADP [cytosol]
AURKA phosphorylates PLK1 (Canis familiaris)
ADP [cytosol]
CDK1 phosphorylates BORA (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates BORA (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates OPTN (Canis familiaris)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Canis familiaris)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Canis familiaris)
ADP [cytosol]
Cell-Cell communication (Canis familiaris)
Nephrin family interactions (Canis familiaris)
Phosphorylation of nephrin by FYN (Canis familiaris)
ADP [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular Senescence (Canis familiaris)
Oxidative Stress Induced Senescence (Canis familiaris)
MAP3K5 phosphorylates MKK3 and MKK6 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Cellular response to chemical stress (Canis familiaris)
KEAP1-NFE2L2 pathway (Canis familiaris)
Nuclear events mediated by NFE2L2 (Canis familiaris)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Canis familiaris)
SRXN1 reduces hyperoxidized PRDX1 dimer (Canis familiaris)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Canis familiaris)
ADP [cytosol]
Cellular response to heat stress (Canis familiaris)
Regulation of HSF1-mediated heat shock response (Canis familiaris)
Constitutive phosphorylation by pERK1/2 (Canis familiaris)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Canis familiaris)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Canis familiaris)
ADP [cytosol]
HSP70s:ADP [cytosol] (Canis familiaris)
HSP13:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP14:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA2:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA4:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA5:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA8:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA9:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Canis familiaris)
HSP70s:ADP [cytosol] (Canis familiaris)
HSP13:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP14:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA2:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA4:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA5:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA8:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSPA9:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Canis familiaris)
ATP binding to HSP90 triggers conformation change (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
ATP hydrolysis by HSP70 (Canis familiaris)
HSP40:HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Canis familiaris)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Canis familiaris)
HSP40:HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Unfolded Protein Response (UPR) (Canis familiaris)
IRE1alpha activates chaperones (Canis familiaris)
IRE1 dimer autophosphorylates (Canis familiaris)
ADP [cytosol]
PERK regulates gene expression (Canis familiaris)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Canis familiaris)
ADP [cytosol]
DNA Replication (Canis familiaris)
DNA Replication Pre-Initiation (Canis familiaris)
Assembly of the pre-replicative complex (Canis familiaris)
Assembly of the ORC complex at the origin of replication (Canis familiaris)
ORC6 is phosphorylated on T195 (Canis familiaris)
ADP [cytosol]
Developmental Biology (Canis familiaris)
MITF-M-regulated melanocyte development (Canis familiaris)
Transcriptional and post-translational regulation of MITF-M expression and activity (Canis familiaris)
MAPK-dependent phosphorylation of KARS (Canis familiaris)
ADP [cytosol]
Nervous system development (Canis familiaris)
Axon guidance (Canis familiaris)
EPH-Ephrin signaling (Canis familiaris)
EPH receptors autophosphorylate (Canis familiaris)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Canis familiaris)
SFKs phosphorylate VAV2,3 (Canis familiaris)
ADP [cytosol]
EPHB-mediated forward signaling (Canis familiaris)
EPHB phosphorylates TIAM1 (Canis familiaris)
ADP [cytosol]
PAK1 autophosphorylates (Canis familiaris)
ADP [cytosol]
Ephrin signaling (Canis familiaris)
PAKs autophosphorylate (Canis familiaris)
ADP [cytosol]
PAKs phosphorylate MLC (Canis familiaris)
ADP [cytosol]
L1CAM interactions (Canis familiaris)
Recycling pathway of L1 (Canis familiaris)
Phosphorylation of L1 by ERK (Canis familiaris)
ADP [cytosol]
Signal transduction by L1 (Canis familiaris)
Interaction of PAK1 with Rac1-GTP (Canis familiaris)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Canis familiaris)
ADP [cytosol]
Netrin-1 signaling (Canis familiaris)
DCC mediated attractive signaling (Canis familiaris)
Phosphorylation of DCC by Fyn (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Canis familiaris)
ADP [cytosol]
RET signaling (Canis familiaris)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Canis familiaris)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Canis familiaris)
ADP [cytosol]
RET tyrosine phosphorylation (Canis familiaris)
ADP [cytosol]
Reelin signalling pathway (Canis familiaris)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Canis familiaris)
ADP [cytosol]
Semaphorin interactions (Canis familiaris)
CRMPs in Sema3A signaling (Canis familiaris)
Phosphorylation of CRMPs by Cdk5 (Canis familiaris)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Canis familiaris)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Canis familiaris)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Canis familiaris)
Autophosphorylation of PAK (Canis familiaris)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Canis familiaris)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Canis familiaris)
ADP [cytosol]
Sema4D in semaphorin signaling (Canis familiaris)
Sema4D induced cell migration and growth-cone collapse (Canis familiaris)
SEMA4D interacts with Plexin-B1:ErbB2 (Canis familiaris)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Canis familiaris)
SEMA4D interacts with Plexin-B1:Met (Canis familiaris)
ADP [cytosol]
Signaling by ROBO receptors (Canis familiaris)
ROBO receptors bind AKAP5 (Canis familiaris)
PKC phosphorylates ROBO3.1 (Canis familiaris)
ADP [cytosol]
Drug ADME (Canis familiaris)
Aspirin ADME (Canis familiaris)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Canis familiaris)
ADP [cytosol]
Azathioprine ADME (Canis familiaris)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Canis familiaris)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Canis familiaris)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Canis familiaris)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Canis familiaris)
ADP [cytosol]
Ciprofloxacin ADME (Canis familiaris)
ABCG2 transports Cipro from hepatic cell to extracellular space (Canis familiaris)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Canis familiaris)
ADP [cytosol]
Paracetamol ADME (Canis familiaris)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Canis familiaris)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Canis familiaris)
ADP [cytosol]
Prednisone ADME (Canis familiaris)
ABCB1 transports PREDN,PREDL out of hepatic cells (Canis familiaris)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Canis familiaris)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Canis familiaris)
ADP [cytosol]
Ribavirin ADME (Canis familiaris)
ADK phosphorylates RBV (Canis familiaris)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Canis familiaris)
ADP [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
Regulation of TP53 Activity (Canis familiaris)
Regulation of TP53 Expression and Degradation (Canis familiaris)
Regulation of TP53 Degradation (Canis familiaris)
PDPK1 phosphorylates SGK1 (Canis familiaris)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Canis familiaris)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Canis familiaris)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Canis familiaris)
p-AMPK phosphorylates TSC1:TSC2 (Canis familiaris)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Canis familiaris)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Canis familiaris)
PLK2 phosphorylates CENPJ (Canis familiaris)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Canis familiaris)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Canis familiaris)
Regulation of RUNX3 expression and activity (Canis familiaris)
SRC phosphorylates RUNX3 (Canis familiaris)
ADP [cytosol]
Hemostasis (Canis familiaris)
Cell surface interactions at the vascular wall (Canis familiaris)
PECAM1 interactions (Canis familiaris)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Canis familiaris)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Canis familiaris)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Canis familiaris)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Canis familiaris)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Canis familiaris)
ADP [cytosol]
Kinesins (Canis familiaris)
Kinesins move along microtubules consuming ATP (Canis familiaris)
ADP [cytosol]
Platelet activation, signaling and aggregation (Canis familiaris)
Effects of PIP2 hydrolysis (Canis familiaris)
DAG kinase produces phosphatidic acid from DAG (Canis familiaris)
ADP [cytosol]
GPVI-mediated activation cascade (Canis familiaris)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Canis familiaris)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
SYK autophosphorylates (Canis familiaris)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Canis familiaris)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Canis familiaris)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Canis familiaris)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Canis familiaris)
Integrin signaling (Canis familiaris)
Autophosphorylation of PTK2 at Y397 (Canis familiaris)
ADP [cytosol]
Autophosphorylation of SRC (Canis familiaris)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Canis familiaris)
ADP [cytosol]
SYK activation by SRC (Canis familiaris)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Canis familiaris)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Canis familiaris)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Canis familiaris)
Disinhibition of SNARE formation (Canis familiaris)
Phosphorylation of Platelet Sec-1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Canis familiaris)
ADP [cytosol]
Platelet degranulation (Canis familiaris)
ABCC4 accumulation of dense granule contents (Canis familiaris)
ADP [cytosol]
Signal amplification (Canis familiaris)
ADP signalling through P2Y purinoceptor 1 (Canis familiaris)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Canis familiaris)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Canis familiaris)
ADP [cytosol]
Platelet homeostasis (Canis familiaris)
Platelet sensitization by LDL (Canis familiaris)
FGR binds and phosphorylates LRP8 (Canis familiaris)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Canis familiaris)
ADP [cytosol]
PECAM1 is phosphorylated (Canis familiaris)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Canis familiaris)
ADP [cytosol]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Costimulation by the CD28 family (Canis familiaris)
CD28 co-stimulation (Canis familiaris)
CD28 dependent PI3K/Akt signaling (Canis familiaris)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Canis familiaris)
ADP [cytosol]
CD28 dependent Vav1 pathway (Canis familiaris)
Activation of Vav1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of CD28 (Canis familiaris)
ADP [cytosol]
CTLA4 inhibitory signaling (Canis familiaris)
Phosphorylation of CTLA-4 (Canis familiaris)
ADP [cytosol]
PD-1 signaling (Canis familiaris)
Phosphorylation of PD-1 (Canis familiaris)
ADP [cytosol]
MHC class II antigen presentation (Canis familiaris)
Transport of antigen loaded MHC II molecules to surface (Canis familiaris)
ADP [cytosol]
Rap1 signalling (Canis familiaris)
PKA/PKG phosphorylate Rap1GAP2 (Canis familiaris)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Canis familiaris)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Canis familiaris)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Canis familiaris)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Canis familiaris)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)
ADP [cytosol]
CD22 mediated BCR regulation (Canis familiaris)
LYN phosphorylates CD22 (Canis familiaris)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Canis familiaris)
Activation of NF-kappaB in B cells (Canis familiaris)
Activated IKK phosphorylates I-kappaB (Canis familiaris)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Canis familiaris)
ADP [cytosol]
TCR signaling (Canis familiaris)
Downstream TCR signaling (Canis familiaris)
Activation of IKK complex (Canis familiaris)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Canis familiaris)
ADP [cytosol]
Change of PKC theta conformation (Canis familiaris)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of Bcl10 (Canis familiaris)
ADP [cytosol]
Phosphorylation of CARMA1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of PKC theta (Canis familiaris)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
ADP [cytosol]
Generation of second messenger molecules (Canis familiaris)
Phosphorylation of PLC-gamma1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of SLP-76 (Canis familiaris)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Canis familiaris)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Canis familiaris)
Activation of Lck (Canis familiaris)
ADP [cytosol]
Inactivation of Lck by Csk (Canis familiaris)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Canis familiaris)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Canis familiaris)
Activation of ZAP-70 (Canis familiaris)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Canis familiaris)
ADP [cytosol]
Cytokine Signaling in Immune system (Canis familiaris)
FLT3 Signaling (Canis familiaris)
Active FLT3 phosphorylates CDKN1B (Canis familiaris)
ADP [cytosol]
FLT3 phosphorylates GRB10 (Canis familiaris)
ADP [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Canis familiaris)
ADP [cytosol]
Negative regulation of FLT3 (Canis familiaris)
FLT3 phosphorylates CBL (Canis familiaris)
ADP [cytosol]
Growth hormone receptor signaling (Canis familiaris)
JAK2 phosphorylation (Canis familiaris)
ADP [cytosol]
Lyn activates ERK (Canis familiaris)
ADP [cytosol]
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
PKR-mediated signaling (Canis familiaris)
p-PKR dimer phosphorylates CDK1 (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates MAPT (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Canis familiaris)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Canis familiaris)
ADP [cytosol]
Interferon alpha/beta signaling (Canis familiaris)
Activation of JAK kinases (Canis familiaris)
ADP [cytosol]
Formation of p-STAT1 homodimer (Canis familiaris)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Canis familiaris)
ADP [cytosol]
Phosphorylation of STAT2 (Canis familiaris)
ADP [cytosol]
Interferon gamma signaling (Canis familiaris)
IFNG signaling activates MAPKs (Canis familiaris)
JAK1-activated RAF1 phosphorylates MAPKs (Canis familiaris)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Canis familiaris)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Canis familiaris)
ADP [cytosol]
Phosphorylation of JAK2 (Canis familiaris)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Canis familiaris)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Canis familiaris)
ADP [cytosol]
Transphosphorylation of JAK1 (Canis familiaris)
ADP [cytosol]
Prolactin receptor signaling (Canis familiaris)
JAK2 phosphorylation (Canis familiaris)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Canis familiaris)
ADP [cytosol]
Signaling by Interleukins (Canis familiaris)
Interleukin-1 family signaling (Canis familiaris)
Interleukin-1 signaling (Canis familiaris)
IKBA is phosphorylated by Phospho IKKB kinase (Canis familiaris)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Canis familiaris)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Canis familiaris)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Canis familiaris)
ADP [cytosol]
Interleukin-37 signaling (Canis familiaris)
STAT3 phosphorylation (Canis familiaris)
ADP [cytosol]
TBK1 phosphorylation (Canis familiaris)
ADP [cytosol]
Interleukin-38 signaling (Canis familiaris)
MAPK8 phosphorylation (Canis familiaris)
ADP [cytosol]
Interleukin-10 signaling (Canis familiaris)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Canis familiaris)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Canis familiaris)
ADP [cytosol]
Interleukin-12 family signaling (Canis familiaris)
Interleukin-12 signaling (Canis familiaris)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Canis familiaris)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)
ADP [cytosol]
Interleukin-23 signaling (Canis familiaris)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Canis familiaris)
ADP [cytosol]
Interleukin-27 signaling (Canis familiaris)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Canis familiaris)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Canis familiaris)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Canis familiaris)
ADP [cytosol]
Interleukin-35 Signalling (Canis familiaris)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Canis familiaris)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Canis familiaris)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Canis familiaris)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Canis familiaris)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Canis familiaris)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Canis familiaris)
ADP [cytosol]
Interleukin-17 signaling (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
Interleukin-2 family signaling (Canis familiaris)
Interleukin receptor SHC signaling (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
ADP [cytosol]
Interleukin-15 signaling (Canis familiaris)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Canis familiaris)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)
ADP [cytosol]
Interleukin-2 signaling (Canis familiaris)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Canis familiaris)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Canis familiaris)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Canis familiaris)
ADP [cytosol]
SYK is a substrate for JAK1 (Canis familiaris)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Canis familiaris)
ADP [cytosol]
Interleukin-21 signaling (Canis familiaris)
IL21 receptor JAK phosphorylation (Canis familiaris)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Canis familiaris)
ADP [cytosol]
Interleukin-9 signaling (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Canis familiaris)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Canis familiaris)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Canis familiaris)
ADP [cytosol]
Interleukin-20 family signaling (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Canis familiaris)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Canis familiaris)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Canis familiaris)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Canis familiaris)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Canis familiaris)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Canis familiaris)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Canis familiaris)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Canis familiaris)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Canis familiaris)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Canis familiaris)
Activation of STAT5a/b by JAK2 (Canis familiaris)
ADP [cytosol]
Interleukin receptor SHC signaling (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
ADP [cytosol]
JAK2 is phosphorylated, activated (Canis familiaris)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Canis familiaris)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Canis familiaris)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Canis familiaris)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Canis familiaris)
ADP [cytosol]
Interleukin-6 family signaling (Canis familiaris)
Interleukin-6 signaling (Canis familiaris)
IL6ST is tyrosine phosphorylated (Canis familiaris)
ADP [cytosol]
JAK activation (Canis familiaris)
ADP [cytosol]
PTPN11 is phosphorylated (Canis familiaris)
ADP [cytosol]
Serine phosphorylation of STATs (Canis familiaris)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Canis familiaris)
ADP [cytosol]
Interleukin-7 signaling (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Canis familiaris)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Canis familiaris)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Canis familiaris)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Canis familiaris)
NIK-->noncanonical NF-kB signaling (Canis familiaris)
Active NIK phosphorylates IKKA dimer (Canis familiaris)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Canis familiaris)
ADP [cytosol]
NIK autophosphorylates on T559 (Canis familiaris)
ADP [cytosol]
Innate Immune System (Canis familiaris)
Alpha-protein kinase 1 signaling pathway (Canis familiaris)
ALPK1 phosphorylates TIFA (Canis familiaris)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Canis familiaris)
ADP [cytosol]
Antimicrobial peptides (Canis familiaris)
Ion influx/efflux at host-pathogen interface (Canis familiaris)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Canis familiaris)
ADP [cytosol]
C-type lectin receptors (CLRs) (Canis familiaris)
CD209 (DC-SIGN) signaling (Canis familiaris)
PAK phosphorylates p21 RAF1 on S338 (Canis familiaris)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Canis familiaris)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Canis familiaris)
Dectin-1 mediated noncanonical NF-kB signaling (Canis familiaris)
Active NIK phosphorylates IKKA dimer (Canis familiaris)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Canis familiaris)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Canis familiaris)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Canis familiaris)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Canis familiaris)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Canis familiaris)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
ADP [cytosol]
Dectin-2 family (Canis familiaris)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Canis familiaris)
ADP [cytosol]
SYK autophosphorylates (Canis familiaris)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Canis familiaris)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Canis familiaris)
STING mediated induction of host immune responses (Canis familiaris)
STAT6-mediated induction of chemokines (Canis familiaris)
p-S407-STAT6 is phosphorylated at Tyr641 (Canis familiaris)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Canis familiaris)
RIP-mediated NFkB activation via ZBP1 (Canis familiaris)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
DAP12 interactions (Canis familiaris)
DAP12 signaling (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of SYK (Canis familiaris)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Canis familiaris)
TRAF6 mediated NF-kB activation (Canis familiaris)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
Autophosphorylation of LYN kinase (Canis familiaris)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Canis familiaris)
Autophosphorylation of BTK/ITK (Canis familiaris)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Canis familiaris)
ADP [cytosol]
FCERI mediated MAPK activation (Canis familiaris)
Autophosphorylation of PAK (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of VAV (Canis familiaris)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Canis familiaris)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
FCERI mediated NF-kB activation (Canis familiaris)
Activation of TAK1 complex bound to pUb-TRAF6 (Canis familiaris)
ADP [cytosol]
Autophosphorylation of PKC-theta (Canis familiaris)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Canis familiaris)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of PKC-theta (Canis familiaris)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Canis familiaris)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Canis familiaris)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Canis familiaris)
Phosphorylation of NTAL by p-SYK/Lyn (Canis familiaris)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Canis familiaris)
FCGR activation (Canis familiaris)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Canis familiaris)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Canis familiaris)
ABL phosphorylates WAVEs (Canis familiaris)
ADP [cytosol]
Autophosphorylation of PAK1 (Canis familiaris)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Canis familiaris)
Mother filament:ARP2/3:actin:ADP [cytosol] (Canis familiaris)
Actin:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Detachment of WASP/WAVE (Canis familiaris)
Mother filament:ARP2/3:actin:ADP [cytosol] (Canis familiaris)
Actin:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Canis familiaris)
Actin filament bound Myosin-X [plasma membrane] (Canis familiaris)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of VAV (Canis familiaris)
ADP [cytosol]
Role of myosins in phagosome formation (Canis familiaris)
Myosin-Actin filaments [cytosol] (Canis familiaris)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Canis familiaris)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Canis familiaris)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Canis familiaris)
ADP [cytosol]
Role of phospholipids in phagocytosis (Canis familiaris)
DAG stimulates protein kinase C-delta (Canis familiaris)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of PLCG (Canis familiaris)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Canis familiaris)
NOD1/2 Signaling Pathway (Canis familiaris)
Activation of p38 MAPK (Canis familiaris)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Canis familiaris)
ADP [cytosol]
Toll-like Receptor Cascades (Canis familiaris)
Toll Like Receptor 10 (TLR10) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Canis familiaris)
Toll Like Receptor TLR1:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Canis familiaris)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Canis familiaris)
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Canis familiaris)
MyD88-independent TLR4 cascade (Canis familiaris)
TRIF (TICAM1)-mediated TLR4 signaling (Canis familiaris)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Canis familiaris)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Canis familiaris)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Canis familiaris)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Canis familiaris)
Activation of TAK1 complex bound to activated TLR4 complex (Canis familiaris)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Canis familiaris)
MyD88 cascade initiated on plasma membrane (Canis familiaris)
IRAK1 recruits IKK complex (Canis familiaris)
IRAK1 phosphorylates Pellino (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Canis familiaris)
MyD88 dependent cascade initiated on endosome (Canis familiaris)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Canis familiaris)
ADP [cytosol]
MAP kinase activation (Canis familiaris)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
ADP [cytosol]
MAP3K8 is phosphorylated (Canis familiaris)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
ADP [cytosol]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Pyruvate metabolism (Canis familiaris)
PKM dephosphorylates PEP to PYR (Canis familiaris)
ADP [cytosol]
Regulation of pyruvate metabolism (Canis familiaris)
NEK1 phosphorylates ME1 (Canis familiaris)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Canis familiaris)
Mitochondrial Uncoupling (Canis familiaris)
The proton buffering model (Canis familiaris)
Protons are translocated from the intermembrane space to the matrix (Canis familiaris)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
Transport and synthesis of PAPS (Canis familiaris)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Canis familiaris)
ADP [cytosol]
Glutathione conjugation (Canis familiaris)
Glutathione synthesis and recycling (Canis familiaris)
GCL ligates L-Glu to L-Cys (Canis familiaris)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Canis familiaris)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Canis familiaris)
ADP [cytosol]
Inositol phosphate metabolism (Canis familiaris)
Synthesis of IP3 and IP4 in the cytosol (Canis familiaris)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Canis familiaris)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Canis familiaris)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Canis familiaris)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Canis familiaris)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Canis familiaris)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Canis familiaris)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Canis familiaris)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Canis familiaris)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Canis familiaris)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)
ADP [cytosol]
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Acetylcholine regulates insulin secretion (Canis familiaris)
Protein kinase C, alpha type phosphorylates MARCKS (Canis familiaris)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Canis familiaris)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Creatine metabolism (Canis familiaris)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Canis familiaris)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Canis familiaris)
ADP [cytosol]
Glutamate and glutamine metabolism (Canis familiaris)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Canis familiaris)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Canis familiaris)
ADP [cytosol]
Histidine catabolism (Canis familiaris)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Canis familiaris)
ADP [cytosol]
Metabolism of carbohydrates (Canis familiaris)
Formation of xylulose-5-phosphate (Canis familiaris)
XYLB phosphorylates D-xylulose (Canis familiaris)
ADP [cytosol]
Fructose metabolism (Canis familiaris)
Fructose catabolism (Canis familiaris)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Canis familiaris)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Canis familiaris)
ADP [cytosol]
Galactose catabolism (Canis familiaris)
GALK1 phosphorylates Gal to Gal1P (Canis familiaris)
ADP [cytosol]
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Canis familiaris)
ADP [cytosol]
Glycolysis (Canis familiaris)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Canis familiaris)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Canis familiaris)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Canis familiaris)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Canis familiaris)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Canis familiaris)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Canis familiaris)
ADP [cytosol]
Glycogen metabolism (Canis familiaris)
Glycogen breakdown (glycogenolysis) (Canis familiaris)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Canis familiaris)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)
ADP [cytosol]
Glycosaminoglycan metabolism (Canis familiaris)
Transport and synthesis of PAPS (Canis familiaris)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Canis familiaris)
ADP [cytosol]
Pentose phosphate pathway (Canis familiaris)
RBKS phosphorylates ribose to R5P (Canis familiaris)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Canis familiaris)
ADP [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine metabolism (Canis familiaris)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Canis familiaris)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Canis familiaris)
ACLY tetramer transforms CIT to Ac-CoA (Canis familiaris)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Canis familiaris)
ADP [cytosol]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
ABCB11 transports bile salts from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
ABCB11 transports bile salts from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
Cholesterol biosynthesis (Canis familiaris)
MVD decarboxylates MVA5PP to IPPP (Canis familiaris)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Canis familiaris)
ADP [cytosol]
Phospholipid metabolism (Canis familiaris)
Glycerophospholipid biosynthesis (Canis familiaris)
Synthesis of PC (Canis familiaris)
Casein kinase II phosphorylates STARD10 (Canis familiaris)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Canis familiaris)
ADP [cytosol]
Synthesis of PE (Canis familiaris)
ETA is phosphorylated to PETA by CHK/ETNK (Canis familiaris)
ADP [cytosol]
PI Metabolism (Canis familiaris)
Synthesis of PIPs at the ER membrane (Canis familiaris)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Canis familiaris)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Canis familiaris)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Canis familiaris)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Canis familiaris)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Canis familiaris)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Canis familiaris)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Canis familiaris)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Canis familiaris)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Canis familiaris)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Canis familiaris)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Canis familiaris)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Canis familiaris)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Canis familiaris)
BMX phosphorylates RUFY1 (Canis familiaris)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)
ADP [cytosol]
Sphingolipid metabolism (Canis familiaris)
Glycosphingolipid metabolism (Canis familiaris)
Glycosphingolipid biosynthesis (Canis familiaris)
CERK phosphorylates CERA to form C1P (Canis familiaris)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Canis familiaris)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Canis familiaris)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Canis familiaris)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Canis familiaris)
ADP [cytosol]
Triglyceride metabolism (Canis familiaris)
Triglyceride biosynthesis (Canis familiaris)
Conversion of Glycerol to Glycerol-3-phosphate (Canis familiaris)
ADP [cytosol]
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Canis familiaris)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Canis familiaris)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Canis familiaris)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Canis familiaris)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Canis familiaris)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Canis familiaris)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Canis familiaris)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Canis familiaris)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Canis familiaris)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Canis familiaris)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Canis familiaris)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Canis familiaris)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Canis familiaris)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Canis familiaris)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Canis familiaris)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Canis familiaris)
ADP [cytosol]
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Canis familiaris)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Canis familiaris)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Canis familiaris)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Canis familiaris)
ADP [cytosol]
Pyrimidine biosynthesis (Canis familiaris)
CAD hexamer transforms L-Gln to CAP (Canis familiaris)
ADP [cytosol]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Canis familiaris)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Canis familiaris)
ADP [cytosol]
Pyrimidine catabolism (Canis familiaris)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Canis familiaris)
ADP [cytosol]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Canis familiaris)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Canis familiaris)
ADP [cytosol]
Pyrimidine salvage (Canis familiaris)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Canis familiaris)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Canis familiaris)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Canis familiaris)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Canis familiaris)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Canis familiaris)
ADP [cytosol]
Metabolism of porphyrins (Canis familiaris)
Heme biosynthesis (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
Heme degradation (Canis familiaris)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of cofactors (Canis familiaris)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Canis familiaris)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Canis familiaris)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Transport of RCbl within the body (Canis familiaris)
ABCC1 transports cytosolic RCbl to extracellular region (Canis familiaris)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Canis familiaris)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Canis familiaris)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Canis familiaris)
ADP [cytosol]
Metabolism of folate and pterines (Canis familiaris)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Canis familiaris)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Canis familiaris)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Canis familiaris)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Canis familiaris)
ADP [cytosol]
Nicotinate metabolism (Canis familiaris)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Canis familiaris)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Canis familiaris)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Canis familiaris)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Canis familiaris)
RFK:Mg2+ phosphorylates RIB (Canis familiaris)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Canis familiaris)
Coenzyme A biosynthesis (Canis familiaris)
COASY phosphorylates DP-CoA (Canis familiaris)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Canis familiaris)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Canis familiaris)
ADP [cytosol]
PANK2 phosphorylates PanK (Canis familiaris)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Canis familiaris)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Canis familiaris)
2xPDKX:2xZn2+ phosphorylates PDX (Canis familiaris)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Canis familiaris)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Canis familiaris)
ADP [cytosol]
Metabolism of RNA (Canis familiaris)
Nonsense-Mediated Decay (NMD) (Canis familiaris)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Canis familiaris)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
ADP [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
Synthesis of substrates in N-glycan biosythesis (Canis familiaris)
GDP-fucose biosynthesis (Canis familiaris)
FUK phosphorylates beta-Fuc to Fuc1P (Canis familiaris)
ADP [cytosol]
Sialic acid metabolism (Canis familiaris)
GNE phosphorylates ManNAc to ManNAc-6-P (Canis familiaris)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Canis familiaris)
MVD decarboxylates MVA5PP to IPPP (Canis familiaris)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Canis familiaris)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Canis familiaris)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Canis familiaris)
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
GBF1 stimulates ARF nucleotide exchange (Canis familiaris)
ADP [cytosol]
COPII-mediated vesicle transport (Canis familiaris)
CSNK1D phosphorylates SEC23 (Canis familiaris)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Canis familiaris)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Canis familiaris)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Canis familiaris)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
FN3K phosphorylates ketosamines (Canis familiaris)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Canis familiaris)
ADP [cytosol]
Protein folding (Canis familiaris)
Chaperonin-mediated protein folding (Canis familiaris)
Association of TriC/CCT with target proteins during biosynthesis (Canis familiaris)
Association of CCT/TriC with sphingosine kinase 1 (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Canis familiaris)
ATP binds G-protein beta associated TRiC/CCT (Canis familiaris)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Canis familiaris)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
CK2 phosphorylates PDCL (Canis familiaris)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Canis familiaris)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Canis familiaris)
GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Canis familiaris)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Canis familiaris)
GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Canis familiaris)
GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Canis familiaris)
GNB5:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Surfactant metabolism (Canis familiaris)
ABCA3 transports PC, PG from ER membrane to lamellar body (Canis familiaris)
ADP [cytosol]
Translation (Canis familiaris)
Eukaryotic Translation Initiation (Canis familiaris)
Cap-dependent Translation Initiation (Canis familiaris)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Canis familiaris)
Cap-bound mRNA is activated by helicases (Canis familiaris)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Canis familiaris)
Ribosomal scanning (Canis familiaris)
ADP [cytosol]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Ion homeostasis (Canis familiaris)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Canis familiaris)
ADP [cytosol]
PRKACA phosphorylates PLN (Canis familiaris)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Canis familiaris)
ADP [cytosol]
Smooth Muscle Contraction (Canis familiaris)
ATP Hydrolysis By Myosin (Canis familiaris)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Canis familiaris)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Canis familiaris)
ADP [cytosol]
Release Of ADP From Myosin (Canis familiaris)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Canis familiaris)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Canis familiaris)
ADP [cytosol]
Striated Muscle Contraction (Canis familiaris)
ATP Hydrolysis By Myosin (Canis familiaris)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
ADP Bound Myosin Complex [cytosol] (Canis familiaris)
ADP [cytosol]
Release Of ADP From Myosin (Canis familiaris)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Canis familiaris)
ADP Bound Myosin Complex [cytosol] (Canis familiaris)
ADP [cytosol]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
Activation of NMDA receptors and postsynaptic events (Canis familiaris)
Post NMDA receptor activation events (Canis familiaris)
Activation of RAC1 downstream of NMDARs (Canis familiaris)
CaMKK autophosphorylates in the cytosol (Canis familiaris)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Canis familiaris)
Trafficking of AMPA receptors (Canis familiaris)
Trafficking of GluR1-containing AMPA receptors (Canis familiaris)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Canis familiaris)
Endocytosis of Ca impermeable AMPA receptors (Canis familiaris)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Canis familiaris)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Canis familiaris)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Canis familiaris)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Canis familiaris)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Canis familiaris)
ADP [cytosol]
Programmed Cell Death (Canis familiaris)
Apoptosis (Canis familiaris)
Caspase activation via extrinsic apoptotic signalling pathway (Canis familiaris)
Caspase activation via Dependence Receptors in the absence of ligand (Canis familiaris)
Activation of caspase-3 (Canis familiaris)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Canis familiaris)
Activation of BH3-only proteins (Canis familiaris)
Activation of BIM and translocation to mitochondria (Canis familiaris)
Phosphorylation of BIM by JNK (Canis familiaris)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Canis familiaris)
Phosphorylation of DLC2 by MAPK8 (Canis familiaris)
ADP [cytosol]
Apoptotic factor-mediated response (Canis familiaris)
Cytochrome c-mediated apoptotic response (Canis familiaris)
Activation of caspases through apoptosome-mediated cleavage (Canis familiaris)
Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Canis familiaris)
ADP [cytosol]
Formation of apoptosome (Canis familiaris)
CYCS binds to APAF1 (Canis familiaris)
ADP [cytosol]
APAF1:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Canis familiaris)
ADP [cytosol]
Regulation of the apoptosome activity (Canis familiaris)
APAF1 binds AVEN (Canis familiaris)
APAF1:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
APAF1:AVEN [cytosol] (Canis familiaris)
APAF1:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Canis familiaris)
ADP [cytosol]
Regulated Necrosis (Canis familiaris)
RIPK1-mediated regulated necrosis (Canis familiaris)
RIPK1 is phosphorylated (Canis familiaris)
ADP [cytosol]
RIPK3 is phosphorylated (Canis familiaris)
ADP [cytosol]
Sensory Perception (Canis familiaris)
Visual phototransduction (Canis familiaris)
The canonical retinoid cycle in rods (twilight vision) (Canis familiaris)
ABCA4 mediates atRAL transport (Canis familiaris)
ADP [cytosol]
The phototransduction cascade (Canis familiaris)
Inactivation, recovery and regulation of the phototransduction cascade (Canis familiaris)
GRK1,4,7 phosphorylate MII to p-MII (Canis familiaris)
ADP [cytosol]
Signal Transduction (Canis familiaris)
Death Receptor Signaling (Canis familiaris)
TNF signaling (Canis familiaris)
Regulation of TNFR1 signaling (Canis familiaris)
CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Canis familiaris)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Canis familiaris)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Canis familiaris)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Canis familiaris)
Cell death signalling via NRAGE, NRIF and NADE (Canis familiaris)
NRAGE signals death through JNK (Canis familiaris)
GTP-bound RAC contributes to JNK activation (Canis familiaris)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Canis familiaris)
ADP [cytosol]
p75NTR signals via NF-kB (Canis familiaris)
NF-kB is activated and signals survival (Canis familiaris)
IKKbeta is activated (Canis familiaris)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Canis familiaris)
ADP [cytosol]
Integrin signaling (Canis familiaris)
Autophosphorylation of PTK2 at Y397 (Canis familiaris)
ADP [cytosol]
Autophosphorylation of SRC (Canis familiaris)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Canis familiaris)
ADP [cytosol]
SYK activation by SRC (Canis familiaris)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Canis familiaris)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Canis familiaris)
ADP [cytosol]
Intracellular signaling by second messengers (Canis familiaris)
DAG and IP3 signaling (Canis familiaris)
CaM pathway (Canis familiaris)
Calmodulin induced events (Canis familiaris)
PKC phosphorylates GRK2 (Canis familiaris)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Canis familiaris)
ADP [cytosol]
PIP3 activates AKT signaling (Canis familiaris)
Negative regulation of the PI3K/AKT network (Canis familiaris)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Canis familiaris)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Canis familiaris)
ADP [cytosol]
MAPKs phosphorylate PP2A (Canis familiaris)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Canis familiaris)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Canis familiaris)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
PTEN Regulation (Canis familiaris)
Regulation of PTEN gene transcription (Canis familiaris)
mTORC1 phosphorylates MAF1 (Canis familiaris)
ADP [cytosol]
Regulation of PTEN stability and activity (Canis familiaris)
Casein kinase II phosphorylates PTEN (Canis familiaris)
ADP [cytosol]
FRK phosphorylates PTEN (Canis familiaris)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Canis familiaris)
ADP [cytosol]
MAPK family signaling cascades (Canis familiaris)
MAPK1/MAPK3 signaling (Canis familiaris)
RAF-independent MAPK1/3 activation (Canis familiaris)
MAPK1 (ERK2) activation (Canis familiaris)
MAP2K2 phosphorylates MAPK1 (Canis familiaris)
ADP [cytosol]
RAF/MAP kinase cascade (Canis familiaris)
MAP2K and MAPK activation (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Canis familiaris)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Canis familiaris)
ADP [cytosol]
Negative regulation of MAPK pathway (Canis familiaris)
MAPK12 phosphorylates PTPN3 (Canis familiaris)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Canis familiaris)
Activated MAPK phosphorylates RAF1 (Canis familiaris)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Canis familiaris)
ADP [cytosol]
RAF activation (Canis familiaris)
MARK3 phosphorylates KSR1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of RAF (Canis familiaris)
ADP [cytosol]
RAS processing (Canis familiaris)
KRAS4B is phosphorylated on serine 181 (Canis familiaris)
ADP [cytosol]
MAPK6/MAPK4 signaling (Canis familiaris)
Autophosphorylation of PAK1,2,3 (Canis familiaris)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Canis familiaris)
ADP [cytosol]
MTOR signalling (Canis familiaris)
Energy dependent regulation of mTOR by LKB1-AMPK (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Canis familiaris)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Canis familiaris)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Canis familiaris)
ADP [cytosol]
mTORC1-mediated signalling (Canis familiaris)
Phosphorylation and activation of eIF4B by activated S6K1 (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Canis familiaris)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Canis familiaris)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Canis familiaris)
ADP [cytosol]
Signaling by Erythropoietin (Canis familiaris)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Canis familiaris)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Canis familiaris)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Canis familiaris)
ADP [cytosol]
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Canis familiaris)
ADP [cytosol]
Opioid Signalling (Canis familiaris)
DARPP-32 events (Canis familiaris)
PKA phosphorylates DARPP-32 on Thr34 (Canis familiaris)
ADP [cytosol]
PKA phosphorylates PDE4B (Canis familiaris)
ADP [cytosol]
G-protein mediated events (Canis familiaris)
PLC beta mediated events (Canis familiaris)
Ca-dependent events (Canis familiaris)
CaM pathway (Canis familiaris)
Calmodulin induced events (Canis familiaris)
PKC phosphorylates GRK2 (Canis familiaris)
ADP [cytosol]
phospho-PLA2 pathway (Canis familiaris)
Phosphorylation of cPLA2 by ERK-2 (Canis familiaris)
ADP [cytosol]
G alpha (q) signalling events (Canis familiaris)
Effects of PIP2 hydrolysis (Canis familiaris)
DAG kinase produces phosphatidic acid from DAG (Canis familiaris)
ADP [cytosol]
G alpha (s) signalling events (Canis familiaris)
ADRB2 in ADRB2:GRK complex is phosphorylated (Canis familiaris)
ADP [cytosol]
G-protein beta:gamma signalling (Canis familiaris)
G beta:gamma signalling through PI3Kgamma (Canis familiaris)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Signaling by Hedgehog (Canis familiaris)
Hedgehog 'off' state (Canis familiaris)
GLI3 is processed to GLI3R by the proteasome (Canis familiaris)
CK1 phosphorylates p-GLI3 (Canis familiaris)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Canis familiaris)
ADP [cytosol]
PKA phosphorylates GLI3 (Canis familiaris)
ADP [cytosol]
Hedgehog ligand biogenesis (Canis familiaris)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Canis familiaris)
ADP [cytosol]
Signaling by Hippo (Canis familiaris)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Canis familiaris)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Canis familiaris)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Canis familiaris)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Canis familiaris)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Canis familiaris)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Canis familiaris)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Canis familiaris)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Canis familiaris)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Canis familiaris)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Canis familiaris)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Canis familiaris)
ADP [cytosol]
Signaling by Nuclear Receptors (Canis familiaris)
ESR-mediated signaling (Canis familiaris)
Extra-nuclear estrogen signaling (Canis familiaris)
ESR-associated SRC autophosphorylates (Canis familiaris)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Canis familiaris)
PRKCZ autophosphorylates downstream of estrogen stimulation (Canis familiaris)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Canis familiaris)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by ALK (Canis familiaris)
ALK autophosphorylation (Canis familiaris)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Canis familiaris)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Canis familiaris)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Canis familiaris)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)
ADP [cytosol]
Signaling by EGFR (Canis familiaris)
EGFR autophosphorylation (Canis familiaris)
ADP [cytosol]
EGFR downregulation (Canis familiaris)
EGFR phosphorylates EPS15 (Canis familiaris)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Canis familiaris)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Canis familiaris)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Canis familiaris)
EGFR activates PLC-gamma1 by phosphorylation (Canis familiaris)
ADP [cytosol]
GAB1 signalosome (Canis familiaris)
GAB1 phosphorylation by EGFR kinase (Canis familiaris)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Canis familiaris)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Canis familiaris)
ADP [cytosol]
SHC1 events in EGFR signaling (Canis familiaris)
SHC1 phosphorylation by phosphorylated EGFR (Canis familiaris)
ADP [cytosol]
Signaling by ERBB2 (Canis familiaris)
PI3K events in ERBB2 signaling (Canis familiaris)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Canis familiaris)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Canis familiaris)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Canis familiaris)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Canis familiaris)
Activated PKC phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Canis familiaris)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Canis familiaris)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Canis familiaris)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Canis familiaris)
ADP [cytosol]
Signaling by ERBB4 (Canis familiaris)
PI3K events in ERBB4 signaling (Canis familiaris)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Canis familiaris)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Canis familiaris)
Phosphorylation of SHC1 by ERBB4 homodimers (Canis familiaris)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Canis familiaris)
ADP [cytosol]
Signaling by FGFR (Canis familiaris)
Signaling by FGFR1 (Canis familiaris)
Downstream signaling of activated FGFR1 (Canis familiaris)
FRS-mediated FGFR1 signaling (Canis familiaris)
Activated FGFR1 phosphorylates FRS2 (Canis familiaris)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Canis familiaris)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Canis familiaris)
ADP [cytosol]
PI-3K cascade:FGFR1 (Canis familiaris)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Canis familiaris)
Activated FGFR1 phosphorylates PLCG1 (Canis familiaris)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Canis familiaris)
Activated FGFR1 phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
FGFR1 ligand binding and activation (Canis familiaris)
FGFR1b ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR1b (Canis familiaris)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Canis familiaris)
ADP [cytosol]
FGFR1c ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR1c (Canis familiaris)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Canis familiaris)
ADP [cytosol]
Spry regulation of FGF signaling (Canis familiaris)
SPRY2 is phosphorylated by phosphorylated MNK1 (Canis familiaris)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Canis familiaris)
ADP [cytosol]
Signaling by FGFR2 (Canis familiaris)
Downstream signaling of activated FGFR2 (Canis familiaris)
FRS-mediated FGFR2 signaling (Canis familiaris)
Activated FGFR2 phosphorylates FRS2 (Canis familiaris)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Canis familiaris)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Canis familiaris)
ADP [cytosol]
PI-3K cascade:FGFR2 (Canis familiaris)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Canis familiaris)
Activated FGFR2 phosphorylates PLCG1 (Canis familiaris)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Canis familiaris)
Activated FGFR2 phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
FGFR2 ligand binding and activation (Canis familiaris)
FGFR2b ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR2b (Canis familiaris)
ADP [cytosol]
FGFR2c ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR2c (Canis familiaris)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Canis familiaris)
ADP [cytosol]
Spry regulation of FGF signaling (Canis familiaris)
SPRY2 is phosphorylated by phosphorylated MNK1 (Canis familiaris)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Canis familiaris)
ADP [cytosol]
Signaling by FGFR3 (Canis familiaris)
Downstream signaling of activated FGFR3 (Canis familiaris)
FRS-mediated FGFR3 signaling (Canis familiaris)
Activated FGFR3 phosphorylates FRS2 (Canis familiaris)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Canis familiaris)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Canis familiaris)
ADP [cytosol]
PI-3K cascade:FGFR3 (Canis familiaris)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Canis familiaris)
Activated FGFR3 phosphorylates PLCG1 (Canis familiaris)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Canis familiaris)
Activated FGFR3 phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
FGFR3 ligand binding and activation (Canis familiaris)
FGFR3b ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR3b (Canis familiaris)
ADP [cytosol]
FGFR3c ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR3c (Canis familiaris)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Canis familiaris)
ADP [cytosol]
Spry regulation of FGF signaling (Canis familiaris)
SPRY2 is phosphorylated by phosphorylated MNK1 (Canis familiaris)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Canis familiaris)
ADP [cytosol]
Signaling by FGFR4 (Canis familiaris)
Downstream signaling of activated FGFR4 (Canis familiaris)
FRS-mediated FGFR4 signaling (Canis familiaris)
Activated FGFR4 phosphorylates FRS2 (Canis familiaris)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Canis familiaris)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Canis familiaris)
ADP [cytosol]
PI-3K cascade:FGFR4 (Canis familiaris)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Canis familiaris)
Activated FGFR4 phosphorylates PLCG1 (Canis familiaris)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Canis familiaris)
Activated FGFR4 phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
FGFR4 ligand binding and activation (Canis familiaris)
Autocatalytic phosphorylation of FGFR4 (Canis familiaris)
ADP [cytosol]
betaKlotho-mediated ligand binding (Canis familiaris)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Canis familiaris)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Canis familiaris)
ADP [cytosol]
Spry regulation of FGF signaling (Canis familiaris)
SPRY2 is phosphorylated by phosphorylated MNK1 (Canis familiaris)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Canis familiaris)
ADP [cytosol]
Signaling by Insulin receptor (Canis familiaris)
Autophosphorylation of insulin receptor (Canis familiaris)
ADP [cytosol]
Insulin receptor signalling cascade (Canis familiaris)
IRS activation (Canis familiaris)
Phosphorylation of IRS (Canis familiaris)
ADP [cytosol]
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of SHC1 (Canis familiaris)
ADP [cytosol]
Signal attenuation (Canis familiaris)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Canis familiaris)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Canis familiaris)
ADP [cytosol]
Signaling by MET (Canis familiaris)
MET Receptor Activation (Canis familiaris)
MET dimers autophosphorylate (Canis familiaris)
ADP [cytosol]
MET activates PI3K/AKT signaling (Canis familiaris)
MET bound PI3K generates PIP3 (Canis familiaris)
ADP [cytosol]
MET phosphorylates GAB1 (Canis familiaris)
ADP [cytosol]
MET activates RAS signaling (Canis familiaris)
MET phosphorylates SHC1-2 (Canis familiaris)
ADP [cytosol]
MET activates STAT3 (Canis familiaris)
MET phosphorylates STAT3 (Canis familiaris)
ADP [cytosol]
MET promotes cell motility (Canis familiaris)
MET activates PTK2 signaling (Canis familiaris)
MET phosphorylates PTK2 (Canis familiaris)
ADP [cytosol]
PTK2 autophosphorylates (Canis familiaris)
ADP [cytosol]
SRC phosphorylates PTK2 (Canis familiaris)
ADP [cytosol]
Negative regulation of MET activity (Canis familiaris)
MET phosphorylates CBL (Canis familiaris)
ADP [cytosol]
Signaling by MST1 (Canis familiaris)
MST1R autophosphorylates (Canis familiaris)
ADP [cytosol]
Signaling by NTRKs (Canis familiaris)
Signaling by NTRK1 (TRKA) (Canis familiaris)
PI3K/AKT activation (Canis familiaris)
PI3K produces PIP3 and other phosphatidyl inositides (Canis familiaris)
ADP [cytosol]
Signalling to ERKs (Canis familiaris)
Prolonged ERK activation events (Canis familiaris)
ARMS-mediated activation (Canis familiaris)
ARMS is phosphorylated by active TrkA receptor (Canis familiaris)
ADP [cytosol]
Frs2-mediated activation (Canis familiaris)
FRS2 is phosphorylated by active TrkA receptor (Canis familiaris)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Canis familiaris)
Activated NTRK3 signals through PI3K (Canis familiaris)
Activated NTRK3 promotes SRC autophosphorylation (Canis familiaris)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Canis familiaris)
NTRK3 dimers trans-autophosphorylate (Canis familiaris)
ADP [cytosol]
Signaling by PDGF (Canis familiaris)
Autophosphorylation of PDGF alpha receptors (Canis familiaris)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Canis familiaris)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Canis familiaris)
ADP [cytosol]
Downstream signal transduction (Canis familiaris)
Activation of Src (Canis familiaris)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Canis familiaris)
ADP [cytosol]
Signaling by SCF-KIT (Canis familiaris)
Autophosphorylation of KIT (Canis familiaris)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Canis familiaris)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Canis familiaris)
ADP [cytosol]
Phosphorylation of JAK2 (Canis familiaris)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Canis familiaris)
ADP [cytosol]
Phosphorylation of STATs (Canis familiaris)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Canis familiaris)
ADP [cytosol]
Regulation of KIT signaling (Canis familiaris)
PKC alpha interacts with and phosphorylates KIT (Canis familiaris)
ADP [cytosol]
Phosphorylation of APS (Canis familiaris)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1,2:IGF1R autophosphorylates (Canis familiaris)
ADP [cytosol]
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Canis familiaris)
ADP [cytosol]
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
SHC-related events triggered by IGF1R (Canis familiaris)
IGF1R phosphorylates SHC1 (Canis familiaris)
ADP [cytosol]
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
AXL autophosphorylates on Y779 and Y821 (Canis familiaris)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Canis familiaris)
ADP [cytosol]
FYN autophosphorylates (Canis familiaris)
ADP [cytosol]
FYN phosphorylates PAK2 (Canis familiaris)
ADP [cytosol]
PAK2 autophorylates (Canis familiaris)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Canis familiaris)
ADP [cytosol]
PTK2 autophosphorylates (Canis familiaris)
ADP [cytosol]
Phosphorylation of SRC-1 (Canis familiaris)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Canis familiaris)
ADP [cytosol]
SRC-1 phosphorylates SHB (Canis familiaris)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Canis familiaris)
ADP [cytosol]
Src kinases phosphorylate VAV (Canis familiaris)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
ADP [cytosol]
VEGFR2 autophosphorylates (Canis familiaris)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Canis familiaris)
PDK1 phosphorylates PKC (Canis familiaris)
ADP [cytosol]
PKC autophosphorylates (Canis familiaris)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Canis familiaris)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Canis familiaris)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Canis familiaris)
PAK1-3 autophosphorylates (Canis familiaris)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Canis familiaris)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Canis familiaris)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Canis familiaris)
ADP [cytosol]
p38 MAPK activation by VEGFR (Canis familiaris)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
RHOBTB3 ATPase cycle (Canis familiaris)
RHOBTB3 hydrolyzes ATP (Canis familiaris)
RHOBTB3:ADP [trans-Golgi network membrane] (Canis familiaris)
ADP [cytosol]
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate Formins (Canis familiaris)
AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Canis familiaris)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Canis familiaris)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Canis familiaris)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Canis familiaris)
ADP [cytosol]
PKC phosphorylates NCF1 (Canis familiaris)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Canis familiaris)
ABL phosphorylates WAVEs (Canis familiaris)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Canis familiaris)
Mother filament:ARP2/3:actin:ADP [cytosol] (Canis familiaris)
Actin:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Detachment of WASP/WAVE (Canis familiaris)
Mother filament:ARP2/3:actin:ADP [cytosol] (Canis familiaris)
Actin:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Canis familiaris)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Canis familiaris)
ADP [cytosol]
RHO GTPases activate PAKs (Canis familiaris)
Autophosphorylation of PAK1,2,3 (Canis familiaris)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Canis familiaris)
ADP [cytosol]
PAK1 phosphorylates FLNA (Canis familiaris)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Canis familiaris)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Canis familiaris)
ADP [cytosol]
RHO GTPases activate PKNs (Canis familiaris)
PDPK1 phosphorylates PKN1,2,3 (Canis familiaris)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Canis familiaris)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Canis familiaris)
ADP [cytosol]
Signaling by TGFB family members (Canis familiaris)
Signaling by Activin (Canis familiaris)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Canis familiaris)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Canis familiaris)
ADP [cytosol]
Signaling by BMP (Canis familiaris)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Canis familiaris)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Canis familiaris)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Canis familiaris)
TGF-beta receptor signaling activates SMADs (Canis familiaris)
Activated type I receptor phosphorylates SMAD2/3 directly (Canis familiaris)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Canis familiaris)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Canis familiaris)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Canis familiaris)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)
ADP [cytosol]
Signaling by WNT (Canis familiaris)
Beta-catenin independent WNT signaling (Canis familiaris)
Ca2+ pathway (Canis familiaris)
Activation of NLK (Canis familiaris)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Canis familiaris)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Canis familiaris)
ADP [cytosol]
PCP/CE pathway (Canis familiaris)
WNT5A-dependent internalization of FZD4 (Canis familiaris)
DVL2 is phosphorylated by PKC (Canis familiaris)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Canis familiaris)
AXIN is phosphorylated in the destruction complex (Canis familiaris)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Canis familiaris)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Canis familiaris)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Canis familiaris)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Canis familiaris)
ADP [cytosol]
TCF dependent signaling in response to WNT (Canis familiaris)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Canis familiaris)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)
ADP [cytosol]
WNT mediated activation of DVL (Canis familiaris)
CSNK2-mediated phosphorylation of DVL (Canis familiaris)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Canis familiaris)
ADP [cytosol]
Transport of small molecules (Canis familiaris)
ABC-family proteins mediated transport (Canis familiaris)
ABC transporters in lipid homeostasis (Canis familiaris)
ABCA12 transports lipids from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Canis familiaris)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Canis familiaris)
ADP [cytosol]
ABCA7:Apo1A-mediated phospholipid efflux (Canis familiaris)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Canis familiaris)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Canis familiaris)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCA4 mediates atRAL transport (Canis familiaris)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Canis familiaris)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Canis familiaris)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
HCO3- transport through ion channel (Canis familiaris)
ADP [cytosol]
Mitochondrial ABC transporters (Canis familiaris)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Canis familiaris)
ADP [cytosol]
The ABCC family mediates organic anion transport (Canis familiaris)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Canis familiaris)
ADP [cytosol]
Aquaporin-mediated transport (Canis familiaris)
Vasopressin regulates renal water homeostasis via Aquaporins (Canis familiaris)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Canis familiaris)
ADP [cytosol]
Ion channel transport (Canis familiaris)
Ion transport by P-type ATPases (Canis familiaris)
ATP12A:ATP4B exchanges K+ for H+ (Canis familiaris)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Canis familiaris)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Canis familiaris)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Canis familiaris)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Canis familiaris)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Canis familiaris)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Canis familiaris)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Canis familiaris)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Canis familiaris)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Canis familiaris)
ADP [cytosol]
Stimuli-sensing channels (Canis familiaris)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Canis familiaris)
ADP [cytosol]
Iron uptake and transport (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
ADP [cytosol]
Transferrin endocytosis and recycling (Canis familiaris)
Acidification of Tf:TfR1 containing endosome (Canis familiaris)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Canis familiaris)
Plasma lipoprotein assembly (Canis familiaris)
HDL assembly (Canis familiaris)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Canis familiaris)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Canis familiaris)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Canis familiaris)
ADP [cytosol]
Plasma lipoprotein remodeling (Canis familiaris)
HDL remodeling (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
ADP [cytosol]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
ADP [cytosol]
Vesicle-mediated transport (Canis familiaris)
Membrane Trafficking (Canis familiaris)
Clathrin-mediated endocytosis (Canis familiaris)
AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Canis familiaris)
ADBRK1,2 phosphorylate AVPR2 (Canis familiaris)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Canis familiaris)
clathrin:HSPA8:ADP [cytosol] (Canis familiaris)
HSPA8:ADP [cytosol] (Canis familiaris)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Canis familiaris)
ADP [cytosol]
ER to Golgi Anterograde Transport (Canis familiaris)
COPI-mediated anterograde transport (Canis familiaris)
GBF1 stimulates ARF nucleotide exchange (Canis familiaris)
ADP [cytosol]
COPII-mediated vesicle transport (Canis familiaris)
CSNK1D phosphorylates SEC23 (Canis familiaris)
ADP [cytosol]
Gap junction trafficking and regulation (Canis familiaris)
Regulation of gap junction activity (Canis familiaris)
Phosphorylation of Cx43 by c-src (Canis familiaris)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Canis familiaris)
Intra-Golgi traffic (Canis familiaris)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Canis familiaris)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Canis familiaris)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Canis familiaris)
ADP [cytosol]
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Canis familiaris)
RHOBTB3:ADP [trans-Golgi network membrane] (Canis familiaris)
ADP [cytosol]
Rab regulation of trafficking (Canis familiaris)
RAB GEFs exchange GTP for GDP on RABs (Canis familiaris)
p-ULK1 phosphorylates DENND3 (Canis familiaris)
ADP [cytosol]
trans-Golgi Network Vesicle Budding (Canis familiaris)
Golgi Associated Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
ADP [cytosol]
Lysosome Vesicle Biogenesis (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
ADP [cytosol]
Autophagy (Danio rerio)
Macroautophagy (Danio rerio)
Active MTORC1 phosphorylates ULK1 (Danio rerio)
ADP [cytosol]
Selective autophagy (Danio rerio)
Mitophagy (Danio rerio)
Receptor Mediated Mitophagy (Danio rerio)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Danio rerio)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Danio rerio)
ADP [cytosol]
Cell Cycle (Danio rerio)
Cell Cycle Checkpoints (Danio rerio)
G2/M Checkpoints (Danio rerio)
G2/M DNA replication checkpoint (Danio rerio)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Danio rerio)
ADP [cytosol]
Cell Cycle, Mitotic (Danio rerio)
M Phase (Danio rerio)
Mitotic Metaphase and Anaphase (Danio rerio)
Mitotic Anaphase (Danio rerio)
Nuclear Envelope (NE) Reassembly (Danio rerio)
Initiation of Nuclear Envelope (NE) Reformation (Danio rerio)
CDK1 phosphorylates LBR (Danio rerio)
ADP [cytosol]
Mitotic Prometaphase (Danio rerio)
EML4 and NUDC in mitotic spindle formation (Danio rerio)
PLK1 phosphorylates NUDC (Danio rerio)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Danio rerio)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Danio rerio)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Danio rerio)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Danio rerio)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Danio rerio)
ADP [cytosol]
Mitotic Prophase (Danio rerio)
Golgi Cisternae Pericentriolar Stack Reorganization (Danio rerio)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Danio rerio)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Danio rerio)
G1 Phase (Danio rerio)
Cyclin D associated events in G1 (Danio rerio)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Danio rerio)
ADP [cytosol]
G1/S Transition (Danio rerio)
Cyclin E associated events during G1/S transition (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Danio rerio)
PTK6 phosphorylates CDKN1B (Danio rerio)
ADP [cytosol]
Mitotic G2-G2/M phases (Danio rerio)
G2/M Transition (Danio rerio)
Cyclin A/B1/B2 associated events during G2/M transition (Danio rerio)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Danio rerio)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Danio rerio)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Danio rerio)
AURKA phosphorylates PHLDA1 (Danio rerio)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Danio rerio)
CDK1 phosphorylates BORA (Danio rerio)
ADP [cytosol]
PLK1 phosphorylates BORA (Danio rerio)
ADP [cytosol]
PLK1 phosphorylates OPTN (Danio rerio)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Danio rerio)
PLK1 phosphorylates GTSE1 (Danio rerio)
ADP [cytosol]
S Phase (Danio rerio)
Cyclin A:Cdk2-associated events at S phase entry (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Danio rerio)
PTK6 phosphorylates CDKN1B (Danio rerio)
ADP [cytosol]
Cell-Cell communication (Danio rerio)
Nephrin family interactions (Danio rerio)
Phosphorylation of nephrin by FYN (Danio rerio)
ADP [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular Senescence (Danio rerio)
Oxidative Stress Induced Senescence (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Cellular response to chemical stress (Danio rerio)
KEAP1-NFE2L2 pathway (Danio rerio)
PRKCI phosphorylates NFE2L2 (Danio rerio)
ADP [cytosol]
Cellular response to heat stress (Danio rerio)
Regulation of HSF1-mediated heat shock response (Danio rerio)
HSP110s exchange ATP for ADP on HSP70s:ADP (Danio rerio)
ADP [cytosol]
HSP70s:ADP [cytosol] (Danio rerio)
HSP13:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSP14:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA2:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA4:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA5:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA6:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA8:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA9:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Danio rerio)
HSP70s:ADP [cytosol] (Danio rerio)
HSP13:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSP14:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA2:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA4:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA5:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA6:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA8:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSPA9:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Danio rerio)
ATP binding to HSP90 triggers conformation change (Danio rerio)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Danio rerio)
HSP70:ADP [cytosol] (Danio rerio)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Danio rerio)
HSP70:ADP:nascent protein [cytosol] (Danio rerio)
HSP70:ADP [cytosol] (Danio rerio)
ADP [cytosol]
ATP hydrolysis by HSP70 (Danio rerio)
HSP40:HSP70:ADP:nascent protein [cytosol] (Danio rerio)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Danio rerio)
HSP40:HSP70:ADP:nascent protein [cytosol] (Danio rerio)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Danio rerio)
HSP70:ADP:nascent protein [cytosol] (Danio rerio)
HSP70:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Developmental Biology (Danio rerio)
Nervous system development (Danio rerio)
Axon guidance (Danio rerio)
EPH-Ephrin signaling (Danio rerio)
EPH receptors autophosphorylate (Danio rerio)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Danio rerio)
SFKs phosphorylate VAV2,3 (Danio rerio)
ADP [cytosol]
EPHB-mediated forward signaling (Danio rerio)
p-EPHB phosphorylates SDC2 (Danio rerio)
ADP [cytosol]
L1CAM interactions (Danio rerio)
Signal transduction by L1 (Danio rerio)
MAP2K1 phosphorylates MAPK3 (Danio rerio)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Danio rerio)
ADP [cytosol]
Netrin-1 signaling (Danio rerio)
DCC mediated attractive signaling (Danio rerio)
Phosphorylation of DCC by Fyn (Danio rerio)
ADP [cytosol]
Semaphorin interactions (Danio rerio)
CRMPs in Sema3A signaling (Danio rerio)
Phosphorylation of CRMPs by Cdk5 (Danio rerio)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Danio rerio)
Autophosphorylation of PAK (Danio rerio)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Danio rerio)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Danio rerio)
ADP [cytosol]
Drug ADME (Danio rerio)
Aspirin ADME (Danio rerio)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Danio rerio)
ADP [cytosol]
Azathioprine ADME (Danio rerio)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Danio rerio)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Danio rerio)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Danio rerio)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Danio rerio)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Danio rerio)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Danio rerio)
ADP [cytosol]
Paracetamol ADME (Danio rerio)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Danio rerio)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Danio rerio)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Danio rerio)
ADP [cytosol]
Ribavirin ADME (Danio rerio)
ADK phosphorylates RBV (Danio rerio)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Danio rerio)
ADP [cytosol]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
Regulation of TP53 Activity (Danio rerio)
Regulation of TP53 Expression and Degradation (Danio rerio)
Regulation of TP53 Degradation (Danio rerio)
AKT phosphorylates MDM2 (Danio rerio)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Danio rerio)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Danio rerio)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Danio rerio)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Danio rerio)
PLK2 phosphorylates CENPJ (Danio rerio)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Danio rerio)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Danio rerio)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Danio rerio)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Danio rerio)
Regulation of RUNX3 expression and activity (Danio rerio)
SRC phosphorylates RUNX3 (Danio rerio)
ADP [cytosol]
Hemostasis (Danio rerio)
Factors involved in megakaryocyte development and platelet production (Danio rerio)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Danio rerio)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Danio rerio)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Danio rerio)
ADP [cytosol]
Platelet activation, signaling and aggregation (Danio rerio)
GPVI-mediated activation cascade (Danio rerio)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Danio rerio)
Integrin signaling (Danio rerio)
Autophosphorylation of SRC (Danio rerio)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Danio rerio)
Disinhibition of SNARE formation (Danio rerio)
Phosphorylation of Syntaxin-4 (Danio rerio)
ADP [cytosol]
Platelet degranulation (Danio rerio)
ABCC4 accumulation of dense granule contents (Danio rerio)
ADP [cytosol]
Signal amplification (Danio rerio)
ADP signalling through P2Y purinoceptor 1 (Danio rerio)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Danio rerio)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Danio rerio)
ADP [cytosol]
Platelet homeostasis (Danio rerio)
Platelet sensitization by LDL (Danio rerio)
Fgr may phosphorylate p38 MAPK (Danio rerio)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Danio rerio)
ADP [cytosol]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Rap1 signalling (Danio rerio)
PKA/PKG phosphorylate Rap1GAP2 (Danio rerio)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Danio rerio)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Danio rerio)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Danio rerio)
ADP [cytosol]
Cytokine Signaling in Immune system (Danio rerio)
Growth hormone receptor signaling (Danio rerio)
JAK2 phosphorylation (Danio rerio)
ADP [cytosol]
JAK2 phosphorylation of GHR (Danio rerio)
ADP [cytosol]
Lyn activates ERK (Danio rerio)
ADP [cytosol]
Interferon Signaling (Danio rerio)
Antiviral mechanism by IFN-stimulated genes (Danio rerio)
PKR-mediated signaling (Danio rerio)
p-PKR dimer phosphorylates CDK1 (Danio rerio)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Danio rerio)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Danio rerio)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Danio rerio)
ADP [cytosol]
Interferon gamma signaling (Danio rerio)
JAK2-activated MAPKs phosphorylate YBX1 (Danio rerio)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Danio rerio)
ADP [cytosol]
Phosphorylation of JAK2 (Danio rerio)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Danio rerio)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Danio rerio)
ADP [cytosol]
Transphosphorylation of JAK1 (Danio rerio)
ADP [cytosol]
Prolactin receptor signaling (Danio rerio)
JAK2 phosphorylation (Danio rerio)
ADP [cytosol]
Signaling by Interleukins (Danio rerio)
Interleukin-1 family signaling (Danio rerio)
Interleukin-37 signaling (Danio rerio)
TBK1 phosphorylation (Danio rerio)
ADP [cytosol]
Interleukin-38 signaling (Danio rerio)
MAPK8 phosphorylation (Danio rerio)
ADP [cytosol]
Interleukin-10 signaling (Danio rerio)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Danio rerio)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)
ADP [cytosol]
Interleukin-17 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Interleukin-2 family signaling (Danio rerio)
Interleukin-21 signaling (Danio rerio)
IL21 receptor JAK phosphorylation (Danio rerio)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Danio rerio)
ADP [cytosol]
Interleukin-20 family signaling (Danio rerio)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Danio rerio)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Danio rerio)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Danio rerio)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Danio rerio)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Danio rerio)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Danio rerio)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Danio rerio)
ADP [cytosol]
Interleukin-6 family signaling (Danio rerio)
Interleukin-6 signaling (Danio rerio)
IL6ST is tyrosine phosphorylated (Danio rerio)
ADP [cytosol]
JAK activation (Danio rerio)
ADP [cytosol]
PTPN11 is phosphorylated (Danio rerio)
ADP [cytosol]
Serine phosphorylation of STATs (Danio rerio)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Danio rerio)
ADP [cytosol]
Innate Immune System (Danio rerio)
Antimicrobial peptides (Danio rerio)
Ion influx/efflux at host-pathogen interface (Danio rerio)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Danio rerio)
ADP [cytosol]
C-type lectin receptors (CLRs) (Danio rerio)
Dectin-2 family (Danio rerio)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Danio rerio)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Danio rerio)
STING mediated induction of host immune responses (Danio rerio)
STAT6-mediated induction of chemokines (Danio rerio)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Danio rerio)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Danio rerio)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Danio rerio)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Danio rerio)
FCERI mediated MAPK activation (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Danio rerio)
Regulation of actin dynamics for phagocytic cup formation (Danio rerio)
Branching and elongation of mother and daughter filaments (Danio rerio)
Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
Actin:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Detachment of WASP/WAVE (Danio rerio)
Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
Actin:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Danio rerio)
ADP [cytosol]
Role of phospholipids in phagocytosis (Danio rerio)
DAG stimulates protein kinase C-delta (Danio rerio)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Danio rerio)
NOD1/2 Signaling Pathway (Danio rerio)
Activation of p38 MAPK (Danio rerio)
ADP [cytosol]
Toll-like Receptor Cascades (Danio rerio)
Toll Like Receptor 10 (TLR10) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Danio rerio)
Toll Like Receptor TLR1:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Danio rerio)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Danio rerio)
MyD88-independent TLR4 cascade (Danio rerio)
TRIF (TICAM1)-mediated TLR4 signaling (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Danio rerio)
MyD88 cascade initiated on plasma membrane (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Danio rerio)
MyD88 dependent cascade initiated on endosome (Danio rerio)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Danio rerio)
MAP kinase activation (Danio rerio)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
ADP [cytosol]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Pyruvate metabolism (Danio rerio)
PKM dephosphorylates PEP to PYR (Danio rerio)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Danio rerio)
Mitochondrial Uncoupling (Danio rerio)
The proton buffering model (Danio rerio)
Protons are translocated from the intermembrane space to the matrix (Danio rerio)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Danio rerio)
Phase II - Conjugation of compounds (Danio rerio)
Cytosolic sulfonation of small molecules (Danio rerio)
Transport and synthesis of PAPS (Danio rerio)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Danio rerio)
ADP [cytosol]
Glutathione conjugation (Danio rerio)
Glutathione synthesis and recycling (Danio rerio)
GSS:Mg2+ dimer synthesizes GSH (Danio rerio)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Danio rerio)
ADP [cytosol]
Inositol phosphate metabolism (Danio rerio)
Synthesis of IP3 and IP4 in the cytosol (Danio rerio)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Danio rerio)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Danio rerio)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Danio rerio)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Danio rerio)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Danio rerio)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Danio rerio)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Danio rerio)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Danio rerio)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Danio rerio)
ADP [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Creatine metabolism (Danio rerio)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Danio rerio)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Danio rerio)
ADP [cytosol]
Glutamate and glutamine metabolism (Danio rerio)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Danio rerio)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Danio rerio)
ADP [cytosol]
Metabolism of carbohydrates (Danio rerio)
Formation of xylulose-5-phosphate (Danio rerio)
XYLB phosphorylates D-xylulose (Danio rerio)
ADP [cytosol]
Fructose metabolism (Danio rerio)
Fructose catabolism (Danio rerio)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Danio rerio)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Danio rerio)
ADP [cytosol]
Galactose catabolism (Danio rerio)
GALK1 phosphorylates Gal to Gal1P (Danio rerio)
ADP [cytosol]
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Danio rerio)
ADP [cytosol]
Glycolysis (Danio rerio)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Danio rerio)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Danio rerio)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Danio rerio)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Danio rerio)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Danio rerio)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Danio rerio)
ADP [cytosol]
Glycosaminoglycan metabolism (Danio rerio)
Transport and synthesis of PAPS (Danio rerio)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Danio rerio)
ADP [cytosol]
Pentose phosphate pathway (Danio rerio)
RBKS phosphorylates ribose to R5P (Danio rerio)
ADP [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Arachidonic acid metabolism (Danio rerio)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Danio rerio)
ALOX5 is phosphorylated by MAPKAP2 (Danio rerio)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Danio rerio)
ACLY tetramer transforms CIT to Ac-CoA (Danio rerio)
ADP [cytosol]
Metabolism of steroids (Danio rerio)
Cholesterol biosynthesis (Danio rerio)
MVD decarboxylates MVA5PP to IPPP (Danio rerio)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Danio rerio)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Danio rerio)
ADP [cytosol]
Phospholipid metabolism (Danio rerio)
Glycerophospholipid biosynthesis (Danio rerio)
Synthesis of PC (Danio rerio)
Cho is phosphorylated to PCho by CHK dimer (Danio rerio)
ADP [cytosol]
Synthesis of PE (Danio rerio)
ETA is phosphorylated to PETA by CHK/ETNK (Danio rerio)
ADP [cytosol]
PI Metabolism (Danio rerio)
Synthesis of PIPs at the ER membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Danio rerio)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Danio rerio)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Danio rerio)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Danio rerio)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Danio rerio)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Danio rerio)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Danio rerio)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Danio rerio)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Danio rerio)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Danio rerio)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Danio rerio)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Danio rerio)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Danio rerio)
ADP [cytosol]
Sphingolipid metabolism (Danio rerio)
Sphingolipid de novo biosynthesis (Danio rerio)
CSNK1G2 phosphorylates p-CERT1-2 (Danio rerio)
ADP [cytosol]
PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)
ADP [cytosol]
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Danio rerio)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Danio rerio)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Danio rerio)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Danio rerio)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Danio rerio)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Danio rerio)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Danio rerio)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Danio rerio)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Danio rerio)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Danio rerio)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Danio rerio)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Danio rerio)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Danio rerio)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Danio rerio)
ADP [cytosol]
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Danio rerio)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Danio rerio)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Danio rerio)
ADP [cytosol]
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Danio rerio)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Danio rerio)
ADP [cytosol]
Pyrimidine catabolism (Danio rerio)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Danio rerio)
ADP [cytosol]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Danio rerio)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Danio rerio)
ADP [cytosol]
Pyrimidine salvage (Danio rerio)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Danio rerio)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Danio rerio)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Danio rerio)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Danio rerio)
ADP [cytosol]
Metabolism of porphyrins (Danio rerio)
Heme degradation (Danio rerio)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Danio rerio)
ADP [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Metabolism of folate and pterines (Danio rerio)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Danio rerio)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Danio rerio)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Danio rerio)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Danio rerio)
ADP [cytosol]
Nicotinate metabolism (Danio rerio)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Danio rerio)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Danio rerio)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Danio rerio)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Danio rerio)
Coenzyme A biosynthesis (Danio rerio)
COASY phosphorylates DP-CoA (Danio rerio)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Danio rerio)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Danio rerio)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Danio rerio)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Danio rerio)
2xPDKX:2xZn2+ phosphorylates PDX (Danio rerio)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Danio rerio)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Danio rerio)
ADP [cytosol]
Metabolism of RNA (Danio rerio)
Nonsense-Mediated Decay (NMD) (Danio rerio)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Danio rerio)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Danio rerio)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Danio rerio)
MK2 phosphorylates BRF1 (Danio rerio)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Danio rerio)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Danio rerio)
Protein Kinase B (AKT) phosphorylates KSRP (Danio rerio)
ADP [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
Synthesis of substrates in N-glycan biosythesis (Danio rerio)
Sialic acid metabolism (Danio rerio)
GNE phosphorylates ManNAc to ManNAc-6-P (Danio rerio)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Danio rerio)
MVD decarboxylates MVA5PP to IPPP (Danio rerio)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPI-mediated anterograde transport (Danio rerio)
GBF1 stimulates ARF nucleotide exchange (Danio rerio)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Danio rerio)
FN3K phosphorylates ketosamines (Danio rerio)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Danio rerio)
ADP [cytosol]
Protein folding (Danio rerio)
Chaperonin-mediated protein folding (Danio rerio)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Danio rerio)
ATP binds G-protein beta associated TRiC/CCT (Danio rerio)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Danio rerio)
CCT/TRiC:ADP [cytosol] (Danio rerio)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Danio rerio)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Danio rerio)
CCT/TRiC:ADP [cytosol] (Danio rerio)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Danio rerio)
CCT/TRiC:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Danio rerio)
CCT/TRiC:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Translation (Danio rerio)
Eukaryotic Translation Initiation (Danio rerio)
Cap-dependent Translation Initiation (Danio rerio)
Ribosomal scanning and start codon recognition (Danio rerio)
Ribosomal scanning (Danio rerio)
ADP [cytosol]
Muscle contraction (Danio rerio)
Cardiac conduction (Danio rerio)
Ion homeostasis (Danio rerio)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Danio rerio)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Danio rerio)
ADP [cytosol]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter uptake and metabolism In glial cells (Danio rerio)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Danio rerio)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Danio rerio)
ADP [cytosol]
Programmed Cell Death (Danio rerio)
Apoptosis (Danio rerio)
Intrinsic Pathway for Apoptosis (Danio rerio)
Apoptotic factor-mediated response (Danio rerio)
Cytochrome c-mediated apoptotic response (Danio rerio)
Activation of caspases through apoptosome-mediated cleavage (Danio rerio)
Cleavage of Procaspase-3 by the apoptosome (Danio rerio)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Danio rerio)
ADP [cytosol]
Formation of apoptosome (Danio rerio)
CYCS binds to APAF1 (Danio rerio)
ADP [cytosol]
APAF1:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Danio rerio)
ADP [cytosol]
Regulation of the apoptosome activity (Danio rerio)
CASP9 is phosphorylated at T412 (Danio rerio)
ADP [cytosol]
Sensory Perception (Danio rerio)
Visual phototransduction (Danio rerio)
The phototransduction cascade (Danio rerio)
Inactivation, recovery and regulation of the phototransduction cascade (Danio rerio)
GRK1,4,7 phosphorylate MII to p-MII (Danio rerio)
ADP [cytosol]
Signal Transduction (Danio rerio)
Death Receptor Signaling (Danio rerio)
p75 NTR receptor-mediated signalling (Danio rerio)
Cell death signalling via NRAGE, NRIF and NADE (Danio rerio)
NRAGE signals death through JNK (Danio rerio)
GTP-bound RAC contributes to JNK activation (Danio rerio)
ADP [cytosol]
Integrin signaling (Danio rerio)
Autophosphorylation of SRC (Danio rerio)
ADP [cytosol]
Intracellular signaling by second messengers (Danio rerio)
DAG and IP3 signaling (Danio rerio)
DAG stimulates protein kinase C-delta (Danio rerio)
ADP [cytosol]
PIP3 activates AKT signaling (Danio rerio)
AKT phosphorylates targets in the cytosol (Danio rerio)
AKT phosphorylates IKKalpha (Danio rerio)
ADP [cytosol]
AKT phosphorylates MDM2 (Danio rerio)
ADP [cytosol]
AKT phosphorylates MKRN1 (Danio rerio)
ADP [cytosol]
AKT phosphorylates caspase-9 (Danio rerio)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Danio rerio)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Danio rerio)
MAPKs phosphorylate PP2A (Danio rerio)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Danio rerio)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Danio rerio)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Danio rerio)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
PTEN Regulation (Danio rerio)
Regulation of PTEN gene transcription (Danio rerio)
mTORC1 phosphorylates MAF1 (Danio rerio)
ADP [cytosol]
Regulation of PTEN stability and activity (Danio rerio)
AKT phosphorylates MKRN1 (Danio rerio)
ADP [cytosol]
MAPK family signaling cascades (Danio rerio)
MAPK1/MAPK3 signaling (Danio rerio)
RAF-independent MAPK1/3 activation (Danio rerio)
MAPK1 (ERK2) activation (Danio rerio)
MAP2K2 phosphorylates MAPK1 (Danio rerio)
ADP [cytosol]
MAPK3 (ERK1) activation (Danio rerio)
Inactivation of MAP2K1 by CDK1 (Danio rerio)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Danio rerio)
ADP [cytosol]
RAF/MAP kinase cascade (Danio rerio)
MAP2K and MAPK activation (Danio rerio)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Danio rerio)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Danio rerio)
ADP [cytosol]
Negative regulation of MAPK pathway (Danio rerio)
Negative feedback regulation of MAPK pathway (Danio rerio)
Activated MAPKs phosphorylate MAP2K1 (Danio rerio)
ADP [cytosol]
MAPK6/MAPK4 signaling (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Danio rerio)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Danio rerio)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Danio rerio)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Danio rerio)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Danio rerio)
ADP [cytosol]
MTOR signalling (Danio rerio)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Danio rerio)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Danio rerio)
AMPK phosphorylates Raptor in the mTORC1 complex (Danio rerio)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Danio rerio)
ADP [cytosol]
mTORC1-mediated signalling (Danio rerio)
Phosphorylation of 4E-BP1 by activated mTORC1 (Danio rerio)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Danio rerio)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Danio rerio)
ADP [cytosol]
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Danio rerio)
ADP [cytosol]
Opioid Signalling (Danio rerio)
G-protein mediated events (Danio rerio)
PLC beta mediated events (Danio rerio)
Ca-dependent events (Danio rerio)
phospho-PLA2 pathway (Danio rerio)
Phosphorylation of cPLA2 by ERK-2 (Danio rerio)
ADP [cytosol]
Signaling by Hedgehog (Danio rerio)
Hedgehog 'off' state (Danio rerio)
GLI3 is processed to GLI3R by the proteasome (Danio rerio)
CK1 phosphorylates p-GLI3 (Danio rerio)
ADP [cytosol]
PKA phosphorylates GLI3 (Danio rerio)
ADP [cytosol]
Hedgehog ligand biogenesis (Danio rerio)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Danio rerio)
ADP [cytosol]
Signaling by Hippo (Danio rerio)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Danio rerio)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Danio rerio)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Danio rerio)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Danio rerio)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Danio rerio)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Danio rerio)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Danio rerio)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Danio rerio)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Danio rerio)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Danio rerio)
Signaling by PTK6 (Danio rerio)
ERBB2 Activates PTK6 Signaling (Danio rerio)
ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
ADP [cytosol]
PTK6 Activates STAT3 (Danio rerio)
PTK6 phosphorylates STAP2 (Danio rerio)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Danio rerio)
PTK6 phosphorylates CDKN1B (Danio rerio)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Danio rerio)
PTK6 phosphorylates ARHGAP35 (Danio rerio)
ADP [cytosol]
PTK6 phosphorylates PXN (Danio rerio)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Danio rerio)
PTK6 phosphorylates AKT1 (Danio rerio)
ADP [cytosol]
PTK6 phosphorylates CBL (Danio rerio)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Danio rerio)
ADP [cytosol]
Signaling by Nuclear Receptors (Danio rerio)
ESR-mediated signaling (Danio rerio)
Extra-nuclear estrogen signaling (Danio rerio)
ESR-associated SRC autophosphorylates (Danio rerio)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by ALK (Danio rerio)
ALK autophosphorylation (Danio rerio)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Danio rerio)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Danio rerio)
ADP [cytosol]
Signaling by EGFR (Danio rerio)
EGFR autophosphorylation (Danio rerio)
ADP [cytosol]
EGFR downregulation (Danio rerio)
Phosphorylation of CBL (EGFR:CBL) (Danio rerio)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Danio rerio)
EGFR activates PLC-gamma1 by phosphorylation (Danio rerio)
ADP [cytosol]
GAB1 signalosome (Danio rerio)
GAB1 phosphorylation by EGFR kinase (Danio rerio)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Danio rerio)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Danio rerio)
ADP [cytosol]
Signaling by ERBB2 (Danio rerio)
ERBB2 Activates PTK6 Signaling (Danio rerio)
ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
ADP [cytosol]
PI3K events in ERBB2 signaling (Danio rerio)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Danio rerio)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Danio rerio)
SHC1 phosphorylation by ERBB2 heterodimers (Danio rerio)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Danio rerio)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Danio rerio)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Danio rerio)
ADP [cytosol]
Signaling by ERBB4 (Danio rerio)
PI3K events in ERBB4 signaling (Danio rerio)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Danio rerio)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Danio rerio)
ADP [cytosol]
Signaling by FGFR (Danio rerio)
Signaling by FGFR1 (Danio rerio)
Downstream signaling of activated FGFR1 (Danio rerio)
FRS-mediated FGFR1 signaling (Danio rerio)
Activated FGFR1 phosphorylates FRS2 (Danio rerio)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Danio rerio)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Danio rerio)
ADP [cytosol]
PI-3K cascade:FGFR1 (Danio rerio)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Danio rerio)
Activated FGFR1 phosphorylates PLCG1 (Danio rerio)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Danio rerio)
Activated FGFR1 phosphorylates SHC1 (Danio rerio)
ADP [cytosol]
FGFR1 ligand binding and activation (Danio rerio)
FGFR1b ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR1b (Danio rerio)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Danio rerio)
ADP [cytosol]
FGFR1c ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR1c (Danio rerio)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Danio rerio)
ADP [cytosol]
Spry regulation of FGF signaling (Danio rerio)
SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)
ADP [cytosol]
Signaling by FGFR2 (Danio rerio)
Downstream signaling of activated FGFR2 (Danio rerio)
FRS-mediated FGFR2 signaling (Danio rerio)
Activated FGFR2 phosphorylates FRS3 (Danio rerio)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Danio rerio)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Danio rerio)
Activated FGFR2 phosphorylates PLCG1 (Danio rerio)
ADP [cytosol]
FGFR2 ligand binding and activation (Danio rerio)
FGFR2b ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR2b (Danio rerio)
ADP [cytosol]
FGFR2c ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR2c (Danio rerio)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Danio rerio)
Spry regulation of FGF signaling (Danio rerio)
SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)
ADP [cytosol]
Signaling by FGFR3 (Danio rerio)
Downstream signaling of activated FGFR3 (Danio rerio)
FRS-mediated FGFR3 signaling (Danio rerio)
Activated FGFR3 phosphorylates FRS3 (Danio rerio)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Danio rerio)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Danio rerio)
Activated FGFR3 phosphorylates PLCG1 (Danio rerio)
ADP [cytosol]
FGFR3 ligand binding and activation (Danio rerio)
FGFR3b ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR3b (Danio rerio)
ADP [cytosol]
FGFR3c ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR3c (Danio rerio)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Danio rerio)
Spry regulation of FGF signaling (Danio rerio)
SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)
ADP [cytosol]
Signaling by FGFR4 (Danio rerio)
Downstream signaling of activated FGFR4 (Danio rerio)
FRS-mediated FGFR4 signaling (Danio rerio)
Activated FGFR4 phosphorylates FRS3 (Danio rerio)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Danio rerio)
Activated FGFR4 phosphorylates PLCG1 (Danio rerio)
ADP [cytosol]
FGFR4 ligand binding and activation (Danio rerio)
Autocatalytic phosphorylation of FGFR4 (Danio rerio)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Danio rerio)
Spry regulation of FGF signaling (Danio rerio)
SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)
ADP [cytosol]
Signaling by Insulin receptor (Danio rerio)
Autophosphorylation of insulin receptor (Danio rerio)
ADP [cytosol]
Insulin receptor signalling cascade (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
Activation of AKT2 (Danio rerio)
PDPK1 phosphorylates AKT2 (Danio rerio)
ADP [cytosol]
Signaling by LTK (Danio rerio)
Autophosphorylation of LTK dimer:ALKAL1,2 (Danio rerio)
ADP [cytosol]
Signaling by MET (Danio rerio)
Negative regulation of MET activity (Danio rerio)
MET phosphorylates CBL (Danio rerio)
ADP [cytosol]
Signaling by MST1 (Danio rerio)
MST1R autophosphorylates (Danio rerio)
ADP [cytosol]
Signaling by NTRKs (Danio rerio)
Signaling by NTRK1 (TRKA) (Danio rerio)
Signalling to ERKs (Danio rerio)
Prolonged ERK activation events (Danio rerio)
ARMS-mediated activation (Danio rerio)
ARMS is phosphorylated by active TrkA receptor (Danio rerio)
ADP [cytosol]
Frs2-mediated activation (Danio rerio)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Danio rerio)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Danio rerio)
ADP [cytosol]
Signalling to RAS (Danio rerio)
p38MAPK events (Danio rerio)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)
ADP [cytosol]
Signaling by PDGF (Danio rerio)
Autophosphorylation of PDGF alpha receptors (Danio rerio)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Danio rerio)
ADP [cytosol]
Downstream signal transduction (Danio rerio)
Activation of Src (Danio rerio)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Danio rerio)
ADP [cytosol]
Signaling by SCF-KIT (Danio rerio)
Autophosphorylation of KIT (Danio rerio)
ADP [cytosol]
Phosphorylation of JAK2 (Danio rerio)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Danio rerio)
ADP [cytosol]
Phosphorylation of STATs (Danio rerio)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Danio rerio)
ADP [cytosol]
Regulation of KIT signaling (Danio rerio)
Phosphorylation of APS (Danio rerio)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Danio rerio)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Danio rerio)
IGF1R signaling cascade (Danio rerio)
IRS-related events triggered by IGF1R (Danio rerio)
IRS-mediated signalling (Danio rerio)
PI3K Cascade (Danio rerio)
Activation of AKT2 (Danio rerio)
PDPK1 phosphorylates AKT2 (Danio rerio)
ADP [cytosol]
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
FYN autophosphorylates (Danio rerio)
ADP [cytosol]
FYN phosphorylates PAK2 (Danio rerio)
ADP [cytosol]
PAK2 autophorylates (Danio rerio)
ADP [cytosol]
Phosphorylation of SRC-1 (Danio rerio)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
ADP [cytosol]
VEGFR2 autophosphorylates (Danio rerio)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Danio rerio)
PDK1 phosphorylates PKC (Danio rerio)
ADP [cytosol]
PKC autophosphorylates (Danio rerio)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Danio rerio)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Danio rerio)
PAK1-3 phosphorylates VE-cadherin (Danio rerio)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Danio rerio)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Danio rerio)
ADP [cytosol]
p38 MAPK activation by VEGFR (Danio rerio)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate NADPH Oxidases (Danio rerio)
PKC phosphorylates NCF1 (Danio rerio)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Danio rerio)
Branching and elongation of mother and daughter filaments (Danio rerio)
Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
Actin:ADP [cytosol] (Danio rerio)
ADP [cytosol]
Detachment of WASP/WAVE (Danio rerio)
Mother filament:ARP2/3:actin:ADP [cytosol] (Danio rerio)
Actin:ADP [cytosol] (Danio rerio)
ADP [cytosol]
RHO GTPases activate PAKs (Danio rerio)
Autophosphorylation of PAK1,2,3 (Danio rerio)
ADP [cytosol]
RHO GTPases activate PKNs (Danio rerio)
PDPK1 phosphorylates PKN1,2,3 (Danio rerio)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Danio rerio)
ADP [cytosol]
Signaling by TGFB family members (Danio rerio)
Signaling by Activin (Danio rerio)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Danio rerio)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)
ADP [cytosol]
Signaling by BMP (Danio rerio)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Danio rerio)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Danio rerio)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Danio rerio)
TGF-beta receptor signaling activates SMADs (Danio rerio)
Activated type I receptor phosphorylates SMAD2/3 directly (Danio rerio)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Danio rerio)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Danio rerio)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Danio rerio)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Danio rerio)
ADP [cytosol]
Signaling by WNT (Danio rerio)
TCF dependent signaling in response to WNT (Danio rerio)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Danio rerio)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Danio rerio)
ADP [cytosol]
WNT mediated activation of DVL (Danio rerio)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Danio rerio)
ADP [cytosol]
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
ABC transporters in lipid homeostasis (Danio rerio)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Danio rerio)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Danio rerio)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Danio rerio)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Danio rerio)
ADP [cytosol]
HCO3- transport through ion channel (Danio rerio)
ADP [cytosol]
The ABCC family mediates organic anion transport (Danio rerio)
ADP [cytosol]
Aquaporin-mediated transport (Danio rerio)
Vasopressin regulates renal water homeostasis via Aquaporins (Danio rerio)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Danio rerio)
ADP [cytosol]
Ion channel transport (Danio rerio)
Ion transport by P-type ATPases (Danio rerio)
ATP13A2 transports cations from cytosol to lysosomal lumen (Danio rerio)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Danio rerio)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Danio rerio)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Danio rerio)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Danio rerio)
ADP [cytosol]
Iron uptake and transport (Danio rerio)
Transferrin endocytosis and recycling (Danio rerio)
Acidification of Tf:TfR1 containing endosome (Danio rerio)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Danio rerio)
Plasma lipoprotein assembly (Danio rerio)
HDL assembly (Danio rerio)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Danio rerio)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Danio rerio)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Danio rerio)
ADP [cytosol]
Plasma lipoprotein remodeling (Danio rerio)
HDL remodeling (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
ADP [cytosol]
SLC-mediated transmembrane transport (Danio rerio)
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Danio rerio)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Danio rerio)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Danio rerio)
ADP [cytosol]
Vesicle-mediated transport (Danio rerio)
Membrane Trafficking (Danio rerio)
ER to Golgi Anterograde Transport (Danio rerio)
COPI-mediated anterograde transport (Danio rerio)
GBF1 stimulates ARF nucleotide exchange (Danio rerio)
ADP [cytosol]
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
AMPK (complex) phosphorylates ULK1 (complex) (Dictyostelium discoideum)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Dictyostelium discoideum)
ADP [cytosol]
Selective autophagy (Dictyostelium discoideum)
Mitophagy (Dictyostelium discoideum)
Receptor Mediated Mitophagy (Dictyostelium discoideum)
FUNDC1 is phosphorylated by CK2 (Dictyostelium discoideum)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Dictyostelium discoideum)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Dictyostelium discoideum)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Dictyostelium discoideum)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
ADP [cytosol]
Cell Cycle (Dictyostelium discoideum)
Cell Cycle, Mitotic (Dictyostelium discoideum)
M Phase (Dictyostelium discoideum)
Mitotic Metaphase and Anaphase (Dictyostelium discoideum)
Mitotic Anaphase (Dictyostelium discoideum)
Nuclear Envelope (NE) Reassembly (Dictyostelium discoideum)
Sealing of the nuclear envelope (NE) by ESCRT-III (Dictyostelium discoideum)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)
ADP [cytosol]
Mitotic Prometaphase (Dictyostelium discoideum)
Condensation of Prometaphase Chromosomes (Dictyostelium discoideum)
CK2 phosphorylates condensin I subunits (Dictyostelium discoideum)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Dictyostelium discoideum)
PLK1 phosphorylates NUDC (Dictyostelium discoideum)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Dictyostelium discoideum)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Dictyostelium discoideum)
ADP [cytosol]
Mitotic Prophase (Dictyostelium discoideum)
Golgi Cisternae Pericentriolar Stack Reorganization (Dictyostelium discoideum)
PLK1 phosphorylates GORASP1 (Dictyostelium discoideum)
ADP [cytosol]
Mitotic G2-G2/M phases (Dictyostelium discoideum)
G2/M Transition (Dictyostelium discoideum)
Polo-like kinase mediated events (Dictyostelium discoideum)
Activation of Cdc25C (Dictyostelium discoideum)
ADP [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Cellular Senescence (Dictyostelium discoideum)
Oxidative Stress Induced Senescence (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Cellular response to heat stress (Dictyostelium discoideum)
Regulation of HSF1-mediated heat shock response (Dictyostelium discoideum)
Constitutive phosphorylation by pERK1/2 (Dictyostelium discoideum)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Dictyostelium discoideum)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Dictyostelium discoideum)
ADP [cytosol]
HSP70s:ADP [cytosol] (Dictyostelium discoideum)
HSP13:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP14:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA2:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA4:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA5:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA6:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA8:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA9:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Dictyostelium discoideum)
HSP70s:ADP [cytosol] (Dictyostelium discoideum)
HSP13:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP14:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA2:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA4:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA5:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA6:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA8:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSPA9:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Dictyostelium discoideum)
ATP binding to HSP90 triggers conformation change (Dictyostelium discoideum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Dictyostelium discoideum)
HSP70:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Dictyostelium discoideum)
HSP70:ADP:nascent protein [cytosol] (Dictyostelium discoideum)
HSP70:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
ATP hydrolysis by HSP70 (Dictyostelium discoideum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Dictyostelium discoideum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Dictyostelium discoideum)
HSP70:ADP:nascent protein [cytosol] (Dictyostelium discoideum)
HSP70:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Unfolded Protein Response (UPR) (Dictyostelium discoideum)
IRE1alpha activates chaperones (Dictyostelium discoideum)
IRE1 dimer autophosphorylates (Dictyostelium discoideum)
ADP [cytosol]
Developmental Biology (Dictyostelium discoideum)
MITF-M-regulated melanocyte development (Dictyostelium discoideum)
Transcriptional and post-translational regulation of MITF-M expression and activity (Dictyostelium discoideum)
MAPK-dependent phosphorylation of KARS (Dictyostelium discoideum)
ADP [cytosol]
Nervous system development (Dictyostelium discoideum)
Axon guidance (Dictyostelium discoideum)
EPH-Ephrin signaling (Dictyostelium discoideum)
EPHB-mediated forward signaling (Dictyostelium discoideum)
PAK1 autophosphorylates (Dictyostelium discoideum)
ADP [cytosol]
L1CAM interactions (Dictyostelium discoideum)
Recycling pathway of L1 (Dictyostelium discoideum)
Phosphorylation of L1 by ERK (Dictyostelium discoideum)
ADP [cytosol]
Signal transduction by L1 (Dictyostelium discoideum)
Interaction of PAK1 with Rac1-GTP (Dictyostelium discoideum)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Dictyostelium discoideum)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Dictyostelium discoideum)
ADP [cytosol]
Semaphorin interactions (Dictyostelium discoideum)
Sema3A PAK dependent Axon repulsion (Dictyostelium discoideum)
Transphosphorylation of pLIMK1 (Dictyostelium discoideum)
ADP [cytosol]
Drug ADME (Dictyostelium discoideum)
Aspirin ADME (Dictyostelium discoideum)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Dictyostelium discoideum)
ADP [cytosol]
Azathioprine ADME (Dictyostelium discoideum)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Dictyostelium discoideum)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Dictyostelium discoideum)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Dictyostelium discoideum)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Dictyostelium discoideum)
ADP [cytosol]
Ciprofloxacin ADME (Dictyostelium discoideum)
ABCG2 transports Cipro from hepatic cell to extracellular space (Dictyostelium discoideum)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Dictyostelium discoideum)
ADP [cytosol]
Paracetamol ADME (Dictyostelium discoideum)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)
ADP [cytosol]
Prednisone ADME (Dictyostelium discoideum)
ABCB1 transports PREDN,PREDL out of hepatic cells (Dictyostelium discoideum)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Dictyostelium discoideum)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Dictyostelium discoideum)
ADP [cytosol]
Ribavirin ADME (Dictyostelium discoideum)
ADK phosphorylates RBV (Dictyostelium discoideum)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Dictyostelium discoideum)
ADP [cytosol]
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
Regulation of TP53 Activity (Dictyostelium discoideum)
Regulation of TP53 Expression and Degradation (Dictyostelium discoideum)
Regulation of TP53 Degradation (Dictyostelium discoideum)
PDPK1 phosphorylates SGK1 (Dictyostelium discoideum)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Dictyostelium discoideum)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
AKT phosphorylates TSC2, inhibiting it (Dictyostelium discoideum)
ADP [cytosol]
Hemostasis (Dictyostelium discoideum)
Factors involved in megakaryocyte development and platelet production (Dictyostelium discoideum)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Dictyostelium discoideum)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Dictyostelium discoideum)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Dictyostelium discoideum)
ADP [cytosol]
Platelet activation, signaling and aggregation (Dictyostelium discoideum)
Effects of PIP2 hydrolysis (Dictyostelium discoideum)
DAG kinase produces phosphatidic acid from DAG (Dictyostelium discoideum)
ADP [cytosol]
GPVI-mediated activation cascade (Dictyostelium discoideum)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Dictyostelium discoideum)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Dictyostelium discoideum)
Disinhibition of SNARE formation (Dictyostelium discoideum)
Phosphorylation of Platelet Sec-1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Dictyostelium discoideum)
ADP [cytosol]
Platelet degranulation (Dictyostelium discoideum)
ABCC4 accumulation of dense granule contents (Dictyostelium discoideum)
ADP [cytosol]
Signal amplification (Dictyostelium discoideum)
ADP signalling through P2Y purinoceptor 1 (Dictyostelium discoideum)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)
ADP [cytosol]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Costimulation by the CD28 family (Dictyostelium discoideum)
CD28 co-stimulation (Dictyostelium discoideum)
CD28 dependent PI3K/Akt signaling (Dictyostelium discoideum)
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Dictyostelium discoideum)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Dictyostelium discoideum)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Dictyostelium discoideum)
ADP [cytosol]
TCR signaling (Dictyostelium discoideum)
Downstream TCR signaling (Dictyostelium discoideum)
Phosphorylation of PKC theta (Dictyostelium discoideum)
ADP [cytosol]
Cytokine Signaling in Immune system (Dictyostelium discoideum)
Signaling by Interleukins (Dictyostelium discoideum)
Interleukin-1 family signaling (Dictyostelium discoideum)
Interleukin-37 signaling (Dictyostelium discoideum)
STAT3 phosphorylation (Dictyostelium discoideum)
ADP [cytosol]
Interleukin-38 signaling (Dictyostelium discoideum)
MAPK8 phosphorylation (Dictyostelium discoideum)
ADP [cytosol]
Interleukin-17 signaling (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Innate Immune System (Dictyostelium discoideum)
Cytosolic sensors of pathogen-associated DNA (Dictyostelium discoideum)
STING mediated induction of host immune responses (Dictyostelium discoideum)
STAT6-mediated induction of chemokines (Dictyostelium discoideum)
p-S407-STAT6 is phosphorylated at Tyr641 (Dictyostelium discoideum)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Dictyostelium discoideum)
FCERI mediated MAPK activation (Dictyostelium discoideum)
Phosphorylation of MEK4 by MEKK1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
FCERI mediated NF-kB activation (Dictyostelium discoideum)
Autophosphorylation of PKC-theta (Dictyostelium discoideum)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Dictyostelium discoideum)
Regulation of actin dynamics for phagocytic cup formation (Dictyostelium discoideum)
Autophosphorylation of PAK1 (Dictyostelium discoideum)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Dictyostelium discoideum)
Mother filament:ARP2/3:actin:ADP [cytosol] (Dictyostelium discoideum)
Actin:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Detachment of WASP/WAVE (Dictyostelium discoideum)
Mother filament:ARP2/3:actin:ADP [cytosol] (Dictyostelium discoideum)
Actin:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Dictyostelium discoideum)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Dictyostelium discoideum)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Dictyostelium discoideum)
ADP [cytosol]
Role of phospholipids in phagocytosis (Dictyostelium discoideum)
DAG stimulates protein kinase C-delta (Dictyostelium discoideum)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Dictyostelium discoideum)
NOD1/2 Signaling Pathway (Dictyostelium discoideum)
Activation of p38 MAPK (Dictyostelium discoideum)
ADP [cytosol]
Toll-like Receptor Cascades (Dictyostelium discoideum)
Toll Like Receptor 10 (TLR10) Cascade (Dictyostelium discoideum)
MyD88 cascade initiated on plasma membrane (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Dictyostelium discoideum)
Toll Like Receptor TLR1:TLR2 Cascade (Dictyostelium discoideum)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Dictyostelium discoideum)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Dictyostelium discoideum)
MyD88-independent TLR4 cascade (Dictyostelium discoideum)
TRIF (TICAM1)-mediated TLR4 signaling (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Dictyostelium discoideum)
MyD88 cascade initiated on plasma membrane (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Dictyostelium discoideum)
MyD88 dependent cascade initiated on endosome (Dictyostelium discoideum)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Dictyostelium discoideum)
MyD88 dependent cascade initiated on endosome (Dictyostelium discoideum)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Dictyostelium discoideum)
MAP kinase activation (Dictyostelium discoideum)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
ADP [cytosol]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Pyruvate metabolism (Dictyostelium discoideum)
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
ADP [cytosol]
Biological oxidations (Dictyostelium discoideum)
Phase II - Conjugation of compounds (Dictyostelium discoideum)
Glutathione conjugation (Dictyostelium discoideum)
Glutathione synthesis and recycling (Dictyostelium discoideum)
GSS:Mg2+ dimer synthesizes GSH (Dictyostelium discoideum)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)
ADP [cytosol]
Inositol phosphate metabolism (Dictyostelium discoideum)
Synthesis of IP3 and IP4 in the cytosol (Dictyostelium discoideum)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Dictyostelium discoideum)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of carbohydrates (Dictyostelium discoideum)
Fructose metabolism (Dictyostelium discoideum)
Fructose catabolism (Dictyostelium discoideum)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Dictyostelium discoideum)
ADP [cytosol]
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Dictyostelium discoideum)
ADP [cytosol]
Glycolysis (Dictyostelium discoideum)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Dictyostelium discoideum)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Dictyostelium discoideum)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Dictyostelium discoideum)
ADP [cytosol]
Pentose phosphate pathway (Dictyostelium discoideum)
RBKS phosphorylates ribose to R5P (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Carnitine metabolism (Dictyostelium discoideum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Dictyostelium discoideum)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of steroids (Dictyostelium discoideum)
Bile acid and bile salt metabolism (Dictyostelium discoideum)
Recycling of bile acids and salts (Dictyostelium discoideum)
ABCB11 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of bile acids and bile salts (Dictyostelium discoideum)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Dictyostelium discoideum)
ABCB11 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
Cholesterol biosynthesis (Dictyostelium discoideum)
MVD decarboxylates MVA5PP to IPPP (Dictyostelium discoideum)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Dictyostelium discoideum)
ADP [cytosol]
Phospholipid metabolism (Dictyostelium discoideum)
Glycerophospholipid biosynthesis (Dictyostelium discoideum)
Synthesis of PE (Dictyostelium discoideum)
ETA is phosphorylated to PETA by CHK/ETNK (Dictyostelium discoideum)
ADP [cytosol]
PI Metabolism (Dictyostelium discoideum)
Synthesis of PIPs at the ER membrane (Dictyostelium discoideum)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Dictyostelium discoideum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Dictyostelium discoideum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Dictyostelium discoideum)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Dictyostelium discoideum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Dictyostelium discoideum)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
Sphingolipid metabolism (Dictyostelium discoideum)
Sphingolipid de novo biosynthesis (Dictyostelium discoideum)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Dictyostelium discoideum)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Dictyostelium discoideum)
ADP [cytosol]
Triglyceride metabolism (Dictyostelium discoideum)
Triglyceride biosynthesis (Dictyostelium discoideum)
Conversion of Glycerol to Glycerol-3-phosphate (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Dictyostelium discoideum)
eNOS activation (Dictyostelium discoideum)
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Dictyostelium discoideum)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Dictyostelium discoideum)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Dictyostelium discoideum)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Dictyostelium discoideum)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Dictyostelium discoideum)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Dictyostelium discoideum)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Dictyostelium discoideum)
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Dictyostelium discoideum)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Dictyostelium discoideum)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Dictyostelium discoideum)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Dictyostelium discoideum)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Dictyostelium discoideum)
ADP [cytosol]
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Dictyostelium discoideum)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Dictyostelium discoideum)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Dictyostelium discoideum)
ADP [cytosol]
Pyrimidine biosynthesis (Dictyostelium discoideum)
CAD hexamer transforms L-Gln to CAP (Dictyostelium discoideum)
ADP [cytosol]
Nucleotide salvage (Dictyostelium discoideum)
Purine salvage (Dictyostelium discoideum)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Dictyostelium discoideum)
ADP [cytosol]
Pyrimidine salvage (Dictyostelium discoideum)
UCKL1 phosphorylates urindine, cytidine (Dictyostelium discoideum)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Dictyostelium discoideum)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Dictyostelium discoideum)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of porphyrins (Dictyostelium discoideum)
Heme biosynthesis (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
Heme degradation (Dictyostelium discoideum)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Transport of RCbl within the body (Dictyostelium discoideum)
ABCC1 transports cytosolic RCbl to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Dictyostelium discoideum)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Dictyostelium discoideum)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of folate and pterines (Dictyostelium discoideum)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Dictyostelium discoideum)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Dictyostelium discoideum)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Dictyostelium discoideum)
ADP [cytosol]
Nicotinate metabolism (Dictyostelium discoideum)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Dictyostelium discoideum)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Dictyostelium discoideum)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Dictyostelium discoideum)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Dictyostelium discoideum)
Coenzyme A biosynthesis (Dictyostelium discoideum)
COASY phosphorylates DP-CoA (Dictyostelium discoideum)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Dictyostelium discoideum)
2xPDKX:2xZn2+ phosphorylates PDX (Dictyostelium discoideum)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Dictyostelium discoideum)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of RNA (Dictyostelium discoideum)
Nonsense-Mediated Decay (NMD) (Dictyostelium discoideum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Dictyostelium discoideum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Dictyostelium discoideum)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Dictyostelium discoideum)
Protein Kinase B/Akt phosphorylates BRF1 (Dictyostelium discoideum)
ADP [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
Synthesis of substrates in N-glycan biosythesis (Dictyostelium discoideum)
GDP-fucose biosynthesis (Dictyostelium discoideum)
FUK phosphorylates beta-Fuc to Fuc1P (Dictyostelium discoideum)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Dictyostelium discoideum)
MVD decarboxylates MVA5PP to IPPP (Dictyostelium discoideum)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Dictyostelium discoideum)
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPI-mediated anterograde transport (Dictyostelium discoideum)
GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)
ADP [cytosol]
COPII-mediated vesicle transport (Dictyostelium discoideum)
CSNK1D phosphorylates SEC23 (Dictyostelium discoideum)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Dictyostelium discoideum)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Dictyostelium discoideum)
ADP [cytosol]
Protein folding (Dictyostelium discoideum)
Chaperonin-mediated protein folding (Dictyostelium discoideum)
Association of TriC/CCT with target proteins during biosynthesis (Dictyostelium discoideum)
Association of CCT/TriC with sphingosine kinase 1 (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Dictyostelium discoideum)
ATP binds G-protein beta associated TRiC/CCT (Dictyostelium discoideum)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Dictyostelium discoideum)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Surfactant metabolism (Dictyostelium discoideum)
ABCA3 transports PC, PG from ER membrane to lamellar body (Dictyostelium discoideum)
ADP [cytosol]
Translation (Dictyostelium discoideum)
Eukaryotic Translation Initiation (Dictyostelium discoideum)
Cap-dependent Translation Initiation (Dictyostelium discoideum)
Ribosomal scanning and start codon recognition (Dictyostelium discoideum)
Ribosomal scanning (Dictyostelium discoideum)
ADP [cytosol]
Sensory Perception (Dictyostelium discoideum)
Visual phototransduction (Dictyostelium discoideum)
The canonical retinoid cycle in rods (twilight vision) (Dictyostelium discoideum)
ABCA4 mediates atRAL transport (Dictyostelium discoideum)
ADP [cytosol]
Signal Transduction (Dictyostelium discoideum)
Death Receptor Signaling (Dictyostelium discoideum)
p75 NTR receptor-mediated signalling (Dictyostelium discoideum)
Cell death signalling via NRAGE, NRIF and NADE (Dictyostelium discoideum)
NRAGE signals death through JNK (Dictyostelium discoideum)
GTP-bound RAC contributes to JNK activation (Dictyostelium discoideum)
ADP [cytosol]
Intracellular signaling by second messengers (Dictyostelium discoideum)
DAG and IP3 signaling (Dictyostelium discoideum)
DAG stimulates protein kinase C-delta (Dictyostelium discoideum)
ADP [cytosol]
PIP3 activates AKT signaling (Dictyostelium discoideum)
AKT phosphorylates targets in the cytosol (Dictyostelium discoideum)
AKT phosphorylates MKRN1 (Dictyostelium discoideum)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Dictyostelium discoideum)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Dictyostelium discoideum)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Dictyostelium discoideum)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Dictyostelium discoideum)
ADP [cytosol]
PTEN Regulation (Dictyostelium discoideum)
Regulation of PTEN gene transcription (Dictyostelium discoideum)
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
ADP [cytosol]
Regulation of PTEN stability and activity (Dictyostelium discoideum)
AKT phosphorylates MKRN1 (Dictyostelium discoideum)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Dictyostelium discoideum)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Dictyostelium discoideum)
ADP [cytosol]
MAPK family signaling cascades (Dictyostelium discoideum)
MAPK1/MAPK3 signaling (Dictyostelium discoideum)
RAF-independent MAPK1/3 activation (Dictyostelium discoideum)
MAPK1 (ERK2) activation (Dictyostelium discoideum)
MAP2K2 phosphorylates MAPK1 (Dictyostelium discoideum)
ADP [cytosol]
MAPK3 (ERK1) activation (Dictyostelium discoideum)
MAP2K1 phosphorylates MAPK3 (Dictyostelium discoideum)
ADP [cytosol]
RAF/MAP kinase cascade (Dictyostelium discoideum)
MAP2K and MAPK activation (Dictyostelium discoideum)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Dictyostelium discoideum)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
Negative regulation of MAPK pathway (Dictyostelium discoideum)
Negative feedback regulation of MAPK pathway (Dictyostelium discoideum)
Activated MAPKs phosphorylate MAP2K1 (Dictyostelium discoideum)
ADP [cytosol]
RAF activation (Dictyostelium discoideum)
MARK3 phosphorylates KSR1 (Dictyostelium discoideum)
ADP [cytosol]
MAPK6/MAPK4 signaling (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Dictyostelium discoideum)
ADP [cytosol]
MTOR signalling (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Dictyostelium discoideum)
Phosphorylation of TSC2 by PKB (Dictyostelium discoideum)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
ADP [cytosol]
mTORC1-mediated signalling (Dictyostelium discoideum)
Phosphorylation and activation of eIF4G by activated S6K1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Dictyostelium discoideum)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
ADP [cytosol]
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (q) signalling events (Dictyostelium discoideum)
Effects of PIP2 hydrolysis (Dictyostelium discoideum)
DAG kinase produces phosphatidic acid from DAG (Dictyostelium discoideum)
ADP [cytosol]
G-protein beta:gamma signalling (Dictyostelium discoideum)
G beta:gamma signalling through PI3Kgamma (Dictyostelium discoideum)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
Estrogen-stimulated signaling through PRKCZ (Dictyostelium discoideum)
PRKCZ autophosphorylates downstream of estrogen stimulation (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by ERBB2 (Dictyostelium discoideum)
Downregulation of ERBB2 signaling (Dictyostelium discoideum)
Downregulation of ERBB2:ERBB3 signaling (Dictyostelium discoideum)
Phosphorylation of USP8 by P-AKT (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Insulin receptor (Dictyostelium discoideum)
Insulin receptor signalling cascade (Dictyostelium discoideum)
IRS-mediated signalling (Dictyostelium discoideum)
PI3K Cascade (Dictyostelium discoideum)
Activation of AKT2 (Dictyostelium discoideum)
PDPK1 phosphorylates AKT2 (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Dictyostelium discoideum)
IGF1R signaling cascade (Dictyostelium discoideum)
IRS-related events triggered by IGF1R (Dictyostelium discoideum)
IRS-mediated signalling (Dictyostelium discoideum)
PI3K Cascade (Dictyostelium discoideum)
Activation of AKT2 (Dictyostelium discoideum)
PDPK1 phosphorylates AKT2 (Dictyostelium discoideum)
ADP [cytosol]
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated cell proliferation (Dictyostelium discoideum)
PDK1 phosphorylates PKC (Dictyostelium discoideum)
ADP [cytosol]
PKC autophosphorylates (Dictyostelium discoideum)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Dictyostelium discoideum)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Dictyostelium discoideum)
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Dictyostelium discoideum)
RHOBTB3 ATPase cycle (Dictyostelium discoideum)
RHOBTB3 hydrolyzes ATP (Dictyostelium discoideum)
RHOBTB3:ADP [trans-Golgi network membrane] (Dictyostelium discoideum)
ADP [cytosol]
Signaling by Rho GTPases (Dictyostelium discoideum)
RHO GTPase Effectors (Dictyostelium discoideum)
RHO GTPases Activate NADPH Oxidases (Dictyostelium discoideum)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Dictyostelium discoideum)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Dictyostelium discoideum)
Branching and elongation of mother and daughter filaments (Dictyostelium discoideum)
Mother filament:ARP2/3:actin:ADP [cytosol] (Dictyostelium discoideum)
Actin:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
Detachment of WASP/WAVE (Dictyostelium discoideum)
Mother filament:ARP2/3:actin:ADP [cytosol] (Dictyostelium discoideum)
Actin:ADP [cytosol] (Dictyostelium discoideum)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Dictyostelium discoideum)
ADP [cytosol]
RHO GTPases activate PAKs (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
ADP [cytosol]
PAK1 phosphorylates FLNA (Dictyostelium discoideum)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Dictyostelium discoideum)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Dictyostelium discoideum)
ADP [cytosol]
RHO GTPases activate PKNs (Dictyostelium discoideum)
p-T774-PKN1 phosphorylates CDC25C (Dictyostelium discoideum)
ADP [cytosol]
Transport of small molecules (Dictyostelium discoideum)
ABC-family proteins mediated transport (Dictyostelium discoideum)
ABC transporters in lipid homeostasis (Dictyostelium discoideum)
ABCA12 transports lipids from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Dictyostelium discoideum)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Dictyostelium discoideum)
ADP [cytosol]
ABCAs mediate lipid efflux (Dictyostelium discoideum)
ADP [cytosol]
ABCAs mediate lipid influx (Dictyostelium discoideum)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Dictyostelium discoideum)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Dictyostelium discoideum)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCA4 mediates atRAL transport (Dictyostelium discoideum)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
HCO3- transport through ion channel (Dictyostelium discoideum)
ADP [cytosol]
The ABCC family mediates organic anion transport (Dictyostelium discoideum)
ADP [cytosol]
Ion channel transport (Dictyostelium discoideum)
Ion transport by P-type ATPases (Dictyostelium discoideum)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Dictyostelium discoideum)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Dictyostelium discoideum)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Dictyostelium discoideum)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Dictyostelium discoideum)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Dictyostelium discoideum)
ADP [cytosol]
Iron uptake and transport (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
ADP [cytosol]
Transferrin endocytosis and recycling (Dictyostelium discoideum)
Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Dictyostelium discoideum)
Plasma lipoprotein remodeling (Dictyostelium discoideum)
HDL remodeling (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
ADP [cytosol]
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Dictyostelium discoideum)
ADP [cytosol]
Vesicle-mediated transport (Dictyostelium discoideum)
Membrane Trafficking (Dictyostelium discoideum)
Clathrin-mediated endocytosis (Dictyostelium discoideum)
AAK1 phosphorylates AP-2 mu subunit at T156 (Dictyostelium discoideum)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Dictyostelium discoideum)
ADP [cytosol]
ER to Golgi Anterograde Transport (Dictyostelium discoideum)
COPI-mediated anterograde transport (Dictyostelium discoideum)
GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)
ADP [cytosol]
COPII-mediated vesicle transport (Dictyostelium discoideum)
CSNK1D phosphorylates SEC23 (Dictyostelium discoideum)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Dictyostelium discoideum)
ESCRT Disassembly (Dictyostelium discoideum)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Dictyostelium discoideum)
Intra-Golgi traffic (Dictyostelium discoideum)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Dictyostelium discoideum)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Dictyostelium discoideum)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Dictyostelium discoideum)
ADP [cytosol]
Rab regulation of trafficking (Dictyostelium discoideum)
RAB GEFs exchange GTP for GDP on RABs (Dictyostelium discoideum)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Dictyostelium discoideum)
ADP [cytosol]
p-ULK1 phosphorylates DENND3 (Dictyostelium discoideum)
ADP [cytosol]
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
AMPK (complex) phosphorylates ULK1 (complex) (Drosophila melanogaster)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Drosophila melanogaster)
ADP [cytosol]
Selective autophagy (Drosophila melanogaster)
Mitophagy (Drosophila melanogaster)
Receptor Mediated Mitophagy (Drosophila melanogaster)
FUNDC1 is phosphorylated by CK2 (Drosophila melanogaster)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Drosophila melanogaster)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Drosophila melanogaster)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Drosophila melanogaster)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Drosophila melanogaster)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
ADP [cytosol]
Cell Cycle (Drosophila melanogaster)
Cell Cycle Checkpoints (Drosophila melanogaster)
G2/M Checkpoints (Drosophila melanogaster)
G2/M DNA replication checkpoint (Drosophila melanogaster)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)
ADP [cytosol]
Cell Cycle, Mitotic (Drosophila melanogaster)
M Phase (Drosophila melanogaster)
Mitotic Prometaphase (Drosophila melanogaster)
Condensation of Prometaphase Chromosomes (Drosophila melanogaster)
CK2 phosphorylates condensin I subunits (Drosophila melanogaster)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Drosophila melanogaster)
PLK1 phosphorylates NUDC (Drosophila melanogaster)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Drosophila melanogaster)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Drosophila melanogaster)
ADP [cytosol]
Mitotic Prophase (Drosophila melanogaster)
Golgi Cisternae Pericentriolar Stack Reorganization (Drosophila melanogaster)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Drosophila melanogaster)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Drosophila melanogaster)
ADP [cytosol]
Nuclear Envelope Breakdown (Drosophila melanogaster)
Nuclear Pore Complex (NPC) Disassembly (Drosophila melanogaster)
CDK1 phosphorylates NUP98 (Drosophila melanogaster)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Drosophila melanogaster)
G1 Phase (Drosophila melanogaster)
Cyclin D associated events in G1 (Drosophila melanogaster)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Drosophila melanogaster)
ADP [cytosol]
G1/S Transition (Drosophila melanogaster)
Cyclin E associated events during G1/S transition (Drosophila melanogaster)
AKT phosphorylates p21Cip1 and p27Kip1 (Drosophila melanogaster)
ADP [cytosol]
Mitotic G2-G2/M phases (Drosophila melanogaster)
G2/M Transition (Drosophila melanogaster)
Cyclin A/B1/B2 associated events during G2/M transition (Drosophila melanogaster)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Drosophila melanogaster)
ADP [cytosol]
Polo-like kinase mediated events (Drosophila melanogaster)
Activation of Cdc25C (Drosophila melanogaster)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Drosophila melanogaster)
CDK1 phosphorylates BORA (Drosophila melanogaster)
ADP [cytosol]
PLK1 phosphorylates BORA (Drosophila melanogaster)
ADP [cytosol]
PLK1 phosphorylates OPTN (Drosophila melanogaster)
ADP [cytosol]
S Phase (Drosophila melanogaster)
Cyclin A:Cdk2-associated events at S phase entry (Drosophila melanogaster)
AKT phosphorylates p21Cip1 and p27Kip1 (Drosophila melanogaster)
ADP [cytosol]
Cell-Cell communication (Drosophila melanogaster)
Nephrin family interactions (Drosophila melanogaster)
Phosphorylation of nephrin by FYN (Drosophila melanogaster)
ADP [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular Senescence (Drosophila melanogaster)
Oxidative Stress Induced Senescence (Drosophila melanogaster)
MAP3K5 phosphorylates MKK3 and MKK6 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Cellular response to chemical stress (Drosophila melanogaster)
KEAP1-NFE2L2 pathway (Drosophila melanogaster)
Nuclear events mediated by NFE2L2 (Drosophila melanogaster)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Drosophila melanogaster)
SRXN1 reduces hyperoxidized PRDX1 dimer (Drosophila melanogaster)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Drosophila melanogaster)
ADP [cytosol]
Cellular response to heat stress (Drosophila melanogaster)
Regulation of HSF1-mediated heat shock response (Drosophila melanogaster)
Constitutive phosphorylation by pERK1/2 (Drosophila melanogaster)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Drosophila melanogaster)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Drosophila melanogaster)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Drosophila melanogaster)
ATP binding to HSP90 triggers conformation change (Drosophila melanogaster)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
ATP hydrolysis by HSP70 (Drosophila melanogaster)
HSP40:HSP70:ADP:nascent protein [cytosol] (Drosophila melanogaster)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Drosophila melanogaster)
HSP40:HSP70:ADP:nascent protein [cytosol] (Drosophila melanogaster)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Drosophila melanogaster)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Unfolded Protein Response (UPR) (Drosophila melanogaster)
IRE1alpha activates chaperones (Drosophila melanogaster)
IRE1 dimer autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
PERK regulates gene expression (Drosophila melanogaster)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Drosophila melanogaster)
ADP [cytosol]
DNA Replication (Drosophila melanogaster)
DNA Replication Pre-Initiation (Drosophila melanogaster)
Assembly of the pre-replicative complex (Drosophila melanogaster)
Assembly of the ORC complex at the origin of replication (Drosophila melanogaster)
ORC6 is phosphorylated on T195 (Drosophila melanogaster)
ADP [cytosol]
Developmental Biology (Drosophila melanogaster)
MITF-M-regulated melanocyte development (Drosophila melanogaster)
Transcriptional and post-translational regulation of MITF-M expression and activity (Drosophila melanogaster)
MAPK-dependent phosphorylation of KARS (Drosophila melanogaster)
ADP [cytosol]
Nervous system development (Drosophila melanogaster)
Axon guidance (Drosophila melanogaster)
EPH-Ephrin signaling (Drosophila melanogaster)
EPH receptors autophosphorylate (Drosophila melanogaster)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Drosophila melanogaster)
SFKs phosphorylate VAV2,3 (Drosophila melanogaster)
ADP [cytosol]
EPHB-mediated forward signaling (Drosophila melanogaster)
EPHB phosphorylates TIAM1 (Drosophila melanogaster)
ADP [cytosol]
PAK1 autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Drosophila melanogaster)
ADP [cytosol]
Ephrin signaling (Drosophila melanogaster)
PAKs autophosphorylate (Drosophila melanogaster)
ADP [cytosol]
PAKs phosphorylate MLC (Drosophila melanogaster)
ADP [cytosol]
L1CAM interactions (Drosophila melanogaster)
Recycling pathway of L1 (Drosophila melanogaster)
Phosphorylation of L1 by ERK (Drosophila melanogaster)
ADP [cytosol]
Signal transduction by L1 (Drosophila melanogaster)
Interaction of PAK1 with Rac1-GTP (Drosophila melanogaster)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)
ADP [cytosol]
Netrin-1 signaling (Drosophila melanogaster)
DCC mediated attractive signaling (Drosophila melanogaster)
Phosphorylation of DCC by Fyn (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Drosophila melanogaster)
ADP [cytosol]
RET signaling (Drosophila melanogaster)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Drosophila melanogaster)
ADP [cytosol]
Semaphorin interactions (Drosophila melanogaster)
CRMPs in Sema3A signaling (Drosophila melanogaster)
Phosphorylation of CRMPs by Cdk5 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Drosophila melanogaster)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Drosophila melanogaster)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Drosophila melanogaster)
ADP [cytosol]
Sema4D in semaphorin signaling (Drosophila melanogaster)
Sema4D induced cell migration and growth-cone collapse (Drosophila melanogaster)
SEMA4D interacts with Plexin-B1:ErbB2 (Drosophila melanogaster)
ADP [cytosol]
Signaling by ROBO receptors (Drosophila melanogaster)
Role of ABL in ROBO-SLIT signaling (Drosophila melanogaster)
Phosphorylation of ROBO1 by ABL kinase (Drosophila melanogaster)
ADP [cytosol]
Drosophila signaling pathways (Drosophila melanogaster)
Circadian Clock pathway (Drosophila melanogaster)
Phosphorylation of PER and TIM (Drosophila melanogaster)
CRY is phosphorylated by SGG (Drosophila melanogaster)
ADP [cytosol]
PER is phosphorylated by DCO (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated PER is phosphorylated by CK2 (Drosophila melanogaster)
ADP [cytosol]
TIM is phosphorylated by CK2 (Drosophila melanogaster)
ADP [cytosol]
Hedgehog pathway (Drosophila melanogaster)
N-HH ligand bound to PTC receptor complex (Drosophila melanogaster)
Activation of CI (Drosophila melanogaster)
Liberation of CI from SU(FU) repression (Drosophila melanogaster)
ADP [cytosol]
Activation of SMO (Drosophila melanogaster)
Autophosphorylated FU phosphorylates COS (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of SMO (Drosophila melanogaster)
Phosphorylation of SMO by CKIalpha (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of SMO by PKA-C1 (Drosophila melanogaster)
ADP [cytosol]
N-HH ligand not bound to PTC receptor complex (Drosophila melanogaster)
Assembly of the CI containing complexes (Drosophila melanogaster)
Phosphorylation of CI (Drosophila melanogaster)
Further phosphorylation of CI by CKIalphaepsilon (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CI by PKA-C1 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CI by SGG (Drosophila melanogaster)
ADP [cytosol]
Hippo/Warts pathway (Drosophila melanogaster)
DS ligand bound to FT receptor (Drosophila melanogaster)
Formation of the Hippo kinase cassette (Drosophila melanogaster)
HPO dimer autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated HPO dimer phosphorylates SAV (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated HPO dimer phosphorylates WTS (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated WTS autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated HPO dimer phosphorylates TH (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation-dependent inhibition of YKI (Drosophila melanogaster)
YKI is phosphorylated by and then dissociates from phosphorylated WTS (Drosophila melanogaster)
ADP [cytosol]
Subcellular localisation of D (Drosophila melanogaster)
FT is phosphorylated by DCO (Drosophila melanogaster)
ADP [cytosol]
Imd pathway (Drosophila melanogaster)
Activation of the IkappaB kinase complex, KEY:IRD5 dimer:KEY (Drosophila melanogaster)
Activated TAK1 kinase is autophosphorylated (Drosophila melanogaster)
ADP [cytosol]
Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 (Drosophila melanogaster)
ADP [cytosol]
HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex (Drosophila melanogaster)
ADP [cytosol]
Catalytic processing of the nuclear factor, REL (Drosophila melanogaster)
Activated IkappaB kinase (IKK) complex, Phospho IRD5:KEY dimer, phosphorylates REL in the PGN:PGRP-LC/LE receptor 'signalling complex' (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
Formation of the cytosolic BSK 'scaffolding complex' (Drosophila melanogaster)
BSK is phosphorylated and activated by phosphorylated HEP kinase (Drosophila melanogaster)
ADP [cytosol]
CKA is phosphorylated by phosphorylated BSK kinase (Drosophila melanogaster)
ADP [cytosol]
Insulin receptor mediated signaling (Drosophila melanogaster)
Insulin signaling pathway (Drosophila melanogaster)
Activation of DAkt1 by DPDK1 (Drosophila melanogaster)
ADP [cytosol]
Autophosphorylation of DINR (Drosophila melanogaster)
ADP [cytosol]
Chico is phosphorylated (Drosophila melanogaster)
ADP [cytosol]
DAkt1-mediated phosphorylation inactivates DFOXO (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by Dp110 (Drosophila melanogaster)
ADP [cytosol]
TOR signaling pathway (Drosophila melanogaster)
Activated DAkt1 phosphorylates TSC2 which inhibits the TSC1/2 complex (Drosophila melanogaster)
ADP [cytosol]
Activated DTOR also phosphorylates D4EBP (Drosophila melanogaster)
ADP [cytosol]
Activated DTOR phosphorylates DS6K (Drosophila melanogaster)
ADP [cytosol]
DPDK1 phosphorylates and activates DS6K (Drosophila melanogaster)
ADP [cytosol]
DTOR is positively regulated by DRheb-GTP (Drosophila melanogaster)
ADP [cytosol]
JAK/STAT pathway (Drosophila melanogaster)
Formation of the activated STAT92E dimer and transport to the nucleus (Drosophila melanogaster)
STAT92E is phosphorylated by phosphorylated HOP (Drosophila melanogaster)
ADP [cytosol]
Formation of the activated receptor complex (Drosophila melanogaster)
Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)
ADP [cytosol]
Phosphorylated HOP phosphorylates DOME (Drosophila melanogaster)
ADP [cytosol]
Planar Cell Polarity pathway (Drosophila melanogaster)
Activation of Downstream Effectors (Drosophila melanogaster)
Activation of RAC1:GTP by FZ:DSH complex (Drosophila melanogaster)
RAC1:GTP and MSN activate HEP (Drosophila melanogaster)
ADP [cytosol]
JNK signalling (Drosophila melanogaster)
Formation of the cytosolic BSK 'scaffolding complex' (Drosophila melanogaster)
BSK is phosphorylated and activated by phosphorylated HEP kinase (Drosophila melanogaster)
ADP [cytosol]
CKA is phosphorylated by phosphorylated BSK kinase (Drosophila melanogaster)
ADP [cytosol]
RHO1 signalling (Drosophila melanogaster)
Activation of non-muscle Myosin II (Drosophila melanogaster)
ROK phosphorylates MBS (Drosophila melanogaster)
ADP [cytosol]
ROK phosphorylates SQH (Drosophila melanogaster)
ADP [cytosol]
Toll pathway (Drosophila melanogaster)
Degradation of NF-kappa-B inhibitor, CACT (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
DL and DIF homodimers complexed with CACT are all phosphorylated in the TL receptor 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
ADP [cytosol]
Wingless pathway (Drosophila melanogaster)
WG ligand bound to FZ receptors (Drosophila melanogaster)
Assembly of receptor complex (Drosophila melanogaster)
Phosphorylation of ARR (Drosophila melanogaster)
GISH further phosphorylates ARR in the receptor complex (Drosophila melanogaster)
ADP [cytosol]
Membrane localised SGG phosphorylates ARR (Drosophila melanogaster)
ADP [cytosol]
WG ligand not bound to FZ receptors (Drosophila melanogaster)
Assembly of the 'destruction complex' (Drosophila melanogaster)
Phosphorylation of ARM (Drosophila melanogaster)
Further phosphorylation of ARM by SGG (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of ARM by CKIalpha (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of AXN and APC (Drosophila melanogaster)
Further phosphorylation of APC by DCO (Drosophila melanogaster)
ADP [cytosol]
Further phosphorylation of APC by SGG (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of AXN and APC by DCO (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of AXN and APC by SGG (Drosophila melanogaster)
ADP [cytosol]
Drug ADME (Drosophila melanogaster)
Aspirin ADME (Drosophila melanogaster)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Drosophila melanogaster)
ADP [cytosol]
Azathioprine ADME (Drosophila melanogaster)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Drosophila melanogaster)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Drosophila melanogaster)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Drosophila melanogaster)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Drosophila melanogaster)
ADP [cytosol]
Ciprofloxacin ADME (Drosophila melanogaster)
ABCG2 transports Cipro from hepatic cell to extracellular space (Drosophila melanogaster)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Drosophila melanogaster)
ADP [cytosol]
Paracetamol ADME (Drosophila melanogaster)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Drosophila melanogaster)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Drosophila melanogaster)
ADP [cytosol]
Ribavirin ADME (Drosophila melanogaster)
ADK phosphorylates RBV (Drosophila melanogaster)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Drosophila melanogaster)
ADP [cytosol]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Drosophila melanogaster)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Drosophila melanogaster)
Regulation of RUNX3 expression and activity (Drosophila melanogaster)
SRC phosphorylates RUNX3 (Drosophila melanogaster)
ADP [cytosol]
Hemostasis (Drosophila melanogaster)
Factors involved in megakaryocyte development and platelet production (Drosophila melanogaster)
Kinesins (Drosophila melanogaster)
Kinesins move along microtubules consuming ATP (Drosophila melanogaster)
ADP [cytosol]
Platelet activation, signaling and aggregation (Drosophila melanogaster)
Effects of PIP2 hydrolysis (Drosophila melanogaster)
DAG kinase produces phosphatidic acid from DAG (Drosophila melanogaster)
ADP [cytosol]
GPVI-mediated activation cascade (Drosophila melanogaster)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Drosophila melanogaster)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Drosophila melanogaster)
Integrin signaling (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
ADP [cytosol]
SYK activation by SRC (Drosophila melanogaster)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Drosophila melanogaster)
Disinhibition of SNARE formation (Drosophila melanogaster)
Phosphorylation of Platelet Sec-1 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Drosophila melanogaster)
ADP [cytosol]
Platelet degranulation (Drosophila melanogaster)
ABCC4 accumulation of dense granule contents (Drosophila melanogaster)
ADP [cytosol]
Signal amplification (Drosophila melanogaster)
ADP signalling through P2Y purinoceptor 1 (Drosophila melanogaster)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Drosophila melanogaster)
ADP [cytosol]
Platelet homeostasis (Drosophila melanogaster)
Platelet sensitization by LDL (Drosophila melanogaster)
Fgr may phosphorylate p38 MAPK (Drosophila melanogaster)
ADP [cytosol]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Costimulation by the CD28 family (Drosophila melanogaster)
CD28 co-stimulation (Drosophila melanogaster)
CD28 dependent PI3K/Akt signaling (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
ADP [cytosol]
Rap1 signalling (Drosophila melanogaster)
PKA/PKG phosphorylate Rap1GAP2 (Drosophila melanogaster)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Drosophila melanogaster)
Downstream signaling events of B Cell Receptor (BCR) (Drosophila melanogaster)
Activation of NF-kappaB in B cells (Drosophila melanogaster)
Activated IKK phosphorylates I-kappaB (Drosophila melanogaster)
ADP [cytosol]
TCR signaling (Drosophila melanogaster)
Downstream TCR signaling (Drosophila melanogaster)
Phosphorylation of PKC theta (Drosophila melanogaster)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)
ADP [cytosol]
Generation of second messenger molecules (Drosophila melanogaster)
Phosphorylation of PLC-gamma1 (Drosophila melanogaster)
ADP [cytosol]
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Antiviral mechanism by IFN-stimulated genes (Drosophila melanogaster)
PKR-mediated signaling (Drosophila melanogaster)
p-PKR dimer phosphorylates CDK1 (Drosophila melanogaster)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Drosophila melanogaster)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Drosophila melanogaster)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Drosophila melanogaster)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Drosophila melanogaster)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Drosophila melanogaster)
ADP [cytosol]
Interferon gamma signaling (Drosophila melanogaster)
JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)
ADP [cytosol]
Signaling by Interleukins (Drosophila melanogaster)
Interleukin-1 family signaling (Drosophila melanogaster)
Interleukin-1 signaling (Drosophila melanogaster)
IKBA is phosphorylated by Phospho IKKB kinase (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Drosophila melanogaster)
ADP [cytosol]
Interleukin-37 signaling (Drosophila melanogaster)
STAT3 phosphorylation (Drosophila melanogaster)
ADP [cytosol]
TBK1 phosphorylation (Drosophila melanogaster)
ADP [cytosol]
Interleukin-38 signaling (Drosophila melanogaster)
MAPK8 phosphorylation (Drosophila melanogaster)
ADP [cytosol]
Interleukin-17 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Drosophila melanogaster)
NIK-->noncanonical NF-kB signaling (Drosophila melanogaster)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Drosophila melanogaster)
ADP [cytosol]
Innate Immune System (Drosophila melanogaster)
C-type lectin receptors (CLRs) (Drosophila melanogaster)
CD209 (DC-SIGN) signaling (Drosophila melanogaster)
PAK phosphorylates p21 RAF1 on S338 (Drosophila melanogaster)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Drosophila melanogaster)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Drosophila melanogaster)
Dectin-1 mediated noncanonical NF-kB signaling (Drosophila melanogaster)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Drosophila melanogaster)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)
ADP [cytosol]
Dectin-2 family (Drosophila melanogaster)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Drosophila melanogaster)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Drosophila melanogaster)
STING mediated induction of host immune responses (Drosophila melanogaster)
STAT6-mediated induction of chemokines (Drosophila melanogaster)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Drosophila melanogaster)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Drosophila melanogaster)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Drosophila melanogaster)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Drosophila melanogaster)
RIP-mediated NFkB activation via ZBP1 (Drosophila melanogaster)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
DAP12 interactions (Drosophila melanogaster)
DAP12 signaling (Drosophila melanogaster)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Drosophila melanogaster)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Drosophila melanogaster)
TRAF6 mediated NF-kB activation (Drosophila melanogaster)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Drosophila melanogaster)
Autophosphorylation of LYN kinase (Drosophila melanogaster)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Drosophila melanogaster)
Autophosphorylation of BTK/ITK (Drosophila melanogaster)
ADP [cytosol]
FCERI mediated MAPK activation (Drosophila melanogaster)
Autophosphorylation of PAK (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation and activation of VAV (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
FCERI mediated NF-kB activation (Drosophila melanogaster)
Autophosphorylation of PKC-theta (Drosophila melanogaster)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Drosophila melanogaster)
Phosphorylation of PIP2 to PIP3 by PI3K (Drosophila melanogaster)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Drosophila melanogaster)
Regulation of actin dynamics for phagocytic cup formation (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
ADP [cytosol]
Autophosphorylation of PAK1 (Drosophila melanogaster)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Drosophila melanogaster)
Mother filament:ARP2/3:actin:ADP [cytosol] (Drosophila melanogaster)
Actin:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:ARP2/3:actin:ADP [cytosol] (Drosophila melanogaster)
Actin:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Drosophila melanogaster)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Drosophila melanogaster)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
ADP [cytosol]
Role of phospholipids in phagocytosis (Drosophila melanogaster)
DAG stimulates protein kinase C-delta (Drosophila melanogaster)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Drosophila melanogaster)
NOD1/2 Signaling Pathway (Drosophila melanogaster)
Activation of p38 MAPK (Drosophila melanogaster)
ADP [cytosol]
Toll-like Receptor Cascades (Drosophila melanogaster)
Toll Like Receptor 10 (TLR10) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Drosophila melanogaster)
Toll Like Receptor TLR1:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Drosophila melanogaster)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Drosophila melanogaster)
MyD88-independent TLR4 cascade (Drosophila melanogaster)
TRIF (TICAM1)-mediated TLR4 signaling (Drosophila melanogaster)
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Drosophila melanogaster)
MyD88 cascade initiated on plasma membrane (Drosophila melanogaster)
IRAK1 recruits IKK complex (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Drosophila melanogaster)
MyD88 dependent cascade initiated on endosome (Drosophila melanogaster)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Drosophila melanogaster)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Drosophila melanogaster)
ADP [cytosol]
MAP kinase activation (Drosophila melanogaster)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
ADP [cytosol]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Drosophila melanogaster)
Mitochondrial Uncoupling (Drosophila melanogaster)
The proton buffering model (Drosophila melanogaster)
Protons are translocated from the intermembrane space to the matrix (Drosophila melanogaster)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Drosophila melanogaster)
Phase II - Conjugation of compounds (Drosophila melanogaster)
Cytosolic sulfonation of small molecules (Drosophila melanogaster)
Transport and synthesis of PAPS (Drosophila melanogaster)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Drosophila melanogaster)
ADP [cytosol]
Glutathione conjugation (Drosophila melanogaster)
Glutathione synthesis and recycling (Drosophila melanogaster)
GCL ligates L-Glu to L-Cys (Drosophila melanogaster)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Drosophila melanogaster)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Drosophila melanogaster)
ADP [cytosol]
Inositol phosphate metabolism (Drosophila melanogaster)
Synthesis of IP3 and IP4 in the cytosol (Drosophila melanogaster)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Drosophila melanogaster)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Drosophila melanogaster)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Drosophila melanogaster)
ADP [cytosol]
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Drosophila melanogaster)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Glutamate and glutamine metabolism (Drosophila melanogaster)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Drosophila melanogaster)
ADP [cytosol]
Metabolism of carbohydrates (Drosophila melanogaster)
Formation of xylulose-5-phosphate (Drosophila melanogaster)
XYLB phosphorylates D-xylulose (Drosophila melanogaster)
ADP [cytosol]
Fructose metabolism (Drosophila melanogaster)
Fructose catabolism (Drosophila melanogaster)
GLYCTK phosphorylates DGA to 3PDGA (Drosophila melanogaster)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Drosophila melanogaster)
ADP [cytosol]
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Drosophila melanogaster)
ADP [cytosol]
Glycolysis (Drosophila melanogaster)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Drosophila melanogaster)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Drosophila melanogaster)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Drosophila melanogaster)
ADP [cytosol]
Glycogen metabolism (Drosophila melanogaster)
Glycogen breakdown (glycogenolysis) (Drosophila melanogaster)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Drosophila melanogaster)
ADP [cytosol]
Glycosaminoglycan metabolism (Drosophila melanogaster)
Transport and synthesis of PAPS (Drosophila melanogaster)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Drosophila melanogaster)
ADP [cytosol]
Pentose phosphate pathway (Drosophila melanogaster)
RBKS phosphorylates ribose to R5P (Drosophila melanogaster)
ADP [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine metabolism (Drosophila melanogaster)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Drosophila melanogaster)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Drosophila melanogaster)
ADP [cytosol]
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Recycling of bile acids and salts (Drosophila melanogaster)
ABCC3 transports bile salts from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
Cholesterol biosynthesis (Drosophila melanogaster)
MVD decarboxylates MVA5PP to IPPP (Drosophila melanogaster)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Drosophila melanogaster)
ADP [cytosol]
Phospholipid metabolism (Drosophila melanogaster)
Glycerophospholipid biosynthesis (Drosophila melanogaster)
Synthesis of PC (Drosophila melanogaster)
Cho is phosphorylated to PCho by CHK dimer (Drosophila melanogaster)
ADP [cytosol]
Synthesis of PE (Drosophila melanogaster)
ETA is phosphorylated to PETA by CHK/ETNK (Drosophila melanogaster)
ADP [cytosol]
PI Metabolism (Drosophila melanogaster)
Synthesis of PIPs at the ER membrane (Drosophila melanogaster)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Drosophila melanogaster)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Drosophila melanogaster)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Drosophila melanogaster)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Drosophila melanogaster)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Drosophila melanogaster)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Drosophila melanogaster)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Drosophila melanogaster)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Drosophila melanogaster)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Drosophila melanogaster)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Drosophila melanogaster)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Drosophila melanogaster)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Drosophila melanogaster)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Drosophila melanogaster)
BMX phosphorylates RUFY1 (Drosophila melanogaster)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
Sphingolipid metabolism (Drosophila melanogaster)
Glycosphingolipid metabolism (Drosophila melanogaster)
Glycosphingolipid biosynthesis (Drosophila melanogaster)
CERK phosphorylates CERA to form C1P (Drosophila melanogaster)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Drosophila melanogaster)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Drosophila melanogaster)
ADP [cytosol]
CSNK1G2 phosphorylates p-CERT1-2 (Drosophila melanogaster)
ADP [cytosol]
PRKD1,2,3 phosphorylates CERT1-2 (Drosophila melanogaster)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Drosophila melanogaster)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Drosophila melanogaster)
ADP [cytosol]
Triglyceride metabolism (Drosophila melanogaster)
Triglyceride biosynthesis (Drosophila melanogaster)
Conversion of Glycerol to Glycerol-3-phosphate (Drosophila melanogaster)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
eNOS activation (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
ADP [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Drosophila melanogaster)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Drosophila melanogaster)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Drosophila melanogaster)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Drosophila melanogaster)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Drosophila melanogaster)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Drosophila melanogaster)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Drosophila melanogaster)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Drosophila melanogaster)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Drosophila melanogaster)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Drosophila melanogaster)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Drosophila melanogaster)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Drosophila melanogaster)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Drosophila melanogaster)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Drosophila melanogaster)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Drosophila melanogaster)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Drosophila melanogaster)
ADP [cytosol]
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Drosophila melanogaster)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Drosophila melanogaster)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Drosophila melanogaster)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Drosophila melanogaster)
ADP [cytosol]
Pyrimidine biosynthesis (Drosophila melanogaster)
CAD hexamer transforms L-Gln to CAP (Drosophila melanogaster)
ADP [cytosol]
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Drosophila melanogaster)
ADP [cytosol]
Pyrimidine salvage (Drosophila melanogaster)
UCKL1 phosphorylates urindine, cytidine (Drosophila melanogaster)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Drosophila melanogaster)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Drosophila melanogaster)
ADP [cytosol]
Metabolism of porphyrins (Drosophila melanogaster)
Heme biosynthesis (Drosophila melanogaster)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
Heme degradation (Drosophila melanogaster)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Drosophila melanogaster)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Drosophila melanogaster)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Drosophila melanogaster)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Drosophila melanogaster)
Transport of RCbl within the body (Drosophila melanogaster)
ABCC1 transports cytosolic RCbl to extracellular region (Drosophila melanogaster)
ADP [cytosol]
Metabolism of folate and pterines (Drosophila melanogaster)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Drosophila melanogaster)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Drosophila melanogaster)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Drosophila melanogaster)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Drosophila melanogaster)
ADP [cytosol]
Nicotinate metabolism (Drosophila melanogaster)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Drosophila melanogaster)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Drosophila melanogaster)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Drosophila melanogaster)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Drosophila melanogaster)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Drosophila melanogaster)
RFK:Mg2+ phosphorylates RIB (Drosophila melanogaster)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Drosophila melanogaster)
Coenzyme A biosynthesis (Drosophila melanogaster)
DCAKD phosphorylates DP-CoA (Drosophila melanogaster)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Drosophila melanogaster)
ADP [cytosol]
PANK2 phosphorylates PanK (Drosophila melanogaster)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Drosophila melanogaster)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Drosophila melanogaster)
2xPDKX:2xZn2+ phosphorylates PDX (Drosophila melanogaster)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Drosophila melanogaster)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Drosophila melanogaster)
ADP [cytosol]
Metabolism of RNA (Drosophila melanogaster)
Nonsense-Mediated Decay (NMD) (Drosophila melanogaster)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Drosophila melanogaster)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Drosophila melanogaster)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Drosophila melanogaster)
MK2 phosphorylates BRF1 (Drosophila melanogaster)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Drosophila melanogaster)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Drosophila melanogaster)
Protein Kinase B (AKT) phosphorylates KSRP (Drosophila melanogaster)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Drosophila melanogaster)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Drosophila melanogaster)
ADP [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
Synthesis of substrates in N-glycan biosythesis (Drosophila melanogaster)
Synthesis of Dolichyl-phosphate (Drosophila melanogaster)
MVD decarboxylates MVA5PP to IPPP (Drosophila melanogaster)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Drosophila melanogaster)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Drosophila melanogaster)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Drosophila melanogaster)
ER to Golgi Anterograde Transport (Drosophila melanogaster)
COPI-mediated anterograde transport (Drosophila melanogaster)
GBF1 stimulates ARF nucleotide exchange (Drosophila melanogaster)
ADP [cytosol]
Protein folding (Drosophila melanogaster)
Chaperonin-mediated protein folding (Drosophila melanogaster)
Association of TriC/CCT with target proteins during biosynthesis (Drosophila melanogaster)
Association of CCT/TriC with sphingosine kinase 1 (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Drosophila melanogaster)
ATP binds G-protein beta associated TRiC/CCT (Drosophila melanogaster)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Drosophila melanogaster)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
CK2 phosphorylates PDCL (Drosophila melanogaster)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Drosophila melanogaster)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Drosophila melanogaster)
GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Drosophila melanogaster)
GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Drosophila melanogaster)
GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Drosophila melanogaster)
GNB5:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Surfactant metabolism (Drosophila melanogaster)
ABCA3 transports PC, PG from ER membrane to lamellar body (Drosophila melanogaster)
ADP [cytosol]
Translation (Drosophila melanogaster)
Eukaryotic Translation Initiation (Drosophila melanogaster)
Cap-dependent Translation Initiation (Drosophila melanogaster)
Ribosomal scanning and start codon recognition (Drosophila melanogaster)
Ribosomal scanning (Drosophila melanogaster)
ADP [cytosol]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
PRKACA phosphorylates TNNI3 (Drosophila melanogaster)
ADP [cytosol]
Smooth Muscle Contraction (Drosophila melanogaster)
ATP Hydrolysis By Myosin (Drosophila melanogaster)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Drosophila melanogaster)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Release Of ADP From Myosin (Drosophila melanogaster)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Drosophila melanogaster)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Drosophila melanogaster)
Trafficking of AMPA receptors (Drosophila melanogaster)
Trafficking of GluR2-containing AMPA receptors (Drosophila melanogaster)
Endocytosis of Ca impermeable AMPA receptors (Drosophila melanogaster)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Drosophila melanogaster)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Drosophila melanogaster)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Drosophila melanogaster)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Drosophila melanogaster)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Drosophila melanogaster)
ADP [cytosol]
Programmed Cell Death (Drosophila melanogaster)
Apoptosis (Drosophila melanogaster)
Intrinsic Pathway for Apoptosis (Drosophila melanogaster)
Apoptotic factor-mediated response (Drosophila melanogaster)
Cytochrome c-mediated apoptotic response (Drosophila melanogaster)
Activation of caspases through apoptosome-mediated cleavage (Drosophila melanogaster)
Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)
ADP [cytosol]
Formation of apoptosome (Drosophila melanogaster)
CYCS binds to APAF1 (Drosophila melanogaster)
ADP [cytosol]
APAF1:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Drosophila melanogaster)
ADP [cytosol]
Regulation of the apoptosome activity (Drosophila melanogaster)
APAF1 binds AVEN (Drosophila melanogaster)
APAF1:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
APAF1:AVEN [cytosol] (Drosophila melanogaster)
APAF1:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Drosophila melanogaster)
ADP [cytosol]
Sensory Perception (Drosophila melanogaster)
Visual phototransduction (Drosophila melanogaster)
The canonical retinoid cycle in rods (twilight vision) (Drosophila melanogaster)
ABCA4 mediates atRAL transport (Drosophila melanogaster)
ADP [cytosol]
Signal Transduction (Drosophila melanogaster)
Death Receptor Signaling (Drosophila melanogaster)
TNF signaling (Drosophila melanogaster)
Regulation of TNFR1 signaling (Drosophila melanogaster)
CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Drosophila melanogaster)
Cell death signalling via NRAGE, NRIF and NADE (Drosophila melanogaster)
NRAGE signals death through JNK (Drosophila melanogaster)
GTP-bound RAC contributes to JNK activation (Drosophila melanogaster)
ADP [cytosol]
Integrin signaling (Drosophila melanogaster)
Autophosphorylation of SRC (Drosophila melanogaster)
ADP [cytosol]
SYK activation by SRC (Drosophila melanogaster)
ADP [cytosol]
Intracellular signaling by second messengers (Drosophila melanogaster)
DAG and IP3 signaling (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
PKC phosphorylates GRK2 (Drosophila melanogaster)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Drosophila melanogaster)
ADP [cytosol]
PIP3 activates AKT signaling (Drosophila melanogaster)
AKT phosphorylates targets in the cytosol (Drosophila melanogaster)
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
ADP [cytosol]
AKT phosphorylates IKKalpha (Drosophila melanogaster)
ADP [cytosol]
AKT phosphorylates MKRN1 (Drosophila melanogaster)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
ADP [cytosol]
AKT phosphorylates caspase-9 (Drosophila melanogaster)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Drosophila melanogaster)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Drosophila melanogaster)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Drosophila melanogaster)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
PTEN Regulation (Drosophila melanogaster)
Regulation of PTEN gene transcription (Drosophila melanogaster)
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
ADP [cytosol]
Regulation of PTEN stability and activity (Drosophila melanogaster)
AKT phosphorylates MKRN1 (Drosophila melanogaster)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Drosophila melanogaster)
ADP [cytosol]
FRK phosphorylates PTEN (Drosophila melanogaster)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
ADP [cytosol]
MAPK family signaling cascades (Drosophila melanogaster)
MAPK1/MAPK3 signaling (Drosophila melanogaster)
RAF-independent MAPK1/3 activation (Drosophila melanogaster)
MAPK1 (ERK2) activation (Drosophila melanogaster)
MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)
ADP [cytosol]
MAPK3 (ERK1) activation (Drosophila melanogaster)
Inactivation of MAP2K1 by CDK1 (Drosophila melanogaster)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)
ADP [cytosol]
RAF/MAP kinase cascade (Drosophila melanogaster)
MAP2K and MAPK activation (Drosophila melanogaster)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Drosophila melanogaster)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Drosophila melanogaster)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of MAPK pathway (Drosophila melanogaster)
MAPK12 phosphorylates PTPN3 (Drosophila melanogaster)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Drosophila melanogaster)
Activated MAPK phosphorylates RAF1 (Drosophila melanogaster)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Drosophila melanogaster)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Drosophila melanogaster)
ADP [cytosol]
RAF activation (Drosophila melanogaster)
MARK3 phosphorylates KSR1 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of RAF (Drosophila melanogaster)
ADP [cytosol]
RAS processing (Drosophila melanogaster)
KRAS4B is phosphorylated on serine 181 (Drosophila melanogaster)
ADP [cytosol]
MAPK6/MAPK4 signaling (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
ADP [cytosol]
MTOR signalling (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Drosophila melanogaster)
Phosphorylation of TSC2 by PKB (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Drosophila melanogaster)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
ADP [cytosol]
mTORC1-mediated signalling (Drosophila melanogaster)
Phosphorylation and activation of eIF4G by activated S6K1 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Drosophila melanogaster)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
ADP [cytosol]
Signaling by Erythropoietin (Drosophila melanogaster)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Drosophila melanogaster)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Drosophila melanogaster)
ADP [cytosol]
Opioid Signalling (Drosophila melanogaster)
DARPP-32 events (Drosophila melanogaster)
PKA phosphorylates PDE4B (Drosophila melanogaster)
ADP [cytosol]
G-protein mediated events (Drosophila melanogaster)
PLC beta mediated events (Drosophila melanogaster)
Ca-dependent events (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
PKC phosphorylates GRK2 (Drosophila melanogaster)
ADP [cytosol]
G alpha (q) signalling events (Drosophila melanogaster)
Effects of PIP2 hydrolysis (Drosophila melanogaster)
DAG kinase produces phosphatidic acid from DAG (Drosophila melanogaster)
ADP [cytosol]
G alpha (s) signalling events (Drosophila melanogaster)
ADRB2 in ADRB2:GRK complex is phosphorylated (Drosophila melanogaster)
ADP [cytosol]
G-protein beta:gamma signalling (Drosophila melanogaster)
G beta:gamma signalling through PI3Kgamma (Drosophila melanogaster)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by Hedgehog (Drosophila melanogaster)
Hedgehog 'off' state (Drosophila melanogaster)
GLI3 is processed to GLI3R by the proteasome (Drosophila melanogaster)
CK1 phosphorylates p-GLI3 (Drosophila melanogaster)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Drosophila melanogaster)
ADP [cytosol]
PKA phosphorylates GLI3 (Drosophila melanogaster)
ADP [cytosol]
Hedgehog ligand biogenesis (Drosophila melanogaster)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Drosophila melanogaster)
ADP [cytosol]
Signaling by Hippo (Drosophila melanogaster)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Drosophila melanogaster)
ADP [cytosol]
Signaling by NOTCH (Drosophila melanogaster)
Signaling by NOTCH4 (Drosophila melanogaster)
Negative regulation of NOTCH4 signaling (Drosophila melanogaster)
AKT1 phosphorylates NOTCH4 (Drosophila melanogaster)
ADP [cytosol]
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
ESR-associated SRC autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Drosophila melanogaster)
PRKCZ autophosphorylates downstream of estrogen stimulation (Drosophila melanogaster)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by ALK (Drosophila melanogaster)
PI3K synthesizes PIP3 downstream of ALK (Drosophila melanogaster)
ADP [cytosol]
Signaling by EGFR (Drosophila melanogaster)
EGFR autophosphorylation (Drosophila melanogaster)
ADP [cytosol]
EGFR downregulation (Drosophila melanogaster)
EGFR phosphorylates EPS15 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Drosophila melanogaster)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Drosophila melanogaster)
EGFR activates PLC-gamma1 by phosphorylation (Drosophila melanogaster)
ADP [cytosol]
GAB1 signalosome (Drosophila melanogaster)
GAB1 phosphorylation by EGFR kinase (Drosophila melanogaster)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Drosophila melanogaster)
ADP [cytosol]
SHC1 events in EGFR signaling (Drosophila melanogaster)
SHC1 phosphorylation by phosphorylated EGFR (Drosophila melanogaster)
ADP [cytosol]
Signaling by ERBB2 (Drosophila melanogaster)
Downregulation of ERBB2 signaling (Drosophila melanogaster)
Downregulation of ERBB2:ERBB3 signaling (Drosophila melanogaster)
Phosphorylation of USP8 by P-AKT (Drosophila melanogaster)
ADP [cytosol]
PI3K events in ERBB2 signaling (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Drosophila melanogaster)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Drosophila melanogaster)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Drosophila melanogaster)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Drosophila melanogaster)
Activated PKC phosphorylates SHC1 (Drosophila melanogaster)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Drosophila melanogaster)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Drosophila melanogaster)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Drosophila melanogaster)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Drosophila melanogaster)
ADP [cytosol]
Signaling by ERBB4 (Drosophila melanogaster)
PI3K events in ERBB4 signaling (Drosophila melanogaster)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Drosophila melanogaster)
Phosphorylation of SHC1 by ERBB4 homodimers (Drosophila melanogaster)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Drosophila melanogaster)
ADP [cytosol]
Signaling by FGFR (Drosophila melanogaster)
Signaling by FGFR1 (Drosophila melanogaster)
Downstream signaling of activated FGFR1 (Drosophila melanogaster)
FRS-mediated FGFR1 signaling (Drosophila melanogaster)
Activated FGFR1 phosphorylates FRS2 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Drosophila melanogaster)
ADP [cytosol]
PI-3K cascade:FGFR1 (Drosophila melanogaster)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Drosophila melanogaster)
Activated FGFR1 phosphorylates PLCG1 (Drosophila melanogaster)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Drosophila melanogaster)
Activated FGFR1 phosphorylates SHC1 (Drosophila melanogaster)
ADP [cytosol]
FGFR1 ligand binding and activation (Drosophila melanogaster)
FGFR1b ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR1b (Drosophila melanogaster)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Drosophila melanogaster)
ADP [cytosol]
FGFR1c ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR1c (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Drosophila melanogaster)
ADP [cytosol]
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is phosphorylated by phosphorylated MNK1 (Drosophila melanogaster)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Drosophila melanogaster)
ADP [cytosol]
Signaling by FGFR2 (Drosophila melanogaster)
Downstream signaling of activated FGFR2 (Drosophila melanogaster)
FRS-mediated FGFR2 signaling (Drosophila melanogaster)
Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Drosophila melanogaster)
ADP [cytosol]
PI-3K cascade:FGFR2 (Drosophila melanogaster)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Drosophila melanogaster)
Activated FGFR2 phosphorylates PLCG1 (Drosophila melanogaster)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Drosophila melanogaster)
Activated FGFR2 phosphorylates SHC1 (Drosophila melanogaster)
ADP [cytosol]
FGFR2 ligand binding and activation (Drosophila melanogaster)
FGFR2b ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR2b (Drosophila melanogaster)
ADP [cytosol]
FGFR2c ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR2c (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Drosophila melanogaster)
ADP [cytosol]
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is phosphorylated by phosphorylated MNK1 (Drosophila melanogaster)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Drosophila melanogaster)
ADP [cytosol]
Signaling by FGFR3 (Drosophila melanogaster)
Downstream signaling of activated FGFR3 (Drosophila melanogaster)
FRS-mediated FGFR3 signaling (Drosophila melanogaster)
Activated FGFR3 phosphorylates FRS2 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Drosophila melanogaster)
ADP [cytosol]
PI-3K cascade:FGFR3 (Drosophila melanogaster)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Drosophila melanogaster)
Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Drosophila melanogaster)
Activated FGFR3 phosphorylates SHC1 (Drosophila melanogaster)
ADP [cytosol]
FGFR3 ligand binding and activation (Drosophila melanogaster)
FGFR3b ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR3b (Drosophila melanogaster)
ADP [cytosol]
FGFR3c ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR3c (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Drosophila melanogaster)
ADP [cytosol]
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is phosphorylated by phosphorylated MNK1 (Drosophila melanogaster)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Drosophila melanogaster)
ADP [cytosol]
Signaling by FGFR4 (Drosophila melanogaster)
Downstream signaling of activated FGFR4 (Drosophila melanogaster)
FRS-mediated FGFR4 signaling (Drosophila melanogaster)
Activated FGFR4 phosphorylates FRS2 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Drosophila melanogaster)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Drosophila melanogaster)
ADP [cytosol]
PI-3K cascade:FGFR4 (Drosophila melanogaster)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Drosophila melanogaster)
Activated FGFR4 phosphorylates PLCG1 (Drosophila melanogaster)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Drosophila melanogaster)
Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)
ADP [cytosol]
FGFR4 ligand binding and activation (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR4 (Drosophila melanogaster)
ADP [cytosol]
betaKlotho-mediated ligand binding (Drosophila melanogaster)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Drosophila melanogaster)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Drosophila melanogaster)
ADP [cytosol]
Spry regulation of FGF signaling (Drosophila melanogaster)
SPRY2 is phosphorylated by phosphorylated MNK1 (Drosophila melanogaster)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Drosophila melanogaster)
ADP [cytosol]
Signaling by Insulin receptor (Drosophila melanogaster)
Insulin receptor signalling cascade (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
Activation of AKT2 (Drosophila melanogaster)
PDPK1 phosphorylates AKT2 (Drosophila melanogaster)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Signal attenuation (Drosophila melanogaster)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Drosophila melanogaster)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Drosophila melanogaster)
ADP [cytosol]
Signaling by NTRKs (Drosophila melanogaster)
Signaling by NTRK1 (TRKA) (Drosophila melanogaster)
PI3K/AKT activation (Drosophila melanogaster)
PI3K produces PIP3 and other phosphatidyl inositides (Drosophila melanogaster)
ADP [cytosol]
Signalling to ERKs (Drosophila melanogaster)
Prolonged ERK activation events (Drosophila melanogaster)
Frs2-mediated activation (Drosophila melanogaster)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Drosophila melanogaster)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Drosophila melanogaster)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)
ADP [cytosol]
Signalling to RAS (Drosophila melanogaster)
p38MAPK events (Drosophila melanogaster)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by PDGF (Drosophila melanogaster)
Autophosphorylation of PDGF alpha receptors (Drosophila melanogaster)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Drosophila melanogaster)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Drosophila melanogaster)
ADP [cytosol]
Downstream signal transduction (Drosophila melanogaster)
Activation of Src (Drosophila melanogaster)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Drosophila melanogaster)
ADP [cytosol]
Signaling by SCF-KIT (Drosophila melanogaster)
Phosphorylation of JAK2 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of STATs (Drosophila melanogaster)
ADP [cytosol]
Regulation of KIT signaling (Drosophila melanogaster)
PKC alpha interacts with and phosphorylates KIT (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of APS (Drosophila melanogaster)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Drosophila melanogaster)
IGF1R signaling cascade (Drosophila melanogaster)
IRS-related events triggered by IGF1R (Drosophila melanogaster)
IRS-mediated signalling (Drosophila melanogaster)
PI3K Cascade (Drosophila melanogaster)
Activation of AKT2 (Drosophila melanogaster)
PDPK1 phosphorylates AKT2 (Drosophila melanogaster)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
FYN autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
FYN phosphorylates PAK2 (Drosophila melanogaster)
ADP [cytosol]
PAK2 autophorylates (Drosophila melanogaster)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Drosophila melanogaster)
PDK1 phosphorylates PKC (Drosophila melanogaster)
ADP [cytosol]
PKC autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Drosophila melanogaster)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
ADP [cytosol]
PAK1-3 autophosphorylates (Drosophila melanogaster)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Drosophila melanogaster)
ADP [cytosol]
p38 MAPK activation by VEGFR (Drosophila melanogaster)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Drosophila melanogaster)
RHOBTB3 ATPase cycle (Drosophila melanogaster)
RHOBTB3 hydrolyzes ATP (Drosophila melanogaster)
RHOBTB3:ADP [trans-Golgi network membrane] (Drosophila melanogaster)
ADP [cytosol]
Signaling by Rho GTPases (Drosophila melanogaster)
RHO GTPase Effectors (Drosophila melanogaster)
RHO GTPases Activate NADPH Oxidases (Drosophila melanogaster)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Drosophila melanogaster)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Drosophila melanogaster)
ABL phosphorylates WAVEs (Drosophila melanogaster)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Drosophila melanogaster)
Mother filament:ARP2/3:actin:ADP [cytosol] (Drosophila melanogaster)
Actin:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
Detachment of WASP/WAVE (Drosophila melanogaster)
Mother filament:ARP2/3:actin:ADP [cytosol] (Drosophila melanogaster)
Actin:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
ADP [cytosol]
RHO GTPases activate PAKs (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
ADP [cytosol]
PAK1 phosphorylates FLNA (Drosophila melanogaster)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Drosophila melanogaster)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Drosophila melanogaster)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Drosophila melanogaster)
ADP [cytosol]
RHO GTPases activate PKNs (Drosophila melanogaster)
PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Drosophila melanogaster)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Drosophila melanogaster)
ADP [cytosol]
Signaling by TGFB family members (Drosophila melanogaster)
Signaling by Activin (Drosophila melanogaster)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Drosophila melanogaster)
ADP [cytosol]
Signaling by BMP (Drosophila melanogaster)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Drosophila melanogaster)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Drosophila melanogaster)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Drosophila melanogaster)
TGF-beta receptor signaling activates SMADs (Drosophila melanogaster)
Activated type I receptor phosphorylates SMAD2/3 directly (Drosophila melanogaster)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Drosophila melanogaster)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Drosophila melanogaster)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Drosophila melanogaster)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Drosophila melanogaster)
ADP [cytosol]
Signaling by WNT (Drosophila melanogaster)
Beta-catenin independent WNT signaling (Drosophila melanogaster)
Ca2+ pathway (Drosophila melanogaster)
Activation of NLK (Drosophila melanogaster)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Drosophila melanogaster)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Drosophila melanogaster)
AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Drosophila melanogaster)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
ADP [cytosol]
TCF dependent signaling in response to WNT (Drosophila melanogaster)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Drosophila melanogaster)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Drosophila melanogaster)
ADP [cytosol]
WNT mediated activation of DVL (Drosophila melanogaster)
CSNK2-mediated phosphorylation of DVL (Drosophila melanogaster)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Drosophila melanogaster)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Drosophila melanogaster)
ADP [cytosol]
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
ABC transporters in lipid homeostasis (Drosophila melanogaster)
ABCA12 transports lipids from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Drosophila melanogaster)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Drosophila melanogaster)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
ABCA4 mediates atRAL transport (Drosophila melanogaster)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
HCO3- transport through ion channel (Drosophila melanogaster)
ADP [cytosol]
Mitochondrial ABC transporters (Drosophila melanogaster)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Drosophila melanogaster)
ADP [cytosol]
The ABCC family mediates organic anion transport (Drosophila melanogaster)
ADP [cytosol]
Aquaporin-mediated transport (Drosophila melanogaster)
Vasopressin regulates renal water homeostasis via Aquaporins (Drosophila melanogaster)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Drosophila melanogaster)
ADP [cytosol]
Ion channel transport (Drosophila melanogaster)
Ion transport by P-type ATPases (Drosophila melanogaster)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Drosophila melanogaster)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Drosophila melanogaster)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Drosophila melanogaster)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Drosophila melanogaster)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Drosophila melanogaster)
ADP [cytosol]
Iron uptake and transport (Drosophila melanogaster)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
ADP [cytosol]
Transferrin endocytosis and recycling (Drosophila melanogaster)
Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Drosophila melanogaster)
Plasma lipoprotein assembly (Drosophila melanogaster)
HDL assembly (Drosophila melanogaster)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Drosophila melanogaster)
ADP [cytosol]
Plasma lipoprotein remodeling (Drosophila melanogaster)
HDL remodeling (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
ADP [cytosol]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Drosophila melanogaster)
ADP [cytosol]
Vesicle-mediated transport (Drosophila melanogaster)
Membrane Trafficking (Drosophila melanogaster)
Clathrin-mediated endocytosis (Drosophila melanogaster)
AAK1 phosphorylates AP-2 mu subunit at T156 (Drosophila melanogaster)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Drosophila melanogaster)
clathrin:HSPA8:ADP [cytosol] (Drosophila melanogaster)
HSPA8:ADP [cytosol] (Drosophila melanogaster)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Drosophila melanogaster)
ADP [cytosol]
ER to Golgi Anterograde Transport (Drosophila melanogaster)
COPI-mediated anterograde transport (Drosophila melanogaster)
GBF1 stimulates ARF nucleotide exchange (Drosophila melanogaster)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Drosophila melanogaster)
ESCRT Disassembly (Drosophila melanogaster)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Drosophila melanogaster)
Golgi-to-ER retrograde transport (Drosophila melanogaster)
COPI-independent Golgi-to-ER retrograde traffic (Drosophila melanogaster)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Drosophila melanogaster)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Drosophila melanogaster)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Drosophila melanogaster)
ADP [cytosol]
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Drosophila melanogaster)
RHOBTB3:ADP [trans-Golgi network membrane] (Drosophila melanogaster)
ADP [cytosol]
Rab regulation of trafficking (Drosophila melanogaster)
RAB GEFs exchange GTP for GDP on RABs (Drosophila melanogaster)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Drosophila melanogaster)
ADP [cytosol]
Autophagy (Gallus gallus)
Macroautophagy (Gallus gallus)
AMPK (complex) phosphorylates ULK1 (complex) (Gallus gallus)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Gallus gallus)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Gallus gallus)
ADP [cytosol]
Selective autophagy (Gallus gallus)
Mitophagy (Gallus gallus)
Receptor Mediated Mitophagy (Gallus gallus)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Gallus gallus)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Gallus gallus)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Gallus gallus)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)
ADP [cytosol]
Cell Cycle (Gallus gallus)
Cell Cycle, Mitotic (Gallus gallus)
M Phase (Gallus gallus)
Mitotic Metaphase and Anaphase (Gallus gallus)
Mitotic Anaphase (Gallus gallus)
Nuclear Envelope (NE) Reassembly (Gallus gallus)
Initiation of Nuclear Envelope (NE) Reformation (Gallus gallus)
CDK1 phosphorylates LBR (Gallus gallus)
ADP [cytosol]
Mitotic Prometaphase (Gallus gallus)
EML4 and NUDC in mitotic spindle formation (Gallus gallus)
NEK6 and NEK7 phosphorylate EML4 (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates NUDC (Gallus gallus)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Gallus gallus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Gallus gallus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Gallus gallus)
ADP [cytosol]
Mitotic Prophase (Gallus gallus)
Golgi Cisternae Pericentriolar Stack Reorganization (Gallus gallus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Gallus gallus)
ADP [cytosol]
Nuclear Envelope Breakdown (Gallus gallus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Gallus gallus)
CDK1:CCNB phosphorylates NEK9 (Gallus gallus)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Gallus gallus)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Gallus gallus)
CDK1 phosphorylates NUP98 (Gallus gallus)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Gallus gallus)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Gallus gallus)
G1 Phase (Gallus gallus)
Cyclin D associated events in G1 (Gallus gallus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Gallus gallus)
ADP [cytosol]
G1/S Transition (Gallus gallus)
Cyclin E associated events during G1/S transition (Gallus gallus)
AKT phosphorylates p21Cip1 and p27Kip1 (Gallus gallus)
ADP [cytosol]
Mitotic G2-G2/M phases (Gallus gallus)
G2/M Transition (Gallus gallus)
AURKA Activation by TPX2 (Gallus gallus)
TPX2 promotes AURKA autophosphorylation (Gallus gallus)
ADP [cytosol]
Centrosome maturation (Gallus gallus)
Loss of proteins required for interphase microtubule organization from the centrosome (Gallus gallus)
Loss of Nlp from mitotic centrosomes (Gallus gallus)
Plk1-mediated phosphorylation of Nlp (Gallus gallus)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Gallus gallus)
AURKA phosphorylates PHLDA1 (Gallus gallus)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Gallus gallus)
AJUBA facilitates AURKA autophosphorylation (Gallus gallus)
ADP [cytosol]
AURKA phosphorylates PLK1 (Gallus gallus)
ADP [cytosol]
CDK1 phosphorylates BORA (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates BORA (Gallus gallus)
ADP [cytosol]
PLK1 phosphorylates OPTN (Gallus gallus)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Gallus gallus)
PLK1 phosphorylates GTSE1 (Gallus gallus)
ADP [cytosol]
S Phase (Gallus gallus)
Cyclin A:Cdk2-associated events at S phase entry (Gallus gallus)
AKT phosphorylates p21Cip1 and p27Kip1 (Gallus gallus)
ADP [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular Senescence (Gallus gallus)
Oxidative Stress Induced Senescence (Gallus gallus)
MAP3K5 phosphorylates MKK3 and MKK6 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Cellular response to chemical stress (Gallus gallus)
KEAP1-NFE2L2 pathway (Gallus gallus)
Nuclear events mediated by NFE2L2 (Gallus gallus)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Gallus gallus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Gallus gallus)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Gallus gallus)
ADP [cytosol]
Cellular response to heat stress (Gallus gallus)
Regulation of HSF1-mediated heat shock response (Gallus gallus)
Constitutive phosphorylation by pERK1/2 (Gallus gallus)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Gallus gallus)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Gallus gallus)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Gallus gallus)
ATP binding to HSP90 triggers conformation change (Gallus gallus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
ATP hydrolysis by HSP70 (Gallus gallus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Gallus gallus)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Gallus gallus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Gallus gallus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Gallus gallus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Gallus gallus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Gallus gallus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Gallus gallus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Unfolded Protein Response (UPR) (Gallus gallus)
IRE1alpha activates chaperones (Gallus gallus)
IRE1 dimer autophosphorylates (Gallus gallus)
ADP [cytosol]
PERK regulates gene expression (Gallus gallus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Gallus gallus)
ADP [cytosol]
DNA Replication (Gallus gallus)
DNA Replication Pre-Initiation (Gallus gallus)
Assembly of the pre-replicative complex (Gallus gallus)
Assembly of the ORC complex at the origin of replication (Gallus gallus)
ORC6 is phosphorylated on T195 (Gallus gallus)
ADP [cytosol]
Developmental Biology (Gallus gallus)
MITF-M-regulated melanocyte development (Gallus gallus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Gallus gallus)
MAPK-dependent phosphorylation of KARS (Gallus gallus)
ADP [cytosol]
Nervous system development (Gallus gallus)
Axon guidance (Gallus gallus)
EPH-Ephrin signaling (Gallus gallus)
EPH receptors autophosphorylate (Gallus gallus)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Gallus gallus)
SFKs phosphorylate VAV2,3 (Gallus gallus)
ADP [cytosol]
EPHB-mediated forward signaling (Gallus gallus)
EPHB phosphorylates TIAM1 (Gallus gallus)
ADP [cytosol]
PAK1 autophosphorylates (Gallus gallus)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Gallus gallus)
ADP [cytosol]
Ephrin signaling (Gallus gallus)
PAKs autophosphorylate (Gallus gallus)
ADP [cytosol]
PAKs phosphorylate MLC (Gallus gallus)
ADP [cytosol]
L1CAM interactions (Gallus gallus)
Recycling pathway of L1 (Gallus gallus)
Phosphorylation of L1 by ERK (Gallus gallus)
ADP [cytosol]
Signal transduction by L1 (Gallus gallus)
Interaction of PAK1 with Rac1-GTP (Gallus gallus)
ADP [cytosol]
Netrin-1 signaling (Gallus gallus)
DCC mediated attractive signaling (Gallus gallus)
Phosphorylation of DCC by Fyn (Gallus gallus)
ADP [cytosol]
RET signaling (Gallus gallus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Gallus gallus)
ADP [cytosol]
RET tyrosine phosphorylation (Gallus gallus)
ADP [cytosol]
Reelin signalling pathway (Gallus gallus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Gallus gallus)
ADP [cytosol]
Semaphorin interactions (Gallus gallus)
CRMPs in Sema3A signaling (Gallus gallus)
Phosphorylation of CRMPs by Cdk5 (Gallus gallus)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Gallus gallus)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Gallus gallus)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Gallus gallus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Gallus gallus)
ADP [cytosol]
Sema4D in semaphorin signaling (Gallus gallus)
Sema4D induced cell migration and growth-cone collapse (Gallus gallus)
SEMA4D interacts with Plexin-B1:ErbB2 (Gallus gallus)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Gallus gallus)
SEMA4D interacts with Plexin-B1:Met (Gallus gallus)
ADP [cytosol]
Drug ADME (Gallus gallus)
Aspirin ADME (Gallus gallus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Gallus gallus)
ADP [cytosol]
Azathioprine ADME (Gallus gallus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Gallus gallus)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Gallus gallus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Gallus gallus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Gallus gallus)
ADP [cytosol]
Paracetamol ADME (Gallus gallus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Gallus gallus)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Gallus gallus)
ADP [cytosol]
Prednisone ADME (Gallus gallus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Gallus gallus)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Gallus gallus)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Gallus gallus)
ADP [cytosol]
Ribavirin ADME (Gallus gallus)
ADK phosphorylates RBV (Gallus gallus)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Gallus gallus)
ADP [cytosol]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
Regulation of TP53 Activity (Gallus gallus)
Regulation of TP53 Expression and Degradation (Gallus gallus)
Regulation of TP53 Degradation (Gallus gallus)
AKT phosphorylates MDM2 (Gallus gallus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Gallus gallus)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Gallus gallus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Gallus gallus)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Gallus gallus)
AKT phosphorylates TSC2, inhibiting it (Gallus gallus)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Gallus gallus)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Gallus gallus)
PLK2 phosphorylates CENPJ (Gallus gallus)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Gallus gallus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Gallus gallus)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Gallus gallus)
Regulation of RUNX3 expression and activity (Gallus gallus)
SRC phosphorylates RUNX3 (Gallus gallus)
ADP [cytosol]
Hemostasis (Gallus gallus)
Cell surface interactions at the vascular wall (Gallus gallus)
PECAM1 interactions (Gallus gallus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Gallus gallus)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Gallus gallus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Gallus gallus)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Gallus gallus)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Gallus gallus)
ADP [cytosol]
Kinesins (Gallus gallus)
Kinesins move along microtubules consuming ATP (Gallus gallus)
ADP [cytosol]
Platelet activation, signaling and aggregation (Gallus gallus)
Effects of PIP2 hydrolysis (Gallus gallus)
DAG kinase produces phosphatidic acid from DAG (Gallus gallus)
ADP [cytosol]
GPVI-mediated activation cascade (Gallus gallus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Gallus gallus)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Gallus gallus)
Integrin signaling (Gallus gallus)
Autophosphorylation of PTK2 at Y397 (Gallus gallus)
ADP [cytosol]
Autophosphorylation of SRC (Gallus gallus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Gallus gallus)
ADP [cytosol]
SYK activation by SRC (Gallus gallus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Gallus gallus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Gallus gallus)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Gallus gallus)
Disinhibition of SNARE formation (Gallus gallus)
Phosphorylation of Platelet Sec-1 (Gallus gallus)
ADP [cytosol]
Platelet degranulation (Gallus gallus)
ABCC4 accumulation of dense granule contents (Gallus gallus)
ADP [cytosol]
Signal amplification (Gallus gallus)
ADP signalling through P2Y purinoceptor 1 (Gallus gallus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Gallus gallus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Gallus gallus)
ADP [cytosol]
Platelet homeostasis (Gallus gallus)
Platelet sensitization by LDL (Gallus gallus)
FGR binds and phosphorylates LRP8 (Gallus gallus)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Gallus gallus)
ADP [cytosol]
PECAM1 is phosphorylated (Gallus gallus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Gallus gallus)
ADP [cytosol]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Costimulation by the CD28 family (Gallus gallus)
CD28 co-stimulation (Gallus gallus)
CD28 dependent PI3K/Akt signaling (Gallus gallus)
AKT interacts and phosphorylates Cot (Gallus gallus)
ADP [cytosol]
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Gallus gallus)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Gallus gallus)
ADP [cytosol]
CD28 dependent Vav1 pathway (Gallus gallus)
Activation of Vav1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of CD28 (Gallus gallus)
ADP [cytosol]
PD-1 signaling (Gallus gallus)
Phosphorylation of PD-1 (Gallus gallus)
ADP [cytosol]
Rap1 signalling (Gallus gallus)
PKA/PKG phosphorylate Rap1GAP2 (Gallus gallus)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Gallus gallus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Gallus gallus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Gallus gallus)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Gallus gallus)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Gallus gallus)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Gallus gallus)
Activation of NF-kappaB in B cells (Gallus gallus)
PRKCB (PKC-beta) phosphorylates CARMA1 (Gallus gallus)
ADP [cytosol]
TCR signaling (Gallus gallus)
Downstream TCR signaling (Gallus gallus)
Activation of TAK1-TAB2 complex (Gallus gallus)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of Bcl10 (Gallus gallus)
ADP [cytosol]
Generation of second messenger molecules (Gallus gallus)
Phosphorylation of PLC-gamma1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Gallus gallus)
Activation of Lck (Gallus gallus)
ADP [cytosol]
Inactivation of Lck by Csk (Gallus gallus)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Gallus gallus)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Gallus gallus)
Activation of ZAP-70 (Gallus gallus)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Gallus gallus)
ADP [cytosol]
Cytokine Signaling in Immune system (Gallus gallus)
Growth hormone receptor signaling (Gallus gallus)
JAK2 phosphorylation (Gallus gallus)
ADP [cytosol]
JAK2 phosphorylation of GHR (Gallus gallus)
ADP [cytosol]
Lyn activates ERK (Gallus gallus)
ADP [cytosol]
Interferon Signaling (Gallus gallus)
Antiviral mechanism by IFN-stimulated genes (Gallus gallus)
PKR-mediated signaling (Gallus gallus)
p-PKR dimer phosphorylates CDK1 (Gallus gallus)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Gallus gallus)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Gallus gallus)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Gallus gallus)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Gallus gallus)
ADP [cytosol]
Interferon alpha/beta signaling (Gallus gallus)
Activation of JAK kinases (Gallus gallus)
ADP [cytosol]
Formation of p-STAT1 homodimer (Gallus gallus)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Gallus gallus)
ADP [cytosol]
Phosphorylation of STAT2 (Gallus gallus)
ADP [cytosol]
Interferon gamma signaling (Gallus gallus)
IFNG signaling activates MAPKs (Gallus gallus)
JAK1-activated RAF1 phosphorylates MAPKs (Gallus gallus)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Gallus gallus)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Gallus gallus)
ADP [cytosol]
Phosphorylation of JAK2 (Gallus gallus)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Gallus gallus)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Gallus gallus)
ADP [cytosol]
Transphosphorylation of JAK1 (Gallus gallus)
ADP [cytosol]
Prolactin receptor signaling (Gallus gallus)
JAK2 phosphorylation (Gallus gallus)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Gallus gallus)
ADP [cytosol]
Signaling by Interleukins (Gallus gallus)
Interleukin-1 family signaling (Gallus gallus)
Interleukin-1 signaling (Gallus gallus)
IKBA is phosphorylated by Phospho IKKB kinase (Gallus gallus)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Gallus gallus)
ADP [cytosol]
Interleukin-37 signaling (Gallus gallus)
STAT3 phosphorylation (Gallus gallus)
ADP [cytosol]
TBK1 phosphorylation (Gallus gallus)
ADP [cytosol]
Interleukin-38 signaling (Gallus gallus)
MAPK8 phosphorylation (Gallus gallus)
ADP [cytosol]
Interleukin-10 signaling (Gallus gallus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Gallus gallus)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Gallus gallus)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Gallus gallus)
ADP [cytosol]
Interleukin-12 family signaling (Gallus gallus)
Interleukin-12 signaling (Gallus gallus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Gallus gallus)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Gallus gallus)
ADP [cytosol]
Interleukin-23 signaling (Gallus gallus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Gallus gallus)
ADP [cytosol]
Interleukin-35 Signalling (Gallus gallus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Gallus gallus)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Gallus gallus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Gallus gallus)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Gallus gallus)
ADP [cytosol]
Interleukin-17 signaling (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Interleukin-2 family signaling (Gallus gallus)
Interleukin receptor SHC signaling (Gallus gallus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Gallus gallus)
ADP [cytosol]
Interleukin-21 signaling (Gallus gallus)
IL21 receptor JAK phosphorylation (Gallus gallus)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Gallus gallus)
ADP [cytosol]
Interleukin-9 signaling (Gallus gallus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Gallus gallus)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Gallus gallus)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Gallus gallus)
ADP [cytosol]
Interleukin-20 family signaling (Gallus gallus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Gallus gallus)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Gallus gallus)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Gallus gallus)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Gallus gallus)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Gallus gallus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Gallus gallus)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Gallus gallus)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Gallus gallus)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Gallus gallus)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Gallus gallus)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Gallus gallus)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Gallus gallus)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Gallus gallus)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Gallus gallus)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Gallus gallus)
Activation of STAT5a/b by JAK2 (Gallus gallus)
ADP [cytosol]
Interleukin receptor SHC signaling (Gallus gallus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Gallus gallus)
ADP [cytosol]
JAK2 is phosphorylated, activated (Gallus gallus)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Gallus gallus)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Gallus gallus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Gallus gallus)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Gallus gallus)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Gallus gallus)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Gallus gallus)
ADP [cytosol]
Interleukin-6 family signaling (Gallus gallus)
Interleukin-6 signaling (Gallus gallus)
IL6ST is tyrosine phosphorylated (Gallus gallus)
ADP [cytosol]
JAK activation (Gallus gallus)
ADP [cytosol]
PTPN11 is phosphorylated (Gallus gallus)
ADP [cytosol]
Serine phosphorylation of STATs (Gallus gallus)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Gallus gallus)
ADP [cytosol]
Interleukin-7 signaling (Gallus gallus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Gallus gallus)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Gallus gallus)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Gallus gallus)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Gallus gallus)
NIK-->noncanonical NF-kB signaling (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)
ADP [cytosol]
NIK autophosphorylates on T559 (Gallus gallus)
ADP [cytosol]
Innate Immune System (Gallus gallus)
Alpha-protein kinase 1 signaling pathway (Gallus gallus)
ALPK1 phosphorylates TIFA (Gallus gallus)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Gallus gallus)
ADP [cytosol]
Antimicrobial peptides (Gallus gallus)
Ion influx/efflux at host-pathogen interface (Gallus gallus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Gallus gallus)
ADP [cytosol]
C-type lectin receptors (CLRs) (Gallus gallus)
CD209 (DC-SIGN) signaling (Gallus gallus)
PAK phosphorylates p21 RAF1 on S338 (Gallus gallus)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Gallus gallus)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Gallus gallus)
Dectin-1 mediated noncanonical NF-kB signaling (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Gallus gallus)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Gallus gallus)
ADP [cytosol]
DAP12 interactions (Gallus gallus)
DAP12 signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Gallus gallus)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Gallus gallus)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Gallus gallus)
ADP [cytosol]
Phosphorylation of SYK (Gallus gallus)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Gallus gallus)
Autophosphorylation of LYN kinase (Gallus gallus)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Gallus gallus)
Autophosphorylation of BTK/ITK (Gallus gallus)
ADP [cytosol]
FCERI mediated MAPK activation (Gallus gallus)
Autophosphorylation of PAK (Gallus gallus)
ADP [cytosol]
Phosphorylation and activation of VAV (Gallus gallus)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
FCERI mediated NF-kB activation (Gallus gallus)
Activation of TAK1 complex bound to pUb-TRAF6 (Gallus gallus)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Gallus gallus)
Phosphorylation of PIP2 to PIP3 by PI3K (Gallus gallus)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Gallus gallus)
FCGR activation (Gallus gallus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Gallus gallus)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
ADP [cytosol]
Autophosphorylation of PAK1 (Gallus gallus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Gallus gallus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Gallus gallus)
Actin:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Gallus gallus)
Actin:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of VAV (Gallus gallus)
ADP [cytosol]
Role of myosins in phagosome formation (Gallus gallus)
Myosin-Actin filaments [cytosol] (Gallus gallus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Gallus gallus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Gallus gallus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
ADP [cytosol]
Role of phospholipids in phagocytosis (Gallus gallus)
DAG stimulates protein kinase C-delta (Gallus gallus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phosphorylation and activation of PLCG (Gallus gallus)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Gallus gallus)
NOD1/2 Signaling Pathway (Gallus gallus)
TAK1 phosphorylates MKK6 (Gallus gallus)
ADP [cytosol]
Toll-like Receptor Cascades (Gallus gallus)
Toll Like Receptor 10 (TLR10) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
IRAK2 mediated activation of TAK1 complex (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Gallus gallus)
Toll Like Receptor TLR1:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
IRAK2 mediated activation of TAK1 complex (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Gallus gallus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
IRAK2 mediated activation of TAK1 complex (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Gallus gallus)
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Gallus gallus)
MyD88-independent TLR4 cascade (Gallus gallus)
TRIF (TICAM1)-mediated TLR4 signaling (Gallus gallus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Gallus gallus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Gallus gallus)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Gallus gallus)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Gallus gallus)
Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Gallus gallus)
IRAK2 mediated activation of TAK1 complex (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
IRAK2 mediated activation of TAK1 complex (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Gallus gallus)
MyD88 dependent cascade initiated on endosome (Gallus gallus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Gallus gallus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Gallus gallus)
ADP [cytosol]
MAP kinase activation (Gallus gallus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Gallus gallus)
MAP3K8 is phosphorylated (Gallus gallus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
ADP [cytosol]
Innate Immune System (Gallus gallus)
RLR (RIG-like receptor) mediated induction of IFN alpha/beta (Gallus gallus)
TRAF mediated activation of IRF (Gallus gallus)
Phosphorylation and release of IRF3 (Gallus gallus)
ADP [cytosol]
TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation (Gallus gallus)
ADP [cytosol]
TRAF6 mediated NF-kB activation (Gallus gallus)
Phosphorylation of IKKs complex mediated by MEKK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
Toll-like receptors (TLR) cascades (Gallus gallus)
TLR15 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 (Gallus gallus)
ADP [cytosol]
Autophosphorylation of IRAK4 bound to activated TLR5 or 15 (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
TLR2 subfamily cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
Autophosphorylation of chicken IRAK4 (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
phosphorylation of IRAK2 by activated IRAK4 (Gallus gallus)
ADP [cytosol]
TLR21 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. (Gallus gallus)
ADP [cytosol]
IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
TLR3 cascade (Gallus gallus)
IKK related kinases bound to dsRNA:TLR3:TICAM1 activate IRF3 (Gallus gallus)
Viral dsRNA:TLR3:TICAM1 Complex Activates IKBKE_CHICK (Gallus gallus)
IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
ADP [cytosol]
Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. (Gallus gallus)
ADP [cytosol]
Viral dsRNA:TLR3:TICAM1 Complex Activates TBK1 (Gallus gallus)
Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 (Gallus gallus)
ADP [cytosol]
TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
ADP [cytosol]
NFkB activation mediated by RIP1 complexed with activated TLR3 (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
chicken RIP1 facilitates IKKs complex activation (Gallus gallus)
ADP [cytosol]
TRAF6 mediated induction of proinflammatory cytokines (Gallus gallus)
Activation of recruited TAK1 (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
TLR4 cascade (Gallus gallus)
MyD88:TIRAP-dependent cascade initiated on plasma membrane (Gallus gallus)
Autophosphorylation of chicken IRAK4 (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
phosphorylation of IRAK2 by activated IRAK4 (Gallus gallus)
ADP [cytosol]
TLR5 cascade (Gallus gallus)
MyD88 cascade initiated on plasma membrane (Gallus gallus)
Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 (Gallus gallus)
ADP [cytosol]
Autophosphorylation of IRAK4 bound to activated TLR5 or 15 (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
TLR7 cascade (Gallus gallus)
MyD88-dependent cascade initiated on endosome membrane (Gallus gallus)
Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. (Gallus gallus)
ADP [cytosol]
IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex (Gallus gallus)
ADP [cytosol]
NFkB and MAPK activation mediated by TRAF6 upon TLR7 or TLR21 stimulation (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation (Gallus gallus)
ADP [cytosol]
MAPK activation in TLR cascade (Gallus gallus)
Activated TAK1 mediates Jun kinases (JNK) phosphorylation and activation (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
ADP [cytosol]
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
ADP [cytosol]
Activated TAK1 mediates p38 MAP kinase phosphorylation (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
ADP [cytosol]
ERK activation (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
ADP [cytosol]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
ADP [cytosol]
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
ADP [cytosol]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Pyruvate metabolism (Gallus gallus)
PKM dephosphorylates PEP to PYR (Gallus gallus)
ADP [cytosol]
Regulation of pyruvate metabolism (Gallus gallus)
NEK1 phosphorylates ME1 (Gallus gallus)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Gallus gallus)
Mitochondrial Uncoupling (Gallus gallus)
The proton buffering model (Gallus gallus)
Protons are translocated from the intermembrane space to the matrix (Gallus gallus)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
Transport and synthesis of PAPS (Gallus gallus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Gallus gallus)
ADP [cytosol]
Glutathione conjugation (Gallus gallus)
Glutathione synthesis and recycling (Gallus gallus)
GSS:Mg2+ dimer synthesizes GSH (Gallus gallus)
ADP [cytosol]
Inositol phosphate metabolism (Gallus gallus)
Synthesis of IP3 and IP4 in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Gallus gallus)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Gallus gallus)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Gallus gallus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Gallus gallus)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Gallus gallus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Gallus gallus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Gallus gallus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Gallus gallus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Gallus gallus)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Gallus gallus)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Gallus gallus)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Gallus gallus)
ADP [cytosol]
Integration of energy metabolism (Gallus gallus)
Regulation of insulin secretion (Gallus gallus)
Acetylcholine regulates insulin secretion (Gallus gallus)
Protein kinase C, alpha type phosphorylates MARCKS (Gallus gallus)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Gallus gallus)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Creatine metabolism (Gallus gallus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Gallus gallus)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Gallus gallus)
ADP [cytosol]
Glutamate and glutamine metabolism (Gallus gallus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Gallus gallus)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Gallus gallus)
ADP [cytosol]
Histidine catabolism (Gallus gallus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Gallus gallus)
ADP [cytosol]
Metabolism of carbohydrates (Gallus gallus)
Formation of xylulose-5-phosphate (Gallus gallus)
XYLB phosphorylates D-xylulose (Gallus gallus)
ADP [cytosol]
Fructose metabolism (Gallus gallus)
Fructose catabolism (Gallus gallus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Gallus gallus)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Gallus gallus)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Gallus gallus)
ADP [cytosol]
Galactose catabolism (Gallus gallus)
GALK1 phosphorylates Gal to Gal1P (Gallus gallus)
ADP [cytosol]
Glucose metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Gallus gallus)
ADP [cytosol]
Glycolysis (Gallus gallus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Gallus gallus)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Gallus gallus)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Gallus gallus)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Gallus gallus)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Gallus gallus)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Gallus gallus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Gallus gallus)
ADP [cytosol]
Glycosaminoglycan metabolism (Gallus gallus)
Transport and synthesis of PAPS (Gallus gallus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Gallus gallus)
ADP [cytosol]
Pentose phosphate pathway (Gallus gallus)
RBKS phosphorylates ribose to R5P (Gallus gallus)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Gallus gallus)
ADP [cytosol]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Arachidonic acid metabolism (Gallus gallus)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Gallus gallus)
ALOX5 is phosphorylated by MAPKAP2 (Gallus gallus)
ADP [cytosol]
Carnitine metabolism (Gallus gallus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Gallus gallus)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Gallus gallus)
ACLY tetramer transforms CIT to Ac-CoA (Gallus gallus)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Gallus gallus)
ADP [cytosol]
Metabolism of steroids (Gallus gallus)
Bile acid and bile salt metabolism (Gallus gallus)
Recycling of bile acids and salts (Gallus gallus)
ABCB11 transports bile salts from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
Synthesis of bile acids and bile salts (Gallus gallus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Gallus gallus)
ABCB11 transports bile salts from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
Cholesterol biosynthesis (Gallus gallus)
MVD decarboxylates MVA5PP to IPPP (Gallus gallus)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Gallus gallus)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Gallus gallus)
ADP [cytosol]
Phospholipid metabolism (Gallus gallus)
Glycerophospholipid biosynthesis (Gallus gallus)
Synthesis of PC (Gallus gallus)
Cho is phosphorylated to PCho by CHK dimer (Gallus gallus)
ADP [cytosol]
Synthesis of PE (Gallus gallus)
ETA is phosphorylated to PETA by CHK/ETNK (Gallus gallus)
ADP [cytosol]
PI Metabolism (Gallus gallus)
Synthesis of PIPs at the ER membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Gallus gallus)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Gallus gallus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Gallus gallus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Gallus gallus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Gallus gallus)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Gallus gallus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Gallus gallus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Gallus gallus)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Gallus gallus)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Gallus gallus)
BMX phosphorylates RUFY1 (Gallus gallus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Gallus gallus)
ADP [cytosol]
Sphingolipid metabolism (Gallus gallus)
Glycosphingolipid metabolism (Gallus gallus)
Glycosphingolipid biosynthesis (Gallus gallus)
CERK phosphorylates CERA to form C1P (Gallus gallus)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Gallus gallus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Gallus gallus)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Gallus gallus)
ADP [cytosol]
Triglyceride metabolism (Gallus gallus)
Triglyceride biosynthesis (Gallus gallus)
Conversion of Glycerol to Glycerol-3-phosphate (Gallus gallus)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Gallus gallus)
eNOS activation (Gallus gallus)
AKT1 phosphorylates eNOS (Gallus gallus)
ADP [cytosol]
Metabolism of nucleotides (Gallus gallus)
Interconversion of nucleotide di- and triphosphates (Gallus gallus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Gallus gallus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Gallus gallus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Gallus gallus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Gallus gallus)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Gallus gallus)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Gallus gallus)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Gallus gallus)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Gallus gallus)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Gallus gallus)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Gallus gallus)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Gallus gallus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Gallus gallus)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Gallus gallus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Gallus gallus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Gallus gallus)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Gallus gallus)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Gallus gallus)
ADP [cytosol]
Nucleotide biosynthesis (Gallus gallus)
Purine ribonucleoside monophosphate biosynthesis (Gallus gallus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Gallus gallus)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Gallus gallus)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Gallus gallus)
ADP [cytosol]
Nucleotide catabolism (Gallus gallus)
Purine catabolism (Gallus gallus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Gallus gallus)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Gallus gallus)
ADP [cytosol]
Pyrimidine catabolism (Gallus gallus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Gallus gallus)
ADP [cytosol]
Nucleotide salvage (Gallus gallus)
Purine salvage (Gallus gallus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Gallus gallus)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Gallus gallus)
ADP [cytosol]
Pyrimidine salvage (Gallus gallus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Gallus gallus)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Gallus gallus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Gallus gallus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Gallus gallus)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Gallus gallus)
ADP [cytosol]
Metabolism of porphyrins (Gallus gallus)
Heme degradation (Gallus gallus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of cofactors (Gallus gallus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Gallus gallus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Gallus gallus)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Gallus gallus)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Transport of RCbl within the body (Gallus gallus)
ABCC1 transports cytosolic RCbl to extracellular region (Gallus gallus)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Gallus gallus)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Gallus gallus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Gallus gallus)
ADP [cytosol]
Metabolism of folate and pterines (Gallus gallus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Gallus gallus)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Gallus gallus)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Gallus gallus)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Gallus gallus)
ADP [cytosol]
Nicotinate metabolism (Gallus gallus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Gallus gallus)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Gallus gallus)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Gallus gallus)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Gallus gallus)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Gallus gallus)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Gallus gallus)
RFK:Mg2+ phosphorylates RIB (Gallus gallus)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Gallus gallus)
Coenzyme A biosynthesis (Gallus gallus)
COASY phosphorylates DP-CoA (Gallus gallus)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Gallus gallus)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Gallus gallus)
ADP [cytosol]
PANK2 phosphorylates PanK (Gallus gallus)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Gallus gallus)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Gallus gallus)
2xPDKX:2xZn2+ phosphorylates PDX (Gallus gallus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Gallus gallus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Gallus gallus)
ADP [cytosol]
Metabolism of RNA (Gallus gallus)
Nonsense-Mediated Decay (NMD) (Gallus gallus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Gallus gallus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Gallus gallus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Gallus gallus)
MK2 phosphorylates BRF1 (Gallus gallus)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Gallus gallus)
ADP [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
Synthesis of substrates in N-glycan biosythesis (Gallus gallus)
Sialic acid metabolism (Gallus gallus)
GNE phosphorylates ManNAc to ManNAc-6-P (Gallus gallus)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Gallus gallus)
MVD decarboxylates MVA5PP to IPPP (Gallus gallus)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Gallus gallus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Gallus gallus)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Gallus gallus)
ER to Golgi Anterograde Transport (Gallus gallus)
COPI-mediated anterograde transport (Gallus gallus)
GBF1 stimulates ARF nucleotide exchange (Gallus gallus)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)
FN3K phosphorylates ketosamines (Gallus gallus)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Gallus gallus)
ADP [cytosol]
Protein folding (Gallus gallus)
Chaperonin-mediated protein folding (Gallus gallus)
Association of TriC/CCT with target proteins during biosynthesis (Gallus gallus)
Association of CCT/TriC with sphingosine kinase 1 (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Gallus gallus)
ATP binds G-protein beta associated TRiC/CCT (Gallus gallus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Gallus gallus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Gallus gallus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Gallus gallus)
GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Gallus gallus)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Gallus gallus)
GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Gallus gallus)
GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Gallus gallus)
GNB5:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Surfactant metabolism (Gallus gallus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Gallus gallus)
ADP [cytosol]
Translation (Gallus gallus)
Eukaryotic Translation Initiation (Gallus gallus)
Cap-dependent Translation Initiation (Gallus gallus)
Ribosomal scanning and start codon recognition (Gallus gallus)
Ribosomal scanning (Gallus gallus)
ADP [cytosol]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Ion homeostasis (Gallus gallus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)
ADP [cytosol]
Smooth Muscle Contraction (Gallus gallus)
ATP Hydrolysis By Myosin (Gallus gallus)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Gallus gallus)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Gallus gallus)
ADP [cytosol]
Release Of ADP From Myosin (Gallus gallus)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Gallus gallus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Gallus gallus)
ADP [cytosol]
Striated Muscle Contraction (Gallus gallus)
ATP Hydrolysis By Myosin (Gallus gallus)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
ADP Bound Myosin Complex [cytosol] (Gallus gallus)
ADP [cytosol]
Release Of ADP From Myosin (Gallus gallus)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Gallus gallus)
ADP Bound Myosin Complex [cytosol] (Gallus gallus)
ADP [cytosol]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Gallus gallus)
Trafficking of AMPA receptors (Gallus gallus)
Trafficking of GluR2-containing AMPA receptors (Gallus gallus)
Endocytosis of Ca impermeable AMPA receptors (Gallus gallus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Gallus gallus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Gallus gallus)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Gallus gallus)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Gallus gallus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Gallus gallus)
ADP [cytosol]
Programmed Cell Death (Gallus gallus)
Apoptosis (Gallus gallus)
Intrinsic Pathway for Apoptosis (Gallus gallus)
Activation of BH3-only proteins (Gallus gallus)
Activation of BIM and translocation to mitochondria (Gallus gallus)
Phosphorylation of BIM by JNK (Gallus gallus)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Gallus gallus)
Phosphorylation of DLC2 by MAPK8 (Gallus gallus)
ADP [cytosol]
Apoptotic factor-mediated response (Gallus gallus)
Cytochrome c-mediated apoptotic response (Gallus gallus)
Activation of caspases through apoptosome-mediated cleavage (Gallus gallus)
Cleavage of Procaspase-3 by the apoptosome (Gallus gallus)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Gallus gallus)
ADP [cytosol]
Formation of apoptosome (Gallus gallus)
CYCS binds to APAF1 (Gallus gallus)
ADP [cytosol]
APAF1:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Gallus gallus)
ADP [cytosol]
Regulation of the apoptosome activity (Gallus gallus)
APAF1 binds AVEN (Gallus gallus)
APAF1:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
APAF1:AVEN [cytosol] (Gallus gallus)
APAF1:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Gallus gallus)
ADP [cytosol]
Protein localization (Gallus gallus)
Peroxisomal protein import (Gallus gallus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Gallus gallus)
ADP [cytosol]
Sensory Perception (Gallus gallus)
Visual phototransduction (Gallus gallus)
The canonical retinoid cycle in rods (twilight vision) (Gallus gallus)
ABCA4 mediates atRAL transport (Gallus gallus)
ADP [cytosol]
The phototransduction cascade (Gallus gallus)
Inactivation, recovery and regulation of the phototransduction cascade (Gallus gallus)
GRK1,4,7 phosphorylate MII to p-MII (Gallus gallus)
ADP [cytosol]
Signal Transduction (Gallus gallus)
Death Receptor Signaling (Gallus gallus)
TNF signaling (Gallus gallus)
Regulation of TNFR1 signaling (Gallus gallus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Gallus gallus)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Gallus gallus)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Gallus gallus)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Gallus gallus)
Cell death signalling via NRAGE, NRIF and NADE (Gallus gallus)
NRAGE signals death through JNK (Gallus gallus)
GTP-bound RAC contributes to JNK activation (Gallus gallus)
ADP [cytosol]
p75NTR signals via NF-kB (Gallus gallus)
NF-kB is activated and signals survival (Gallus gallus)
IKKbeta is activated (Gallus gallus)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)
ADP [cytosol]
Integrin signaling (Gallus gallus)
Autophosphorylation of PTK2 at Y397 (Gallus gallus)
ADP [cytosol]
Autophosphorylation of SRC (Gallus gallus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Gallus gallus)
ADP [cytosol]
SYK activation by SRC (Gallus gallus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Gallus gallus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Gallus gallus)
ADP [cytosol]
Intracellular signaling by second messengers (Gallus gallus)
DAG and IP3 signaling (Gallus gallus)
CaM pathway (Gallus gallus)
Calmodulin induced events (Gallus gallus)
PKC phosphorylates GRK2 (Gallus gallus)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Gallus gallus)
ADP [cytosol]
PIP3 activates AKT signaling (Gallus gallus)
AKT phosphorylates targets in the cytosol (Gallus gallus)
AKT phosphorylates IKKalpha (Gallus gallus)
ADP [cytosol]
AKT phosphorylates MDM2 (Gallus gallus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Gallus gallus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Gallus gallus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Gallus gallus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Gallus gallus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Gallus gallus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Gallus gallus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Gallus gallus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Gallus gallus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
PTEN Regulation (Gallus gallus)
Regulation of PTEN gene transcription (Gallus gallus)
mTORC1 phosphorylates MAF1 (Gallus gallus)
ADP [cytosol]
Regulation of PTEN stability and activity (Gallus gallus)
AKT phosphorylates MKRN1 (Gallus gallus)
ADP [cytosol]
FRK phosphorylates PTEN (Gallus gallus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Gallus gallus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Gallus gallus)
ADP [cytosol]
MAPK family signaling cascades (Gallus gallus)
MAPK1/MAPK3 signaling (Gallus gallus)
RAF-independent MAPK1/3 activation (Gallus gallus)
MAPK3 (ERK1) activation (Gallus gallus)
Inactivation of MAP2K1 by CDK1 (Gallus gallus)
ADP [cytosol]
RAF/MAP kinase cascade (Gallus gallus)
MAP2K and MAPK activation (Gallus gallus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Gallus gallus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Gallus gallus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Gallus gallus)
ADP [cytosol]
Negative regulation of MAPK pathway (Gallus gallus)
MAPK12 phosphorylates PTPN3 (Gallus gallus)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Gallus gallus)
Activated MAPK phosphorylates RAF1 (Gallus gallus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Gallus gallus)
ADP [cytosol]
RAF activation (Gallus gallus)
Phosphorylation of RAF (Gallus gallus)
ADP [cytosol]
RAS processing (Gallus gallus)
KRAS4B is phosphorylated on serine 181 (Gallus gallus)
ADP [cytosol]
MAPK6/MAPK4 signaling (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
ADP [cytosol]
MAPKAPK5 phosphorylates KALRN (Gallus gallus)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Gallus gallus)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Gallus gallus)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Gallus gallus)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Gallus gallus)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Gallus gallus)
ADP [cytosol]
MTOR signalling (Gallus gallus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Gallus gallus)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Gallus gallus)
AMPK phosphorylates Raptor in the mTORC1 complex (Gallus gallus)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Gallus gallus)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Gallus gallus)
ADP [cytosol]
mTORC1-mediated signalling (Gallus gallus)
Phosphorylation and activation of eIF4B by activated S6K1 (Gallus gallus)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Gallus gallus)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Gallus gallus)
ADP [cytosol]
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Gallus gallus)
ADP [cytosol]
Opioid Signalling (Gallus gallus)
DARPP-32 events (Gallus gallus)
PKA phosphorylates DARPP-32 on Thr34 (Gallus gallus)
ADP [cytosol]
PKA phosphorylates PDE4B (Gallus gallus)
ADP [cytosol]
G-protein mediated events (Gallus gallus)
PLC beta mediated events (Gallus gallus)
Ca-dependent events (Gallus gallus)
CaM pathway (Gallus gallus)
Calmodulin induced events (Gallus gallus)
PKC phosphorylates GRK2 (Gallus gallus)
ADP [cytosol]
phospho-PLA2 pathway (Gallus gallus)
Phosphorylation of cPLA2 by ERK-2 (Gallus gallus)
ADP [cytosol]
G alpha (q) signalling events (Gallus gallus)
Effects of PIP2 hydrolysis (Gallus gallus)
DAG kinase produces phosphatidic acid from DAG (Gallus gallus)
ADP [cytosol]
G alpha (s) signalling events (Gallus gallus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Gallus gallus)
ADP [cytosol]
G-protein beta:gamma signalling (Gallus gallus)
G beta:gamma signalling through PI3Kgamma (Gallus gallus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Signaling by Hedgehog (Gallus gallus)
Hedgehog 'off' state (Gallus gallus)
GLI3 is processed to GLI3R by the proteasome (Gallus gallus)
CK1 phosphorylates p-GLI3 (Gallus gallus)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Gallus gallus)
ADP [cytosol]
PKA phosphorylates GLI3 (Gallus gallus)
ADP [cytosol]
Hedgehog ligand biogenesis (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Gallus gallus)
ADP [cytosol]
Signaling by Hippo (Gallus gallus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Gallus gallus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Gallus gallus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Gallus gallus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Gallus gallus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Gallus gallus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Gallus gallus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Gallus gallus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Gallus gallus)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Gallus gallus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Gallus gallus)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Gallus gallus)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Gallus gallus)
ADP [cytosol]
Signaling by NOTCH (Gallus gallus)
Signaling by NOTCH3 (Gallus gallus)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Gallus gallus)
EGFR phosphorylates NOTCH3 (Gallus gallus)
ADP [cytosol]
Signaling by NOTCH4 (Gallus gallus)
Negative regulation of NOTCH4 signaling (Gallus gallus)
AKT1 phosphorylates NOTCH4 (Gallus gallus)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Gallus gallus)
Signaling by PTK6 (Gallus gallus)
PTK6 promotes HIF1A stabilization (Gallus gallus)
EGFR phosphorylates GPNMB (Gallus gallus)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Gallus gallus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Gallus gallus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Gallus gallus)
ADP [cytosol]
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
ESR-associated SRC autophosphorylates (Gallus gallus)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Gallus gallus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Gallus gallus)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Gallus gallus)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by ALK (Gallus gallus)
ALK autophosphorylation (Gallus gallus)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Gallus gallus)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Gallus gallus)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Gallus gallus)
ADP [cytosol]
Signaling by EGFR (Gallus gallus)
EGFR autophosphorylation (Gallus gallus)
ADP [cytosol]
EGFR downregulation (Gallus gallus)
EGFR phosphorylates EPS15 (Gallus gallus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Gallus gallus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Gallus gallus)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Gallus gallus)
EGFR activates PLC-gamma1 by phosphorylation (Gallus gallus)
ADP [cytosol]
GAB1 signalosome (Gallus gallus)
GAB1 phosphorylation by EGFR kinase (Gallus gallus)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Gallus gallus)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Gallus gallus)
ADP [cytosol]
SHC1 events in EGFR signaling (Gallus gallus)
SHC1 phosphorylation by phosphorylated EGFR (Gallus gallus)
ADP [cytosol]
Signaling by ERBB2 (Gallus gallus)
Downregulation of ERBB2 signaling (Gallus gallus)
Downregulation of ERBB2:ERBB3 signaling (Gallus gallus)
Phosphorylation of USP8 by P-AKT (Gallus gallus)
ADP [cytosol]
PI3K events in ERBB2 signaling (Gallus gallus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Gallus gallus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Gallus gallus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Gallus gallus)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Gallus gallus)
Activated PKC phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Gallus gallus)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Gallus gallus)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Gallus gallus)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Gallus gallus)
ADP [cytosol]
Signaling by ERBB4 (Gallus gallus)
PI3K events in ERBB4 signaling (Gallus gallus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Gallus gallus)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Gallus gallus)
Phosphorylation of SHC1 by ERBB4 homodimers (Gallus gallus)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)
ADP [cytosol]
Signaling by FGFR (Gallus gallus)
Signaling by FGFR1 (Gallus gallus)
Downstream signaling of activated FGFR1 (Gallus gallus)
FRS-mediated FGFR1 signaling (Gallus gallus)
Activated FGFR1 phosphorylates FRS2 (Gallus gallus)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Gallus gallus)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Gallus gallus)
ADP [cytosol]
PI-3K cascade:FGFR1 (Gallus gallus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Gallus gallus)
Activated FGFR1 phosphorylates PLCG1 (Gallus gallus)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Gallus gallus)
Activated FGFR1 phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
FGFR1 ligand binding and activation (Gallus gallus)
FGFR1b ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR1b (Gallus gallus)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Gallus gallus)
ADP [cytosol]
FGFR1c ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR1c (Gallus gallus)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Gallus gallus)
ADP [cytosol]
Signaling by FGFR2 (Gallus gallus)
Downstream signaling of activated FGFR2 (Gallus gallus)
FRS-mediated FGFR2 signaling (Gallus gallus)
Activated FGFR2 phosphorylates FRS2 (Gallus gallus)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Gallus gallus)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Gallus gallus)
ADP [cytosol]
PI-3K cascade:FGFR2 (Gallus gallus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Gallus gallus)
Activated FGFR2 phosphorylates PLCG1 (Gallus gallus)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Gallus gallus)
Activated FGFR2 phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
FGFR2 ligand binding and activation (Gallus gallus)
FGFR2b ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR2b (Gallus gallus)
ADP [cytosol]
FGFR2c ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR2c (Gallus gallus)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Gallus gallus)
ADP [cytosol]
Signaling by FGFR3 (Gallus gallus)
Downstream signaling of activated FGFR3 (Gallus gallus)
FRS-mediated FGFR3 signaling (Gallus gallus)
Activated FGFR3 phosphorylates FRS2 (Gallus gallus)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Gallus gallus)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Gallus gallus)
ADP [cytosol]
PI-3K cascade:FGFR3 (Gallus gallus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Gallus gallus)
Activated FGFR3 phosphorylates PLCG1 (Gallus gallus)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Gallus gallus)
Activated FGFR3 phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
FGFR3 ligand binding and activation (Gallus gallus)
FGFR3b ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR3b (Gallus gallus)
ADP [cytosol]
FGFR3c ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR3c (Gallus gallus)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Gallus gallus)
ADP [cytosol]
Signaling by FGFR4 (Gallus gallus)
Downstream signaling of activated FGFR4 (Gallus gallus)
FRS-mediated FGFR4 signaling (Gallus gallus)
Activated FGFR4 phosphorylates FRS2 (Gallus gallus)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Gallus gallus)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Gallus gallus)
ADP [cytosol]
PI-3K cascade:FGFR4 (Gallus gallus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Gallus gallus)
Activated FGFR4 phosphorylates PLCG1 (Gallus gallus)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Gallus gallus)
Activated FGFR4 phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
FGFR4 ligand binding and activation (Gallus gallus)
Autocatalytic phosphorylation of FGFR4 (Gallus gallus)
ADP [cytosol]
betaKlotho-mediated ligand binding (Gallus gallus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Gallus gallus)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Gallus gallus)
ADP [cytosol]
Signaling by Insulin receptor (Gallus gallus)
Autophosphorylation of insulin receptor (Gallus gallus)
ADP [cytosol]
Insulin receptor signalling cascade (Gallus gallus)
IRS activation (Gallus gallus)
Phosphorylation of IRS (Gallus gallus)
ADP [cytosol]
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of SHC1 (Gallus gallus)
ADP [cytosol]
Signaling by LTK (Gallus gallus)
Active LTK phosphorylates IRS1 (Gallus gallus)
ADP [cytosol]
Active LTK receptor phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
Autophosphorylation of LTK dimer:ALKAL1,2 (Gallus gallus)
ADP [cytosol]
Signaling by MET (Gallus gallus)
MET Receptor Activation (Gallus gallus)
MET dimers autophosphorylate (Gallus gallus)
ADP [cytosol]
MET activates PI3K/AKT signaling (Gallus gallus)
MET bound PI3K generates PIP3 (Gallus gallus)
ADP [cytosol]
MET phosphorylates GAB1 (Gallus gallus)
ADP [cytosol]
MET activates RAS signaling (Gallus gallus)
MET phosphorylates SHC1-2 (Gallus gallus)
ADP [cytosol]
MET activates STAT3 (Gallus gallus)
MET phosphorylates STAT3 (Gallus gallus)
ADP [cytosol]
MET promotes cell motility (Gallus gallus)
MET activates PTK2 signaling (Gallus gallus)
MET phosphorylates PTK2 (Gallus gallus)
ADP [cytosol]
PTK2 autophosphorylates (Gallus gallus)
ADP [cytosol]
SRC phosphorylates PTK2 (Gallus gallus)
ADP [cytosol]
Negative regulation of MET activity (Gallus gallus)
MET phosphorylates CBL (Gallus gallus)
ADP [cytosol]
Signaling by MST1 (Gallus gallus)
MST1R autophosphorylates (Gallus gallus)
ADP [cytosol]
Signaling by NTRKs (Gallus gallus)
Signaling by NTRK1 (TRKA) (Gallus gallus)
PI3K/AKT activation (Gallus gallus)
PI3K produces PIP3 and other phosphatidyl inositides (Gallus gallus)
ADP [cytosol]
Signalling to ERKs (Gallus gallus)
Prolonged ERK activation events (Gallus gallus)
ARMS-mediated activation (Gallus gallus)
ARMS is phosphorylated by active TrkA receptor (Gallus gallus)
ADP [cytosol]
Frs2-mediated activation (Gallus gallus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Gallus gallus)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Gallus gallus)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Gallus gallus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Gallus gallus)
ADP [cytosol]
Signalling to RAS (Gallus gallus)
p38MAPK events (Gallus gallus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Gallus gallus)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Gallus gallus)
Activated NTRK3 signals through PI3K (Gallus gallus)
Activated NTRK3 promotes SRC autophosphorylation (Gallus gallus)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Gallus gallus)
NTRK3 dimers trans-autophosphorylate (Gallus gallus)
ADP [cytosol]
Signaling by PDGF (Gallus gallus)
Autophosphorylation of PDGF alpha receptors (Gallus gallus)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Gallus gallus)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Gallus gallus)
ADP [cytosol]
Downstream signal transduction (Gallus gallus)
Activation of Src (Gallus gallus)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Gallus gallus)
ADP [cytosol]
Signaling by SCF-KIT (Gallus gallus)
Autophosphorylation of KIT (Gallus gallus)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Gallus gallus)
ADP [cytosol]
Phosphorylation of JAK2 (Gallus gallus)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Gallus gallus)
ADP [cytosol]
Phosphorylation of STATs (Gallus gallus)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Gallus gallus)
ADP [cytosol]
Regulation of KIT signaling (Gallus gallus)
PKC alpha interacts with and phosphorylates KIT (Gallus gallus)
ADP [cytosol]
Phosphorylation of APS (Gallus gallus)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Gallus gallus)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Gallus gallus)
IGF1,2:IGF1R autophosphorylates (Gallus gallus)
ADP [cytosol]
IGF1R signaling cascade (Gallus gallus)
IRS-related events triggered by IGF1R (Gallus gallus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Gallus gallus)
ADP [cytosol]
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
SHC-related events triggered by IGF1R (Gallus gallus)
IGF1R phosphorylates SHC1 (Gallus gallus)
ADP [cytosol]
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
AXL autophosphorylates on Y779 and Y821 (Gallus gallus)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)
ADP [cytosol]
FYN autophosphorylates (Gallus gallus)
ADP [cytosol]
FYN phosphorylates PAK2 (Gallus gallus)
ADP [cytosol]
PAK2 autophorylates (Gallus gallus)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Gallus gallus)
ADP [cytosol]
PTK2 autophosphorylates (Gallus gallus)
ADP [cytosol]
Phosphorylation of SRC-1 (Gallus gallus)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Gallus gallus)
ADP [cytosol]
SRC-1 phosphorylates SHB (Gallus gallus)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Gallus gallus)
ADP [cytosol]
Src kinases phosphorylate VAV (Gallus gallus)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
ADP [cytosol]
VEGFR2 autophosphorylates (Gallus gallus)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Gallus gallus)
PDK1 phosphorylates PKC (Gallus gallus)
ADP [cytosol]
PKC autophosphorylates (Gallus gallus)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Gallus gallus)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Gallus gallus)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Gallus gallus)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Gallus gallus)
AKT1 phosphorylates eNOS (Gallus gallus)
ADP [cytosol]
PAK1-3 autophosphorylates (Gallus gallus)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Gallus gallus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Gallus gallus)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Gallus gallus)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)
ADP [cytosol]
p38 MAPK activation by VEGFR (Gallus gallus)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Gallus gallus)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
RHOBTB3 ATPase cycle (Gallus gallus)
RHOBTB3 hydrolyzes ATP (Gallus gallus)
RHOBTB3:ADP [trans-Golgi network membrane] (Gallus gallus)
ADP [cytosol]
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate Formins (Gallus gallus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Gallus gallus)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Gallus gallus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Gallus gallus)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Gallus gallus)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Gallus gallus)
ADP [cytosol]
PKC phosphorylates NCF1 (Gallus gallus)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Gallus gallus)
ABL phosphorylates WAVEs (Gallus gallus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Gallus gallus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Gallus gallus)
Actin:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Detachment of WASP/WAVE (Gallus gallus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Gallus gallus)
Actin:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Gallus gallus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
ADP [cytosol]
RHO GTPases activate PAKs (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Gallus gallus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Gallus gallus)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Gallus gallus)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Gallus gallus)
ADP [cytosol]
RHO GTPases activate PKNs (Gallus gallus)
PDPK1 phosphorylates PKN1,2,3 (Gallus gallus)
ADP [cytosol]
Signaling by TGFB family members (Gallus gallus)
Signaling by Activin (Gallus gallus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Gallus gallus)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Gallus gallus)
ADP [cytosol]
Signaling by BMP (Gallus gallus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Gallus gallus)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Gallus gallus)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Gallus gallus)
TGF-beta receptor signaling activates SMADs (Gallus gallus)
Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Gallus gallus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Gallus gallus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Gallus gallus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Gallus gallus)
ADP [cytosol]
Signaling by WNT (Gallus gallus)
Beta-catenin independent WNT signaling (Gallus gallus)
Ca2+ pathway (Gallus gallus)
Activation of NLK (Gallus gallus)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Gallus gallus)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Gallus gallus)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Gallus gallus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Gallus gallus)
ADP [cytosol]
TCF dependent signaling in response to WNT (Gallus gallus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Gallus gallus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)
ADP [cytosol]
WNT mediated activation of DVL (Gallus gallus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Gallus gallus)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Gallus gallus)
ADP [cytosol]
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
ABC transporters in lipid homeostasis (Gallus gallus)
ABCA12 transports lipids from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Gallus gallus)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Gallus gallus)
ADP [cytosol]
ABCAs mediate lipid efflux (Gallus gallus)
ADP [cytosol]
ABCAs mediate lipid influx (Gallus gallus)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Gallus gallus)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Gallus gallus)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCA4 mediates atRAL transport (Gallus gallus)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Gallus gallus)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Gallus gallus)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Gallus gallus)
ADP [cytosol]
HCO3- transport through ion channel (Gallus gallus)
ADP [cytosol]
Mitochondrial ABC transporters (Gallus gallus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Gallus gallus)
ADP [cytosol]
The ABCC family mediates organic anion transport (Gallus gallus)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
ADP [cytosol]
Aquaporin-mediated transport (Gallus gallus)
Vasopressin regulates renal water homeostasis via Aquaporins (Gallus gallus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Gallus gallus)
ADP [cytosol]
Ion channel transport (Gallus gallus)
Ion transport by P-type ATPases (Gallus gallus)
ATP12A:ATP4B exchanges K+ for H+ (Gallus gallus)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Gallus gallus)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Gallus gallus)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Gallus gallus)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Gallus gallus)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Gallus gallus)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Gallus gallus)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Gallus gallus)
ADP [cytosol]
Stimuli-sensing channels (Gallus gallus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Gallus gallus)
ADP [cytosol]
Iron uptake and transport (Gallus gallus)
Transferrin endocytosis and recycling (Gallus gallus)
Acidification of Tf:TfR1 containing endosome (Gallus gallus)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Gallus gallus)
Plasma lipoprotein assembly (Gallus gallus)
HDL assembly (Gallus gallus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Gallus gallus)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Gallus gallus)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Gallus gallus)
ADP [cytosol]
Plasma lipoprotein remodeling (Gallus gallus)
HDL remodeling (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
ADP [cytosol]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Gallus gallus)
ADP [cytosol]
Vesicle-mediated transport (Gallus gallus)
Membrane Trafficking (Gallus gallus)
Clathrin-mediated endocytosis (Gallus gallus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Gallus gallus)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Gallus gallus)
clathrin:HSPA8:ADP [cytosol] (Gallus gallus)
HSP70:ADP [cytosol] (Gallus gallus)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Gallus gallus)
ADP [cytosol]
ER to Golgi Anterograde Transport (Gallus gallus)
COPI-mediated anterograde transport (Gallus gallus)
GBF1 stimulates ARF nucleotide exchange (Gallus gallus)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Gallus gallus)
ESCRT Disassembly (Gallus gallus)
ADP [cytosol]
Gap junction trafficking and regulation (Gallus gallus)
Regulation of gap junction activity (Gallus gallus)
Phosphorylation of Cx43 by c-src (Gallus gallus)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Gallus gallus)
Golgi-to-ER retrograde transport (Gallus gallus)
COPI-independent Golgi-to-ER retrograde traffic (Gallus gallus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Gallus gallus)
ADP [cytosol]
Intra-Golgi traffic (Gallus gallus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Gallus gallus)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Gallus gallus)
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Gallus gallus)
RHOBTB3:ADP [trans-Golgi network membrane] (Gallus gallus)
ADP [cytosol]
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Gallus gallus)
ADP [cytosol]
Rab regulation of trafficking (Gallus gallus)
RAB GEFs exchange GTP for GDP on RABs (Gallus gallus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Gallus gallus)
ADP [cytosol]
p-ULK1 phosphorylates DENND3 (Gallus gallus)
ADP [cytosol]
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
AMPK (complex) phosphorylates ULK1 (complex) (Homo sapiens)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Homo sapiens)
ADP [cytosol]
Selective autophagy (Homo sapiens)
Lipophagy (Homo sapiens)
PRKAA2 phosphorylates PLINs (Homo sapiens)
ADP [cytosol]
Mitophagy (Homo sapiens)
Receptor Mediated Mitophagy (Homo sapiens)
FUNDC1 is phosphorylated by CK2 (Homo sapiens)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Homo sapiens)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Homo sapiens)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Homo sapiens)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Homo sapiens)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Homo sapiens)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
ADP [cytosol]
Cell Cycle (Homo sapiens)
Cell Cycle Checkpoints (Homo sapiens)
G2/M Checkpoints (Homo sapiens)
G2/M DNA replication checkpoint (Homo sapiens)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Homo sapiens)
ADP [cytosol]
Cell Cycle, Mitotic (Homo sapiens)
M Phase (Homo sapiens)
Mitotic Metaphase and Anaphase (Homo sapiens)
Mitotic Anaphase (Homo sapiens)
Nuclear Envelope (NE) Reassembly (Homo sapiens)
Initiation of Nuclear Envelope (NE) Reformation (Homo sapiens)
CDK1 phosphorylates LBR (Homo sapiens)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Homo sapiens)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Homo sapiens)
ADP [cytosol]
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
ADP [cytosol]
Mitotic Prometaphase (Homo sapiens)
Condensation of Prometaphase Chromosomes (Homo sapiens)
CDK1 phosphorylates condensin I (Homo sapiens)
ADP [cytosol]
CK2 phosphorylates condensin I subunits (Homo sapiens)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Homo sapiens)
NEK6 and NEK7 phosphorylate EML4 (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates NUDC (Homo sapiens)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Homo sapiens)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Homo sapiens)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Homo sapiens)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Homo sapiens)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Homo sapiens)
ADP [cytosol]
Mitotic Prophase (Homo sapiens)
Golgi Cisternae Pericentriolar Stack Reorganization (Homo sapiens)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB (Homo sapiens)
ADP [cytosol]
Nuclear Envelope Breakdown (Homo sapiens)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Homo sapiens)
CDK1:CCNB phosphorylates NEK9 (Homo sapiens)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Homo sapiens)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Homo sapiens)
CDK1 phosphorylates NUP98 (Homo sapiens)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Homo sapiens)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Homo sapiens)
G1 Phase (Homo sapiens)
Cyclin D associated events in G1 (Homo sapiens)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Homo sapiens)
ADP [cytosol]
G1/S Transition (Homo sapiens)
Cyclin E associated events during G1/S transition (Homo sapiens)
AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
PTK6 phosphorylates CDKN1B (Homo sapiens)
ADP [cytosol]
Mitotic G2-G2/M phases (Homo sapiens)
G2/M Transition (Homo sapiens)
AURKA Activation by TPX2 (Homo sapiens)
TPX2 promotes AURKA autophosphorylation (Homo sapiens)
ADP [cytosol]
Centrosome maturation (Homo sapiens)
Loss of proteins required for interphase microtubule organization from the centrosome (Homo sapiens)
Loss of Nlp from mitotic centrosomes (Homo sapiens)
Plk1-mediated phosphorylation of Nlp (Homo sapiens)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Homo sapiens)
Myt-1 mediated phosphorylation of Cyclin A:Cdc2 (Homo sapiens)
ADP [cytosol]
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Homo sapiens)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Homo sapiens)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Homo sapiens)
AURKA phosphorylates PHLDA1 (Homo sapiens)
ADP [cytosol]
Polo-like kinase mediated events (Homo sapiens)
Activation of Cdc25C (Homo sapiens)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Homo sapiens)
AJUBA facilitates AURKA autophosphorylation (Homo sapiens)
ADP [cytosol]
AURKA phosphorylates PLK1 (Homo sapiens)
ADP [cytosol]
CDK1 phosphorylates BORA (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates BORA (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates OPTN (Homo sapiens)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Homo sapiens)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Homo sapiens)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Homo sapiens)
ADP [cytosol]
S Phase (Homo sapiens)
Cyclin A:Cdk2-associated events at S phase entry (Homo sapiens)
AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Homo sapiens)
PTK6 phosphorylates CDKN1B (Homo sapiens)
ADP [cytosol]
Cell-Cell communication (Homo sapiens)
Nephrin family interactions (Homo sapiens)
Phosphorylation of nephrin by FYN (Homo sapiens)
ADP [cytosol]
Signal regulatory protein family interactions (Homo sapiens)
Phosphorylation of ITIM motif in SIRP alpha (Homo sapiens)
ADP [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular Senescence (Homo sapiens)
Oxidative Stress Induced Senescence (Homo sapiens)
MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1) (Homo sapiens)
ADP [cytosol]
MAP3K5 phosphorylates MKK3 and MKK6 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
PTK6 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
Detoxification of Reactive Oxygen Species (Homo sapiens)
ATP7A transfers Cu from ATOX1 to SOD3 (Homo sapiens)
ADP [cytosol]
KEAP1-NFE2L2 pathway (Homo sapiens)
CK2 phosphorylates NFE2L2 (Homo sapiens)
ADP [cytosol]
EIF2AK3 phosphorylates NFE2L2 (Homo sapiens)
ADP [cytosol]
Nuclear events mediated by NFE2L2 (Homo sapiens)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Homo sapiens)
SRXN1 reduces hyperoxidized PRDX1 dimer (Homo sapiens)
ADP [cytosol]
PKC phosphorylates NFE2L2 (Homo sapiens)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Homo sapiens)
ADP [cytosol]
SQSTM1 oligomer is phosphorylated (Homo sapiens)
ADP [cytosol]
Cellular response to heat stress (Homo sapiens)
Regulation of HSF1-mediated heat shock response (Homo sapiens)
Constitutive phosphorylation by pERK1/2 (Homo sapiens)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Homo sapiens)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Homo sapiens)
ADP [cytosol]
HSP70s:ADP [cytosol] (Homo sapiens)
HSP13:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP14:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1B:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA2:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA4:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA5:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA6:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA7:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA8:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA9:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Homo sapiens)
HSP70s:ADP [cytosol] (Homo sapiens)
HSP13:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP14:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1B:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA2:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA4:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA5:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA6:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA7:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA8:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSPA9:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Homo sapiens)
ADP [cytosol]
Cellular response to starvation (Homo sapiens)
Response of EIF2AK4 (GCN2) to amino acid deficiency (Homo sapiens)
EIF2AK4 (GCN2) dimer autophosphorylates (Homo sapiens)
ADP [cytosol]
p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 (Homo sapiens)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Homo sapiens)
ATP binding to HSP90 triggers conformation change (Homo sapiens)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
ATP hydrolysis by HSP70 (Homo sapiens)
HSP40:HSP70:ADP:nascent protein [cytosol] (Homo sapiens)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Homo sapiens)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Homo sapiens)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Homo sapiens)
HSP40:HSP70:ADP:nascent protein [cytosol] (Homo sapiens)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Homo sapiens)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Homo sapiens)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Response of EIF2AK1 (HRI) to heme deficiency (Homo sapiens)
p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Homo sapiens)
ADP [cytosol]
p-T-EIF2AK1:ferriheme dimer autophosphorylates (Homo sapiens)
ADP [cytosol]
Unfolded Protein Response (UPR) (Homo sapiens)
IRE1alpha activates chaperones (Homo sapiens)
IRE1 dimer autophosphorylates (Homo sapiens)
ADP [cytosol]
Phosphorylated IRE1 dimer binds ADP (Homo sapiens)
ADP [cytosol]
PERK regulates gene expression (Homo sapiens)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Homo sapiens)
ADP [cytosol]
Circadian Clock (Homo sapiens)
CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)
ADP [cytosol]
DNA Replication (Homo sapiens)
DNA Replication Pre-Initiation (Homo sapiens)
Assembly of the pre-replicative complex (Homo sapiens)
Assembly of the ORC complex at the origin of replication (Homo sapiens)
ORC6 is phosphorylated on T195 (Homo sapiens)
ADP [cytosol]
Developmental Biology (Homo sapiens)
MITF-M-regulated melanocyte development (Homo sapiens)
MITF-M-dependent gene expression (Homo sapiens)
Regulation of MITF-M-dependent genes involved in pigmentation (Homo sapiens)
p-AKT2 phosphorylates Myosin 5A (Homo sapiens)
ADP [cytosol]
Transcriptional and post-translational regulation of MITF-M expression and activity (Homo sapiens)
MAPK-dependent phosphorylation of KARS (Homo sapiens)
ADP [cytosol]
Myogenesis (Homo sapiens)
Activation of p38 alpha/beta MAPK (Homo sapiens)
ADP [cytosol]
Nervous system development (Homo sapiens)
Axon guidance (Homo sapiens)
EPH-Ephrin signaling (Homo sapiens)
EPH receptors autophosphorylate (Homo sapiens)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Homo sapiens)
SFKs phosphorylate VAV2,3 (Homo sapiens)
ADP [cytosol]
EPHA-mediated growth cone collapse (Homo sapiens)
Activated ROCK phosphorylates MRLCs (Homo sapiens)
ADP [cytosol]
SFKs phosphorylate NGEF (Homo sapiens)
ADP [cytosol]
EPHB-mediated forward signaling (Homo sapiens)
EPHB phosphorylates TIAM1 (Homo sapiens)
ADP [cytosol]
FYN phosphorylates NMDAR2B (Homo sapiens)
ADP [cytosol]
LIMK phosphorylates CFL1, inactivating it (Homo sapiens)
ADP [cytosol]
PAK1 autophosphorylates (Homo sapiens)
ADP [cytosol]
PTK2 autophosphorylates at Y397 (Homo sapiens)
ADP [cytosol]
ROCK phosphorylates LIMK1,2 (Homo sapiens)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Homo sapiens)
ADP [cytosol]
Ephrin signaling (Homo sapiens)
PAKs autophosphorylate (Homo sapiens)
ADP [cytosol]
PAKs phosphorylate MLC (Homo sapiens)
ADP [cytosol]
SFKs phosphorylate EFNBs (Homo sapiens)
ADP [cytosol]
SFKs phosphorylate GIT1 (Homo sapiens)
ADP [cytosol]
L1CAM interactions (Homo sapiens)
CHL1 interactions (Homo sapiens)
CHL1 interacts with HSP7C (Homo sapiens)
ADP [cytosol]
CHL1:HSP7C [plasma membrane] (Homo sapiens)
ADP [cytosol]
Interaction between L1 and Ankyrins (Homo sapiens)
Phosphorylation of Y1229 in L1 (Homo sapiens)
ADP [cytosol]
Neurofascin interactions (Homo sapiens)
Phosphorylation of Neurofascin (Homo sapiens)
ADP [cytosol]
Phosphorylation of L1 by EPHB2 (Homo sapiens)
ADP [cytosol]
Recycling pathway of L1 (Homo sapiens)
Phosphorylation of L1 by ERK (Homo sapiens)
ADP [cytosol]
Phosphorylation of L1 by SRC (Homo sapiens)
ADP [cytosol]
Phosphorylation of L1 by p90rsk (Homo sapiens)
ADP [cytosol]
Signal transduction by L1 (Homo sapiens)
Interaction of PAK1 with Rac1-GTP (Homo sapiens)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Homo sapiens)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of L1 by CK-II (Homo sapiens)
ADP [cytosol]
Phosphorylation of VAV2 (Homo sapiens)
ADP [cytosol]
NCAM signaling for neurite out-growth (Homo sapiens)
Autophosphorylation of NCAM1 bound Fyn (Homo sapiens)
ADP [cytosol]
Phosphorylation of FAK by Src kinase (Homo sapiens)
ADP [cytosol]
Recruitment of FAK to NCAM1:Fyn in lipid rafts (Homo sapiens)
ADP [cytosol]
Netrin-1 signaling (Homo sapiens)
DCC mediated attractive signaling (Homo sapiens)
Phosphorylation of DCC by Fyn (Homo sapiens)
ADP [cytosol]
Phosphorylation of FADK1 (Homo sapiens)
ADP [cytosol]
Netrin mediated repulsion signals (Homo sapiens)
Phosphorylation of Unc5C (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Homo sapiens)
ADP [cytosol]
Role of second messengers in netrin-1 signaling (Homo sapiens)
Phosphorylation of PLCgamma by Netrin-1 (Homo sapiens)
ADP [cytosol]
RET signaling (Homo sapiens)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Homo sapiens)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Homo sapiens)
ADP [cytosol]
RET tyrosine phosphorylation (Homo sapiens)
ADP [cytosol]
Reelin signalling pathway (Homo sapiens)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Homo sapiens)
ADP [cytosol]
Semaphorin interactions (Homo sapiens)
CRMPs in Sema3A signaling (Homo sapiens)
Phosphorylation of CRMPs by Cdk5 (Homo sapiens)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Homo sapiens)
ADP [cytosol]
Recruitment and activation of Cdk5 (Homo sapiens)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)
ADP [cytosol]
SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion (Homo sapiens)
Phosphorylation of Plexin-A (Homo sapiens)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Homo sapiens)
Autophosphorylation of PAK (Homo sapiens)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Homo sapiens)
ADP [cytosol]
Phosphorylation of cofilin by LIMK-1 (Homo sapiens)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Homo sapiens)
ADP [cytosol]
Sema4D in semaphorin signaling (Homo sapiens)
Sema4D induced cell migration and growth-cone collapse (Homo sapiens)
LIM kinase phosphorylation by ROCK (Homo sapiens)
ADP [cytosol]
Myosin regulatory light chain phosphorylation by ROCK (Homo sapiens)
ADP [cytosol]
SEMA4D interacts with Plexin-B1:ErbB2 (Homo sapiens)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Homo sapiens)
SEMA4D interacts with Plexin-B1:Met (Homo sapiens)
ADP [cytosol]
Signaling by ROBO receptors (Homo sapiens)
ROBO receptors bind AKAP5 (Homo sapiens)
PKC phosphorylates ROBO3.1 (Homo sapiens)
ADP [cytosol]
Regulation of commissural axon pathfinding by SLIT and ROBO (Homo sapiens)
SRC phosphorylates ROBO3.1 in response to NTN1 (Homo sapiens)
ADP [cytosol]
Role of ABL in ROBO-SLIT signaling (Homo sapiens)
Phosphorylation of ROBO1 by ABL kinase (Homo sapiens)
ADP [cytosol]
Signaling by NODAL (Homo sapiens)
Phosphorylation of R-SMAD2/3 by NODAL receptor (Homo sapiens)
ADP [cytosol]
Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL (Homo sapiens)
ADP [cytosol]
Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL (Homo sapiens)
ADP [cytosol]
Disease (Homo sapiens)
Diseases of programmed cell death (Homo sapiens)
Defective Intrinsic Pathway for Apoptosis (Homo sapiens)
Neurodegenerative Diseases (Homo sapiens)
Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models (Homo sapiens)
CDK5:p25 phosphorylates FOXO3 (Homo sapiens)
ADP [cytosol]
CDK5:p25 phosphorylates GOLGA2 (Homo sapiens)
ADP [cytosol]
CDK5:p25 phosphorylates PRDX1 (Homo sapiens)
ADP [cytosol]
CDK5:p25 phosphorylates PRDX2 (Homo sapiens)
ADP [cytosol]
p25-bound CDK5 phosphorylates CDC25B (Homo sapiens)
ADP [cytosol]
p25-bound CDK5 phosphorylates CDC25C (Homo sapiens)
ADP [cytosol]
Diseases of signal transduction by growth factor receptors and second messengers (Homo sapiens)
FLT3 signaling in disease (Homo sapiens)
Signaling by FLT3 ITD and TKD mutants (Homo sapiens)
Constitutive phosphorylation of FLT3 mutants (Homo sapiens)
ADP [cytosol]
FLT3 mutants phosphorylate GAB2 (Homo sapiens)
ADP [cytosol]
STAT5 activation downstream of FLT3 ITD mutants (Homo sapiens)
FLT3 ITD mutants phosphorylate STAT5 (Homo sapiens)
ADP [cytosol]
Signaling by FLT3 fusion proteins (Homo sapiens)
FLT3 fusion dimers autophosphorylate (Homo sapiens)
ADP [cytosol]
FLT3 fusions phosphorylate GAB2 (Homo sapiens)
ADP [cytosol]
Hh mutants abrogate ligand secretion (Homo sapiens)
Hh mutants are degraded by ERAD (Homo sapiens)
Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)
ADP [cytosol]
Oncogenic MAPK signaling (Homo sapiens)
Paradoxical activation of RAF signaling by kinase inactive BRAF (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants (Homo sapiens)
ADP [cytosol]
RAF is paradoxically phosphorylated downstream of kinase-inactive RAF (Homo sapiens)
ADP [cytosol]
RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
ADP [cytosol]
Signaling by BRAF and RAF1 fusions (Homo sapiens)
BRAF and RAF fusion mutant dimers are phosphorylated (Homo sapiens)
ADP [cytosol]
MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers (Homo sapiens)
ADP [cytosol]
p-BRAF and RAF fusion dimers phosphorylate MAP2Ks (Homo sapiens)
ADP [cytosol]
Signaling by MAP2K mutants (Homo sapiens)
MAP2K mutants constitutively phosphorylate MAPKs (Homo sapiens)
ADP [cytosol]
Signaling by RAF1 mutants (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants (Homo sapiens)
ADP [cytosol]
Phosphorylation of RAF1 mutants (Homo sapiens)
ADP [cytosol]
RAF1 mutant complexes phosphorylate MAP2K dimer (Homo sapiens)
ADP [cytosol]
Signaling by RAS mutants (Homo sapiens)
Signaling downstream of RAS mutants (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS (Homo sapiens)
ADP [cytosol]
Mutant RAS:p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
ADP [cytosol]
RAF is phosphorylated downstream of oncogenic RAS (Homo sapiens)
ADP [cytosol]
Signaling by high-kinase activity BRAF mutants (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants (Homo sapiens)
ADP [cytosol]
High kinase activity BRAF complexes phosphorylate MAP2Ks (Homo sapiens)
ADP [cytosol]
Signaling by moderate kinase activity BRAF mutants (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants (Homo sapiens)
ADP [cytosol]
RAF is phosphorylated downstream of moderate kinase activity BRAF mutants (Homo sapiens)
ADP [cytosol]
RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
ADP [cytosol]
PI3K/AKT Signaling in Cancer (Homo sapiens)
Constitutive Signaling by AKT1 E17K in Cancer (Homo sapiens)
AKT1 E17K mutant is phosphorylated by TORC2 complex (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates BAD (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates CHUK (IKKalpha) (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates GSK3 (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates MDM2 (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates TSC2, inhibiting it (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates caspase-9 (Homo sapiens)
ADP [cytosol]
AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates AKT1 E17K mutant (Homo sapiens)
ADP [cytosol]
Constitutive Signaling by Aberrant PI3K in Cancer (Homo sapiens)
PI3K gain of function mutants phosphorylate PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Signaling by ALK in cancer (Homo sapiens)
Signaling by ALK fusions and activated point mutants (Homo sapiens)
ALK fusions phosphorylate FRS (Homo sapiens)
ADP [cytosol]
ALK fusions phosphorylate IRS1 (Homo sapiens)
ADP [cytosol]
ALK fusions phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
ALK mutants phosphorylate SHC1 (Homo sapiens)
ADP [cytosol]
ALK mutants phosphorylate STAT3 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of ALK fusions (Homo sapiens)
ADP [cytosol]
Autophosphorylation of point mutants of ALK (Homo sapiens)
ADP [cytosol]
NPM1-ALK- and PI3K-dependent MDM2 phosphorylation (Homo sapiens)
ADP [cytosol]
NPM1-ALK-dependent MAPK8,9 phosphorylation (Homo sapiens)
ADP [cytosol]
NPM1-ALK-dependent TYK2 phosphorylation (Homo sapiens)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK mutants (Homo sapiens)
ADP [cytosol]
TYK2-dependent STAT1 and STAT3 phosphorylation (Homo sapiens)
ADP [cytosol]
Signaling by EGFR in Cancer (Homo sapiens)
Signaling by EGFRvIII in Cancer (Homo sapiens)
Constitutive Signaling by EGFRvIII (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII (Homo sapiens)
ADP [cytosol]
Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant (Homo sapiens)
ADP [cytosol]
Phosphorylation of SHC1 by p-5Y-EGFRvIII (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of EGFRvIII mutant dimers (Homo sapiens)
ADP [cytosol]
Signaling by Ligand-Responsive EGFR Variants in Cancer (Homo sapiens)
Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
ADP [cytosol]
Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
ADP [cytosol]
Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
ADP [cytosol]
Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers (Homo sapiens)
ADP [cytosol]
Signaling by ERBB2 in Cancer (Homo sapiens)
Constitutive Signaling by Overexpressed ERBB2 (Homo sapiens)
ERBB2 homodimer phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 homodimer (Homo sapiens)
ADP [cytosol]
Signaling by ERBB2 ECD mutants (Homo sapiens)
Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)
ADP [cytosol]
Signaling by ERBB2 KD Mutants (Homo sapiens)
ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 (Homo sapiens)
ADP [cytosol]
Signaling by ERBB2 TMD/JMD mutants (Homo sapiens)
ERBB2 TMD/JMD heterodimers trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 (Homo sapiens)
ADP [cytosol]
Signaling by FGFR in disease (Homo sapiens)
Signaling by FGFR1 in disease (Homo sapiens)
Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Activated FGFR1 mutants and fusions phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
Activated FGFR1 mutants phosphorylate FRS2 (Homo sapiens)
ADP [cytosol]
FGFR1 mutant receptor activation (Homo sapiens)
Signaling by FGFR1 amplification mutants (Homo sapiens)
Ligand-independent phosphorylation of overexpressed FGFR1 (Homo sapiens)
ADP [cytosol]
Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)
ADP [cytosol]
Signaling by activated point mutants of FGFR1 (Homo sapiens)
Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR1c P252X mutant dimers (Homo sapiens)
ADP [cytosol]
Signaling by cytosolic FGFR1 fusion mutants (Homo sapiens)
BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. (Homo sapiens)
ADP [cytosol]
Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of BCR moiety of BCR-FGFR1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)
ADP [cytosol]
Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)
ADP [cytosol]
p-BCR-p-FGFR1 phosphorylates GAB2 (Homo sapiens)
ADP [cytosol]
Signaling by plasma membrane FGFR1 fusions (Homo sapiens)
Plasma membrane FGFR1 fusions autophosphorylate (Homo sapiens)
ADP [cytosol]
Signaling by FGFR2 in disease (Homo sapiens)
Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Activated FGFR2 mutants phosphorylate FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR2 mutants phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
FGFR2 mutant receptor activation (Homo sapiens)
Activated point mutants of FGFR2 (Homo sapiens)
Autocatalytic phosphorylation of FGFR2 ligand-independent mutants (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding (Homo sapiens)
ADP [cytosol]
Signaling by FGFR2 amplification mutants (Homo sapiens)
Autocatalytic phosphorylation of overexpressed FGFR2 variants (Homo sapiens)
ADP [cytosol]
Signaling by FGFR2 fusions (Homo sapiens)
FGFR2 fusions autophosphorylate (Homo sapiens)
ADP [cytosol]
Signaling by FGFR3 in disease (Homo sapiens)
Activated FGFR3 point and translocation mutants phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 (Homo sapiens)
ADP [cytosol]
FGFR3 mutant receptor activation (Homo sapiens)
Signaling by FGFR3 fusions in cancer (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 fusions (Homo sapiens)
ADP [cytosol]
Signaling by activated point mutants of FGFR3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR3c P250R mutant (Homo sapiens)
ADP [cytosol]
t(4;14) translocations of FGFR3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)
ADP [cytosol]
Signaling by FGFR4 in disease (Homo sapiens)
Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Activated FGFR4 mutants phosphorylate FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR4 mutants phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
FGFR4 mutant receptor activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR4 Y367C mutant (Homo sapiens)
ADP [cytosol]
Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity (Homo sapiens)
ADP [cytosol]
Signaling by KIT in disease (Homo sapiens)
Signaling by extracellular domain mutants of KIT (Homo sapiens)
Phosphorylation of extracellular domain KIT mutants (Homo sapiens)
ADP [cytosol]
Signaling by juxtamembrane domain KIT mutants (Homo sapiens)
Phosphorylation of juxtamembrane domain KIT mutants (Homo sapiens)
ADP [cytosol]
Signaling by kinase domain mutants of KIT (Homo sapiens)
Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)
ADP [cytosol]
Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants (Homo sapiens)
KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)
ADP [cytosol]
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
ADP [cytosol]
Signaling by LTK in cancer (Homo sapiens)
CLIP1-LTK fusion autophosphorylates (Homo sapiens)
ADP [cytosol]
CLIP1-LTK promotes MAPK1 and MAPK3 phosphorylation (Homo sapiens)
ADP [cytosol]
Signaling by PDGFR in disease (Homo sapiens)
Signaling by PDGFRA extracellular domain mutants (Homo sapiens)
Autophosphorylation of PDGFRA extracellular domain dimers (Homo sapiens)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers (Homo sapiens)
ADP [cytosol]
Signaling by PDGFRA transmembrane, juxtamembrane and kinase domain mutants (Homo sapiens)
Autophosphorylation of PDGFR mutant dimers (Homo sapiens)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR (Homo sapiens)
ADP [cytosol]
Signaling by cytosolic PDGFRA and PDGFRB fusion proteins (Homo sapiens)
Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins (Homo sapiens)
ADP [cytosol]
Signaling by membrane-tethered fusions of PDGFRA or PDGFRB (Homo sapiens)
Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB (Homo sapiens)
ADP [cytosol]
Disorders of transmembrane transporters (Homo sapiens)
ABC transporter disorders (Homo sapiens)
Defective CFTR causes cystic fibrosis (Homo sapiens)
Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol (Homo sapiens)
ADP [cytosol]
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Listeria monocytogenes entry into host cells (Homo sapiens)
InlA-mediated entry of Listeria monocytogenes into host cells (Homo sapiens)
SRC autophosphorylation is positively regulated by InlA-bound CDH1 (Homo sapiens)
ADP [cytosol]
SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)
ADP [cytosol]
InlB-mediated entry of Listeria monocytogenes into host cell (Homo sapiens)
InlB-activated MET phosphorylates CBL (Homo sapiens)
ADP [cytosol]
InlB:MET dimer trans-autophophorylates (Homo sapiens)
ADP [cytosol]
Parasitic Infection Pathways (Homo sapiens)
Leishmania infection (Homo sapiens)
Killing mechanisms (Homo sapiens)
WNT5:FZD7-mediated leishmania damping (Homo sapiens)
GTP-bound RAC1 contributes to MAPK8 activation (Homo sapiens)
ADP [cytosol]
Unknown kinase phosphorylates p-DVL (Homo sapiens)
ADP [cytosol]
Leishmania parasite growth and survival (Homo sapiens)
Anti-inflammatory response favouring Leishmania parasite infection (Homo sapiens)
CD163 mediating an anti-inflammatory response (Homo sapiens)
PLK2, MAPK14 phosphorylate ADAM17 (Homo sapiens)
ADP [cytosol]
FCGR3A-mediated IL10 synthesis (Homo sapiens)
Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)
ADP [cytosol]
Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)
ADP [cytosol]
Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)
ADP [cytosol]
Parasite infection (Homo sapiens)
Leishmania phagocytosis (Homo sapiens)
FCGR3A-mediated phagocytosis (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
ADP [cytosol]
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
ADP [cytosol]
Myosin-Actin filaments [cytosol] (Homo sapiens)
ADP [cytosol]
Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Homo sapiens)
ADP [cytosol]
Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)
ADP [cytosol]
p-6Y-SYK phosphorylates VAV1,2,3 (Homo sapiens)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
ADP [cytosol]
Viral Infection Pathways (Homo sapiens)
Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
Respiratory syncytial virus (RSV) genome replication, transcription and translation (Homo sapiens)
Maturation of hRSV A proteins (Homo sapiens)
CK2 phosphorylates nascent P (Homo sapiens)
ADP [cytosol]
SARS-CoV Infections (Homo sapiens)
SARS-CoV-1 Infection (Homo sapiens)
SARS-CoV-1 Genome Replication and Transcription (Homo sapiens)
Replication of the SARS-CoV-1 genome (Homo sapiens)
nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template (Homo sapiens)
ADP [cytosol]
Translation of Structural Proteins (Homo sapiens)
Maturation of nucleoprotein (Homo sapiens)
GSK3 phosphorylates Nucleoprotein (Homo sapiens)
ADP [cytosol]
SARS-CoV-2 Infection (Homo sapiens)
Early SARS-CoV-2 Infection Events (Homo sapiens)
SARS-CoV-2 Genome Replication and Transcription (Homo sapiens)
Replication of the SARS-CoV-2 genome (Homo sapiens)
nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template (Homo sapiens)
ADP [cytosol]
Late SARS-CoV-2 Infection Events (Homo sapiens)
Translation of Accessory Proteins (Homo sapiens)
Unknown kinase phosphorylates 9b (Homo sapiens)
ADP [cytosol]
Translation of Structural Proteins (Homo sapiens)
Maturation of nucleoprotein (Homo sapiens)
CSNK1A1 phosphorylates nucleoprotein (Homo sapiens)
ADP [cytosol]
GSK3 phosphorylates nucleoprotein (Homo sapiens)
ADP [cytosol]
SRPK1/2 phosphorylates nucleoprotein (Homo sapiens)
ADP [cytosol]
Unknown kinase phosphorylates nucleoprotein (Homo sapiens)
ADP [cytosol]
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 activates/modulates innate and adaptive immune responses (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT1 (Homo sapiens)
ADP [cytosol]
TBK1, IKBKE are autophosphorylated at Ser172 (Homo sapiens)
ADP [cytosol]
SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
PDPK1 phosphorylates AKT at T308 (Homo sapiens)
ADP [cytosol]
Drug ADME (Homo sapiens)
Abacavir ADME (Homo sapiens)
Abacavir metabolism (Homo sapiens)
carbovir diphosphate + ATP => carbovir triphosphate + ADP (Homo sapiens)
ADP [cytosol]
carbovir monophosphate + ATP => carbovir diphosphate + ADP (Homo sapiens)
ADP [cytosol]
Abacavir transmembrane transport (Homo sapiens)
abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)
ADP [cytosol]
Aspirin ADME (Homo sapiens)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Homo sapiens)
ADP [cytosol]
Azathioprine ADME (Homo sapiens)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Homo sapiens)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Homo sapiens)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Homo sapiens)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Homo sapiens)
ADP [cytosol]
Ciprofloxacin ADME (Homo sapiens)
ABCG2 transports Cipro from hepatic cell to extracellular space (Homo sapiens)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Homo sapiens)
ADP [cytosol]
Paracetamol ADME (Homo sapiens)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Homo sapiens)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Homo sapiens)
ADP [cytosol]
Prednisone ADME (Homo sapiens)
ABCB1 transports PREDN,PREDL out of hepatic cells (Homo sapiens)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Homo sapiens)
ADP [cytosol]
Ribavirin ADME (Homo sapiens)
ADK phosphorylates RBV (Homo sapiens)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Homo sapiens)
ADP [cytosol]
Unknown kinase phosphorylates RBV-MP (Homo sapiens)
ADP [cytosol]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
Regulation of TP53 Activity (Homo sapiens)
Regulation of TP53 Expression and Degradation (Homo sapiens)
Regulation of TP53 Degradation (Homo sapiens)
AKT phosphorylates MDM2 (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Homo sapiens)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Homo sapiens)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Homo sapiens)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Homo sapiens)
AKT phosphorylates TSC2, inhibiting it (Homo sapiens)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Homo sapiens)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Homo sapiens)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Homo sapiens)
PLK2 phosphorylates CENPJ (Homo sapiens)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Homo sapiens)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Homo sapiens)
ADP [cytosol]
Transcriptional regulation by RUNX2 (Homo sapiens)
RUNX2 regulates bone development (Homo sapiens)
RUNX2 regulates osteoblast differentiation (Homo sapiens)
SRC,YES1 phosphorylate YAP1 (Homo sapiens)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Homo sapiens)
Regulation of RUNX3 expression and activity (Homo sapiens)
SRC phosphorylates RUNX3 (Homo sapiens)
ADP [cytosol]
Hemostasis (Homo sapiens)
Cell surface interactions at the vascular wall (Homo sapiens)
PECAM1 interactions (Homo sapiens)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Homo sapiens)
ADP [cytosol]
Tie2 Signaling (Homo sapiens)
Trans-phosphorylation of Tie2 (Homo sapiens)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Homo sapiens)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Homo sapiens)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Homo sapiens)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Homo sapiens)
ADP [cytosol]
Kinesins (Homo sapiens)
Kinesins move along microtubules consuming ATP (Homo sapiens)
ADP [cytosol]
Platelet activation, signaling and aggregation (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
DAG kinase produces phosphatidic acid from DAG (Homo sapiens)
ADP [cytosol]
GPVI-mediated activation cascade (Homo sapiens)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Homo sapiens)
ADP [cytosol]
PDPK1 activates PRKCZ (Homo sapiens)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
SYK autophosphorylates (Homo sapiens)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Homo sapiens)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Homo sapiens)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Homo sapiens)
ADP [cytosol]
p-Y348-SYK phosphorylates VAV family (Homo sapiens)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Homo sapiens)
Integrin signaling (Homo sapiens)
Autophosphorylation of PTK2 at Y397 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of SRC (Homo sapiens)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Homo sapiens)
ADP [cytosol]
SYK activation by SRC (Homo sapiens)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Homo sapiens)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Homo sapiens)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Homo sapiens)
Disinhibition of SNARE formation (Homo sapiens)
Phosphorylation of Platelet Sec-1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Homo sapiens)
ADP [cytosol]
Platelet degranulation (Homo sapiens)
ABCC4 accumulation of dense granule contents (Homo sapiens)
ADP [cytosol]
Signal amplification (Homo sapiens)
ADP signalling through P2Y purinoceptor 1 (Homo sapiens)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Homo sapiens)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Homo sapiens)
ADP [cytosol]
Platelet homeostasis (Homo sapiens)
Platelet sensitization by LDL (Homo sapiens)
FGR binds and phosphorylates LRP8 (Homo sapiens)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Homo sapiens)
ADP [cytosol]
PECAM1 is phosphorylated (Homo sapiens)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Homo sapiens)
ADP [cytosol]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Homo sapiens)
Transport of Antigen peptide in to ER (Homo sapiens)
ADP [cytosol]
Antigen processing-Cross presentation (Homo sapiens)
ER-Phagosome pathway (Homo sapiens)
IKKB phosphorylates SNAP23 (Homo sapiens)
ADP [cytosol]
Translocation of antigenic peptides back to phagosomes via TAP (Homo sapiens)
ADP [cytosol]
Costimulation by the CD28 family (Homo sapiens)
CD28 co-stimulation (Homo sapiens)
CD28 dependent PI3K/Akt signaling (Homo sapiens)
AKT interacts and phosphorylates Cot (Homo sapiens)
ADP [cytosol]
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Homo sapiens)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Homo sapiens)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Homo sapiens)
ADP [cytosol]
CD28 dependent Vav1 pathway (Homo sapiens)
Activation of Vav1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of CD28 (Homo sapiens)
ADP [cytosol]
CTLA4 inhibitory signaling (Homo sapiens)
Phosphorylation of CTLA-4 (Homo sapiens)
ADP [cytosol]
HVEM induses BTLA phosphorylation (Homo sapiens)
ADP [cytosol]
PD-1 signaling (Homo sapiens)
Phosphorylation of PD-1 (Homo sapiens)
ADP [cytosol]
MHC class II antigen presentation (Homo sapiens)
Transport of antigen loaded MHC II molecules to surface (Homo sapiens)
ADP [cytosol]
Rap1 signalling (Homo sapiens)
PKA/PKG phosphorylate Rap1GAP2 (Homo sapiens)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Homo sapiens)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Homo sapiens)
BTK autophosphorylates (Homo sapiens)
ADP [cytosol]
CD19 is phosphorylated (Homo sapiens)
ADP [cytosol]
LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) (Homo sapiens)
ADP [cytosol]
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Homo sapiens)
ADP [cytosol]
Phosphorylated BTK phosphorylates PLCG2 (Homo sapiens)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Homo sapiens)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Homo sapiens)
ADP [cytosol]
p-SYK and LYN phosphorylate BTK (Homo sapiens)
ADP [cytosol]
CD22 mediated BCR regulation (Homo sapiens)
LYN phosphorylates CD22 (Homo sapiens)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Homo sapiens)
Activation of NF-kappaB in B cells (Homo sapiens)
Activated IKK phosphorylates I-kappaB (Homo sapiens)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Homo sapiens)
ADP [cytosol]
TAK1 associated with the CBM complex phosphorylates IKKbeta (Homo sapiens)
ADP [cytosol]
Activation of RAS in B cells (Homo sapiens)
RasGRP1 and RasGRP3 binds diacylglycerol and is phosphorylated (Homo sapiens)
ADP [cytosol]
TCR signaling (Homo sapiens)
Downstream TCR signaling (Homo sapiens)
Activation of IKK complex (Homo sapiens)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Homo sapiens)
ADP [cytosol]
Change of PKC theta conformation (Homo sapiens)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of Bcl10 (Homo sapiens)
ADP [cytosol]
Phosphorylation of CARMA1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of PKC theta (Homo sapiens)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Homo sapiens)
ADP [cytosol]
Generation of second messenger molecules (Homo sapiens)
Phosphorylation of PLC-gamma1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of SLP-76 (Homo sapiens)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Homo sapiens)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Homo sapiens)
Activation of Lck (Homo sapiens)
ADP [cytosol]
Inactivation of Lck by Csk (Homo sapiens)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Homo sapiens)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Homo sapiens)
Activation of ZAP-70 (Homo sapiens)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Homo sapiens)
ADP [cytosol]
Cytokine Signaling in Immune system (Homo sapiens)
FLT3 Signaling (Homo sapiens)
Active FLT3 phosphorylates CDKN1B (Homo sapiens)
ADP [cytosol]
FLT3 phosphorylates GRB10 (Homo sapiens)
ADP [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)
ADP [cytosol]
GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated (Homo sapiens)
ADP [cytosol]
Negative regulation of FLT3 (Homo sapiens)
FLT3 phosphorylates CBL (Homo sapiens)
ADP [cytosol]
STAT5 Activation (Homo sapiens)
Activator phosphorylates STAT5 (Homo sapiens)
ADP [cytosol]
Growth hormone receptor signaling (Homo sapiens)
JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)
ADP [cytosol]
JAK2 phosphorylation (Homo sapiens)
ADP [cytosol]
JAK2 phosphorylation of GHR (Homo sapiens)
ADP [cytosol]
JAK2 phosphorylation of IRS-1/2 (Homo sapiens)
ADP [cytosol]
Lyn activates ERK (Homo sapiens)
ADP [cytosol]
STAT5 tyrosine phosphorylation (Homo sapiens)
ADP [cytosol]
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
PKR-mediated signaling (Homo sapiens)
PKR dimer autophosphorylates (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates CDK1 (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates HIV tat (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates MAPT (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Homo sapiens)
ADP [cytosol]
p-PKR dimer phosphorylates eIF2-alpha (Homo sapiens)
ADP [cytosol]
Interferon alpha/beta signaling (Homo sapiens)
Activation of JAK kinases (Homo sapiens)
ADP [cytosol]
Formation of p-STAT1 homodimer (Homo sapiens)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT2 (Homo sapiens)
ADP [cytosol]
Interferon gamma signaling (Homo sapiens)
IFNG signaling activates MAPKs (Homo sapiens)
JAK1-activated RAF1 phosphorylates MAPKs (Homo sapiens)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Homo sapiens)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Homo sapiens)
ADP [cytosol]
Phosphorylation of JAK2 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Homo sapiens)
ADP [cytosol]
Transphosphorylation of JAK1 (Homo sapiens)
ADP [cytosol]
Prolactin receptor signaling (Homo sapiens)
JAK2 phosphorylation (Homo sapiens)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Homo sapiens)
ADP [cytosol]
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
ADP [cytosol]
SHP2 is phosphorylated (Homo sapiens)
ADP [cytosol]
Tyrosine phosphorylation of PRLR (Homo sapiens)
ADP [cytosol]
Signaling by CSF1 (M-CSF) in myeloid cells (Homo sapiens)
CSF1R trans-autophosphorylates on multiple tyrosine and serine residues (Homo sapiens)
ADP [cytosol]
CSF1R trans-autophosphorylates on tyrosine-561 (Homo sapiens)
ADP [cytosol]
CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 (Homo sapiens)
ADP [cytosol]
PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)
ADP [cytosol]
Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL (Homo sapiens)
ADP [cytosol]
Signaling by CSF3 (G-CSF) (Homo sapiens)
CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 (Homo sapiens)
ADP [cytosol]
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK (Homo sapiens)
ADP [cytosol]
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)
ADP [cytosol]
p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 (Homo sapiens)
ADP [cytosol]
p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 (Homo sapiens)
ADP [cytosol]
Signaling by Interleukins (Homo sapiens)
Interleukin-1 family signaling (Homo sapiens)
Interleukin-1 signaling (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
IKBA is phosphorylated by Phospho IKKB kinase (Homo sapiens)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Homo sapiens)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Homo sapiens)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Homo sapiens)
ADP [cytosol]
Interleukin-37 signaling (Homo sapiens)
STAT3 phosphorylation (Homo sapiens)
ADP [cytosol]
TBK1 phosphorylation (Homo sapiens)
ADP [cytosol]
Interleukin-38 signaling (Homo sapiens)
MAPK8 phosphorylation (Homo sapiens)
ADP [cytosol]
Interleukin-10 signaling (Homo sapiens)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Homo sapiens)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Homo sapiens)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Homo sapiens)
ADP [cytosol]
Interleukin-12 family signaling (Homo sapiens)
Interleukin-12 signaling (Homo sapiens)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Homo sapiens)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Homo sapiens)
ADP [cytosol]
STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction (Homo sapiens)
ADP [cytosol]
Interleukin-23 signaling (Homo sapiens)
IL23R in IL23:IL23 receptor complex is phosphorylated (Homo sapiens)
ADP [cytosol]
JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated (Homo sapiens)
ADP [cytosol]
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Homo sapiens)
ADP [cytosol]
Interleukin-27 signaling (Homo sapiens)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Homo sapiens)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Homo sapiens)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Homo sapiens)
ADP [cytosol]
Interleukin-35 Signalling (Homo sapiens)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Homo sapiens)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Homo sapiens)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Homo sapiens)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Homo sapiens)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Homo sapiens)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Homo sapiens)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Homo sapiens)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Homo sapiens)
ADP [cytosol]
Interleukin-17 signaling (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Interleukin-2 family signaling (Homo sapiens)
Interleukin receptor SHC signaling (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
ADP [cytosol]
Interleukin-15 signaling (Homo sapiens)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Homo sapiens)
ADP [cytosol]
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 (Homo sapiens)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Homo sapiens)
ADP [cytosol]
IL2RB and IL2RG are phosphorylated (Homo sapiens)
ADP [cytosol]
Interleukin-2 signaling (Homo sapiens)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Homo sapiens)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Homo sapiens)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Homo sapiens)
ADP [cytosol]
SYK is a substrate for JAK1 (Homo sapiens)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Homo sapiens)
ADP [cytosol]
Interleukin-21 signaling (Homo sapiens)
IL21 receptor JAK phosphorylation (Homo sapiens)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Homo sapiens)
ADP [cytosol]
Interleukin-9 signaling (Homo sapiens)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Homo sapiens)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Homo sapiens)
ADP [cytosol]
Interleukin-20 family signaling (Homo sapiens)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Homo sapiens)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Homo sapiens)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Homo sapiens)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Homo sapiens)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Homo sapiens)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Homo sapiens)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Homo sapiens)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
ADP [cytosol]
Interleukin receptor SHC signaling (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
ADP [cytosol]
JAK2 is phosphorylated, activated (Homo sapiens)
ADP [cytosol]
Regulation of signaling by CBL (Homo sapiens)
CBL is tyrosine phosphorylated (Homo sapiens)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Homo sapiens)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Homo sapiens)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Homo sapiens)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Homo sapiens)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Homo sapiens)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Homo sapiens)
ADP [cytosol]
Interleukin-6 family signaling (Homo sapiens)
Interleukin-6 signaling (Homo sapiens)
IL6ST is tyrosine phosphorylated (Homo sapiens)
ADP [cytosol]
JAK activation (Homo sapiens)
ADP [cytosol]
PTPN11 is phosphorylated (Homo sapiens)
ADP [cytosol]
Serine phosphorylation of STATs (Homo sapiens)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Homo sapiens)
ADP [cytosol]
Interleukin-7 signaling (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Homo sapiens)
ADP [cytosol]
IL7R is phosphorylated on Y499 (Homo sapiens)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Homo sapiens)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Homo sapiens)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Homo sapiens)
NIK-->noncanonical NF-kB signaling (Homo sapiens)
Active NIK phosphorylates IKKA dimer (Homo sapiens)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)
ADP [cytosol]
NIK autophosphorylates on T559 (Homo sapiens)
ADP [cytosol]
Innate Immune System (Homo sapiens)
Alpha-protein kinase 1 signaling pathway (Homo sapiens)
ALPK1 phosphorylates TIFA (Homo sapiens)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Homo sapiens)
ADP [cytosol]
Antimicrobial peptides (Homo sapiens)
Ion influx/efflux at host-pathogen interface (Homo sapiens)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Homo sapiens)
ADP [cytosol]
C-type lectin receptors (CLRs) (Homo sapiens)
CD209 (DC-SIGN) signaling (Homo sapiens)
PAK phosphorylates p21 RAF1 on S338 (Homo sapiens)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Homo sapiens)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Homo sapiens)
1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG (Homo sapiens)
ADP [cytosol]
Dectin-1 mediated noncanonical NF-kB signaling (Homo sapiens)
Active NIK phosphorylates IKKA dimer (Homo sapiens)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Homo sapiens)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Homo sapiens)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Homo sapiens)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Homo sapiens)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Homo sapiens)
ADP [cytosol]
Dectin-2 family (Homo sapiens)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Homo sapiens)
ADP [cytosol]
SYK autophosphorylates (Homo sapiens)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Homo sapiens)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Homo sapiens)
LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production (Homo sapiens)
Phosphorylation of beta-catenin at Ser552 (Homo sapiens)
ADP [cytosol]
STING mediated induction of host immune responses (Homo sapiens)
IRF3-mediated induction of type I IFN (Homo sapiens)
IRF3 is phosphorylated by TBK1 (Homo sapiens)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Homo sapiens)
ADP [cytosol]
STAT6-mediated induction of chemokines (Homo sapiens)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Homo sapiens)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Homo sapiens)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Homo sapiens)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Homo sapiens)
IRF3 mediated activation of type 1 IFN (Homo sapiens)
Phosphorylation and release of IRF3 (Homo sapiens)
ADP [cytosol]
Recruitment TBK1 to dsDNA:ZBP1 followed by its activation (Homo sapiens)
ADP [cytosol]
RIP-mediated NFkB activation via ZBP1 (Homo sapiens)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
RIP1 facilitates IKK complex phosphorylation (Homo sapiens)
ADP [cytosol]
DAP12 interactions (Homo sapiens)
DAP12 signaling (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of DAP12 (Homo sapiens)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of SYK (Homo sapiens)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Homo sapiens)
TRAF3-dependent IRF activation pathway (Homo sapiens)
Phosphorylation and release of IRF3/IRF7 (Homo sapiens)
ADP [cytosol]
TBK1, IKBKE are autophosphorylated at Ser172 (Homo sapiens)
ADP [cytosol]
TRAF6 mediated IRF7 activation (Homo sapiens)
Phosphorylation and release of IRF7 (Homo sapiens)
ADP [cytosol]
TRAF6 mediated NF-kB activation (Homo sapiens)
Activation of IKK by MEKK1 (Homo sapiens)
ADP [cytosol]
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
Autophosphorylation of LYN kinase (Homo sapiens)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Homo sapiens)
Autophosphorylation of BTK/ITK (Homo sapiens)
ADP [cytosol]
Phosphorylation of PLC-gamma (Homo sapiens)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Homo sapiens)
ADP [cytosol]
FCERI mediated MAPK activation (Homo sapiens)
Autophosphorylation and activation of MEKK1 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of PAK (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of VAV (Homo sapiens)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Homo sapiens)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
FCERI mediated NF-kB activation (Homo sapiens)
Activation of TAK1 complex bound to pUb-TRAF6 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of PKC-theta (Homo sapiens)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Homo sapiens)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of PKC-theta (Homo sapiens)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Homo sapiens)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of SYK (Homo sapiens)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Homo sapiens)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Homo sapiens)
Phosphorylation of GAB2 by SYK/FYN (Homo sapiens)
ADP [cytosol]
Phosphorylation of NTAL by p-SYK/Lyn (Homo sapiens)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Homo sapiens)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Homo sapiens)
FCGR activation (Homo sapiens)
Phosphorylation of SYK by Src kinases (Homo sapiens)
ADP [cytosol]
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
ADP [cytosol]
Autophosphorylation of PAK1 (Homo sapiens)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of VAV (Homo sapiens)
ADP [cytosol]
Phosphorylation of cofilin by LIMK-1 (Homo sapiens)
ADP [cytosol]
Role of myosins in phagosome formation (Homo sapiens)
Myosin-Actin filaments [cytosol] (Homo sapiens)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Homo sapiens)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Homo sapiens)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
ADP [cytosol]
Role of phospholipids in phagocytosis (Homo sapiens)
DAG stimulates protein kinase C-delta (Homo sapiens)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of PLCG (Homo sapiens)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Homo sapiens)
NOD1/2 Signaling Pathway (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Activation of p38 MAPK (Homo sapiens)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Homo sapiens)
ADP [cytosol]
Toll-like Receptor Cascades (Homo sapiens)
Toll Like Receptor 10 (TLR10) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
ADP [cytosol]
IRAK1 recruits IKK complex (Homo sapiens)
IRAK1 phosphorylates Pellino (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Homo sapiens)
Toll Like Receptor TLR1:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
ADP [cytosol]
IRAK1 recruits IKK complex (Homo sapiens)
IRAK1 phosphorylates Pellino (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
TIRAP is phosphorylated by BTK (Homo sapiens)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Homo sapiens)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
ADP [cytosol]
IRAK1 recruits IKK complex (Homo sapiens)
IRAK1 phosphorylates Pellino (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
TIRAP is phosphorylated by BTK (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Homo sapiens)
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
TICAM1,TRAF6-dependent induction of TAK1 complex (Homo sapiens)
Activation of recruited TAK1 within the activated TLR3 complex (Homo sapiens)
ADP [cytosol]
TICAM1-dependent activation of IRF3/IRF7 (Homo sapiens)
IKKε (IKBKE) is phosphorylated within the activated TLR3 complex (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex (Homo sapiens)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR3 complex (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Homo sapiens)
MyD88-independent TLR4 cascade (Homo sapiens)
TRIF (TICAM1)-mediated TLR4 signaling (Homo sapiens)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Homo sapiens)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Homo sapiens)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Homo sapiens)
Activation of TAK1 complex bound to activated TLR4 complex (Homo sapiens)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
ADP [cytosol]
IRAK1 recruits IKK complex (Homo sapiens)
IRAK1 phosphorylates Pellino (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
TIRAP is phosphorylated by BTK (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Homo sapiens)
MyD88 cascade initiated on plasma membrane (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
ADP [cytosol]
IRAK1 recruits IKK complex (Homo sapiens)
IRAK1 phosphorylates Pellino (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Homo sapiens)
Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Homo sapiens)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Homo sapiens)
MyD88 dependent cascade initiated on endosome (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 (Homo sapiens)
ADP [cytosol]
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 (Homo sapiens)
ADP [cytosol]
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling (Homo sapiens)
Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Homo sapiens)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Homo sapiens)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Homo sapiens)
ADP [cytosol]
MAP kinase activation (Homo sapiens)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Homo sapiens)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
ADP [cytosol]
MAP3K8 is phosphorylated (Homo sapiens)
ADP [cytosol]
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
ADP [cytosol]
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
ADP [cytosol]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Pyruvate metabolism (Homo sapiens)
PKM dephosphorylates PEP to PYR (Homo sapiens)
ADP [cytosol]
Regulation of pyruvate metabolism (Homo sapiens)
NEK1 phosphorylates ME1 (Homo sapiens)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Homo sapiens)
Mitochondrial Uncoupling (Homo sapiens)
The proton buffering model (Homo sapiens)
Protons are translocated from the intermembrane space to the matrix (Homo sapiens)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
Transport and synthesis of PAPS (Homo sapiens)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)
ADP [cytosol]
Glutathione conjugation (Homo sapiens)
Glutathione synthesis and recycling (Homo sapiens)
GCL ligates L-Glu to L-Cys (Homo sapiens)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Homo sapiens)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Homo sapiens)
ADP [cytosol]
Inositol phosphate metabolism (Homo sapiens)
Synthesis of IP3 and IP4 in the cytosol (Homo sapiens)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Homo sapiens)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Homo sapiens)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Homo sapiens)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Homo sapiens)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Homo sapiens)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Homo sapiens)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Homo sapiens)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Homo sapiens)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Homo sapiens)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)
ADP [cytosol]
Integration of energy metabolism (Homo sapiens)
PKA-mediated phosphorylation of key metabolic factors (Homo sapiens)
Phosphorylation of PF2K-Pase by PKA catalytic subunit (Homo sapiens)
ADP [cytosol]
Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA (Homo sapiens)
ADP [cytosol]
Regulation of insulin secretion (Homo sapiens)
Acetylcholine regulates insulin secretion (Homo sapiens)
Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Homo sapiens)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Creatine metabolism (Homo sapiens)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Homo sapiens)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Homo sapiens)
ADP [cytosol]
Glutamate and glutamine metabolism (Homo sapiens)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Homo sapiens)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Homo sapiens)
ADP [cytosol]
Histidine catabolism (Homo sapiens)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Homo sapiens)
ADP [cytosol]
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se (Homo sapiens)
APSe is phosphorylated to PAPSe by PAPSS1,2 (Homo sapiens)
ADP [cytosol]
Selenocysteine synthesis (Homo sapiens)
Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK (Homo sapiens)
ADP [cytosol]
Metabolism of carbohydrates (Homo sapiens)
Formation of xylulose-5-phosphate (Homo sapiens)
XYLB phosphorylates D-xylulose (Homo sapiens)
ADP [cytosol]
Fructose metabolism (Homo sapiens)
Fructose catabolism (Homo sapiens)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Homo sapiens)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Homo sapiens)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)
ADP [cytosol]
Galactose catabolism (Homo sapiens)
GALK1 phosphorylates Gal to Gal1P (Homo sapiens)
ADP [cytosol]
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Homo sapiens)
ADP [cytosol]
Glycolysis (Homo sapiens)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Homo sapiens)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Homo sapiens)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Homo sapiens)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Homo sapiens)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Homo sapiens)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Homo sapiens)
ADP [cytosol]
Phosphorylation of PF2K-Pase by PKA catalytic subunit (Homo sapiens)
ADP [cytosol]
Glycogen metabolism (Homo sapiens)
Glycogen breakdown (glycogenolysis) (Homo sapiens)
glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP (Homo sapiens)
ADP [cytosol]
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Homo sapiens)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Homo sapiens)
ADP [cytosol]
Glycosaminoglycan metabolism (Homo sapiens)
Transport and synthesis of PAPS (Homo sapiens)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)
ADP [cytosol]
Pentose phosphate pathway (Homo sapiens)
RBKS phosphorylates ribose to R5P (Homo sapiens)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Homo sapiens)
ADP [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Arachidonic acid metabolism (Homo sapiens)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Homo sapiens)
ALOX5 is phosphorylated by MAPKAP2 (Homo sapiens)
ADP [cytosol]
Carnitine metabolism (Homo sapiens)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Homo sapiens)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Homo sapiens)
ACLY tetramer transforms CIT to Ac-CoA (Homo sapiens)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Homo sapiens)
ADP [cytosol]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
ABCB11 transports bile salts from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
ABCB11 transports bile salts from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
Cholesterol biosynthesis (Homo sapiens)
MVD decarboxylates MVA5PP to IPPP (Homo sapiens)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Homo sapiens)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Homo sapiens)
ADP [cytosol]
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Synthesis of PC (Homo sapiens)
Casein kinase II phosphorylates STARD10 (Homo sapiens)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Homo sapiens)
ADP [cytosol]
Synthesis of PE (Homo sapiens)
ETA is phosphorylated to PETA by CHK/ETNK (Homo sapiens)
ADP [cytosol]
PI Metabolism (Homo sapiens)
Synthesis of PIPs at the ER membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Homo sapiens)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Homo sapiens)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Homo sapiens)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane (Homo sapiens)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Homo sapiens)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Homo sapiens)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Homo sapiens)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Homo sapiens)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Homo sapiens)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane (Homo sapiens)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane (Homo sapiens)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Homo sapiens)
BMX phosphorylates RUFY1 (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Homo sapiens)
ADP [cytosol]
Sphingolipid metabolism (Homo sapiens)
Glycosphingolipid metabolism (Homo sapiens)
Glycosphingolipid biosynthesis (Homo sapiens)
CERK phosphorylates CERA to form C1P (Homo sapiens)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Homo sapiens)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Homo sapiens)
ADP [cytosol]
CSNK1G2 phosphorylates p-CERT1-2 (Homo sapiens)
ADP [cytosol]
PRKD1,2,3 phosphorylates CERT1-2 (Homo sapiens)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Homo sapiens)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Homo sapiens)
ADP [cytosol]
Triglyceride metabolism (Homo sapiens)
Triglyceride biosynthesis (Homo sapiens)
Conversion of Glycerol to Glycerol-3-phosphate (Homo sapiens)
ADP [cytosol]
Triglyceride catabolism (Homo sapiens)
hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP (Homo sapiens)
ADP [cytosol]
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
eNOS activation (Homo sapiens)
AKT1 phosphorylates eNOS (Homo sapiens)
ADP [cytosol]
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Homo sapiens)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Homo sapiens)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Homo sapiens)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Homo sapiens)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Homo sapiens)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Homo sapiens)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Homo sapiens)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Homo sapiens)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Homo sapiens)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Homo sapiens)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Homo sapiens)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Homo sapiens)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Homo sapiens)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Homo sapiens)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Homo sapiens)
ADP [cytosol]
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Homo sapiens)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Homo sapiens)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Homo sapiens)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Homo sapiens)
ADP [cytosol]
Pyrimidine biosynthesis (Homo sapiens)
CAD hexamer transforms L-Gln to CAP (Homo sapiens)
ADP [cytosol]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Homo sapiens)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Homo sapiens)
ADP [cytosol]
Pyrimidine catabolism (Homo sapiens)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Homo sapiens)
ADP [cytosol]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Homo sapiens)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Homo sapiens)
ADP [cytosol]
Pyrimidine salvage (Homo sapiens)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Homo sapiens)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Homo sapiens)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Homo sapiens)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Homo sapiens)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Homo sapiens)
ADP [cytosol]
Metabolism of porphyrins (Homo sapiens)
Heme biosynthesis (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
Heme degradation (Homo sapiens)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Homo sapiens)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Homo sapiens)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Homo sapiens)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Transport of RCbl within the body (Homo sapiens)
ABCC1 transports cytosolic RCbl to extracellular region (Homo sapiens)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Homo sapiens)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Homo sapiens)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Homo sapiens)
ADP [cytosol]
Metabolism of folate and pterines (Homo sapiens)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Homo sapiens)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Homo sapiens)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Homo sapiens)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Homo sapiens)
ADP [cytosol]
Nicotinate metabolism (Homo sapiens)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Homo sapiens)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Homo sapiens)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Homo sapiens)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Homo sapiens)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Homo sapiens)
ADP [cytosol]
Vitamin B1 (thiamin) metabolism (Homo sapiens)
TDPK phosphorylates ThDP to ThTP (Homo sapiens)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Homo sapiens)
RFK:Mg2+ phosphorylates RIB (Homo sapiens)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Homo sapiens)
Coenzyme A biosynthesis (Homo sapiens)
COASY phosphorylates DP-CoA (Homo sapiens)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Homo sapiens)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Homo sapiens)
ADP [cytosol]
PANK2 phosphorylates PanK (Homo sapiens)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Homo sapiens)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Homo sapiens)
2xPDKX:2xZn2+ phosphorylates PDX (Homo sapiens)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Homo sapiens)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Homo sapiens)
ADP [cytosol]
Metabolism of RNA (Homo sapiens)
Nonsense-Mediated Decay (NMD) (Homo sapiens)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Homo sapiens)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Homo sapiens)
MK2 phosphorylates BRF1 (Homo sapiens)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Homo sapiens)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Homo sapiens)
MAP kinase p38 phosphorylates KSRP (Homo sapiens)
ADP [cytosol]
Protein Kinase B (AKT) phosphorylates KSRP (Homo sapiens)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Homo sapiens)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Homo sapiens)
ADP [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
Synthesis of substrates in N-glycan biosythesis (Homo sapiens)
GDP-fucose biosynthesis (Homo sapiens)
FUK phosphorylates beta-Fuc to Fuc1P (Homo sapiens)
ADP [cytosol]
Sialic acid metabolism (Homo sapiens)
GNE phosphorylates ManNAc to ManNAc-6-P (Homo sapiens)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Homo sapiens)
MVD decarboxylates MVA5PP to IPPP (Homo sapiens)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Homo sapiens)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Homo sapiens)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Homo sapiens)
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
GBF1 stimulates ARF nucleotide exchange (Homo sapiens)
ADP [cytosol]
COPII-mediated vesicle transport (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Homo sapiens)
Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin (Homo sapiens)
ADP [cytosol]
TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin (Homo sapiens)
ADP [cytosol]
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Homo sapiens)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Homo sapiens)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
FN3K phosphorylates ketosamines (Homo sapiens)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Homo sapiens)
ADP [cytosol]
Protein folding (Homo sapiens)
Chaperonin-mediated protein folding (Homo sapiens)
Association of TriC/CCT with target proteins during biosynthesis (Homo sapiens)
Association of CCT/TriC with other substrates during biosynthesis (unknown chaperone) (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
CCT/TRiC:substrate complex [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Association of CCT/TriC with sphingosine kinase 1 (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Homo sapiens)
ATP binds G-protein beta associated TRiC/CCT (Homo sapiens)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
CK2 phosphorylates PDCL (Homo sapiens)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Homo sapiens)
GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Homo sapiens)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Homo sapiens)
GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Homo sapiens)
GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Homo sapiens)
GNB5:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Cooperation of Prefoldin and TriC/CCT in actin and tubulin folding (Homo sapiens)
Folding of actin by CCT/TriC (Homo sapiens)
Exchange of ADP for ATP in CCT/TriC:actin complex (Homo sapiens)
ADP [cytosol]
CCT/TRiC:ADP:actin [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Hydrolysis of ATP and release of folded actin from CCT/TriC (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Formation of tubulin folding intermediates by CCT/TriC (Homo sapiens)
ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)
ADP [cytosol]
CCT/TRiC:ADP:non-native tubulin [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Hydrolysis of ATP and release of tubulin folding intermediate from CCT/TriC (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Prefoldin mediated transfer of substrate to CCT/TriC (Homo sapiens)
Actin/tubulin:prefoldin complex associates with CCT/TriC (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
actin/tubulin-bound CCT/TRiC:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Surfactant metabolism (Homo sapiens)
ABCA3 transports PC, PG from ER membrane to lamellar body (Homo sapiens)
ADP [cytosol]
Translation (Homo sapiens)
Eukaryotic Translation Initiation (Homo sapiens)
Cap-dependent Translation Initiation (Homo sapiens)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Homo sapiens)
Cap-bound mRNA is activated by helicases (Homo sapiens)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Homo sapiens)
Ribosomal scanning (Homo sapiens)
ADP [cytosol]
L13a-mediated translational silencing of Ceruloplasmin expression (Homo sapiens)
INF-gamma induced phosphorylation of L13a (Homo sapiens)
ADP [cytosol]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
ADP [cytosol]
DMPK phosphorylates PLN (Homo sapiens)
ADP [cytosol]
PRKACA phosphorylates PLN (Homo sapiens)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Homo sapiens)
ADP [cytosol]
Smooth Muscle Contraction (Homo sapiens)
ATP Hydrolysis By Myosin (Homo sapiens)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Homo sapiens)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Homo sapiens)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Homo sapiens)
ADP [cytosol]
Release Of ADP From Myosin (Homo sapiens)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Homo sapiens)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Homo sapiens)
ADP [cytosol]
Striated Muscle Contraction (Homo sapiens)
ATP Hydrolysis By Myosin (Homo sapiens)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
ADP Bound Myosin Complex [cytosol] (Homo sapiens)
ADP [cytosol]
Release Of ADP From Myosin (Homo sapiens)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Homo sapiens)
ADP Bound Myosin Complex [cytosol] (Homo sapiens)
ADP [cytosol]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Assembly and cell surface presentation of NMDA receptors (Homo sapiens)
KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane (Homo sapiens)
ADP [cytosol]
Post NMDA receptor activation events (Homo sapiens)
Activation of AMPK downstream of NMDARs (Homo sapiens)
AMPK phosphorylates MAPT (Homo sapiens)
ADP [cytosol]
CAMKK2 phosphorylates AMPK (Homo sapiens)
ADP [cytosol]
Activation of RAC1 downstream of NMDARs (Homo sapiens)
CAMK1 phosphorylates ARHGEF7-1 (Homo sapiens)
ADP [cytosol]
CaMKK autophosphorylates in the cytosol (Homo sapiens)
ADP [cytosol]
CaMKKs phosphorylate CAMK1 (Homo sapiens)
ADP [cytosol]
CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling (Homo sapiens)
RSK activation (Homo sapiens)
ERKs phosphorylate RSKs (Homo sapiens)
ADP [cytosol]
RSKs autophosphorylate (Homo sapiens)
ADP [cytosol]
Long-term potentiation (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
ADP [cytosol]
CaMKII phosphorylates AMPA receptor (Homo sapiens)
ADP [cytosol]
SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Trafficking of AMPA receptors (Homo sapiens)
Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)
ADP [cytosol]
Neurotransmitter release cycle (Homo sapiens)
Acetylcholine Neurotransmitter Release Cycle (Homo sapiens)
Re-acidification of acetylcholine transport vesicles (Homo sapiens)
ADP [cytosol]
Dopamine Neurotransmitter Release Cycle (Homo sapiens)
Re-acidification of clathrin sculpted monoamine transport vesicle lumen (Homo sapiens)
ADP [cytosol]
Norepinephrine Neurotransmitter Release Cycle (Homo sapiens)
Re-acidification of clathrin sculpted monoamine transport vesicle lumen (Homo sapiens)
ADP [cytosol]
Serotonin Neurotransmitter Release Cycle (Homo sapiens)
Re-acidification of clathrin sculpted monoamine transport vesicle lumen (Homo sapiens)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Homo sapiens)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Homo sapiens)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Homo sapiens)
ADP [cytosol]
Programmed Cell Death (Homo sapiens)
Apoptosis (Homo sapiens)
Apoptotic execution phase (Homo sapiens)
Stimulation of the cell death response by PAK-2p34 (Homo sapiens)
Autophosphorylation of PAK-2p34 in the activation loop (Homo sapiens)
ADP [cytosol]
Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 (Homo sapiens)
ADP [cytosol]
Caspase activation via extrinsic apoptotic signalling pathway (Homo sapiens)
Caspase activation via Dependence Receptors in the absence of ligand (Homo sapiens)
Activation of caspase-3 (Homo sapiens)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Homo sapiens)
Activation of BH3-only proteins (Homo sapiens)
Activation of BAD and translocation to mitochondria (Homo sapiens)
AKT phosphorylates BAD (Homo sapiens)
ADP [cytosol]
Activation of BIM and translocation to mitochondria (Homo sapiens)
Phosphorylation of BIM by JNK (Homo sapiens)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Homo sapiens)
Phosphorylation of DLC2 by MAPK8 (Homo sapiens)
ADP [cytosol]
Apoptotic factor-mediated response (Homo sapiens)
Cytochrome c-mediated apoptotic response (Homo sapiens)
Activation of caspases through apoptosome-mediated cleavage (Homo sapiens)
Cleavage of Procaspase-3 by the apoptosome (Homo sapiens)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Homo sapiens)
ADP [cytosol]
Formation of apoptosome (Homo sapiens)
CYCS binds to APAF1 (Homo sapiens)
ADP [cytosol]
APAF1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Homo sapiens)
ADP [cytosol]
Regulation of the apoptosome activity (Homo sapiens)
APAF1 binds AVEN (Homo sapiens)
APAF1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
APAF1:AVEN [cytosol] (Homo sapiens)
APAF1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Homo sapiens)
ADP [cytosol]
Regulated Necrosis (Homo sapiens)
RIPK1-mediated regulated necrosis (Homo sapiens)
RIPK1 is phosphorylated (Homo sapiens)
ADP [cytosol]
RIPK3 is phosphorylated (Homo sapiens)
ADP [cytosol]
RIPK3 phosphorylates MLKL (Homo sapiens)
ADP [cytosol]
Protein localization (Homo sapiens)
Insertion of tail-anchored proteins into the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored protein:ASNA1:ADP binds WRB:CAMLG at the endoplasmic reticulum membrane (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
ASNA1:ADP dimer [cytosol] (Homo sapiens)
ASNA1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG [endoplasmic reticulum membrane] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
ASNA1:ADP dimer [cytosol] (Homo sapiens)
ASNA1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)
ADP [cytosol]
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG [endoplasmic reticulum membrane] (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
ASNA1:ADP dimer [cytosol] (Homo sapiens)
ASNA1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Tail-anchored protein:SGTA:BAG6:GET4:UBL4A:ASNA1:ATP dissociates and ASNA1 hydrolyzes ATP yielding Tail-anchored protein:ASNA1:ADP (Homo sapiens)
Tail-anchored protein:ASNA1:ADP [cytosol] (Homo sapiens)
ASNA1:ADP dimer [cytosol] (Homo sapiens)
ASNA1:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Peroxisomal protein import (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Homo sapiens)
ADP [cytosol]
PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 (Homo sapiens)
ADP [cytosol]
Sensory Perception (Homo sapiens)
Sensory processing of sound (Homo sapiens)
Sensory processing of sound by inner hair cells of the cochlea (Homo sapiens)
ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
ADP [cytosol]
ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
ADP [cytosol]
Sensory processing of sound by outer hair cells of the cochlea (Homo sapiens)
ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
ADP [cytosol]
Visual phototransduction (Homo sapiens)
The canonical retinoid cycle in rods (twilight vision) (Homo sapiens)
ABCA4 mediates atRAL transport (Homo sapiens)
ADP [cytosol]
ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol (Homo sapiens)
ADP [cytosol]
The phototransduction cascade (Homo sapiens)
Inactivation, recovery and regulation of the phototransduction cascade (Homo sapiens)
GRK1,4,7 phosphorylate MII to p-MII (Homo sapiens)
ADP [cytosol]
PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP (Homo sapiens)
ADP [cytosol]
Signal Transduction (Homo sapiens)
Death Receptor Signaling (Homo sapiens)
TNF signaling (Homo sapiens)
Regulation of TNFR1 signaling (Homo sapiens)
CHUK, IKBKB phosphorylate CYLD at S418 (Homo sapiens)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Homo sapiens)
ADP [cytosol]
MAPKAPK2 phosphorylates RIPK1 at S320 (Homo sapiens)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Homo sapiens)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Homo sapiens)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Homo sapiens)
Cell death signalling via NRAGE, NRIF and NADE (Homo sapiens)
NRAGE signals death through JNK (Homo sapiens)
GTP-bound RAC contributes to JNK activation (Homo sapiens)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Homo sapiens)
ADP [cytosol]
NRAGE activates JNK (Homo sapiens)
ADP [cytosol]
NRIF signals cell death from the nucleus (Homo sapiens)
NRIF and TRAF6 may activate JNK (Homo sapiens)
ADP [cytosol]
p75NTR signals via NF-kB (Homo sapiens)
NF-kB is activated and signals survival (Homo sapiens)
IKKbeta is activated (Homo sapiens)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Homo sapiens)
ADP [cytosol]
p75NTR recruits signalling complexes (Homo sapiens)
IRAK is activated (Homo sapiens)
ADP [cytosol]
Integrin signaling (Homo sapiens)
Autophosphorylation of PTK2 at Y397 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of SRC (Homo sapiens)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Homo sapiens)
ADP [cytosol]
SYK activation by SRC (Homo sapiens)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Homo sapiens)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Homo sapiens)
ADP [cytosol]
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
ADP [cytosol]
PKC phosphorylates GRK2 (Homo sapiens)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Homo sapiens)
ADP [cytosol]
PIP3 activates AKT signaling (Homo sapiens)
AKT phosphorylates targets in the cytosol (Homo sapiens)
AKT phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
ADP [cytosol]
AKT phosphorylates BAD (Homo sapiens)
ADP [cytosol]
AKT phosphorylates GSK3 (Homo sapiens)
ADP [cytosol]
AKT phosphorylates IKKalpha (Homo sapiens)
ADP [cytosol]
AKT phosphorylates MDM2 (Homo sapiens)
ADP [cytosol]
AKT phosphorylates MKRN1 (Homo sapiens)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Homo sapiens)
ADP [cytosol]
AKT phosphorylates caspase-9 (Homo sapiens)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Homo sapiens)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Homo sapiens)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Homo sapiens)
ADP [cytosol]
MAPKs phosphorylate PP2A (Homo sapiens)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Homo sapiens)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Homo sapiens)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PTEN Regulation (Homo sapiens)
Regulation of PTEN gene transcription (Homo sapiens)
mTORC1 phosphorylates MAF1 (Homo sapiens)
ADP [cytosol]
Regulation of PTEN stability and activity (Homo sapiens)
AKT phosphorylates MKRN1 (Homo sapiens)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Homo sapiens)
ADP [cytosol]
FRK phosphorylates PTEN (Homo sapiens)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Homo sapiens)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Homo sapiens)
ADP [cytosol]
MAPK family signaling cascades (Homo sapiens)
MAPK1/MAPK3 signaling (Homo sapiens)
RAF-independent MAPK1/3 activation (Homo sapiens)
MAPK1 (ERK2) activation (Homo sapiens)
MAP2K2 phosphorylates MAPK1 (Homo sapiens)
ADP [cytosol]
MAPK3 (ERK1) activation (Homo sapiens)
Inactivation of MAP2K1 by CDK1 (Homo sapiens)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Homo sapiens)
ADP [cytosol]
RAF/MAP kinase cascade (Homo sapiens)
MAP2K and MAPK activation (Homo sapiens)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Homo sapiens)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Homo sapiens)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Homo sapiens)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Homo sapiens)
ADP [cytosol]
Negative regulation of MAPK pathway (Homo sapiens)
MAPK12 phosphorylates PTPN3 (Homo sapiens)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Homo sapiens)
Activated MAPK phosphorylates RAF1 (Homo sapiens)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Homo sapiens)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Homo sapiens)
ADP [cytosol]
RAF activation (Homo sapiens)
MARK3 phosphorylates KSR1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of RAF (Homo sapiens)
ADP [cytosol]
RAS processing (Homo sapiens)
KRAS4B is phosphorylated on serine 181 (Homo sapiens)
ADP [cytosol]
MAPK6/MAPK4 signaling (Homo sapiens)
Autophosphorylation of PAK1,2,3 (Homo sapiens)
ADP [cytosol]
MAPKAPK5 phosphorylates KALRN (Homo sapiens)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Homo sapiens)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Homo sapiens)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Homo sapiens)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Homo sapiens)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Homo sapiens)
ADP [cytosol]
MTOR signalling (Homo sapiens)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Homo sapiens)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Homo sapiens)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Homo sapiens)
Phosphorylation of TSC2 by PKB (Homo sapiens)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Homo sapiens)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Homo sapiens)
ADP [cytosol]
mTORC1-mediated signalling (Homo sapiens)
Phosphorylation and activation of eIF4B by activated S6K1 (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Homo sapiens)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Homo sapiens)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)
ADP [cytosol]
Signaling by Erythropoietin (Homo sapiens)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Homo sapiens)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Homo sapiens)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Homo sapiens)
ADP [cytosol]
Erythropoietin activates Phospholipase C gamma (PLCG) (Homo sapiens)
LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 (Homo sapiens)
ADP [cytosol]
Erythropoietin activates RAS (Homo sapiens)
JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 (Homo sapiens)
ADP [cytosol]
JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 (Homo sapiens)
ADP [cytosol]
LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 (Homo sapiens)
ADP [cytosol]
Erythropoietin activates STAT5 (Homo sapiens)
JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
ADP [cytosol]
JAK2 transphosphorylates and is activated in response to Erythropoietin (Homo sapiens)
ADP [cytosol]
Phospho-JAK2 phosphorylates EPOR (Homo sapiens)
ADP [cytosol]
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Homo sapiens)
ADP [cytosol]
Opioid Signalling (Homo sapiens)
DARPP-32 events (Homo sapiens)
PKA phosphorylates DARPP-32 on Thr34 (Homo sapiens)
ADP [cytosol]
PKA phosphorylates PDE4B (Homo sapiens)
ADP [cytosol]
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
CaMK IV-mediated phosphorylation of CREB (Homo sapiens)
CaMKII autophosphorylates (Homo sapiens)
ADP [cytosol]
PKC phosphorylates GRK2 (Homo sapiens)
ADP [cytosol]
phospho-PLA2 pathway (Homo sapiens)
Phosphorylation of cPLA2 by ERK-2 (Homo sapiens)
ADP [cytosol]
G alpha (q) signalling events (Homo sapiens)
Effects of PIP2 hydrolysis (Homo sapiens)
DAG kinase produces phosphatidic acid from DAG (Homo sapiens)
ADP [cytosol]
G alpha (s) signalling events (Homo sapiens)
ADRB2 in ADRB2:GRK complex is phosphorylated (Homo sapiens)
ADP [cytosol]
G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC (Homo sapiens)
ADP [cytosol]
GPER1 signaling (Homo sapiens)
SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 (Homo sapiens)
ADP [cytosol]
G alpha (z) signalling events (Homo sapiens)
PKC phosphorylates G alpha (z) (Homo sapiens)
ADP [cytosol]
G-protein beta:gamma signalling (Homo sapiens)
G beta:gamma signalling through PI3Kgamma (Homo sapiens)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Signaling by Hedgehog (Homo sapiens)
Hedgehog 'off' state (Homo sapiens)
Degradation of GLI1 by the proteasome (Homo sapiens)
PKA phosphorylates GLI1 (Homo sapiens)
ADP [cytosol]
Degradation of GLI2 by the proteasome (Homo sapiens)
CK1 phosphorylates p-GLI2 (Homo sapiens)
ADP [cytosol]
GSK3 phosphorylates p-GLI2 (Homo sapiens)
ADP [cytosol]
PKA phosphorylates GLI2 (Homo sapiens)
ADP [cytosol]
GLI3 is processed to GLI3R by the proteasome (Homo sapiens)
CK1 phosphorylates p-GLI3 (Homo sapiens)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Homo sapiens)
ADP [cytosol]
PKA phosphorylates GLI3 (Homo sapiens)
ADP [cytosol]
Hedgehog ligand biogenesis (Homo sapiens)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Homo sapiens)
ADP [cytosol]
Signaling by Hippo (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Homo sapiens)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Homo sapiens)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Homo sapiens)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Homo sapiens)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Homo sapiens)
ADP [cytosol]
Signaling by Leptin (Homo sapiens)
JAK2 Autophosphorylates in Response to Leptin (Homo sapiens)
ADP [cytosol]
JAK2 Phosphoryates STAT3 in Response to Leptin (Homo sapiens)
ADP [cytosol]
JAK2 Phosphorylates IRS in Response to Leptin (Homo sapiens)
ADP [cytosol]
JAK2 Phosphorylates LEPR (Homo sapiens)
ADP [cytosol]
JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin (Homo sapiens)
ADP [cytosol]
JAK2 Phosphorylates STAT5 in Response to Leptin (Homo sapiens)
ADP [cytosol]
Signaling by NOTCH (Homo sapiens)
Signaling by NOTCH3 (Homo sapiens)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Homo sapiens)
EGFR phosphorylates NOTCH3 (Homo sapiens)
ADP [cytosol]
Signaling by NOTCH4 (Homo sapiens)
Negative regulation of NOTCH4 signaling (Homo sapiens)
AKT1 phosphorylates NOTCH4 (Homo sapiens)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Homo sapiens)
Signaling by PTK6 (Homo sapiens)
ERBB2 Activates PTK6 Signaling (Homo sapiens)
ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)
ADP [cytosol]
PTK6 Activates STAT3 (Homo sapiens)
PTK6 phosphorylates STAP2 (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
PTK6 Down-Regulation (Homo sapiens)
SRMS phosphorylates PTK6 (Homo sapiens)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Homo sapiens)
PTK6 phosphorylates CDKN1B (Homo sapiens)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Homo sapiens)
PTK6 phosphorylates ARHGAP35 (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates PXN (Homo sapiens)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Homo sapiens)
PTK6 phosphorylates AKT1 (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates ARAP1 (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates CBL (Homo sapiens)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Homo sapiens)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Homo sapiens)
EGFR phosphorylates GPNMB (Homo sapiens)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Homo sapiens)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Homo sapiens)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Homo sapiens)
ADP [cytosol]
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
ESR-associated SRC autophosphorylates (Homo sapiens)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Homo sapiens)
PDPK1 activates PRKCZ (Homo sapiens)
ADP [cytosol]
PRKCZ autophosphorylates downstream of estrogen stimulation (Homo sapiens)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Homo sapiens)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by ALK (Homo sapiens)
ALK autophosphorylation (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
Active ALK phosphorylates SRC (Homo sapiens)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Homo sapiens)
ADP [cytosol]
Signaling by EGFR (Homo sapiens)
EGFR autophosphorylation (Homo sapiens)
ADP [cytosol]
EGFR downregulation (Homo sapiens)
EGFR phosphorylates EPS15 (Homo sapiens)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Homo sapiens)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Homo sapiens)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Homo sapiens)
EGFR activates PLC-gamma1 by phosphorylation (Homo sapiens)
ADP [cytosol]
GAB1 signalosome (Homo sapiens)
GAB1 phosphorylation by EGFR kinase (Homo sapiens)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Homo sapiens)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Homo sapiens)
ADP [cytosol]
SHC1 events in EGFR signaling (Homo sapiens)
SHC1 phosphorylation by phosphorylated EGFR (Homo sapiens)
ADP [cytosol]
Signaling by ERBB2 (Homo sapiens)
Downregulation of ERBB2 signaling (Homo sapiens)
Downregulation of ERBB2:ERBB3 signaling (Homo sapiens)
Phosphorylation of USP8 by P-AKT (Homo sapiens)
ADP [cytosol]
ERBB2 Activates PTK6 Signaling (Homo sapiens)
ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)
ADP [cytosol]
PI3K events in ERBB2 signaling (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Homo sapiens)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Homo sapiens)
ADP [cytosol]
PLCG1 events in ERBB2 signaling (Homo sapiens)
PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Homo sapiens)
Activated PKC phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Homo sapiens)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)
ADP [cytosol]
Signaling by ERBB4 (Homo sapiens)
PI3K events in ERBB4 signaling (Homo sapiens)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Homo sapiens)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Homo sapiens)
Phosphorylation of SHC1 by ERBB4 homodimers (Homo sapiens)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Homo sapiens)
ADP [cytosol]
Signaling by FGFR (Homo sapiens)
Signaling by FGFR1 (Homo sapiens)
Downstream signaling of activated FGFR1 (Homo sapiens)
FRS-mediated FGFR1 signaling (Homo sapiens)
Activated FGFR1 phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Homo sapiens)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Homo sapiens)
ADP [cytosol]
PI-3K cascade:FGFR1 (Homo sapiens)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Homo sapiens)
Activated FGFR1 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Homo sapiens)
Activated FGFR1 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
FGFR1 ligand binding and activation (Homo sapiens)
FGFR1b ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR1b (Homo sapiens)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Homo sapiens)
ADP [cytosol]
FGFR1c ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR1c (Homo sapiens)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Homo sapiens)
ADP [cytosol]
Spry regulation of FGF signaling (Homo sapiens)
SPRY2 is phosphorylated by phosphorylated MNK1 (Homo sapiens)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)
ADP [cytosol]
Signaling by FGFR2 (Homo sapiens)
Downstream signaling of activated FGFR2 (Homo sapiens)
FRS-mediated FGFR2 signaling (Homo sapiens)
Activated FGFR2 phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Homo sapiens)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Homo sapiens)
ADP [cytosol]
PI-3K cascade:FGFR2 (Homo sapiens)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Homo sapiens)
Activated FGFR2 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Homo sapiens)
Activated FGFR2 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
FGFR2 ligand binding and activation (Homo sapiens)
FGFR2b ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR2b (Homo sapiens)
ADP [cytosol]
FGFR2c ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR2c (Homo sapiens)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Homo sapiens)
ADP [cytosol]
Spry regulation of FGF signaling (Homo sapiens)
SPRY2 is phosphorylated by phosphorylated MNK1 (Homo sapiens)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)
ADP [cytosol]
Signaling by FGFR3 (Homo sapiens)
Downstream signaling of activated FGFR3 (Homo sapiens)
FRS-mediated FGFR3 signaling (Homo sapiens)
Activated FGFR3 phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Homo sapiens)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Homo sapiens)
ADP [cytosol]
PI-3K cascade:FGFR3 (Homo sapiens)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Homo sapiens)
Activated FGFR3 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Homo sapiens)
Activated FGFR3 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
FGFR3 ligand binding and activation (Homo sapiens)
FGFR3b ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR3b (Homo sapiens)
ADP [cytosol]
FGFR3c ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR3c (Homo sapiens)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Homo sapiens)
ADP [cytosol]
Spry regulation of FGF signaling (Homo sapiens)
SPRY2 is phosphorylated by phosphorylated MNK1 (Homo sapiens)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)
ADP [cytosol]
Signaling by FGFR4 (Homo sapiens)
Downstream signaling of activated FGFR4 (Homo sapiens)
FRS-mediated FGFR4 signaling (Homo sapiens)
Activated FGFR4 phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Homo sapiens)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Homo sapiens)
ADP [cytosol]
PI-3K cascade:FGFR4 (Homo sapiens)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Homo sapiens)
Activated FGFR4 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Homo sapiens)
Activated FGFR4 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
FGFR4 ligand binding and activation (Homo sapiens)
Autocatalytic phosphorylation of FGFR4 (Homo sapiens)
ADP [cytosol]
betaKlotho-mediated ligand binding (Homo sapiens)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Homo sapiens)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Homo sapiens)
ADP [cytosol]
Spry regulation of FGF signaling (Homo sapiens)
SPRY2 is phosphorylated by phosphorylated MNK1 (Homo sapiens)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)
ADP [cytosol]
Signaling by Insulin receptor (Homo sapiens)
Autophosphorylation of insulin receptor (Homo sapiens)
ADP [cytosol]
Insulin receptor signalling cascade (Homo sapiens)
IRS activation (Homo sapiens)
Phosphorylation of IRS (Homo sapiens)
ADP [cytosol]
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
Activation of AKT2 (Homo sapiens)
PDPK1 phosphorylates AKT2 (Homo sapiens)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PKB-mediated events (Homo sapiens)
PDE3B signalling (Homo sapiens)
p-T309,S474-AKT2:PIP3 phosphorylates PDE3B (Homo sapiens)
ADP [cytosol]
Phosphorylation of SHC1 (Homo sapiens)
ADP [cytosol]
Signal attenuation (Homo sapiens)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Homo sapiens)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Homo sapiens)
ADP [cytosol]
Signaling by LTK (Homo sapiens)
Active LTK phosphorylates IRS1 (Homo sapiens)
ADP [cytosol]
Active LTK receptor phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
Autophosphorylation of LTK dimer:ALKAL1,2 (Homo sapiens)
ADP [cytosol]
Signaling by MET (Homo sapiens)
MET Receptor Activation (Homo sapiens)
MET dimers autophosphorylate (Homo sapiens)
ADP [cytosol]
MET activates PI3K/AKT signaling (Homo sapiens)
MET bound PI3K generates PIP3 (Homo sapiens)
ADP [cytosol]
MET phosphorylates GAB1 (Homo sapiens)
ADP [cytosol]
MET activates RAS signaling (Homo sapiens)
MET phosphorylates SHC1-2 (Homo sapiens)
ADP [cytosol]
MET activates STAT3 (Homo sapiens)
MET phosphorylates STAT3 (Homo sapiens)
ADP [cytosol]
MET promotes cell motility (Homo sapiens)
MET activates PTK2 signaling (Homo sapiens)
MET phosphorylates PTK2 (Homo sapiens)
ADP [cytosol]
PTK2 autophosphorylates (Homo sapiens)
ADP [cytosol]
SRC phosphorylates PTK2 (Homo sapiens)
ADP [cytosol]
Negative regulation of MET activity (Homo sapiens)
MET phosphorylates CBL (Homo sapiens)
ADP [cytosol]
Signaling by MST1 (Homo sapiens)
MST1R autophosphorylates (Homo sapiens)
ADP [cytosol]
Signaling by NTRKs (Homo sapiens)
Signaling by NTRK1 (TRKA) (Homo sapiens)
Activation of TRKA receptors (Homo sapiens)
NGF-independant TRKA activation (Homo sapiens)
NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates (Homo sapiens)
ADP [cytosol]
NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates (Homo sapiens)
ADP [cytosol]
TRKA activation by NGF (Homo sapiens)
TrkA receptor autophosphorylates (Homo sapiens)
ADP [cytosol]
PI3K/AKT activation (Homo sapiens)
PI3K produces PIP3 and other phosphatidyl inositides (Homo sapiens)
ADP [cytosol]
TRKA phosphorylates IRS (Homo sapiens)
ADP [cytosol]
PLC-gamma1 signalling (Homo sapiens)
TrkA phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
Signalling to ERK5 (Homo sapiens)
ERK5 is activated (Homo sapiens)
ADP [cytosol]
Signalling to ERKs (Homo sapiens)
Prolonged ERK activation events (Homo sapiens)
ARMS-mediated activation (Homo sapiens)
ARMS is phosphorylated by active TrkA receptor (Homo sapiens)
ADP [cytosol]
BRAF in Rap1-GTP complex:BRAF complex autophosphorylates (Homo sapiens)
ADP [cytosol]
Frs2-mediated activation (Homo sapiens)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Homo sapiens)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Homo sapiens)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Homo sapiens)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Homo sapiens)
ADP [cytosol]
Signalling to RAS (Homo sapiens)
SHC, complexed with TrkA, is tyrosine-phosphorylated (Homo sapiens)
ADP [cytosol]
p38MAPK events (Homo sapiens)
Binding and activation of MAP Kinase (Homo sapiens)
ADP [cytosol]
SRC-1 autophosphorylates (Homo sapiens)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Homo sapiens)
ADP [cytosol]
Signalling to STAT3 (Homo sapiens)
STAT3 activation (Homo sapiens)
ADP [cytosol]
Signaling by NTRK2 (TRKB) (Homo sapiens)
Activated NTRK2 signals through CDK5 (Homo sapiens)
CDK5 phosphorylates NTRK2 (Homo sapiens)
ADP [cytosol]
NTRK2 phosphorylates CDK5 (Homo sapiens)
ADP [cytosol]
NTRK2 promotes TIAM1 phosphorylation (Homo sapiens)
ADP [cytosol]
Activated NTRK2 signals through FRS2 and FRS3 (Homo sapiens)
NTRK2 phosphorylates FRS2 (Homo sapiens)
ADP [cytosol]
NTRK2 phosphorylates FRS3 (Homo sapiens)
ADP [cytosol]
Activated NTRK2 signals through FYN (Homo sapiens)
FYN-mediated phosphorylation of GRIN2B (Homo sapiens)
ADP [cytosol]
NTRK2-bound FYN autophosphorylates (Homo sapiens)
ADP [cytosol]
SRC,FYN phosphorylate NTRK2 (Homo sapiens)
ADP [cytosol]
Activated NTRK2 signals through PI3K (Homo sapiens)
NTRK2-activated PI3K generates PIP3 (Homo sapiens)
ADP [cytosol]
Activated NTRK2 signals through PLCG1 (Homo sapiens)
NTRK2 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
Activated NTRK2 signals through RAS (Homo sapiens)
NTRK2 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
BDNF activates NTRK2 (TRKB) signaling (Homo sapiens)
BDNF-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
NTF3 activates NTRK2 (TRKB) signaling (Homo sapiens)
NTF3-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
NTF4 activates NTRK2 (TRKB) signaling (Homo sapiens)
NTF4-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Homo sapiens)
Activated NTRK3 signals through PI3K (Homo sapiens)
Activated NTRK3 promotes SRC autophosphorylation (Homo sapiens)
ADP [cytosol]
Activated NTRK3 stimulates PI3K activity (Homo sapiens)
ADP [cytosol]
Activated NTRK3 signals through PLCG1 (Homo sapiens)
NTRK3 phosphorylates PLCG1 (Homo sapiens)
ADP [cytosol]
Activated NTRK3 signals through RAS (Homo sapiens)
NTRK3 phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Homo sapiens)
NTRK3 dimers trans-autophosphorylate (Homo sapiens)
ADP [cytosol]
Signaling by PDGF (Homo sapiens)
Autophosphorylation of PDGF alpha receptors (Homo sapiens)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Homo sapiens)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Homo sapiens)
ADP [cytosol]
Downstream signal transduction (Homo sapiens)
Activation of Src (Homo sapiens)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Homo sapiens)
ADP [cytosol]
Signaling by SCF-KIT (Homo sapiens)
Autophosphorylation of KIT (Homo sapiens)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Homo sapiens)
ADP [cytosol]
Phosphorylation of JAK2 (Homo sapiens)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Homo sapiens)
ADP [cytosol]
Phosphorylation of STATs (Homo sapiens)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Homo sapiens)
ADP [cytosol]
Regulation of KIT signaling (Homo sapiens)
PKC alpha interacts with and phosphorylates KIT (Homo sapiens)
ADP [cytosol]
Phosphorylation of APS (Homo sapiens)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
IGF1,2:IGF1R autophosphorylates (Homo sapiens)
ADP [cytosol]
IGF1R signaling cascade (Homo sapiens)
IRS-related events triggered by IGF1R (Homo sapiens)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Homo sapiens)
ADP [cytosol]
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
Activation of AKT2 (Homo sapiens)
PDPK1 phosphorylates AKT2 (Homo sapiens)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
PKB-mediated events (Homo sapiens)
PDE3B signalling (Homo sapiens)
p-T309,S474-AKT2:PIP3 phosphorylates PDE3B (Homo sapiens)
ADP [cytosol]
SHC-related events triggered by IGF1R (Homo sapiens)
IGF1R phosphorylates SHC1 (Homo sapiens)
ADP [cytosol]
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
AXL autophosphorylates on Y779 and Y821 (Homo sapiens)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Homo sapiens)
ADP [cytosol]
FYN autophosphorylates (Homo sapiens)
ADP [cytosol]
FYN phosphorylates PAK2 (Homo sapiens)
ADP [cytosol]
PAK2 autophorylates (Homo sapiens)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Homo sapiens)
ADP [cytosol]
PTK2 autophosphorylates (Homo sapiens)
ADP [cytosol]
PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)
ADP [cytosol]
Phosphorylation of SRC-1 (Homo sapiens)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Homo sapiens)
ADP [cytosol]
SRC-1 phosphorylates SHB (Homo sapiens)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Homo sapiens)
ADP [cytosol]
Src kinases phosphorylate VAV (Homo sapiens)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
ADP [cytosol]
VEGFR2 autophosphorylates (Homo sapiens)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Homo sapiens)
PDK1 phosphorylates PKC (Homo sapiens)
ADP [cytosol]
PKC autophosphorylates (Homo sapiens)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Homo sapiens)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Homo sapiens)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Homo sapiens)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Homo sapiens)
AKT1 phosphorylates eNOS (Homo sapiens)
ADP [cytosol]
PAK1-3 autophosphorylates (Homo sapiens)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Homo sapiens)
ADP [cytosol]
PDPK1 phosphorylates AKT at T308 (Homo sapiens)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Homo sapiens)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Homo sapiens)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Homo sapiens)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Homo sapiens)
ADP [cytosol]
p38 MAPK activation by VEGFR (Homo sapiens)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Homo sapiens)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
RHOBTB3 ATPase cycle (Homo sapiens)
RHOBTB3 hydrolyzes ATP (Homo sapiens)
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
ADP [cytosol]
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate Formins (Homo sapiens)
AURKB phosphorylates DIAPH2-2 at kinetochores (Homo sapiens)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Homo sapiens)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Homo sapiens)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Homo sapiens)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Homo sapiens)
ADP [cytosol]
PKC phosphorylates NCF1 (Homo sapiens)
ADP [cytosol]
RHO GTPases Activate ROCKs (Homo sapiens)
LIM kinase phosphorylation by ROCK (Homo sapiens)
ADP [cytosol]
LIMK phosphorylates CFL1, inactivating it (Homo sapiens)
ADP [cytosol]
Myosin phosphatase inactivation by ROCK (Homo sapiens)
ADP [cytosol]
Myosin regulatory light chain phosphorylation by ROCK (Homo sapiens)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Detachment of WASP/WAVE (Homo sapiens)
Mother filament:ARP2/3:actin:ADP [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Homo sapiens)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
ADP [cytosol]
RHO GTPases activate CIT (Homo sapiens)
Activated CIT phosphorylates MRLCs (Homo sapiens)
ADP [cytosol]
RHO GTPases activate PAKs (Homo sapiens)
Autophosphorylation of PAK1,2,3 (Homo sapiens)
ADP [cytosol]
MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex (Homo sapiens)
ADP [cytosol]
PAK phosphorylates cortactin (Homo sapiens)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Homo sapiens)
ADP [cytosol]
PAK1 phosphorylates FLNA (Homo sapiens)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Homo sapiens)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Homo sapiens)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Homo sapiens)
ADP [cytosol]
RHO GTPases activate PKNs (Homo sapiens)
PDPK1 phosphorylates PKN1,2,3 (Homo sapiens)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Homo sapiens)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Homo sapiens)
ADP [cytosol]
RHO GTPase cycle (Homo sapiens)
RHOU GTPase cycle (Homo sapiens)
SRC phosphorylates RHOU (Homo sapiens)
ADP [cytosol]
Signaling by TGFB family members (Homo sapiens)
Signaling by Activin (Homo sapiens)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)
ADP [cytosol]
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin (Homo sapiens)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Homo sapiens)
ADP [cytosol]
Signaling by BMP (Homo sapiens)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Homo sapiens)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Homo sapiens)
TGF-beta receptor signaling activates SMADs (Homo sapiens)
Activated type I receptor phosphorylates SMAD2/3 directly (Homo sapiens)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Homo sapiens)
ADP [cytosol]
TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Homo sapiens)
TGFBR2 phosphorylates TGFBR1 and PARD6A (Homo sapiens)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Homo sapiens)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Homo sapiens)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Homo sapiens)
ADP [cytosol]
Signaling by WNT (Homo sapiens)
Beta-catenin independent WNT signaling (Homo sapiens)
Ca2+ pathway (Homo sapiens)
Activation of MAP3K7 in response to WNT (Homo sapiens)
ADP [cytosol]
Activation of NLK (Homo sapiens)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Homo sapiens)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Homo sapiens)
ADP [cytosol]
PCP/CE pathway (Homo sapiens)
VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)
ADP [cytosol]
WNT-dependent phosphorylation of DVL (Homo sapiens)
ADP [cytosol]
WNT5A-dependent internalization of FZD4 (Homo sapiens)
DVL2 is phosphorylated by PKC (Homo sapiens)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Homo sapiens)
AXIN is phosphorylated in the destruction complex (Homo sapiens)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Homo sapiens)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Homo sapiens)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Homo sapiens)
ADP [cytosol]
TCF dependent signaling in response to WNT (Homo sapiens)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Homo sapiens)
Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI (Homo sapiens)
ADP [cytosol]
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Homo sapiens)
ADP [cytosol]
WNT mediated activation of DVL (Homo sapiens)
CSNK2-mediated phosphorylation of DVL (Homo sapiens)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Homo sapiens)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Homo sapiens)
ADP [cytosol]
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
ABC transporters in lipid homeostasis (Homo sapiens)
ABCA12 transports lipids from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Homo sapiens)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Homo sapiens)
ADP [cytosol]
ABCA7:Apo1A-mediated phospholipid efflux (Homo sapiens)
ADP [cytosol]
ABCAs mediate lipid efflux (Homo sapiens)
ADP [cytosol]
ABCAs mediate lipid influx (Homo sapiens)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Homo sapiens)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Homo sapiens)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCA4 mediates atRAL transport (Homo sapiens)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Homo sapiens)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Homo sapiens)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
HCO3- transport through ion channel (Homo sapiens)
ADP [cytosol]
Mitochondrial ABC transporters (Homo sapiens)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Homo sapiens)
ADP [cytosol]
The ABCC family mediates organic anion transport (Homo sapiens)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Homo sapiens)
ADP [cytosol]
Aquaporin-mediated transport (Homo sapiens)
Vasopressin regulates renal water homeostasis via Aquaporins (Homo sapiens)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Homo sapiens)
ADP [cytosol]
Ion channel transport (Homo sapiens)
Ion transport by P-type ATPases (Homo sapiens)
ATP12A:ATP4B exchanges K+ for H+ (Homo sapiens)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Homo sapiens)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Homo sapiens)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Homo sapiens)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Homo sapiens)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Homo sapiens)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Homo sapiens)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Homo sapiens)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Homo sapiens)
ADP [cytosol]
Stimuli-sensing channels (Homo sapiens)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)
ADP [cytosol]
Iron uptake and transport (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
ADP [cytosol]
Transferrin endocytosis and recycling (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Homo sapiens)
Plasma lipoprotein assembly (Homo sapiens)
HDL assembly (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Homo sapiens)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Homo sapiens)
ADP [cytosol]
Plasma lipoprotein remodeling (Homo sapiens)
HDL remodeling (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ADP [cytosol]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
ADP [cytosol]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Clathrin-mediated endocytosis (Homo sapiens)
AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Homo sapiens)
ADBRK1,2 phosphorylate AVPR2 (Homo sapiens)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Homo sapiens)
clathrin:HSPA8:ADP [cytosol] (Homo sapiens)
HSPA8:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Homo sapiens)
ADP [cytosol]
ER to Golgi Anterograde Transport (Homo sapiens)
COPI-mediated anterograde transport (Homo sapiens)
GBF1 stimulates ARF nucleotide exchange (Homo sapiens)
ADP [cytosol]
COPII-mediated vesicle transport (Homo sapiens)
CSNK1D phosphorylates SEC23 (Homo sapiens)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Homo sapiens)
ESCRT Disassembly (Homo sapiens)
ADP [cytosol]
Gap junction trafficking and regulation (Homo sapiens)
Regulation of gap junction activity (Homo sapiens)
Phosphorylation of Cx43 by c-src (Homo sapiens)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Homo sapiens)
Golgi-to-ER retrograde transport (Homo sapiens)
COPI-independent Golgi-to-ER retrograde traffic (Homo sapiens)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Homo sapiens)
ADP [cytosol]
Intra-Golgi traffic (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
ADP [cytosol]
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Homo sapiens)
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
ADP [cytosol]
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Homo sapiens)
ADP [cytosol]
Rab regulation of trafficking (Homo sapiens)
RAB GEFs exchange GTP for GDP on RABs (Homo sapiens)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Homo sapiens)
ADP [cytosol]
p-ULK1 phosphorylates DENND3 (Homo sapiens)
ADP [cytosol]
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
AMPK-alpha2 phosphorylates TBC1D1 (Homo sapiens)
ADP [cytosol]
RALA:GTP binds MYO1C:CALM1 and activates MYO1C (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
f-actin (ADP) [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
f-actin (ADP) [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)
ADP [cytosol]
SLC2A4 (GLUT4) vesicle translocates and docks at the plasma membrane (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
f-actin (ADP) [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
GGC-RALA:GTP:MYO1C:Exocyst [plasma membrane] (Homo sapiens)
GGC-RALA:GTP:MYO1C:Calmodulin:F-actin [cytoplasmic vesicle membrane] (Homo sapiens)
f-actin (ADP) [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Homo sapiens)
ADP [cytosol]
p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) (Homo sapiens)
ADP [cytosol]
p-AKT2 phosphorylates C2CD5 (Homo sapiens)
ADP [cytosol]
p-AKT2 phosphorylates Myosin 5A (Homo sapiens)
ADP [cytosol]
p-AKT2 phosphorylates RGC2 (Homo sapiens)
ADP [cytosol]
trans-Golgi Network Vesicle Budding (Homo sapiens)
Golgi Associated Vesicle Biogenesis (Homo sapiens)
trans-Golgi Network Derived Vesicle Uncoating (Homo sapiens)
ADP [cytosol]
Lysosome Vesicle Biogenesis (Homo sapiens)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Homo sapiens)
ADP [cytosol]
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
AMPK (complex) phosphorylates ULK1 (complex) (Mus musculus)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Mus musculus)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Mus musculus)
ADP [cytosol]
Selective autophagy (Mus musculus)
Mitophagy (Mus musculus)
Receptor Mediated Mitophagy (Mus musculus)
FUNDC1 is phosphorylated by CK2 (Mus musculus)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Mus musculus)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Mus musculus)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Mus musculus)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Mus musculus)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Mus musculus)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)
ADP [cytosol]
Cell Cycle (Mus musculus)
Cell Cycle Checkpoints (Mus musculus)
G2/M Checkpoints (Mus musculus)
G2/M DNA replication checkpoint (Mus musculus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Mus musculus)
ADP [cytosol]
Cell Cycle, Mitotic (Mus musculus)
M Phase (Mus musculus)
Mitotic Metaphase and Anaphase (Mus musculus)
Mitotic Anaphase (Mus musculus)
Nuclear Envelope (NE) Reassembly (Mus musculus)
Initiation of Nuclear Envelope (NE) Reformation (Mus musculus)
CDK1 phosphorylates LBR (Mus musculus)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Mus musculus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Mus musculus)
ADP [cytosol]
Mitotic Prometaphase (Mus musculus)
Condensation of Prometaphase Chromosomes (Mus musculus)
CK2 phosphorylates condensin I subunits (Mus musculus)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Mus musculus)
PLK1 phosphorylates NUDC (Mus musculus)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Mus musculus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Mus musculus)
ADP [cytosol]
Mitotic Prophase (Mus musculus)
Golgi Cisternae Pericentriolar Stack Reorganization (Mus musculus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Mus musculus)
ADP [cytosol]
Nuclear Envelope Breakdown (Mus musculus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Mus musculus)
CDK1:CCNB phosphorylates NEK9 (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Mus musculus)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Mus musculus)
CDK1 phosphorylates NUP98 (Mus musculus)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Mus musculus)
G1 Phase (Mus musculus)
Cyclin D associated events in G1 (Mus musculus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Mus musculus)
ADP [cytosol]
G1/S Transition (Mus musculus)
Cyclin E associated events during G1/S transition (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Mus musculus)
PTK6 phosphorylates CDKN1B (Mus musculus)
ADP [cytosol]
Mitotic G2-G2/M phases (Mus musculus)
G2/M Transition (Mus musculus)
AURKA Activation by TPX2 (Mus musculus)
TPX2 promotes AURKA autophosphorylation (Mus musculus)
ADP [cytosol]
Centrosome maturation (Mus musculus)
Loss of proteins required for interphase microtubule organization from the centrosome (Mus musculus)
Loss of Nlp from mitotic centrosomes (Mus musculus)
Plk1-mediated phosphorylation of Nlp (Mus musculus)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Mus musculus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Mus musculus)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Mus musculus)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Mus musculus)
AURKA phosphorylates PHLDA1 (Mus musculus)
ADP [cytosol]
Polo-like kinase mediated events (Mus musculus)
Activation of Cdc25C (Mus musculus)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Mus musculus)
AJUBA facilitates AURKA autophosphorylation (Mus musculus)
ADP [cytosol]
AURKA phosphorylates PLK1 (Mus musculus)
ADP [cytosol]
CDK1 phosphorylates BORA (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates BORA (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates OPTN (Mus musculus)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Mus musculus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Mus musculus)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Mus musculus)
ADP [cytosol]
S Phase (Mus musculus)
Cyclin A:Cdk2-associated events at S phase entry (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Mus musculus)
PTK6 phosphorylates CDKN1B (Mus musculus)
ADP [cytosol]
Cell-Cell communication (Mus musculus)
Nephrin family interactions (Mus musculus)
Phosphorylation of nephrin by FYN (Mus musculus)
ADP [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular Senescence (Mus musculus)
Oxidative Stress Induced Senescence (Mus musculus)
MAP3K5 phosphorylates MKK3 and MKK6 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Cellular response to chemical stress (Mus musculus)
KEAP1-NFE2L2 pathway (Mus musculus)
Nuclear events mediated by NFE2L2 (Mus musculus)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Mus musculus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Mus musculus)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Mus musculus)
ADP [cytosol]
Cellular response to heat stress (Mus musculus)
Regulation of HSF1-mediated heat shock response (Mus musculus)
Constitutive phosphorylation by pERK1/2 (Mus musculus)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Mus musculus)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Mus musculus)
ADP [cytosol]
HSP70s:ADP [cytosol] (Mus musculus)
HSP13:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP14:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Mus musculus)
HSP70s:ADP [cytosol] (Mus musculus)
HSP13:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP14:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Mus musculus)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Mus musculus)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Mus musculus)
ATP binding to HSP90 triggers conformation change (Mus musculus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
ATP hydrolysis by HSP70 (Mus musculus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Mus musculus)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Mus musculus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Mus musculus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Mus musculus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Mus musculus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Mus musculus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Mus musculus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Unfolded Protein Response (UPR) (Mus musculus)
IRE1alpha activates chaperones (Mus musculus)
IRE1 dimer autophosphorylates (Mus musculus)
ADP [cytosol]
PERK regulates gene expression (Mus musculus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Mus musculus)
ADP [cytosol]
DNA Replication (Mus musculus)
DNA Replication Pre-Initiation (Mus musculus)
Assembly of the pre-replicative complex (Mus musculus)
Assembly of the ORC complex at the origin of replication (Mus musculus)
ORC6 is phosphorylated on T195 (Mus musculus)
ADP [cytosol]
Developmental Biology (Mus musculus)
MITF-M-regulated melanocyte development (Mus musculus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Mus musculus)
MAPK-dependent phosphorylation of KARS (Mus musculus)
ADP [cytosol]
Nervous system development (Mus musculus)
Axon guidance (Mus musculus)
EPH-Ephrin signaling (Mus musculus)
EPH receptors autophosphorylate (Mus musculus)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Mus musculus)
SFKs phosphorylate VAV2,3 (Mus musculus)
ADP [cytosol]
EPHB-mediated forward signaling (Mus musculus)
EPHB phosphorylates TIAM1 (Mus musculus)
ADP [cytosol]
PAK1 autophosphorylates (Mus musculus)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Mus musculus)
ADP [cytosol]
Ephrin signaling (Mus musculus)
PAKs autophosphorylate (Mus musculus)
ADP [cytosol]
L1CAM interactions (Mus musculus)
Recycling pathway of L1 (Mus musculus)
Phosphorylation of L1 by ERK (Mus musculus)
ADP [cytosol]
Phosphorylation of L1 by SRC (Mus musculus)
ADP [cytosol]
Signal transduction by L1 (Mus musculus)
Interaction of PAK1 with Rac1-GTP (Mus musculus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Mus musculus)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Mus musculus)
ADP [cytosol]
Phosphorylation of L1 by CK-II (Mus musculus)
ADP [cytosol]
Netrin-1 signaling (Mus musculus)
DCC mediated attractive signaling (Mus musculus)
Phosphorylation of DCC by Fyn (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Mus musculus)
ADP [cytosol]
RET signaling (Mus musculus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Mus musculus)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Mus musculus)
ADP [cytosol]
RET tyrosine phosphorylation (Mus musculus)
ADP [cytosol]
Reelin signalling pathway (Mus musculus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Mus musculus)
ADP [cytosol]
Semaphorin interactions (Mus musculus)
CRMPs in Sema3A signaling (Mus musculus)
Phosphorylation of CRMPs by Cdk5 (Mus musculus)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Mus musculus)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Mus musculus)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Mus musculus)
Autophosphorylation of PAK (Mus musculus)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Mus musculus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Mus musculus)
ADP [cytosol]
Sema4D in semaphorin signaling (Mus musculus)
Sema4D induced cell migration and growth-cone collapse (Mus musculus)
SEMA4D interacts with Plexin-B1:ErbB2 (Mus musculus)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Mus musculus)
SEMA4D interacts with Plexin-B1:Met (Mus musculus)
ADP [cytosol]
Signaling by ROBO receptors (Mus musculus)
Role of ABL in ROBO-SLIT signaling (Mus musculus)
Phosphorylation of ROBO1 by ABL kinase (Mus musculus)
ADP [cytosol]
Drug ADME (Mus musculus)
Aspirin ADME (Mus musculus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Mus musculus)
ADP [cytosol]
Azathioprine ADME (Mus musculus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Mus musculus)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Mus musculus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Mus musculus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Mus musculus)
ADP [cytosol]
Ciprofloxacin ADME (Mus musculus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Mus musculus)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Mus musculus)
ADP [cytosol]
Paracetamol ADME (Mus musculus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Mus musculus)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Mus musculus)
ADP [cytosol]
Prednisone ADME (Mus musculus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Mus musculus)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Mus musculus)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Mus musculus)
ADP [cytosol]
Ribavirin ADME (Mus musculus)
ADK phosphorylates RBV (Mus musculus)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Mus musculus)
ADP [cytosol]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
Regulation of TP53 Activity (Mus musculus)
Regulation of TP53 Expression and Degradation (Mus musculus)
Regulation of TP53 Degradation (Mus musculus)
AKT phosphorylates MDM2 (Mus musculus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Mus musculus)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Mus musculus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Mus musculus)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Mus musculus)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Mus musculus)
PLK2 phosphorylates CENPJ (Mus musculus)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Mus musculus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Mus musculus)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Mus musculus)
Regulation of RUNX3 expression and activity (Mus musculus)
SRC phosphorylates RUNX3 (Mus musculus)
ADP [cytosol]
Hemostasis (Mus musculus)
Cell surface interactions at the vascular wall (Mus musculus)
PECAM1 interactions (Mus musculus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Mus musculus)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Mus musculus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Mus musculus)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Mus musculus)
ADP [cytosol]
Kinesins (Mus musculus)
Kinesins move along microtubules consuming ATP (Mus musculus)
ADP [cytosol]
Platelet activation, signaling and aggregation (Mus musculus)
Effects of PIP2 hydrolysis (Mus musculus)
DAG kinase produces phosphatidic acid from DAG (Mus musculus)
ADP [cytosol]
GPVI-mediated activation cascade (Mus musculus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Mus musculus)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
SYK autophosphorylates (Mus musculus)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Mus musculus)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Mus musculus)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Mus musculus)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Mus musculus)
Integrin signaling (Mus musculus)
Autophosphorylation of PTK2 at Y397 (Mus musculus)
ADP [cytosol]
Autophosphorylation of SRC (Mus musculus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Mus musculus)
ADP [cytosol]
SYK activation by SRC (Mus musculus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Mus musculus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Mus musculus)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Mus musculus)
Disinhibition of SNARE formation (Mus musculus)
Phosphorylation of Platelet Sec-1 (Mus musculus)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Mus musculus)
ADP [cytosol]
Platelet degranulation (Mus musculus)
ABCC4 accumulation of dense granule contents (Mus musculus)
ADP [cytosol]
Signal amplification (Mus musculus)
ADP signalling through P2Y purinoceptor 1 (Mus musculus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Mus musculus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Mus musculus)
ADP [cytosol]
Platelet homeostasis (Mus musculus)
Platelet sensitization by LDL (Mus musculus)
FGR binds and phosphorylates LRP8 (Mus musculus)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Mus musculus)
ADP [cytosol]
PECAM1 is phosphorylated (Mus musculus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Mus musculus)
ADP [cytosol]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Mus musculus)
Transport of Antigen peptide in to ER (Mus musculus)
ADP [cytosol]
Costimulation by the CD28 family (Mus musculus)
CD28 co-stimulation (Mus musculus)
CD28 dependent PI3K/Akt signaling (Mus musculus)
AKT interacts and phosphorylates Cot (Mus musculus)
ADP [cytosol]
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Mus musculus)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Mus musculus)
ADP [cytosol]
CD28 dependent Vav1 pathway (Mus musculus)
Activation of Vav1 (Mus musculus)
ADP [cytosol]
Phosphorylation of CD28 (Mus musculus)
ADP [cytosol]
CTLA4 inhibitory signaling (Mus musculus)
Phosphorylation of CTLA-4 (Mus musculus)
ADP [cytosol]
PD-1 signaling (Mus musculus)
Phosphorylation of PD-1 (Mus musculus)
ADP [cytosol]
MHC class II antigen presentation (Mus musculus)
Transport of antigen loaded MHC II molecules to surface (Mus musculus)
ADP [cytosol]
Rap1 signalling (Mus musculus)
PKA/PKG phosphorylate Rap1GAP2 (Mus musculus)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Mus musculus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Mus musculus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Mus musculus)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Mus musculus)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Mus musculus)
ADP [cytosol]
CD22 mediated BCR regulation (Mus musculus)
LYN phosphorylates CD22 (Mus musculus)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Mus musculus)
Activation of NF-kappaB in B cells (Mus musculus)
Activated IKK phosphorylates I-kappaB (Mus musculus)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Mus musculus)
ADP [cytosol]
TCR signaling (Mus musculus)
Downstream TCR signaling (Mus musculus)
Activation of IKK complex (Mus musculus)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Mus musculus)
ADP [cytosol]
Change of PKC theta conformation (Mus musculus)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phosphorylation of Bcl10 (Mus musculus)
ADP [cytosol]
Phosphorylation of CARMA1 (Mus musculus)
ADP [cytosol]
Phosphorylation of PKC theta (Mus musculus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
ADP [cytosol]
Generation of second messenger molecules (Mus musculus)
Phosphorylation of PLC-gamma1 (Mus musculus)
ADP [cytosol]
Phosphorylation of SLP-76 (Mus musculus)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Mus musculus)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Mus musculus)
Activation of Lck (Mus musculus)
ADP [cytosol]
Inactivation of Lck by Csk (Mus musculus)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Mus musculus)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Mus musculus)
Activation of ZAP-70 (Mus musculus)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Mus musculus)
ADP [cytosol]
Cytokine Signaling in Immune system (Mus musculus)
FLT3 Signaling (Mus musculus)
Active FLT3 phosphorylates CDKN1B (Mus musculus)
ADP [cytosol]
FLT3 phosphorylates GRB10 (Mus musculus)
ADP [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Mus musculus)
ADP [cytosol]
Negative regulation of FLT3 (Mus musculus)
FLT3 phosphorylates CBL (Mus musculus)
ADP [cytosol]
Growth hormone receptor signaling (Mus musculus)
JAK2 phosphorylation (Mus musculus)
ADP [cytosol]
JAK2 phosphorylation of GHR (Mus musculus)
ADP [cytosol]
Lyn activates ERK (Mus musculus)
ADP [cytosol]
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
PKR-mediated signaling (Mus musculus)
p-PKR dimer phosphorylates CDK1 (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates MAPT (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Mus musculus)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Mus musculus)
ADP [cytosol]
Interferon alpha/beta signaling (Mus musculus)
Activation of JAK kinases (Mus musculus)
ADP [cytosol]
Formation of p-STAT1 homodimer (Mus musculus)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Mus musculus)
ADP [cytosol]
Phosphorylation of STAT2 (Mus musculus)
ADP [cytosol]
Interferon gamma signaling (Mus musculus)
IFNG signaling activates MAPKs (Mus musculus)
JAK1-activated RAF1 phosphorylates MAPKs (Mus musculus)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Mus musculus)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Mus musculus)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Mus musculus)
ADP [cytosol]
Phosphorylation of JAK2 (Mus musculus)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Mus musculus)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Mus musculus)
ADP [cytosol]
Transphosphorylation of JAK1 (Mus musculus)
ADP [cytosol]
Prolactin receptor signaling (Mus musculus)
JAK2 phosphorylation (Mus musculus)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Mus musculus)
ADP [cytosol]
Signaling by Interleukins (Mus musculus)
Interleukin-1 family signaling (Mus musculus)
Interleukin-1 signaling (Mus musculus)
IKBA is phosphorylated by Phospho IKKB kinase (Mus musculus)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Mus musculus)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Mus musculus)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Mus musculus)
ADP [cytosol]
Interleukin-37 signaling (Mus musculus)
STAT3 phosphorylation (Mus musculus)
ADP [cytosol]
TBK1 phosphorylation (Mus musculus)
ADP [cytosol]
Interleukin-38 signaling (Mus musculus)
MAPK8 phosphorylation (Mus musculus)
ADP [cytosol]
Interleukin-10 signaling (Mus musculus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Mus musculus)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Mus musculus)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Mus musculus)
ADP [cytosol]
Interleukin-12 family signaling (Mus musculus)
Interleukin-12 signaling (Mus musculus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Mus musculus)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Mus musculus)
ADP [cytosol]
Interleukin-23 signaling (Mus musculus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Mus musculus)
ADP [cytosol]
Interleukin-27 signaling (Mus musculus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Mus musculus)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Mus musculus)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Mus musculus)
ADP [cytosol]
Interleukin-35 Signalling (Mus musculus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Mus musculus)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Mus musculus)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Mus musculus)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Mus musculus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Mus musculus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Mus musculus)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Mus musculus)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Mus musculus)
ADP [cytosol]
Interleukin-17 signaling (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
Interleukin-2 family signaling (Mus musculus)
Interleukin receptor SHC signaling (Mus musculus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Mus musculus)
ADP [cytosol]
Interleukin-15 signaling (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Mus musculus)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Mus musculus)
ADP [cytosol]
Interleukin-2 signaling (Mus musculus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Mus musculus)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Mus musculus)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Mus musculus)
ADP [cytosol]
SYK is a substrate for JAK1 (Mus musculus)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)
ADP [cytosol]
Interleukin-21 signaling (Mus musculus)
IL21 receptor JAK phosphorylation (Mus musculus)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Mus musculus)
ADP [cytosol]
Interleukin-9 signaling (Mus musculus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Mus musculus)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Mus musculus)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Mus musculus)
ADP [cytosol]
Interleukin-20 family signaling (Mus musculus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Mus musculus)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Mus musculus)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Mus musculus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Mus musculus)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Mus musculus)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Mus musculus)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Mus musculus)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Mus musculus)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Mus musculus)
Activation of STAT5a/b by JAK2 (Mus musculus)
ADP [cytosol]
Interleukin receptor SHC signaling (Mus musculus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Mus musculus)
ADP [cytosol]
JAK2 is phosphorylated, activated (Mus musculus)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Mus musculus)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Mus musculus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Mus musculus)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Mus musculus)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Mus musculus)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Mus musculus)
ADP [cytosol]
Interleukin-6 family signaling (Mus musculus)
Interleukin-6 signaling (Mus musculus)
IL6ST is tyrosine phosphorylated (Mus musculus)
ADP [cytosol]
JAK activation (Mus musculus)
ADP [cytosol]
PTPN11 is phosphorylated (Mus musculus)
ADP [cytosol]
Serine phosphorylation of STATs (Mus musculus)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)
ADP [cytosol]
Interleukin-7 signaling (Mus musculus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Mus musculus)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Mus musculus)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Mus musculus)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Mus musculus)
NIK-->noncanonical NF-kB signaling (Mus musculus)
Active NIK phosphorylates IKKA dimer (Mus musculus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Mus musculus)
ADP [cytosol]
NIK autophosphorylates on T559 (Mus musculus)
ADP [cytosol]
Innate Immune System (Mus musculus)
Alpha-protein kinase 1 signaling pathway (Mus musculus)
ALPK1 phosphorylates TIFA (Mus musculus)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Mus musculus)
ADP [cytosol]
Antimicrobial peptides (Mus musculus)
Ion influx/efflux at host-pathogen interface (Mus musculus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Mus musculus)
ADP [cytosol]
C-type lectin receptors (CLRs) (Mus musculus)
CD209 (DC-SIGN) signaling (Mus musculus)
PAK phosphorylates p21 RAF1 on S338 (Mus musculus)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Mus musculus)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Mus musculus)
Dectin-1 mediated noncanonical NF-kB signaling (Mus musculus)
Active NIK phosphorylates IKKA dimer (Mus musculus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Mus musculus)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Mus musculus)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Mus musculus)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Mus musculus)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Mus musculus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
ADP [cytosol]
Dectin-2 family (Mus musculus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Mus musculus)
ADP [cytosol]
SYK autophosphorylates (Mus musculus)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Mus musculus)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Mus musculus)
STING mediated induction of host immune responses (Mus musculus)
IRF3-mediated induction of type I IFN (Mus musculus)
IRF3 is phosphorylated by TBK1 (Mus musculus)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Mus musculus)
ADP [cytosol]
STAT6-mediated induction of chemokines (Mus musculus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Mus musculus)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Mus musculus)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Mus musculus)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Mus musculus)
RIP-mediated NFkB activation via ZBP1 (Mus musculus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
DAP12 interactions (Mus musculus)
DAP12 signaling (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of SYK (Mus musculus)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Mus musculus)
TRAF6 mediated NF-kB activation (Mus musculus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Mus musculus)
Autophosphorylation of LYN kinase (Mus musculus)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Mus musculus)
Autophosphorylation of BTK/ITK (Mus musculus)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Mus musculus)
ADP [cytosol]
FCERI mediated MAPK activation (Mus musculus)
Autophosphorylation of PAK (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of VAV (Mus musculus)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Mus musculus)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Mus musculus)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Mus musculus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
FCERI mediated NF-kB activation (Mus musculus)
Activation of TAK1 complex bound to pUb-TRAF6 (Mus musculus)
ADP [cytosol]
Autophosphorylation of PKC-theta (Mus musculus)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Mus musculus)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Mus musculus)
ADP [cytosol]
Phosphorylation of PKC-theta (Mus musculus)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Mus musculus)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Mus musculus)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Mus musculus)
Phosphorylation of NTAL by p-SYK/Lyn (Mus musculus)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Mus musculus)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Mus musculus)
FCGR activation (Mus musculus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Mus musculus)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Mus musculus)
ABL phosphorylates WAVEs (Mus musculus)
ADP [cytosol]
Autophosphorylation of PAK1 (Mus musculus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Mus musculus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Mus musculus)
Actin:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Detachment of WASP/WAVE (Mus musculus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Mus musculus)
Actin:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Mus musculus)
Actin filament bound Myosin-X [plasma membrane] (Mus musculus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Mus musculus)
ADP [cytosol]
Phosphorylation of VAV (Mus musculus)
ADP [cytosol]
Role of myosins in phagosome formation (Mus musculus)
Myosin-Actin filaments [cytosol] (Mus musculus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Mus musculus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Mus musculus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Mus musculus)
ADP [cytosol]
Role of phospholipids in phagocytosis (Mus musculus)
DAG stimulates protein kinase C-delta (Mus musculus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of PLCG (Mus musculus)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Mus musculus)
NOD1/2 Signaling Pathway (Mus musculus)
Activation of p38 MAPK (Mus musculus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Mus musculus)
ADP [cytosol]
Toll-like Receptor Cascades (Mus musculus)
Toll Like Receptor 10 (TLR10) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Mus musculus)
Toll Like Receptor TLR1:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Mus musculus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Mus musculus)
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Mus musculus)
MyD88-independent TLR4 cascade (Mus musculus)
TRIF (TICAM1)-mediated TLR4 signaling (Mus musculus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Mus musculus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Mus musculus)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Mus musculus)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Mus musculus)
Activation of TAK1 complex bound to activated TLR4 complex (Mus musculus)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Mus musculus)
MyD88 cascade initiated on plasma membrane (Mus musculus)
IRAK1 recruits IKK complex (Mus musculus)
IRAK1 phosphorylates Pellino (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Mus musculus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Mus musculus)
MyD88 dependent cascade initiated on endosome (Mus musculus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Mus musculus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Mus musculus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Mus musculus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Mus musculus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Mus musculus)
ADP [cytosol]
MAP kinase activation (Mus musculus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
ADP [cytosol]
MAP3K8 is phosphorylated (Mus musculus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
ADP [cytosol]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Pyruvate metabolism (Mus musculus)
PKM dephosphorylates PEP to PYR (Mus musculus)
ADP [cytosol]
Regulation of pyruvate metabolism (Mus musculus)
NEK1 phosphorylates ME1 (Mus musculus)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Mus musculus)
Mitochondrial Uncoupling (Mus musculus)
The proton buffering model (Mus musculus)
Protons are translocated from the intermembrane space to the matrix (Mus musculus)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
Transport and synthesis of PAPS (Mus musculus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Mus musculus)
ADP [cytosol]
Glutathione conjugation (Mus musculus)
Glutathione synthesis and recycling (Mus musculus)
GCL ligates L-Glu to L-Cys (Mus musculus)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Mus musculus)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Mus musculus)
ADP [cytosol]
Inositol phosphate metabolism (Mus musculus)
Synthesis of IP3 and IP4 in the cytosol (Mus musculus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Mus musculus)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Mus musculus)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Mus musculus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Mus musculus)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Mus musculus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Mus musculus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Mus musculus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Mus musculus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Mus musculus)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Mus musculus)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Mus musculus)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Mus musculus)
ADP [cytosol]
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Acetylcholine regulates insulin secretion (Mus musculus)
Protein kinase C, alpha type phosphorylates MARCKS (Mus musculus)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Mus musculus)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Creatine metabolism (Mus musculus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Mus musculus)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Mus musculus)
ADP [cytosol]
Glutamate and glutamine metabolism (Mus musculus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Mus musculus)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Mus musculus)
ADP [cytosol]
Histidine catabolism (Mus musculus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Mus musculus)
ADP [cytosol]
Metabolism of carbohydrates (Mus musculus)
Formation of xylulose-5-phosphate (Mus musculus)
XYLB phosphorylates D-xylulose (Mus musculus)
ADP [cytosol]
Fructose metabolism (Mus musculus)
Fructose catabolism (Mus musculus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Mus musculus)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Mus musculus)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)
ADP [cytosol]
Galactose catabolism (Mus musculus)
GALK1 phosphorylates Gal to Gal1P (Mus musculus)
ADP [cytosol]
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Mus musculus)
ADP [cytosol]
Glycolysis (Mus musculus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Mus musculus)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Mus musculus)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Mus musculus)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Mus musculus)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Mus musculus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Mus musculus)
ADP [cytosol]
Glycogen metabolism (Mus musculus)
Glycogen breakdown (glycogenolysis) (Mus musculus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Mus musculus)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Mus musculus)
ADP [cytosol]
Glycosaminoglycan metabolism (Mus musculus)
Transport and synthesis of PAPS (Mus musculus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Mus musculus)
ADP [cytosol]
Pentose phosphate pathway (Mus musculus)
RBKS phosphorylates ribose to R5P (Mus musculus)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Mus musculus)
ADP [cytosol]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Arachidonic acid metabolism (Mus musculus)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Mus musculus)
ALOX5 is phosphorylated by MAPKAP2 (Mus musculus)
ADP [cytosol]
Carnitine metabolism (Mus musculus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Mus musculus)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Mus musculus)
ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Mus musculus)
ADP [cytosol]
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Recycling of bile acids and salts (Mus musculus)
ABCB11 transports bile salts from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
ABCB11 transports bile salts from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
Cholesterol biosynthesis (Mus musculus)
MVD decarboxylates MVA5PP to IPPP (Mus musculus)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Mus musculus)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Mus musculus)
ADP [cytosol]
Phospholipid metabolism (Mus musculus)
Glycerophospholipid biosynthesis (Mus musculus)
Synthesis of PC (Mus musculus)
Casein kinase II phosphorylates STARD10 (Mus musculus)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Mus musculus)
ADP [cytosol]
Synthesis of PE (Mus musculus)
ETA is phosphorylated to PETA by CHK/ETNK (Mus musculus)
ADP [cytosol]
PI Metabolism (Mus musculus)
Synthesis of PIPs at the ER membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Mus musculus)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Mus musculus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Mus musculus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Mus musculus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Mus musculus)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Mus musculus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Mus musculus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Mus musculus)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Mus musculus)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Mus musculus)
BMX phosphorylates RUFY1 (Mus musculus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Mus musculus)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Mus musculus)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Mus musculus)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Mus musculus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Mus musculus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Mus musculus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Mus musculus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Mus musculus)
ADP [cytosol]
Sphingolipid metabolism (Mus musculus)
Glycosphingolipid metabolism (Mus musculus)
Glycosphingolipid biosynthesis (Mus musculus)
CERK phosphorylates CERA to form C1P (Mus musculus)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Mus musculus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Mus musculus)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Mus musculus)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Mus musculus)
ADP [cytosol]
Triglyceride metabolism (Mus musculus)
Triglyceride biosynthesis (Mus musculus)
Conversion of Glycerol to Glycerol-3-phosphate (Mus musculus)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Mus musculus)
eNOS activation (Mus musculus)
AKT1 phosphorylates eNOS (Mus musculus)
ADP [cytosol]
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Mus musculus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Mus musculus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Mus musculus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Mus musculus)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Mus musculus)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Mus musculus)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Mus musculus)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Mus musculus)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Mus musculus)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Mus musculus)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Mus musculus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Mus musculus)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Mus musculus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Mus musculus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Mus musculus)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Mus musculus)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Mus musculus)
ADP [cytosol]
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Mus musculus)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Mus musculus)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Mus musculus)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Mus musculus)
ADP [cytosol]
Pyrimidine biosynthesis (Mus musculus)
CAD hexamer transforms L-Gln to CAP (Mus musculus)
ADP [cytosol]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Mus musculus)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Mus musculus)
ADP [cytosol]
Pyrimidine catabolism (Mus musculus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Mus musculus)
ADP [cytosol]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Mus musculus)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Mus musculus)
ADP [cytosol]
Pyrimidine salvage (Mus musculus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Mus musculus)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Mus musculus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Mus musculus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Mus musculus)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Mus musculus)
ADP [cytosol]
Metabolism of porphyrins (Mus musculus)
Heme biosynthesis (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
Heme degradation (Mus musculus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Mus musculus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Mus musculus)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Mus musculus)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Transport of RCbl within the body (Mus musculus)
ABCC1 transports cytosolic RCbl to extracellular region (Mus musculus)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Mus musculus)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Mus musculus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Mus musculus)
ADP [cytosol]
Metabolism of folate and pterines (Mus musculus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Mus musculus)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Mus musculus)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Mus musculus)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Mus musculus)
ADP [cytosol]
Nicotinate metabolism (Mus musculus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Mus musculus)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Mus musculus)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Mus musculus)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Mus musculus)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Mus musculus)
RFK:Mg2+ phosphorylates RIB (Mus musculus)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Mus musculus)
Coenzyme A biosynthesis (Mus musculus)
COASY phosphorylates DP-CoA (Mus musculus)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Mus musculus)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Mus musculus)
ADP [cytosol]
PANK2 phosphorylates PanK (Mus musculus)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Mus musculus)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Mus musculus)
2xPDKX:2xZn2+ phosphorylates PDX (Mus musculus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Mus musculus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Mus musculus)
ADP [cytosol]
Metabolism of RNA (Mus musculus)
Nonsense-Mediated Decay (NMD) (Mus musculus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Mus musculus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Mus musculus)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Mus musculus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Mus musculus)
MK2 phosphorylates BRF1 (Mus musculus)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Mus musculus)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Mus musculus)
Protein Kinase B (AKT) phosphorylates KSRP (Mus musculus)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Mus musculus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Mus musculus)
ADP [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
Synthesis of substrates in N-glycan biosythesis (Mus musculus)
GDP-fucose biosynthesis (Mus musculus)
FUK phosphorylates beta-Fuc to Fuc1P (Mus musculus)
ADP [cytosol]
Sialic acid metabolism (Mus musculus)
GNE phosphorylates ManNAc to ManNAc-6-P (Mus musculus)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Mus musculus)
MVD decarboxylates MVA5PP to IPPP (Mus musculus)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Mus musculus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Mus musculus)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Mus musculus)
ER to Golgi Anterograde Transport (Mus musculus)
COPI-mediated anterograde transport (Mus musculus)
GBF1 stimulates ARF nucleotide exchange (Mus musculus)
ADP [cytosol]
COPII-mediated vesicle transport (Mus musculus)
CSNK1D phosphorylates SEC23 (Mus musculus)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Mus musculus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Mus musculus)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Mus musculus)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
FN3K phosphorylates ketosamines (Mus musculus)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Mus musculus)
ADP [cytosol]
Protein folding (Mus musculus)
Chaperonin-mediated protein folding (Mus musculus)
Association of TriC/CCT with target proteins during biosynthesis (Mus musculus)
Association of CCT/TriC with sphingosine kinase 1 (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Mus musculus)
ATP binds G-protein beta associated TRiC/CCT (Mus musculus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Mus musculus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
CK2 phosphorylates PDCL (Mus musculus)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Mus musculus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Mus musculus)
GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Mus musculus)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Mus musculus)
GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Mus musculus)
GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Mus musculus)
GNB5:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Surfactant metabolism (Mus musculus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Mus musculus)
ADP [cytosol]
Translation (Mus musculus)
Eukaryotic Translation Initiation (Mus musculus)
Cap-dependent Translation Initiation (Mus musculus)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Mus musculus)
Cap-bound mRNA is activated by helicases (Mus musculus)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Mus musculus)
Ribosomal scanning (Mus musculus)
ADP [cytosol]
Muscle contraction (Mus musculus)
Cardiac conduction (Mus musculus)
Ion homeostasis (Mus musculus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Mus musculus)
ADP [cytosol]
DMPK phosphorylates PLN (Mus musculus)
ADP [cytosol]
PRKACA phosphorylates PLN (Mus musculus)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Mus musculus)
ADP [cytosol]
Smooth Muscle Contraction (Mus musculus)
ATP Hydrolysis By Myosin (Mus musculus)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Mus musculus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Mus musculus)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Mus musculus)
ADP [cytosol]
Release Of ADP From Myosin (Mus musculus)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Mus musculus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Mus musculus)
ADP [cytosol]
Striated Muscle Contraction (Mus musculus)
ATP Hydrolysis By Myosin (Mus musculus)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Mus musculus)
ADP Bound Myosin Complex [cytosol] (Mus musculus)
ADP [cytosol]
Release Of ADP From Myosin (Mus musculus)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Mus musculus)
ADP Bound Myosin Complex [cytosol] (Mus musculus)
ADP [cytosol]
Neuronal System (Mus musculus)
Transmission across Chemical Synapses (Mus musculus)
Neurotransmitter receptors and postsynaptic signal transmission (Mus musculus)
Activation of NMDA receptors and postsynaptic events (Mus musculus)
Post NMDA receptor activation events (Mus musculus)
Activation of RAC1 downstream of NMDARs (Mus musculus)
CaMKK autophosphorylates in the cytosol (Mus musculus)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Mus musculus)
Trafficking of AMPA receptors (Mus musculus)
Trafficking of GluR1-containing AMPA receptors (Mus musculus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Mus musculus)
Endocytosis of Ca impermeable AMPA receptors (Mus musculus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Mus musculus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Mus musculus)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Mus musculus)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Mus musculus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Mus musculus)
ADP [cytosol]
Programmed Cell Death (Mus musculus)
Apoptosis (Mus musculus)
Caspase activation via extrinsic apoptotic signalling pathway (Mus musculus)
Caspase activation via Dependence Receptors in the absence of ligand (Mus musculus)
Activation of caspase-3 (Mus musculus)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Mus musculus)
Activation of BH3-only proteins (Mus musculus)
Activation of BIM and translocation to mitochondria (Mus musculus)
Phosphorylation of BIM by JNK (Mus musculus)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Mus musculus)
Phosphorylation of DLC2 by MAPK8 (Mus musculus)
ADP [cytosol]
Apoptotic factor-mediated response (Mus musculus)
Cytochrome c-mediated apoptotic response (Mus musculus)
Activation of caspases through apoptosome-mediated cleavage (Mus musculus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Mus musculus)
ADP [cytosol]
Formation of apoptosome (Mus musculus)
CYCS binds to APAF1 (Mus musculus)
ADP [cytosol]
APAF1:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Mus musculus)
ADP [cytosol]
Regulation of the apoptosome activity (Mus musculus)
APAF1 binds AVEN (Mus musculus)
APAF1:ADP [cytosol] (Mus musculus)
ADP [cytosol]
APAF1:AVEN [cytosol] (Mus musculus)
APAF1:ADP [cytosol] (Mus musculus)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Mus musculus)
ADP [cytosol]
Regulated Necrosis (Mus musculus)
RIPK1-mediated regulated necrosis (Mus musculus)
RIPK1 is phosphorylated (Mus musculus)
ADP [cytosol]
RIPK3 is phosphorylated (Mus musculus)
ADP [cytosol]
RIPK3 phosphorylates MLKL (Mus musculus)
ADP [cytosol]
Protein localization (Mus musculus)
Peroxisomal protein import (Mus musculus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Mus musculus)
ADP [cytosol]
Sensory Perception (Mus musculus)
Visual phototransduction (Mus musculus)
The canonical retinoid cycle in rods (twilight vision) (Mus musculus)
ABCA4 mediates atRAL transport (Mus musculus)
ADP [cytosol]
The phototransduction cascade (Mus musculus)
Inactivation, recovery and regulation of the phototransduction cascade (Mus musculus)
GRK1,4,7 phosphorylate MII to p-MII (Mus musculus)
ADP [cytosol]
Signal Transduction (Mus musculus)
Death Receptor Signaling (Mus musculus)
TNF signaling (Mus musculus)
Regulation of TNFR1 signaling (Mus musculus)
CHUK, IKBKB phosphorylate CYLD at S418 (Mus musculus)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Mus musculus)
ADP [cytosol]
MAPKAPK2 phosphorylates RIPK1 at S320 (Mus musculus)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Mus musculus)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Mus musculus)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Mus musculus)
Cell death signalling via NRAGE, NRIF and NADE (Mus musculus)
NRAGE signals death through JNK (Mus musculus)
GTP-bound RAC contributes to JNK activation (Mus musculus)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Mus musculus)
ADP [cytosol]
p75NTR signals via NF-kB (Mus musculus)
NF-kB is activated and signals survival (Mus musculus)
IKKbeta is activated (Mus musculus)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Mus musculus)
ADP [cytosol]
Integrin signaling (Mus musculus)
Autophosphorylation of PTK2 at Y397 (Mus musculus)
ADP [cytosol]
Autophosphorylation of SRC (Mus musculus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Mus musculus)
ADP [cytosol]
SYK activation by SRC (Mus musculus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Mus musculus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Mus musculus)
ADP [cytosol]
Intracellular signaling by second messengers (Mus musculus)
DAG and IP3 signaling (Mus musculus)
CaM pathway (Mus musculus)
Calmodulin induced events (Mus musculus)
PKC phosphorylates GRK2 (Mus musculus)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Mus musculus)
ADP [cytosol]
PIP3 activates AKT signaling (Mus musculus)
AKT phosphorylates targets in the cytosol (Mus musculus)
AKT phosphorylates AKT1S1 (PRAS40) (Mus musculus)
ADP [cytosol]
AKT phosphorylates IKKalpha (Mus musculus)
ADP [cytosol]
AKT phosphorylates MDM2 (Mus musculus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Mus musculus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Mus musculus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Mus musculus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Mus musculus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Mus musculus)
ADP [cytosol]
MAPKs phosphorylate PP2A (Mus musculus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Mus musculus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Mus musculus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Mus musculus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
PTEN Regulation (Mus musculus)
Regulation of PTEN gene transcription (Mus musculus)
mTORC1 phosphorylates MAF1 (Mus musculus)
ADP [cytosol]
Regulation of PTEN stability and activity (Mus musculus)
AKT phosphorylates MKRN1 (Mus musculus)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Mus musculus)
ADP [cytosol]
FRK phosphorylates PTEN (Mus musculus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Mus musculus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Mus musculus)
ADP [cytosol]
MAPK family signaling cascades (Mus musculus)
MAPK1/MAPK3 signaling (Mus musculus)
RAF-independent MAPK1/3 activation (Mus musculus)
MAPK1 (ERK2) activation (Mus musculus)
MAP2K2 phosphorylates MAPK1 (Mus musculus)
ADP [cytosol]
MAPK3 (ERK1) activation (Mus musculus)
Inactivation of MAP2K1 by CDK1 (Mus musculus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Mus musculus)
ADP [cytosol]
RAF/MAP kinase cascade (Mus musculus)
MAP2K and MAPK activation (Mus musculus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Mus musculus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Mus musculus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Mus musculus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Mus musculus)
ADP [cytosol]
Negative regulation of MAPK pathway (Mus musculus)
MAPK12 phosphorylates PTPN3 (Mus musculus)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Mus musculus)
Activated MAPK phosphorylates RAF1 (Mus musculus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Mus musculus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Mus musculus)
ADP [cytosol]
RAF activation (Mus musculus)
MARK3 phosphorylates KSR1 (Mus musculus)
ADP [cytosol]
Phosphorylation of RAF (Mus musculus)
ADP [cytosol]
RAS processing (Mus musculus)
KRAS4B is phosphorylated on serine 181 (Mus musculus)
ADP [cytosol]
MAPK6/MAPK4 signaling (Mus musculus)
Autophosphorylation of PAK1,2,3 (Mus musculus)
ADP [cytosol]
MAPKAPK5 phosphorylates KALRN (Mus musculus)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Mus musculus)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Mus musculus)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Mus musculus)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Mus musculus)
ADP [cytosol]
MTOR signalling (Mus musculus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Mus musculus)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Mus musculus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Mus musculus)
Phosphorylation of TSC2 by PKB (Mus musculus)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Mus musculus)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Mus musculus)
ADP [cytosol]
mTORC1-mediated signalling (Mus musculus)
Phosphorylation and activation of eIF4B by activated S6K1 (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Mus musculus)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Mus musculus)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Mus musculus)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)
ADP [cytosol]
Signaling by Erythropoietin (Mus musculus)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Mus musculus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Mus musculus)
ADP [cytosol]
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Mus musculus)
ADP [cytosol]
Opioid Signalling (Mus musculus)
DARPP-32 events (Mus musculus)
PKA phosphorylates DARPP-32 on Thr34 (Mus musculus)
ADP [cytosol]
PKA phosphorylates PDE4B (Mus musculus)
ADP [cytosol]
G-protein mediated events (Mus musculus)
PLC beta mediated events (Mus musculus)
Ca-dependent events (Mus musculus)
CaM pathway (Mus musculus)
Calmodulin induced events (Mus musculus)
PKC phosphorylates GRK2 (Mus musculus)
ADP [cytosol]
phospho-PLA2 pathway (Mus musculus)
Phosphorylation of cPLA2 by ERK-2 (Mus musculus)
ADP [cytosol]
G alpha (q) signalling events (Mus musculus)
Effects of PIP2 hydrolysis (Mus musculus)
DAG kinase produces phosphatidic acid from DAG (Mus musculus)
ADP [cytosol]
G alpha (s) signalling events (Mus musculus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Mus musculus)
ADP [cytosol]
G-protein beta:gamma signalling (Mus musculus)
G beta:gamma signalling through PI3Kgamma (Mus musculus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Signaling by Hedgehog (Mus musculus)
Hedgehog 'off' state (Mus musculus)
GLI3 is processed to GLI3R by the proteasome (Mus musculus)
CK1 phosphorylates p-GLI3 (Mus musculus)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Mus musculus)
ADP [cytosol]
PKA phosphorylates GLI3 (Mus musculus)
ADP [cytosol]
Hedgehog ligand biogenesis (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)
ADP [cytosol]
Signaling by Hippo (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Mus musculus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Mus musculus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Mus musculus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Mus musculus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Mus musculus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Mus musculus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Mus musculus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Mus musculus)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Mus musculus)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Mus musculus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Mus musculus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Mus musculus)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Mus musculus)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Mus musculus)
ADP [cytosol]
Signaling by NOTCH (Mus musculus)
Signaling by NOTCH3 (Mus musculus)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Mus musculus)
EGFR phosphorylates NOTCH3 (Mus musculus)
ADP [cytosol]
Signaling by NOTCH4 (Mus musculus)
Negative regulation of NOTCH4 signaling (Mus musculus)
AKT1 phosphorylates NOTCH4 (Mus musculus)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Mus musculus)
Signaling by PTK6 (Mus musculus)
ERBB2 Activates PTK6 Signaling (Mus musculus)
ERBB2 promotes PTK6 autophosphorylation (Mus musculus)
ADP [cytosol]
PTK6 Activates STAT3 (Mus musculus)
PTK6 phosphorylates STAP2 (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
PTK6 Down-Regulation (Mus musculus)
SRMS phosphorylates PTK6 (Mus musculus)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Mus musculus)
PTK6 phosphorylates CDKN1B (Mus musculus)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Mus musculus)
PTK6 phosphorylates ARHGAP35 (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates PXN (Mus musculus)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Mus musculus)
PTK6 phosphorylates AKT1 (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates ARAP1 (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates CBL (Mus musculus)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Mus musculus)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Mus musculus)
EGFR phosphorylates GPNMB (Mus musculus)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Mus musculus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Mus musculus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Mus musculus)
ADP [cytosol]
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
ESR-associated SRC autophosphorylates (Mus musculus)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Mus musculus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Mus musculus)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Mus musculus)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by ALK (Mus musculus)
ALK autophosphorylation (Mus musculus)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Mus musculus)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Mus musculus)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Mus musculus)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Mus musculus)
ADP [cytosol]
Signaling by EGFR (Mus musculus)
EGFR autophosphorylation (Mus musculus)
ADP [cytosol]
EGFR downregulation (Mus musculus)
EGFR phosphorylates EPS15 (Mus musculus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Mus musculus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Mus musculus)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Mus musculus)
EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)
ADP [cytosol]
GAB1 signalosome (Mus musculus)
GAB1 phosphorylation by EGFR kinase (Mus musculus)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Mus musculus)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Mus musculus)
ADP [cytosol]
SHC1 events in EGFR signaling (Mus musculus)
SHC1 phosphorylation by phosphorylated EGFR (Mus musculus)
ADP [cytosol]
Signaling by ERBB2 (Mus musculus)
Downregulation of ERBB2 signaling (Mus musculus)
Downregulation of ERBB2:ERBB3 signaling (Mus musculus)
Phosphorylation of USP8 by P-AKT (Mus musculus)
ADP [cytosol]
ERBB2 Activates PTK6 Signaling (Mus musculus)
ERBB2 promotes PTK6 autophosphorylation (Mus musculus)
ADP [cytosol]
PI3K events in ERBB2 signaling (Mus musculus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Mus musculus)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Mus musculus)
Activated PKC phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Mus musculus)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Mus musculus)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Mus musculus)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Mus musculus)
ADP [cytosol]
Signaling by ERBB4 (Mus musculus)
PI3K events in ERBB4 signaling (Mus musculus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Mus musculus)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Mus musculus)
Phosphorylation of SHC1 by ERBB4 homodimers (Mus musculus)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Mus musculus)
ADP [cytosol]
Signaling by FGFR (Mus musculus)
Signaling by FGFR1 (Mus musculus)
Downstream signaling of activated FGFR1 (Mus musculus)
FRS-mediated FGFR1 signaling (Mus musculus)
Activated FGFR1 phosphorylates FRS2 (Mus musculus)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Mus musculus)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Mus musculus)
ADP [cytosol]
PI-3K cascade:FGFR1 (Mus musculus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Mus musculus)
Activated FGFR1 phosphorylates PLCG1 (Mus musculus)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Mus musculus)
Activated FGFR1 phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
FGFR1 ligand binding and activation (Mus musculus)
FGFR1b ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR1b (Mus musculus)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Mus musculus)
ADP [cytosol]
FGFR1c ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR1c (Mus musculus)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Mus musculus)
ADP [cytosol]
Spry regulation of FGF signaling (Mus musculus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Mus musculus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Mus musculus)
ADP [cytosol]
Signaling by FGFR2 (Mus musculus)
Downstream signaling of activated FGFR2 (Mus musculus)
FRS-mediated FGFR2 signaling (Mus musculus)
Activated FGFR2 phosphorylates FRS2 (Mus musculus)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Mus musculus)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Mus musculus)
ADP [cytosol]
PI-3K cascade:FGFR2 (Mus musculus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Mus musculus)
Activated FGFR2 phosphorylates PLCG1 (Mus musculus)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Mus musculus)
Activated FGFR2 phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
FGFR2 ligand binding and activation (Mus musculus)
FGFR2b ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR2b (Mus musculus)
ADP [cytosol]
FGFR2c ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR2c (Mus musculus)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Mus musculus)
ADP [cytosol]
Spry regulation of FGF signaling (Mus musculus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Mus musculus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Mus musculus)
ADP [cytosol]
Signaling by FGFR3 (Mus musculus)
Downstream signaling of activated FGFR3 (Mus musculus)
FRS-mediated FGFR3 signaling (Mus musculus)
Activated FGFR3 phosphorylates FRS2 (Mus musculus)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Mus musculus)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Mus musculus)
ADP [cytosol]
PI-3K cascade:FGFR3 (Mus musculus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Mus musculus)
Activated FGFR3 phosphorylates PLCG1 (Mus musculus)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Mus musculus)
Activated FGFR3 phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
FGFR3 ligand binding and activation (Mus musculus)
FGFR3b ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR3b (Mus musculus)
ADP [cytosol]
FGFR3c ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR3c (Mus musculus)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Mus musculus)
ADP [cytosol]
Spry regulation of FGF signaling (Mus musculus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Mus musculus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Mus musculus)
ADP [cytosol]
Signaling by FGFR4 (Mus musculus)
Downstream signaling of activated FGFR4 (Mus musculus)
FRS-mediated FGFR4 signaling (Mus musculus)
Activated FGFR4 phosphorylates FRS2 (Mus musculus)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Mus musculus)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Mus musculus)
ADP [cytosol]
PI-3K cascade:FGFR4 (Mus musculus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Mus musculus)
Activated FGFR4 phosphorylates PLCG1 (Mus musculus)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Mus musculus)
Activated FGFR4 phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
FGFR4 ligand binding and activation (Mus musculus)
Autocatalytic phosphorylation of FGFR4 (Mus musculus)
ADP [cytosol]
betaKlotho-mediated ligand binding (Mus musculus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Mus musculus)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Mus musculus)
ADP [cytosol]
Spry regulation of FGF signaling (Mus musculus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Mus musculus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Mus musculus)
ADP [cytosol]
Signaling by Insulin receptor (Mus musculus)
Autophosphorylation of insulin receptor (Mus musculus)
ADP [cytosol]
Insulin receptor signalling cascade (Mus musculus)
IRS activation (Mus musculus)
Phosphorylation of IRS (Mus musculus)
ADP [cytosol]
IRS-mediated signalling (Mus musculus)
PI3K Cascade (Mus musculus)
Activation of AKT2 (Mus musculus)
PDPK1 phosphorylates AKT2 (Mus musculus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phosphorylation of SHC1 (Mus musculus)
ADP [cytosol]
Signal attenuation (Mus musculus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Mus musculus)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Mus musculus)
ADP [cytosol]
Signaling by LTK (Mus musculus)
Active LTK phosphorylates IRS1 (Mus musculus)
ADP [cytosol]
Active LTK receptor phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
Autophosphorylation of LTK dimer:ALKAL1,2 (Mus musculus)
ADP [cytosol]
Signaling by MET (Mus musculus)
MET Receptor Activation (Mus musculus)
MET dimers autophosphorylate (Mus musculus)
ADP [cytosol]
MET activates PI3K/AKT signaling (Mus musculus)
MET bound PI3K generates PIP3 (Mus musculus)
ADP [cytosol]
MET phosphorylates GAB1 (Mus musculus)
ADP [cytosol]
MET activates RAS signaling (Mus musculus)
MET phosphorylates SHC1-2 (Mus musculus)
ADP [cytosol]
MET activates STAT3 (Mus musculus)
MET phosphorylates STAT3 (Mus musculus)
ADP [cytosol]
MET promotes cell motility (Mus musculus)
MET activates PTK2 signaling (Mus musculus)
MET phosphorylates PTK2 (Mus musculus)
ADP [cytosol]
PTK2 autophosphorylates (Mus musculus)
ADP [cytosol]
SRC phosphorylates PTK2 (Mus musculus)
ADP [cytosol]
Negative regulation of MET activity (Mus musculus)
MET phosphorylates CBL (Mus musculus)
ADP [cytosol]
Signaling by MST1 (Mus musculus)
MST1R autophosphorylates (Mus musculus)
ADP [cytosol]
Signaling by NTRKs (Mus musculus)
Signaling by NTRK1 (TRKA) (Mus musculus)
PI3K/AKT activation (Mus musculus)
PI3K produces PIP3 and other phosphatidyl inositides (Mus musculus)
ADP [cytosol]
Signalling to ERKs (Mus musculus)
Prolonged ERK activation events (Mus musculus)
ARMS-mediated activation (Mus musculus)
ARMS is phosphorylated by active TrkA receptor (Mus musculus)
ADP [cytosol]
Frs2-mediated activation (Mus musculus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Mus musculus)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Mus musculus)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Mus musculus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Mus musculus)
ADP [cytosol]
Signalling to RAS (Mus musculus)
p38MAPK events (Mus musculus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Mus musculus)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Mus musculus)
Activated NTRK3 signals through PI3K (Mus musculus)
Activated NTRK3 promotes SRC autophosphorylation (Mus musculus)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Mus musculus)
NTRK3 dimers trans-autophosphorylate (Mus musculus)
ADP [cytosol]
Signaling by PDGF (Mus musculus)
Autophosphorylation of PDGF alpha receptors (Mus musculus)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Mus musculus)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Mus musculus)
ADP [cytosol]
Downstream signal transduction (Mus musculus)
Activation of Src (Mus musculus)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Mus musculus)
ADP [cytosol]
Signaling by SCF-KIT (Mus musculus)
Autophosphorylation of KIT (Mus musculus)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Mus musculus)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Mus musculus)
ADP [cytosol]
Phosphorylation of JAK2 (Mus musculus)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Mus musculus)
ADP [cytosol]
Phosphorylation of STATs (Mus musculus)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Mus musculus)
ADP [cytosol]
Regulation of KIT signaling (Mus musculus)
PKC alpha interacts with and phosphorylates KIT (Mus musculus)
ADP [cytosol]
Phosphorylation of APS (Mus musculus)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Mus musculus)
IGF1,2:IGF1R autophosphorylates (Mus musculus)
ADP [cytosol]
IGF1R signaling cascade (Mus musculus)
IRS-related events triggered by IGF1R (Mus musculus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Mus musculus)
ADP [cytosol]
IRS-mediated signalling (Mus musculus)
PI3K Cascade (Mus musculus)
Activation of AKT2 (Mus musculus)
PDPK1 phosphorylates AKT2 (Mus musculus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
SHC-related events triggered by IGF1R (Mus musculus)
IGF1R phosphorylates SHC1 (Mus musculus)
ADP [cytosol]
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
AXL autophosphorylates on Y779 and Y821 (Mus musculus)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Mus musculus)
ADP [cytosol]
FYN autophosphorylates (Mus musculus)
ADP [cytosol]
FYN phosphorylates PAK2 (Mus musculus)
ADP [cytosol]
PAK2 autophorylates (Mus musculus)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Mus musculus)
ADP [cytosol]
PTK2 autophosphorylates (Mus musculus)
ADP [cytosol]
Phosphorylation of SRC-1 (Mus musculus)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Mus musculus)
ADP [cytosol]
SRC-1 phosphorylates SHB (Mus musculus)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Mus musculus)
ADP [cytosol]
Src kinases phosphorylate VAV (Mus musculus)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
ADP [cytosol]
VEGFR2 autophosphorylates (Mus musculus)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Mus musculus)
PDK1 phosphorylates PKC (Mus musculus)
ADP [cytosol]
PKC autophosphorylates (Mus musculus)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Mus musculus)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Mus musculus)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Mus musculus)
AKT1 phosphorylates eNOS (Mus musculus)
ADP [cytosol]
PAK1-3 autophosphorylates (Mus musculus)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Mus musculus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Mus musculus)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Mus musculus)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Mus musculus)
ADP [cytosol]
p38 MAPK activation by VEGFR (Mus musculus)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Mus musculus)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
RHOBTB3 ATPase cycle (Mus musculus)
RHOBTB3 hydrolyzes ATP (Mus musculus)
RHOBTB3:ADP [trans-Golgi network membrane] (Mus musculus)
ADP [cytosol]
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate Formins (Mus musculus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Mus musculus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Mus musculus)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Mus musculus)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Mus musculus)
ADP [cytosol]
PKC phosphorylates NCF1 (Mus musculus)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Mus musculus)
ABL phosphorylates WAVEs (Mus musculus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Mus musculus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Mus musculus)
Actin:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Detachment of WASP/WAVE (Mus musculus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Mus musculus)
Actin:ADP [cytosol] (Mus musculus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Mus musculus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Mus musculus)
ADP [cytosol]
RHO GTPases activate PAKs (Mus musculus)
Autophosphorylation of PAK1,2,3 (Mus musculus)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Mus musculus)
ADP [cytosol]
PAK1 phosphorylates FLNA (Mus musculus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Mus musculus)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Mus musculus)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Mus musculus)
ADP [cytosol]
RHO GTPases activate PKNs (Mus musculus)
PDPK1 phosphorylates PKN1,2,3 (Mus musculus)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Mus musculus)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Mus musculus)
ADP [cytosol]
Signaling by TGFB family members (Mus musculus)
Signaling by Activin (Mus musculus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Mus musculus)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Mus musculus)
ADP [cytosol]
Signaling by BMP (Mus musculus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Mus musculus)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Mus musculus)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Mus musculus)
TGF-beta receptor signaling activates SMADs (Mus musculus)
Activated type I receptor phosphorylates SMAD2/3 directly (Mus musculus)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Mus musculus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Mus musculus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Mus musculus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Mus musculus)
ADP [cytosol]
Signaling by WNT (Mus musculus)
Beta-catenin independent WNT signaling (Mus musculus)
Ca2+ pathway (Mus musculus)
Activation of NLK (Mus musculus)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Mus musculus)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Mus musculus)
ADP [cytosol]
PCP/CE pathway (Mus musculus)
WNT5A-dependent internalization of FZD4 (Mus musculus)
DVL2 is phosphorylated by PKC (Mus musculus)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Mus musculus)
AXIN is phosphorylated in the destruction complex (Mus musculus)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Mus musculus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Mus musculus)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Mus musculus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Mus musculus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Mus musculus)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Mus musculus)
ADP [cytosol]
TCF dependent signaling in response to WNT (Mus musculus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Mus musculus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Mus musculus)
ADP [cytosol]
WNT mediated activation of DVL (Mus musculus)
CSNK2-mediated phosphorylation of DVL (Mus musculus)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Mus musculus)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Mus musculus)
ADP [cytosol]
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
ABC transporters in lipid homeostasis (Mus musculus)
ABCA12 transports lipids from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Mus musculus)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Mus musculus)
ADP [cytosol]
ABCA7:Apo1A-mediated phospholipid efflux (Mus musculus)
ADP [cytosol]
ABCAs mediate lipid efflux (Mus musculus)
ADP [cytosol]
ABCAs mediate lipid influx (Mus musculus)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Mus musculus)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Mus musculus)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCA4 mediates atRAL transport (Mus musculus)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Mus musculus)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Mus musculus)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
HCO3- transport through ion channel (Mus musculus)
ADP [cytosol]
Mitochondrial ABC transporters (Mus musculus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Mus musculus)
ADP [cytosol]
The ABCC family mediates organic anion transport (Mus musculus)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Mus musculus)
ADP [cytosol]
Aquaporin-mediated transport (Mus musculus)
Vasopressin regulates renal water homeostasis via Aquaporins (Mus musculus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Mus musculus)
ADP [cytosol]
Ion channel transport (Mus musculus)
Ion transport by P-type ATPases (Mus musculus)
ATP12A:ATP4B exchanges K+ for H+ (Mus musculus)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Mus musculus)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Mus musculus)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Mus musculus)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Mus musculus)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Mus musculus)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Mus musculus)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Mus musculus)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Mus musculus)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Mus musculus)
ADP [cytosol]
Stimuli-sensing channels (Mus musculus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Mus musculus)
ADP [cytosol]
Iron uptake and transport (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
ADP [cytosol]
Transferrin endocytosis and recycling (Mus musculus)
Acidification of Tf:TfR1 containing endosome (Mus musculus)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Mus musculus)
Plasma lipoprotein assembly (Mus musculus)
HDL assembly (Mus musculus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Mus musculus)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Mus musculus)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Mus musculus)
ADP [cytosol]
Plasma lipoprotein remodeling (Mus musculus)
HDL remodeling (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
ADP [cytosol]
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Mus musculus)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Mus musculus)
ADP [cytosol]
Vesicle-mediated transport (Mus musculus)
Membrane Trafficking (Mus musculus)
Clathrin-mediated endocytosis (Mus musculus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Mus musculus)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Mus musculus)
ADBRK1,2 phosphorylate AVPR2 (Mus musculus)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Mus musculus)
clathrin:HSPA8:ADP [cytosol] (Mus musculus)
HSPA8:ADP [cytosol] (Mus musculus)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Mus musculus)
ADP [cytosol]
ER to Golgi Anterograde Transport (Mus musculus)
COPI-mediated anterograde transport (Mus musculus)
GBF1 stimulates ARF nucleotide exchange (Mus musculus)
ADP [cytosol]
COPII-mediated vesicle transport (Mus musculus)
CSNK1D phosphorylates SEC23 (Mus musculus)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Mus musculus)
ESCRT Disassembly (Mus musculus)
ADP [cytosol]
Gap junction trafficking and regulation (Mus musculus)
Regulation of gap junction activity (Mus musculus)
Phosphorylation of Cx43 by c-src (Mus musculus)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Mus musculus)
Golgi-to-ER retrograde transport (Mus musculus)
COPI-independent Golgi-to-ER retrograde traffic (Mus musculus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Mus musculus)
ADP [cytosol]
Intra-Golgi traffic (Mus musculus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Mus musculus)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Mus musculus)
ATP hydrolysis by RHOBTB3 promotes PLIN3 dissociation (Mus musculus)
RHOBTB3:ADP [trans-Golgi network membrane] (Mus musculus)
ADP [cytosol]
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Mus musculus)
ADP [cytosol]
Rab regulation of trafficking (Mus musculus)
RAB GEFs exchange GTP for GDP on RABs (Mus musculus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Mus musculus)
ADP [cytosol]
p-ULK1 phosphorylates DENND3 (Mus musculus)
ADP [cytosol]
trans-Golgi Network Vesicle Budding (Mus musculus)
Golgi Associated Vesicle Biogenesis (Mus musculus)
trans-Golgi Network Derived Vesicle Uncoating (Mus musculus)
ADP [cytosol]
Lysosome Vesicle Biogenesis (Mus musculus)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Mus musculus)
ADP [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Chorismate via Shikimate Pathway (Mycobacterium tuberculosis)
Phosphorylation of shikimate (Mycobacterium tuberculosis)
ADP [cytosol]
Sulfur compound metabolism (Mycobacterium tuberculosis)
Sulfate assimilation (Mycobacterium tuberculosis)
APS is phosphorylated to PAPS (Mycobacterium tuberculosis)
ADP [cytosol]
sulfate uptake in the cytosol (Mycobacterium tuberculosis)
ADP [cytosol]
Cell Cycle (Plasmodium falciparum)
Cell Cycle, Mitotic (Plasmodium falciparum)
M Phase (Plasmodium falciparum)
Mitotic Prometaphase (Plasmodium falciparum)
Condensation of Prometaphase Chromosomes (Plasmodium falciparum)
CK2 phosphorylates condensin I subunits (Plasmodium falciparum)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Plasmodium falciparum)
PLK1 phosphorylates NUDC (Plasmodium falciparum)
ADP [cytosol]
Mitotic Prophase (Plasmodium falciparum)
Golgi Cisternae Pericentriolar Stack Reorganization (Plasmodium falciparum)
PLK1 phosphorylates GORASP1 (Plasmodium falciparum)
ADP [cytosol]
Cellular responses to stimuli (Plasmodium falciparum)
Cellular responses to stress (Plasmodium falciparum)
Cellular response to heat stress (Plasmodium falciparum)
Regulation of HSF1-mediated heat shock response (Plasmodium falciparum)
HSP110s exchange ATP for ADP on HSP70s:ADP (Plasmodium falciparum)
ADP [cytosol]
HSP70s:ADP [cytosol] (Plasmodium falciparum)
HSP13:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP14:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA2:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA4:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA5:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA6:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA8:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA9:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Plasmodium falciparum)
HSP70s:ADP [cytosol] (Plasmodium falciparum)
HSP13:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP14:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA2:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA4:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA5:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA6:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA8:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSPA9:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Plasmodium falciparum)
ATP binding to HSP90 triggers conformation change (Plasmodium falciparum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
ATP hydrolysis by HSP70 (Plasmodium falciparum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Plasmodium falciparum)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Plasmodium falciparum)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Plasmodium falciparum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Plasmodium falciparum)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Plasmodium falciparum)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Plasmodium falciparum)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
Drug ADME (Plasmodium falciparum)
Azathioprine ADME (Plasmodium falciparum)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Plasmodium falciparum)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Plasmodium falciparum)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Plasmodium falciparum)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Plasmodium falciparum)
ADP [cytosol]
Ciprofloxacin ADME (Plasmodium falciparum)
ABCG2 transports Cipro from hepatic cell to extracellular space (Plasmodium falciparum)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Plasmodium falciparum)
ADP [cytosol]
Paracetamol ADME (Plasmodium falciparum)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)
ADP [cytosol]
Prednisone ADME (Plasmodium falciparum)
ABCB1 transports PREDN,PREDL out of hepatic cells (Plasmodium falciparum)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Plasmodium falciparum)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Plasmodium falciparum)
ADP [cytosol]
Ribavirin ADME (Plasmodium falciparum)
NME1,2 hexamers phosphorylate RBV-DP (Plasmodium falciparum)
ADP [cytosol]
Hemostasis (Plasmodium falciparum)
Platelet activation, signaling and aggregation (Plasmodium falciparum)
Effects of PIP2 hydrolysis (Plasmodium falciparum)
DAG kinase produces phosphatidic acid from DAG (Plasmodium falciparum)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Plasmodium falciparum)
Platelet degranulation (Plasmodium falciparum)
ABCC4 accumulation of dense granule contents (Plasmodium falciparum)
ADP [cytosol]
Immune System (Plasmodium falciparum)
Adaptive Immune System (Plasmodium falciparum)
Signaling by the B Cell Receptor (BCR) (Plasmodium falciparum)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Plasmodium falciparum)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Plasmodium falciparum)
ADP [cytosol]
Metabolism (Plasmodium falciparum)
Aerobic respiration and respiratory electron transport (Plasmodium falciparum)
Pyruvate metabolism (Plasmodium falciparum)
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
ADP [cytosol]
Biological oxidations (Plasmodium falciparum)
Phase II - Conjugation of compounds (Plasmodium falciparum)
Glutathione conjugation (Plasmodium falciparum)
Glutathione synthesis and recycling (Plasmodium falciparum)
GSS:Mg2+ dimer synthesizes GSH (Plasmodium falciparum)
ADP [cytosol]
Inositol phosphate metabolism (Plasmodium falciparum)
Synthesis of IP3 and IP4 in the cytosol (Plasmodium falciparum)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Plasmodium falciparum)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Plasmodium falciparum)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)
ADP [cytosol]
Metabolism of carbohydrates (Plasmodium falciparum)
Glucose metabolism (Plasmodium falciparum)
Gluconeogenesis (Plasmodium falciparum)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Plasmodium falciparum)
ADP [cytosol]
Glycolysis (Plasmodium falciparum)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Plasmodium falciparum)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Plasmodium falciparum)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
ADP [cytosol]
Metabolism of lipids (Plasmodium falciparum)
Fatty acid metabolism (Plasmodium falciparum)
Carnitine metabolism (Plasmodium falciparum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Plasmodium falciparum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Plasmodium falciparum)
ADP [cytosol]
Metabolism of steroids (Plasmodium falciparum)
Bile acid and bile salt metabolism (Plasmodium falciparum)
Recycling of bile acids and salts (Plasmodium falciparum)
ABCB11 transports bile salts from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
Synthesis of bile acids and bile salts (Plasmodium falciparum)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Plasmodium falciparum)
ABCB11 transports bile salts from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
Phospholipid metabolism (Plasmodium falciparum)
Glycerophospholipid biosynthesis (Plasmodium falciparum)
Synthesis of PC (Plasmodium falciparum)
Cho is phosphorylated to PCho by CHK dimer (Plasmodium falciparum)
ADP [cytosol]
Synthesis of PE (Plasmodium falciparum)
ETA is phosphorylated to PETA by CHK/ETNK (Plasmodium falciparum)
ADP [cytosol]
PI Metabolism (Plasmodium falciparum)
Synthesis of PIPs at the Golgi membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Plasmodium falciparum)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Plasmodium falciparum)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Plasmodium falciparum)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Plasmodium falciparum)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Plasmodium falciparum)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
Sphingolipid metabolism (Plasmodium falciparum)
Sphingolipid de novo biosynthesis (Plasmodium falciparum)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Plasmodium falciparum)
ADP [cytosol]
CSNK1G2 phosphorylates p-CERT1-2 (Plasmodium falciparum)
ADP [cytosol]
Triglyceride metabolism (Plasmodium falciparum)
Triglyceride biosynthesis (Plasmodium falciparum)
Conversion of Glycerol to Glycerol-3-phosphate (Plasmodium falciparum)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Plasmodium falciparum)
eNOS activation (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
ADP [cytosol]
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Plasmodium falciparum)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Plasmodium falciparum)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Plasmodium falciparum)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Plasmodium falciparum)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Plasmodium falciparum)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Plasmodium falciparum)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Plasmodium falciparum)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Plasmodium falciparum)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Plasmodium falciparum)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Plasmodium falciparum)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Plasmodium falciparum)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Plasmodium falciparum)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Plasmodium falciparum)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Plasmodium falciparum)
ADP [cytosol]
Nucleotide biosynthesis (Plasmodium falciparum)
Pyrimidine biosynthesis (Plasmodium falciparum)
CAD hexamer transforms L-Gln to CAP (Plasmodium falciparum)
ADP [cytosol]
Metabolism of porphyrins (Plasmodium falciparum)
Heme biosynthesis (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
Heme degradation (Plasmodium falciparum)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of water-soluble vitamins and cofactors (Plasmodium falciparum)
Metabolism of folate and pterines (Plasmodium falciparum)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Plasmodium falciparum)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Plasmodium falciparum)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Plasmodium falciparum)
RFK:Mg2+ phosphorylates RIB (Plasmodium falciparum)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Plasmodium falciparum)
Coenzyme A biosynthesis (Plasmodium falciparum)
DCAKD phosphorylates DP-CoA (Plasmodium falciparum)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Plasmodium falciparum)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Plasmodium falciparum)
2xPDKX:2xZn2+ phosphorylates PDX (Plasmodium falciparum)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Plasmodium falciparum)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Plasmodium falciparum)
ADP [cytosol]
Metabolism of RNA (Plasmodium falciparum)
Nonsense-Mediated Decay (NMD) (Plasmodium falciparum)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Plasmodium falciparum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
ADP [cytosol]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Asparagine N-linked glycosylation (Plasmodium falciparum)
Transport to the Golgi and subsequent modification (Plasmodium falciparum)
ER to Golgi Anterograde Transport (Plasmodium falciparum)
COPI-mediated anterograde transport (Plasmodium falciparum)
GBF1 stimulates ARF nucleotide exchange (Plasmodium falciparum)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Plasmodium falciparum)
TTLLs polyglutamylate tubulin (Plasmodium falciparum)
ADP [cytosol]
Protein folding (Plasmodium falciparum)
Chaperonin-mediated protein folding (Plasmodium falciparum)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Plasmodium falciparum)
ATP binds G-protein beta associated TRiC/CCT (Plasmodium falciparum)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Plasmodium falciparum)
CCT/TRiC:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Plasmodium falciparum)
Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Plasmodium falciparum)
CCT/TRiC:ADP [cytosol] (Plasmodium falciparum)
ADP [cytosol]
Surfactant metabolism (Plasmodium falciparum)
ABCA3 transports PC, PG from ER membrane to lamellar body (Plasmodium falciparum)
ADP [cytosol]
Translation (Plasmodium falciparum)
Eukaryotic Translation Initiation (Plasmodium falciparum)
Cap-dependent Translation Initiation (Plasmodium falciparum)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Plasmodium falciparum)
Cap-bound mRNA is activated by helicases (Plasmodium falciparum)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Plasmodium falciparum)
Ribosomal scanning (Plasmodium falciparum)
ADP [cytosol]
Sensory Perception (Plasmodium falciparum)
Visual phototransduction (Plasmodium falciparum)
The canonical retinoid cycle in rods (twilight vision) (Plasmodium falciparum)
ABCA4 mediates atRAL transport (Plasmodium falciparum)
ADP [cytosol]
Signal Transduction (Plasmodium falciparum)
Intracellular signaling by second messengers (Plasmodium falciparum)
PIP3 activates AKT signaling (Plasmodium falciparum)
Negative regulation of the PI3K/AKT network (Plasmodium falciparum)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Plasmodium falciparum)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
MAPK family signaling cascades (Plasmodium falciparum)
MAPK1/MAPK3 signaling (Plasmodium falciparum)
RAF/MAP kinase cascade (Plasmodium falciparum)
Negative regulation of MAPK pathway (Plasmodium falciparum)
Negative feedback regulation of MAPK pathway (Plasmodium falciparum)
Activated MAPK phosphorylates RAF1 (Plasmodium falciparum)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Plasmodium falciparum)
ADP [cytosol]
RAF activation (Plasmodium falciparum)
MARK3 phosphorylates KSR1 (Plasmodium falciparum)
ADP [cytosol]
MAPK6/MAPK4 signaling (Plasmodium falciparum)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Plasmodium falciparum)
ADP [cytosol]
Signaling by GPCR (Plasmodium falciparum)
GPCR downstream signalling (Plasmodium falciparum)
G alpha (q) signalling events (Plasmodium falciparum)
Effects of PIP2 hydrolysis (Plasmodium falciparum)
DAG kinase produces phosphatidic acid from DAG (Plasmodium falciparum)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by VEGF (Plasmodium falciparum)
VEGFA-VEGFR2 Pathway (Plasmodium falciparum)
VEGFR2 mediated vascular permeability (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Plasmodium falciparum)
Signaling by Rho GTPases (Plasmodium falciparum)
RHO GTPase Effectors (Plasmodium falciparum)
RHO GTPases Activate NADPH Oxidases (Plasmodium falciparum)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Plasmodium falciparum)
ADP [cytosol]
Signaling by WNT (Plasmodium falciparum)
Beta-catenin independent WNT signaling (Plasmodium falciparum)
Ca2+ pathway (Plasmodium falciparum)
Autophosphorylation and activation of CAMK2 (Plasmodium falciparum)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Plasmodium falciparum)
ADP [cytosol]
Transport of small molecules (Plasmodium falciparum)
ABC-family proteins mediated transport (Plasmodium falciparum)
ABC transporters in lipid homeostasis (Plasmodium falciparum)
ABCA12 transports lipids from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Plasmodium falciparum)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Plasmodium falciparum)
ADP [cytosol]
ABCAs mediate lipid efflux (Plasmodium falciparum)
ADP [cytosol]
ABCAs mediate lipid influx (Plasmodium falciparum)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
ABCA4 mediates atRAL transport (Plasmodium falciparum)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Plasmodium falciparum)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
HCO3- transport through ion channel (Plasmodium falciparum)
ADP [cytosol]
Mitochondrial ABC transporters (Plasmodium falciparum)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Plasmodium falciparum)
ADP [cytosol]
The ABCC family mediates organic anion transport (Plasmodium falciparum)
ADP [cytosol]
Ion channel transport (Plasmodium falciparum)
Ion transport by P-type ATPases (Plasmodium falciparum)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Plasmodium falciparum)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Plasmodium falciparum)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Plasmodium falciparum)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Plasmodium falciparum)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Plasmodium falciparum)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Plasmodium falciparum)
ADP [cytosol]
Iron uptake and transport (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
ADP [cytosol]
Transferrin endocytosis and recycling (Plasmodium falciparum)
Acidification of Tf:TfR1 containing endosome (Plasmodium falciparum)
ADP [cytosol]
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Plasmodium falciparum)
ADP [cytosol]
Vesicle-mediated transport (Plasmodium falciparum)
Membrane Trafficking (Plasmodium falciparum)
Clathrin-mediated endocytosis (Plasmodium falciparum)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Plasmodium falciparum)
ADP [cytosol]
ER to Golgi Anterograde Transport (Plasmodium falciparum)
COPI-mediated anterograde transport (Plasmodium falciparum)
GBF1 stimulates ARF nucleotide exchange (Plasmodium falciparum)
ADP [cytosol]
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Rattus norvegicus)
ADP [cytosol]
Selective autophagy (Rattus norvegicus)
Mitophagy (Rattus norvegicus)
Receptor Mediated Mitophagy (Rattus norvegicus)
FUNDC1 is phosphorylated by CK2 (Rattus norvegicus)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Rattus norvegicus)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Rattus norvegicus)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Rattus norvegicus)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Rattus norvegicus)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
ADP [cytosol]
Cell Cycle (Rattus norvegicus)
Cell Cycle Checkpoints (Rattus norvegicus)
G2/M Checkpoints (Rattus norvegicus)
G2/M DNA replication checkpoint (Rattus norvegicus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Rattus norvegicus)
ADP [cytosol]
Cell Cycle, Mitotic (Rattus norvegicus)
M Phase (Rattus norvegicus)
Mitotic Metaphase and Anaphase (Rattus norvegicus)
Mitotic Anaphase (Rattus norvegicus)
Nuclear Envelope (NE) Reassembly (Rattus norvegicus)
Initiation of Nuclear Envelope (NE) Reformation (Rattus norvegicus)
CDK1 phosphorylates LBR (Rattus norvegicus)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Rattus norvegicus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Rattus norvegicus)
ADP [cytosol]
Mitotic Prometaphase (Rattus norvegicus)
Condensation of Prometaphase Chromosomes (Rattus norvegicus)
CK2 phosphorylates condensin I subunits (Rattus norvegicus)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Rattus norvegicus)
PLK1 phosphorylates NUDC (Rattus norvegicus)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Rattus norvegicus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Rattus norvegicus)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Rattus norvegicus)
ADP [cytosol]
Mitotic Prophase (Rattus norvegicus)
Golgi Cisternae Pericentriolar Stack Reorganization (Rattus norvegicus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Rattus norvegicus)
ADP [cytosol]
Nuclear Envelope Breakdown (Rattus norvegicus)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Rattus norvegicus)
CDK1:CCNB phosphorylates NEK9 (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Rattus norvegicus)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Rattus norvegicus)
CDK1 phosphorylates NUP98 (Rattus norvegicus)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Rattus norvegicus)
G1 Phase (Rattus norvegicus)
Cyclin D associated events in G1 (Rattus norvegicus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Rattus norvegicus)
ADP [cytosol]
G1/S Transition (Rattus norvegicus)
Cyclin E associated events during G1/S transition (Rattus norvegicus)
AKT phosphorylates p21Cip1 and p27Kip1 (Rattus norvegicus)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
PTK6 phosphorylates CDKN1B (Rattus norvegicus)
ADP [cytosol]
Mitotic G2-G2/M phases (Rattus norvegicus)
G2/M Transition (Rattus norvegicus)
AURKA Activation by TPX2 (Rattus norvegicus)
TPX2 promotes AURKA autophosphorylation (Rattus norvegicus)
ADP [cytosol]
Centrosome maturation (Rattus norvegicus)
Loss of proteins required for interphase microtubule organization from the centrosome (Rattus norvegicus)
Loss of Nlp from mitotic centrosomes (Rattus norvegicus)
Plk1-mediated phosphorylation of Nlp (Rattus norvegicus)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Rattus norvegicus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Rattus norvegicus)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Rattus norvegicus)
AURKA phosphorylates PHLDA1 (Rattus norvegicus)
ADP [cytosol]
Polo-like kinase mediated events (Rattus norvegicus)
Activation of Cdc25C (Rattus norvegicus)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Rattus norvegicus)
AJUBA facilitates AURKA autophosphorylation (Rattus norvegicus)
ADP [cytosol]
AURKA phosphorylates PLK1 (Rattus norvegicus)
ADP [cytosol]
CDK1 phosphorylates BORA (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates BORA (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates OPTN (Rattus norvegicus)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Rattus norvegicus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Rattus norvegicus)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Rattus norvegicus)
ADP [cytosol]
S Phase (Rattus norvegicus)
Cyclin A:Cdk2-associated events at S phase entry (Rattus norvegicus)
AKT phosphorylates p21Cip1 and p27Kip1 (Rattus norvegicus)
ADP [cytosol]
SCF(Skp2)-mediated degradation of p27/p21 (Rattus norvegicus)
PTK6 phosphorylates CDKN1B (Rattus norvegicus)
ADP [cytosol]
Cell-Cell communication (Rattus norvegicus)
Nephrin family interactions (Rattus norvegicus)
Phosphorylation of nephrin by FYN (Rattus norvegicus)
ADP [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular Senescence (Rattus norvegicus)
Oxidative Stress Induced Senescence (Rattus norvegicus)
MAP3K5 phosphorylates MKK3 and MKK6 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Cellular response to chemical stress (Rattus norvegicus)
KEAP1-NFE2L2 pathway (Rattus norvegicus)
Nuclear events mediated by NFE2L2 (Rattus norvegicus)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Rattus norvegicus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Rattus norvegicus)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Rattus norvegicus)
ADP [cytosol]
Cellular response to heat stress (Rattus norvegicus)
Regulation of HSF1-mediated heat shock response (Rattus norvegicus)
Constitutive phosphorylation by pERK1/2 (Rattus norvegicus)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Rattus norvegicus)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Rattus norvegicus)
ADP [cytosol]
HSP70s:ADP [cytosol] (Rattus norvegicus)
HSP13:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP14:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Rattus norvegicus)
HSP70s:ADP [cytosol] (Rattus norvegicus)
HSP13:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP14:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA2:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA4:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA5:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA8:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSPA9:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Rattus norvegicus)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Rattus norvegicus)
ATP binding to HSP90 triggers conformation change (Rattus norvegicus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
ATP hydrolysis by HSP70 (Rattus norvegicus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Rattus norvegicus)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Rattus norvegicus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Rattus norvegicus)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Rattus norvegicus)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Unfolded Protein Response (UPR) (Rattus norvegicus)
IRE1alpha activates chaperones (Rattus norvegicus)
IRE1 dimer autophosphorylates (Rattus norvegicus)
ADP [cytosol]
PERK regulates gene expression (Rattus norvegicus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Rattus norvegicus)
ADP [cytosol]
DNA Replication (Rattus norvegicus)
DNA Replication Pre-Initiation (Rattus norvegicus)
Assembly of the pre-replicative complex (Rattus norvegicus)
Assembly of the ORC complex at the origin of replication (Rattus norvegicus)
ORC6 is phosphorylated on T195 (Rattus norvegicus)
ADP [cytosol]
Developmental Biology (Rattus norvegicus)
MITF-M-regulated melanocyte development (Rattus norvegicus)
Transcriptional and post-translational regulation of MITF-M expression and activity (Rattus norvegicus)
MAPK-dependent phosphorylation of KARS (Rattus norvegicus)
ADP [cytosol]
Nervous system development (Rattus norvegicus)
Axon guidance (Rattus norvegicus)
EPH-Ephrin signaling (Rattus norvegicus)
EPH receptors autophosphorylate (Rattus norvegicus)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Rattus norvegicus)
SFKs phosphorylate VAV2,3 (Rattus norvegicus)
ADP [cytosol]
EPHB-mediated forward signaling (Rattus norvegicus)
EPHB phosphorylates TIAM1 (Rattus norvegicus)
ADP [cytosol]
PAK1 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Rattus norvegicus)
ADP [cytosol]
Ephrin signaling (Rattus norvegicus)
PAKs autophosphorylate (Rattus norvegicus)
ADP [cytosol]
PAKs phosphorylate MLC (Rattus norvegicus)
ADP [cytosol]
L1CAM interactions (Rattus norvegicus)
Recycling pathway of L1 (Rattus norvegicus)
Phosphorylation of L1 by ERK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of L1 by SRC (Rattus norvegicus)
ADP [cytosol]
Signal transduction by L1 (Rattus norvegicus)
Interaction of PAK1 with Rac1-GTP (Rattus norvegicus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Rattus norvegicus)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of L1 by CK-II (Rattus norvegicus)
ADP [cytosol]
Netrin-1 signaling (Rattus norvegicus)
DCC mediated attractive signaling (Rattus norvegicus)
Phosphorylation of DCC by Fyn (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and activation of Ezrin (Rattus norvegicus)
ADP [cytosol]
RET signaling (Rattus norvegicus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Rattus norvegicus)
ADP [cytosol]
RET tyrosine phosphorylation (Rattus norvegicus)
ADP [cytosol]
Reelin signalling pathway (Rattus norvegicus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Rattus norvegicus)
ADP [cytosol]
Semaphorin interactions (Rattus norvegicus)
CRMPs in Sema3A signaling (Rattus norvegicus)
Phosphorylation of CRMPs by Cdk5 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Rattus norvegicus)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Rattus norvegicus)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Rattus norvegicus)
Autophosphorylation of PAK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Rattus norvegicus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Rattus norvegicus)
ADP [cytosol]
Sema4D in semaphorin signaling (Rattus norvegicus)
Sema4D induced cell migration and growth-cone collapse (Rattus norvegicus)
SEMA4D interacts with Plexin-B1:ErbB2 (Rattus norvegicus)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Rattus norvegicus)
SEMA4D interacts with Plexin-B1:Met (Rattus norvegicus)
ADP [cytosol]
Drug ADME (Rattus norvegicus)
Aspirin ADME (Rattus norvegicus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Rattus norvegicus)
ADP [cytosol]
Azathioprine ADME (Rattus norvegicus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Rattus norvegicus)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Rattus norvegicus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Rattus norvegicus)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Rattus norvegicus)
ADP [cytosol]
Ciprofloxacin ADME (Rattus norvegicus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Rattus norvegicus)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Rattus norvegicus)
ADP [cytosol]
Paracetamol ADME (Rattus norvegicus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)
ADP [cytosol]
Prednisone ADME (Rattus norvegicus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Rattus norvegicus)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Rattus norvegicus)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Rattus norvegicus)
ADP [cytosol]
Ribavirin ADME (Rattus norvegicus)
ADK phosphorylates RBV (Rattus norvegicus)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Rattus norvegicus)
ADP [cytosol]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
Regulation of TP53 Activity (Rattus norvegicus)
Regulation of TP53 Expression and Degradation (Rattus norvegicus)
Regulation of TP53 Degradation (Rattus norvegicus)
AKT phosphorylates MDM2 (Rattus norvegicus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Rattus norvegicus)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Rattus norvegicus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Rattus norvegicus)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Rattus norvegicus)
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Rattus norvegicus)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Rattus norvegicus)
PLK2 phosphorylates CENPJ (Rattus norvegicus)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Rattus norvegicus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Rattus norvegicus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Rattus norvegicus)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Rattus norvegicus)
Regulation of RUNX3 expression and activity (Rattus norvegicus)
SRC phosphorylates RUNX3 (Rattus norvegicus)
ADP [cytosol]
Hemostasis (Rattus norvegicus)
Cell surface interactions at the vascular wall (Rattus norvegicus)
PECAM1 interactions (Rattus norvegicus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Rattus norvegicus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Rattus norvegicus)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Rattus norvegicus)
ADP [cytosol]
Kinesins (Rattus norvegicus)
Kinesins move along microtubules consuming ATP (Rattus norvegicus)
ADP [cytosol]
Platelet activation, signaling and aggregation (Rattus norvegicus)
Effects of PIP2 hydrolysis (Rattus norvegicus)
DAG kinase produces phosphatidic acid from DAG (Rattus norvegicus)
ADP [cytosol]
GPVI-mediated activation cascade (Rattus norvegicus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Rattus norvegicus)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
SYK autophosphorylates (Rattus norvegicus)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Rattus norvegicus)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Rattus norvegicus)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Rattus norvegicus)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Rattus norvegicus)
Integrin signaling (Rattus norvegicus)
Autophosphorylation of PTK2 at Y397 (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of SRC (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Rattus norvegicus)
ADP [cytosol]
SYK activation by SRC (Rattus norvegicus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Rattus norvegicus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Rattus norvegicus)
Disinhibition of SNARE formation (Rattus norvegicus)
Phosphorylation of Platelet Sec-1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Rattus norvegicus)
ADP [cytosol]
Platelet degranulation (Rattus norvegicus)
ABCC4 accumulation of dense granule contents (Rattus norvegicus)
ADP [cytosol]
Signal amplification (Rattus norvegicus)
ADP signalling through P2Y purinoceptor 1 (Rattus norvegicus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Rattus norvegicus)
ADP [cytosol]
Platelet homeostasis (Rattus norvegicus)
Platelet sensitization by LDL (Rattus norvegicus)
FGR binds and phosphorylates LRP8 (Rattus norvegicus)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Rattus norvegicus)
ADP [cytosol]
PECAM1 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Rattus norvegicus)
ADP [cytosol]
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Rattus norvegicus)
Transport of Antigen peptide in to ER (Rattus norvegicus)
ADP [cytosol]
Costimulation by the CD28 family (Rattus norvegicus)
CD28 co-stimulation (Rattus norvegicus)
CD28 dependent PI3K/Akt signaling (Rattus norvegicus)
AKT interacts and phosphorylates Cot (Rattus norvegicus)
ADP [cytosol]
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Rattus norvegicus)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Rattus norvegicus)
ADP [cytosol]
CD28 dependent Vav1 pathway (Rattus norvegicus)
Activation of Vav1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CD28 (Rattus norvegicus)
ADP [cytosol]
CTLA4 inhibitory signaling (Rattus norvegicus)
Phosphorylation of CTLA-4 (Rattus norvegicus)
ADP [cytosol]
PD-1 signaling (Rattus norvegicus)
Phosphorylation of PD-1 (Rattus norvegicus)
ADP [cytosol]
MHC class II antigen presentation (Rattus norvegicus)
Transport of antigen loaded MHC II molecules to surface (Rattus norvegicus)
ADP [cytosol]
Rap1 signalling (Rattus norvegicus)
PKA/PKG phosphorylate Rap1GAP2 (Rattus norvegicus)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Rattus norvegicus)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Rattus norvegicus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Rattus norvegicus)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Rattus norvegicus)
ADP [cytosol]
CD22 mediated BCR regulation (Rattus norvegicus)
LYN phosphorylates CD22 (Rattus norvegicus)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Rattus norvegicus)
Activation of NF-kappaB in B cells (Rattus norvegicus)
Activated IKK phosphorylates I-kappaB (Rattus norvegicus)
ADP [cytosol]
PRKCB (PKC-beta) phosphorylates CARMA1 (Rattus norvegicus)
ADP [cytosol]
TCR signaling (Rattus norvegicus)
Downstream TCR signaling (Rattus norvegicus)
Activation of IKK complex (Rattus norvegicus)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Rattus norvegicus)
ADP [cytosol]
Change of PKC theta conformation (Rattus norvegicus)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of Bcl10 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CARMA1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of PKC theta (Rattus norvegicus)
ADP [cytosol]
Generation of second messenger molecules (Rattus norvegicus)
Phosphorylation of PLC-gamma1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SLP-76 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Rattus norvegicus)
Activation of Lck (Rattus norvegicus)
ADP [cytosol]
Inactivation of Lck by Csk (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Rattus norvegicus)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Rattus norvegicus)
Activation of ZAP-70 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Rattus norvegicus)
ADP [cytosol]
Cytokine Signaling in Immune system (Rattus norvegicus)
Growth hormone receptor signaling (Rattus norvegicus)
JAK2 phosphorylation (Rattus norvegicus)
ADP [cytosol]
JAK2 phosphorylation of GHR (Rattus norvegicus)
ADP [cytosol]
Lyn activates ERK (Rattus norvegicus)
ADP [cytosol]
Interferon Signaling (Rattus norvegicus)
Antiviral mechanism by IFN-stimulated genes (Rattus norvegicus)
PKR-mediated signaling (Rattus norvegicus)
p-PKR dimer phosphorylates CDK1 (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates MAPT (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Rattus norvegicus)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Rattus norvegicus)
ADP [cytosol]
Interferon alpha/beta signaling (Rattus norvegicus)
Activation of JAK kinases (Rattus norvegicus)
ADP [cytosol]
Formation of p-STAT1 homodimer (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STAT2 (Rattus norvegicus)
ADP [cytosol]
Interferon gamma signaling (Rattus norvegicus)
IFNG signaling activates MAPKs (Rattus norvegicus)
JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of JAK2 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Rattus norvegicus)
ADP [cytosol]
Transphosphorylation of JAK1 (Rattus norvegicus)
ADP [cytosol]
Prolactin receptor signaling (Rattus norvegicus)
JAK2 phosphorylation (Rattus norvegicus)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Rattus norvegicus)
ADP [cytosol]
Signaling by Interleukins (Rattus norvegicus)
Interleukin-1 family signaling (Rattus norvegicus)
Interleukin-1 signaling (Rattus norvegicus)
IKBA is phosphorylated by Phospho IKKB kinase (Rattus norvegicus)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Rattus norvegicus)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Rattus norvegicus)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Rattus norvegicus)
ADP [cytosol]
Interleukin-37 signaling (Rattus norvegicus)
STAT3 phosphorylation (Rattus norvegicus)
ADP [cytosol]
TBK1 phosphorylation (Rattus norvegicus)
ADP [cytosol]
Interleukin-38 signaling (Rattus norvegicus)
MAPK8 phosphorylation (Rattus norvegicus)
ADP [cytosol]
Interleukin-10 signaling (Rattus norvegicus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Rattus norvegicus)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Rattus norvegicus)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Rattus norvegicus)
ADP [cytosol]
Interleukin-12 family signaling (Rattus norvegicus)
Interleukin-12 signaling (Rattus norvegicus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Rattus norvegicus)
ADP [cytosol]
Interleukin-23 signaling (Rattus norvegicus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Rattus norvegicus)
ADP [cytosol]
Interleukin-27 signaling (Rattus norvegicus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Rattus norvegicus)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Rattus norvegicus)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Rattus norvegicus)
ADP [cytosol]
Interleukin-35 Signalling (Rattus norvegicus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Rattus norvegicus)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Rattus norvegicus)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Rattus norvegicus)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Rattus norvegicus)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Rattus norvegicus)
ADP [cytosol]
Interleukin-17 signaling (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
Interleukin-2 family signaling (Rattus norvegicus)
Interleukin receptor SHC signaling (Rattus norvegicus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Rattus norvegicus)
ADP [cytosol]
Interleukin-15 signaling (Rattus norvegicus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Rattus norvegicus)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Rattus norvegicus)
ADP [cytosol]
Interleukin-2 signaling (Rattus norvegicus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Rattus norvegicus)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Rattus norvegicus)
ADP [cytosol]
SYK is a substrate for JAK1 (Rattus norvegicus)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Rattus norvegicus)
ADP [cytosol]
Interleukin-21 signaling (Rattus norvegicus)
IL21 receptor JAK phosphorylation (Rattus norvegicus)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Rattus norvegicus)
ADP [cytosol]
Interleukin-9 signaling (Rattus norvegicus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Rattus norvegicus)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Rattus norvegicus)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Rattus norvegicus)
ADP [cytosol]
Interleukin-20 family signaling (Rattus norvegicus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Rattus norvegicus)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Rattus norvegicus)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Rattus norvegicus)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Rattus norvegicus)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Rattus norvegicus)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Rattus norvegicus)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Rattus norvegicus)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Rattus norvegicus)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Rattus norvegicus)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Rattus norvegicus)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Rattus norvegicus)
Activation of STAT5a/b by JAK2 (Rattus norvegicus)
ADP [cytosol]
Interleukin receptor SHC signaling (Rattus norvegicus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Rattus norvegicus)
ADP [cytosol]
JAK2 is phosphorylated, activated (Rattus norvegicus)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Rattus norvegicus)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Rattus norvegicus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Rattus norvegicus)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Rattus norvegicus)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)
ADP [cytosol]
Interleukin-6 family signaling (Rattus norvegicus)
Interleukin-6 signaling (Rattus norvegicus)
IL6ST is tyrosine phosphorylated (Rattus norvegicus)
ADP [cytosol]
JAK activation (Rattus norvegicus)
ADP [cytosol]
PTPN11 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
Serine phosphorylation of STATs (Rattus norvegicus)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Rattus norvegicus)
ADP [cytosol]
Interleukin-7 signaling (Rattus norvegicus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Rattus norvegicus)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Rattus norvegicus)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Rattus norvegicus)
NIK-->noncanonical NF-kB signaling (Rattus norvegicus)
Active NIK phosphorylates IKKA dimer (Rattus norvegicus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Rattus norvegicus)
ADP [cytosol]
NIK autophosphorylates on T559 (Rattus norvegicus)
ADP [cytosol]
Innate Immune System (Rattus norvegicus)
Alpha-protein kinase 1 signaling pathway (Rattus norvegicus)
ALPK1 phosphorylates TIFA (Rattus norvegicus)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Rattus norvegicus)
ADP [cytosol]
Antimicrobial peptides (Rattus norvegicus)
Ion influx/efflux at host-pathogen interface (Rattus norvegicus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Rattus norvegicus)
ADP [cytosol]
C-type lectin receptors (CLRs) (Rattus norvegicus)
CD209 (DC-SIGN) signaling (Rattus norvegicus)
PAK phosphorylates p21 RAF1 on S338 (Rattus norvegicus)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Rattus norvegicus)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Rattus norvegicus)
Dectin-1 mediated noncanonical NF-kB signaling (Rattus norvegicus)
Active NIK phosphorylates IKKA dimer (Rattus norvegicus)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Rattus norvegicus)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Rattus norvegicus)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Rattus norvegicus)
ADP [cytosol]
Dectin-2 family (Rattus norvegicus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Rattus norvegicus)
ADP [cytosol]
SYK autophosphorylates (Rattus norvegicus)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Rattus norvegicus)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Rattus norvegicus)
STING mediated induction of host immune responses (Rattus norvegicus)
IRF3-mediated induction of type I IFN (Rattus norvegicus)
IRF3 is phosphorylated by TBK1 (Rattus norvegicus)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Rattus norvegicus)
ADP [cytosol]
STAT6-mediated induction of chemokines (Rattus norvegicus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Rattus norvegicus)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Rattus norvegicus)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Rattus norvegicus)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Rattus norvegicus)
RIP-mediated NFkB activation via ZBP1 (Rattus norvegicus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
DAP12 interactions (Rattus norvegicus)
DAP12 signaling (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SYK (Rattus norvegicus)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Rattus norvegicus)
TRAF6 mediated NF-kB activation (Rattus norvegicus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Rattus norvegicus)
Autophosphorylation of LYN kinase (Rattus norvegicus)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Rattus norvegicus)
Autophosphorylation of BTK/ITK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Rattus norvegicus)
ADP [cytosol]
FCERI mediated MAPK activation (Rattus norvegicus)
Autophosphorylation of PAK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and activation of VAV (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MEK7 by MEKK1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
FCERI mediated NF-kB activation (Rattus norvegicus)
Activation of TAK1 complex bound to pUb-TRAF6 (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of PKC-theta (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of PKC-theta (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Rattus norvegicus)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Rattus norvegicus)
Phosphorylation of NTAL by p-SYK/Lyn (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Rattus norvegicus)
FCGR activation (Rattus norvegicus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Rattus norvegicus)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Rattus norvegicus)
ABL phosphorylates WAVEs (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of PAK1 (Rattus norvegicus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Rattus norvegicus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Rattus norvegicus)
Actin:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Detachment of WASP/WAVE (Rattus norvegicus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Rattus norvegicus)
Actin:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Rattus norvegicus)
Actin filament bound Myosin-X [plasma membrane] (Rattus norvegicus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of VAV (Rattus norvegicus)
ADP [cytosol]
Role of myosins in phagosome formation (Rattus norvegicus)
Myosin-Actin filaments [cytosol] (Rattus norvegicus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Rattus norvegicus)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Rattus norvegicus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Rattus norvegicus)
ADP [cytosol]
Role of phospholipids in phagocytosis (Rattus norvegicus)
DAG stimulates protein kinase C-delta (Rattus norvegicus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and activation of PLCG (Rattus norvegicus)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Rattus norvegicus)
NOD1/2 Signaling Pathway (Rattus norvegicus)
Activation of p38 MAPK (Rattus norvegicus)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Rattus norvegicus)
ADP [cytosol]
Toll-like Receptor Cascades (Rattus norvegicus)
Toll Like Receptor 10 (TLR10) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Rattus norvegicus)
Toll Like Receptor TLR1:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Rattus norvegicus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Rattus norvegicus)
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Rattus norvegicus)
MyD88-independent TLR4 cascade (Rattus norvegicus)
TRIF (TICAM1)-mediated TLR4 signaling (Rattus norvegicus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Rattus norvegicus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Rattus norvegicus)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Rattus norvegicus)
Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Rattus norvegicus)
MyD88 cascade initiated on plasma membrane (Rattus norvegicus)
IRAK1 recruits IKK complex (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Rattus norvegicus)
MyD88 dependent cascade initiated on endosome (Rattus norvegicus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Rattus norvegicus)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Rattus norvegicus)
ADP [cytosol]
MAP kinase activation (Rattus norvegicus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
ADP [cytosol]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Pyruvate metabolism (Rattus norvegicus)
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
ADP [cytosol]
Regulation of pyruvate metabolism (Rattus norvegicus)
NEK1 phosphorylates ME1 (Rattus norvegicus)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Rattus norvegicus)
Mitochondrial Uncoupling (Rattus norvegicus)
The proton buffering model (Rattus norvegicus)
Protons are translocated from the intermembrane space to the matrix (Rattus norvegicus)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
Transport and synthesis of PAPS (Rattus norvegicus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Rattus norvegicus)
ADP [cytosol]
Glutathione conjugation (Rattus norvegicus)
Glutathione synthesis and recycling (Rattus norvegicus)
GCL ligates L-Glu to L-Cys (Rattus norvegicus)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Rattus norvegicus)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Rattus norvegicus)
ADP [cytosol]
Inositol phosphate metabolism (Rattus norvegicus)
Synthesis of IP3 and IP4 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Rattus norvegicus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Rattus norvegicus)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Rattus norvegicus)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Rattus norvegicus)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Rattus norvegicus)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Rattus norvegicus)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)
ADP [cytosol]
Integration of energy metabolism (Rattus norvegicus)
Regulation of insulin secretion (Rattus norvegicus)
Acetylcholine regulates insulin secretion (Rattus norvegicus)
Protein kinase C, alpha type phosphorylates MARCKS (Rattus norvegicus)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Rattus norvegicus)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Creatine metabolism (Rattus norvegicus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Rattus norvegicus)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Rattus norvegicus)
ADP [cytosol]
Glutamate and glutamine metabolism (Rattus norvegicus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Rattus norvegicus)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Rattus norvegicus)
ADP [cytosol]
Histidine catabolism (Rattus norvegicus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Rattus norvegicus)
ADP [cytosol]
Metabolism of carbohydrates (Rattus norvegicus)
Formation of xylulose-5-phosphate (Rattus norvegicus)
XYLB phosphorylates D-xylulose (Rattus norvegicus)
ADP [cytosol]
Fructose metabolism (Rattus norvegicus)
Fructose catabolism (Rattus norvegicus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Rattus norvegicus)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Rattus norvegicus)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Rattus norvegicus)
ADP [cytosol]
Galactose catabolism (Rattus norvegicus)
GALK1 phosphorylates Gal to Gal1P (Rattus norvegicus)
ADP [cytosol]
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Rattus norvegicus)
ADP [cytosol]
Glycolysis (Rattus norvegicus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Rattus norvegicus)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Rattus norvegicus)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Rattus norvegicus)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Rattus norvegicus)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Rattus norvegicus)
ADP [cytosol]
Glycogen metabolism (Rattus norvegicus)
Glycogen breakdown (glycogenolysis) (Rattus norvegicus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Rattus norvegicus)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Rattus norvegicus)
ADP [cytosol]
Glycosaminoglycan metabolism (Rattus norvegicus)
Transport and synthesis of PAPS (Rattus norvegicus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Rattus norvegicus)
ADP [cytosol]
Pentose phosphate pathway (Rattus norvegicus)
RBKS phosphorylates ribose to R5P (Rattus norvegicus)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Rattus norvegicus)
ADP [cytosol]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Arachidonic acid metabolism (Rattus norvegicus)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Rattus norvegicus)
ALOX5 is phosphorylated by MAPKAP2 (Rattus norvegicus)
ADP [cytosol]
Carnitine metabolism (Rattus norvegicus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Rattus norvegicus)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
ACLY tetramer transforms CIT to Ac-CoA (Rattus norvegicus)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Rattus norvegicus)
ADP [cytosol]
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Recycling of bile acids and salts (Rattus norvegicus)
ABCB11 transports bile salts from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
ABCB11 transports bile salts from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
Cholesterol biosynthesis (Rattus norvegicus)
MVD decarboxylates MVA5PP to IPPP (Rattus norvegicus)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Rattus norvegicus)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Rattus norvegicus)
ADP [cytosol]
Phospholipid metabolism (Rattus norvegicus)
Glycerophospholipid biosynthesis (Rattus norvegicus)
Synthesis of PC (Rattus norvegicus)
Casein kinase II phosphorylates STARD10 (Rattus norvegicus)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Rattus norvegicus)
ADP [cytosol]
Synthesis of PE (Rattus norvegicus)
ETA is phosphorylated to PETA by CHK/ETNK (Rattus norvegicus)
ADP [cytosol]
PI Metabolism (Rattus norvegicus)
Synthesis of PIPs at the ER membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Rattus norvegicus)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Rattus norvegicus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Rattus norvegicus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Rattus norvegicus)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Rattus norvegicus)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Rattus norvegicus)
BMX phosphorylates RUFY1 (Rattus norvegicus)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
Sphingolipid metabolism (Rattus norvegicus)
Glycosphingolipid metabolism (Rattus norvegicus)
Glycosphingolipid biosynthesis (Rattus norvegicus)
CERK phosphorylates CERA to form C1P (Rattus norvegicus)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Rattus norvegicus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Rattus norvegicus)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Rattus norvegicus)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Rattus norvegicus)
ADP [cytosol]
Triglyceride metabolism (Rattus norvegicus)
Triglyceride biosynthesis (Rattus norvegicus)
Conversion of Glycerol to Glycerol-3-phosphate (Rattus norvegicus)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Rattus norvegicus)
eNOS activation (Rattus norvegicus)
AKT1 phosphorylates eNOS (Rattus norvegicus)
ADP [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Rattus norvegicus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Rattus norvegicus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Rattus norvegicus)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Rattus norvegicus)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Rattus norvegicus)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Rattus norvegicus)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Rattus norvegicus)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Rattus norvegicus)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Rattus norvegicus)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Rattus norvegicus)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Rattus norvegicus)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Rattus norvegicus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Rattus norvegicus)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Rattus norvegicus)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Rattus norvegicus)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Rattus norvegicus)
ADP [cytosol]
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Rattus norvegicus)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Rattus norvegicus)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Rattus norvegicus)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Rattus norvegicus)
ADP [cytosol]
Pyrimidine biosynthesis (Rattus norvegicus)
CAD hexamer transforms L-Gln to CAP (Rattus norvegicus)
ADP [cytosol]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Rattus norvegicus)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Rattus norvegicus)
ADP [cytosol]
Pyrimidine catabolism (Rattus norvegicus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Rattus norvegicus)
ADP [cytosol]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Rattus norvegicus)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Rattus norvegicus)
ADP [cytosol]
Pyrimidine salvage (Rattus norvegicus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Rattus norvegicus)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Rattus norvegicus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Rattus norvegicus)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Rattus norvegicus)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Rattus norvegicus)
ADP [cytosol]
Metabolism of porphyrins (Rattus norvegicus)
Heme biosynthesis (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
Heme degradation (Rattus norvegicus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Rattus norvegicus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Rattus norvegicus)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Rattus norvegicus)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Transport of RCbl within the body (Rattus norvegicus)
ABCC1 transports cytosolic RCbl to extracellular region (Rattus norvegicus)
ADP [cytosol]
Metabolism of folate and pterines (Rattus norvegicus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Rattus norvegicus)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Rattus norvegicus)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Rattus norvegicus)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Rattus norvegicus)
ADP [cytosol]
Nicotinate metabolism (Rattus norvegicus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Rattus norvegicus)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Rattus norvegicus)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Rattus norvegicus)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Rattus norvegicus)
RFK:Mg2+ phosphorylates RIB (Rattus norvegicus)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Rattus norvegicus)
Coenzyme A biosynthesis (Rattus norvegicus)
COASY phosphorylates DP-CoA (Rattus norvegicus)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Rattus norvegicus)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Rattus norvegicus)
ADP [cytosol]
PANK2 phosphorylates PanK (Rattus norvegicus)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Rattus norvegicus)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Rattus norvegicus)
2xPDKX:2xZn2+ phosphorylates PDX (Rattus norvegicus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Rattus norvegicus)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Rattus norvegicus)
ADP [cytosol]
Metabolism of RNA (Rattus norvegicus)
Nonsense-Mediated Decay (NMD) (Rattus norvegicus)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Rattus norvegicus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Rattus norvegicus)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Rattus norvegicus)
MK2 phosphorylates BRF1 (Rattus norvegicus)
ADP [cytosol]
Protein Kinase B/Akt phosphorylates BRF1 (Rattus norvegicus)
ADP [cytosol]
KSRP (KHSRP) binds and destabilizes mRNA (Rattus norvegicus)
Protein Kinase B (AKT) phosphorylates KSRP (Rattus norvegicus)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Rattus norvegicus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Rattus norvegicus)
ADP [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
Synthesis of substrates in N-glycan biosythesis (Rattus norvegicus)
GDP-fucose biosynthesis (Rattus norvegicus)
FUK phosphorylates beta-Fuc to Fuc1P (Rattus norvegicus)
ADP [cytosol]
Sialic acid metabolism (Rattus norvegicus)
GNE phosphorylates ManNAc to ManNAc-6-P (Rattus norvegicus)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Rattus norvegicus)
MVD decarboxylates MVA5PP to IPPP (Rattus norvegicus)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Rattus norvegicus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Rattus norvegicus)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Rattus norvegicus)
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPI-mediated anterograde transport (Rattus norvegicus)
GBF1 stimulates ARF nucleotide exchange (Rattus norvegicus)
ADP [cytosol]
COPII-mediated vesicle transport (Rattus norvegicus)
CSNK1D phosphorylates SEC23 (Rattus norvegicus)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Rattus norvegicus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Rattus norvegicus)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Rattus norvegicus)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
FN3K phosphorylates ketosamines (Rattus norvegicus)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Rattus norvegicus)
ADP [cytosol]
Protein folding (Rattus norvegicus)
Chaperonin-mediated protein folding (Rattus norvegicus)
Association of TriC/CCT with target proteins during biosynthesis (Rattus norvegicus)
Association of CCT/TriC with sphingosine kinase 1 (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Rattus norvegicus)
ATP binds G-protein beta associated TRiC/CCT (Rattus norvegicus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Rattus norvegicus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
CK2 phosphorylates PDCL (Rattus norvegicus)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Rattus norvegicus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Rattus norvegicus)
GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Rattus norvegicus)
GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Rattus norvegicus)
GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Rattus norvegicus)
GNB5:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Surfactant metabolism (Rattus norvegicus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Rattus norvegicus)
ADP [cytosol]
Translation (Rattus norvegicus)
Eukaryotic Translation Initiation (Rattus norvegicus)
Cap-dependent Translation Initiation (Rattus norvegicus)
Ribosomal scanning and start codon recognition (Rattus norvegicus)
Ribosomal scanning (Rattus norvegicus)
ADP [cytosol]
Muscle contraction (Rattus norvegicus)
Cardiac conduction (Rattus norvegicus)
Ion homeostasis (Rattus norvegicus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Rattus norvegicus)
ADP [cytosol]
DMPK phosphorylates PLN (Rattus norvegicus)
ADP [cytosol]
PRKACA phosphorylates PLN (Rattus norvegicus)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Rattus norvegicus)
ADP [cytosol]
Smooth Muscle Contraction (Rattus norvegicus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Rattus norvegicus)
ADP [cytosol]
Release Of ADP From Myosin (Rattus norvegicus)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Rattus norvegicus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Rattus norvegicus)
ADP [cytosol]
Striated Muscle Contraction (Rattus norvegicus)
ATP Hydrolysis By Myosin (Rattus norvegicus)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Rattus norvegicus)
ADP Bound Myosin Complex [cytosol] (Rattus norvegicus)
ADP [cytosol]
Release Of ADP From Myosin (Rattus norvegicus)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Rattus norvegicus)
ADP Bound Myosin Complex [cytosol] (Rattus norvegicus)
ADP [cytosol]
Neuronal System (Rattus norvegicus)
Transmission across Chemical Synapses (Rattus norvegicus)
Neurotransmitter receptors and postsynaptic signal transmission (Rattus norvegicus)
Activation of NMDA receptors and postsynaptic events (Rattus norvegicus)
Post NMDA receptor activation events (Rattus norvegicus)
Activation of RAC1 downstream of NMDARs (Rattus norvegicus)
CaMKK autophosphorylates in the cytosol (Rattus norvegicus)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Rattus norvegicus)
Trafficking of AMPA receptors (Rattus norvegicus)
Trafficking of GluR1-containing AMPA receptors (Rattus norvegicus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Rattus norvegicus)
Endocytosis of Ca impermeable AMPA receptors (Rattus norvegicus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Rattus norvegicus)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Rattus norvegicus)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Rattus norvegicus)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Rattus norvegicus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Rattus norvegicus)
ADP [cytosol]
Programmed Cell Death (Rattus norvegicus)
Apoptosis (Rattus norvegicus)
Caspase activation via extrinsic apoptotic signalling pathway (Rattus norvegicus)
Caspase activation via Dependence Receptors in the absence of ligand (Rattus norvegicus)
Activation of caspase-3 (Rattus norvegicus)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Rattus norvegicus)
Activation of BH3-only proteins (Rattus norvegicus)
Activation of BIM and translocation to mitochondria (Rattus norvegicus)
Phosphorylation of BIM by JNK (Rattus norvegicus)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Rattus norvegicus)
Phosphorylation of DLC2 by MAPK8 (Rattus norvegicus)
ADP [cytosol]
Apoptotic factor-mediated response (Rattus norvegicus)
Cytochrome c-mediated apoptotic response (Rattus norvegicus)
Activation of caspases through apoptosome-mediated cleavage (Rattus norvegicus)
Cleavage of Procaspase-3 by the apoptosome (Rattus norvegicus)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)
ADP [cytosol]
Formation of apoptosome (Rattus norvegicus)
CYCS binds to APAF1 (Rattus norvegicus)
ADP [cytosol]
APAF1:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)
ADP [cytosol]
Regulation of the apoptosome activity (Rattus norvegicus)
APAF1 binds AVEN (Rattus norvegicus)
APAF1:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
APAF1:AVEN [cytosol] (Rattus norvegicus)
APAF1:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Rattus norvegicus)
ADP [cytosol]
Regulated Necrosis (Rattus norvegicus)
RIPK1-mediated regulated necrosis (Rattus norvegicus)
RIPK1 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
RIPK3 is phosphorylated (Rattus norvegicus)
ADP [cytosol]
RIPK3 phosphorylates MLKL (Rattus norvegicus)
ADP [cytosol]
Protein localization (Rattus norvegicus)
Peroxisomal protein import (Rattus norvegicus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Rattus norvegicus)
ADP [cytosol]
Sensory Perception (Rattus norvegicus)
Visual phototransduction (Rattus norvegicus)
The phototransduction cascade (Rattus norvegicus)
Inactivation, recovery and regulation of the phototransduction cascade (Rattus norvegicus)
GRK1,4,7 phosphorylate MII to p-MII (Rattus norvegicus)
ADP [cytosol]
Signal Transduction (Rattus norvegicus)
Death Receptor Signaling (Rattus norvegicus)
TNF signaling (Rattus norvegicus)
Regulation of TNFR1 signaling (Rattus norvegicus)
CHUK, IKBKB phosphorylate CYLD at S418 (Rattus norvegicus)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Rattus norvegicus)
ADP [cytosol]
MAPKAPK2 phosphorylates RIPK1 at S320 (Rattus norvegicus)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Rattus norvegicus)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Rattus norvegicus)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Rattus norvegicus)
Cell death signalling via NRAGE, NRIF and NADE (Rattus norvegicus)
NRAGE signals death through JNK (Rattus norvegicus)
GTP-bound RAC contributes to JNK activation (Rattus norvegicus)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Rattus norvegicus)
ADP [cytosol]
p75NTR signals via NF-kB (Rattus norvegicus)
NF-kB is activated and signals survival (Rattus norvegicus)
IKKbeta is activated (Rattus norvegicus)
ADP [cytosol]
Integrin signaling (Rattus norvegicus)
Autophosphorylation of PTK2 at Y397 (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of SRC (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Rattus norvegicus)
ADP [cytosol]
SYK activation by SRC (Rattus norvegicus)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Rattus norvegicus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)
ADP [cytosol]
Intracellular signaling by second messengers (Rattus norvegicus)
DAG and IP3 signaling (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
PKC phosphorylates GRK2 (Rattus norvegicus)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Rattus norvegicus)
ADP [cytosol]
PIP3 activates AKT signaling (Rattus norvegicus)
AKT phosphorylates targets in the cytosol (Rattus norvegicus)
AKT phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates IKKalpha (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates MDM2 (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates MKRN1 (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates caspase-9 (Rattus norvegicus)
ADP [cytosol]
AKT phosphorylates p21Cip1 and p27Kip1 (Rattus norvegicus)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Rattus norvegicus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Rattus norvegicus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Rattus norvegicus)
ADP [cytosol]
MAPKs phosphorylate PP2A (Rattus norvegicus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Rattus norvegicus)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Rattus norvegicus)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
PTEN Regulation (Rattus norvegicus)
Regulation of PTEN gene transcription (Rattus norvegicus)
mTORC1 phosphorylates MAF1 (Rattus norvegicus)
ADP [cytosol]
Regulation of PTEN stability and activity (Rattus norvegicus)
AKT phosphorylates MKRN1 (Rattus norvegicus)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Rattus norvegicus)
ADP [cytosol]
FRK phosphorylates PTEN (Rattus norvegicus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Rattus norvegicus)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Rattus norvegicus)
ADP [cytosol]
MAPK family signaling cascades (Rattus norvegicus)
MAPK1/MAPK3 signaling (Rattus norvegicus)
RAF-independent MAPK1/3 activation (Rattus norvegicus)
MAPK1 (ERK2) activation (Rattus norvegicus)
MAP2K2 phosphorylates MAPK1 (Rattus norvegicus)
ADP [cytosol]
MAPK3 (ERK1) activation (Rattus norvegicus)
Inactivation of MAP2K1 by CDK1 (Rattus norvegicus)
ADP [cytosol]
MAP2K1 phosphorylates MAPK3 (Rattus norvegicus)
ADP [cytosol]
RAF/MAP kinase cascade (Rattus norvegicus)
MAP2K and MAPK activation (Rattus norvegicus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Rattus norvegicus)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Rattus norvegicus)
ADP [cytosol]
Negative regulation of MAPK pathway (Rattus norvegicus)
MAPK12 phosphorylates PTPN3 (Rattus norvegicus)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Rattus norvegicus)
Activated MAPK phosphorylates RAF1 (Rattus norvegicus)
ADP [cytosol]
Activated MAPKs phosphorylate BRAF (Rattus norvegicus)
ADP [cytosol]
Activated MAPKs phosphorylate MAP2K1 (Rattus norvegicus)
ADP [cytosol]
RAF activation (Rattus norvegicus)
MARK3 phosphorylates KSR1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of RAF (Rattus norvegicus)
ADP [cytosol]
RAS processing (Rattus norvegicus)
KRAS4B is phosphorylated on serine 181 (Rattus norvegicus)
ADP [cytosol]
MAPK6/MAPK4 signaling (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
ADP [cytosol]
MAPKAPK5 phosphorylates KALRN (Rattus norvegicus)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Rattus norvegicus)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Rattus norvegicus)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Rattus norvegicus)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Rattus norvegicus)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Rattus norvegicus)
ADP [cytosol]
MTOR signalling (Rattus norvegicus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
ADP [cytosol]
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Rattus norvegicus)
Phosphorylation of TSC2 by PKB (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Rattus norvegicus)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Rattus norvegicus)
ADP [cytosol]
mTORC1-mediated signalling (Rattus norvegicus)
Phosphorylation and activation of eIF4G by activated S6K1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Rattus norvegicus)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)
ADP [cytosol]
Signaling by Erythropoietin (Rattus norvegicus)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Rattus norvegicus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Rattus norvegicus)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Rattus norvegicus)
ADP [cytosol]
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Rattus norvegicus)
ADP [cytosol]
Opioid Signalling (Rattus norvegicus)
DARPP-32 events (Rattus norvegicus)
PKA phosphorylates DARPP-32 on Thr34 (Rattus norvegicus)
ADP [cytosol]
PKA phosphorylates PDE4B (Rattus norvegicus)
ADP [cytosol]
G-protein mediated events (Rattus norvegicus)
PLC beta mediated events (Rattus norvegicus)
Ca-dependent events (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
PKC phosphorylates GRK2 (Rattus norvegicus)
ADP [cytosol]
phospho-PLA2 pathway (Rattus norvegicus)
Phosphorylation of cPLA2 by ERK-2 (Rattus norvegicus)
ADP [cytosol]
G alpha (q) signalling events (Rattus norvegicus)
Effects of PIP2 hydrolysis (Rattus norvegicus)
DAG kinase produces phosphatidic acid from DAG (Rattus norvegicus)
ADP [cytosol]
G alpha (s) signalling events (Rattus norvegicus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Rattus norvegicus)
ADP [cytosol]
G-protein beta:gamma signalling (Rattus norvegicus)
G beta:gamma signalling through PI3Kgamma (Rattus norvegicus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Signaling by Hedgehog (Rattus norvegicus)
Hedgehog 'off' state (Rattus norvegicus)
GLI3 is processed to GLI3R by the proteasome (Rattus norvegicus)
CK1 phosphorylates p-GLI3 (Rattus norvegicus)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Rattus norvegicus)
ADP [cytosol]
PKA phosphorylates GLI3 (Rattus norvegicus)
ADP [cytosol]
Hedgehog ligand biogenesis (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
ADP [cytosol]
Signaling by Hippo (Rattus norvegicus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Rattus norvegicus)
ADP [cytosol]
Signaling by NOTCH (Rattus norvegicus)
Signaling by NOTCH3 (Rattus norvegicus)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Rattus norvegicus)
EGFR phosphorylates NOTCH3 (Rattus norvegicus)
ADP [cytosol]
Signaling by NOTCH4 (Rattus norvegicus)
Negative regulation of NOTCH4 signaling (Rattus norvegicus)
AKT1 phosphorylates NOTCH4 (Rattus norvegicus)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by PTK6 (Rattus norvegicus)
ERBB2 Activates PTK6 Signaling (Rattus norvegicus)
ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)
ADP [cytosol]
PTK6 Activates STAT3 (Rattus norvegicus)
PTK6 phosphorylates STAP2 (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
PTK6 Down-Regulation (Rattus norvegicus)
SRMS phosphorylates PTK6 (Rattus norvegicus)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Rattus norvegicus)
PTK6 phosphorylates CDKN1B (Rattus norvegicus)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Rattus norvegicus)
PTK6 phosphorylates ARHGAP35 (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates PXN (Rattus norvegicus)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Rattus norvegicus)
PTK6 phosphorylates AKT1 (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates ARAP1 (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates CBL (Rattus norvegicus)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Rattus norvegicus)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Rattus norvegicus)
EGFR phosphorylates GPNMB (Rattus norvegicus)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Rattus norvegicus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Rattus norvegicus)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Rattus norvegicus)
ADP [cytosol]
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
ESR-associated SRC autophosphorylates (Rattus norvegicus)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Rattus norvegicus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Rattus norvegicus)
ADP [cytosol]
PTK2 autophosphorylates downstream of EGFR (Rattus norvegicus)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by ALK (Rattus norvegicus)
ALK autophosphorylation (Rattus norvegicus)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Rattus norvegicus)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Rattus norvegicus)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
ADP [cytosol]
Signaling by EGFR (Rattus norvegicus)
EGFR autophosphorylation (Rattus norvegicus)
ADP [cytosol]
EGFR downregulation (Rattus norvegicus)
EGFR phosphorylates EPS15 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Rattus norvegicus)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Rattus norvegicus)
EGFR activates PLC-gamma1 by phosphorylation (Rattus norvegicus)
ADP [cytosol]
GAB1 signalosome (Rattus norvegicus)
GAB1 phosphorylation by EGFR kinase (Rattus norvegicus)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Rattus norvegicus)
ADP [cytosol]
SHC1 events in EGFR signaling (Rattus norvegicus)
SHC1 phosphorylation by phosphorylated EGFR (Rattus norvegicus)
ADP [cytosol]
Signaling by ERBB2 (Rattus norvegicus)
Downregulation of ERBB2 signaling (Rattus norvegicus)
Downregulation of ERBB2:ERBB3 signaling (Rattus norvegicus)
Phosphorylation of USP8 by P-AKT (Rattus norvegicus)
ADP [cytosol]
ERBB2 Activates PTK6 Signaling (Rattus norvegicus)
ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)
ADP [cytosol]
PI3K events in ERBB2 signaling (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Rattus norvegicus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Rattus norvegicus)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Rattus norvegicus)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Rattus norvegicus)
Activated PKC phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Rattus norvegicus)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Rattus norvegicus)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Rattus norvegicus)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Rattus norvegicus)
ADP [cytosol]
Signaling by ERBB4 (Rattus norvegicus)
PI3K events in ERBB4 signaling (Rattus norvegicus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Rattus norvegicus)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Rattus norvegicus)
Phosphorylation of SHC1 by ERBB4 homodimers (Rattus norvegicus)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Rattus norvegicus)
ADP [cytosol]
Signaling by FGFR (Rattus norvegicus)
Signaling by FGFR1 (Rattus norvegicus)
Downstream signaling of activated FGFR1 (Rattus norvegicus)
FRS-mediated FGFR1 signaling (Rattus norvegicus)
Activated FGFR1 phosphorylates FRS2 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Rattus norvegicus)
ADP [cytosol]
PI-3K cascade:FGFR1 (Rattus norvegicus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Rattus norvegicus)
Activated FGFR1 phosphorylates PLCG1 (Rattus norvegicus)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Rattus norvegicus)
Activated FGFR1 phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
FGFR1 ligand binding and activation (Rattus norvegicus)
FGFR1b ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR1b (Rattus norvegicus)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Rattus norvegicus)
ADP [cytosol]
FGFR1c ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR1c (Rattus norvegicus)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Rattus norvegicus)
ADP [cytosol]
Spry regulation of FGF signaling (Rattus norvegicus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)
ADP [cytosol]
Signaling by FGFR2 (Rattus norvegicus)
Downstream signaling of activated FGFR2 (Rattus norvegicus)
FRS-mediated FGFR2 signaling (Rattus norvegicus)
Activated FGFR2 phosphorylates FRS2 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR2 phosphorylates FRS3 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR2 phosphorylates PPTN11 (Rattus norvegicus)
ADP [cytosol]
PI-3K cascade:FGFR2 (Rattus norvegicus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR2 (Rattus norvegicus)
Activated FGFR2 phosphorylates PLCG1 (Rattus norvegicus)
ADP [cytosol]
SHC-mediated cascade:FGFR2 (Rattus norvegicus)
Activated FGFR2 phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
FGFR2 ligand binding and activation (Rattus norvegicus)
FGFR2b ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR2b (Rattus norvegicus)
ADP [cytosol]
FGFR2c ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR2c (Rattus norvegicus)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Rattus norvegicus)
ADP [cytosol]
Spry regulation of FGF signaling (Rattus norvegicus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)
ADP [cytosol]
Signaling by FGFR3 (Rattus norvegicus)
Downstream signaling of activated FGFR3 (Rattus norvegicus)
FRS-mediated FGFR3 signaling (Rattus norvegicus)
Activated FGFR3 phosphorylates FRS2 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR3 phosphorylates FRS3 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR3 phosphorylates PPTN11 (Rattus norvegicus)
ADP [cytosol]
PI-3K cascade:FGFR3 (Rattus norvegicus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR3 (Rattus norvegicus)
Activated FGFR3 phosphorylates PLCG1 (Rattus norvegicus)
ADP [cytosol]
SHC-mediated cascade:FGFR3 (Rattus norvegicus)
Activated FGFR3 phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
FGFR3 ligand binding and activation (Rattus norvegicus)
FGFR3b ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR3b (Rattus norvegicus)
ADP [cytosol]
FGFR3c ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR3c (Rattus norvegicus)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Rattus norvegicus)
ADP [cytosol]
Spry regulation of FGF signaling (Rattus norvegicus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)
ADP [cytosol]
Signaling by FGFR4 (Rattus norvegicus)
Downstream signaling of activated FGFR4 (Rattus norvegicus)
FRS-mediated FGFR4 signaling (Rattus norvegicus)
Activated FGFR4 phosphorylates FRS2 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Rattus norvegicus)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Rattus norvegicus)
ADP [cytosol]
PI-3K cascade:FGFR4 (Rattus norvegicus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Rattus norvegicus)
Activated FGFR4 phosphorylates PLCG1 (Rattus norvegicus)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Rattus norvegicus)
Activated FGFR4 phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
FGFR4 ligand binding and activation (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR4 (Rattus norvegicus)
ADP [cytosol]
betaKlotho-mediated ligand binding (Rattus norvegicus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Rattus norvegicus)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Rattus norvegicus)
ADP [cytosol]
Spry regulation of FGF signaling (Rattus norvegicus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)
ADP [cytosol]
Signaling by Insulin receptor (Rattus norvegicus)
Autophosphorylation of insulin receptor (Rattus norvegicus)
ADP [cytosol]
Insulin receptor signalling cascade (Rattus norvegicus)
IRS activation (Rattus norvegicus)
Phosphorylation of IRS (Rattus norvegicus)
ADP [cytosol]
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
Activation of AKT2 (Rattus norvegicus)
PDPK1 phosphorylates AKT2 (Rattus norvegicus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SHC1 (Rattus norvegicus)
ADP [cytosol]
Signal attenuation (Rattus norvegicus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Rattus norvegicus)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Rattus norvegicus)
ADP [cytosol]
Signaling by LTK (Rattus norvegicus)
Active LTK phosphorylates IRS1 (Rattus norvegicus)
ADP [cytosol]
Active LTK receptor phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of LTK dimer:ALKAL1,2 (Rattus norvegicus)
ADP [cytosol]
Signaling by MET (Rattus norvegicus)
MET Receptor Activation (Rattus norvegicus)
MET dimers autophosphorylate (Rattus norvegicus)
ADP [cytosol]
MET activates PI3K/AKT signaling (Rattus norvegicus)
MET bound PI3K generates PIP3 (Rattus norvegicus)
ADP [cytosol]
MET phosphorylates GAB1 (Rattus norvegicus)
ADP [cytosol]
MET activates RAS signaling (Rattus norvegicus)
MET phosphorylates SHC1-2 (Rattus norvegicus)
ADP [cytosol]
MET activates STAT3 (Rattus norvegicus)
MET phosphorylates STAT3 (Rattus norvegicus)
ADP [cytosol]
MET promotes cell motility (Rattus norvegicus)
MET activates PTK2 signaling (Rattus norvegicus)
MET phosphorylates PTK2 (Rattus norvegicus)
ADP [cytosol]
PTK2 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
SRC phosphorylates PTK2 (Rattus norvegicus)
ADP [cytosol]
Negative regulation of MET activity (Rattus norvegicus)
MET phosphorylates CBL (Rattus norvegicus)
ADP [cytosol]
Signaling by MST1 (Rattus norvegicus)
MST1R autophosphorylates (Rattus norvegicus)
ADP [cytosol]
Signaling by NTRKs (Rattus norvegicus)
Signaling by NTRK1 (TRKA) (Rattus norvegicus)
PI3K/AKT activation (Rattus norvegicus)
PI3K produces PIP3 and other phosphatidyl inositides (Rattus norvegicus)
ADP [cytosol]
Signalling to ERKs (Rattus norvegicus)
Prolonged ERK activation events (Rattus norvegicus)
ARMS-mediated activation (Rattus norvegicus)
ARMS is phosphorylated by active TrkA receptor (Rattus norvegicus)
ADP [cytosol]
Frs2-mediated activation (Rattus norvegicus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Rattus norvegicus)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Rattus norvegicus)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Rattus norvegicus)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Rattus norvegicus)
ADP [cytosol]
Signalling to RAS (Rattus norvegicus)
p38MAPK events (Rattus norvegicus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Rattus norvegicus)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Rattus norvegicus)
Activated NTRK3 signals through PI3K (Rattus norvegicus)
Activated NTRK3 promotes SRC autophosphorylation (Rattus norvegicus)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Rattus norvegicus)
NTRK3 dimers trans-autophosphorylate (Rattus norvegicus)
ADP [cytosol]
Signaling by PDGF (Rattus norvegicus)
Autophosphorylation of PDGF alpha receptors (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Rattus norvegicus)
ADP [cytosol]
Downstream signal transduction (Rattus norvegicus)
Activation of Src (Rattus norvegicus)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Rattus norvegicus)
ADP [cytosol]
Signaling by SCF-KIT (Rattus norvegicus)
Autophosphorylation of KIT (Rattus norvegicus)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of JAK2 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of STATs (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Rattus norvegicus)
ADP [cytosol]
Regulation of KIT signaling (Rattus norvegicus)
PKC alpha interacts with and phosphorylates KIT (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of APS (Rattus norvegicus)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Rattus norvegicus)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Rattus norvegicus)
IGF1,2:IGF1R autophosphorylates (Rattus norvegicus)
ADP [cytosol]
IGF1R signaling cascade (Rattus norvegicus)
IRS-related events triggered by IGF1R (Rattus norvegicus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Rattus norvegicus)
ADP [cytosol]
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
Activation of AKT2 (Rattus norvegicus)
PDPK1 phosphorylates AKT2 (Rattus norvegicus)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
SHC-related events triggered by IGF1R (Rattus norvegicus)
IGF1R phosphorylates SHC1 (Rattus norvegicus)
ADP [cytosol]
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
AXL autophosphorylates on Y779 and Y821 (Rattus norvegicus)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Rattus norvegicus)
ADP [cytosol]
FYN autophosphorylates (Rattus norvegicus)
ADP [cytosol]
FYN phosphorylates PAK2 (Rattus norvegicus)
ADP [cytosol]
PAK2 autophorylates (Rattus norvegicus)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Rattus norvegicus)
ADP [cytosol]
PTK2 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SRC-1 (Rattus norvegicus)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Rattus norvegicus)
ADP [cytosol]
SRC-1 phosphorylates SHB (Rattus norvegicus)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Rattus norvegicus)
ADP [cytosol]
Src kinases phosphorylate VAV (Rattus norvegicus)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
ADP [cytosol]
VEGFR2 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Rattus norvegicus)
PDK1 phosphorylates PKC (Rattus norvegicus)
ADP [cytosol]
PKC autophosphorylates (Rattus norvegicus)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Rattus norvegicus)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Rattus norvegicus)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Rattus norvegicus)
AKT1 phosphorylates eNOS (Rattus norvegicus)
ADP [cytosol]
PAK1-3 autophosphorylates (Rattus norvegicus)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Rattus norvegicus)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Rattus norvegicus)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Rattus norvegicus)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Rattus norvegicus)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Rattus norvegicus)
ADP [cytosol]
p38 MAPK activation by VEGFR (Rattus norvegicus)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Rattus norvegicus)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
RHOBTB3 ATPase cycle (Rattus norvegicus)
RHOBTB3 hydrolyzes ATP (Rattus norvegicus)
RHOBTB3:ADP [trans-Golgi network membrane] (Rattus norvegicus)
ADP [cytosol]
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases Activate Formins (Rattus norvegicus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Rattus norvegicus)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Rattus norvegicus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Rattus norvegicus)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Rattus norvegicus)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Rattus norvegicus)
ADP [cytosol]
PKC phosphorylates NCF1 (Rattus norvegicus)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Rattus norvegicus)
ABL phosphorylates WAVEs (Rattus norvegicus)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Rattus norvegicus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Rattus norvegicus)
Actin:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Detachment of WASP/WAVE (Rattus norvegicus)
Mother filament:ARP2/3:actin:ADP [cytosol] (Rattus norvegicus)
Actin:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
Src phosphorylate WASP,N-WASP (Rattus norvegicus)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Rattus norvegicus)
ADP [cytosol]
RHO GTPases activate PAKs (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Rattus norvegicus)
ADP [cytosol]
PAK1 phosphorylates FLNA (Rattus norvegicus)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Rattus norvegicus)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Rattus norvegicus)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Rattus norvegicus)
ADP [cytosol]
RHO GTPases activate PKNs (Rattus norvegicus)
PDPK1 phosphorylates PKN1,2,3 (Rattus norvegicus)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Rattus norvegicus)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Rattus norvegicus)
ADP [cytosol]
Signaling by TGFB family members (Rattus norvegicus)
Signaling by Activin (Rattus norvegicus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Rattus norvegicus)
ADP [cytosol]
Signaling by BMP (Rattus norvegicus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Rattus norvegicus)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Rattus norvegicus)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Rattus norvegicus)
TGF-beta receptor signaling activates SMADs (Rattus norvegicus)
Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Rattus norvegicus)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Rattus norvegicus)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Rattus norvegicus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Rattus norvegicus)
ADP [cytosol]
Signaling by WNT (Rattus norvegicus)
Beta-catenin independent WNT signaling (Rattus norvegicus)
Ca2+ pathway (Rattus norvegicus)
Activation of NLK (Rattus norvegicus)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Rattus norvegicus)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Rattus norvegicus)
ADP [cytosol]
PCP/CE pathway (Rattus norvegicus)
WNT5A-dependent internalization of FZD4 (Rattus norvegicus)
DVL2 is phosphorylated by PKC (Rattus norvegicus)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Rattus norvegicus)
AXIN is phosphorylated in the destruction complex (Rattus norvegicus)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Rattus norvegicus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Rattus norvegicus)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Rattus norvegicus)
ADP [cytosol]
TCF dependent signaling in response to WNT (Rattus norvegicus)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Rattus norvegicus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Rattus norvegicus)
ADP [cytosol]
WNT mediated activation of DVL (Rattus norvegicus)
CSNK2-mediated phosphorylation of DVL (Rattus norvegicus)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Rattus norvegicus)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)
ADP [cytosol]
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
ABC transporters in lipid homeostasis (Rattus norvegicus)
ABCA12 transports lipids from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Rattus norvegicus)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Rattus norvegicus)
ADP [cytosol]
ABCA7:Apo1A-mediated phospholipid efflux (Rattus norvegicus)
ADP [cytosol]
ABCAs mediate lipid efflux (Rattus norvegicus)
ADP [cytosol]
ABCAs mediate lipid influx (Rattus norvegicus)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Rattus norvegicus)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Rattus norvegicus)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Rattus norvegicus)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Rattus norvegicus)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
HCO3- transport through ion channel (Rattus norvegicus)
ADP [cytosol]
Mitochondrial ABC transporters (Rattus norvegicus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Rattus norvegicus)
ADP [cytosol]
The ABCC family mediates organic anion transport (Rattus norvegicus)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
ADP [cytosol]
Aquaporin-mediated transport (Rattus norvegicus)
Vasopressin regulates renal water homeostasis via Aquaporins (Rattus norvegicus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Rattus norvegicus)
ADP [cytosol]
Ion channel transport (Rattus norvegicus)
Ion transport by P-type ATPases (Rattus norvegicus)
ATP12A:ATP4B exchanges K+ for H+ (Rattus norvegicus)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Rattus norvegicus)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Rattus norvegicus)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Rattus norvegicus)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Rattus norvegicus)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Rattus norvegicus)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Rattus norvegicus)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Rattus norvegicus)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Rattus norvegicus)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Rattus norvegicus)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Rattus norvegicus)
ADP [cytosol]
Stimuli-sensing channels (Rattus norvegicus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Rattus norvegicus)
ADP [cytosol]
Iron uptake and transport (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
ADP [cytosol]
Transferrin endocytosis and recycling (Rattus norvegicus)
Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Rattus norvegicus)
Plasma lipoprotein assembly (Rattus norvegicus)
HDL assembly (Rattus norvegicus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Rattus norvegicus)
ADP [cytosol]
Plasma lipoprotein remodeling (Rattus norvegicus)
HDL remodeling (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
ADP [cytosol]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
ADP [cytosol]
Vesicle-mediated transport (Rattus norvegicus)
Membrane Trafficking (Rattus norvegicus)
Clathrin-mediated endocytosis (Rattus norvegicus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Rattus norvegicus)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Rattus norvegicus)
ADBRK1,2 phosphorylate AVPR2 (Rattus norvegicus)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Rattus norvegicus)
clathrin:HSPA8:ADP [cytosol] (Rattus norvegicus)
HSPA8:ADP [cytosol] (Rattus norvegicus)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Rattus norvegicus)
ADP [cytosol]
ER to Golgi Anterograde Transport (Rattus norvegicus)
COPI-mediated anterograde transport (Rattus norvegicus)
GBF1 stimulates ARF nucleotide exchange (Rattus norvegicus)
ADP [cytosol]
COPII-mediated vesicle transport (Rattus norvegicus)
CSNK1D phosphorylates SEC23 (Rattus norvegicus)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Rattus norvegicus)
ESCRT Disassembly (Rattus norvegicus)
ADP [cytosol]
Gap junction trafficking and regulation (Rattus norvegicus)
Regulation of gap junction activity (Rattus norvegicus)
Phosphorylation of Cx43 by c-src (Rattus norvegicus)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Rattus norvegicus)
Golgi-to-ER retrograde transport (Rattus norvegicus)
COPI-independent Golgi-to-ER retrograde traffic (Rattus norvegicus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Rattus norvegicus)
ADP [cytosol]
Intra-Golgi traffic (Rattus norvegicus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Rattus norvegicus)
ADP [cytosol]
Retrograde transport at the Trans-Golgi-Network (Rattus norvegicus)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Rattus norvegicus)
ADP [cytosol]
Rab regulation of trafficking (Rattus norvegicus)
RAB GEFs exchange GTP for GDP on RABs (Rattus norvegicus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Rattus norvegicus)
ADP [cytosol]
p-ULK1 phosphorylates DENND3 (Rattus norvegicus)
ADP [cytosol]
trans-Golgi Network Vesicle Budding (Rattus norvegicus)
Golgi Associated Vesicle Biogenesis (Rattus norvegicus)
trans-Golgi Network Derived Vesicle Uncoating (Rattus norvegicus)
ADP [cytosol]
Lysosome Vesicle Biogenesis (Rattus norvegicus)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Rattus norvegicus)
ADP [cytosol]
Autophagy (Saccharomyces cerevisiae)
Macroautophagy (Saccharomyces cerevisiae)
AMPK (complex) phosphorylates ULK1 (complex) (Saccharomyces cerevisiae)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Saccharomyces cerevisiae)
ADP [cytosol]
Selective autophagy (Saccharomyces cerevisiae)
Mitophagy (Saccharomyces cerevisiae)
Receptor Mediated Mitophagy (Saccharomyces cerevisiae)
FUNDC1 is phosphorylated by CK2 (Saccharomyces cerevisiae)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Saccharomyces cerevisiae)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Saccharomyces cerevisiae)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Saccharomyces cerevisiae)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)
ADP [cytosol]
Cell Cycle (Saccharomyces cerevisiae)
Cell Cycle, Mitotic (Saccharomyces cerevisiae)
M Phase (Saccharomyces cerevisiae)
Mitotic Prometaphase (Saccharomyces cerevisiae)
Condensation of Prometaphase Chromosomes (Saccharomyces cerevisiae)
CK2 phosphorylates condensin I subunits (Saccharomyces cerevisiae)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Saccharomyces cerevisiae)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Saccharomyces cerevisiae)
ADP [cytosol]
Mitotic Prophase (Saccharomyces cerevisiae)
Golgi Cisternae Pericentriolar Stack Reorganization (Saccharomyces cerevisiae)
PLK1 phosphorylates GORASP1 (Saccharomyces cerevisiae)
ADP [cytosol]
Mitotic G2-G2/M phases (Saccharomyces cerevisiae)
G2/M Transition (Saccharomyces cerevisiae)
Polo-like kinase mediated events (Saccharomyces cerevisiae)
Activation of Cdc25C (Saccharomyces cerevisiae)
ADP [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Cellular response to chemical stress (Saccharomyces cerevisiae)
KEAP1-NFE2L2 pathway (Saccharomyces cerevisiae)
Nuclear events mediated by NFE2L2 (Saccharomyces cerevisiae)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Saccharomyces cerevisiae)
SRXN1 reduces hyperoxidized PRDX1 dimer (Saccharomyces cerevisiae)
ADP [cytosol]
Cellular response to heat stress (Saccharomyces cerevisiae)
Regulation of HSF1-mediated heat shock response (Saccharomyces cerevisiae)
Constitutive phosphorylation by pERK1/2 (Saccharomyces cerevisiae)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Saccharomyces cerevisiae)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Saccharomyces cerevisiae)
ADP [cytosol]
HSP70s:ADP [cytosol] (Saccharomyces cerevisiae)
HSP13:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP14:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA2:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA4:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA5:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA6:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA8:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA9:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Saccharomyces cerevisiae)
HSP70s:ADP [cytosol] (Saccharomyces cerevisiae)
HSP13:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP14:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA2:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA4:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA5:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA6:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA8:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSPA9:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Saccharomyces cerevisiae)
ATP binding to HSP90 triggers conformation change (Saccharomyces cerevisiae)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
ATP hydrolysis by HSP70 (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
Unfolded Protein Response (UPR) (Saccharomyces cerevisiae)
IRE1alpha activates chaperones (Saccharomyces cerevisiae)
IRE1 dimer autophosphorylates (Saccharomyces cerevisiae)
ADP [cytosol]
Developmental Biology (Saccharomyces cerevisiae)
Nervous system development (Saccharomyces cerevisiae)
Axon guidance (Saccharomyces cerevisiae)
L1CAM interactions (Saccharomyces cerevisiae)
Recycling pathway of L1 (Saccharomyces cerevisiae)
Phosphorylation of L1 by ERK (Saccharomyces cerevisiae)
ADP [cytosol]
Signal transduction by L1 (Saccharomyces cerevisiae)
MAP2K1 phosphorylates MAPK3 (Saccharomyces cerevisiae)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Saccharomyces cerevisiae)
ADP [cytosol]
Drug ADME (Saccharomyces cerevisiae)
Aspirin ADME (Saccharomyces cerevisiae)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Saccharomyces cerevisiae)
ADP [cytosol]
Azathioprine ADME (Saccharomyces cerevisiae)
GUK1 phosphorylates 6TGMP to 6TGDP (Saccharomyces cerevisiae)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Saccharomyces cerevisiae)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Saccharomyces cerevisiae)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Saccharomyces cerevisiae)
ADP [cytosol]
Ciprofloxacin ADME (Saccharomyces cerevisiae)
ABCG2 transports Cipro from hepatic cell to extracellular space (Saccharomyces cerevisiae)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Saccharomyces cerevisiae)
ADP [cytosol]
Paracetamol ADME (Saccharomyces cerevisiae)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)
ADP [cytosol]
Ribavirin ADME (Saccharomyces cerevisiae)
ADK phosphorylates RBV (Saccharomyces cerevisiae)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Saccharomyces cerevisiae)
ADP [cytosol]
Gene expression (Transcription) (Saccharomyces cerevisiae)
RNA Polymerase II Transcription (Saccharomyces cerevisiae)
Generic Transcription Pathway (Saccharomyces cerevisiae)
Transcriptional Regulation by TP53 (Saccharomyces cerevisiae)
Regulation of TP53 Activity (Saccharomyces cerevisiae)
Regulation of TP53 Expression and Degradation (Saccharomyces cerevisiae)
Regulation of TP53 Degradation (Saccharomyces cerevisiae)
PDPK1 phosphorylates SGK1 (Saccharomyces cerevisiae)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Saccharomyces cerevisiae)
ADP [cytosol]
Hemostasis (Saccharomyces cerevisiae)
Platelet activation, signaling and aggregation (Saccharomyces cerevisiae)
Response to elevated platelet cytosolic Ca2+ (Saccharomyces cerevisiae)
Disinhibition of SNARE formation (Saccharomyces cerevisiae)
Phosphorylation of Platelet Sec-1 (Saccharomyces cerevisiae)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Saccharomyces cerevisiae)
ADP [cytosol]
Signal amplification (Saccharomyces cerevisiae)
ADP signalling through P2Y purinoceptor 1 (Saccharomyces cerevisiae)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Saccharomyces cerevisiae)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Saccharomyces cerevisiae)
ADP [cytosol]
Platelet homeostasis (Saccharomyces cerevisiae)
Platelet sensitization by LDL (Saccharomyces cerevisiae)
Phosphorylation of cPLA2 by MAPK p38 alpha (Saccharomyces cerevisiae)
ADP [cytosol]
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Costimulation by the CD28 family (Saccharomyces cerevisiae)
CD28 co-stimulation (Saccharomyces cerevisiae)
CD28 dependent PI3K/Akt signaling (Saccharomyces cerevisiae)
AKT interacts and phosphorylates Cot (Saccharomyces cerevisiae)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Saccharomyces cerevisiae)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Saccharomyces cerevisiae)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Saccharomyces cerevisiae)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Saccharomyces cerevisiae)
ADP [cytosol]
TCR signaling (Saccharomyces cerevisiae)
Downstream TCR signaling (Saccharomyces cerevisiae)
Phosphorylation of PKC theta (Saccharomyces cerevisiae)
ADP [cytosol]
Cytokine Signaling in Immune system (Saccharomyces cerevisiae)
Signaling by Interleukins (Saccharomyces cerevisiae)
Interleukin-1 family signaling (Saccharomyces cerevisiae)
Interleukin-38 signaling (Saccharomyces cerevisiae)
MAPK8 phosphorylation (Saccharomyces cerevisiae)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Saccharomyces cerevisiae)
NIK-->noncanonical NF-kB signaling (Saccharomyces cerevisiae)
NIK autophosphorylates on T559 (Saccharomyces cerevisiae)
ADP [cytosol]
Innate Immune System (Saccharomyces cerevisiae)
Fc epsilon receptor (FCERI) signaling (Saccharomyces cerevisiae)
FCERI mediated NF-kB activation (Saccharomyces cerevisiae)
Autophosphorylation of PKC-theta (Saccharomyces cerevisiae)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Saccharomyces cerevisiae)
Regulation of actin dynamics for phagocytic cup formation (Saccharomyces cerevisiae)
Autophosphorylation of PAK1 (Saccharomyces cerevisiae)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Saccharomyces cerevisiae)
Mother filament:ARP2/3:actin:ADP [cytosol] (Saccharomyces cerevisiae)
Actin:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
Role of phospholipids in phagocytosis (Saccharomyces cerevisiae)
DAG stimulates protein kinase C-delta (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Pyruvate metabolism (Saccharomyces cerevisiae)
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
ADP [cytosol]
Biological oxidations (Saccharomyces cerevisiae)
Phase II - Conjugation of compounds (Saccharomyces cerevisiae)
Cytosolic sulfonation of small molecules (Saccharomyces cerevisiae)
Transport and synthesis of PAPS (Saccharomyces cerevisiae)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Saccharomyces cerevisiae)
ADP [cytosol]
Glutathione conjugation (Saccharomyces cerevisiae)
Glutathione synthesis and recycling (Saccharomyces cerevisiae)
GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Saccharomyces cerevisiae)
ADP [cytosol]
Inositol phosphate metabolism (Saccharomyces cerevisiae)
Synthesis of pyrophosphates in the cytosol (Saccharomyces cerevisiae)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Glutamate and glutamine metabolism (Saccharomyces cerevisiae)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of carbohydrates (Saccharomyces cerevisiae)
Formation of xylulose-5-phosphate (Saccharomyces cerevisiae)
XYLB phosphorylates D-xylulose (Saccharomyces cerevisiae)
ADP [cytosol]
Fructose metabolism (Saccharomyces cerevisiae)
Fructose catabolism (Saccharomyces cerevisiae)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Saccharomyces cerevisiae)
ADP [cytosol]
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Saccharomyces cerevisiae)
ADP [cytosol]
Glycolysis (Saccharomyces cerevisiae)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Saccharomyces cerevisiae)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Saccharomyces cerevisiae)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Saccharomyces cerevisiae)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Saccharomyces cerevisiae)
ADP [cytosol]
Glycosaminoglycan metabolism (Saccharomyces cerevisiae)
Transport and synthesis of PAPS (Saccharomyces cerevisiae)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Saccharomyces cerevisiae)
ADP [cytosol]
Pentose phosphate pathway (Saccharomyces cerevisiae)
RBKS phosphorylates ribose to R5P (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Carnitine metabolism (Saccharomyces cerevisiae)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Saccharomyces cerevisiae)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Saccharomyces cerevisiae)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of steroids (Saccharomyces cerevisiae)
Bile acid and bile salt metabolism (Saccharomyces cerevisiae)
Recycling of bile acids and salts (Saccharomyces cerevisiae)
ABCC3 transports bile salts from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
Cholesterol biosynthesis (Saccharomyces cerevisiae)
MVD decarboxylates MVA5PP to IPPP (Saccharomyces cerevisiae)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Saccharomyces cerevisiae)
ADP [cytosol]
Phospholipid metabolism (Saccharomyces cerevisiae)
Glycerophospholipid biosynthesis (Saccharomyces cerevisiae)
Synthesis of PC (Saccharomyces cerevisiae)
Cho is phosphorylated to PCho by CHK dimer (Saccharomyces cerevisiae)
ADP [cytosol]
Synthesis of PE (Saccharomyces cerevisiae)
ETA is phosphorylated to PETA by CHK/ETNK (Saccharomyces cerevisiae)
ADP [cytosol]
PI Metabolism (Saccharomyces cerevisiae)
Synthesis of PIPs at the ER membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Sphingolipid metabolism (Saccharomyces cerevisiae)
Sphingolipid de novo biosynthesis (Saccharomyces cerevisiae)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Saccharomyces cerevisiae)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Saccharomyces cerevisiae)
ADP [cytosol]
Triglyceride metabolism (Saccharomyces cerevisiae)
Triglyceride biosynthesis (Saccharomyces cerevisiae)
Conversion of Glycerol to Glycerol-3-phosphate (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Saccharomyces cerevisiae)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Saccharomyces cerevisiae)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Saccharomyces cerevisiae)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Saccharomyces cerevisiae)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Saccharomyces cerevisiae)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Saccharomyces cerevisiae)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Saccharomyces cerevisiae)
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Saccharomyces cerevisiae)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Saccharomyces cerevisiae)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Saccharomyces cerevisiae)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Saccharomyces cerevisiae)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Saccharomyces cerevisiae)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Saccharomyces cerevisiae)
ADP [cytosol]
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Saccharomyces cerevisiae)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Saccharomyces cerevisiae)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Saccharomyces cerevisiae)
ADP [cytosol]
Pyrimidine biosynthesis (Saccharomyces cerevisiae)
CAD hexamer transforms L-Gln to CAP (Saccharomyces cerevisiae)
ADP [cytosol]
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Saccharomyces cerevisiae)
ADP [cytosol]
Pyrimidine salvage (Saccharomyces cerevisiae)
UCKL1 phosphorylates urindine, cytidine (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of porphyrins (Saccharomyces cerevisiae)
Heme biosynthesis (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
Heme degradation (Saccharomyces cerevisiae)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Saccharomyces cerevisiae)
Transport of RCbl within the body (Saccharomyces cerevisiae)
ABCC1 transports cytosolic RCbl to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of folate and pterines (Saccharomyces cerevisiae)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Saccharomyces cerevisiae)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Saccharomyces cerevisiae)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Saccharomyces cerevisiae)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)
ADP [cytosol]
Nicotinate metabolism (Saccharomyces cerevisiae)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Saccharomyces cerevisiae)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Saccharomyces cerevisiae)
RFK:Mg2+ phosphorylates RIB (Saccharomyces cerevisiae)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Saccharomyces cerevisiae)
Coenzyme A biosynthesis (Saccharomyces cerevisiae)
COASY phosphorylates DP-CoA (Saccharomyces cerevisiae)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Saccharomyces cerevisiae)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Saccharomyces cerevisiae)
2xPDKX:2xZn2+ phosphorylates PDX (Saccharomyces cerevisiae)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Saccharomyces cerevisiae)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of RNA (Saccharomyces cerevisiae)
Nonsense-Mediated Decay (NMD) (Saccharomyces cerevisiae)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Saccharomyces cerevisiae)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Saccharomyces cerevisiae)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Saccharomyces cerevisiae)
Protein Kinase B/Akt phosphorylates BRF1 (Saccharomyces cerevisiae)
ADP [cytosol]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
Synthesis of substrates in N-glycan biosythesis (Saccharomyces cerevisiae)
Synthesis of Dolichyl-phosphate (Saccharomyces cerevisiae)
MVD decarboxylates MVA5PP to IPPP (Saccharomyces cerevisiae)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Saccharomyces cerevisiae)
ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
COPI-mediated anterograde transport (Saccharomyces cerevisiae)
GBF1 stimulates ARF nucleotide exchange (Saccharomyces cerevisiae)
ADP [cytosol]
COPII-mediated vesicle transport (Saccharomyces cerevisiae)
CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)
ADP [cytosol]
Protein folding (Saccharomyces cerevisiae)
Chaperonin-mediated protein folding (Saccharomyces cerevisiae)
Association of TriC/CCT with target proteins during biosynthesis (Saccharomyces cerevisiae)
Association of CCT/TriC with sphingosine kinase 1 (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Saccharomyces cerevisiae)
ATP binds G-protein beta associated TRiC/CCT (Saccharomyces cerevisiae)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Saccharomyces cerevisiae)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
Translation (Saccharomyces cerevisiae)
Eukaryotic Translation Initiation (Saccharomyces cerevisiae)
Cap-dependent Translation Initiation (Saccharomyces cerevisiae)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Saccharomyces cerevisiae)
Cap-bound mRNA is activated by helicases (Saccharomyces cerevisiae)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Saccharomyces cerevisiae)
Ribosomal scanning (Saccharomyces cerevisiae)
ADP [cytosol]
Neuronal System (Saccharomyces cerevisiae)
Transmission across Chemical Synapses (Saccharomyces cerevisiae)
Neurotransmitter uptake and metabolism In glial cells (Saccharomyces cerevisiae)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Saccharomyces cerevisiae)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Saccharomyces cerevisiae)
ADP [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Intracellular signaling by second messengers (Saccharomyces cerevisiae)
DAG and IP3 signaling (Saccharomyces cerevisiae)
DAG stimulates protein kinase C-delta (Saccharomyces cerevisiae)
ADP [cytosol]
PIP3 activates AKT signaling (Saccharomyces cerevisiae)
Negative regulation of the PI3K/AKT network (Saccharomyces cerevisiae)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Saccharomyces cerevisiae)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Saccharomyces cerevisiae)
ADP [cytosol]
PTEN Regulation (Saccharomyces cerevisiae)
Regulation of PTEN stability and activity (Saccharomyces cerevisiae)
Casein kinase II phosphorylates PTEN (Saccharomyces cerevisiae)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Saccharomyces cerevisiae)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Saccharomyces cerevisiae)
ADP [cytosol]
MAPK family signaling cascades (Saccharomyces cerevisiae)
MAPK1/MAPK3 signaling (Saccharomyces cerevisiae)
RAF-independent MAPK1/3 activation (Saccharomyces cerevisiae)
MAPK1 (ERK2) activation (Saccharomyces cerevisiae)
MAP2K2 phosphorylates MAPK1 (Saccharomyces cerevisiae)
ADP [cytosol]
MAPK3 (ERK1) activation (Saccharomyces cerevisiae)
MAP2K1 phosphorylates MAPK3 (Saccharomyces cerevisiae)
ADP [cytosol]
RAF/MAP kinase cascade (Saccharomyces cerevisiae)
MAP2K and MAPK activation (Saccharomyces cerevisiae)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Negative regulation of MAPK pathway (Saccharomyces cerevisiae)
Negative feedback regulation of MAPK pathway (Saccharomyces cerevisiae)
Activated MAPKs phosphorylate MAP2K1 (Saccharomyces cerevisiae)
ADP [cytosol]
MAPK6/MAPK4 signaling (Saccharomyces cerevisiae)
Autophosphorylation of PAK1,2,3 (Saccharomyces cerevisiae)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Saccharomyces cerevisiae)
ADP [cytosol]
MTOR signalling (Saccharomyces cerevisiae)
mTORC1-mediated signalling (Saccharomyces cerevisiae)
Phosphorylation and activation of eIF4B by activated S6K1 (Saccharomyces cerevisiae)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Saccharomyces cerevisiae)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by GPCR (Saccharomyces cerevisiae)
GPCR downstream signalling (Saccharomyces cerevisiae)
G alpha (i) signalling events (Saccharomyces cerevisiae)
Opioid Signalling (Saccharomyces cerevisiae)
G-protein mediated events (Saccharomyces cerevisiae)
PLC beta mediated events (Saccharomyces cerevisiae)
Ca-dependent events (Saccharomyces cerevisiae)
phospho-PLA2 pathway (Saccharomyces cerevisiae)
Phosphorylation of cPLA2 by ERK-2 (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
Estrogen-stimulated signaling through PRKCZ (Saccharomyces cerevisiae)
PRKCZ autophosphorylates downstream of estrogen stimulation (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by Insulin receptor (Saccharomyces cerevisiae)
Insulin receptor signalling cascade (Saccharomyces cerevisiae)
IRS-mediated signalling (Saccharomyces cerevisiae)
PI3K Cascade (Saccharomyces cerevisiae)
Activation of AKT2 (Saccharomyces cerevisiae)
PDPK1 phosphorylates AKT2 (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Saccharomyces cerevisiae)
IGF1R signaling cascade (Saccharomyces cerevisiae)
IRS-related events triggered by IGF1R (Saccharomyces cerevisiae)
IRS-mediated signalling (Saccharomyces cerevisiae)
PI3K Cascade (Saccharomyces cerevisiae)
Activation of AKT2 (Saccharomyces cerevisiae)
PDPK1 phosphorylates AKT2 (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated cell proliferation (Saccharomyces cerevisiae)
PDK1 phosphorylates PKC (Saccharomyces cerevisiae)
ADP [cytosol]
PKC autophosphorylates (Saccharomyces cerevisiae)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Saccharomyces cerevisiae)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Saccharomyces cerevisiae)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Saccharomyces cerevisiae)
Signaling by Rho GTPases (Saccharomyces cerevisiae)
RHO GTPase Effectors (Saccharomyces cerevisiae)
RHO GTPases Activate NADPH Oxidases (Saccharomyces cerevisiae)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Saccharomyces cerevisiae)
ADP [cytosol]
PKC phosphorylates NCF1 (Saccharomyces cerevisiae)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Saccharomyces cerevisiae)
Branching and elongation of mother and daughter filaments (Saccharomyces cerevisiae)
Mother filament:ARP2/3:actin:ADP [cytosol] (Saccharomyces cerevisiae)
Actin:ADP [cytosol] (Saccharomyces cerevisiae)
ADP [cytosol]
RHO GTPases activate PAKs (Saccharomyces cerevisiae)
Autophosphorylation of PAK1,2,3 (Saccharomyces cerevisiae)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Saccharomyces cerevisiae)
ADP [cytosol]
RHO GTPases activate PKNs (Saccharomyces cerevisiae)
PDPK1 phosphorylates PKN1,2,3 (Saccharomyces cerevisiae)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Saccharomyces cerevisiae)
ADP [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
ABC-family proteins mediated transport (Saccharomyces cerevisiae)
ABC transporters in lipid homeostasis (Saccharomyces cerevisiae)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Saccharomyces cerevisiae)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
The ABCC family mediates organic anion transport (Saccharomyces cerevisiae)
ADP [cytosol]
Ion channel transport (Saccharomyces cerevisiae)
Ion transport by P-type ATPases (Saccharomyces cerevisiae)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Saccharomyces cerevisiae)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Saccharomyces cerevisiae)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Saccharomyces cerevisiae)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Saccharomyces cerevisiae)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Saccharomyces cerevisiae)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Iron uptake and transport (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
ADP [cytosol]
Transferrin endocytosis and recycling (Saccharomyces cerevisiae)
Acidification of Tf:TfR1 containing endosome (Saccharomyces cerevisiae)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Saccharomyces cerevisiae)
Plasma lipoprotein remodeling (Saccharomyces cerevisiae)
HDL remodeling (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
ADP [cytosol]
SLC-mediated transmembrane transport (Saccharomyces cerevisiae)
Transport of vitamins, nucleosides, and related molecules (Saccharomyces cerevisiae)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Saccharomyces cerevisiae)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Vesicle-mediated transport (Saccharomyces cerevisiae)
Membrane Trafficking (Saccharomyces cerevisiae)
Clathrin-mediated endocytosis (Saccharomyces cerevisiae)
AAK1 phosphorylates AP-2 mu subunit at T156 (Saccharomyces cerevisiae)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Saccharomyces cerevisiae)
ADP [cytosol]
ER to Golgi Anterograde Transport (Saccharomyces cerevisiae)
COPI-mediated anterograde transport (Saccharomyces cerevisiae)
GBF1 stimulates ARF nucleotide exchange (Saccharomyces cerevisiae)
ADP [cytosol]
COPII-mediated vesicle transport (Saccharomyces cerevisiae)
CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Saccharomyces cerevisiae)
ESCRT Disassembly (Saccharomyces cerevisiae)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Saccharomyces cerevisiae)
Intra-Golgi traffic (Saccharomyces cerevisiae)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Saccharomyces cerevisiae)
ADP [cytosol]
Autophagy (Schizosaccharomyces pombe)
Macroautophagy (Schizosaccharomyces pombe)
AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Schizosaccharomyces pombe)
ADP [cytosol]
Selective autophagy (Schizosaccharomyces pombe)
Mitophagy (Schizosaccharomyces pombe)
Receptor Mediated Mitophagy (Schizosaccharomyces pombe)
FUNDC1 is phosphorylated by CK2 (Schizosaccharomyces pombe)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Schizosaccharomyces pombe)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Schizosaccharomyces pombe)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Schizosaccharomyces pombe)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Schizosaccharomyces pombe)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)
ADP [cytosol]
Cell Cycle (Schizosaccharomyces pombe)
Cell Cycle, Mitotic (Schizosaccharomyces pombe)
M Phase (Schizosaccharomyces pombe)
Mitotic Prometaphase (Schizosaccharomyces pombe)
Condensation of Prometaphase Chromosomes (Schizosaccharomyces pombe)
CK2 phosphorylates condensin I subunits (Schizosaccharomyces pombe)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Schizosaccharomyces pombe)
PLK1 phosphorylates NUDC (Schizosaccharomyces pombe)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Schizosaccharomyces pombe)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Schizosaccharomyces pombe)
ADP [cytosol]
Mitotic Prophase (Schizosaccharomyces pombe)
Golgi Cisternae Pericentriolar Stack Reorganization (Schizosaccharomyces pombe)
PLK1 phosphorylates GORASP1 (Schizosaccharomyces pombe)
ADP [cytosol]
Mitotic G2-G2/M phases (Schizosaccharomyces pombe)
G2/M Transition (Schizosaccharomyces pombe)
Polo-like kinase mediated events (Schizosaccharomyces pombe)
Activation of Cdc25C (Schizosaccharomyces pombe)
ADP [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Cellular response to chemical stress (Schizosaccharomyces pombe)
KEAP1-NFE2L2 pathway (Schizosaccharomyces pombe)
Nuclear events mediated by NFE2L2 (Schizosaccharomyces pombe)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Schizosaccharomyces pombe)
SRXN1 reduces hyperoxidized PRDX1 dimer (Schizosaccharomyces pombe)
ADP [cytosol]
Cellular response to heat stress (Schizosaccharomyces pombe)
Regulation of HSF1-mediated heat shock response (Schizosaccharomyces pombe)
Constitutive phosphorylation by pERK1/2 (Schizosaccharomyces pombe)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Schizosaccharomyces pombe)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Schizosaccharomyces pombe)
ADP [cytosol]
HSP70s:ADP [cytosol] (Schizosaccharomyces pombe)
HSP13:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP14:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA2:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA4:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA5:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA6:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA8:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA9:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Schizosaccharomyces pombe)
HSP70s:ADP [cytosol] (Schizosaccharomyces pombe)
HSP13:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP14:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA2:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA4:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA5:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA6:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA8:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSPA9:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Schizosaccharomyces pombe)
ATP binding to HSP90 triggers conformation change (Schizosaccharomyces pombe)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
ATP hydrolysis by HSP70 (Schizosaccharomyces pombe)
HSP40:HSP70:ADP:nascent protein [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Schizosaccharomyces pombe)
HSP40:HSP70:ADP:nascent protein [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
Unfolded Protein Response (UPR) (Schizosaccharomyces pombe)
IRE1alpha activates chaperones (Schizosaccharomyces pombe)
IRE1 dimer autophosphorylates (Schizosaccharomyces pombe)
ADP [cytosol]
DNA Replication (Schizosaccharomyces pombe)
DNA Replication Pre-Initiation (Schizosaccharomyces pombe)
Assembly of the pre-replicative complex (Schizosaccharomyces pombe)
Assembly of the ORC complex at the origin of replication (Schizosaccharomyces pombe)
ORC6 is phosphorylated on T195 (Schizosaccharomyces pombe)
ADP [cytosol]
Developmental Biology (Schizosaccharomyces pombe)
Nervous system development (Schizosaccharomyces pombe)
Axon guidance (Schizosaccharomyces pombe)
L1CAM interactions (Schizosaccharomyces pombe)
Recycling pathway of L1 (Schizosaccharomyces pombe)
Phosphorylation of L1 by ERK (Schizosaccharomyces pombe)
ADP [cytosol]
Signal transduction by L1 (Schizosaccharomyces pombe)
MAP2K1 phosphorylates MAPK3 (Schizosaccharomyces pombe)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Schizosaccharomyces pombe)
ADP [cytosol]
Drug ADME (Schizosaccharomyces pombe)
Aspirin ADME (Schizosaccharomyces pombe)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Schizosaccharomyces pombe)
ADP [cytosol]
Azathioprine ADME (Schizosaccharomyces pombe)
GUK1 phosphorylates 6TGMP to 6TGDP (Schizosaccharomyces pombe)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Schizosaccharomyces pombe)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Schizosaccharomyces pombe)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Schizosaccharomyces pombe)
ADP [cytosol]
Paracetamol ADME (Schizosaccharomyces pombe)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Schizosaccharomyces pombe)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Schizosaccharomyces pombe)
ADP [cytosol]
Prednisone ADME (Schizosaccharomyces pombe)
ABCB1 transports PREDN,PREDL out of hepatic cells (Schizosaccharomyces pombe)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Schizosaccharomyces pombe)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Schizosaccharomyces pombe)
ADP [cytosol]
Ribavirin ADME (Schizosaccharomyces pombe)
ADK phosphorylates RBV (Schizosaccharomyces pombe)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Schizosaccharomyces pombe)
ADP [cytosol]
Gene expression (Transcription) (Schizosaccharomyces pombe)
RNA Polymerase II Transcription (Schizosaccharomyces pombe)
Generic Transcription Pathway (Schizosaccharomyces pombe)
Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
Regulation of TP53 Activity (Schizosaccharomyces pombe)
Regulation of TP53 Expression and Degradation (Schizosaccharomyces pombe)
Regulation of TP53 Degradation (Schizosaccharomyces pombe)
PDPK1 phosphorylates SGK1 (Schizosaccharomyces pombe)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Schizosaccharomyces pombe)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Schizosaccharomyces pombe)
AKT phosphorylates TSC2, inhibiting it (Schizosaccharomyces pombe)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Schizosaccharomyces pombe)
ADP [cytosol]
Hemostasis (Schizosaccharomyces pombe)
Platelet activation, signaling and aggregation (Schizosaccharomyces pombe)
Response to elevated platelet cytosolic Ca2+ (Schizosaccharomyces pombe)
Disinhibition of SNARE formation (Schizosaccharomyces pombe)
Phosphorylation of Platelet Sec-1 (Schizosaccharomyces pombe)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Schizosaccharomyces pombe)
ADP [cytosol]
Signal amplification (Schizosaccharomyces pombe)
ADP signalling through P2Y purinoceptor 1 (Schizosaccharomyces pombe)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Schizosaccharomyces pombe)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Schizosaccharomyces pombe)
ADP [cytosol]
Platelet homeostasis (Schizosaccharomyces pombe)
Platelet sensitization by LDL (Schizosaccharomyces pombe)
Phosphorylation of cPLA2 by MAPK p38 alpha (Schizosaccharomyces pombe)
ADP [cytosol]
Immune System (Schizosaccharomyces pombe)
Adaptive Immune System (Schizosaccharomyces pombe)
Class I MHC mediated antigen processing & presentation (Schizosaccharomyces pombe)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Schizosaccharomyces pombe)
Transport of Antigen peptide in to ER (Schizosaccharomyces pombe)
ADP [cytosol]
Costimulation by the CD28 family (Schizosaccharomyces pombe)
CD28 co-stimulation (Schizosaccharomyces pombe)
CD28 dependent PI3K/Akt signaling (Schizosaccharomyces pombe)
TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Schizosaccharomyces pombe)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Schizosaccharomyces pombe)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Schizosaccharomyces pombe)
ADP [cytosol]
TCR signaling (Schizosaccharomyces pombe)
Downstream TCR signaling (Schizosaccharomyces pombe)
Phosphorylation of PKC theta (Schizosaccharomyces pombe)
ADP [cytosol]
Cytokine Signaling in Immune system (Schizosaccharomyces pombe)
Signaling by Interleukins (Schizosaccharomyces pombe)
Interleukin-1 family signaling (Schizosaccharomyces pombe)
Interleukin-38 signaling (Schizosaccharomyces pombe)
MAPK8 phosphorylation (Schizosaccharomyces pombe)
ADP [cytosol]
Innate Immune System (Schizosaccharomyces pombe)
Fc epsilon receptor (FCERI) signaling (Schizosaccharomyces pombe)
FCERI mediated NF-kB activation (Schizosaccharomyces pombe)
Autophosphorylation of PKC-theta (Schizosaccharomyces pombe)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Schizosaccharomyces pombe)
Regulation of actin dynamics for phagocytic cup formation (Schizosaccharomyces pombe)
Autophosphorylation of PAK1 (Schizosaccharomyces pombe)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Schizosaccharomyces pombe)
Mother filament:ARP2/3:actin:ADP [cytosol] (Schizosaccharomyces pombe)
Actin:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
Role of phospholipids in phagocytosis (Schizosaccharomyces pombe)
DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Pyruvate metabolism (Schizosaccharomyces pombe)
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
ADP [cytosol]
Biological oxidations (Schizosaccharomyces pombe)
Phase II - Conjugation of compounds (Schizosaccharomyces pombe)
Cytosolic sulfonation of small molecules (Schizosaccharomyces pombe)
Transport and synthesis of PAPS (Schizosaccharomyces pombe)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Schizosaccharomyces pombe)
ADP [cytosol]
Glutathione conjugation (Schizosaccharomyces pombe)
Glutathione synthesis and recycling (Schizosaccharomyces pombe)
GCL ligates L-Glu to L-Cys (Schizosaccharomyces pombe)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Schizosaccharomyces pombe)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Schizosaccharomyces pombe)
ADP [cytosol]
Inositol phosphate metabolism (Schizosaccharomyces pombe)
Synthesis of pyrophosphates in the cytosol (Schizosaccharomyces pombe)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Glutamate and glutamine metabolism (Schizosaccharomyces pombe)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of carbohydrates (Schizosaccharomyces pombe)
Formation of xylulose-5-phosphate (Schizosaccharomyces pombe)
XYLB phosphorylates D-xylulose (Schizosaccharomyces pombe)
ADP [cytosol]
Fructose metabolism (Schizosaccharomyces pombe)
Fructose catabolism (Schizosaccharomyces pombe)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Schizosaccharomyces pombe)
ADP [cytosol]
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Schizosaccharomyces pombe)
ADP [cytosol]
Glycolysis (Schizosaccharomyces pombe)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Schizosaccharomyces pombe)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Schizosaccharomyces pombe)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Schizosaccharomyces pombe)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Schizosaccharomyces pombe)
ADP [cytosol]
Glycosaminoglycan metabolism (Schizosaccharomyces pombe)
Transport and synthesis of PAPS (Schizosaccharomyces pombe)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Schizosaccharomyces pombe)
ADP [cytosol]
Pentose phosphate pathway (Schizosaccharomyces pombe)
RBKS phosphorylates ribose to R5P (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Carnitine metabolism (Schizosaccharomyces pombe)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Schizosaccharomyces pombe)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Schizosaccharomyces pombe)
ACLY tetramer transforms CIT to Ac-CoA (Schizosaccharomyces pombe)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of steroids (Schizosaccharomyces pombe)
Bile acid and bile salt metabolism (Schizosaccharomyces pombe)
Recycling of bile acids and salts (Schizosaccharomyces pombe)
ABCB11 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of bile acids and bile salts (Schizosaccharomyces pombe)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Schizosaccharomyces pombe)
ABCB11 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
Cholesterol biosynthesis (Schizosaccharomyces pombe)
MVD decarboxylates MVA5PP to IPPP (Schizosaccharomyces pombe)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)
ADP [cytosol]
Phospholipid metabolism (Schizosaccharomyces pombe)
Glycerophospholipid biosynthesis (Schizosaccharomyces pombe)
Synthesis of PC (Schizosaccharomyces pombe)
Cho is phosphorylated to PCho by CHK dimer (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of PE (Schizosaccharomyces pombe)
ETA is phosphorylated to PETA by CHK/ETNK (Schizosaccharomyces pombe)
ADP [cytosol]
PI Metabolism (Schizosaccharomyces pombe)
Synthesis of PIPs at the ER membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Sphingolipid metabolism (Schizosaccharomyces pombe)
Sphingolipid de novo biosynthesis (Schizosaccharomyces pombe)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Schizosaccharomyces pombe)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Schizosaccharomyces pombe)
eNOS activation (Schizosaccharomyces pombe)
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Schizosaccharomyces pombe)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Schizosaccharomyces pombe)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Schizosaccharomyces pombe)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Schizosaccharomyces pombe)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Schizosaccharomyces pombe)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Schizosaccharomyces pombe)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Schizosaccharomyces pombe)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Schizosaccharomyces pombe)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Schizosaccharomyces pombe)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Schizosaccharomyces pombe)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Schizosaccharomyces pombe)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Schizosaccharomyces pombe)
ADP [cytosol]
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Schizosaccharomyces pombe)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Schizosaccharomyces pombe)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Schizosaccharomyces pombe)
ADP [cytosol]
Pyrimidine biosynthesis (Schizosaccharomyces pombe)
CAD hexamer transforms L-Gln to CAP (Schizosaccharomyces pombe)
ADP [cytosol]
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Schizosaccharomyces pombe)
ADP [cytosol]
Pyrimidine salvage (Schizosaccharomyces pombe)
UCKL1 phosphorylates urindine, cytidine (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of porphyrins (Schizosaccharomyces pombe)
Heme degradation (Schizosaccharomyces pombe)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Schizosaccharomyces pombe)
Transport of RCbl within the body (Schizosaccharomyces pombe)
ABCC1 transports cytosolic RCbl to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of folate and pterines (Schizosaccharomyces pombe)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Schizosaccharomyces pombe)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Schizosaccharomyces pombe)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Schizosaccharomyces pombe)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Schizosaccharomyces pombe)
ADP [cytosol]
Nicotinate metabolism (Schizosaccharomyces pombe)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Schizosaccharomyces pombe)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Schizosaccharomyces pombe)
RFK:Mg2+ phosphorylates RIB (Schizosaccharomyces pombe)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Schizosaccharomyces pombe)
Coenzyme A biosynthesis (Schizosaccharomyces pombe)
COASY phosphorylates DP-CoA (Schizosaccharomyces pombe)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Schizosaccharomyces pombe)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Schizosaccharomyces pombe)
2xPDKX:2xZn2+ phosphorylates PDX (Schizosaccharomyces pombe)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Schizosaccharomyces pombe)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of RNA (Schizosaccharomyces pombe)
Nonsense-Mediated Decay (NMD) (Schizosaccharomyces pombe)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Schizosaccharomyces pombe)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Schizosaccharomyces pombe)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Schizosaccharomyces pombe)
Protein Kinase B/Akt phosphorylates BRF1 (Schizosaccharomyces pombe)
ADP [cytosol]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Schizosaccharomyces pombe)
Synthesis of substrates in N-glycan biosythesis (Schizosaccharomyces pombe)
Synthesis of Dolichyl-phosphate (Schizosaccharomyces pombe)
MVD decarboxylates MVA5PP to IPPP (Schizosaccharomyces pombe)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Schizosaccharomyces pombe)
ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
COPI-mediated anterograde transport (Schizosaccharomyces pombe)
GBF1 stimulates ARF nucleotide exchange (Schizosaccharomyces pombe)
ADP [cytosol]
COPII-mediated vesicle transport (Schizosaccharomyces pombe)
CSNK1D phosphorylates SEC23 (Schizosaccharomyces pombe)
ADP [cytosol]
Protein folding (Schizosaccharomyces pombe)
Chaperonin-mediated protein folding (Schizosaccharomyces pombe)
Association of TriC/CCT with target proteins during biosynthesis (Schizosaccharomyces pombe)
Association of CCT/TriC with sphingosine kinase 1 (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Schizosaccharomyces pombe)
ATP binds G-protein beta associated TRiC/CCT (Schizosaccharomyces pombe)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Schizosaccharomyces pombe)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
Translation (Schizosaccharomyces pombe)
Eukaryotic Translation Initiation (Schizosaccharomyces pombe)
Cap-dependent Translation Initiation (Schizosaccharomyces pombe)
Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S (Schizosaccharomyces pombe)
Cap-bound mRNA is activated by helicases (Schizosaccharomyces pombe)
ADP [cytosol]
Ribosomal scanning and start codon recognition (Schizosaccharomyces pombe)
Ribosomal scanning (Schizosaccharomyces pombe)
ADP [cytosol]
Neuronal System (Schizosaccharomyces pombe)
Transmission across Chemical Synapses (Schizosaccharomyces pombe)
Neurotransmitter receptors and postsynaptic signal transmission (Schizosaccharomyces pombe)
Activation of NMDA receptors and postsynaptic events (Schizosaccharomyces pombe)
Post NMDA receptor activation events (Schizosaccharomyces pombe)
Activation of RAC1 downstream of NMDARs (Schizosaccharomyces pombe)
CaMKK autophosphorylates in the cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Schizosaccharomyces pombe)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Schizosaccharomyces pombe)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Schizosaccharomyces pombe)
ADP [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
Intracellular signaling by second messengers (Schizosaccharomyces pombe)
DAG and IP3 signaling (Schizosaccharomyces pombe)
DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)
ADP [cytosol]
PIP3 activates AKT signaling (Schizosaccharomyces pombe)
AKT phosphorylates targets in the cytosol (Schizosaccharomyces pombe)
AKT phosphorylates MKRN1 (Schizosaccharomyces pombe)
ADP [cytosol]
AKT phosphorylates TSC2, inhibiting it (Schizosaccharomyces pombe)
ADP [cytosol]
Negative regulation of the PI3K/AKT network (Schizosaccharomyces pombe)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Schizosaccharomyces pombe)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Schizosaccharomyces pombe)
ADP [cytosol]
PTEN Regulation (Schizosaccharomyces pombe)
Regulation of PTEN stability and activity (Schizosaccharomyces pombe)
AKT phosphorylates MKRN1 (Schizosaccharomyces pombe)
ADP [cytosol]
Casein kinase II phosphorylates PTEN (Schizosaccharomyces pombe)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Schizosaccharomyces pombe)
ADP [cytosol]
MAPK family signaling cascades (Schizosaccharomyces pombe)
MAPK1/MAPK3 signaling (Schizosaccharomyces pombe)
RAF-independent MAPK1/3 activation (Schizosaccharomyces pombe)
MAPK1 (ERK2) activation (Schizosaccharomyces pombe)
MAP2K2 phosphorylates MAPK1 (Schizosaccharomyces pombe)
ADP [cytosol]
MAPK3 (ERK1) activation (Schizosaccharomyces pombe)
MAP2K1 phosphorylates MAPK3 (Schizosaccharomyces pombe)
ADP [cytosol]
RAF/MAP kinase cascade (Schizosaccharomyces pombe)
MAP2K and MAPK activation (Schizosaccharomyces pombe)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Negative regulation of MAPK pathway (Schizosaccharomyces pombe)
Negative feedback regulation of MAPK pathway (Schizosaccharomyces pombe)
Activated MAPKs phosphorylate MAP2K1 (Schizosaccharomyces pombe)
ADP [cytosol]
MAPK6/MAPK4 signaling (Schizosaccharomyces pombe)
Autophosphorylation of PAK1,2,3 (Schizosaccharomyces pombe)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Schizosaccharomyces pombe)
ADP [cytosol]
MTOR signalling (Schizosaccharomyces pombe)
Energy dependent regulation of mTOR by LKB1-AMPK (Schizosaccharomyces pombe)
p-AMPK phosphorylates TSC1:TSC2 (Schizosaccharomyces pombe)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Schizosaccharomyces pombe)
Phosphorylation of TSC2 by PKB (Schizosaccharomyces pombe)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Schizosaccharomyces pombe)
ADP [cytosol]
mTORC1-mediated signalling (Schizosaccharomyces pombe)
Phosphorylation and activation of eIF4B by activated S6K1 (Schizosaccharomyces pombe)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Schizosaccharomyces pombe)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by GPCR (Schizosaccharomyces pombe)
GPCR downstream signalling (Schizosaccharomyces pombe)
G alpha (i) signalling events (Schizosaccharomyces pombe)
Opioid Signalling (Schizosaccharomyces pombe)
G-protein mediated events (Schizosaccharomyces pombe)
PLC beta mediated events (Schizosaccharomyces pombe)
Ca-dependent events (Schizosaccharomyces pombe)
phospho-PLA2 pathway (Schizosaccharomyces pombe)
Phosphorylation of cPLA2 by ERK-2 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Extra-nuclear estrogen signaling (Schizosaccharomyces pombe)
Estrogen-stimulated signaling through PRKCZ (Schizosaccharomyces pombe)
PRKCZ autophosphorylates downstream of estrogen stimulation (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
Signaling by ERBB2 (Schizosaccharomyces pombe)
Downregulation of ERBB2 signaling (Schizosaccharomyces pombe)
Downregulation of ERBB2:ERBB3 signaling (Schizosaccharomyces pombe)
Phosphorylation of USP8 by P-AKT (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by Insulin receptor (Schizosaccharomyces pombe)
Insulin receptor signalling cascade (Schizosaccharomyces pombe)
IRS-mediated signalling (Schizosaccharomyces pombe)
PI3K Cascade (Schizosaccharomyces pombe)
Activation of AKT2 (Schizosaccharomyces pombe)
PDPK1 phosphorylates AKT2 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Schizosaccharomyces pombe)
IGF1R signaling cascade (Schizosaccharomyces pombe)
IRS-related events triggered by IGF1R (Schizosaccharomyces pombe)
IRS-mediated signalling (Schizosaccharomyces pombe)
PI3K Cascade (Schizosaccharomyces pombe)
Activation of AKT2 (Schizosaccharomyces pombe)
PDPK1 phosphorylates AKT2 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by VEGF (Schizosaccharomyces pombe)
VEGFA-VEGFR2 Pathway (Schizosaccharomyces pombe)
VEGFR2 mediated cell proliferation (Schizosaccharomyces pombe)
PDK1 phosphorylates PKC (Schizosaccharomyces pombe)
ADP [cytosol]
PKC autophosphorylates (Schizosaccharomyces pombe)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Schizosaccharomyces pombe)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Schizosaccharomyces pombe)
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
ADP [cytosol]
TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Schizosaccharomyces pombe)
Signaling by Rho GTPases (Schizosaccharomyces pombe)
RHO GTPase Effectors (Schizosaccharomyces pombe)
RHO GTPases Activate NADPH Oxidases (Schizosaccharomyces pombe)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Schizosaccharomyces pombe)
ADP [cytosol]
PKC phosphorylates NCF1 (Schizosaccharomyces pombe)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Schizosaccharomyces pombe)
Branching and elongation of mother and daughter filaments (Schizosaccharomyces pombe)
Mother filament:ARP2/3:actin:ADP [cytosol] (Schizosaccharomyces pombe)
Actin:ADP [cytosol] (Schizosaccharomyces pombe)
ADP [cytosol]
RHO GTPases activate PAKs (Schizosaccharomyces pombe)
Autophosphorylation of PAK1,2,3 (Schizosaccharomyces pombe)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Schizosaccharomyces pombe)
ADP [cytosol]
RHO GTPases activate PKNs (Schizosaccharomyces pombe)
PDPK1 phosphorylates PKN1,2,3 (Schizosaccharomyces pombe)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Schizosaccharomyces pombe)
ADP [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
ABC-family proteins mediated transport (Schizosaccharomyces pombe)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Schizosaccharomyces pombe)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Schizosaccharomyces pombe)
ADP [cytosol]
Mitochondrial ABC transporters (Schizosaccharomyces pombe)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Schizosaccharomyces pombe)
ADP [cytosol]
The ABCC family mediates organic anion transport (Schizosaccharomyces pombe)
ADP [cytosol]
Ion channel transport (Schizosaccharomyces pombe)
Ion transport by P-type ATPases (Schizosaccharomyces pombe)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Schizosaccharomyces pombe)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Schizosaccharomyces pombe)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Schizosaccharomyces pombe)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Schizosaccharomyces pombe)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Iron uptake and transport (Schizosaccharomyces pombe)
Transferrin endocytosis and recycling (Schizosaccharomyces pombe)
Acidification of Tf:TfR1 containing endosome (Schizosaccharomyces pombe)
ADP [cytosol]
SLC-mediated transmembrane transport (Schizosaccharomyces pombe)
Transport of vitamins, nucleosides, and related molecules (Schizosaccharomyces pombe)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Schizosaccharomyces pombe)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Vesicle-mediated transport (Schizosaccharomyces pombe)
Membrane Trafficking (Schizosaccharomyces pombe)
Clathrin-mediated endocytosis (Schizosaccharomyces pombe)
AAK1 phosphorylates AP-2 mu subunit at T156 (Schizosaccharomyces pombe)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Schizosaccharomyces pombe)
ADP [cytosol]
ER to Golgi Anterograde Transport (Schizosaccharomyces pombe)
COPI-mediated anterograde transport (Schizosaccharomyces pombe)
GBF1 stimulates ARF nucleotide exchange (Schizosaccharomyces pombe)
ADP [cytosol]
COPII-mediated vesicle transport (Schizosaccharomyces pombe)
CSNK1D phosphorylates SEC23 (Schizosaccharomyces pombe)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Schizosaccharomyces pombe)
ESCRT Disassembly (Schizosaccharomyces pombe)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Schizosaccharomyces pombe)
Intra-Golgi traffic (Schizosaccharomyces pombe)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Schizosaccharomyces pombe)
ADP [cytosol]
Rab regulation of trafficking (Schizosaccharomyces pombe)
RAB GEFs exchange GTP for GDP on RABs (Schizosaccharomyces pombe)
p-ULK1 phosphorylates DENND3 (Schizosaccharomyces pombe)
ADP [cytosol]
Autophagy (Sus scrofa)
Macroautophagy (Sus scrofa)
AMPK (complex) phosphorylates ULK1 (complex) (Sus scrofa)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Sus scrofa)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Sus scrofa)
ADP [cytosol]
Selective autophagy (Sus scrofa)
Mitophagy (Sus scrofa)
Receptor Mediated Mitophagy (Sus scrofa)
FUNDC1 is phosphorylated by CK2 (Sus scrofa)
ADP [cytosol]
FUNDC1 is phosphorylated by ULK1 at Ser17 (Sus scrofa)
ADP [cytosol]
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Sus scrofa)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Sus scrofa)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Sus scrofa)
ADP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)
ADP [cytosol]
Cell Cycle (Sus scrofa)
Cell Cycle Checkpoints (Sus scrofa)
G2/M Checkpoints (Sus scrofa)
G2/M DNA replication checkpoint (Sus scrofa)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Sus scrofa)
ADP [cytosol]
Cell Cycle, Mitotic (Sus scrofa)
M Phase (Sus scrofa)
Mitotic Metaphase and Anaphase (Sus scrofa)
Mitotic Anaphase (Sus scrofa)
Nuclear Envelope (NE) Reassembly (Sus scrofa)
Initiation of Nuclear Envelope (NE) Reformation (Sus scrofa)
CDK1 phosphorylates LBR (Sus scrofa)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Sus scrofa)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Sus scrofa)
ADP [cytosol]
Mitotic Prometaphase (Sus scrofa)
Condensation of Prometaphase Chromosomes (Sus scrofa)
CK2 phosphorylates condensin I subunits (Sus scrofa)
ADP [cytosol]
EML4 and NUDC in mitotic spindle formation (Sus scrofa)
NEK6 and NEK7 phosphorylate EML4 (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates NUDC (Sus scrofa)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Sus scrofa)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates FIRMM at S744 (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates FIRRM at S43 (Sus scrofa)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Sus scrofa)
ADP [cytosol]
Mitotic Prophase (Sus scrofa)
Golgi Cisternae Pericentriolar Stack Reorganization (Sus scrofa)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Sus scrofa)
ADP [cytosol]
Nuclear Envelope Breakdown (Sus scrofa)
Activation of NIMA Kinases NEK9, NEK6, NEK7 (Sus scrofa)
CDK1:CCNB phosphorylates NEK9 (Sus scrofa)
ADP [cytosol]
NEK9 phosphorylates NEK6/NEK7 (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates NEK9 (Sus scrofa)
ADP [cytosol]
Nuclear Pore Complex (NPC) Disassembly (Sus scrofa)
CDK1 phosphorylates NUP98 (Sus scrofa)
ADP [cytosol]
NEK6/NEK7 phosphorylates NUP98 (Sus scrofa)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Sus scrofa)
G1 Phase (Sus scrofa)
Cyclin D associated events in G1 (Sus scrofa)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Sus scrofa)
ADP [cytosol]
G1/S Transition (Sus scrofa)
Cyclin E associated events during G1/S transition (Sus scrofa)
SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
PTK6 phosphorylates CDKN1B (Sus scrofa)
ADP [cytosol]
Mitotic G2-G2/M phases (Sus scrofa)
G2/M Transition (Sus scrofa)
AURKA Activation by TPX2 (Sus scrofa)
TPX2 promotes AURKA autophosphorylation (Sus scrofa)
ADP [cytosol]
Centrosome maturation (Sus scrofa)
Loss of proteins required for interphase microtubule organization from the centrosome (Sus scrofa)
Loss of Nlp from mitotic centrosomes (Sus scrofa)
Plk1-mediated phosphorylation of Nlp (Sus scrofa)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Sus scrofa)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Sus scrofa)
ADP [cytosol]
Phosphorylation of Cyclin B1 in the CRS domain (Sus scrofa)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Sus scrofa)
AURKA phosphorylates PHLDA1 (Sus scrofa)
ADP [cytosol]
Polo-like kinase mediated events (Sus scrofa)
Activation of Cdc25C (Sus scrofa)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Sus scrofa)
AJUBA facilitates AURKA autophosphorylation (Sus scrofa)
ADP [cytosol]
AURKA phosphorylates PLK1 (Sus scrofa)
ADP [cytosol]
CDK1 phosphorylates BORA (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates BORA (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates OPTN (Sus scrofa)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Sus scrofa)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Sus scrofa)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Sus scrofa)
ADP [cytosol]
S Phase (Sus scrofa)
Cyclin A:Cdk2-associated events at S phase entry (Sus scrofa)
SCF(Skp2)-mediated degradation of p27/p21 (Sus scrofa)
PTK6 phosphorylates CDKN1B (Sus scrofa)
ADP [cytosol]
Cell-Cell communication (Sus scrofa)
Nephrin family interactions (Sus scrofa)
Phosphorylation of nephrin by FYN (Sus scrofa)
ADP [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular Senescence (Sus scrofa)
Oxidative Stress Induced Senescence (Sus scrofa)
MAP3K5 phosphorylates MKK3 and MKK6 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Cellular response to chemical stress (Sus scrofa)
KEAP1-NFE2L2 pathway (Sus scrofa)
Nuclear events mediated by NFE2L2 (Sus scrofa)
NFE2L2 regulating anti-oxidant/detoxification enzymes (Sus scrofa)
SRXN1 reduces hyperoxidized PRDX1 dimer (Sus scrofa)
ADP [cytosol]
PRKCI phosphorylates NFE2L2 (Sus scrofa)
ADP [cytosol]
Cellular response to heat stress (Sus scrofa)
Regulation of HSF1-mediated heat shock response (Sus scrofa)
Constitutive phosphorylation by pERK1/2 (Sus scrofa)
ADP [cytosol]
Constitutive phosphorylation by GSK3 (Sus scrofa)
ADP [cytosol]
HSP110s exchange ATP for ADP on HSP70s:ADP (Sus scrofa)
ADP [cytosol]
HSP70s:ADP [cytosol] (Sus scrofa)
HSP13:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP14:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA4:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA5:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA6:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA8:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA9:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Sus scrofa)
HSP70s:ADP [cytosol] (Sus scrofa)
HSP13:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP14:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA4:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA4L:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA5:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA6:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA8:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSPA9:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
MAPKAPK2 phosphorylates HSF1 (Sus scrofa)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Sus scrofa)
ATP binding to HSP90 triggers conformation change (Sus scrofa)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
ATP hydrolysis by HSP70 (Sus scrofa)
HSP40:HSP70:ADP:nascent protein [cytosol] (Sus scrofa)
ADP [cytosol]
FKBP4 binds HSP90:ATP:STIP1:HSP70:nascent protein (Sus scrofa)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
FKBP5 binds HSP90:ATP:STIP1:HSP70:nascent protein (Sus scrofa)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Sus scrofa)
HSP40:HSP70:ADP:nascent protein [cytosol] (Sus scrofa)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP4:nascent protein (Sus scrofa)
HSP90:ATP:FKBP4:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p23 (PTGES3) binds HSP90:ATP:FKBP5:nascent protein (Sus scrofa)
HSP90:ATP:FKBP5:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Unfolded Protein Response (UPR) (Sus scrofa)
PERK regulates gene expression (Sus scrofa)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Sus scrofa)
ADP [cytosol]
DNA Replication (Sus scrofa)
DNA Replication Pre-Initiation (Sus scrofa)
Assembly of the pre-replicative complex (Sus scrofa)
Assembly of the ORC complex at the origin of replication (Sus scrofa)
ORC6 is phosphorylated on T195 (Sus scrofa)
ADP [cytosol]
Developmental Biology (Sus scrofa)
MITF-M-regulated melanocyte development (Sus scrofa)
Transcriptional and post-translational regulation of MITF-M expression and activity (Sus scrofa)
MAPK-dependent phosphorylation of KARS (Sus scrofa)
ADP [cytosol]
Nervous system development (Sus scrofa)
Axon guidance (Sus scrofa)
EPH-Ephrin signaling (Sus scrofa)
EPH receptors autophosphorylate (Sus scrofa)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Sus scrofa)
SFKs phosphorylate VAV2,3 (Sus scrofa)
ADP [cytosol]
EPHB-mediated forward signaling (Sus scrofa)
EPHB phosphorylates TIAM1 (Sus scrofa)
ADP [cytosol]
PAK1 autophosphorylates (Sus scrofa)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Sus scrofa)
ADP [cytosol]
Ephrin signaling (Sus scrofa)
PAKs autophosphorylate (Sus scrofa)
ADP [cytosol]
PAKs phosphorylate MLC (Sus scrofa)
ADP [cytosol]
L1CAM interactions (Sus scrofa)
Recycling pathway of L1 (Sus scrofa)
Phosphorylation of L1 by ERK (Sus scrofa)
ADP [cytosol]
Signal transduction by L1 (Sus scrofa)
Interaction of PAK1 with Rac1-GTP (Sus scrofa)
ADP [cytosol]
MAP2K2 phosphorylates MAPK1 (Sus scrofa)
ADP [cytosol]
Netrin-1 signaling (Sus scrofa)
Phosphorylation and activation of Ezrin (Sus scrofa)
ADP [cytosol]
RET signaling (Sus scrofa)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Sus scrofa)
ADP [cytosol]
PKA phosphorylates RET:GDNF:GFRA dimer (Sus scrofa)
ADP [cytosol]
RET tyrosine phosphorylation (Sus scrofa)
ADP [cytosol]
Reelin signalling pathway (Sus scrofa)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Sus scrofa)
ADP [cytosol]
Semaphorin interactions (Sus scrofa)
CRMPs in Sema3A signaling (Sus scrofa)
Phosphorylation of CRMPs by Cdk5 (Sus scrofa)
ADP [cytosol]
Phosphorylation of CRMPs by GSK3beta (Sus scrofa)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Sus scrofa)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Sus scrofa)
Autophosphorylation of PAK (Sus scrofa)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Sus scrofa)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Sus scrofa)
ADP [cytosol]
Sema4D in semaphorin signaling (Sus scrofa)
Sema4D induced cell migration and growth-cone collapse (Sus scrofa)
SEMA4D interacts with Plexin-B1:ErbB2 (Sus scrofa)
ADP [cytosol]
Sema4D mediated inhibition of cell attachment and migration (Sus scrofa)
SEMA4D interacts with Plexin-B1:Met (Sus scrofa)
ADP [cytosol]
Drug ADME (Sus scrofa)
Aspirin ADME (Sus scrofa)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Sus scrofa)
ADP [cytosol]
Azathioprine ADME (Sus scrofa)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCC5 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Sus scrofa)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Sus scrofa)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Sus scrofa)
ADP [cytosol]
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Sus scrofa)
ADP [cytosol]
Ciprofloxacin ADME (Sus scrofa)
ABCG2 transports Cipro from hepatic cell to extracellular space (Sus scrofa)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Sus scrofa)
ADP [cytosol]
Paracetamol ADME (Sus scrofa)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Sus scrofa)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Sus scrofa)
ADP [cytosol]
Prednisone ADME (Sus scrofa)
ABCB1 transports PREDN,PREDL out of hepatic cells (Sus scrofa)
ADP [cytosol]
ABCB1 transports PREDN,PREDL out of kidney cells (Sus scrofa)
ADP [cytosol]
ABCB1 transports xenobiotics out of the cell (Sus scrofa)
ADP [cytosol]
Ribavirin ADME (Sus scrofa)
ADK phosphorylates RBV (Sus scrofa)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Sus scrofa)
ADP [cytosol]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
Regulation of TP53 Activity (Sus scrofa)
Regulation of TP53 Expression and Degradation (Sus scrofa)
Regulation of TP53 Degradation (Sus scrofa)
PDPK1 phosphorylates SGK1 (Sus scrofa)
ADP [cytosol]
SGK1 phosphorylates MDM2 (Sus scrofa)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Sus scrofa)
ADP [cytosol]
TP53 Regulates Metabolic Genes (Sus scrofa)
p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)
ADP [cytosol]
TP53 Regulates Transcription of Cell Cycle Genes (Sus scrofa)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Sus scrofa)
PLK2 phosphorylates CENPJ (Sus scrofa)
ADP [cytosol]
PLK2 phosphorylates NPM1 (Sus scrofa)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Sus scrofa)
ADP [cytosol]
Transcriptional regulation by RUNX3 (Sus scrofa)
Regulation of RUNX3 expression and activity (Sus scrofa)
SRC phosphorylates RUNX3 (Sus scrofa)
ADP [cytosol]
Hemostasis (Sus scrofa)
Cell surface interactions at the vascular wall (Sus scrofa)
PECAM1 interactions (Sus scrofa)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Sus scrofa)
ADP [cytosol]
Factors involved in megakaryocyte development and platelet production (Sus scrofa)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Sus scrofa)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Sus scrofa)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Sus scrofa)
ADP [cytosol]
Kinesins (Sus scrofa)
Kinesins move along microtubules consuming ATP (Sus scrofa)
ADP [cytosol]
Platelet activation, signaling and aggregation (Sus scrofa)
Effects of PIP2 hydrolysis (Sus scrofa)
DAG kinase produces phosphatidic acid from DAG (Sus scrofa)
ADP [cytosol]
GPVI-mediated activation cascade (Sus scrofa)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Sus scrofa)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
SYK autophosphorylates (Sus scrofa)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Sus scrofa)
ADP [cytosol]
Syk/Lck phosphorylate LAT (Sus scrofa)
ADP [cytosol]
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Sus scrofa)
ADP [cytosol]
Platelet Aggregation (Plug Formation) (Sus scrofa)
Integrin signaling (Sus scrofa)
Autophosphorylation of PTK2 at Y397 (Sus scrofa)
ADP [cytosol]
Autophosphorylation of SRC (Sus scrofa)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Sus scrofa)
ADP [cytosol]
SYK activation by SRC (Sus scrofa)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Sus scrofa)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Sus scrofa)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Sus scrofa)
Disinhibition of SNARE formation (Sus scrofa)
Phosphorylation of Platelet Sec-1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Sus scrofa)
ADP [cytosol]
Platelet degranulation (Sus scrofa)
ABCC4 accumulation of dense granule contents (Sus scrofa)
ADP [cytosol]
Signal amplification (Sus scrofa)
ADP signalling through P2Y purinoceptor 1 (Sus scrofa)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Sus scrofa)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Sus scrofa)
ADP [cytosol]
Platelet homeostasis (Sus scrofa)
Platelet sensitization by LDL (Sus scrofa)
FGR binds and phosphorylates LRP8 (Sus scrofa)
ADP [cytosol]
Fgr may phosphorylate p38 MAPK (Sus scrofa)
ADP [cytosol]
PECAM1 is phosphorylated (Sus scrofa)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Sus scrofa)
ADP [cytosol]
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen Presentation: Folding, assembly and peptide loading of class I MHC (Sus scrofa)
Transport of Antigen peptide in to ER (Sus scrofa)
ADP [cytosol]
Costimulation by the CD28 family (Sus scrofa)
CD28 co-stimulation (Sus scrofa)
CD28 dependent PI3K/Akt signaling (Sus scrofa)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Sus scrofa)
ADP [cytosol]
CD28 dependent Vav1 pathway (Sus scrofa)
Activation of Vav1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of CD28 (Sus scrofa)
ADP [cytosol]
CTLA4 inhibitory signaling (Sus scrofa)
Phosphorylation of CTLA-4 (Sus scrofa)
ADP [cytosol]
PD-1 signaling (Sus scrofa)
Phosphorylation of PD-1 (Sus scrofa)
ADP [cytosol]
MHC class II antigen presentation (Sus scrofa)
Transport of antigen loaded MHC II molecules to surface (Sus scrofa)
ADP [cytosol]
Rap1 signalling (Sus scrofa)
PKA/PKG phosphorylate Rap1GAP2 (Sus scrofa)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Sus scrofa)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Sus scrofa)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Sus scrofa)
ADP [cytosol]
SYK autophosphorylates at the activated BCR (Sus scrofa)
ADP [cytosol]
p-6Y-SYK phosphorylates BLNK (SLP65) (Sus scrofa)
ADP [cytosol]
CD22 mediated BCR regulation (Sus scrofa)
LYN phosphorylates CD22 (Sus scrofa)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Sus scrofa)
Activation of NF-kappaB in B cells (Sus scrofa)
Activated IKK phosphorylates I-kappaB (Sus scrofa)
ADP [cytosol]
TCR signaling (Sus scrofa)
Downstream TCR signaling (Sus scrofa)
Activation of IKK complex (Sus scrofa)
ADP [cytosol]
Activation of TAK1-TAB2 complex (Sus scrofa)
ADP [cytosol]
Change of PKC theta conformation (Sus scrofa)
ADP [cytosol]
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of Bcl10 (Sus scrofa)
ADP [cytosol]
Phosphorylation of CARMA1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of PKC theta (Sus scrofa)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Sus scrofa)
ADP [cytosol]
Generation of second messenger molecules (Sus scrofa)
Phosphorylation of PLC-gamma1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of SLP-76 (Sus scrofa)
ADP [cytosol]
Phosphorylation of TBSMs in LAT (Sus scrofa)
ADP [cytosol]
Phosphorylation of CD3 and TCR zeta chains (Sus scrofa)
Activation of Lck (Sus scrofa)
ADP [cytosol]
Inactivation of Lck by Csk (Sus scrofa)
ADP [cytosol]
Phosphorylation of ITAM motifs in CD3 complexes (Sus scrofa)
ADP [cytosol]
Translocation of ZAP-70 to Immunological synapse (Sus scrofa)
Activation of ZAP-70 (Sus scrofa)
ADP [cytosol]
Phosphorylation of ZAP-70 by Lck (Sus scrofa)
ADP [cytosol]
Cytokine Signaling in Immune system (Sus scrofa)
FLT3 Signaling (Sus scrofa)
Active FLT3 phosphorylates CDKN1B (Sus scrofa)
ADP [cytosol]
FLT3 phosphorylates GRB10 (Sus scrofa)
ADP [cytosol]
FLT3LG dimer:FLT3 dimer autophosphorylates (Sus scrofa)
ADP [cytosol]
Negative regulation of FLT3 (Sus scrofa)
FLT3 phosphorylates CBL (Sus scrofa)
ADP [cytosol]
Growth hormone receptor signaling (Sus scrofa)
JAK2 phosphorylation (Sus scrofa)
ADP [cytosol]
Lyn activates ERK (Sus scrofa)
ADP [cytosol]
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
PKR-mediated signaling (Sus scrofa)
p-PKR dimer phosphorylates CDK1 (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates MAPT (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates PPP2R5A (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates PTPN2 (Sus scrofa)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Sus scrofa)
ADP [cytosol]
Interferon alpha/beta signaling (Sus scrofa)
Activation of JAK kinases (Sus scrofa)
ADP [cytosol]
Formation of p-STAT1 homodimer (Sus scrofa)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Sus scrofa)
ADP [cytosol]
Phosphorylation of STAT2 (Sus scrofa)
ADP [cytosol]
Interferon gamma signaling (Sus scrofa)
IFNG signaling activates MAPKs (Sus scrofa)
JAK1-activated RAF1 phosphorylates MAPKs (Sus scrofa)
ADP [cytosol]
JAK1-mediated phosphorylation of RAF1 (Sus scrofa)
ADP [cytosol]
JAK2-activated MAPKs phosphorylate YBX1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of IFNGR1 by JAK kinases (Sus scrofa)
ADP [cytosol]
Phosphorylation of JAK2 (Sus scrofa)
ADP [cytosol]
Phosphorylation of STAT1 at Ser727 (Sus scrofa)
ADP [cytosol]
Phosphorylation of STAT1 by JAK kinases (Sus scrofa)
ADP [cytosol]
Transphosphorylation of JAK1 (Sus scrofa)
ADP [cytosol]
Prolactin receptor signaling (Sus scrofa)
JAK2 phosphorylation (Sus scrofa)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Sus scrofa)
ADP [cytosol]
Signaling by Interleukins (Sus scrofa)
Interleukin-1 family signaling (Sus scrofa)
Interleukin-1 signaling (Sus scrofa)
IKBA is phosphorylated by Phospho IKKB kinase (Sus scrofa)
ADP [cytosol]
IRAK4 is activated by autophosphorylation (Sus scrofa)
ADP [cytosol]
IRAK4 phosphorylates IRAK1 (Sus scrofa)
ADP [cytosol]
IRAK4-activated IRAK1 autophosphorylates (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Sus scrofa)
ADP [cytosol]
Interleukin-37 signaling (Sus scrofa)
STAT3 phosphorylation (Sus scrofa)
ADP [cytosol]
TBK1 phosphorylation (Sus scrofa)
ADP [cytosol]
Interleukin-38 signaling (Sus scrofa)
MAPK8 phosphorylation (Sus scrofa)
ADP [cytosol]
Interleukin-10 signaling (Sus scrofa)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Sus scrofa)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Sus scrofa)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Sus scrofa)
ADP [cytosol]
Interleukin-12 family signaling (Sus scrofa)
Interleukin-12 signaling (Sus scrofa)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Sus scrofa)
ADP [cytosol]
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Sus scrofa)
ADP [cytosol]
Interleukin-23 signaling (Sus scrofa)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Sus scrofa)
ADP [cytosol]
Interleukin-27 signaling (Sus scrofa)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Sus scrofa)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Sus scrofa)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Sus scrofa)
ADP [cytosol]
Interleukin-35 Signalling (Sus scrofa)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Sus scrofa)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Sus scrofa)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Sus scrofa)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Sus scrofa)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Sus scrofa)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Sus scrofa)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Sus scrofa)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Sus scrofa)
ADP [cytosol]
Interleukin-17 signaling (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
Interleukin-2 family signaling (Sus scrofa)
Interleukin receptor SHC signaling (Sus scrofa)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
ADP [cytosol]
Interleukin-15 signaling (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Sus scrofa)
ADP [cytosol]
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Sus scrofa)
ADP [cytosol]
Interleukin-2 signaling (Sus scrofa)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Sus scrofa)
ADP [cytosol]
Recruited STAT5 is phosphorylated (Sus scrofa)
ADP [cytosol]
SHC1 bound to IL2 receptor is phosphorylated (Sus scrofa)
ADP [cytosol]
SYK is a substrate for JAK1 (Sus scrofa)
ADP [cytosol]
Within the IL-2R complex JAK3 phosphorylates JAK1 (Sus scrofa)
ADP [cytosol]
Interleukin-21 signaling (Sus scrofa)
IL21 receptor JAK phosphorylation (Sus scrofa)
ADP [cytosol]
IL21 receptor STAT phosphorylation (Sus scrofa)
ADP [cytosol]
Interleukin-9 signaling (Sus scrofa)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Sus scrofa)
ADP [cytosol]
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Sus scrofa)
ADP [cytosol]
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Sus scrofa)
ADP [cytosol]
Interleukin-20 family signaling (Sus scrofa)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Sus scrofa)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Sus scrofa)
ADP [cytosol]
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)
ADP [cytosol]
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Sus scrofa)
ADP [cytosol]
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Sus scrofa)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Sus scrofa)
ADP [cytosol]
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)
ADP [cytosol]
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Sus scrofa)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Sus scrofa)
ADP [cytosol]
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Sus scrofa)
ADP [cytosol]
Interleukin-3, Interleukin-5 and GM-CSF signaling (Sus scrofa)
Activation of STAT5a/b by JAK2 (Sus scrofa)
ADP [cytosol]
Interleukin receptor SHC signaling (Sus scrofa)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
ADP [cytosol]
JAK2 is phosphorylated, activated (Sus scrofa)
ADP [cytosol]
Tyrosine kinases phosphorylate the receptor (Sus scrofa)
ADP [cytosol]
Interleukin-4 and Interleukin-13 signaling (Sus scrofa)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Sus scrofa)
ADP [cytosol]
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Sus scrofa)
ADP [cytosol]
JAK1 phosphorylates STAT3,STAT6 (Sus scrofa)
ADP [cytosol]
STAT1,STAT3,STAT6 phosphorylation (Sus scrofa)
ADP [cytosol]
Interleukin-6 family signaling (Sus scrofa)
Interleukin-6 signaling (Sus scrofa)
IL6ST is tyrosine phosphorylated (Sus scrofa)
ADP [cytosol]
JAK activation (Sus scrofa)
ADP [cytosol]
PTPN11 is phosphorylated (Sus scrofa)
ADP [cytosol]
Serine phosphorylation of STATs (Sus scrofa)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Sus scrofa)
ADP [cytosol]
Interleukin-7 signaling (Sus scrofa)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Sus scrofa)
ADP [cytosol]
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Sus scrofa)
ADP [cytosol]
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Sus scrofa)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Sus scrofa)
NIK-->noncanonical NF-kB signaling (Sus scrofa)
Active NIK phosphorylates IKKA dimer (Sus scrofa)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Sus scrofa)
ADP [cytosol]
NIK autophosphorylates on T559 (Sus scrofa)
ADP [cytosol]
Innate Immune System (Sus scrofa)
Alpha-protein kinase 1 signaling pathway (Sus scrofa)
ALPK1 phosphorylates TIFA (Sus scrofa)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Sus scrofa)
ADP [cytosol]
Antimicrobial peptides (Sus scrofa)
Ion influx/efflux at host-pathogen interface (Sus scrofa)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Sus scrofa)
ADP [cytosol]
C-type lectin receptors (CLRs) (Sus scrofa)
CLEC7A (Dectin-1) signaling (Sus scrofa)
Dectin-1 mediated noncanonical NF-kB signaling (Sus scrofa)
Active NIK phosphorylates IKKA dimer (Sus scrofa)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Sus scrofa)
ADP [cytosol]
K63polyUb-TAK1 autophosphorylates (Sus scrofa)
ADP [cytosol]
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Sus scrofa)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Sus scrofa)
ADP [cytosol]
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Sus scrofa)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Sus scrofa)
ADP [cytosol]
Dectin-2 family (Sus scrofa)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Sus scrofa)
ADP [cytosol]
SYK autophosphorylates (Sus scrofa)
ADP [cytosol]
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Sus scrofa)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Sus scrofa)
STING mediated induction of host immune responses (Sus scrofa)
IRF3-mediated induction of type I IFN (Sus scrofa)
IRF3 is phosphorylated by TBK1 (Sus scrofa)
ADP [cytosol]
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Sus scrofa)
ADP [cytosol]
STAT6-mediated induction of chemokines (Sus scrofa)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Sus scrofa)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Sus scrofa)
ADP [cytosol]
ZBP1(DAI) mediated induction of type I IFNs (Sus scrofa)
RIP-mediated NFkB activation via ZBP1 (Sus scrofa)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
DAP12 interactions (Sus scrofa)
DAP12 signaling (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phosphorylation and activation of VAV2/VAV3 by SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of BTK by p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of SYK (Sus scrofa)
ADP [cytosol]
DDX58/IFIH1-mediated induction of interferon-alpha/beta (Sus scrofa)
TRAF6 mediated NF-kB activation (Sus scrofa)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
Autophosphorylation of LYN kinase (Sus scrofa)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Sus scrofa)
Autophosphorylation of BTK/ITK (Sus scrofa)
ADP [cytosol]
Phosphorylation of TEC kinases by p-SYK (Sus scrofa)
ADP [cytosol]
FCERI mediated MAPK activation (Sus scrofa)
Autophosphorylation of PAK (Sus scrofa)
ADP [cytosol]
Phosphorylation and activation of VAV (Sus scrofa)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of SHC by SYK kinase (Sus scrofa)
ADP [cytosol]
Phosphorylation of SLP-76 by p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
FCERI mediated NF-kB activation (Sus scrofa)
Activation of TAK1 complex bound to pUb-TRAF6 (Sus scrofa)
ADP [cytosol]
Autophosphorylation of PKC-theta (Sus scrofa)
ADP [cytosol]
Phosphorylation of CARMA1 by PKC-theta (Sus scrofa)
ADP [cytosol]
Phosphorylation of IKK-beta by TAK1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of PKC-theta (Sus scrofa)
ADP [cytosol]
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Sus scrofa)
ADP [cytosol]
Phosphorylation of LAT by p-SYK (Sus scrofa)
ADP [cytosol]
Phosphorylation of beta and gamma subunits by LYN (Sus scrofa)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Sus scrofa)
Phosphorylation of NTAL by p-SYK/Lyn (Sus scrofa)
ADP [cytosol]
Phosphorylation of PIP2 to PIP3 by PI3K (Sus scrofa)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Sus scrofa)
FCGR activation (Sus scrofa)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Sus scrofa)
ADP [cytosol]
Regulation of actin dynamics for phagocytic cup formation (Sus scrofa)
ABL phosphorylates WAVEs (Sus scrofa)
ADP [cytosol]
Autophosphorylation of PAK1 (Sus scrofa)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Sus scrofa)
Mother filament:ARP2/3:actin:ADP [cytosol] (Sus scrofa)
Actin:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Detachment of WASP/WAVE (Sus scrofa)
Mother filament:ARP2/3:actin:ADP [cytosol] (Sus scrofa)
Actin:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Extension of pseudopodia by myosin-X in a PI3K dependent manner (Sus scrofa)
Actin filament bound Myosin-X [plasma membrane] (Sus scrofa)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of VAV (Sus scrofa)
ADP [cytosol]
Role of myosins in phagosome formation (Sus scrofa)
Myosin-Actin filaments [cytosol] (Sus scrofa)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Sus scrofa)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Sus scrofa)
ADP [cytosol]
Role of phospholipids in phagocytosis (Sus scrofa)
DAG stimulates protein kinase C-delta (Sus scrofa)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phosphorylation and activation of PLCG (Sus scrofa)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Sus scrofa)
NOD1/2 Signaling Pathway (Sus scrofa)
Activation of p38 MAPK (Sus scrofa)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Sus scrofa)
ADP [cytosol]
Toll-like Receptor Cascades (Sus scrofa)
Toll Like Receptor 10 (TLR10) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
IRAK1 recruits IKK complex (Sus scrofa)
IRAK1 phosphorylates Pellino (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Sus scrofa)
Toll Like Receptor TLR1:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK1 recruits IKK complex (Sus scrofa)
IRAK1 phosphorylates Pellino (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Sus scrofa)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK1 recruits IKK complex (Sus scrofa)
IRAK1 phosphorylates Pellino (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Sus scrofa)
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Sus scrofa)
MyD88-independent TLR4 cascade (Sus scrofa)
TRIF (TICAM1)-mediated TLR4 signaling (Sus scrofa)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Sus scrofa)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Sus scrofa)
ADP [cytosol]
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
ADP [cytosol]
TBK1 is phosphorylated within the activated TLR4 complex (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Sus scrofa)
Activation of TAK1 complex bound to activated TLR4 complex (Sus scrofa)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Sus scrofa)
IRAK1 recruits IKK complex (Sus scrofa)
IRAK1 phosphorylates Pellino (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Sus scrofa)
MyD88 cascade initiated on plasma membrane (Sus scrofa)
IRAK1 recruits IKK complex (Sus scrofa)
IRAK1 phosphorylates Pellino (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Sus scrofa)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Sus scrofa)
MyD88 dependent cascade initiated on endosome (Sus scrofa)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Sus scrofa)
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation (Sus scrofa)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Sus scrofa)
ADP [cytosol]
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Sus scrofa)
ADP [cytosol]
MAP kinase activation (Sus scrofa)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
ADP [cytosol]
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
ADP [cytosol]
MAP3K8 is phosphorylated (Sus scrofa)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
ADP [cytosol]
TAK1-dependent IKK and NF-kappa-B activation (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
ADP [cytosol]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Pyruvate metabolism (Sus scrofa)
PKM dephosphorylates PEP to PYR (Sus scrofa)
ADP [cytosol]
Regulation of pyruvate metabolism (Sus scrofa)
NEK1 phosphorylates ME1 (Sus scrofa)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Sus scrofa)
Mitochondrial Uncoupling (Sus scrofa)
The proton buffering model (Sus scrofa)
Protons are translocated from the intermembrane space to the matrix (Sus scrofa)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
Transport and synthesis of PAPS (Sus scrofa)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Sus scrofa)
ADP [cytosol]
Glutathione conjugation (Sus scrofa)
Glutathione synthesis and recycling (Sus scrofa)
GCL ligates L-Glu to L-Cys (Sus scrofa)
ADP [cytosol]
GSS:Mg2+ dimer synthesizes GSH (Sus scrofa)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Sus scrofa)
ADP [cytosol]
Inositol phosphate metabolism (Sus scrofa)
Synthesis of IP3 and IP4 in the cytosol (Sus scrofa)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Sus scrofa)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
ADP [cytosol]
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Sus scrofa)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Sus scrofa)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Sus scrofa)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Sus scrofa)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Sus scrofa)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Sus scrofa)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Sus scrofa)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Sus scrofa)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Sus scrofa)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Sus scrofa)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Sus scrofa)
ADP [cytosol]
Integration of energy metabolism (Sus scrofa)
Regulation of insulin secretion (Sus scrofa)
Acetylcholine regulates insulin secretion (Sus scrofa)
Protein kinase C, alpha type phosphorylates MARCKS (Sus scrofa)
ADP [cytosol]
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Sus scrofa)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Creatine metabolism (Sus scrofa)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Sus scrofa)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Sus scrofa)
ADP [cytosol]
Glutamate and glutamine metabolism (Sus scrofa)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Sus scrofa)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Sus scrofa)
ADP [cytosol]
Histidine catabolism (Sus scrofa)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Sus scrofa)
ADP [cytosol]
Metabolism of carbohydrates (Sus scrofa)
Formation of xylulose-5-phosphate (Sus scrofa)
XYLB phosphorylates D-xylulose (Sus scrofa)
ADP [cytosol]
Fructose metabolism (Sus scrofa)
Fructose catabolism (Sus scrofa)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Sus scrofa)
ADP [cytosol]
GLYCTK phosphorylates DGA to 3PDGA (Sus scrofa)
ADP [cytosol]
KHK dimer phosphorylates Fru to Fru 1-P (Sus scrofa)
ADP [cytosol]
Galactose catabolism (Sus scrofa)
GALK1 phosphorylates Gal to Gal1P (Sus scrofa)
ADP [cytosol]
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Sus scrofa)
ADP [cytosol]
Glycolysis (Sus scrofa)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Sus scrofa)
ADP [cytosol]
ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)
ADP [cytosol]
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Sus scrofa)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Sus scrofa)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Sus scrofa)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Sus scrofa)
ADP [cytosol]
Glycogen metabolism (Sus scrofa)
Glycogen breakdown (glycogenolysis) (Sus scrofa)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Sus scrofa)
ADP [cytosol]
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Sus scrofa)
ADP [cytosol]
Glycosaminoglycan metabolism (Sus scrofa)
Transport and synthesis of PAPS (Sus scrofa)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Sus scrofa)
ADP [cytosol]
Pentose phosphate pathway (Sus scrofa)
RBKS phosphorylates ribose to R5P (Sus scrofa)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Sus scrofa)
ADP [cytosol]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Arachidonic acid metabolism (Sus scrofa)
Synthesis of Leukotrienes (LT) and Eoxins (EX) (Sus scrofa)
ALOX5 is phosphorylated by MAPKAP2 (Sus scrofa)
ADP [cytosol]
Carnitine metabolism (Sus scrofa)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
ADP [cytosol]
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Sus scrofa)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Sus scrofa)
ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Sus scrofa)
ADP [cytosol]
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Recycling of bile acids and salts (Sus scrofa)
ABCB11 transports bile salts from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCC3 transports bile salts from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
Synthesis of bile acids and bile salts (Sus scrofa)
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
ABCB11 transports bile salts from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
Cholesterol biosynthesis (Sus scrofa)
MVD decarboxylates MVA5PP to IPPP (Sus scrofa)
ADP [cytosol]
Mevalonate is phosphorylated to mevalonate-5-phosphate (Sus scrofa)
ADP [cytosol]
Mevalonate-5-phosphate is further phosphorylated. (Sus scrofa)
ADP [cytosol]
Phospholipid metabolism (Sus scrofa)
Glycerophospholipid biosynthesis (Sus scrofa)
Synthesis of PC (Sus scrofa)
Casein kinase II phosphorylates STARD10 (Sus scrofa)
ADP [cytosol]
Cho is phosphorylated to PCho by CHK dimer (Sus scrofa)
ADP [cytosol]
Synthesis of PE (Sus scrofa)
ETA is phosphorylated to PETA by CHK/ETNK (Sus scrofa)
ADP [cytosol]
PI Metabolism (Sus scrofa)
Synthesis of PIPs at the ER membrane (Sus scrofa)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Sus scrofa)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Sus scrofa)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Sus scrofa)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Sus scrofa)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Sus scrofa)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Sus scrofa)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Sus scrofa)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Sus scrofa)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Sus scrofa)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Sus scrofa)
BMX phosphorylates RUFY1 (Sus scrofa)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Sus scrofa)
ADP [cytosol]
Sphingolipid metabolism (Sus scrofa)
Glycosphingolipid metabolism (Sus scrofa)
Glycosphingolipid biosynthesis (Sus scrofa)
CERK phosphorylates CERA to form C1P (Sus scrofa)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Sus scrofa)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Sus scrofa)
ADP [cytosol]
SPHK1 phosphorylates sphingoid (Sus scrofa)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Sus scrofa)
ADP [cytosol]
Triglyceride metabolism (Sus scrofa)
Triglyceride biosynthesis (Sus scrofa)
Conversion of Glycerol to Glycerol-3-phosphate (Sus scrofa)
ADP [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Sus scrofa)
eNOS activation (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
ADP [cytosol]
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Sus scrofa)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Sus scrofa)
(d)ADP [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Sus scrofa)
ADP [cytosol]
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Sus scrofa)
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Sus scrofa)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Sus scrofa)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Sus scrofa)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Sus scrofa)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Sus scrofa)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Sus scrofa)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Sus scrofa)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Sus scrofa)
ADP [cytosol]
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Sus scrofa)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Sus scrofa)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Sus scrofa)
ADP [cytosol]
Nucleotide biosynthesis (Sus scrofa)
Purine ribonucleoside monophosphate biosynthesis (Sus scrofa)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Sus scrofa)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Sus scrofa)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Sus scrofa)
ADP [cytosol]
Pyrimidine biosynthesis (Sus scrofa)
CAD hexamer transforms L-Gln to CAP (Sus scrofa)
ADP [cytosol]
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Sus scrofa)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Sus scrofa)
ADP [cytosol]
Pyrimidine catabolism (Sus scrofa)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Sus scrofa)
ADP [cytosol]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Sus scrofa)
ADP [cytosol]
Pyrimidine salvage (Sus scrofa)
UCKL1 phosphorylates urindine, cytidine (Sus scrofa)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Sus scrofa)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Sus scrofa)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Sus scrofa)
ADP [cytosol]
Metabolism of porphyrins (Sus scrofa)
Heme biosynthesis (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
Heme degradation (Sus scrofa)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Sus scrofa)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Sus scrofa)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Sus scrofa)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Transport of RCbl within the body (Sus scrofa)
ABCC1 transports cytosolic RCbl to extracellular region (Sus scrofa)
ADP [cytosol]
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Sus scrofa)
ADP [cytosol]
Uptake of dietary cobalamins into enterocytes (Sus scrofa)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Sus scrofa)
ADP [cytosol]
Metabolism of folate and pterines (Sus scrofa)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Sus scrofa)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Sus scrofa)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Sus scrofa)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Sus scrofa)
ADP [cytosol]
Nicotinate metabolism (Sus scrofa)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Sus scrofa)
ADP [cytosol]
NMRK1 phosphorylates NAR to yield NAMN (Sus scrofa)
ADP [cytosol]
NMRK1 phosphorylates NR to yield NMN (Sus scrofa)
ADP [cytosol]
NMRK2 phosphorylates NAR to yield NAMN (Sus scrofa)
ADP [cytosol]
NMRK2 phosphorylates NR to yield NMN (Sus scrofa)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Sus scrofa)
RFK:Mg2+ phosphorylates RIB (Sus scrofa)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Sus scrofa)
Coenzyme A biosynthesis (Sus scrofa)
COASY phosphorylates DP-CoA (Sus scrofa)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Sus scrofa)
ADP [cytosol]
PANK1/3 phosphorylate PanK (Sus scrofa)
ADP [cytosol]
PANK2 phosphorylates PanK (Sus scrofa)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Sus scrofa)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Sus scrofa)
2xPDKX:2xZn2+ phosphorylates PDX (Sus scrofa)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Sus scrofa)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Sus scrofa)
ADP [cytosol]
Metabolism of RNA (Sus scrofa)
Nonsense-Mediated Decay (NMD) (Sus scrofa)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Sus scrofa)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Sus scrofa)
ADP [cytosol]
Regulation of mRNA stability by proteins that bind AU-rich elements (Sus scrofa)
Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA (Sus scrofa)
MK2 phosphorylates BRF1 (Sus scrofa)
ADP [cytosol]
Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA (Sus scrofa)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Sus scrofa)
ADP [cytosol]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
Synthesis of substrates in N-glycan biosythesis (Sus scrofa)
GDP-fucose biosynthesis (Sus scrofa)
FUK phosphorylates beta-Fuc to Fuc1P (Sus scrofa)
ADP [cytosol]
Sialic acid metabolism (Sus scrofa)
GNE phosphorylates ManNAc to ManNAc-6-P (Sus scrofa)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Sus scrofa)
MVD decarboxylates MVA5PP to IPPP (Sus scrofa)
ADP [cytosol]
Synthesis of UDP-N-acetyl-glucosamine (Sus scrofa)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Sus scrofa)
ADP [cytosol]
Transport to the Golgi and subsequent modification (Sus scrofa)
ER to Golgi Anterograde Transport (Sus scrofa)
COPI-mediated anterograde transport (Sus scrofa)
GBF1 stimulates ARF nucleotide exchange (Sus scrofa)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Sus scrofa)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Sus scrofa)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Sus scrofa)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Sus scrofa)
FN3K phosphorylates ketosamines (Sus scrofa)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Sus scrofa)
ADP [cytosol]
Protein folding (Sus scrofa)
Chaperonin-mediated protein folding (Sus scrofa)
Association of TriC/CCT with target proteins during biosynthesis (Sus scrofa)
Association of CCT/TriC with sphingosine kinase 1 (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
CCT/TRiC:ADP:Sphingosine kinase 1 [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Sus scrofa)
ATP binds G-protein beta associated TRiC/CCT (Sus scrofa)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Sus scrofa)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
CK2 phosphorylates PDCL (Sus scrofa)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Sus scrofa)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Sus scrofa)
GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Sus scrofa)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
RGS proteins bind GNB5 and CCT/TRiC (Sus scrofa)
GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Sus scrofa)
GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Release of GNB5:RGS dimers from CCT/TRiC (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
RGS7,RGS9,(RGS6,RGS11):GNB5:CCT/TRiC:ADP [plasma membrane] (Sus scrofa)
GNB5:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Surfactant metabolism (Sus scrofa)
ABCA3 transports PC, PG from ER membrane to lamellar body (Sus scrofa)
ADP [cytosol]
Translation (Sus scrofa)
Eukaryotic Translation Initiation (Sus scrofa)
Cap-dependent Translation Initiation (Sus scrofa)
Ribosomal scanning and start codon recognition (Sus scrofa)
Ribosomal scanning (Sus scrofa)
ADP [cytosol]
Muscle contraction (Sus scrofa)
Cardiac conduction (Sus scrofa)
Ion homeostasis (Sus scrofa)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Sus scrofa)
ADP [cytosol]
DMPK phosphorylates PLN (Sus scrofa)
ADP [cytosol]
PRKACA phosphorylates PLN (Sus scrofa)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Sus scrofa)
ADP [cytosol]
Smooth Muscle Contraction (Sus scrofa)
ATP Hydrolysis By Myosin (Sus scrofa)
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Sus scrofa)
ADP [cytosol]
Phosphorylation of Smooth Muscle Myosin Light Chains (Sus scrofa)
ADP [cytosol]
Release Of ADP From Myosin (Sus scrofa)
ADP [cytosol]
ADP:Calcium Bound Myosin Actin Complex [plasma membrane] (Sus scrofa)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Sus scrofa)
ADP [cytosol]
Striated Muscle Contraction (Sus scrofa)
ATP Hydrolysis By Myosin (Sus scrofa)
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
ADP Bound Myosin Complex [cytosol] (Sus scrofa)
ADP [cytosol]
Release Of ADP From Myosin (Sus scrofa)
ADP [cytosol]
ADP:Calcium Bound Sarcomere Protein Complex [cytosol] (Sus scrofa)
ADP Bound Myosin Complex [cytosol] (Sus scrofa)
ADP [cytosol]
Neuronal System (Sus scrofa)
Transmission across Chemical Synapses (Sus scrofa)
Neurotransmitter receptors and postsynaptic signal transmission (Sus scrofa)
Activation of NMDA receptors and postsynaptic events (Sus scrofa)
Post NMDA receptor activation events (Sus scrofa)
Activation of RAC1 downstream of NMDARs (Sus scrofa)
CaMKK autophosphorylates in the cytosol (Sus scrofa)
ADP [cytosol]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Sus scrofa)
Trafficking of AMPA receptors (Sus scrofa)
Trafficking of GluR1-containing AMPA receptors (Sus scrofa)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors (Sus scrofa)
Endocytosis of Ca impermeable AMPA receptors (Sus scrofa)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Sus scrofa)
ADP [cytosol]
Trafficking of GluR2-containing AMPA receptors to synapse (Sus scrofa)
ADP [cytosol]
Neurotransmitter uptake and metabolism In glial cells (Sus scrofa)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Sus scrofa)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Sus scrofa)
ADP [cytosol]
Programmed Cell Death (Sus scrofa)
Apoptosis (Sus scrofa)
Caspase activation via extrinsic apoptotic signalling pathway (Sus scrofa)
Caspase activation via Dependence Receptors in the absence of ligand (Sus scrofa)
Activation of caspase-3 (Sus scrofa)
ADP [cytosol]
Intrinsic Pathway for Apoptosis (Sus scrofa)
Activation of BH3-only proteins (Sus scrofa)
Activation of BIM and translocation to mitochondria (Sus scrofa)
Phosphorylation of BIM by JNK (Sus scrofa)
ADP [cytosol]
Activation of BMF and translocation to mitochondria (Sus scrofa)
Phosphorylation of DLC2 by MAPK8 (Sus scrofa)
ADP [cytosol]
Apoptotic factor-mediated response (Sus scrofa)
Cytochrome c-mediated apoptotic response (Sus scrofa)
Activation of caspases through apoptosome-mediated cleavage (Sus scrofa)
Cleavage of Procaspase-3 by the apoptosome (Sus scrofa)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Sus scrofa)
ADP [cytosol]
Formation of apoptosome (Sus scrofa)
CYCS binds to APAF1 (Sus scrofa)
ADP [cytosol]
APAF1:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Sus scrofa)
ADP [cytosol]
Regulation of the apoptosome activity (Sus scrofa)
APAF1 binds AVEN (Sus scrofa)
APAF1:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
APAF1:AVEN [cytosol] (Sus scrofa)
APAF1:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Sus scrofa)
ADP [cytosol]
Regulated Necrosis (Sus scrofa)
RIPK1-mediated regulated necrosis (Sus scrofa)
RIPK1 is phosphorylated (Sus scrofa)
ADP [cytosol]
RIPK3 is phosphorylated (Sus scrofa)
ADP [cytosol]
RIPK3 phosphorylates MLKL (Sus scrofa)
ADP [cytosol]
Protein localization (Sus scrofa)
Peroxisomal protein import (Sus scrofa)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Sus scrofa)
ADP [cytosol]
Sensory Perception (Sus scrofa)
Visual phototransduction (Sus scrofa)
The canonical retinoid cycle in rods (twilight vision) (Sus scrofa)
ABCA4 mediates atRAL transport (Sus scrofa)
ADP [cytosol]
The phototransduction cascade (Sus scrofa)
Inactivation, recovery and regulation of the phototransduction cascade (Sus scrofa)
GRK1,4,7 phosphorylate MII to p-MII (Sus scrofa)
ADP [cytosol]
Signal Transduction (Sus scrofa)
Death Receptor Signaling (Sus scrofa)
TNF signaling (Sus scrofa)
Regulation of TNFR1 signaling (Sus scrofa)
CHUK, IKBKB phosphorylate CYLD at S418 (Sus scrofa)
ADP [cytosol]
CHUK, IKBKB phosphorylate RIPK1 at S25 (Sus scrofa)
ADP [cytosol]
MAPKAPK2 phosphorylates RIPK1 at S320 (Sus scrofa)
ADP [cytosol]
TBK1, IKBKE phosphorylate RIPK1 at T189 (Sus scrofa)
ADP [cytosol]
ULK1 phosphorylates RIPK1 at S357 (Sus scrofa)
ADP [cytosol]
p75 NTR receptor-mediated signalling (Sus scrofa)
Cell death signalling via NRAGE, NRIF and NADE (Sus scrofa)
NRAGE signals death through JNK (Sus scrofa)
GTP-bound RAC contributes to JNK activation (Sus scrofa)
ADP [cytosol]
JNK phosphorylates BIM, BAD and other targets (Sus scrofa)
ADP [cytosol]
p75NTR signals via NF-kB (Sus scrofa)
NF-kB is activated and signals survival (Sus scrofa)
IKKbeta is activated (Sus scrofa)
ADP [cytosol]
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Sus scrofa)
ADP [cytosol]
Integrin signaling (Sus scrofa)
Autophosphorylation of PTK2 at Y397 (Sus scrofa)
ADP [cytosol]
Autophosphorylation of SRC (Sus scrofa)
ADP [cytosol]
Phosphorylation of pPTK2 by SRC (Sus scrofa)
ADP [cytosol]
SYK activation by SRC (Sus scrofa)
ADP [cytosol]
p130Cas linkage to MAPK signaling for integrins (Sus scrofa)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Sus scrofa)
ADP [cytosol]
Intracellular signaling by second messengers (Sus scrofa)
DAG and IP3 signaling (Sus scrofa)
CaM pathway (Sus scrofa)
Calmodulin induced events (Sus scrofa)
PKC phosphorylates GRK2 (Sus scrofa)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Sus scrofa)
ADP [cytosol]
PIP3 activates AKT signaling (Sus scrofa)
Negative regulation of the PI3K/AKT network (Sus scrofa)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Sus scrofa)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Sus scrofa)
ADP [cytosol]
MAPKs phosphorylate PP2A (Sus scrofa)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Sus scrofa)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Sus scrofa)
ADP [cytosol]
PDPK1 phosphorylates SGK1 (Sus scrofa)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
PTEN Regulation (Sus scrofa)
Regulation of PTEN gene transcription (Sus scrofa)
mTORC1 phosphorylates MAF1 (Sus scrofa)
ADP [cytosol]
Regulation of PTEN stability and activity (Sus scrofa)
Casein kinase II phosphorylates PTEN (Sus scrofa)
ADP [cytosol]
FRK phosphorylates PTEN (Sus scrofa)
ADP [cytosol]
TORC2 complex phosphorylates SGK1 (Sus scrofa)
ADP [cytosol]
MAPK family signaling cascades (Sus scrofa)
MAPK1/MAPK3 signaling (Sus scrofa)
RAF-independent MAPK1/3 activation (Sus scrofa)
MAPK1 (ERK2) activation (Sus scrofa)
MAP2K2 phosphorylates MAPK1 (Sus scrofa)
ADP [cytosol]
RAF/MAP kinase cascade (Sus scrofa)
MAP2K and MAPK activation (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
ADP [cytosol]
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs (Sus scrofa)
ADP [cytosol]
RAF phosphorylates MAP2K dimer (Sus scrofa)
ADP [cytosol]
Negative regulation of MAPK pathway (Sus scrofa)
MAPK12 phosphorylates PTPN3 (Sus scrofa)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Sus scrofa)
Activated MAPKs phosphorylate BRAF (Sus scrofa)
ADP [cytosol]
RAF activation (Sus scrofa)
MARK3 phosphorylates KSR1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of RAF (Sus scrofa)
ADP [cytosol]
RAS processing (Sus scrofa)
KRAS4B is phosphorylated on serine 181 (Sus scrofa)
ADP [cytosol]
MAPK6/MAPK4 signaling (Sus scrofa)
Autophosphorylation of PAK1,2,3 (Sus scrofa)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Sus scrofa)
ADP [cytosol]
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Sus scrofa)
ADP [cytosol]
p-S MAPKAPK5 phosphorylates HSPB1 (Sus scrofa)
ADP [cytosol]
p-T182 MAPKAPK5 phosphorylates FOXO3 (Sus scrofa)
ADP [cytosol]
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Sus scrofa)
ADP [cytosol]
MTOR signalling (Sus scrofa)
Energy dependent regulation of mTOR by LKB1-AMPK (Sus scrofa)
AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)
ADP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Sus scrofa)
ADP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)
ADP [cytosol]
Inhibition of TSC complex formation by PKB (Sus scrofa)
Phosphorylation of TSC2 by PKB (Sus scrofa)
ADP [cytosol]
Phosphorylation of complexed TSC2 by PKB (Sus scrofa)
ADP [cytosol]
mTORC1 phosphorylates AKT1S1 (Sus scrofa)
ADP [cytosol]
mTORC1-mediated signalling (Sus scrofa)
Phosphorylation and activation of eIF4B by activated S6K1 (Sus scrofa)
ADP [cytosol]
Phosphorylation and activation of eIF4G by activated S6K1 (Sus scrofa)
ADP [cytosol]
Phosphorylation and inactivation of eEF2K by activated S6K1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of 4E-BP1 by activated mTORC1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Sus scrofa)
ADP [cytosol]
mTORC1 phosphorylation of RPS6KB1 (S6K) (Sus scrofa)
ADP [cytosol]
Signaling by Erythropoietin (Sus scrofa)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Sus scrofa)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Sus scrofa)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Sus scrofa)
ADP [cytosol]
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Sus scrofa)
ADP [cytosol]
Opioid Signalling (Sus scrofa)
DARPP-32 events (Sus scrofa)
PKA phosphorylates DARPP-32 on Thr34 (Sus scrofa)
ADP [cytosol]
PKA phosphorylates PDE4B (Sus scrofa)
ADP [cytosol]
G-protein mediated events (Sus scrofa)
PLC beta mediated events (Sus scrofa)
Ca-dependent events (Sus scrofa)
CaM pathway (Sus scrofa)
Calmodulin induced events (Sus scrofa)
PKC phosphorylates GRK2 (Sus scrofa)
ADP [cytosol]
phospho-PLA2 pathway (Sus scrofa)
Phosphorylation of cPLA2 by ERK-2 (Sus scrofa)
ADP [cytosol]
G alpha (q) signalling events (Sus scrofa)
Effects of PIP2 hydrolysis (Sus scrofa)
DAG kinase produces phosphatidic acid from DAG (Sus scrofa)
ADP [cytosol]
G alpha (s) signalling events (Sus scrofa)
ADRB2 in ADRB2:GRK complex is phosphorylated (Sus scrofa)
ADP [cytosol]
G-protein beta:gamma signalling (Sus scrofa)
G beta:gamma signalling through PI3Kgamma (Sus scrofa)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Signaling by Hedgehog (Sus scrofa)
Hedgehog 'off' state (Sus scrofa)
GLI3 is processed to GLI3R by the proteasome (Sus scrofa)
CK1 phosphorylates p-GLI3 (Sus scrofa)
ADP [cytosol]
GSK3 phosphorylates p-GLI3 (Sus scrofa)
ADP [cytosol]
PKA phosphorylates GLI3 (Sus scrofa)
ADP [cytosol]
Hedgehog ligand biogenesis (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Sus scrofa)
ADP [cytosol]
Signaling by Hippo (Sus scrofa)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Sus scrofa)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Sus scrofa)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Sus scrofa)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Sus scrofa)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Sus scrofa)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Sus scrofa)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Sus scrofa)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Sus scrofa)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Sus scrofa)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS2 (Sus scrofa)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of YAP by LATS2 (Sus scrofa)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Sus scrofa)
Signaling by PTK6 (Sus scrofa)
ERBB2 Activates PTK6 Signaling (Sus scrofa)
ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)
ADP [cytosol]
PTK6 Activates STAT3 (Sus scrofa)
PTK6 phosphorylates STAP2 (Sus scrofa)
ADP [cytosol]
PTK6 phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
PTK6 Down-Regulation (Sus scrofa)
SRMS phosphorylates PTK6 (Sus scrofa)
ADP [cytosol]
PTK6 Regulates Cell Cycle (Sus scrofa)
PTK6 phosphorylates CDKN1B (Sus scrofa)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Sus scrofa)
PTK6 phosphorylates ARHGAP35 (Sus scrofa)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Sus scrofa)
ADP [cytosol]
PTK6 phosphorylates PXN (Sus scrofa)
ADP [cytosol]
PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1 (Sus scrofa)
PTK6 phosphorylates ARAP1 (Sus scrofa)
ADP [cytosol]
PTK6 phosphorylates CBL (Sus scrofa)
ADP [cytosol]
PTK6 phosphorylates DOK1 (Sus scrofa)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Sus scrofa)
EGFR phosphorylates GPNMB (Sus scrofa)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Sus scrofa)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Sus scrofa)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Sus scrofa)
ADP [cytosol]
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
ESR-associated SRC autophosphorylates (Sus scrofa)
ADP [cytosol]
Estrogen-stimulated signaling through PRKCZ (Sus scrofa)
PRKCZ autophosphorylates downstream of estrogen stimulation (Sus scrofa)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by ALK (Sus scrofa)
ALK autophosphorylation (Sus scrofa)
ADP [cytosol]
Active ALK phosphorylates IRS1 (Sus scrofa)
ADP [cytosol]
Active ALK phosphorylates JAK3 (Sus scrofa)
ADP [cytosol]
Active ALK phosphorylates PLCG1 (Sus scrofa)
ADP [cytosol]
Active ALK phosphorylates SHC1 (Sus scrofa)
ADP [cytosol]
PI3K synthesizes PIP3 downstream of ALK (Sus scrofa)
ADP [cytosol]
Signaling by EGFR (Sus scrofa)
EGFR autophosphorylation (Sus scrofa)
ADP [cytosol]
EGFR downregulation (Sus scrofa)
EGFR phosphorylates EPS15 (Sus scrofa)
ADP [cytosol]
Phosphorylation of CBL (EGFR:CBL) (Sus scrofa)
ADP [cytosol]
Phosphorylation of CBL (EGFR:GRB2:CBL) (Sus scrofa)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Sus scrofa)
EGFR activates PLC-gamma1 by phosphorylation (Sus scrofa)
ADP [cytosol]
GAB1 signalosome (Sus scrofa)
GAB1 phosphorylation by EGFR kinase (Sus scrofa)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Sus scrofa)
ADP [cytosol]
Phosphorylation of EGFR by SRC kinase (Sus scrofa)
ADP [cytosol]
SHC1 events in EGFR signaling (Sus scrofa)
SHC1 phosphorylation by phosphorylated EGFR (Sus scrofa)
ADP [cytosol]
Signaling by ERBB2 (Sus scrofa)
ERBB2 Activates PTK6 Signaling (Sus scrofa)
ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)
ADP [cytosol]
PI3K events in ERBB2 signaling (Sus scrofa)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Sus scrofa)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Sus scrofa)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Sus scrofa)
Activated PKC phosphorylates SHC1 (Sus scrofa)
ADP [cytosol]
SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)
ADP [cytosol]
SRC family kinases phosphorylate ERBB2 (Sus scrofa)
ADP [cytosol]
Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)
ADP [cytosol]
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Sus scrofa)
ADP [cytosol]
Signaling by ERBB4 (Sus scrofa)
PI3K events in ERBB4 signaling (Sus scrofa)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Sus scrofa)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Sus scrofa)
Phosphorylation of SHC1 by ERBB4 homodimers (Sus scrofa)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Sus scrofa)
ADP [cytosol]
Signaling by FGFR (Sus scrofa)
Signaling by FGFR1 (Sus scrofa)
Downstream signaling of activated FGFR1 (Sus scrofa)
FRS-mediated FGFR1 signaling (Sus scrofa)
Activated FGFR1 phosphorylates FRS2 (Sus scrofa)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Sus scrofa)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Sus scrofa)
ADP [cytosol]
PI-3K cascade:FGFR1 (Sus scrofa)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Sus scrofa)
Activated FGFR1 phosphorylates PLCG1 (Sus scrofa)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Sus scrofa)
Activated FGFR1 phosphorylates SHC1 (Sus scrofa)
ADP [cytosol]
FGFR1 ligand binding and activation (Sus scrofa)
FGFR1b ligand binding and activation (Sus scrofa)
Autocatalytic phosphorylation of FGFR1b (Sus scrofa)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Sus scrofa)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Sus scrofa)
ADP [cytosol]
FGFR1c ligand binding and activation (Sus scrofa)
Autocatalytic phosphorylation of FGFR1c (Sus scrofa)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Sus scrofa)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Sus scrofa)
ADP [cytosol]
Spry regulation of FGF signaling (Sus scrofa)
SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)
ADP [cytosol]
Signaling by FGFR2 (Sus scrofa)
Downstream signaling of activated FGFR2 (Sus scrofa)
FRS-mediated FGFR2 signaling (Sus scrofa)
Activated FGFR2 phosphorylates PPTN11 (Sus scrofa)
ADP [cytosol]
PI-3K cascade:FGFR2 (Sus scrofa)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)
ADP [cytosol]
Signaling by FGFR3 (Sus scrofa)
Downstream signaling of activated FGFR3 (Sus scrofa)
FRS-mediated FGFR3 signaling (Sus scrofa)
Activated FGFR3 phosphorylates PPTN11 (Sus scrofa)
ADP [cytosol]
PI-3K cascade:FGFR3 (Sus scrofa)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Sus scrofa)
Spry regulation of FGF signaling (Sus scrofa)
SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)
ADP [cytosol]
Signaling by FGFR4 (Sus scrofa)
Downstream signaling of activated FGFR4 (Sus scrofa)
FRS-mediated FGFR4 signaling (Sus scrofa)
Activated FGFR4 phosphorylates FRS2 (Sus scrofa)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Sus scrofa)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Sus scrofa)
ADP [cytosol]
PI-3K cascade:FGFR4 (Sus scrofa)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Sus scrofa)
Activated FGFR4 phosphorylates PLCG1 (Sus scrofa)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Sus scrofa)
Activated FGFR4 phosphorylates SHC1 (Sus scrofa)
ADP [cytosol]
FGFR4 ligand binding and activation (Sus scrofa)
Autocatalytic phosphorylation of FGFR4 (Sus scrofa)
ADP [cytosol]
betaKlotho-mediated ligand binding (Sus scrofa)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Sus scrofa)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Sus scrofa)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Sus scrofa)
ADP [cytosol]
Spry regulation of FGF signaling (Sus scrofa)
SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)
ADP [cytosol]
SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)
ADP [cytosol]
Signaling by Insulin receptor (Sus scrofa)
Autophosphorylation of insulin receptor (Sus scrofa)
ADP [cytosol]
Insulin receptor signalling cascade (Sus scrofa)
IRS activation (Sus scrofa)
Phosphorylation of IRS (Sus scrofa)
ADP [cytosol]
IRS-mediated signalling (Sus scrofa)
PI3K Cascade (Sus scrofa)
Activation of AKT2 (Sus scrofa)
PDPK1 phosphorylates AKT2 (Sus scrofa)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of SHC1 (Sus scrofa)
ADP [cytosol]
Signal attenuation (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Sus scrofa)
ADP [cytosol]
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)
ADP [cytosol]
Signaling by MET (Sus scrofa)
MET Receptor Activation (Sus scrofa)
MET dimers autophosphorylate (Sus scrofa)
ADP [cytosol]
MET activates PI3K/AKT signaling (Sus scrofa)
MET bound PI3K generates PIP3 (Sus scrofa)
ADP [cytosol]
MET phosphorylates GAB1 (Sus scrofa)
ADP [cytosol]
MET activates RAS signaling (Sus scrofa)
MET phosphorylates SHC1-2 (Sus scrofa)
ADP [cytosol]
MET activates STAT3 (Sus scrofa)
MET phosphorylates STAT3 (Sus scrofa)
ADP [cytosol]
MET promotes cell motility (Sus scrofa)
MET activates PTK2 signaling (Sus scrofa)
MET phosphorylates PTK2 (Sus scrofa)
ADP [cytosol]
SRC phosphorylates PTK2 (Sus scrofa)
ADP [cytosol]
Negative regulation of MET activity (Sus scrofa)
MET phosphorylates CBL (Sus scrofa)
ADP [cytosol]
Signaling by MST1 (Sus scrofa)
MST1R autophosphorylates (Sus scrofa)
ADP [cytosol]
Signaling by NTRKs (Sus scrofa)
Signaling by NTRK1 (TRKA) (Sus scrofa)
PI3K/AKT activation (Sus scrofa)
PI3K produces PIP3 and other phosphatidyl inositides (Sus scrofa)
ADP [cytosol]
Signalling to ERKs (Sus scrofa)
Prolonged ERK activation events (Sus scrofa)
ARMS-mediated activation (Sus scrofa)
ARMS is phosphorylated by active TrkA receptor (Sus scrofa)
ADP [cytosol]
Frs2-mediated activation (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
ADP [cytosol]
BRAF autophosphorylates downstream of RAP1 and NGF (Sus scrofa)
ADP [cytosol]
FRS2 is phosphorylated by active TrkA receptor (Sus scrofa)
ADP [cytosol]
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
ADP [cytosol]
Signalling to RAS (Sus scrofa)
p38MAPK events (Sus scrofa)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Sus scrofa)
ADP [cytosol]
Signaling by NTRK3 (TRKC) (Sus scrofa)
Activated NTRK3 signals through PI3K (Sus scrofa)
Activated NTRK3 promotes SRC autophosphorylation (Sus scrofa)
ADP [cytosol]
NTF3 activates NTRK3 signaling (Sus scrofa)
NTRK3 dimers trans-autophosphorylate (Sus scrofa)
ADP [cytosol]
Signaling by PDGF (Sus scrofa)
Autophosphorylation of PDGF alpha receptors (Sus scrofa)
ADP [cytosol]
Autophosphorylation of PDGF alpha/beta receptors (Sus scrofa)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Sus scrofa)
ADP [cytosol]
Downstream signal transduction (Sus scrofa)
Activation of Src (Sus scrofa)
ADP [cytosol]
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Sus scrofa)
ADP [cytosol]
Signaling by SCF-KIT (Sus scrofa)
Autophosphorylation of KIT (Sus scrofa)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Sus scrofa)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Sus scrofa)
ADP [cytosol]
Phosphorylation of JAK2 (Sus scrofa)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Sus scrofa)
ADP [cytosol]
Phosphorylation of STATs (Sus scrofa)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Sus scrofa)
ADP [cytosol]
Regulation of KIT signaling (Sus scrofa)
PKC alpha interacts with and phosphorylates KIT (Sus scrofa)
ADP [cytosol]
Phosphorylation of APS (Sus scrofa)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Sus scrofa)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Sus scrofa)
IGF1,2:IGF1R autophosphorylates (Sus scrofa)
ADP [cytosol]
IGF1R signaling cascade (Sus scrofa)
IRS-related events triggered by IGF1R (Sus scrofa)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Sus scrofa)
ADP [cytosol]
IRS-mediated signalling (Sus scrofa)
PI3K Cascade (Sus scrofa)
Activation of AKT2 (Sus scrofa)
PDPK1 phosphorylates AKT2 (Sus scrofa)
ADP [cytosol]
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
SHC-related events triggered by IGF1R (Sus scrofa)
IGF1R phosphorylates SHC1 (Sus scrofa)
ADP [cytosol]
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
AXL autophosphorylates on Y779 and Y821 (Sus scrofa)
ADP [cytosol]
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Sus scrofa)
ADP [cytosol]
FYN autophosphorylates (Sus scrofa)
ADP [cytosol]
FYN phosphorylates PAK2 (Sus scrofa)
ADP [cytosol]
PAK2 autophorylates (Sus scrofa)
ADP [cytosol]
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Sus scrofa)
ADP [cytosol]
PTK2 autophosphorylates (Sus scrofa)
ADP [cytosol]
Phosphorylation of SRC-1 (Sus scrofa)
ADP [cytosol]
SRC-1 phosphorylates PTK2-beta (Sus scrofa)
ADP [cytosol]
SRC-1 phosphorylates SHB (Sus scrofa)
ADP [cytosol]
SRC-1 phosphorylates p-Y397-PTK2 (Sus scrofa)
ADP [cytosol]
Src kinases phosphorylate VAV (Sus scrofa)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
ADP [cytosol]
VEGFR2 autophosphorylates (Sus scrofa)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Sus scrofa)
PDK1 phosphorylates PKC (Sus scrofa)
ADP [cytosol]
PKC autophosphorylates (Sus scrofa)
ADP [cytosol]
PKC phosphorylates sphingosine kinase 1 (Sus scrofa)
ADP [cytosol]
SFKs phosphorylate PLCG1 (Sus scrofa)
ADP [cytosol]
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Sus scrofa)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
ADP [cytosol]
PAK1-3 autophosphorylates (Sus scrofa)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Sus scrofa)
ADP [cytosol]
p-MAPK2/3 phosphorylates HSP27 (Sus scrofa)
ADP [cytosol]
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Sus scrofa)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Sus scrofa)
ADP [cytosol]
p38 MAPK activation by VEGFR (Sus scrofa)
ADP [cytosol]
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Sus scrofa)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate Formins (Sus scrofa)
AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)
ADP [cytosol]
RHO GTPases Activate NADPH Oxidases (Sus scrofa)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Sus scrofa)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Sus scrofa)
ADP [cytosol]
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Sus scrofa)
ADP [cytosol]
PKC phosphorylates NCF1 (Sus scrofa)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Sus scrofa)
ABL phosphorylates WAVEs (Sus scrofa)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Sus scrofa)
Mother filament:ARP2/3:actin:ADP [cytosol] (Sus scrofa)
Actin:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
Detachment of WASP/WAVE (Sus scrofa)
Mother filament:ARP2/3:actin:ADP [cytosol] (Sus scrofa)
Actin:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Sus scrofa)
ADP [cytosol]
RHO GTPases activate PAKs (Sus scrofa)
Autophosphorylation of PAK1,2,3 (Sus scrofa)
ADP [cytosol]
PAK1 or PAK2 phosphorylates MYLK (Sus scrofa)
ADP [cytosol]
PAK1 phosphorylates FLNA (Sus scrofa)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Sus scrofa)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Sus scrofa)
ADP [cytosol]
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Sus scrofa)
ADP [cytosol]
RHO GTPases activate PKNs (Sus scrofa)
PDPK1 phosphorylates PKN1,2,3 (Sus scrofa)
ADP [cytosol]
p-T774-PKN1 phosphorylates CDC25C (Sus scrofa)
ADP [cytosol]
p-T774-PKN1 phosphorylates PPP1R14A (Sus scrofa)
ADP [cytosol]
Signaling by TGFB family members (Sus scrofa)
Signaling by Activin (Sus scrofa)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Sus scrofa)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Sus scrofa)
ADP [cytosol]
Signaling by BMP (Sus scrofa)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Sus scrofa)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Sus scrofa)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Sus scrofa)
TGF-beta receptor signaling activates SMADs (Sus scrofa)
Activated type I receptor phosphorylates SMAD2/3 directly (Sus scrofa)
ADP [cytosol]
TGFBR2 phosphorylates TGFBR1 (Sus scrofa)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Sus scrofa)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Sus scrofa)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Sus scrofa)
ADP [cytosol]
Signaling by WNT (Sus scrofa)
Beta-catenin independent WNT signaling (Sus scrofa)
Ca2+ pathway (Sus scrofa)
Activation of NLK (Sus scrofa)
ADP [cytosol]
Autophosphorylation and activation of CAMK2 (Sus scrofa)
ADP [cytosol]
Dissociation of CaM and CAMK2 autophosphorylation (Sus scrofa)
ADP [cytosol]
PCP/CE pathway (Sus scrofa)
WNT5A-dependent internalization of FZD4 (Sus scrofa)
DVL2 is phosphorylated by PKC (Sus scrofa)
ADP [cytosol]
Degradation of beta-catenin by the destruction complex (Sus scrofa)
AXIN is phosphorylated in the destruction complex (Sus scrofa)
ADP [cytosol]
Beta-catenin phosphorylation cascade (Sus scrofa)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Sus scrofa)
ADP [cytosol]
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Sus scrofa)
ADP [cytosol]
Phosphorylation of APC component of the destruction complex (Sus scrofa)
ADP [cytosol]
TCF dependent signaling in response to WNT (Sus scrofa)
Disassembly of the destruction complex and recruitment of AXIN to the membrane (Sus scrofa)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Sus scrofa)
ADP [cytosol]
WNT mediated activation of DVL (Sus scrofa)
CSNK2-mediated phosphorylation of DVL (Sus scrofa)
ADP [cytosol]
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Sus scrofa)
ADP [cytosol]
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Sus scrofa)
ADP [cytosol]
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
ABC transporters in lipid homeostasis (Sus scrofa)
ABCA12 transports lipids from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCA3 transports PC, PG from ER membrane to lamellar body (Sus scrofa)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Sus scrofa)
ADP [cytosol]
ABCA7:Apo1A-mediated phospholipid efflux (Sus scrofa)
ADP [cytosol]
ABCAs mediate lipid efflux (Sus scrofa)
ADP [cytosol]
ABCAs mediate lipid influx (Sus scrofa)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Sus scrofa)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
ADP [cytosol]
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCA4 mediates atRAL transport (Sus scrofa)
ADP [cytosol]
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
ABCB4 transports PC from plasma membrane to extracellular region (Sus scrofa)
ADP [cytosol]
ABCB9 transports peptides from cytosol to lysosomal lumen (Sus scrofa)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
HCO3- transport through ion channel (Sus scrofa)
ADP [cytosol]
Mitochondrial ABC transporters (Sus scrofa)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Sus scrofa)
ADP [cytosol]
The ABCC family mediates organic anion transport (Sus scrofa)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)
ADP [cytosol]
Aquaporin-mediated transport (Sus scrofa)
Vasopressin regulates renal water homeostasis via Aquaporins (Sus scrofa)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Sus scrofa)
ADP [cytosol]
Ion channel transport (Sus scrofa)
Ion transport by P-type ATPases (Sus scrofa)
ATP12A:ATP4B exchanges K+ for H+ (Sus scrofa)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Sus scrofa)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Sus scrofa)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Sus scrofa)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Sus scrofa)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Sus scrofa)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Sus scrofa)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Sus scrofa)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Sus scrofa)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Sus scrofa)
ADP [cytosol]
Iron uptake and transport (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
ADP [cytosol]
Transferrin endocytosis and recycling (Sus scrofa)
Acidification of Tf:TfR1 containing endosome (Sus scrofa)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Sus scrofa)
Plasma lipoprotein assembly (Sus scrofa)
HDL assembly (Sus scrofa)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Sus scrofa)
ADP [cytosol]
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Sus scrofa)
ADP [cytosol]
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Sus scrofa)
ADP [cytosol]
Plasma lipoprotein remodeling (Sus scrofa)
HDL remodeling (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
ADP [cytosol]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
ADP [cytosol]
Vesicle-mediated transport (Sus scrofa)
Membrane Trafficking (Sus scrofa)
Clathrin-mediated endocytosis (Sus scrofa)
AAK1 phosphorylates AP-2 mu subunit at T156 (Sus scrofa)
ADP [cytosol]
Cargo recognition for clathrin-mediated endocytosis (Sus scrofa)
ADBRK1,2 phosphorylate AVPR2 (Sus scrofa)
ADP [cytosol]
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
ADP [cytosol]
HSPA8-mediated ATP hydrolysis promotes vesicle uncoating (Sus scrofa)
clathrin:HSPA8:ADP [cytosol] (Sus scrofa)
HSPA8:ADP [cytosol] (Sus scrofa)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Sus scrofa)
ADP [cytosol]
ER to Golgi Anterograde Transport (Sus scrofa)
COPI-mediated anterograde transport (Sus scrofa)
GBF1 stimulates ARF nucleotide exchange (Sus scrofa)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Sus scrofa)
ESCRT Disassembly (Sus scrofa)
ADP [cytosol]
Gap junction trafficking and regulation (Sus scrofa)
Regulation of gap junction activity (Sus scrofa)
Phosphorylation of Cx43 by c-src (Sus scrofa)
ADP [cytosol]
Intra-Golgi and retrograde Golgi-to-ER traffic (Sus scrofa)
Intra-Golgi traffic (Sus scrofa)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Sus scrofa)
ADP [cytosol]
Rab regulation of trafficking (Sus scrofa)
RAB GEFs exchange GTP for GDP on RABs (Sus scrofa)
p-ULK1 phosphorylates DENND3 (Sus scrofa)
ADP [cytosol]
Autophagy (Xenopus tropicalis)
Macroautophagy (Xenopus tropicalis)
AMPK (complex) phosphorylates ULK1 (complex) (Xenopus tropicalis)
ADP [cytosol]
Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)
ADP [cytosol]
Beclin-1 complex phosphorylates PtdIns (Xenopus tropicalis)
ADP [cytosol]
Selective autophagy (Xenopus tropicalis)
Mitophagy (Xenopus tropicalis)
Receptor Mediated Mitophagy (Xenopus tropicalis)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Xenopus tropicalis)
ADP [cytosol]
Thr-180 of ULK1 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Xenopus tropicalis)
ADP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Xenopus tropicalis)
ADP [cytosol]
ULK1 phosphorylates Beclin-1 (Xenopus tropicalis)
ADP [cytosol]
Cell Cycle (Xenopus tropicalis)
Cell Cycle, Mitotic (Xenopus tropicalis)
M Phase (Xenopus tropicalis)
Mitotic Metaphase and Anaphase (Xenopus tropicalis)
Mitotic Anaphase (Xenopus tropicalis)
Nuclear Envelope (NE) Reassembly (Xenopus tropicalis)
Initiation of Nuclear Envelope (NE) Reformation (Xenopus tropicalis)
CDK1 phosphorylates LBR (Xenopus tropicalis)
ADP [cytosol]
Sealing of the nuclear envelope (NE) by ESCRT-III (Xenopus tropicalis)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Xenopus tropicalis)
ADP [cytosol]
Mitotic Prometaphase (Xenopus tropicalis)
EML4 and NUDC in mitotic spindle formation (Xenopus tropicalis)
PLK1 phosphorylates NUDC (Xenopus tropicalis)
ADP [cytosol]
Resolution of Sister Chromatid Cohesion (Xenopus tropicalis)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Xenopus tropicalis)
ADP [cytosol]
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at centromeres (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of cohesin by PLK1 at chromosomal arms (Xenopus tropicalis)
ADP [cytosol]
Mitotic Prophase (Xenopus tropicalis)
Golgi Cisternae Pericentriolar Stack Reorganization (Xenopus tropicalis)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Xenopus tropicalis)
ADP [cytosol]
PLK1 phosphorylates GORASP1 (Xenopus tropicalis)
ADP [cytosol]
Nuclear Envelope Breakdown (Xenopus tropicalis)
Nuclear Pore Complex (NPC) Disassembly (Xenopus tropicalis)
CDK1 phosphorylates NUP98 (Xenopus tropicalis)
ADP [cytosol]
Mitotic G1 phase and G1/S transition (Xenopus tropicalis)
G1 Phase (Xenopus tropicalis)
Cyclin D associated events in G1 (Xenopus tropicalis)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Xenopus tropicalis)
ADP [cytosol]
G1/S Transition (Xenopus tropicalis)
Cyclin E associated events during G1/S transition (Xenopus tropicalis)
SCF(Skp2)-mediated degradation of p27/p21 (Xenopus tropicalis)
PTK6 phosphorylates CDKN1B (Xenopus tropicalis)
ADP [cytosol]
Mitotic G2-G2/M phases (Xenopus tropicalis)
G2/M Transition (Xenopus tropicalis)
AURKA Activation by TPX2 (Xenopus tropicalis)
TPX2 promotes AURKA autophosphorylation (Xenopus tropicalis)
ADP [cytosol]
Centrosome maturation (Xenopus tropicalis)
Loss of proteins required for interphase microtubule organization from the centrosome (Xenopus tropicalis)
Loss of Nlp from mitotic centrosomes (Xenopus tropicalis)
Plk1-mediated phosphorylation of Nlp (Xenopus tropicalis)
ADP [cytosol]
Cyclin A/B1/B2 associated events during G2/M transition (Xenopus tropicalis)
Phosphorylation of Cyclin B1 in the CRS domain (Xenopus tropicalis)
ADP [cytosol]
Interaction between PHLDA1 and AURKA (Xenopus tropicalis)
AURKA phosphorylates PHLDA1 (Xenopus tropicalis)
ADP [cytosol]
Regulation of PLK1 Activity at G2/M Transition (Xenopus tropicalis)
AJUBA facilitates AURKA autophosphorylation (Xenopus tropicalis)
ADP [cytosol]
AURKA phosphorylates PLK1 (Xenopus tropicalis)
ADP [cytosol]
CDK1 phosphorylates BORA (Xenopus tropicalis)
ADP [cytosol]
PLK1 phosphorylates BORA (Xenopus tropicalis)
ADP [cytosol]
PLK1 phosphorylates OPTN (Xenopus tropicalis)
ADP [cytosol]
The role of GTSE1 in G2/M progression after G2 checkpoint (Xenopus tropicalis)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Xenopus tropicalis)
ADP [cytosol]
PLK1 phosphorylates GTSE1 (Xenopus tropicalis)
ADP [cytosol]
S Phase (Xenopus tropicalis)
Cyclin A:Cdk2-associated events at S phase entry (Xenopus tropicalis)
SCF(Skp2)-mediated degradation of p27/p21 (Xenopus tropicalis)
PTK6 phosphorylates CDKN1B (Xenopus tropicalis)
ADP [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to heat stress (Xenopus tropicalis)
Regulation of HSF1-mediated heat shock response (Xenopus tropicalis)
HSP110s exchange ATP for ADP on HSP70s:ADP (Xenopus tropicalis)
ADP [cytosol]
HSP70s:ADP [cytosol] (Xenopus tropicalis)
HSP13:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP14:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1B:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA2:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA4:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA5:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA6:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA8:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA9:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP40s activate intrinsic ATPase activity of HSP70s in the cytosol (Xenopus tropicalis)
HSP70s:ADP [cytosol] (Xenopus tropicalis)
HSP13:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP14:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA12A:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA12B:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1A:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1B:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA1L:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA2:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA4:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA5:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA6:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA8:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSPA9:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP90 chaperone cycle for steroid hormone receptors (SHR) in the presence of ligand (Xenopus tropicalis)
ATP binding to HSP90 triggers conformation change (Xenopus tropicalis)
HSP90:ATP:STIP1:HSP70:nascent protein [cytosol] (Xenopus tropicalis)
HSP70:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Xenopus tropicalis)
HSP70:ADP:nascent protein [cytosol] (Xenopus tropicalis)
HSP70:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
ATP hydrolysis by HSP70 (Xenopus tropicalis)
HSP40:HSP70:ADP:nascent protein [cytosol] (Xenopus tropicalis)
ADP [cytosol]
STIP1(HOP) binds HSP90 and HSP70:HSP40:nascent protein (Xenopus tropicalis)
HSP40:HSP70:ADP:nascent protein [cytosol] (Xenopus tropicalis)
ADP [cytosol]
HSP90:STIP1:HSP70:nascent protein [cytosol] (Xenopus tropicalis)
HSP70:ADP:nascent protein [cytosol] (Xenopus tropicalis)
HSP70:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Unfolded Protein Response (UPR) (Xenopus tropicalis)
IRE1alpha activates chaperones (Xenopus tropicalis)
IRE1 dimer autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
PERK regulates gene expression (Xenopus tropicalis)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Xenopus tropicalis)
ADP [cytosol]
DNA Replication (Xenopus tropicalis)
DNA Replication Pre-Initiation (Xenopus tropicalis)
Assembly of the pre-replicative complex (Xenopus tropicalis)
Assembly of the ORC complex at the origin of replication (Xenopus tropicalis)
ORC6 is phosphorylated on T195 (Xenopus tropicalis)
ADP [cytosol]
Developmental Biology (Xenopus tropicalis)
Nervous system development (Xenopus tropicalis)
Axon guidance (Xenopus tropicalis)
EPH-Ephrin signaling (Xenopus tropicalis)
EPH receptors autophosphorylate (Xenopus tropicalis)
ADP [cytosol]
EPH-ephrin mediated repulsion of cells (Xenopus tropicalis)
SFKs phosphorylate VAV2,3 (Xenopus tropicalis)
ADP [cytosol]
EPHB-mediated forward signaling (Xenopus tropicalis)
EPHB phosphorylates TIAM1 (Xenopus tropicalis)
ADP [cytosol]
PAK1 autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
p-EPHB phosphorylates SDC2 (Xenopus tropicalis)
ADP [cytosol]
Ephrin signaling (Xenopus tropicalis)
PAKs autophosphorylate (Xenopus tropicalis)
ADP [cytosol]
PAKs phosphorylate MLC (Xenopus tropicalis)
ADP [cytosol]
L1CAM interactions (Xenopus tropicalis)
Recycling pathway of L1 (Xenopus tropicalis)
Phosphorylation of L1 by ERK (Xenopus tropicalis)
ADP [cytosol]
Signal transduction by L1 (Xenopus tropicalis)
Interaction of PAK1 with Rac1-GTP (Xenopus tropicalis)
ADP [cytosol]
Netrin-1 signaling (Xenopus tropicalis)
DCC mediated attractive signaling (Xenopus tropicalis)
Phosphorylation of DCC by Fyn (Xenopus tropicalis)
ADP [cytosol]
RET signaling (Xenopus tropicalis)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
Semaphorin interactions (Xenopus tropicalis)
CRMPs in Sema3A signaling (Xenopus tropicalis)
Phosphorylation of CRMPs by Cdk5 (Xenopus tropicalis)
ADP [cytosol]
Tyrosine phosphorylation of CRMPs by Fes (Xenopus tropicalis)
ADP [cytosol]
Sema3A PAK dependent Axon repulsion (Xenopus tropicalis)
Autophosphorylation of PAK (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of LIMK-1 by PAK (Xenopus tropicalis)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Xenopus tropicalis)
ADP [cytosol]
Sema4D in semaphorin signaling (Xenopus tropicalis)
Sema4D mediated inhibition of cell attachment and migration (Xenopus tropicalis)
SEMA4D interacts with Plexin-B1:Met (Xenopus tropicalis)
ADP [cytosol]
Drug ADME (Xenopus tropicalis)
Aspirin ADME (Xenopus tropicalis)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Xenopus tropicalis)
ADP [cytosol]
Azathioprine ADME (Xenopus tropicalis)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
GUK1 phosphorylates 6TGMP to 6TGDP (Xenopus tropicalis)
ADP [cytosol]
GUK1 phosphorylates 6TdGMP to 6TdGDP (Xenopus tropicalis)
ADP [cytosol]
Ciprofloxacin ADME (Xenopus tropicalis)
ABCG2 transports Cipro from hepatic cell to extracellular space (Xenopus tropicalis)
ADP [cytosol]
ABCG2 transports Cipro from intestinal cell to extracellular space (Xenopus tropicalis)
ADP [cytosol]
Paracetamol ADME (Xenopus tropicalis)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Xenopus tropicalis)
ADP [cytosol]
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Xenopus tropicalis)
ADP [cytosol]
Ribavirin ADME (Xenopus tropicalis)
ADK phosphorylates RBV (Xenopus tropicalis)
ADP [cytosol]
NME1,2 hexamers phosphorylate RBV-DP (Xenopus tropicalis)
ADP [cytosol]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional Regulation by TP53 (Xenopus tropicalis)
TP53 Regulates Transcription of Cell Cycle Genes (Xenopus tropicalis)
TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain (Xenopus tropicalis)
PLK2 phosphorylates NPM1 (Xenopus tropicalis)
ADP [cytosol]
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Xenopus tropicalis)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Xenopus tropicalis)
ADP [cytosol]
Hemostasis (Xenopus tropicalis)
Factors involved in megakaryocyte development and platelet production (Xenopus tropicalis)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Xenopus tropicalis)
ADP [cytosol]
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Xenopus tropicalis)
ADP [cytosol]
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Xenopus tropicalis)
ADP [cytosol]
Kinesins (Xenopus tropicalis)
Kinesins move along microtubules consuming ATP (Xenopus tropicalis)
ADP [cytosol]
Platelet activation, signaling and aggregation (Xenopus tropicalis)
Effects of PIP2 hydrolysis (Xenopus tropicalis)
DAG kinase produces phosphatidic acid from DAG (Xenopus tropicalis)
ADP [cytosol]
GPVI-mediated activation cascade (Xenopus tropicalis)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Xenopus tropicalis)
ADP [cytosol]
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
SYK autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
Syk activation leads to SLP-76 activation (Xenopus tropicalis)
ADP [cytosol]
Response to elevated platelet cytosolic Ca2+ (Xenopus tropicalis)
Disinhibition of SNARE formation (Xenopus tropicalis)
Phosphorylation of Platelet Sec-1 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of Syntaxin-4 (Xenopus tropicalis)
ADP [cytosol]
Signal amplification (Xenopus tropicalis)
ADP signalling through P2Y purinoceptor 1 (Xenopus tropicalis)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Xenopus tropicalis)
ADP [cytosol]
Platelet homeostasis (Xenopus tropicalis)
Platelet sensitization by LDL (Xenopus tropicalis)
Fgr may phosphorylate p38 MAPK (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of cPLA2 by MAPK p38 alpha (Xenopus tropicalis)
ADP [cytosol]
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Costimulation by the CD28 family (Xenopus tropicalis)
CD28 co-stimulation (Xenopus tropicalis)
CD28 dependent PI3K/Akt signaling (Xenopus tropicalis)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
p-S400-Cot phosphorylates NIK (Xenopus tropicalis)
ADP [cytosol]
CD28 dependent Vav1 pathway (Xenopus tropicalis)
Activation of Vav1 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of CD28 (Xenopus tropicalis)
ADP [cytosol]
Rap1 signalling (Xenopus tropicalis)
PKA/PKG phosphorylate Rap1GAP2 (Xenopus tropicalis)
ADP [cytosol]
Signaling by the B Cell Receptor (BCR) (Xenopus tropicalis)
Antigen activates B Cell Receptor (BCR) leading to generation of second messengers (Xenopus tropicalis)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
Downstream signaling events of B Cell Receptor (BCR) (Xenopus tropicalis)
Activation of NF-kappaB in B cells (Xenopus tropicalis)
PRKCB (PKC-beta) phosphorylates CARMA1 (Xenopus tropicalis)
ADP [cytosol]
TCR signaling (Xenopus tropicalis)
Generation of second messenger molecules (Xenopus tropicalis)
Phosphorylation of PLC-gamma1 (Xenopus tropicalis)
ADP [cytosol]
Cytokine Signaling in Immune system (Xenopus tropicalis)
Growth hormone receptor signaling (Xenopus tropicalis)
JAK2 phosphorylation (Xenopus tropicalis)
ADP [cytosol]
Interferon Signaling (Xenopus tropicalis)
Antiviral mechanism by IFN-stimulated genes (Xenopus tropicalis)
PKR-mediated signaling (Xenopus tropicalis)
p-PKR dimer phosphorylates CDK1 (Xenopus tropicalis)
ADP [cytosol]
p-PKR dimer phosphorylates DHX9 (Xenopus tropicalis)
ADP [cytosol]
p-PKR dimer phosphorylates ILF3:ILF2 (Xenopus tropicalis)
ADP [cytosol]
p-PKR dimer phosphorylates MKK6 (Xenopus tropicalis)
ADP [cytosol]
p-PKR dimer phosphorylates SNCA (Xenopus tropicalis)
ADP [cytosol]
Interferon alpha/beta signaling (Xenopus tropicalis)
Activation of JAK kinases (Xenopus tropicalis)
ADP [cytosol]
Formation of p-STAT1 homodimer (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of INFAR1 by TYK2 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of STAT2 (Xenopus tropicalis)
ADP [cytosol]
Interferon gamma signaling (Xenopus tropicalis)
JAK2-activated MAPKs phosphorylate YBX1 (Xenopus tropicalis)
ADP [cytosol]
Prolactin receptor signaling (Xenopus tropicalis)
JAK2 phosphorylation (Xenopus tropicalis)
ADP [cytosol]
PRLR is phosphorylated at Ser-349 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Interleukins (Xenopus tropicalis)
Interleukin-1 family signaling (Xenopus tropicalis)
Interleukin-1 signaling (Xenopus tropicalis)
IRAK4 is activated by autophosphorylation (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Xenopus tropicalis)
ADP [cytosol]
Interleukin-37 signaling (Xenopus tropicalis)
STAT3 phosphorylation (Xenopus tropicalis)
ADP [cytosol]
TBK1 phosphorylation (Xenopus tropicalis)
ADP [cytosol]
Interleukin-10 signaling (Xenopus tropicalis)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Xenopus tropicalis)
ADP [cytosol]
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Xenopus tropicalis)
ADP [cytosol]
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Xenopus tropicalis)
ADP [cytosol]
Interleukin-12 family signaling (Xenopus tropicalis)
Interleukin-27 signaling (Xenopus tropicalis)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Xenopus tropicalis)
ADP [cytosol]
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Xenopus tropicalis)
ADP [cytosol]
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Xenopus tropicalis)
ADP [cytosol]
Interleukin-35 Signalling (Xenopus tropicalis)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
ADP [cytosol]
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Xenopus tropicalis)
ADP [cytosol]
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Xenopus tropicalis)
ADP [cytosol]
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Xenopus tropicalis)
ADP [cytosol]
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Xenopus tropicalis)
ADP [cytosol]
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Xenopus tropicalis)
ADP [cytosol]
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
Interleukin-17 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Interleukin-20 family signaling (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
ADP [cytosol]
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Xenopus tropicalis)
ADP [cytosol]
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Xenopus tropicalis)
ADP [cytosol]
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
ADP [cytosol]
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Xenopus tropicalis)
ADP [cytosol]
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Xenopus tropicalis)
ADP [cytosol]
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Xenopus tropicalis)
ADP [cytosol]
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Xenopus tropicalis)
ADP [cytosol]
Interleukin-6 family signaling (Xenopus tropicalis)
Interleukin-6 signaling (Xenopus tropicalis)
IL6ST is tyrosine phosphorylated (Xenopus tropicalis)
ADP [cytosol]
JAK activation (Xenopus tropicalis)
ADP [cytosol]
PTPN11 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
Serine phosphorylation of STATs (Xenopus tropicalis)
ADP [cytosol]
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Xenopus tropicalis)
ADP [cytosol]
TNFR2 non-canonical NF-kB pathway (Xenopus tropicalis)
NIK-->noncanonical NF-kB signaling (Xenopus tropicalis)
Active NIK phosphorylates IKKA dimer (Xenopus tropicalis)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)
ADP [cytosol]
NIK autophosphorylates on T559 (Xenopus tropicalis)
ADP [cytosol]
Innate Immune System (Xenopus tropicalis)
Alpha-protein kinase 1 signaling pathway (Xenopus tropicalis)
ALPK1 phosphorylates TIFA (Xenopus tropicalis)
ADP [cytosol]
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Xenopus tropicalis)
ADP [cytosol]
Antimicrobial peptides (Xenopus tropicalis)
Ion influx/efflux at host-pathogen interface (Xenopus tropicalis)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Xenopus tropicalis)
ADP [cytosol]
C-type lectin receptors (CLRs) (Xenopus tropicalis)
CD209 (DC-SIGN) signaling (Xenopus tropicalis)
PAK phosphorylates p21 RAF1 on S338 (Xenopus tropicalis)
ADP [cytosol]
SFKs phosphorylates RAF1 on Y340,Y341 (Xenopus tropicalis)
ADP [cytosol]
CLEC7A (Dectin-1) signaling (Xenopus tropicalis)
Dectin-1 mediated noncanonical NF-kB signaling (Xenopus tropicalis)
Active NIK phosphorylates IKKA dimer (Xenopus tropicalis)
ADP [cytosol]
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)
ADP [cytosol]
PKC-delta phosphorylates CARD9 (Xenopus tropicalis)
ADP [cytosol]
Dectin-2 family (Xenopus tropicalis)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Xenopus tropicalis)
ADP [cytosol]
Cytosolic sensors of pathogen-associated DNA (Xenopus tropicalis)
STING mediated induction of host immune responses (Xenopus tropicalis)
STAT6-mediated induction of chemokines (Xenopus tropicalis)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Xenopus tropicalis)
ADP [cytosol]
TBK1 phosphorylates STAT6 at Ser407 (Xenopus tropicalis)
ADP [cytosol]
p-S407-STAT6 is phosphorylated at Tyr641 (Xenopus tropicalis)
ADP [cytosol]
DAP12 interactions (Xenopus tropicalis)
DAP12 signaling (Xenopus tropicalis)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Xenopus tropicalis)
ADP [cytosol]
Fc epsilon receptor (FCERI) signaling (Xenopus tropicalis)
Autophosphorylation of LYN kinase (Xenopus tropicalis)
ADP [cytosol]
FCERI mediated Ca+2 mobilization (Xenopus tropicalis)
Autophosphorylation of BTK/ITK (Xenopus tropicalis)
ADP [cytosol]
FCERI mediated MAPK activation (Xenopus tropicalis)
Autophosphorylation of PAK (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation and activation of VAV (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of MEK4 by MEKK1 (Xenopus tropicalis)
ADP [cytosol]
Role of LAT2/NTAL/LAB on calcium mobilization (Xenopus tropicalis)
Phosphorylation of PIP2 to PIP3 by PI3K (Xenopus tropicalis)
ADP [cytosol]
Fcgamma receptor (FCGR) dependent phagocytosis (Xenopus tropicalis)
Regulation of actin dynamics for phagocytic cup formation (Xenopus tropicalis)
ABL phosphorylates WAVEs (Xenopus tropicalis)
ADP [cytosol]
Autophosphorylation of PAK1 (Xenopus tropicalis)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Xenopus tropicalis)
Mother filament:ARP2/3:actin:ADP [cytosol] (Xenopus tropicalis)
Actin:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Detachment of WASP/WAVE (Xenopus tropicalis)
Mother filament:ARP2/3:actin:ADP [cytosol] (Xenopus tropicalis)
Actin:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Xenopus tropicalis)
ADP [cytosol]
Transphosphorylation of pLIMK1 (Xenopus tropicalis)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Xenopus tropicalis)
ADP [cytosol]
Role of phospholipids in phagocytosis (Xenopus tropicalis)
DAG stimulates protein kinase C-delta (Xenopus tropicalis)
ADP [cytosol]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways (Xenopus tropicalis)
NOD1/2 Signaling Pathway (Xenopus tropicalis)
Activation of p38 MAPK (Xenopus tropicalis)
ADP [cytosol]
TAK1 phosphorylates MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll-like Receptor Cascades (Xenopus tropicalis)
Toll Like Receptor 10 (TLR10) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 2 (TLR2) Cascade (Xenopus tropicalis)
Toll Like Receptor TLR1:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor TLR6:TLR2 Cascade (Xenopus tropicalis)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 3 (TLR3) Cascade (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 4 (TLR4) Cascade (Xenopus tropicalis)
MyD88-independent TLR4 cascade (Xenopus tropicalis)
TRIF (TICAM1)-mediated TLR4 signaling (Xenopus tropicalis)
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 5 (TLR5) Cascade (Xenopus tropicalis)
MyD88 cascade initiated on plasma membrane (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 7/8 (TLR7/8) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Toll Like Receptor 9 (TLR9) Cascade (Xenopus tropicalis)
MyD88 dependent cascade initiated on endosome (Xenopus tropicalis)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Xenopus tropicalis)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Xenopus tropicalis)
ADP [cytosol]
MAP kinase activation (Xenopus tropicalis)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
ADP [cytosol]
MAP3K8 (TPL2)-dependent MAPK1/3 activation (Xenopus tropicalis)
MAP3K8 is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
activated TAK1 mediates p38 MAPK activation (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
ADP [cytosol]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
ADP [cytosol]
Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins. (Xenopus tropicalis)
Mitochondrial Uncoupling (Xenopus tropicalis)
The proton buffering model (Xenopus tropicalis)
Protons are translocated from the intermembrane space to the matrix (Xenopus tropicalis)
Purine nucleotide [cytosol]
ADP [cytosol]
Biological oxidations (Xenopus tropicalis)
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
Transport and synthesis of PAPS (Xenopus tropicalis)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Xenopus tropicalis)
ADP [cytosol]
Glutathione conjugation (Xenopus tropicalis)
Glutathione synthesis and recycling (Xenopus tropicalis)
GCL ligates L-Glu to L-Cys (Xenopus tropicalis)
ADP [cytosol]
OPLAH hydrolyses OPRO to L-Glu (Xenopus tropicalis)
ADP [cytosol]
Inositol phosphate metabolism (Xenopus tropicalis)
Synthesis of IP3 and IP4 in the cytosol (Xenopus tropicalis)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
Synthesis of pyrophosphates in the cytosol (Xenopus tropicalis)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Xenopus tropicalis)
ADP [cytosol]
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)
ADP [cytosol]
Integration of energy metabolism (Xenopus tropicalis)
Regulation of insulin secretion (Xenopus tropicalis)
KCNJ11 tetramer:ABCC8 tetramer binds 4xATP, closing the channel (Xenopus tropicalis)
Mg2+:ADP [cytosol]
ADP [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Creatine metabolism (Xenopus tropicalis)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Xenopus tropicalis)
ADP [cytosol]
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Xenopus tropicalis)
ADP [cytosol]
Glutamate and glutamine metabolism (Xenopus tropicalis)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Xenopus tropicalis)
ADP [cytosol]
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Xenopus tropicalis)
ADP [cytosol]
Histidine catabolism (Xenopus tropicalis)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Xenopus tropicalis)
ADP [cytosol]
Metabolism of carbohydrates (Xenopus tropicalis)
Formation of xylulose-5-phosphate (Xenopus tropicalis)
XYLB phosphorylates D-xylulose (Xenopus tropicalis)
ADP [cytosol]
Galactose catabolism (Xenopus tropicalis)
GALK1 phosphorylates Gal to Gal1P (Xenopus tropicalis)
ADP [cytosol]
Glucose metabolism (Xenopus tropicalis)
Glycolysis (Xenopus tropicalis)
ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)
ADP [cytosol]
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Xenopus tropicalis)
ADP [cytosol]
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
ADP [cytosol]
Regulation of glycolysis by fructose 2,6-bisphosphate metabolism (Xenopus tropicalis)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Xenopus tropicalis)
ADP [cytosol]
Glycogen metabolism (Xenopus tropicalis)
Glycogen breakdown (glycogenolysis) (Xenopus tropicalis)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Xenopus tropicalis)
ADP [cytosol]
Glycosaminoglycan metabolism (Xenopus tropicalis)
Transport and synthesis of PAPS (Xenopus tropicalis)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Xenopus tropicalis)
ADP [cytosol]
Pentose phosphate pathway (Xenopus tropicalis)
RBKS phosphorylates ribose to R5P (Xenopus tropicalis)
ADP [cytosol]
SHPK phosphorylates Sedo to Sedo7P (Xenopus tropicalis)
ADP [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Carnitine metabolism (Xenopus tropicalis)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
ADP [cytosol]
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
ADP [cytosol]
Fatty acyl-CoA biosynthesis (Xenopus tropicalis)
ACLY tetramer transforms CIT to Ac-CoA (Xenopus tropicalis)
ADP [cytosol]
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Xenopus tropicalis)
ADP [cytosol]
Metabolism of steroids (Xenopus tropicalis)
Bile acid and bile salt metabolism (Xenopus tropicalis)
Recycling of bile acids and salts (Xenopus tropicalis)
ABCC3 transports bile salts from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
Cholesterol biosynthesis (Xenopus tropicalis)
MVD decarboxylates MVA5PP to IPPP (Xenopus tropicalis)
ADP [cytosol]
Phospholipid metabolism (Xenopus tropicalis)
Glycerophospholipid biosynthesis (Xenopus tropicalis)
Synthesis of PC (Xenopus tropicalis)
Cho is phosphorylated to PCho by CHK dimer (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PE (Xenopus tropicalis)
ETA is phosphorylated to PETA by CHK/ETNK (Xenopus tropicalis)
ADP [cytosol]
PI Metabolism (Xenopus tropicalis)
Synthesis of PIPs at the ER membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PIPs at the Golgi membrane (Xenopus tropicalis)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Xenopus tropicalis)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Xenopus tropicalis)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Xenopus tropicalis)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PIPs at the early endosome membrane (Xenopus tropicalis)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Xenopus tropicalis)
ADP [cytosol]
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Xenopus tropicalis)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PIPs at the late endosome membrane (Xenopus tropicalis)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PIPs at the plasma membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
Sphingolipid metabolism (Xenopus tropicalis)
Glycosphingolipid metabolism (Xenopus tropicalis)
Glycosphingolipid biosynthesis (Xenopus tropicalis)
CERK phosphorylates CERA to form C1P (Xenopus tropicalis)
ADP [cytosol]
Sphingolipid de novo biosynthesis (Xenopus tropicalis)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Xenopus tropicalis)
ADP [cytosol]
SPHK2 phosphorylates sphingoid (Xenopus tropicalis)
ADP [cytosol]
Triglyceride metabolism (Xenopus tropicalis)
Triglyceride biosynthesis (Xenopus tropicalis)
Conversion of Glycerol to Glycerol-3-phosphate (Xenopus tropicalis)
ADP [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Xenopus tropicalis)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Xenopus tropicalis)
ADP [cytosol]
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Xenopus tropicalis)
ADP [cytosol]
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Xenopus tropicalis)
ADP [cytosol]
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Xenopus tropicalis)
ADP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Xenopus tropicalis)
ADP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Xenopus tropicalis)
(d)NDPs [cytosol]
ADP [cytosol]
ADP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)
ADP [cytosol]
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Xenopus tropicalis)
ADP [cytosol]
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Xenopus tropicalis)
ADP [cytosol]
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Xenopus tropicalis)
ADP [cytosol]
Nucleotide biosynthesis (Xenopus tropicalis)
Purine ribonucleoside monophosphate biosynthesis (Xenopus tropicalis)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Xenopus tropicalis)
ADP [cytosol]
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Xenopus tropicalis)
ADP [cytosol]
FGAM + ATP => AIR + ADP + Pi (Xenopus tropicalis)
ADP [cytosol]
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Xenopus tropicalis)
ADP [cytosol]
Pyrimidine biosynthesis (Xenopus tropicalis)
CAD hexamer transforms L-Gln to CAP (Xenopus tropicalis)
ADP [cytosol]
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Xenopus tropicalis)
ADP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Xenopus tropicalis)
ADP [cytosol]
Pyrimidine catabolism (Xenopus tropicalis)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A) (Xenopus tropicalis)
ADP [cytosol]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Xenopus tropicalis)
ADP [cytosol]
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Xenopus tropicalis)
ADP [cytosol]
Pyrimidine salvage (Xenopus tropicalis)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Xenopus tropicalis)
ADP [cytosol]
UCKL1 phosphorylates urindine, cytidine (Xenopus tropicalis)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Xenopus tropicalis)
ADP [cytosol]
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Xenopus tropicalis)
ADP [cytosol]
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Xenopus tropicalis)
ADP [cytosol]
Metabolism of porphyrins (Xenopus tropicalis)
Heme biosynthesis (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
Heme degradation (Xenopus tropicalis)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of cofactors (Xenopus tropicalis)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Xenopus tropicalis)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Xenopus tropicalis)
ADP [cytosol]
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Xenopus tropicalis)
ADP [cytosol]
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Xenopus tropicalis)
Transport of RCbl within the body (Xenopus tropicalis)
ABCC1 transports cytosolic RCbl to extracellular region (Xenopus tropicalis)
ADP [cytosol]
Metabolism of folate and pterines (Xenopus tropicalis)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Xenopus tropicalis)
ADP [cytosol]
FPGS-2 transforms THF to THFPG (Xenopus tropicalis)
ADP [cytosol]
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Xenopus tropicalis)
ADP [cytosol]
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Xenopus tropicalis)
ADP [cytosol]
Nicotinate metabolism (Xenopus tropicalis)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)
ADP [cytosol]
Vitamin B2 (riboflavin) metabolism (Xenopus tropicalis)
RFK:Mg2+ phosphorylates RIB (Xenopus tropicalis)
ADP [cytosol]
Vitamin B5 (pantothenate) metabolism (Xenopus tropicalis)
Coenzyme A biosynthesis (Xenopus tropicalis)
COASY phosphorylates DP-CoA (Xenopus tropicalis)
ADP [cytosol]
DCAKD phosphorylates DP-CoA (Xenopus tropicalis)
ADP [cytosol]
PANK2 phosphorylates PanK (Xenopus tropicalis)
ADP [cytosol]
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Xenopus tropicalis)
ADP [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Xenopus tropicalis)
2xPDKX:2xZn2+ phosphorylates PDX (Xenopus tropicalis)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXA (Xenopus tropicalis)
ADP [cytosol]
2xPDXK:2xZn2+ phosphorylates PXL (Xenopus tropicalis)
ADP [cytosol]
Metabolism of RNA (Xenopus tropicalis)
Nonsense-Mediated Decay (NMD) (Xenopus tropicalis)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) (Xenopus tropicalis)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
ADP [cytosol]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
Synthesis of substrates in N-glycan biosythesis (Xenopus tropicalis)
GDP-fucose biosynthesis (Xenopus tropicalis)
FUK phosphorylates beta-Fuc to Fuc1P (Xenopus tropicalis)
ADP [cytosol]
Sialic acid metabolism (Xenopus tropicalis)
GNE phosphorylates ManNAc to ManNAc-6-P (Xenopus tropicalis)
ADP [cytosol]
Synthesis of Dolichyl-phosphate (Xenopus tropicalis)
MVD decarboxylates MVA5PP to IPPP (Xenopus tropicalis)
ADP [cytosol]
Carboxyterminal post-translational modifications of tubulin (Xenopus tropicalis)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Xenopus tropicalis)
ADP [cytosol]
TTLLs polyglutamylate tubulin (Xenopus tropicalis)
ADP [cytosol]
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Xenopus tropicalis)
FN3K phosphorylates ketosamines (Xenopus tropicalis)
ADP [cytosol]
FN3KRP phosphorylates PsiAm, RibAm (Xenopus tropicalis)
ADP [cytosol]
Protein folding (Xenopus tropicalis)
Chaperonin-mediated protein folding (Xenopus tropicalis)
Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding (Xenopus tropicalis)
ATP binds G-protein beta associated TRiC/CCT (Xenopus tropicalis)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
ATP hydrolysis promotes folding of G-protein beta by TRiC/CCT (Xenopus tropicalis)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
PDCL binds G-protein beta and TRiC/CCT (Xenopus tropicalis)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
PDCL promotes G-protein beta 5 folding (Xenopus tropicalis)
GNB5:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded GNB5:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
GNB5:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
PDCL releases folded G-beta from TRiC/CCT (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
p-S18,S19,S20,S25-PDCL:Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
Partially folded G-protein beta 1-4:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
TRiC/CCT binds unfolded G-protein beta subunit (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Unfolded G-protein beta subunit:CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Surfactant metabolism (Xenopus tropicalis)
ABCA3 transports PC, PG from ER membrane to lamellar body (Xenopus tropicalis)
ADP [cytosol]
Translation (Xenopus tropicalis)
Eukaryotic Translation Initiation (Xenopus tropicalis)
Cap-dependent Translation Initiation (Xenopus tropicalis)
Ribosomal scanning and start codon recognition (Xenopus tropicalis)
Ribosomal scanning (Xenopus tropicalis)
ADP [cytosol]
Muscle contraction (Xenopus tropicalis)
Cardiac conduction (Xenopus tropicalis)
Ion homeostasis (Xenopus tropicalis)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Xenopus tropicalis)
ADP [cytosol]
PRKACA phosphorylates PLN (Xenopus tropicalis)
ADP [cytosol]
PRKACA phosphorylates TNNI3 (Xenopus tropicalis)
ADP [cytosol]
Neuronal System (Xenopus tropicalis)
Transmission across Chemical Synapses (Xenopus tropicalis)
Neurotransmitter uptake and metabolism In glial cells (Xenopus tropicalis)
Astrocytic Glutamate-Glutamine Uptake And Metabolism (Xenopus tropicalis)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Xenopus tropicalis)
ADP [cytosol]
Programmed Cell Death (Xenopus tropicalis)
Apoptosis (Xenopus tropicalis)
Intrinsic Pathway for Apoptosis (Xenopus tropicalis)
Apoptotic factor-mediated response (Xenopus tropicalis)
Cytochrome c-mediated apoptotic response (Xenopus tropicalis)
Activation of caspases through apoptosome-mediated cleavage (Xenopus tropicalis)
Cleavage of Procaspase-3 by the apoptosome (Xenopus tropicalis)
ADP [cytosol]
Cleavage of Procaspase-7 by the apoptosome (Xenopus tropicalis)
ADP [cytosol]
Formation of apoptosome (Xenopus tropicalis)
CYCS binds to APAF1 (Xenopus tropicalis)
ADP [cytosol]
APAF1:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Cleavage of Procaspase‑9 to caspase‑9 (Xenopus tropicalis)
ADP [cytosol]
Regulation of the apoptosome activity (Xenopus tropicalis)
APAF1 binds AVEN (Xenopus tropicalis)
APAF1:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
APAF1:AVEN [cytosol] (Xenopus tropicalis)
APAF1:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
CASP9 is phosphorylated at T412 (Xenopus tropicalis)
ADP [cytosol]
Sensory Perception (Xenopus tropicalis)
Visual phototransduction (Xenopus tropicalis)
The canonical retinoid cycle in rods (twilight vision) (Xenopus tropicalis)
ABCA4 mediates atRAL transport (Xenopus tropicalis)
ADP [cytosol]
Signal Transduction (Xenopus tropicalis)
Death Receptor Signaling (Xenopus tropicalis)
TNF signaling (Xenopus tropicalis)
Regulation of TNFR1 signaling (Xenopus tropicalis)
ULK1 phosphorylates RIPK1 at S357 (Xenopus tropicalis)
ADP [cytosol]
Intracellular signaling by second messengers (Xenopus tropicalis)
DAG and IP3 signaling (Xenopus tropicalis)
CaM pathway (Xenopus tropicalis)
Calmodulin induced events (Xenopus tropicalis)
PKC phosphorylates GRK2 (Xenopus tropicalis)
ADP [cytosol]
DAG stimulates protein kinase C-delta (Xenopus tropicalis)
ADP [cytosol]
PIP3 activates AKT signaling (Xenopus tropicalis)
Negative regulation of the PI3K/AKT network (Xenopus tropicalis)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
PTEN Regulation (Xenopus tropicalis)
Regulation of PTEN stability and activity (Xenopus tropicalis)
FRK phosphorylates PTEN (Xenopus tropicalis)
ADP [cytosol]
MAPK family signaling cascades (Xenopus tropicalis)
MAPK1/MAPK3 signaling (Xenopus tropicalis)
RAF/MAP kinase cascade (Xenopus tropicalis)
Negative regulation of MAPK pathway (Xenopus tropicalis)
MAPK12 phosphorylates PTPN3 (Xenopus tropicalis)
ADP [cytosol]
Negative feedback regulation of MAPK pathway (Xenopus tropicalis)
Activated MAPK phosphorylates RAF1 (Xenopus tropicalis)
ADP [cytosol]
MAPK6/MAPK4 signaling (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
ADP [cytosol]
PAK1,2,3 phosphorylates MAPK6,4 (Xenopus tropicalis)
ADP [cytosol]
MTOR signalling (Xenopus tropicalis)
mTORC1 phosphorylates AKT1S1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Erythropoietin (Xenopus tropicalis)
Erythropoietin activates Phosphoinositide-3-kinase (PI3K) (Xenopus tropicalis)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Xenopus tropicalis)
ADP [cytosol]
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Opioid Signalling (Xenopus tropicalis)
DARPP-32 events (Xenopus tropicalis)
PKA phosphorylates DARPP-32 on Thr34 (Xenopus tropicalis)
ADP [cytosol]
PKA phosphorylates PDE4B (Xenopus tropicalis)
ADP [cytosol]
G-protein mediated events (Xenopus tropicalis)
PLC beta mediated events (Xenopus tropicalis)
Ca-dependent events (Xenopus tropicalis)
CaM pathway (Xenopus tropicalis)
Calmodulin induced events (Xenopus tropicalis)
PKC phosphorylates GRK2 (Xenopus tropicalis)
ADP [cytosol]
phospho-PLA2 pathway (Xenopus tropicalis)
Phosphorylation of cPLA2 by ERK-2 (Xenopus tropicalis)
ADP [cytosol]
G alpha (q) signalling events (Xenopus tropicalis)
Effects of PIP2 hydrolysis (Xenopus tropicalis)
DAG kinase produces phosphatidic acid from DAG (Xenopus tropicalis)
ADP [cytosol]
G alpha (s) signalling events (Xenopus tropicalis)
ADRB2 in ADRB2:GRK complex is phosphorylated (Xenopus tropicalis)
ADP [cytosol]
G-protein beta:gamma signalling (Xenopus tropicalis)
G beta:gamma signalling through PI3Kgamma (Xenopus tropicalis)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Hedgehog (Xenopus tropicalis)
Hedgehog 'off' state (Xenopus tropicalis)
GLI3 is processed to GLI3R by the proteasome (Xenopus tropicalis)
PKA phosphorylates GLI3 (Xenopus tropicalis)
ADP [cytosol]
Hedgehog ligand biogenesis (Xenopus tropicalis)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Xenopus tropicalis)
ADP [cytosol]
Signaling by Hippo (Xenopus tropicalis)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of WWTR1 (TAZ) by LATS1 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of YAP by LATS1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by NOTCH (Xenopus tropicalis)
Signaling by NOTCH3 (Xenopus tropicalis)
NOTCH3 Activation and Transmission of Signal to the Nucleus (Xenopus tropicalis)
EGFR phosphorylates NOTCH3 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Non-Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by PTK6 (Xenopus tropicalis)
PTK6 Regulates Cell Cycle (Xenopus tropicalis)
PTK6 phosphorylates CDKN1B (Xenopus tropicalis)
ADP [cytosol]
PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases (Xenopus tropicalis)
PTK6 phosphorylates ARHGAP35 (Xenopus tropicalis)
ADP [cytosol]
PTK6 phosphorylates BCAR1 (Xenopus tropicalis)
ADP [cytosol]
PTK6 promotes HIF1A stabilization (Xenopus tropicalis)
EGFR phosphorylates GPNMB (Xenopus tropicalis)
ADP [cytosol]
LINC01139 facilitates PTK6 autophosphorylation (Xenopus tropicalis)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Xenopus tropicalis)
ADP [cytosol]
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by ALK (Xenopus tropicalis)
PI3K synthesizes PIP3 downstream of ALK (Xenopus tropicalis)
ADP [cytosol]
Signaling by EGFR (Xenopus tropicalis)
EGFR autophosphorylation (Xenopus tropicalis)
ADP [cytosol]
EGFR downregulation (Xenopus tropicalis)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Xenopus tropicalis)
ADP [cytosol]
EGFR interacts with phospholipase C-gamma (Xenopus tropicalis)
EGFR activates PLC-gamma1 by phosphorylation (Xenopus tropicalis)
ADP [cytosol]
GAB1 signalosome (Xenopus tropicalis)
GAB1 phosphorylation by EGFR kinase (Xenopus tropicalis)
ADP [cytosol]
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Xenopus tropicalis)
ADP [cytosol]
SHC1 events in EGFR signaling (Xenopus tropicalis)
SHC1 phosphorylation by phosphorylated EGFR (Xenopus tropicalis)
ADP [cytosol]
Signaling by ERBB2 (Xenopus tropicalis)
PI3K events in ERBB2 signaling (Xenopus tropicalis)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Xenopus tropicalis)
ADP [cytosol]
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Xenopus tropicalis)
ADP [cytosol]
SHC1 events in ERBB2 signaling (Xenopus tropicalis)
SHC1 phosphorylation by ERBB2 heterodimers (Xenopus tropicalis)
ADP [cytosol]
Signaling by ERBB4 (Xenopus tropicalis)
PI3K events in ERBB4 signaling (Xenopus tropicalis)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Xenopus tropicalis)
ADP [cytosol]
SHC1 events in ERBB4 signaling (Xenopus tropicalis)
Phosphorylation of SHC1 by ERBB4 homodimers (Xenopus tropicalis)
ADP [cytosol]
Trans-autophosphorylation of ERBB4 homodimers (Xenopus tropicalis)
ADP [cytosol]
Signaling by FGFR (Xenopus tropicalis)
Signaling by FGFR1 (Xenopus tropicalis)
Downstream signaling of activated FGFR1 (Xenopus tropicalis)
FRS-mediated FGFR1 signaling (Xenopus tropicalis)
Activated FGFR1 phosphorylates FRS2 (Xenopus tropicalis)
ADP [cytosol]
Activated FGFR1 phosphorylates FRS3 (Xenopus tropicalis)
ADP [cytosol]
Activated FGFR1:p-FRS phosphorylates PPTN11 (Xenopus tropicalis)
ADP [cytosol]
PI-3K cascade:FGFR1 (Xenopus tropicalis)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Phospholipase C-mediated cascade: FGFR1 (Xenopus tropicalis)
Activated FGFR1 phosphorylates PLCG1 (Xenopus tropicalis)
ADP [cytosol]
SHC-mediated cascade:FGFR1 (Xenopus tropicalis)
Activated FGFR1 phosphorylates SHC1 (Xenopus tropicalis)
ADP [cytosol]
FGFR1 ligand binding and activation (Xenopus tropicalis)
FGFR1b ligand binding and activation (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR1b (Xenopus tropicalis)
ADP [cytosol]
FGFR1c and Klotho ligand binding and activation (Xenopus tropicalis)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Xenopus tropicalis)
ADP [cytosol]
FGFR1c ligand binding and activation (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR1c (Xenopus tropicalis)
ADP [cytosol]
Negative regulation of FGFR1 signaling (Xenopus tropicalis)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Xenopus tropicalis)
ADP [cytosol]
Spry regulation of FGF signaling (Xenopus tropicalis)
SPRY2 is phosphorylated by phosphorylated MNK1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by FGFR2 (Xenopus tropicalis)
Downstream signaling of activated FGFR2 (Xenopus tropicalis)
FRS-mediated FGFR2 signaling (Xenopus tropicalis)
Activated FGFR2 phosphorylates PPTN11 (Xenopus tropicalis)
ADP [cytosol]
PI-3K cascade:FGFR2 (Xenopus tropicalis)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Negative regulation of FGFR2 signaling (Xenopus tropicalis)
Spry regulation of FGF signaling (Xenopus tropicalis)
SPRY2 is phosphorylated by phosphorylated MNK1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by FGFR3 (Xenopus tropicalis)
Downstream signaling of activated FGFR3 (Xenopus tropicalis)
FRS-mediated FGFR3 signaling (Xenopus tropicalis)
Activated FGFR3 phosphorylates PPTN11 (Xenopus tropicalis)
ADP [cytosol]
PI-3K cascade:FGFR3 (Xenopus tropicalis)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Negative regulation of FGFR3 signaling (Xenopus tropicalis)
Spry regulation of FGF signaling (Xenopus tropicalis)
SPRY2 is phosphorylated by phosphorylated MNK1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by FGFR4 (Xenopus tropicalis)
Downstream signaling of activated FGFR4 (Xenopus tropicalis)
FRS-mediated FGFR4 signaling (Xenopus tropicalis)
Activated FGFR4 phosphorylates FRS2 (Xenopus tropicalis)
ADP [cytosol]
Activated FGFR4 phosphorylates FRS3 (Xenopus tropicalis)
ADP [cytosol]
Activated FGFR4 phosphorylates PPTN11 (Xenopus tropicalis)
ADP [cytosol]
PI-3K cascade:FGFR4 (Xenopus tropicalis)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Phospholipase C-mediated cascade; FGFR4 (Xenopus tropicalis)
Activated FGFR4 phosphorylates PLCG1 (Xenopus tropicalis)
ADP [cytosol]
SHC-mediated cascade:FGFR4 (Xenopus tropicalis)
Activated FGFR4 phosphorylates SHC1 (Xenopus tropicalis)
ADP [cytosol]
FGFR4 ligand binding and activation (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR4 (Xenopus tropicalis)
ADP [cytosol]
betaKlotho-mediated ligand binding (Xenopus tropicalis)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Xenopus tropicalis)
ADP [cytosol]
Negative regulation of FGFR4 signaling (Xenopus tropicalis)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Xenopus tropicalis)
ADP [cytosol]
Spry regulation of FGF signaling (Xenopus tropicalis)
SPRY2 is phosphorylated by phosphorylated MNK1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by Insulin receptor (Xenopus tropicalis)
Autophosphorylation of insulin receptor (Xenopus tropicalis)
ADP [cytosol]
Insulin receptor signalling cascade (Xenopus tropicalis)
IRS activation (Xenopus tropicalis)
Phosphorylation of IRS (Xenopus tropicalis)
ADP [cytosol]
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of SHC1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by LTK (Xenopus tropicalis)
Active LTK phosphorylates IRS1 (Xenopus tropicalis)
ADP [cytosol]
Active LTK receptor phosphorylates SHC1 (Xenopus tropicalis)
ADP [cytosol]
Autophosphorylation of LTK dimer:ALKAL1,2 (Xenopus tropicalis)
ADP [cytosol]
Signaling by MET (Xenopus tropicalis)
MET Receptor Activation (Xenopus tropicalis)
MET dimers autophosphorylate (Xenopus tropicalis)
ADP [cytosol]
MET activates PI3K/AKT signaling (Xenopus tropicalis)
MET bound PI3K generates PIP3 (Xenopus tropicalis)
ADP [cytosol]
MET phosphorylates GAB1 (Xenopus tropicalis)
ADP [cytosol]
MET activates RAS signaling (Xenopus tropicalis)
MET phosphorylates SHC1-2 (Xenopus tropicalis)
ADP [cytosol]
MET activates STAT3 (Xenopus tropicalis)
MET phosphorylates STAT3 (Xenopus tropicalis)
ADP [cytosol]
Negative regulation of MET activity (Xenopus tropicalis)
MET phosphorylates CBL (Xenopus tropicalis)
ADP [cytosol]
Signaling by MST1 (Xenopus tropicalis)
MST1R autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
Signaling by NTRKs (Xenopus tropicalis)
Signaling by NTRK1 (TRKA) (Xenopus tropicalis)
PI3K/AKT activation (Xenopus tropicalis)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
ADP [cytosol]
Signalling to ERKs (Xenopus tropicalis)
Prolonged ERK activation events (Xenopus tropicalis)
ARMS-mediated activation (Xenopus tropicalis)
ARMS is phosphorylated by active TrkA receptor (Xenopus tropicalis)
ADP [cytosol]
Frs2-mediated activation (Xenopus tropicalis)
FRS2 is phosphorylated by active TrkA receptor (Xenopus tropicalis)
ADP [cytosol]
Signaling by PDGF (Xenopus tropicalis)
Autophosphorylation of PDGF alpha/beta receptors (Xenopus tropicalis)
ADP [cytosol]
Autophosphorylation of PDGF beta receptors (Xenopus tropicalis)
ADP [cytosol]
Downstream signal transduction (Xenopus tropicalis)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of PLCgamma by PDGFR (Xenopus tropicalis)
ADP [cytosol]
Signaling by SCF-KIT (Xenopus tropicalis)
Autophosphorylation of KIT (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation and activation of VAV1 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of GAB2 by SFKs (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of JAK2 (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of SHP2 by SFKs (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of STATs (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of p-KIT on Y900 by Src kinases (Xenopus tropicalis)
ADP [cytosol]
Regulation of KIT signaling (Xenopus tropicalis)
Phosphorylation of APS (Xenopus tropicalis)
ADP [cytosol]
Synthesis of PIP3 from PIP2 by PI3K (Xenopus tropicalis)
ADP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Xenopus tropicalis)
IGF1,2:IGF1R autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
IGF1R signaling cascade (Xenopus tropicalis)
IRS-related events triggered by IGF1R (Xenopus tropicalis)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Xenopus tropicalis)
ADP [cytosol]
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
SHC-related events triggered by IGF1R (Xenopus tropicalis)
IGF1R phosphorylates SHC1 (Xenopus tropicalis)
ADP [cytosol]
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
FYN autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
FYN phosphorylates PAK2 (Xenopus tropicalis)
ADP [cytosol]
PAK2 autophorylates (Xenopus tropicalis)
ADP [cytosol]
PTK2 autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
ADP [cytosol]
VEGFR2 autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
VEGFR2 mediated cell proliferation (Xenopus tropicalis)
PDK1 phosphorylates PKC (Xenopus tropicalis)
ADP [cytosol]
PKC autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
VEGFR2 mediated vascular permeability (Xenopus tropicalis)
PAK1-3 autophosphorylates (Xenopus tropicalis)
ADP [cytosol]
PAK1-3 phosphorylates VE-cadherin (Xenopus tropicalis)
ADP [cytosol]
p-Y420-FYN is phosphorylated on S21 (Xenopus tropicalis)
ADP [cytosol]
p38 MAPK activation by VEGFR (Xenopus tropicalis)
ADP [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases Activate NADPH Oxidases (Xenopus tropicalis)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Xenopus tropicalis)
ADP [cytosol]
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Xenopus tropicalis)
ADP [cytosol]
PKC phosphorylates NCF1 (Xenopus tropicalis)
ADP [cytosol]
RHO GTPases Activate WASPs and WAVEs (Xenopus tropicalis)
ABL phosphorylates WAVEs (Xenopus tropicalis)
ADP [cytosol]
Branching and elongation of mother and daughter filaments (Xenopus tropicalis)
Mother filament:ARP2/3:actin:ADP [cytosol] (Xenopus tropicalis)
Actin:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
Detachment of WASP/WAVE (Xenopus tropicalis)
Mother filament:ARP2/3:actin:ADP [cytosol] (Xenopus tropicalis)
Actin:ADP [cytosol] (Xenopus tropicalis)
ADP [cytosol]
p-ERK phosphorylates WAVEs and ABI (Xenopus tropicalis)
ADP [cytosol]
RHO GTPases activate PAKs (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
ADP [cytosol]
PAK1 phosphorylates FLNA (Xenopus tropicalis)
ADP [cytosol]
PAK1 phosphorylates LIMK1 (Xenopus tropicalis)
ADP [cytosol]
PAK1 phosphorylates myosin phosphatase (Xenopus tropicalis)
ADP [cytosol]
RHO GTPases activate PKNs (Xenopus tropicalis)
PDPK1 phosphorylates PKN1,2,3 (Xenopus tropicalis)
ADP [cytosol]
Signaling by TGFB family members (Xenopus tropicalis)
Signaling by Activin (Xenopus tropicalis)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Xenopus tropicalis)
ADP [cytosol]
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Xenopus tropicalis)
ADP [cytosol]
Signaling by BMP (Xenopus tropicalis)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Xenopus tropicalis)
ADP [cytosol]
Type II receptor phosphorylates type I receptor (Xenopus tropicalis)
ADP [cytosol]
Signaling by TGF-beta Receptor Complex (Xenopus tropicalis)
Transcriptional activity of SMAD2/SMAD3:SMAD4 heterotrimer (Xenopus tropicalis)
Downregulation of SMAD2/3:SMAD4 transcriptional activity (Xenopus tropicalis)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Xenopus tropicalis)
ADP [cytosol]
Signaling by WNT (Xenopus tropicalis)
Beta-catenin independent WNT signaling (Xenopus tropicalis)
Ca2+ pathway (Xenopus tropicalis)
Activation of NLK (Xenopus tropicalis)
ADP [cytosol]
PCP/CE pathway (Xenopus tropicalis)
WNT5A-dependent internalization of FZD4 (Xenopus tropicalis)
DVL2 is phosphorylated by PKC (Xenopus tropicalis)
ADP [cytosol]
TCF dependent signaling in response to WNT (Xenopus tropicalis)
WNT mediated activation of DVL (Xenopus tropicalis)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Xenopus tropicalis)
ADP [cytosol]
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
ABC transporters in lipid homeostasis (Xenopus tropicalis)
ABCA3 transports PC, PG from ER membrane to lamellar body (Xenopus tropicalis)
ADP [cytosol]
ABCA5 transports CHOL from lysosomal lumen to cytosol (Xenopus tropicalis)
ADP [cytosol]
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Xenopus tropicalis)
ADP [cytosol]
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
ADP [cytosol]
ABCG4 may mediate cholesterol efflux (Xenopus tropicalis)
ADP [cytosol]
ABCA4 mediates atRAL transport (Xenopus tropicalis)
ADP [cytosol]
CFTR transports Cl- from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
HCO3- transport through ion channel (Xenopus tropicalis)
ADP [cytosol]
Mitochondrial ABC transporters (Xenopus tropicalis)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Xenopus tropicalis)
ADP [cytosol]
The ABCC family mediates organic anion transport (Xenopus tropicalis)
ADP [cytosol]
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Xenopus tropicalis)
ADP [cytosol]
Aquaporin-mediated transport (Xenopus tropicalis)
Vasopressin regulates renal water homeostasis via Aquaporins (Xenopus tropicalis)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Xenopus tropicalis)
ADP [cytosol]
Ion channel transport (Xenopus tropicalis)
Ion transport by P-type ATPases (Xenopus tropicalis)
ATP12A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)
ADP [cytosol]
ATP13A1 transports Mn2+ from cytosol to ER lumen (Xenopus tropicalis)
ADP [cytosol]
ATP13A2 transports cations from cytosol to lysosomal lumen (Xenopus tropicalis)
ADP [cytosol]
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Xenopus tropicalis)
ADP [cytosol]
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Xenopus tropicalis)
ADP [cytosol]
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Xenopus tropicalis)
ADP [cytosol]
ATP4A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)
ADP [cytosol]
ATP7A transports cytosolic Cu2+ to extracellular region (Xenopus tropicalis)
ADP [cytosol]
ATP7B transports cytosolic Cu2+ to Golgi lumen (Xenopus tropicalis)
ADP [cytosol]
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Xenopus tropicalis)
ADP [cytosol]
Iron uptake and transport (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
ADP [cytosol]
Transferrin endocytosis and recycling (Xenopus tropicalis)
Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
ADP [cytosol]
Plasma lipoprotein assembly, remodeling, and clearance (Xenopus tropicalis)
Plasma lipoprotein assembly (Xenopus tropicalis)
HDL assembly (Xenopus tropicalis)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Xenopus tropicalis)
ADP [cytosol]
Plasma lipoprotein remodeling (Xenopus tropicalis)
HDL remodeling (Xenopus tropicalis)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
ADP [cytosol]
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of vitamins, nucleosides, and related molecules (Xenopus tropicalis)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Xenopus tropicalis)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
ADP [cytosol]
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
ADP [cytosol]
Vesicle-mediated transport (Xenopus tropicalis)
Membrane Trafficking (Xenopus tropicalis)
Clathrin-mediated endocytosis (Xenopus tropicalis)
Cargo recognition for clathrin-mediated endocytosis (Xenopus tropicalis)
ADBRK1,2 phosphorylate AVPR2 (Xenopus tropicalis)
ADP [cytosol]
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Xenopus tropicalis)
ADP [cytosol]
Endosomal Sorting Complex Required For Transport (ESCRT) (Xenopus tropicalis)
ESCRT Disassembly (Xenopus tropicalis)
ADP [cytosol]
External Reference Information
External Reference
ADP(3-) [ChEBI:456216]
Participates
as a component of
RHOBTB3:ADP [trans-Golgi network membrane] (Bos taurus)
RHOBTB3:ADP [trans-Golgi network membrane] (Mus musculus)
RHOBTB3:ADP [trans-Golgi network membrane] (Caenorhabditis elegans)
RHOBTB3:ADP [trans-Golgi network membrane] (Gallus gallus)
RHOBTB3:ADP [trans-Golgi network membrane] (Drosophila melanogaster)
RHOBTB3:ADP [trans-Golgi network membrane] (Rattus norvegicus)
RHOBTB3:ADP [trans-Golgi network membrane] (Canis familiaris)
RHOBTB3:ADP [trans-Golgi network membrane] (Dictyostelium discoideum)
RHOBTB3:ADP [trans-Golgi network membrane] (Homo sapiens)
GET3:ADP [cytosol] (Saccharomyces cerevisiae)
GET3:ADP [cytosol] (Saccharomyces cerevisiae)
ASNA1:ADP [cytosol] (Homo sapiens)
ADP Bound Myosin Complex [cytosol] (Bos taurus)
ADP Bound Myosin Complex [cytosol] (Mus musculus)
ADP Bound Myosin Complex [cytosol] (Gallus gallus)
ADP Bound Myosin Complex [cytosol] (Canis familiaris)
ADP Bound Myosin Complex [cytosol] (Sus scrofa)
ADP Bound Myosin Complex [cytosol] (Rattus norvegicus)
ADP Bound Myosin Complex [cytosol] (Homo sapiens)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Bos taurus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Gallus gallus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Rattus norvegicus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Sus scrofa)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Caenorhabditis elegans)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Canis familiaris)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Drosophila melanogaster)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Mus musculus)
ADP Bound Smooth Muscle Myosin Complex [cytosol] (Homo sapiens)
CCT/TriC(ADP) [cytosol] (Oryctolagus cuniculus)
Mg2+:ADP [cytosol]
CHL1:Hsc70 [plasma membrane] (Mus musculus)
CHL1:HSP7C [plasma membrane] (Homo sapiens)
p-3S,T844-IRE1 dimer:ADP (yeast) [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Xenopus tropicalis)
HSP40:HSP70:ADP:nascent protein [cytosol] (Sus scrofa)
HSP40:HSP70:ADP:nascent protein [cytosol] (Rattus norvegicus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Saccharomyces cerevisiae)
HSP40:HSP70:ADP:nascent protein [cytosol] (Drosophila melanogaster)
HSP40:HSP70:ADP:nascent protein [cytosol] (Dictyostelium discoideum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Danio rerio)
HSP40:HSP70:ADP:nascent protein [cytosol] (Plasmodium falciparum)
HSP40:HSP70:ADP:nascent protein [cytosol] (Mus musculus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Caenorhabditis elegans)
HSP40:HSP70:ADP:nascent protein [cytosol] (Canis familiaris)
HSP40:HSP70:ADP:nascent protein [cytosol] (Bos taurus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Gallus gallus)
HSP40:HSP70:ADP:nascent protein [cytosol] (Schizosaccharomyces pombe)
HSP40:HSP70:ADP:nascent protein [cytosol] (Homo sapiens)
HSP70:ADP [cytosol] (Dictyostelium discoideum)
HSP70:ADP [cytosol] (Sus scrofa)
HSP70:ADP [cytosol] (Caenorhabditis elegans)
HSP70:ADP [cytosol] (Bos taurus)
HSP70:ADP [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Rattus norvegicus)
HSP70:ADP [cytosol] (Mus musculus)
HSP70:ADP [cytosol] (Xenopus tropicalis)
HSP70:ADP [cytosol] (Saccharomyces cerevisiae)
HSP70:ADP [cytosol] (Danio rerio)
HSP70:ADP [cytosol] (Schizosaccharomyces pombe)
HSP70:ADP [cytosol] (Drosophila melanogaster)
HSP70:ADP [cytosol] (Plasmodium falciparum)
HSP70:ADP [cytosol] (Homo sapiens)
HSPA1B:ADP [cytosol] (Xenopus tropicalis)
HSPA1B:ADP [cytosol] (Homo sapiens)
HSPA1A:ADP [cytosol] (Plasmodium falciparum)
HSPA1A:ADP [cytosol] (Xenopus tropicalis)
HSPA1A:ADP [cytosol] (Sus scrofa)
HSPA1A:ADP [cytosol] (Canis familiaris)
HSPA1A:ADP [cytosol] (Dictyostelium discoideum)
HSPA1A:ADP [cytosol] (Danio rerio)
HSPA1A:ADP [cytosol] (Rattus norvegicus)
HSPA1A:ADP [cytosol] (Mus musculus)
HSPA1A:ADP [cytosol] (Bos taurus)
HSPA1A:ADP [cytosol] (Caenorhabditis elegans)
HSPA1A:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA1A:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA1A:ADP [cytosol] (Homo sapiens)
HSP14:ADP [cytosol] (Schizosaccharomyces pombe)
HSP14:ADP [cytosol] (Plasmodium falciparum)
HSP14:ADP [cytosol] (Xenopus tropicalis)
HSP14:ADP [cytosol] (Dictyostelium discoideum)
HSP14:ADP [cytosol] (Sus scrofa)
HSP14:ADP [cytosol] (Danio rerio)
HSP14:ADP [cytosol] (Canis familiaris)
HSP14:ADP [cytosol] (Rattus norvegicus)
HSP14:ADP [cytosol] (Mus musculus)
HSP14:ADP [cytosol] (Bos taurus)
HSP14:ADP [cytosol] (Saccharomyces cerevisiae)
HSP14:ADP [cytosol] (Homo sapiens)
HSP13:ADP [cytosol] (Plasmodium falciparum)
HSP13:ADP [cytosol] (Sus scrofa)
HSP13:ADP [cytosol] (Danio rerio)
HSP13:ADP [cytosol] (Bos taurus)
HSP13:ADP [cytosol] (Canis familiaris)
HSP13:ADP [cytosol] (Xenopus tropicalis)
HSP13:ADP [cytosol] (Dictyostelium discoideum)
HSP13:ADP [cytosol] (Mus musculus)
HSP13:ADP [cytosol] (Saccharomyces cerevisiae)
HSP13:ADP [cytosol] (Schizosaccharomyces pombe)
HSP13:ADP [cytosol] (Caenorhabditis elegans)
HSP13:ADP [cytosol] (Rattus norvegicus)
HSP13:ADP [cytosol] (Homo sapiens)
HSPA5:ADP [cytosol] (Sus scrofa)
HSPA5:ADP [cytosol] (Danio rerio)
HSPA5:ADP [cytosol] (Caenorhabditis elegans)
HSPA5:ADP [cytosol] (Bos taurus)
HSPA5:ADP [cytosol] (Rattus norvegicus)
HSPA5:ADP [cytosol] (Dictyostelium discoideum)
HSPA5:ADP [cytosol] (Mus musculus)
HSPA5:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA5:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA5:ADP [cytosol] (Canis familiaris)
HSPA5:ADP [cytosol] (Plasmodium falciparum)
HSPA5:ADP [cytosol] (Xenopus tropicalis)
HSPA5:ADP [cytosol] (Homo sapiens)
HSPA2:ADP [cytosol] (Mus musculus)
HSPA2:ADP [cytosol] (Caenorhabditis elegans)
HSPA2:ADP [cytosol] (Bos taurus)
HSPA2:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA2:ADP [cytosol] (Xenopus tropicalis)
HSPA2:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA2:ADP [cytosol] (Canis familiaris)
HSPA2:ADP [cytosol] (Plasmodium falciparum)
HSPA2:ADP [cytosol] (Rattus norvegicus)
HSPA2:ADP [cytosol] (Dictyostelium discoideum)
HSPA2:ADP [cytosol] (Danio rerio)
HSPA2:ADP [cytosol] (Homo sapiens)
HSPA4:ADP [cytosol] (Caenorhabditis elegans)
HSPA4:ADP [cytosol] (Danio rerio)
HSPA4:ADP [cytosol] (Bos taurus)
HSPA4:ADP [cytosol] (Canis familiaris)
HSPA4:ADP [cytosol] (Xenopus tropicalis)
HSPA4:ADP [cytosol] (Dictyostelium discoideum)
HSPA4:ADP [cytosol] (Mus musculus)
HSPA4:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA4:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA4:ADP [cytosol] (Rattus norvegicus)
HSPA4:ADP [cytosol] (Plasmodium falciparum)
HSPA4:ADP [cytosol] (Sus scrofa)
HSPA4:ADP [cytosol] (Homo sapiens)
HSPA9:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA9:ADP [cytosol] (Rattus norvegicus)
HSPA9:ADP [cytosol] (Plasmodium falciparum)
HSPA9:ADP [cytosol] (Sus scrofa)
HSPA9:ADP [cytosol] (Dictyostelium discoideum)
HSPA9:ADP [cytosol] (Danio rerio)
HSPA9:ADP [cytosol] (Canis familiaris)
HSPA9:ADP [cytosol] (Xenopus tropicalis)
HSPA9:ADP [cytosol] (Mus musculus)
HSPA9:ADP [cytosol] (Caenorhabditis elegans)
HSPA9:ADP [cytosol] (Bos taurus)
HSPA9:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA9:ADP [cytosol] (Homo sapiens)
HSPA7:ADP [cytosol] (Homo sapiens)
HSPA4L:ADP [cytosol] (Dictyostelium discoideum)
HSPA4L:ADP [cytosol] (Canis familiaris)
HSPA4L:ADP [cytosol] (Mus musculus)
HSPA4L:ADP [cytosol] (Caenorhabditis elegans)
HSPA4L:ADP [cytosol] (Bos taurus)
HSPA4L:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA4L:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA4L:ADP [cytosol] (Plasmodium falciparum)
HSPA4L:ADP [cytosol] (Sus scrofa)
HSPA4L:ADP [cytosol] (Homo sapiens)
HSPA1L:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA1L:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA1L:ADP [cytosol] (Canis familiaris)
HSPA1L:ADP [cytosol] (Xenopus tropicalis)
HSPA1L:ADP [cytosol] (Plasmodium falciparum)
HSPA1L:ADP [cytosol] (Rattus norvegicus)
HSPA1L:ADP [cytosol] (Sus scrofa)
HSPA1L:ADP [cytosol] (Caenorhabditis elegans)
HSPA1L:ADP [cytosol] (Danio rerio)
HSPA1L:ADP [cytosol] (Bos taurus)
HSPA1L:ADP [cytosol] (Dictyostelium discoideum)
HSPA1L:ADP [cytosol] (Mus musculus)
HSPA1L:ADP [cytosol] (Homo sapiens)
HSPA12A:ADP [cytosol] (Rattus norvegicus)
HSPA12A:ADP [cytosol] (Sus scrofa)
HSPA12A:ADP [cytosol] (Bos taurus)
HSPA12A:ADP [cytosol] (Mus musculus)
HSPA12A:ADP [cytosol] (Canis familiaris)
HSPA12A:ADP [cytosol] (Xenopus tropicalis)
HSPA12A:ADP [cytosol] (Homo sapiens)
HSPA8:ADP [cytosol] (Plasmodium falciparum)
HSPA8:ADP [cytosol] (Rattus norvegicus)
HSPA8:ADP [cytosol] (Danio rerio)
HSPA8:ADP [cytosol] (Caenorhabditis elegans)
HSPA8:ADP [cytosol] (Dictyostelium discoideum)
HSPA8:ADP [cytosol] (Xenopus tropicalis)
HSPA8:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA8:ADP [cytosol] (Drosophila melanogaster)
HSPA8:ADP [cytosol] (Sus scrofa)
HSPA8:ADP [cytosol] (Bos taurus)
HSPA8:ADP [cytosol] (Mus musculus)
HSPA8:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA8:ADP [cytosol] (Canis familiaris)
HSP70:ADP [cytosol] (Gallus gallus)
HSPA8:ADP [cytosol] (Homo sapiens)
HSPA12B:ADP [cytosol] (Rattus norvegicus)
HSPA12B:ADP [cytosol] (Sus scrofa)
HSPA12B:ADP [cytosol] (Danio rerio)
HSPA12B:ADP [cytosol] (Mus musculus)
HSPA12B:ADP [cytosol] (Bos taurus)
HSPA12B:ADP [cytosol] (Xenopus tropicalis)
HSPA12B:ADP [cytosol] (Canis familiaris)
HSPA12B:ADP [cytosol] (Homo sapiens)
HSPA6:ADP [cytosol] (Plasmodium falciparum)
HSPA6:ADP [cytosol] (Sus scrofa)
HSPA6:ADP [cytosol] (Dictyostelium discoideum)
HSPA6:ADP [cytosol] (Danio rerio)
HSPA6:ADP [cytosol] (Caenorhabditis elegans)
HSPA6:ADP [cytosol] (Bos taurus)
HSPA6:ADP [cytosol] (Saccharomyces cerevisiae)
HSPA6:ADP [cytosol] (Schizosaccharomyces pombe)
HSPA6:ADP [cytosol] (Xenopus tropicalis)
HSPA6:ADP [cytosol] (Homo sapiens)
CCT/TRiC:ADP [cytosol] (Mus musculus)
CCT/TRiC:ADP [cytosol] (Drosophila melanogaster)
CCT/TRiC:ADP [cytosol] (Gallus gallus)
CCT/TRiC:ADP [cytosol] (Danio rerio)
CCT/TRiC:ADP [cytosol] (Saccharomyces cerevisiae)
CCT/TRiC:ADP [cytosol] (Schizosaccharomyces pombe)
CCT/TRiC:ADP [cytosol] (Dictyostelium discoideum)
CCT/TRiC:ADP [cytosol] (Plasmodium falciparum)
CCT/TRiC:ADP [cytosol] (Xenopus tropicalis)
CCT/TRiC:ADP [cytosol] (Bos taurus)
CCT/TRiC:ADP [cytosol] (Caenorhabditis elegans)
CCT/TRiC:ADP [cytosol] (Rattus norvegicus)
CCT/TRiC:ADP [cytosol] (Sus scrofa)
CCT/TRiC:ADP [cytosol] (Canis familiaris)
CCT/TRiC:ADP [cytosol] (Homo sapiens)
Myosin-Actin filaments [cytosol] (Sus scrofa)
Myosin-Actin filaments [cytosol] (Canis familiaris)
Myosin-Actin filaments [cytosol] (Bos taurus)
Myosin-Actin filaments [cytosol] (Gallus gallus)
Myosin-Actin filaments [cytosol] (Mus musculus)
Myosin-Actin filaments [cytosol] (Rattus norvegicus)
Myosin-Actin filaments [cytosol] (Homo sapiens)
Actin:ADP [cytosol] (Drosophila melanogaster)
Actin:ADP [cytosol] (Caenorhabditis elegans)
Actin:ADP [cytosol] (Saccharomyces cerevisiae)
Actin:ADP [cytosol] (Danio rerio)
Actin:ADP [cytosol] (Bos taurus)
Actin:ADP [cytosol] (Gallus gallus)
Actin:ADP [cytosol] (Mus musculus)
Actin:ADP [cytosol] (Schizosaccharomyces pombe)
Actin:ADP [cytosol] (Dictyostelium discoideum)
Actin:ADP [cytosol] (Canis familiaris)
Actin:ADP [cytosol] (Sus scrofa)
Actin:ADP [cytosol] (Xenopus tropicalis)
Actin:ADP [cytosol] (Rattus norvegicus)
Actin:ADP [cytosol] (Homo sapiens)
Actin filament bound Myosin-X [plasma membrane] (Canis familiaris)
Actin filament bound Myosin-X [plasma membrane] (Mus musculus)
Actin filament bound Myosin-X [plasma membrane] (Bos taurus)
Actin filament bound Myosin-X [plasma membrane] (Rattus norvegicus)
Actin filament bound Myosin-X [plasma membrane] (Sus scrofa)
Actin filament bound Myosin-X [plasma membrane] (Homo sapiens)
APAF1:ADP [cytosol] (Sus scrofa)
APAF1:ADP [cytosol] (Mus musculus)
APAF1:ADP [cytosol] (Drosophila melanogaster)
APAF1:ADP [cytosol] (Canis familiaris)
APAF1:ADP [cytosol] (Bos taurus)
APAF1:ADP [cytosol] (Gallus gallus)
APAF1:ADP [cytosol] (Danio rerio)
APAF1:ADP [cytosol] (Xenopus tropicalis)
APAF1:ADP [cytosol] (Rattus norvegicus)
APAF1:ADP [cytosol] (Homo sapiens)
as an input of
1,3-bisphosphoglycerate + ADP <=> 3-phosphoglycerate + ATP (Gallus gallus)
phosphoenolpyruvate + ADP => pyruvate + ATP (Gallus gallus)
ABCC4 accumulation of dense granule contents (Plasmodium falciparum)
ABCC4 accumulation of dense granule contents (Dictyostelium discoideum)
ABCC4 accumulation of dense granule contents (Caenorhabditis elegans)
ABCC4 accumulation of dense granule contents (Drosophila melanogaster)
ABCC4 accumulation of dense granule contents (Gallus gallus)
ABCC4 accumulation of dense granule contents (Danio rerio)
ABCC4 accumulation of dense granule contents (Sus scrofa)
ABCC4 accumulation of dense granule contents (Bos taurus)
ABCC4 accumulation of dense granule contents (Canis familiaris)
ABCC4 accumulation of dense granule contents (Rattus norvegicus)
ABCC4 accumulation of dense granule contents (Mus musculus)
ABCC4 accumulation of dense granule contents (Homo sapiens)
CHL1 interacts with Hsc70 (Mus musculus)
CHL1 interacts with HSP7C (Homo sapiens)
Phosphorylated Ire1 Dimer Binds ADP (Saccharomyces cerevisiae)
Phosphorylated IRE1 dimer binds ADP (Homo sapiens)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Danio rerio)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Bos taurus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Mus musculus)
ARL2:GTP:ARL2BP:SLC25A4 dimer exchanges ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Plasmodium falciparum)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Saccharomyces cerevisiae)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Schizosaccharomyces pombe)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Dictyostelium discoideum)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Caenorhabditis elegans)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Drosophila melanogaster)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Gallus gallus)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Xenopus tropicalis)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Danio rerio)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Sus scrofa)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Bos taurus)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Canis familiaris)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Rattus norvegicus)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Mus musculus)
(d)NTP + ADP <=> (d)NDP + ATP (NME1,2,3) (Homo sapiens)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Plasmodium falciparum)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Caenorhabditis elegans)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Drosophila melanogaster)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Gallus gallus)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Xenopus tropicalis)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Danio rerio)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Bos taurus)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Canis familiaris)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Rattus norvegicus)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Mus musculus)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Homo sapiens)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Plasmodium falciparum)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Saccharomyces cerevisiae)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Schizosaccharomyces pombe)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Dictyostelium discoideum)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Caenorhabditis elegans)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Drosophila melanogaster)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Gallus gallus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Xenopus tropicalis)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Danio rerio)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Sus scrofa)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Bos taurus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Canis familiaris)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Rattus norvegicus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Mus musculus)
(d)GDP + ADP <=> (d)GMP + ATP (GUK1) (Homo sapiens)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Plasmodium falciparum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Saccharomyces cerevisiae)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Schizosaccharomyces pombe)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Dictyostelium discoideum)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Caenorhabditis elegans)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Drosophila melanogaster)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Gallus gallus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Xenopus tropicalis)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Danio rerio)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Sus scrofa)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Bos taurus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Canis familiaris)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Rattus norvegicus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Mus musculus)
dUDP or TDP + ADP <=> dUMP or TMP + ATP [DTYMK] (Homo sapiens)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Plasmodium falciparum)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Saccharomyces cerevisiae)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Schizosaccharomyces pombe)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Dictyostelium discoideum)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Caenorhabditis elegans)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Drosophila melanogaster)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Gallus gallus)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Danio rerio)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Sus scrofa)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Bos taurus)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Canis familiaris)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Rattus norvegicus)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Mus musculus)
(d)CDP or UDP + ADP <=> (d)CMP or UMP + ATP (CMPK1) (Homo sapiens)
ADP + ADP <=> AMP + ATP [AK2] (Plasmodium falciparum)
ADP + ADP <=> AMP + ATP [AK2] (Saccharomyces cerevisiae)
ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)
ADP + ADP <=> AMP + ATP [AK2] (Dictyostelium discoideum)
ADP + ADP <=> AMP + ATP [AK2] (Caenorhabditis elegans)
ADP + ADP <=> AMP + ATP [AK2] (Drosophila melanogaster)
ADP + ADP <=> AMP + ATP [AK2] (Gallus gallus)
ADP + ADP <=> AMP + ATP [AK2] (Xenopus tropicalis)
ADP + ADP <=> AMP + ATP [AK2] (Danio rerio)
ADP + ADP <=> AMP + ATP [AK2] (Sus scrofa)
ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)
ADP + ADP <=> AMP + ATP [AK2] (Canis familiaris)
ADP + ADP <=> AMP + ATP [AK2] (Rattus norvegicus)
ADP + ADP <=> AMP + ATP [AK2] (Mus musculus)
ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Plasmodium falciparum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Schizosaccharomyces pombe)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Dictyostelium discoideum)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Xenopus tropicalis)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Saccharomyces cerevisiae)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Caenorhabditis elegans)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Drosophila melanogaster)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Gallus gallus)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Danio rerio)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Sus scrofa)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Bos taurus)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Canis familiaris)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Caenorhabditis elegans)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Drosophila melanogaster)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Gallus gallus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Sus scrofa)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Bos taurus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Canis familiaris)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Rattus norvegicus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Mus musculus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Homo sapiens)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Rattus norvegicus)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Homo sapiens)
SLC25A5,6 dimers exchange ATP for ADP across the mitochondrial inner membrane (Mus musculus)
PKM dephosphorylates PEP to PYR (Plasmodium falciparum)
PKM dephosphorylates PEP to PYR (Saccharomyces cerevisiae)
PKM dephosphorylates PEP to PYR (Schizosaccharomyces pombe)
PKM dephosphorylates PEP to PYR (Dictyostelium discoideum)
PKM dephosphorylates PEP to PYR (Caenorhabditis elegans)
PKM dephosphorylates PEP to PYR (Drosophila melanogaster)
PKM dephosphorylates PEP to PYR (Gallus gallus)
PKM dephosphorylates PEP to PYR (Xenopus tropicalis)
PKM dephosphorylates PEP to PYR (Danio rerio)
PKM dephosphorylates PEP to PYR (Sus scrofa)
PKM dephosphorylates PEP to PYR (Bos taurus)
PKM dephosphorylates PEP to PYR (Canis familiaris)
PKM dephosphorylates PEP to PYR (Rattus norvegicus)
PKM dephosphorylates PEP to PYR (Mus musculus)
PKM dephosphorylates PEP to PYR (Homo sapiens)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Plasmodium falciparum)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Saccharomyces cerevisiae)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Schizosaccharomyces pombe)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Dictyostelium discoideum)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Caenorhabditis elegans)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Drosophila melanogaster)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Gallus gallus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Danio rerio)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Sus scrofa)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Bos taurus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Canis familiaris)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Rattus norvegicus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Mus musculus)
1,3-bisphospho-D-glycerate + ADP <=> 3-phospho-D-glycerate + ATP (Homo sapiens)
ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)
ADPGK:Mg2+ phosphorylates Glc to G6P (Caenorhabditis elegans)
ADPGK:Mg2+ phosphorylates Glc to G6P (Gallus gallus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)
ADPGK:Mg2+ phosphorylates Glc to G6P (Danio rerio)
ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)
ADPGK:Mg2+ phosphorylates Glc to G6P (Bos taurus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Canis familiaris)
ADPGK:Mg2+ phosphorylates Glc to G6P (Rattus norvegicus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Homo sapiens)
as an output of
DAkt1-mediated phosphorylation inactivates DFOXO (Drosophila melanogaster)
Activated DTOR phosphorylates DS6K (Drosophila melanogaster)
Activated DTOR also phosphorylates D4EBP (Drosophila melanogaster)
Autophosphorylation of DINR (Drosophila melanogaster)
Chico is phosphorylated (Drosophila melanogaster)
Phosphorylation of PIP2 to PIP3 by Dp110 (Drosophila melanogaster)
Activation of DAkt1 by DPDK1 (Drosophila melanogaster)
Activated DAkt1 phosphorylates TSC2 which inhibits the TSC1/2 complex (Drosophila melanogaster)
DTOR is positively regulated by DRheb-GTP (Drosophila melanogaster)
DPDK1 phosphorylates and activates DS6K (Drosophila melanogaster)
Phosphorylated HOP phosphorylates DOME (Drosophila melanogaster)
STAT92E is phosphorylated by phosphorylated HOP (Drosophila melanogaster)
Activated HOP is autophosphorylated and/or transphosphorylated (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
CACT and DL dimer are phosphorylated in TL:WEK:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
Activated PLL kinase is autophosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
CACT and DL/DIF dimer are phosphorylated in TL:MYD88:TUB:PLL 'signalling complex' (Drosophila melanogaster)
ROK phosphorylates MBS (Drosophila melanogaster)
ROK phosphorylates SQH (Drosophila melanogaster)
Human APC is further phosphorylated by Murine CKIepsilon (Homo sapiens)
Murine Axin1 is further phosphorylated by Human GSK3beta (Mus musculus)
Human APC is further phosphorylated by Murine GSK3beta (Homo sapiens)
Human APC is initially phosphorylated by Murine CKIepsilon (Homo sapiens)
Frog CKIgamma further phosphorylates Human LRP6 in the receptor complex (Homo sapiens)
Membrane localised SGG phosphorylates ARR (Drosophila melanogaster)
GISH further phosphorylates ARR in the receptor complex (Drosophila melanogaster)
Human APC is finally phosphorylated by Murine GSK3beta (Homo sapiens)
Further phosphorylation of APC by SGG (Drosophila melanogaster)
Phosphorylation of ARM by CKIalpha (Drosophila melanogaster)
Further phosphorylation of ARM by SGG (Drosophila melanogaster)
Phosphorylation of AXN and APC by DCO (Drosophila melanogaster)
Phosphorylation of AXN and APC by SGG (Drosophila melanogaster)
Further phosphorylation of APC by DCO (Drosophila melanogaster)
Phosphorylated HPO dimer phosphorylates TH (Drosophila melanogaster)
HPO dimer autophosphorylates (Drosophila melanogaster)
Phosphorylated HPO dimer phosphorylates SAV (Drosophila melanogaster)
Phosphorylated HPO dimer phosphorylates WTS (Drosophila melanogaster)
MATS is phosphorylated by HPO dimer and binds to phosphorylated WTS (Drosophila melanogaster)
Phosphorylated WTS autophosphorylates (Drosophila melanogaster)
YKI is phosphorylated by and then dissociates from phosphorylated WTS (Drosophila melanogaster)
FT is phosphorylated by DCO (Drosophila melanogaster)
CRY is phosphorylated by SGG (Drosophila melanogaster)
PER is phosphorylated by DCO (Drosophila melanogaster)
Phosphorylated PER is phosphorylated by CK2 (Drosophila melanogaster)
TIM is phosphorylated by CK2 (Drosophila melanogaster)
Liberation of CI from SU(FU) repression (Drosophila melanogaster)
Phosphorylation of SMO by PKA-C1 (Drosophila melanogaster)
Phosphorylation of SMO by CKIalpha (Drosophila melanogaster)
Autophosphorylated FU phosphorylates COS (Drosophila melanogaster)
Phosphorylation of CI by PKA-C1 (Drosophila melanogaster)
Phosphorylation of CI by CKIalphaepsilon (CKIalpha/DCO) (Drosophila melanogaster)
Phosphorylation of CI by SGG (Drosophila melanogaster)
Further phosphorylation of CI by CKIalphaepsilon (Drosophila melanogaster)
RAC1:GTP and MSN activate HEP (Drosophila melanogaster)
BSK is phosphorylated and activated by phosphorylated HEP kinase (Drosophila melanogaster)
CKA is phosphorylated by phosphorylated BSK kinase (Drosophila melanogaster)
Murine MKK4 kinase is phosphorylated and activated by Phospho TAK1:Phospho TAB1:Phospho TAB2 kinase complex (Mus musculus)
HEP is phosphorylated and activated by Phospho TAK1:TAB2 kinase complex (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the PGN:PGRP-LC oligomer receptor 'signalling complex' (Drosophila melanogaster)
Activated TAK1 kinase is autophosphorylated (Drosophila melanogaster)
Activated phosphorylated TAK1 kinase phosphorylates and activates IRD5 (Drosophila melanogaster)
Activated Phospho IRD5:KEY dimer phosphorylates REL in the monomeric PGN:PGRP-LE oligomer receptor 'signalling complex' (Drosophila melanogaster)
sphinganine (dihydrosphingosine) +ATP => sphinganine 1-phosphate + ADP (Gallus gallus)
fructose 6-phosphate + ATP => fructose 2,6-bisphosphate + ADP (Gallus gallus)
L-glutamine + 2 ATP + HCO3- + H2O => carbamoyl phosphate + L-glutamate + 2 ADP + orthophosphate (Gallus gallus)
5-phosphoribosylamine + glycine + ATP <=> 5-phosphoribosylglycinamide (GAR) + adenosine 5'-diphosphate + orthophosphate (Gallus gallus)
5'-phosphoribosylformylglycinamide (FGAR) + L-glutamine + ATP + H2O => 5'-phosphoribosylformylglycinamidine (FGAM) + L-glutamate + ADP + orthophosphate (Gallus gallus)
5'-phosphoribosylformylglycinamidine (FGAM) + ATP => 5'-phosphoribosyl-5-aminoimidazole (AIR) + ADP + orthophosphate (Gallus gallus)
5'-phosphoribosyl-5-aminoimidazole-4-carboxylate (CAIR) + L-aspartate + ATP => 5'-phosphoribosyl-5-aminoimidazole-4-N-succinocarboxamide (SAICAR) + adenosine 5'-diphosphate + orthophosphate (Gallus gallus)
glucose + ATP => glucose 6-phosphate + ADP (Gallus gallus)
fructose 6-phosphate + ATP => fructose 1,6-bisphosphate + ADP (Gallus gallus)
3-phosphoglycerate + ATP <=> 1,3-bisphosphoglycerate + ADP (Gallus gallus)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 upon TLR7 or 21 stimulation (Gallus gallus)
IRAK2 phosphorylation bound to the activated TLR7 (or TLR21) complex (Gallus gallus)
Autophosphorylation of IRAK4 bound to the activated TLR7 or 21complex. (Gallus gallus)
Autophosphorylation of IRAK4 bound to activated TLR5 or 15 (Gallus gallus)
Activated IRAK4 bound to activated TLR : MyD88 complex phosphorylates IRAK2 (Gallus gallus)
Phosphorylation of IRF3 by TBK1 complexed with activated TLR3 (Gallus gallus)
TBK1/IKK epsilon bind to TANK:TRAF3/TRAF6 complex followed by their activation (Gallus gallus)
Phosphorylation and release of IRF3 (Gallus gallus)
IKK epsilon is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
TBK1 is recruited to the Viral dsRNA:TLR3:TICAM1 complex (Gallus gallus)
Phosphorylation of IRF3 by IKK epsilon(IKBKE) complexed with activated TLR3. (Gallus gallus)
phosphorylation of IRAK2 by activated IRAK4 (Gallus gallus)
Phosphorylation of MKK3/MKK6 by activated TAK1 (Gallus gallus)
Phosphorylation of MKK4 by activated TAK1 (Gallus gallus)
MKK4 phosphorylates JNK (Gallus gallus)
activated MEK2 phosphorylates ERK2 (Gallus gallus)
Autophosphorylation of chicken IRAK4 (Gallus gallus)
ESCRT Disassembly (Saccharomyces cerevisiae)
ESCRT Disassembly (Schizosaccharomyces pombe)
ESCRT Disassembly (Dictyostelium discoideum)
ESCRT Disassembly (Drosophila melanogaster)
ESCRT Disassembly (Gallus gallus)
ESCRT Disassembly (Xenopus tropicalis)
ESCRT Disassembly (Sus scrofa)
ESCRT Disassembly (Bos taurus)
ESCRT Disassembly (Rattus norvegicus)
ESCRT Disassembly (Mus musculus)
ESCRT Disassembly (Homo sapiens)
ADBRK1,2 phosphorylate AVPR2 (Xenopus tropicalis)
ADBRK1,2 phosphorylate AVPR2 (Sus scrofa)
ADBRK1,2 phosphorylate AVPR2 (Bos taurus)
ADBRK1,2 phosphorylate AVPR2 (Canis familiaris)
ADBRK1,2 phosphorylate AVPR2 (Rattus norvegicus)
ADBRK1,2 phosphorylate AVPR2 (Mus musculus)
ADBRK1,2 phosphorylate AVPR2 (Homo sapiens)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Dictyostelium discoideum)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Caenorhabditis elegans)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Drosophila melanogaster)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Gallus gallus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Sus scrofa)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Bos taurus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Canis familiaris)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Rattus norvegicus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Mus musculus)
Clathrin-associated PIK3C2A phosphorylates PI(4)P to PI(3,4)P2 (Homo sapiens)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Plasmodium falciparum)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Saccharomyces cerevisiae)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Schizosaccharomyces pombe)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Dictyostelium discoideum)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Caenorhabditis elegans)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Drosophila melanogaster)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Gallus gallus)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Xenopus tropicalis)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Sus scrofa)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Bos taurus)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Canis familiaris)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Rattus norvegicus)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Mus musculus)
PIP5K1C phosphorylates PI(4)P to PI(4,5)P2 (Homo sapiens)
AAK1 phosphorylates AP-2 mu subunit at T156 (Saccharomyces cerevisiae)
AAK1 phosphorylates AP-2 mu subunit at T156 (Schizosaccharomyces pombe)
AAK1 phosphorylates AP-2 mu subunit at T156 (Dictyostelium discoideum)
AAK1 phosphorylates AP-2 mu subunit at T156 (Caenorhabditis elegans)
AAK1 phosphorylates AP-2 mu subunit at T156 (Drosophila melanogaster)
AAK1 phosphorylates AP-2 mu subunit at T156 (Gallus gallus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Sus scrofa)
AAK1 phosphorylates AP-2 mu subunit at T156 (Bos taurus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Canis familiaris)
AAK1 phosphorylates AP-2 mu subunit at T156 (Rattus norvegicus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Mus musculus)
AAK1 phosphorylates AP-2 mu subunit at T156 (Homo sapiens)
trans-Golgi Network Derived Vesicle Uncoating (Canis familiaris)
trans-Golgi Network Derived Vesicle Uncoating (Rattus norvegicus)
trans-Golgi Network Derived Vesicle Uncoating (Mus musculus)
trans-Golgi Network Derived Vesicle Uncoating (Homo sapiens)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Canis familiaris)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Rattus norvegicus)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Mus musculus)
trans-Golgi Network Derived Lysosomal Vesicle Uncoating (Homo sapiens)
p-Akt2 phosphorylates C2cd5 (Mus musculus)
p-AKT2 phosphorylates C2CD5 (Homo sapiens)
Fusion of Glut4 Vesicle with the Plasma Membrane (Mus musculus)
SLC2A4 (GLUT4) vesicle fuses with the plasma membrane (Homo sapiens)
Akt2 Phosphorylates Rgc2 (Mus musculus)
p-AKT2 phosphorylates RGC2 (Homo sapiens)
p-AKT1,p-AKT2 phosphorylates AS160 (TBC1D4) (Homo sapiens)
Ampk-alpha2 Phosphorylates Tbc1d1 (Mus musculus)
AMPK-alpha2 phosphorylates TBC1D1 (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Saccharomyces cerevisiae)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Schizosaccharomyces pombe)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Dictyostelium discoideum)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Gallus gallus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Sus scrofa)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Bos taurus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Canis familiaris)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Rattus norvegicus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Mus musculus)
ATP hydrolysis by NSF disassembles the cis-SNARE at the Golgi membrane (Homo sapiens)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Caenorhabditis elegans)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Drosophila melanogaster)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Gallus gallus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Bos taurus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Rattus norvegicus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Mus musculus)
Dynein drives COPI-independent retrograde traffic from the Golgi to the ER (Homo sapiens)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Gallus gallus)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Bos taurus)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Rattus norvegicus)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Mus musculus)
NSF-dependent ATP hydrolysis disassembles the cis-SNARE at the TGN (Homo sapiens)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Dictyostelium discoideum)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Drosophila melanogaster)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Canis familiaris)
ATP hydrolysis by NSF disassembles the cis-SNARE at the TGN (Homo sapiens)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Dictyostelium discoideum)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Caenorhabditis elegans)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Drosophila melanogaster)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Gallus gallus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Rattus norvegicus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Mus musculus)
Active AKT phosphorylates DENND1A and DENND1B in response to insulin signaling (Homo sapiens)
p-ULK1 phosphorylates DENND3 (Schizosaccharomyces pombe)
p-ULK1 phosphorylates DENND3 (Dictyostelium discoideum)
p-ULK1 phosphorylates DENND3 (Gallus gallus)
p-ULK1 phosphorylates DENND3 (Sus scrofa)
p-ULK1 phosphorylates DENND3 (Bos taurus)
p-ULK1 phosphorylates DENND3 (Canis familiaris)
p-ULK1 phosphorylates DENND3 (Rattus norvegicus)
p-ULK1 phosphorylates DENND3 (Mus musculus)
p-ULK1 phosphorylates DENND3 (Homo sapiens)
Jak2 Phosphorylates Irs1/2 in Response to Leptin (Mus musculus)
JAK2 Phosphorylates IRS in Response to Leptin (Homo sapiens)
Jak2 Phosphorylates Shp2 in Response to Leptin (Mus musculus)
JAK2 Phosphorylates SHP2 (PTPN11) in Response to Leptin (Homo sapiens)
JAK2 Phosphorylates STAT5 in Response to Leptin (Homo sapiens)
MST1R autophosphorylates (Caenorhabditis elegans)
MST1R autophosphorylates (Gallus gallus)
MST1R autophosphorylates (Xenopus tropicalis)
MST1R autophosphorylates (Danio rerio)
MST1R autophosphorylates (Sus scrofa)
MST1R autophosphorylates (Bos taurus)
MST1R autophosphorylates (Canis familiaris)
MST1R autophosphorylates (Rattus norvegicus)
MST1R autophosphorylates (Mus musculus)
MST1R autophosphorylates (Homo sapiens)
Jak2 phosphorylates Vav1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef1:p-Y-Shc1:Grb2-1:Vav1 (Mus musculus)
JAK2 phosphorylates VAV1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:p-Y-CRKL:RASGEF1:p-Y-SHC1:GRB2:VAV1 (Homo sapiens)
Jak2 phosphorylates Shc1 in Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2:p-Crkl:Rapgef:Shc1 (Mus musculus)
JAK2 phosphorylates SHC1 in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:p-CRKL:RABGEF1:SHC1 (Homo sapiens)
LYN phosphorylates CRKL in EPO:p-8Y-EPOR:p-12Y-JAK2:LYN:IRS2:CRKL:RAPGEF1 (Homo sapiens)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
EPOR-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Xenopus tropicalis)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Sus scrofa)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Bos taurus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Canis familiaris)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Rattus norvegicus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Mus musculus)
EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 phosphorylates IRS2 (Homo sapiens)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Xenopus tropicalis)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Sus scrofa)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Bos taurus)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Canis familiaris)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Rattus norvegicus)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Mus musculus)
JAK2 phosphorylates GAB1 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:GAB1 (Homo sapiens)
Lyn phosphorylates Plcg1,2 in Epo:phospho-Epor:phospho-Jak2:Lyn:Irs2:Plcg1,2 (Mus musculus)
LYN phosphorylates PLCG1,2 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2:PLCG1,2 (Homo sapiens)
Src phosphorylates RHOU (Homo sapiens)
SRC phosphorylates RHOU (Homo sapiens)
PAK1,2,3 phosphorylates MAPK6,4 (Saccharomyces cerevisiae)
PAK1,2,3 phosphorylates MAPK6,4 (Schizosaccharomyces pombe)
PAK1,2,3 phosphorylates MAPK6,4 (Dictyostelium discoideum)
PAK1,2,3 phosphorylates MAPK6,4 (Caenorhabditis elegans)
PAK1,2,3 phosphorylates MAPK6,4 (Gallus gallus)
PAK1,2,3 phosphorylates MAPK6,4 (Xenopus tropicalis)
PAK1,2,3 phosphorylates MAPK6,4 (Danio rerio)
PAK1,2,3 phosphorylates MAPK6,4 (Sus scrofa)
PAK1,2,3 phosphorylates MAPK6,4 (Bos taurus)
PAK1,2,3 phosphorylates MAPK6,4 (Canis familiaris)
PAK1,2,3 phosphorylates MAPK6,4 (Rattus norvegicus)
PAK1,2,3 phosphorylates MAPK6,4 (Mus musculus)
PAK1,2,3 phosphorylates MAPK6,4 (Homo sapiens)
MAPKAPK5 phosphorylates KALRN (Gallus gallus)
MAPKAPK5 phosphorylates KALRN (Rattus norvegicus)
MAPKAPK5 phosphorylates KALRN (Mus musculus)
MAPKAPK5 phosphorylates KALRN (Homo sapiens)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Gallus gallus)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Danio rerio)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Sus scrofa)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Bos taurus)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Rattus norvegicus)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Mus musculus)
SEPT7:p-S189 MAPK6:p-T182 MAPKAPK5 phosphorylates CDC42EPs (Homo sapiens)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Gallus gallus)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Danio rerio)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Sus scrofa)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Bos taurus)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Rattus norvegicus)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Mus musculus)
p-T182 MAPKAPK5 phosphorylates FOXO3 (Homo sapiens)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Plasmodium falciparum)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Gallus gallus)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Danio rerio)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Sus scrofa)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Bos taurus)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Rattus norvegicus)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Mus musculus)
p-T182-MAPKAPK5 phoshphorylates DNAJB1 (Homo sapiens)
p-S MAPKAPK5 phosphorylates HSPB1 (Gallus gallus)
p-S MAPKAPK5 phosphorylates HSPB1 (Danio rerio)
p-S MAPKAPK5 phosphorylates HSPB1 (Sus scrofa)
p-S MAPKAPK5 phosphorylates HSPB1 (Bos taurus)
p-S MAPKAPK5 phosphorylates HSPB1 (Rattus norvegicus)
p-S MAPKAPK5 phosphorylates HSPB1 (Mus musculus)
p-S MAPKAPK5 phosphorylates HSPB1 (Homo sapiens)
Atp2b1 (Pmca1) transports Ca2+ from the cytosol to the extracellular region (Rattus norvegicus)
ATP2B1 (PMCA1) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
Atp2b2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Rattus norvegicus)
Atp2b2 (PMCA2) transports Ca2+ from the cytosol to the extracellular region (Mus musculus)
ATP2B2-wa (PMCA2-wa) transports Ca2+ from the cytosol to the extracellular region (Homo sapiens)
SBH1:GET3:ADP:GET1:GET2 dissociates yielding SBH1 in the endoplasmic reticulum membrane (Saccharomyces cerevisiae)
Tail-anchored protein:ASNA1:ADP:WRB:CAMLG dissociates yielding Tail-anchored protein in the endoplasmic reticulum membrane (Homo sapiens)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Gallus gallus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Sus scrofa)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Bos taurus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Rattus norvegicus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Mus musculus)
PEX1:PEX6:PEX26:ZFAND6 dissociates Ub:PEX5L and PEX7 from PEX14:PEX13:PEX2:PEX10:PEX12 and translocates PEX5L and PEX7 from the peroxisomal membrane to the cytosol (Homo sapiens)
PEX1:PEX6:PEX15:Ub:PEX5:PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX17:PEX1:PEX6:PEX15 (Saccharomyces cerevisiae)
PEX1:PEX6:PEX26:ZFAND6:Ub:PEX5S,L:PEX14:PEX13:PEX2:PEX10:PEX12 dissociates yielding cytosolic Ub:PEX5S,L and membrane PEX14:PEX13:PEX2:PEX10:PEX12 (Homo sapiens)
Phosphorylation of shikimate (Mycobacterium tuberculosis)
APS is phosphorylated to PAPS (Mycobacterium tuberculosis)
sulfate uptake in the cytosol (Mycobacterium tuberculosis)
Release Of ADP From Myosin (Gallus gallus)
Release Of ADP From Myosin (Sus scrofa)
Release Of ADP From Myosin (Bos taurus)
Release Of ADP From Myosin (Canis familiaris)
Release Of ADP From Myosin (Rattus norvegicus)
Release Of ADP From Myosin (Mus musculus)
Release Of ADP From Myosin (Homo sapiens)
PRKACA phosphorylates TNNI3 (Caenorhabditis elegans)
PRKACA phosphorylates TNNI3 (Drosophila melanogaster)
PRKACA phosphorylates TNNI3 (Xenopus tropicalis)
PRKACA phosphorylates TNNI3 (Danio rerio)
PRKACA phosphorylates TNNI3 (Sus scrofa)
PRKACA phosphorylates TNNI3 (Canis familiaris)
PRKACA phosphorylates TNNI3 (Rattus norvegicus)
PRKACA phosphorylates TNNI3 (Mus musculus)
PRKACA phosphorylates TNNI3 (Homo sapiens)
PRKACA phosphorylates PLN (Xenopus tropicalis)
PRKACA phosphorylates PLN (Sus scrofa)
PRKACA phosphorylates PLN (Bos taurus)
PRKACA phosphorylates PLN (Canis familiaris)
PRKACA phosphorylates PLN (Rattus norvegicus)
PRKACA phosphorylates PLN (Mus musculus)
PRKACA phosphorylates PLN (Homo sapiens)
Release Of ADP From Myosin (Rattus norvegicus)
Release Of ADP From Myosin (Caenorhabditis elegans)
Release Of ADP From Myosin (Drosophila melanogaster)
Release Of ADP From Myosin (Gallus gallus)
Release Of ADP From Myosin (Sus scrofa)
Release Of ADP From Myosin (Bos taurus)
Release Of ADP From Myosin (Canis familiaris)
Release Of ADP From Myosin (Mus musculus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Gallus gallus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Sus scrofa)
Phosphorylation of Smooth Muscle Myosin Light Chains (Bos taurus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Canis familiaris)
Phosphorylation of Smooth Muscle Myosin Light Chains (Rattus norvegicus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Mus musculus)
Phosphorylation of Smooth Muscle Myosin Light Chains (Homo sapiens)
Release Of ADP From Myosin (Homo sapiens)
Phosphorylation of Khsrp by p38 (Mus musculus)
MAP kinase p38 phosphorylates KSRP (Homo sapiens)
Protein Kinase B (AKT) phosphorylates KSRP (Caenorhabditis elegans)
Protein Kinase B (AKT) phosphorylates KSRP (Drosophila melanogaster)
Protein Kinase B (AKT) phosphorylates KSRP (Danio rerio)
Protein Kinase B (AKT) phosphorylates KSRP (Rattus norvegicus)
Protein Kinase B (AKT) phosphorylates KSRP (Mus musculus)
Protein Kinase B (AKT) phosphorylates KSRP (Homo sapiens)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Caenorhabditis elegans)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Drosophila melanogaster)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Sus scrofa)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Bos taurus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Rattus norvegicus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Mus musculus)
MK2 phosphorylates ZFP36 (Tristetraproline, TTP) (Homo sapiens)
MK2 phosphorylates BRF1 (Caenorhabditis elegans)
MK2 phosphorylates BRF1 (Drosophila melanogaster)
MK2 phosphorylates BRF1 (Gallus gallus)
MK2 phosphorylates BRF1 (Danio rerio)
MK2 phosphorylates BRF1 (Sus scrofa)
MK2 phosphorylates BRF1 (Bos taurus)
MK2 phosphorylates BRF1 (Rattus norvegicus)
MK2 phosphorylates BRF1 (Mus musculus)
MK2 phosphorylates BRF1 (Homo sapiens)
Protein Kinase B/Akt phosphorylates BRF1 (Saccharomyces cerevisiae)
Protein Kinase B/Akt phosphorylates BRF1 (Schizosaccharomyces pombe)
Protein Kinase B/Akt phosphorylates BRF1 (Dictyostelium discoideum)
Protein Kinase B/Akt phosphorylates BRF1 (Caenorhabditis elegans)
Protein Kinase B/Akt phosphorylates BRF1 (Drosophila melanogaster)
Protein Kinase B/Akt phosphorylates BRF1 (Gallus gallus)
Protein Kinase B/Akt phosphorylates BRF1 (Danio rerio)
Protein Kinase B/Akt phosphorylates BRF1 (Rattus norvegicus)
Protein Kinase B/Akt phosphorylates BRF1 (Mus musculus)
Protein Kinase B/Akt phosphorylates BRF1 (Homo sapiens)
ADP is exchanged for ATP in the ADP:CCT/TriC:tubulin complex (Mus musculus)
ADP is exchanged for ATP in the (ADP:CCT/TriC):tubulin complex (Homo sapiens)
Exchange of ADP for ATP in CCT/TriC:actin complex (Bos taurus)
Exchange of ADP for ATP in CCT/TriC:actin complex (Homo sapiens)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Dictyostelium discoideum)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Xenopus tropicalis)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Sus scrofa)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Bos taurus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Canis familiaris)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Rattus norvegicus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Mus musculus)
TTLL3, TTLL8, TTLL10 polyglycylate tubulin (Homo sapiens)
TTLLs polyglutamylate tubulin (Plasmodium falciparum)
TTLLs polyglutamylate tubulin (Xenopus tropicalis)
TTLLs polyglutamylate tubulin (Sus scrofa)
TTLLs polyglutamylate tubulin (Bos taurus)
TTLLs polyglutamylate tubulin (Canis familiaris)
TTLLs polyglutamylate tubulin (Rattus norvegicus)
TTLLs polyglutamylate tubulin (Mus musculus)
TTLLs polyglutamylate tubulin (Homo sapiens)
Polyglutamylase complex (Ttll1) polyglutamylates alpha subunits of tubulin (Homo sapiens)
Polyglutamylase complex (TTLL1) polyglutamylates alpha subunits of tubulin (Homo sapiens)
TTL ligates L-Tyr to the carboxy terminus of alpha-tubulin (Bos taurus)
TTL ligates L-Tyr to the carboxy terminus of detyr-alpha tubulin:beta tubulin (Homo sapiens)
PI is phosphorylated to PI5P by Pikfyve at the late endosome membrane (Mus musculus)
PI is phosphorylated to PI5P by PIKFYVE at the late endosome membrane (Homo sapiens)
BMX phosphorylates RUFY1 (Drosophila melanogaster)
BMX phosphorylates RUFY1 (Gallus gallus)
BMX phosphorylates RUFY1 (Sus scrofa)
BMX phosphorylates RUFY1 (Bos taurus)
BMX phosphorylates RUFY1 (Canis familiaris)
BMX phosphorylates RUFY1 (Rattus norvegicus)
BMX phosphorylates RUFY1 (Mus musculus)
BMX phosphorylates RUFY1 (Homo sapiens)
Casein kinase II phosphorylates STARD10 (Caenorhabditis elegans)
Casein kinase II phosphorylates STARD10 (Sus scrofa)
Casein kinase II phosphorylates STARD10 (Bos taurus)
Casein kinase II phosphorylates STARD10 (Canis familiaris)
Casein kinase II phosphorylates STARD10 (Rattus norvegicus)
Casein kinase II phosphorylates STARD10 (Mus musculus)
Casein kinase II phosphorylates STARD10 (Homo sapiens)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
Btn-ACACB:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Plasmodium falciparum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Saccharomyces cerevisiae)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Schizosaccharomyces pombe)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Dictyostelium discoideum)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Caenorhabditis elegans)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Drosophila melanogaster)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Gallus gallus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Xenopus tropicalis)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Sus scrofa)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Bos taurus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Canis familiaris)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Rattus norvegicus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Mus musculus)
Btn-ACACA:2Mn2+ polymer carboxylates Ac-CoA to form Mal-CoA (Homo sapiens)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Saccharomyces cerevisiae)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Schizosaccharomyces pombe)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Dictyostelium discoideum)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Caenorhabditis elegans)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Drosophila melanogaster)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Sus scrofa)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Bos taurus)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Canis familiaris)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Rattus norvegicus)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Mus musculus)
pAMPK inactivates ACACB, inhibiting malonyl-CoA synthesis (Homo sapiens)
perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP (Mus musculus)
perilipin + 3 ATP -> phosphorylated perilipin + 3 ADP (Rattus norvegicus)
perilipin + 2 ATP -> phosphorylated perilipin + 2 ADP (Homo sapiens)
hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP (Rattus norvegicus)
hormone-sensitive lipase (HSL) + 2 ATP -> phosphorylated HSL + 2 ADP (Homo sapiens)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Drosophila melanogaster)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Gallus gallus)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Danio rerio)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Sus scrofa)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Bos taurus)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Mus musculus)
5-PP-IP5 is phosphorylated to 5-PPP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Plasmodium falciparum)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Drosophila melanogaster)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Gallus gallus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Xenopus tropicalis)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Danio rerio)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Sus scrofa)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Bos taurus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Canis familiaris)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Rattus norvegicus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Mus musculus)
1-PP-IP4 is phosphorylated to 1,5-(PP)2-IP3 by IP6K1/3 in the cytosol (Homo sapiens)
Transport of antigen loaded MHC II molecules to surface (Sus scrofa)
Transport of antigen loaded MHC II molecules to surface (Bos taurus)
Transport of antigen loaded MHC II molecules to surface (Canis familiaris)
Transport of antigen loaded MHC II molecules to surface (Rattus norvegicus)
Transport of antigen loaded MHC II molecules to surface (Mus musculus)
Transport of antigen loaded MHC II molecules to surface (Homo sapiens)
PKA/PKG phosphorylate Rap1GAP2 (Caenorhabditis elegans)
PKA/PKG phosphorylate Rap1GAP2 (Drosophila melanogaster)
PKA/PKG phosphorylate Rap1GAP2 (Gallus gallus)
PKA/PKG phosphorylate Rap1GAP2 (Xenopus tropicalis)
PKA/PKG phosphorylate Rap1GAP2 (Danio rerio)
PKA/PKG phosphorylate Rap1GAP2 (Sus scrofa)
PKA/PKG phosphorylate Rap1GAP2 (Bos taurus)
PKA/PKG phosphorylate Rap1GAP2 (Canis familiaris)
PKA/PKG phosphorylate Rap1GAP2 (Rattus norvegicus)
PKA/PKG phosphorylate Rap1GAP2 (Mus musculus)
PKA/PKG phosphorylate Rap1GAP2 (Homo sapiens)
Csf1r-associated PI3K phosphorylates phosphatidylinositol 4,5-bisphosphate (Mus musculus)
CSF1R-associated phosphatidylinositol 3-kinase (PI3K) phosphorylates PI(4,5)P2 (Homo sapiens)
Src family kinases phosphorylate Cbl in Csf1 dimer:p-Y559-Csf1r dimer:Cbl (Mus musculus)
Src family kinases phosphorylate CBL in CSF1 dimer:p-Y561-CSF1R dimer:CBL (Homo sapiens)
Pik3r11:Pik3ca,b,d (Pi3k), Plcg2 (PLCgamma2), Grb2:Sos1, Shc1 (Shc), Ptpn11 (Shp2), Grb2:Gab2, Grb2:Gab3, Grap2 (MONA), Cbl:Grb2, Inpp5d (SHIP1), Inppl1 (SHIP2) bind p-8Y-Csf1r and are activated (Mus musculus)
PIK3R1:PIK3CA,B,D (PI3K), PLCG2 (PLCgamma2), SHC1 (SHC), PTPN11 (SHP2), GRB2:GAB2, GRB2:GAB3, GRAP2 (MONA), CBL:GRB2, INPP5D (SHIP1), INPPL1 (SHIP2) bind PolyUb,p-8Y-CSF1R and are activated (Homo sapiens)
Csf1r trans-autophosphoryates on tyrosine-559 (Mus musculus)
CSF1R trans-autophosphorylates on tyrosine-561 (Homo sapiens)
Csf1r trans-autophosphorylates on multiple tyrosine residues (Mus musculus)
CSF1R trans-autophosphorylates on multiple tyrosine and serine residues (Homo sapiens)
Jak2, Tyk2 in Il12b:Il23a:Il12rb1:Tyk2:Il23r:Jak2 are phosphorylated (Mus musculus)
JAK2, TYK2 in IL23A:IL12B:IL23R:JAK2:IL12RB1:TYK2 are phosphorylated (Homo sapiens)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Gallus gallus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Sus scrofa)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Bos taurus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Canis familiaris)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Rattus norvegicus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Mus musculus)
STAT3, STAT4 are phosphorylated by p-JAK2, p-TYK2 in IL23:IL23 receptor (Homo sapiens)
Il23r from Il23:Il23 receptor complex is phosphorylated (Mus musculus)
IL23R in IL23:IL23 receptor complex is phosphorylated (Homo sapiens)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Xenopus tropicalis)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Sus scrofa)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Bos taurus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Canis familiaris)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Rattus norvegicus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Mus musculus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Gallus gallus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Xenopus tropicalis)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Sus scrofa)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Bos taurus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Canis familiaris)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Rattus norvegicus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Mus musculus)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST are phosphorylated (Homo sapiens)
JAK1/JAK2/TYK2 bound to IL6ST:IL6ST phosphorylate STAT1 (Homo sapiens)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Gallus gallus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Xenopus tropicalis)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Sus scrofa)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Bos taurus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Canis familiaris)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Rattus norvegicus)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Mus musculus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Gallus gallus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Sus scrofa)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Bos taurus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Canis familiaris)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Mus musculus)
JAK1/JAK2 bound to IL35:IL6ST:IL12RB2 receptor are phosphorylated (Homo sapiens)
JAK1/JAK2 bound to IL12RB2:IL6ST receptor phosphorylates STAT1 and STAT4 (Homo sapiens)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Gallus gallus)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Xenopus tropicalis)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Sus scrofa)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Bos taurus)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Canis familiaris)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Rattus norvegicus)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Mus musculus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Gallus gallus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Xenopus tropicalis)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Sus scrofa)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Bos taurus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Canis familiaris)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Rattus norvegicus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Mus musculus)
JAK2 in IL12RB2:IL12RB2 receptor is phosphorylated (Homo sapiens)
JAK2 bound to IL12RB2:IL12RB2 phosphorylate STAT4 (Homo sapiens)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Gallus gallus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Xenopus tropicalis)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Sus scrofa)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Bos taurus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Canis familiaris)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Rattus norvegicus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Mus musculus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor phosphorylate STAT1,STAT3 (Homo sapiens)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Xenopus tropicalis)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Sus scrofa)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Bos taurus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Canis familiaris)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Rattus norvegicus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Mus musculus)
JAK1,JAK2 bound to IL27RA:IL12RB2 receptor are phosphorylated (Homo sapiens)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Gallus gallus)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Sus scrofa)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Bos taurus)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Canis familiaris)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Rattus norvegicus)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Mus musculus)
JAK2, TYK2 in IL12A:IL12RB1:TYK2:IL12B:IL12RB2:JAK2 are phosphorylated (Homo sapiens)
Stat4 is phosphorylated by p-Jak2 and/or p-Y-Tyk2 after Il12:Il12r interaction (Mus musculus)
STAT4 is phosphorylated by p-JAK2 and/or p-Y-TYK2 after IL12:IL12R interaction (Homo sapiens)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Gallus gallus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Sus scrofa)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Bos taurus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Canis familiaris)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Rattus norvegicus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Mus musculus)
IL12RB2 in IL12A:IL12RB1:p-Y-TYK2:IL12B:IL12RB2:p-JAK2 is phosphorylated (Homo sapiens)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Xenopus tropicalis)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Sus scrofa)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Bos taurus)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Canis familiaris)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Rattus norvegicus)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Mus musculus)
STAT3 and STAT1 are phosphorylated by JAKs after IL27:IL27R interaction (Homo sapiens)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Xenopus tropicalis)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Sus scrofa)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Bos taurus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Canis familiaris)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Rattus norvegicus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Mus musculus)
IL27RA and IL6ST are phosphorylated after IL27:IL27 receptor interaction and JAK's phosphorylation (Homo sapiens)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Xenopus tropicalis)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Sus scrofa)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Bos taurus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Canis familiaris)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Rattus norvegicus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Mus musculus)
JAK1, JAK2, TYK2 in IL27:EBI3:IL27RA:JAK1:IL6ST:(JAK1,JAK2,TYK2) are phosphorylated (Homo sapiens)
STAT1,STAT3,STAT6 phosphorylation (Gallus gallus)
STAT1,STAT3,STAT6 phosphorylation (Sus scrofa)
STAT1,STAT3,STAT6 phosphorylation (Bos taurus)
STAT1,STAT3,STAT6 phosphorylation (Canis familiaris)
STAT1,STAT3,STAT6 phosphorylation (Rattus norvegicus)
STAT1,STAT3,STAT6 phosphorylation (Mus musculus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Gallus gallus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Sus scrofa)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Bos taurus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Canis familiaris)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Rattus norvegicus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Mus musculus)
IL4R, IL13RA, JAK2 and TYK2 are tyrosine phosphorylated (Homo sapiens)
STAT1,STAT3,STAT6 phosphorylation (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Gallus gallus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Xenopus tropicalis)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Danio rerio)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Sus scrofa)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Bos taurus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Canis familiaris)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Rattus norvegicus)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Mus musculus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Gallus gallus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Xenopus tropicalis)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Danio rerio)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Sus scrofa)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Bos taurus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Canis familiaris)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Rattus norvegicus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Mus musculus)
IL26:IL20RA:JAK1:IL10RB:TYK2 phosphorylates JAK1, TYK2 (Homo sapiens)
IL26:IL10RB:p-TYK2:IL20RA:p-JAK1:STAT1,STAT3 phosphorylates STAT1,STAT3 (Homo sapiens)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Gallus gallus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Xenopus tropicalis)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Sus scrofa)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Bos taurus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Canis familiaris)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Rattus norvegicus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Mus musculus)
IFNL1:p-Y343,Y517-IFNLR1:p-JAK1:IL10RB:p-TYK2:STAT1 phosphorylates STAT1, STAT2, STAT3, STAT4 and STAT5 (Homo sapiens)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Sus scrofa)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Bos taurus)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Rattus norvegicus)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)
IL24:IL22RA1:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Gallus gallus)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Danio rerio)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)
IL24:IL22RA1:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Gallus gallus)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Sus scrofa)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Bos taurus)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Mus musculus)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Gallus gallus)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Danio rerio)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Sus scrofa)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Bos taurus)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Canis familiaris)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Rattus norvegicus)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Mus musculus)
IL20:IL20RA:JAK1:IL20RB:JAK2,JAK3 phosphorylates JAK2,JAK3 (Homo sapiens)
IL20:IL20RA:JAK1:IL20RB:p-JAK3,p-JAK2:STAT3 phosphorylates STAT3 (Homo sapiens)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Gallus gallus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Xenopus tropicalis)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Sus scrofa)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Bos taurus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Canis familiaris)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Rattus norvegicus)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Mus musculus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Gallus gallus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Bos taurus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Rattus norvegicus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
IFNL1:IFNLR1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Homo sapiens)
IFNL1:IFNLR1:p-JAK1:IL10RB:p-TYK2 phosphorylates IFNLR1 (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Gallus gallus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Danio rerio)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Sus scrofa)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Bos taurus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Canis familiaris)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Rattus norvegicus)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Mus musculus)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Gallus gallus)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Danio rerio)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Sus scrofa)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Bos taurus)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Canis familiaris)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Rattus norvegicus)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Mus musculus)
JAK1 in IL24:IL20RA:JAK1:IL20RB is phosphorylated (Homo sapiens)
IL24:IL20RA:p-JAK1:IL20RB:STAT1,STAT3 phosphorylates STAT1 or STAT3 (Homo sapiens)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Gallus gallus)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Sus scrofa)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Bos taurus)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Canis familiaris)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Rattus norvegicus)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Mus musculus)
STAT3 is phosphorylated by TSLP:IL7R:CRLF2:STAT3 complex (Homo sapiens)
NIK autophosphorylates on T559 (Saccharomyces cerevisiae)
NIK autophosphorylates on T559 (Gallus gallus)
NIK autophosphorylates on T559 (Xenopus tropicalis)
NIK autophosphorylates on T559 (Sus scrofa)
NIK autophosphorylates on T559 (Bos taurus)
NIK autophosphorylates on T559 (Canis familiaris)
NIK autophosphorylates on T559 (Rattus norvegicus)
NIK autophosphorylates on T559 (Mus musculus)
NIK autophosphorylates on T559 (Homo sapiens)
JAK2 phosphorylation of Irs-1/2 (Rattus norvegicus)
JAK2 phosphorylation of IRS-1/2 (Homo sapiens)
Jak2 phosphorylates Stat1/Stat3 (Mus musculus)
JAK2 phosphorylates STAT1/STAT3 (Homo sapiens)
Stat5 tyrosine phosphorylation (Mus musculus)
STAT5 tyrosine phosphorylation (Homo sapiens)
Lyn activates ERK (Gallus gallus)
Lyn activates ERK (Danio rerio)
Lyn activates ERK (Sus scrofa)
Lyn activates ERK (Bos taurus)
Lyn activates ERK (Canis familiaris)
Lyn activates ERK (Rattus norvegicus)
Lyn activates ERK (Mus musculus)
Lyn activates ERK (Homo sapiens)
JAK2 phosphorylation of GHR (Gallus gallus)
JAK2 phosphorylation of GHR (Danio rerio)
JAK2 phosphorylation of GHR (Rattus norvegicus)
JAK2 phosphorylation of GHR (Mus musculus)
JAK2 phosphorylation of GHR (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-JAK2:p-TYK2 binds and phosphorylates SHC1, GRB2, GAB2, and PTPN11 (SHP2) (Homo sapiens)
p-Y-Jak1,2 phosphorylates Stat1,3,5 in Csf3 dimer:2xp-4Y-Csf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2:Stat1,3,5 (Mus musculus)
p-Y-Jak1 phosphorylates Csf3r in Csf3 dimer:2xCsf3r:Lyn:p-Y-Jak1:p-Jak2:p-Tyk2 (Mus musculus)
p-Y-JAK1 phosphorylates CSF3R in CSF3 dimer:2xCSF3R:LYN:p-Y-JAK1 (Homo sapiens)
CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1 binds and activates JAK2, TYK2, SYK, and HCK (Homo sapiens)
p-Y-JAK1,2 phosphorylates STAT1,3,5 in CSF3 dimer:2xp-4Y-CSF3R:LYN:p-Y-JAK1:p-Y-JAK2:p-TYK2 (Homo sapiens)
Csf3:Csf3r induces phosphorylation of Jak1 (Mus musculus)
CSF3 dimer:2xCSF3R:LYN:JAK1 induces phosphorylation of JAK1 (Homo sapiens)
Syk/Lck phosphorylate LAT (Sus scrofa)
Syk/Lck phosphorylate LAT (Bos taurus)
Syk/Lck phosphorylate LAT (Canis familiaris)
Syk/Lck phosphorylate LAT (Rattus norvegicus)
Syk/Lck phosphorylate LAT (Mus musculus)
Syk/Lck phosphorylate LAT (Homo sapiens)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Sus scrofa)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Bos taurus)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Canis familiaris)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Rattus norvegicus)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Mus musculus)
Unknown kinase phosphorylates CLEC1B dimer:PDPN (Homo sapiens)
SYK activation by SRC (Caenorhabditis elegans)
SYK activation by SRC (Drosophila melanogaster)
SYK activation by SRC (Gallus gallus)
SYK activation by SRC (Sus scrofa)
SYK activation by SRC (Bos taurus)
SYK activation by SRC (Canis familiaris)
SYK activation by SRC (Rattus norvegicus)
SYK activation by SRC (Mus musculus)
SYK activation by SRC (Homo sapiens)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Gallus gallus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Sus scrofa)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Bos taurus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Canis familiaris)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Rattus norvegicus)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Mus musculus)
Phosphorylation of pPTK2 by SRC (Caenorhabditis elegans)
Phosphorylation of pPTK2 by SRC (Gallus gallus)
Phosphorylation of pPTK2 by SRC (Sus scrofa)
Phosphorylation of pPTK2 by SRC (Bos taurus)
Phosphorylation of pPTK2 by SRC (Canis familiaris)
Phosphorylation of pPTK2 by SRC (Rattus norvegicus)
Phosphorylation of pPTK2 by SRC (Mus musculus)
Autophosphorylation of PTK2 at Y397 (Caenorhabditis elegans)
Autophosphorylation of PTK2 at Y397 (Gallus gallus)
Autophosphorylation of PTK2 at Y397 (Sus scrofa)
Autophosphorylation of PTK2 at Y397 (Bos taurus)
Autophosphorylation of PTK2 at Y397 (Canis familiaris)
Autophosphorylation of PTK2 at Y397 (Rattus norvegicus)
Autophosphorylation of PTK2 at Y397 (Mus musculus)
Autophosphorylation of SRC (Caenorhabditis elegans)
Autophosphorylation of SRC (Drosophila melanogaster)
Autophosphorylation of SRC (Gallus gallus)
Autophosphorylation of SRC (Danio rerio)
Autophosphorylation of SRC (Sus scrofa)
Autophosphorylation of SRC (Bos taurus)
Autophosphorylation of SRC (Canis familiaris)
Autophosphorylation of SRC (Rattus norvegicus)
Autophosphorylation of SRC (Mus musculus)
Autophosphorylation of SRC (Homo sapiens)
Autophosphorylation of PTK2 at Y397 (Homo sapiens)
Phosphorylation of pPTK2 by SRC (Homo sapiens)
Phosphorylation of BCAR1 by SRC-PTK2 complex (Homo sapiens)
Phosphorylation of Syntaxin-4 (Saccharomyces cerevisiae)
Phosphorylation of Syntaxin-4 (Schizosaccharomyces pombe)
Phosphorylation of Syntaxin-4 (Dictyostelium discoideum)
Phosphorylation of Syntaxin-4 (Caenorhabditis elegans)
Phosphorylation of Syntaxin-4 (Drosophila melanogaster)
Phosphorylation of Syntaxin-4 (Xenopus tropicalis)
Phosphorylation of Syntaxin-4 (Danio rerio)
Phosphorylation of Syntaxin-4 (Sus scrofa)
Phosphorylation of Syntaxin-4 (Bos taurus)
Phosphorylation of Syntaxin-4 (Canis familiaris)
Phosphorylation of Syntaxin-4 (Rattus norvegicus)
Phosphorylation of Syntaxin-4 (Mus musculus)
Phosphorylation of Syntaxin-4 (Homo sapiens)
Phosphorylation of Platelet Sec-1 (Saccharomyces cerevisiae)
Phosphorylation of Platelet Sec-1 (Schizosaccharomyces pombe)
Phosphorylation of Platelet Sec-1 (Dictyostelium discoideum)
Phosphorylation of Platelet Sec-1 (Caenorhabditis elegans)
Phosphorylation of Platelet Sec-1 (Drosophila melanogaster)
Phosphorylation of Platelet Sec-1 (Gallus gallus)
Phosphorylation of Platelet Sec-1 (Xenopus tropicalis)
Phosphorylation of Platelet Sec-1 (Sus scrofa)
Phosphorylation of Platelet Sec-1 (Bos taurus)
Phosphorylation of Platelet Sec-1 (Canis familiaris)
Phosphorylation of Platelet Sec-1 (Rattus norvegicus)
Phosphorylation of Platelet Sec-1 (Mus musculus)
Phosphorylation of Platelet Sec-1 (Homo sapiens)
Kinesins move along microtubules consuming ATP (Caenorhabditis elegans)
Kinesins move along microtubules consuming ATP (Drosophila melanogaster)
Kinesins move along microtubules consuming ATP (Gallus gallus)
Kinesins move along microtubules consuming ATP (Xenopus tropicalis)
Kinesins move along microtubules consuming ATP (Sus scrofa)
Kinesins move along microtubules consuming ATP (Bos taurus)
Kinesins move along microtubules consuming ATP (Canis familiaris)
Kinesins move along microtubules consuming ATP (Rattus norvegicus)
Kinesins move along microtubules consuming ATP (Mus musculus)
Kinesins move along microtubules consuming ATP (Homo sapiens)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Dictyostelium discoideum)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Gallus gallus)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Xenopus tropicalis)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Danio rerio)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Sus scrofa)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Bos taurus)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Canis familiaris)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Rattus norvegicus)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Mus musculus)
ITPK1 converts Ins-3,4,5,6-P4 to Ins-1,3,4,5,6-P5 (Homo sapiens)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Dictyostelium discoideum)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Gallus gallus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Xenopus tropicalis)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Danio rerio)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Sus scrofa)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Canis familiaris)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Rattus norvegicus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Mus musculus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,5-P4 (Homo sapiens)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Dictyostelium discoideum)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Gallus gallus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Xenopus tropicalis)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Danio rerio)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Sus scrofa)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Bos taurus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Canis familiaris)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Rattus norvegicus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Mus musculus)
ITPK1 converts Ins-1,3,4-P3 to Ins-1,3,4,6-P4 (Homo sapiens)
ABCG2 transports Cipro from intestinal cell to extracellular space (Plasmodium falciparum)
ABCG2 transports Cipro from intestinal cell to extracellular space (Saccharomyces cerevisiae)
ABCG2 transports Cipro from intestinal cell to extracellular space (Dictyostelium discoideum)
ABCG2 transports Cipro from intestinal cell to extracellular space (Caenorhabditis elegans)
ABCG2 transports Cipro from intestinal cell to extracellular space (Drosophila melanogaster)
ABCG2 transports Cipro from intestinal cell to extracellular space (Xenopus tropicalis)
ABCG2 transports Cipro from intestinal cell to extracellular space (Sus scrofa)
ABCG2 transports Cipro from intestinal cell to extracellular space (Bos taurus)
ABCG2 transports Cipro from intestinal cell to extracellular space (Canis familiaris)
ABCG2 transports Cipro from intestinal cell to extracellular space (Rattus norvegicus)
ABCG2 transports Cipro from intestinal cell to extracellular space (Mus musculus)
ABCG2 transports Cipro from intestinal cell to extracellular space (Homo sapiens)
ABCG2 transports Cipro from hepatic cell to extracellular space (Plasmodium falciparum)
ABCG2 transports Cipro from hepatic cell to extracellular space (Saccharomyces cerevisiae)
ABCG2 transports Cipro from hepatic cell to extracellular space (Dictyostelium discoideum)
ABCG2 transports Cipro from hepatic cell to extracellular space (Caenorhabditis elegans)
ABCG2 transports Cipro from hepatic cell to extracellular space (Drosophila melanogaster)
ABCG2 transports Cipro from hepatic cell to extracellular space (Xenopus tropicalis)
ABCG2 transports Cipro from hepatic cell to extracellular space (Sus scrofa)
ABCG2 transports Cipro from hepatic cell to extracellular space (Bos taurus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Canis familiaris)
ABCG2 transports Cipro from hepatic cell to extracellular space (Rattus norvegicus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Mus musculus)
ABCG2 transports Cipro from hepatic cell to extracellular space (Homo sapiens)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Plasmodium falciparum)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Saccharomyces cerevisiae)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Schizosaccharomyces pombe)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Dictyostelium discoideum)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Caenorhabditis elegans)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Drosophila melanogaster)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Gallus gallus)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Danio rerio)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Sus scrofa)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Bos taurus)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Canis familiaris)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Rattus norvegicus)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Mus musculus)
NME1:2 hexamer phosphorylates 6TGDP to 6TGTP (Homo sapiens)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Plasmodium falciparum)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Saccharomyces cerevisiae)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Schizosaccharomyces pombe)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Dictyostelium discoideum)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Caenorhabditis elegans)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Drosophila melanogaster)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Danio rerio)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Plasmodium falciparum)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Saccharomyces cerevisiae)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Schizosaccharomyces pombe)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Dictyostelium discoideum)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Caenorhabditis elegans)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Drosophila melanogaster)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Gallus gallus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Gallus gallus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Xenopus tropicalis)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Danio rerio)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Sus scrofa)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Sus scrofa)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Bos taurus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Bos taurus)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Canis familiaris)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Canis familiaris)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Rattus norvegicus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Rattus norvegicus)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Mus musculus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Mus musculus)
GUK1 phosphorylates 6TdGMP to 6TdGDP (Homo sapiens)
NME1:2 hexamer phosphorylates 6TdGDP to 6TdGTP (Homo sapiens)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Caenorhabditis elegans)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Xenopus tropicalis)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Danio rerio)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Bos taurus)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Rattus norvegicus)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Mus musculus)
ABCC5 transports TPMP substrates from cytosol to extracellular region (Homo sapiens)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Plasmodium falciparum)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Dictyostelium discoideum)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Caenorhabditis elegans)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Drosophila melanogaster)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Gallus gallus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Danio rerio)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Sus scrofa)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Bos taurus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Canis familiaris)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Rattus norvegicus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Mus musculus)
ABCC4 transports TPMP substrates from cytosol to extracellular region (Homo sapiens)
GUK1 phosphorylates 6TGMP to 6TGDP (Plasmodium falciparum)
GUK1 phosphorylates 6TGMP to 6TGDP (Saccharomyces cerevisiae)
GUK1 phosphorylates 6TGMP to 6TGDP (Schizosaccharomyces pombe)
GUK1 phosphorylates 6TGMP to 6TGDP (Dictyostelium discoideum)
GUK1 phosphorylates 6TGMP to 6TGDP (Caenorhabditis elegans)
GUK1 phosphorylates 6TGMP to 6TGDP (Drosophila melanogaster)
GUK1 phosphorylates 6TGMP to 6TGDP (Gallus gallus)
GUK1 phosphorylates 6TGMP to 6TGDP (Xenopus tropicalis)
GUK1 phosphorylates 6TGMP to 6TGDP (Danio rerio)
GUK1 phosphorylates 6TGMP to 6TGDP (Sus scrofa)
GUK1 phosphorylates 6TGMP to 6TGDP (Bos taurus)
GUK1 phosphorylates 6TGMP to 6TGDP (Canis familiaris)
GUK1 phosphorylates 6TGMP to 6TGDP (Rattus norvegicus)
GUK1 phosphorylates 6TGMP to 6TGDP (Mus musculus)
GUK1 phosphorylates 6TGMP to 6TGDP (Homo sapiens)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Saccharomyces cerevisiae)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Schizosaccharomyces pombe)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Dictyostelium discoideum)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Caenorhabditis elegans)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Drosophila melanogaster)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Gallus gallus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Xenopus tropicalis)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Danio rerio)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Sus scrofa)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Bos taurus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Canis familiaris)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Rattus norvegicus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Mus musculus)
ABCC2, ABCC3 transport salicylate metabolites from cytosol to extracellular region of hepatic cells (Homo sapiens)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Schizosaccharomyces pombe)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Drosophila melanogaster)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Gallus gallus)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Xenopus tropicalis)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Danio rerio)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Sus scrofa)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Bos taurus)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Canis familiaris)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Mus musculus)
ABCC3,ABCC4 transport APAP-GlcA, APAP-SO3 (Homo sapiens)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Plasmodium falciparum)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Schizosaccharomyces pombe)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Dictyostelium discoideum)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Caenorhabditis elegans)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Drosophila melanogaster)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Gallus gallus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Xenopus tropicalis)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Danio rerio)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Sus scrofa)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Bos taurus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Canis familiaris)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Rattus norvegicus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Mus musculus)
ABCC1,4,5 transport APAP-Cys,APAP-Mer from cytosol to extracellular region (Homo sapiens)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Plasmodium falciparum)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Saccharomyces cerevisiae)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Schizosaccharomyces pombe)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Dictyostelium discoideum)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Caenorhabditis elegans)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Drosophila melanogaster)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Gallus gallus)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Xenopus tropicalis)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Danio rerio)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Sus scrofa)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Bos taurus)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Canis familiaris)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Rattus norvegicus)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Mus musculus)
ABCC2,ABCG2 transport APAP-GlcA, APAP-SO3 (Homo sapiens)
NME1,2 hexamers phosphorylate RBV-DP (Plasmodium falciparum)
NME1,2 hexamers phosphorylate RBV-DP (Saccharomyces cerevisiae)
NME1,2 hexamers phosphorylate RBV-DP (Schizosaccharomyces pombe)
NME1,2 hexamers phosphorylate RBV-DP (Dictyostelium discoideum)
NME1,2 hexamers phosphorylate RBV-DP (Caenorhabditis elegans)
NME1,2 hexamers phosphorylate RBV-DP (Drosophila melanogaster)
NME1,2 hexamers phosphorylate RBV-DP (Gallus gallus)
NME1,2 hexamers phosphorylate RBV-DP (Xenopus tropicalis)
NME1,2 hexamers phosphorylate RBV-DP (Danio rerio)
NME1,2 hexamers phosphorylate RBV-DP (Sus scrofa)
NME1,2 hexamers phosphorylate RBV-DP (Bos taurus)
NME1,2 hexamers phosphorylate RBV-DP (Canis familiaris)
NME1,2 hexamers phosphorylate RBV-DP (Rattus norvegicus)
NME1,2 hexamers phosphorylate RBV-DP (Mus musculus)
ADK phosphorylates RBV (Saccharomyces cerevisiae)
ADK phosphorylates RBV (Schizosaccharomyces pombe)
ADK phosphorylates RBV (Dictyostelium discoideum)
ADK phosphorylates RBV (Caenorhabditis elegans)
ADK phosphorylates RBV (Drosophila melanogaster)
ADK phosphorylates RBV (Gallus gallus)
ADK phosphorylates RBV (Xenopus tropicalis)
ADK phosphorylates RBV (Danio rerio)
ADK phosphorylates RBV (Sus scrofa)
ADK phosphorylates RBV (Bos taurus)
ADK phosphorylates RBV (Canis familiaris)
ADK phosphorylates RBV (Rattus norvegicus)
ADK phosphorylates RBV (Mus musculus)
ADK phosphorylates RBV (Homo sapiens)
Unknown kinase phosphorylates RBV-MP (Homo sapiens)
NME1,2 hexamers phosphorylate RBV-DP (Homo sapiens)
ABCB1 transports xenobiotics out of the cell (Plasmodium falciparum)
ABCB1 transports xenobiotics out of the cell (Schizosaccharomyces pombe)
ABCB1 transports xenobiotics out of the cell (Dictyostelium discoideum)
ABCB1 transports xenobiotics out of the cell (Gallus gallus)
ABCB1 transports xenobiotics out of the cell (Sus scrofa)
ABCB1 transports xenobiotics out of the cell (Bos taurus)
ABCB1 transports xenobiotics out of the cell (Canis familiaris)
ABCB1 transports xenobiotics out of the cell (Rattus norvegicus)
ABCB1 transports xenobiotics out of the cell (Mus musculus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Plasmodium falciparum)
ABCB1 transports PREDN,PREDL out of hepatic cells (Schizosaccharomyces pombe)
ABCB1 transports PREDN,PREDL out of hepatic cells (Dictyostelium discoideum)
ABCB1 transports PREDN,PREDL out of hepatic cells (Gallus gallus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Sus scrofa)
ABCB1 transports PREDN,PREDL out of hepatic cells (Bos taurus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Canis familiaris)
ABCB1 transports PREDN,PREDL out of hepatic cells (Rattus norvegicus)
ABCB1 transports PREDN,PREDL out of hepatic cells (Mus musculus)
ABCB1 transports PREDN,PREDL out of kidney cells (Plasmodium falciparum)
ABCB1 transports PREDN,PREDL out of kidney cells (Schizosaccharomyces pombe)
ABCB1 transports PREDN,PREDL out of kidney cells (Dictyostelium discoideum)
ABCB1 transports PREDN,PREDL out of kidney cells (Gallus gallus)
ABCB1 transports PREDN,PREDL out of kidney cells (Sus scrofa)
ABCB1 transports PREDN,PREDL out of kidney cells (Bos taurus)
ABCB1 transports PREDN,PREDL out of kidney cells (Canis familiaris)
ABCB1 transports PREDN,PREDL out of kidney cells (Rattus norvegicus)
ABCB1 transports PREDN,PREDL out of kidney cells (Mus musculus)
ABCB1 transports PREDN,PREDL out of kidney cells (Homo sapiens)
ABCB1 transports PREDN,PREDL out of hepatic cells (Homo sapiens)
ABCB1 transports xenobiotics out of the cell (Homo sapiens)
Phosphorylation of pChREBP (Thr 653) at Ser(196) by PKA (Homo sapiens)
Protein kinase C, alpha type phosphorylates MARCKS (Gallus gallus)
Protein kinase C, alpha type phosphorylates MARCKS (Sus scrofa)
Protein kinase C, alpha type phosphorylates MARCKS (Canis familiaris)
Protein kinase C, alpha type phosphorylates MARCKS (Rattus norvegicus)
Protein kinase C, alpha type phosphorylates MARCKS (Mus musculus)
Protein kinase C, alpha type phosphorylates MARCKS (Homo sapiens)
Ivacaftor:CFTR G551D transports Cl- from cytosol to extracellular region (Homo sapiens)
VCP-catalyzed ATP hydrolysis promotes the translocation of CFTR F508del into the cytosol (Homo sapiens)
Cdk5:p25 phosphorylates Prdx2 (Mus musculus)
CDK5:p25 phosphorylates PRDX2 (Homo sapiens)
p25-bound CDK5 phosphorylates CDC25B (Homo sapiens)
Cdk5:p25 phosphorylates Prdx1 (Mus musculus)
CDK5:p25 phosphorylates PRDX1 (Homo sapiens)
p25-bound CDK5 phosphorylates CDC25C (Homo sapiens)
Cdk5:p25 phosphorylates FOXO3 (Homo sapiens)
CDK5:p25 phosphorylates FOXO3 (Homo sapiens)
Cdk5:p25 phosphorylates Golga2 (Mus musculus)
CDK5:p25 phosphorylates GOLGA2 (Homo sapiens)
PkCa/q phosphorylate Rgs9-1:Gn5b:R9s9bp (Bos taurus)
PRKCA/Q phosphorylate RGS9-1:GN5B:RGS9BP (Homo sapiens)
ABCB11 transports bile salts from cytosol to extracellular region (Plasmodium falciparum)
ABCB11 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)
ABCB11 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)
ABCB11 transports bile salts from cytosol to extracellular region (Gallus gallus)
ABCB11 transports bile salts from cytosol to extracellular region (Sus scrofa)
ABCB11 transports bile salts from cytosol to extracellular region (Bos taurus)
ABCB11 transports bile salts from cytosol to extracellular region (Canis familiaris)
ABCB11 transports bile salts from cytosol to extracellular region (Rattus norvegicus)
ABCB11 transports bile salts from cytosol to extracellular region (Mus musculus)
ABCB11 transports bile salts from cytosol to extracellular region (Homo sapiens)
RFK:Mg2+ phosphorylates RIB (Plasmodium falciparum)
RFK:Mg2+ phosphorylates RIB (Drosophila melanogaster)
RFK:Mg2+ phosphorylates RIB (Gallus gallus)
RFK:Mg2+ phosphorylates RIB (Xenopus tropicalis)
RFK:Mg2+ phosphorylates RIB (Saccharomyces cerevisiae)
RFK:Mg2+ phosphorylates RIB (Schizosaccharomyces pombe)
RFK:Mg2+ phosphorylates RIB (Caenorhabditis elegans)
RFK:Mg2+ phosphorylates RIB (Sus scrofa)
RFK:Mg2+ phosphorylates RIB (Bos taurus)
RFK:Mg2+ phosphorylates RIB (Canis familiaris)
RFK:Mg2+ phosphorylates RIB (Rattus norvegicus)
RFK:Mg2+ phosphorylates RIB (Mus musculus)
RFK:Mg2+ phosphorylates RIB (Homo sapiens)
DCAKD phosphorylates DP-CoA (Plasmodium falciparum)
DCAKD phosphorylates DP-CoA (Saccharomyces cerevisiae)
DCAKD phosphorylates DP-CoA (Schizosaccharomyces pombe)
DCAKD phosphorylates DP-CoA (Caenorhabditis elegans)
DCAKD phosphorylates DP-CoA (Drosophila melanogaster)
DCAKD phosphorylates DP-CoA (Gallus gallus)
DCAKD phosphorylates DP-CoA (Xenopus tropicalis)
DCAKD phosphorylates DP-CoA (Danio rerio)
DCAKD phosphorylates DP-CoA (Sus scrofa)
DCAKD phosphorylates DP-CoA (Bos taurus)
DCAKD phosphorylates DP-CoA (Canis familiaris)
DCAKD phosphorylates DP-CoA (Rattus norvegicus)
DCAKD phosphorylates DP-CoA (Mus musculus)
DCAKD phosphorylates DP-CoA (Homo sapiens)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Plasmodium falciparum)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Caenorhabditis elegans)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Drosophila melanogaster)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Gallus gallus)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Xenopus tropicalis)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Danio rerio)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Sus scrofa)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Bos taurus)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Canis familiaris)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Rattus norvegicus)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Mus musculus)
SLC25A42 exchanges cytosolic CoA-SH for mitochondrial matrix ADP (Homo sapiens)
COASY phosphorylates DP-CoA (Saccharomyces cerevisiae)
COASY phosphorylates DP-CoA (Schizosaccharomyces pombe)
COASY phosphorylates DP-CoA (Dictyostelium discoideum)
COASY phosphorylates DP-CoA (Caenorhabditis elegans)
COASY phosphorylates DP-CoA (Gallus gallus)
COASY phosphorylates DP-CoA (Xenopus tropicalis)
COASY phosphorylates DP-CoA (Danio rerio)
COASY phosphorylates DP-CoA (Sus scrofa)
COASY phosphorylates DP-CoA (Bos taurus)
COASY phosphorylates DP-CoA (Canis familiaris)
COASY phosphorylates DP-CoA (Rattus norvegicus)
COASY phosphorylates DP-CoA (Mus musculus)
PANK2 phosphorylates PanK (Drosophila melanogaster)
PANK2 phosphorylates PanK (Gallus gallus)
PANK2 phosphorylates PanK (Xenopus tropicalis)
PANK2 phosphorylates PanK (Sus scrofa)
PANK2 phosphorylates PanK (Bos taurus)
PANK2 phosphorylates PanK (Canis familiaris)
PANK2 phosphorylates PanK (Rattus norvegicus)
PANK2 phosphorylates PanK (Mus musculus)
PANK2 phosphorylates PanK (Homo sapiens)
PANK1/3 phosphorylate PanK (Drosophila melanogaster)
PANK1/3 phosphorylate PanK (Gallus gallus)
PANK1/3 phosphorylate PanK (Danio rerio)
PANK1/3 phosphorylate PanK (Sus scrofa)
PANK1/3 phosphorylate PanK (Bos taurus)
PANK1/3 phosphorylate PanK (Canis familiaris)
PANK1/3 phosphorylate PanK (Rattus norvegicus)
PANK1/3 phosphorylate PanK (Mus musculus)
PANK1/3 phosphorylate PanK (Homo sapiens)
COASY phosphorylates DP-CoA (Homo sapiens)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Plasmodium falciparum)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Saccharomyces cerevisiae)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Schizosaccharomyces pombe)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Caenorhabditis elegans)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Drosophila melanogaster)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Gallus gallus)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Xenopus tropicalis)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Danio rerio)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Sus scrofa)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Bos taurus)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Canis familiaris)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Rattus norvegicus)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Mus musculus)
MTHFS transforms 5-formyl-THFPG to 5,10-methenyl-THFPG (Homo sapiens)
2xPDKX:2xZn2+ phosphorylates PDX (Plasmodium falciparum)
2xPDKX:2xZn2+ phosphorylates PDX (Saccharomyces cerevisiae)
2xPDKX:2xZn2+ phosphorylates PDX (Schizosaccharomyces pombe)
2xPDKX:2xZn2+ phosphorylates PDX (Dictyostelium discoideum)
2xPDKX:2xZn2+ phosphorylates PDX (Caenorhabditis elegans)
2xPDKX:2xZn2+ phosphorylates PDX (Drosophila melanogaster)
2xPDKX:2xZn2+ phosphorylates PDX (Gallus gallus)
2xPDKX:2xZn2+ phosphorylates PDX (Xenopus tropicalis)
2xPDKX:2xZn2+ phosphorylates PDX (Danio rerio)
2xPDKX:2xZn2+ phosphorylates PDX (Sus scrofa)
2xPDKX:2xZn2+ phosphorylates PDX (Bos taurus)
2xPDKX:2xZn2+ phosphorylates PDX (Canis familiaris)
2xPDKX:2xZn2+ phosphorylates PDX (Rattus norvegicus)
2xPDKX:2xZn2+ phosphorylates PDX (Mus musculus)
2xPDKX:2xZn2+ phosphorylates PDX (Homo sapiens)
2xPDXK:2xZn2+ phosphorylates PXL (Plasmodium falciparum)
2xPDXK:2xZn2+ phosphorylates PXL (Saccharomyces cerevisiae)
2xPDXK:2xZn2+ phosphorylates PXL (Schizosaccharomyces pombe)
2xPDXK:2xZn2+ phosphorylates PXL (Dictyostelium discoideum)
2xPDXK:2xZn2+ phosphorylates PXL (Caenorhabditis elegans)
2xPDXK:2xZn2+ phosphorylates PXL (Drosophila melanogaster)
2xPDXK:2xZn2+ phosphorylates PXL (Gallus gallus)
2xPDXK:2xZn2+ phosphorylates PXL (Xenopus tropicalis)
2xPDXK:2xZn2+ phosphorylates PXL (Danio rerio)
2xPDXK:2xZn2+ phosphorylates PXL (Sus scrofa)
2xPDXK:2xZn2+ phosphorylates PXL (Bos taurus)
2xPDXK:2xZn2+ phosphorylates PXL (Canis familiaris)
2xPDXK:2xZn2+ phosphorylates PXL (Rattus norvegicus)
2xPDXK:2xZn2+ phosphorylates PXL (Mus musculus)
2xPDXK:2xZn2+ phosphorylates PXL (Homo sapiens)
2xPDXK:2xZn2+ phosphorylates PXA (Plasmodium falciparum)
2xPDXK:2xZn2+ phosphorylates PXA (Saccharomyces cerevisiae)
2xPDXK:2xZn2+ phosphorylates PXA (Schizosaccharomyces pombe)
2xPDXK:2xZn2+ phosphorylates PXA (Dictyostelium discoideum)
2xPDXK:2xZn2+ phosphorylates PXA (Caenorhabditis elegans)
2xPDXK:2xZn2+ phosphorylates PXA (Drosophila melanogaster)
2xPDXK:2xZn2+ phosphorylates PXA (Gallus gallus)
2xPDXK:2xZn2+ phosphorylates PXA (Xenopus tropicalis)
2xPDXK:2xZn2+ phosphorylates PXA (Danio rerio)
2xPDXK:2xZn2+ phosphorylates PXA (Sus scrofa)
2xPDXK:2xZn2+ phosphorylates PXA (Bos taurus)
2xPDXK:2xZn2+ phosphorylates PXA (Canis familiaris)
2xPDXK:2xZn2+ phosphorylates PXA (Rattus norvegicus)
2xPDXK:2xZn2+ phosphorylates PXA (Mus musculus)
2xPDXK:2xZn2+ phosphorylates PXA (Homo sapiens)
TDPK phosphorylates ThDP to ThTP (Homo sapiens)
NPM1-ALK-dependent TYK2 phosphorylation (Homo sapiens)
ALK mutants phosphorylate SHC1 (Homo sapiens)
TYK2-dependent STAT1 and STAT3 phosphorylation (Homo sapiens)
NPM1-ALK-dependent MAPK8,9 phosphorylation (Homo sapiens)
NPM1-ALK- and PI3K-dependent MDM2 phosphorylation (Homo sapiens)
ALK fusions phosphorylate IRS1 (Homo sapiens)
ALK fusions phosphorylate FRS (Homo sapiens)
ALK fusions phosphorylate PLCG1 (Homo sapiens)
ALK mutants phosphorylate STAT3 (Homo sapiens)
Autophosphorylation of point mutants of ALK (Homo sapiens)
Autophosphorylation of ALK fusions (Homo sapiens)
PI3K synthesizes PIP3 downstream of ALK mutants (Homo sapiens)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Gallus gallus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Xenopus tropicalis)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Sus scrofa)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Bos taurus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Canis familiaris)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Rattus norvegicus)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Mus musculus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Gallus gallus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Xenopus tropicalis)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Sus scrofa)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Bos taurus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Canis familiaris)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Rattus norvegicus)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Mus musculus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Gallus gallus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Xenopus tropicalis)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Sus scrofa)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Bos taurus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Canis familiaris)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Rattus norvegicus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Mus musculus)
IL22:IL22RA1:JAK1:IL10RB:TYK2 phosphorylates JAK1,TYK2 (Homo sapiens)
IL22:IL22RA1:p-JAK1:IL10RB:p-TYK2 phosphorylates IL22RA (Homo sapiens)
IL22:p-Y251,p-Y301-IL22RA1:p-JAK1:IL10RB:p-TYK2:STAT3 phosphorylates STAT3 (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Gallus gallus)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Sus scrofa)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Bos taurus)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Canis familiaris)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Rattus norvegicus)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Mus musculus)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Gallus gallus)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Danio rerio)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Sus scrofa)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Bos taurus)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Canis familiaris)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Rattus norvegicus)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Mus musculus)
IL19:IL20RA:JAK1:IL20RB phosphorylates JAK1 (Homo sapiens)
IL19:IL20RA:p-JAK1:IL20RB:STAT3 phosphorylates STAT3 (Homo sapiens)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Gallus gallus)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Xenopus tropicalis)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Sus scrofa)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Bos taurus)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Canis familiaris)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Rattus norvegicus)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Mus musculus)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Gallus gallus)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Xenopus tropicalis)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Danio rerio)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Sus scrofa)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Bos taurus)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Canis familiaris)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Rattus norvegicus)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Mus musculus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Gallus gallus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Xenopus tropicalis)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Danio rerio)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Sus scrofa)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Bos taurus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Canis familiaris)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Rattus norvegicus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Mus musculus)
JAK1,TYK2 phosphorylate JAK1,TYK2 (Homo sapiens)
p-Y-JAK1,p-Y-TYK2 phosphorylate IL10RA (Homo sapiens)
STAT3 is phosphorylated by p-Y-JAK1,P-Y-TYK2 (Homo sapiens)
Active ALK phosphorylates Src (Homo sapiens)
Active ALK phosphorylates SRC (Homo sapiens)
PI3K synthesizes PIP3 downstream of ALK (Caenorhabditis elegans)
PI3K synthesizes PIP3 downstream of ALK (Drosophila melanogaster)
PI3K synthesizes PIP3 downstream of ALK (Gallus gallus)
PI3K synthesizes PIP3 downstream of ALK (Xenopus tropicalis)
PI3K synthesizes PIP3 downstream of ALK (Danio rerio)
PI3K synthesizes PIP3 downstream of ALK (Sus scrofa)
PI3K synthesizes PIP3 downstream of ALK (Bos taurus)
PI3K synthesizes PIP3 downstream of ALK (Canis familiaris)
PI3K synthesizes PIP3 downstream of ALK (Rattus norvegicus)
PI3K synthesizes PIP3 downstream of ALK (Mus musculus)
PI3K synthesizes PIP3 downstream of ALK (Homo sapiens)
Active ALK phosphorylates PLCG1 (Gallus gallus)
Active ALK phosphorylates PLCG1 (Danio rerio)
Active ALK phosphorylates PLCG1 (Sus scrofa)
Active ALK phosphorylates PLCG1 (Bos taurus)
Active ALK phosphorylates PLCG1 (Canis familiaris)
Active ALK phosphorylates PLCG1 (Rattus norvegicus)
Active ALK phosphorylates PLCG1 (Mus musculus)
Active ALK phosphorylates PLCG1 (Homo sapiens)
Active ALK phosphorylates IRS1 (Gallus gallus)
Active ALK phosphorylates IRS1 (Sus scrofa)
Active ALK phosphorylates IRS1 (Bos taurus)
Active ALK phosphorylates IRS1 (Canis familiaris)
Active ALK phosphorylates IRS1 (Rattus norvegicus)
Active ALK phosphorylates IRS1 (Mus musculus)
Active ALK phosphorylates IRS1 (Homo sapiens)
Active ALK phosphorylates SHC1 (Gallus gallus)
Active ALK phosphorylates SHC1 (Sus scrofa)
Active ALK phosphorylates SHC1 (Bos taurus)
Active ALK phosphorylates SHC1 (Canis familiaris)
Active ALK phosphorylates SHC1 (Rattus norvegicus)
Active ALK phosphorylates SHC1 (Mus musculus)
Active ALK phosphorylates SHC1 (Homo sapiens)
Active ALK phosphorylates JAK3 (Sus scrofa)
Active ALK phosphorylates JAK3 (Bos taurus)
Active ALK phosphorylates JAK3 (Canis familiaris)
Active ALK phosphorylates JAK3 (Rattus norvegicus)
Active ALK phosphorylates JAK3 (Mus musculus)
Active ALK phosphorylates JAK3 (Homo sapiens)
p-7Y ALK dimer phosphorylates Frs2 (Homo sapiens)
Active ALK phosphorylates FRS2 (Homo sapiens)
ALK autophosphorylation (Gallus gallus)
ALK autophosphorylation (Danio rerio)
ALK autophosphorylation (Sus scrofa)
ALK autophosphorylation (Bos taurus)
ALK autophosphorylation (Canis familiaris)
ALK autophosphorylation (Rattus norvegicus)
ALK autophosphorylation (Mus musculus)
ALK autophosphorylation (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to phosphorylated EGFRvIII (Homo sapiens)
Phosphorylation of PLC-gamma 1 by p-EGFRvIII mutant (Homo sapiens)
Phosphorylation of SHC1 by p-5Y-EGFRvIII (Homo sapiens)
Phosphorylation of CBL by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Phosphorylation of SHC1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Phosphorylation of PLCG1 by ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Conversion of PIP2 to PIP3 by PI3K bound to ligand-responsive p-6Y-EGFR mutants (Homo sapiens)
Trans-autophosphorylation of EGFRvIII mutant dimers (Homo sapiens)
Trans-autophosphorylation of activated ligand-responsive EGFR mutant dimers (Homo sapiens)
Autophosphorylation of membrane-tethered fusions of PDGFRA or PDGFRB (Homo sapiens)
PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of PDGFRA extracellular domain dimers (Homo sapiens)
Autophosphorylation of PDGFRA extracellular domain dimers (Homo sapiens)
Autophosphorylation of cytosolic PDGFRA and PDGFRB fusion proteins (Homo sapiens)
Autophosphorylation of PDGFR mutant dimers (Homo sapiens)
PI3K catalyses the phosphorylation of PIP2 to PIP3 downstream of mutant PDGFR (Homo sapiens)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Drosophila melanogaster)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Xenopus tropicalis)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Danio rerio)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Bos taurus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Canis familiaris)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Homo sapiens)
Hh processing variants are translocated to the cytosol in a VCP-dependent manner (Homo sapiens)
PI3K gain of function mutants phosphorylate PIP2 to PIP3 (Homo sapiens)
AKT1 E17K mutant phosphorylates GSK3 (Homo sapiens)
AKT1 E17K mutant phosphorylates caspase-9 (Homo sapiens)
AKT1 E17K mutant phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
AKT1 E17K mutant phosphorylates TSC2, inhibiting it (Homo sapiens)
AKT1 E17K mutant phosphorylates MDM2 (Homo sapiens)
AKT1 E17K mutant phosphorylates CHUK (IKKalpha) (Homo sapiens)
AKT1 E17K mutant phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
PDPK1 phosphorylates AKT1 E17K mutant (Homo sapiens)
AKT1 E17K mutant phosphorylates BAD (Homo sapiens)
AKT1 E17K mutant is phosphorylated by TORC2 complex (Homo sapiens)
Active LTK receptor phosphorylates SHC1 (Gallus gallus)
Active LTK receptor phosphorylates SHC1 (Xenopus tropicalis)
Active LTK receptor phosphorylates SHC1 (Rattus norvegicus)
Active LTK receptor phosphorylates SHC1 (Mus musculus)
Active LTK receptor phosphorylates SHC1 (Homo sapiens)
Active LTK phosphorylates IRS1 (Gallus gallus)
Active LTK phosphorylates IRS1 (Xenopus tropicalis)
Active LTK phosphorylates IRS1 (Rattus norvegicus)
Active LTK phosphorylates IRS1 (Mus musculus)
Active LTK phosphorylates IRS1 (Homo sapiens)
Autophosphorylation of LTK dimer:ALKAL1,2 (Gallus gallus)
Autophosphorylation of LTK dimer:ALKAL1,2 (Xenopus tropicalis)
Autophosphorylation of LTK dimer:ALKAL1,2 (Danio rerio)
Autophosphorylation of LTK dimer:ALKAL1,2 (Rattus norvegicus)
Autophosphorylation of LTK dimer:ALKAL1,2 (Mus musculus)
Autophosphorylation of LTK dimer:ALKAL1,2 (Homo sapiens)
CLIP1-LTK promotes MAPK1 and MAPK3 phosphorylation (Homo sapiens)
CLIP1-LTK fusion autophosphorylates (Homo sapiens)
Trans-autophosphorylation of ERBB2 homodimer (Homo sapiens)
ERBB2 homodimer phosphorylates SHC1 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 ECD mutants and EGFR phosphorylate SHC1 (Homo sapiens)
Heterodimers of ERBB2 ECD mutants and EGFR trans-autophosphorylate (Homo sapiens)
PI3K bound to phosphorylated heterodimers of ERBB2 ECD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and EGFR converts PIP2 to PIP3 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
PI3K bound to phosphorylated heterodimers of ERBB2 KD mutants and ERBB3 converts PIP2 to PIP3 (Homo sapiens)
Phosphorylated heterodimers of ERBB2 KD mutants phosphorylate SHC1 (Homo sapiens)
ERBB2 KD mutants trans-autophosphorylate (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants and EGFR phosphorylate PLCG1 (Homo sapiens)
ERBB2 TMD/JMD heterodimers trans-autophosphorylate (Homo sapiens)
Phosphorylated heterodimers of ERBB2 TMD/JMD mutants phosphorylate SHC1 (Homo sapiens)
FLT3 fusions phosphorylate GAB2 (Homo sapiens)
FLT3 fusion dimers autophosphorylate (Homo sapiens)
FLT3 phosphorylates GRB10 (Sus scrofa)
FLT3 phosphorylates GRB10 (Bos taurus)
FLT3 phosphorylates GRB10 (Canis familiaris)
FLT3 phosphorylates GRB10 (Mus musculus)
FLT3 phosphorylates GRB10 (Homo sapiens)
Active FLT3 phosphorylates CDKN1B (Sus scrofa)
Active FLT3 phosphorylates CDKN1B (Bos taurus)
Active FLT3 phosphorylates CDKN1B (Canis familiaris)
Active FLT3 phosphorylates CDKN1B (Mus musculus)
Active FLT3 phosphorylates CDKN1B (Homo sapiens)
FLT3 phosphorylates CBL (Sus scrofa)
FLT3 phosphorylates CBL (Bos taurus)
FLT3 phosphorylates CBL (Canis familiaris)
FLT3 phosphorylates CBL (Mus musculus)
FLT3 phosphorylates CBL (Homo sapiens)
FLT3 ITD mutants phosphorylate STAT5 (Homo sapiens)
Activator phosphorylates Stat5 (Mus musculus)
Activator phosphorylates STAT5 (Homo sapiens)
Constitutive phosphorylation of FLT3 mutants (Homo sapiens)
FLT3 mutants phosphorylate GAB2 (Homo sapiens)
Phosphorylation of extracellular domain KIT mutants (Homo sapiens)
Phosphorylation of STATs downstream of KIT mutants (Homo sapiens)
KIT mutants:PI3K catalyze synthesis of PIP3 (Homo sapiens)
Phosphorylation of juxtamembrane domain KIT mutants (Homo sapiens)
Constitutive phosphorylation of kinase domain KIT mutants (Homo sapiens)
Phosphorylation of JAK2 downstream of KIT mutants (Homo sapiens)
Activated FGFR4 mutants phosphorylate PLCG1 (Homo sapiens)
Activated FGFR4 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Autocatalytic phosphorylation of FGFR4 mutants with enhanced kinase activity (Homo sapiens)
Autocatalytic phosphorylation of FGFR4 Y367C mutant (Homo sapiens)
Activated FGFR4 mutants phosphorylate FRS2 (Homo sapiens)
Activated FGFR2 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Autocatalytic phosphorylation of overexpressed FGFR2 variants (Homo sapiens)
FGFR2 fusions autophosphorylate (Homo sapiens)
Autocatalytic phosphorylation of FGFR2b mutants with enhanced ligand binding (Homo sapiens)
Autocatalytic phosphorylation of FGFR2 ligand-independent mutants (Homo sapiens)
Autocatalytic phosphorylation of FGFR2 point mutants with enhanced kinase activity (Homo sapiens)
Autocatalytic phosphorylation of FGFR2c mutants with enhanced ligand binding (Homo sapiens)
Activated FGFR2 mutants phosphorylate PLCG1 (Homo sapiens)
Activated FGFR2 mutants phosphorylate FRS2 (Homo sapiens)
Activated FGFR3 point, translocation and fusion mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activated FGFR3 point and translocation mutants phosphorylate PLCG1 (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 cysteine mutants (Homo sapiens)
Autocatalytic phosphorylation of FGFR3c P250R mutant (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 point mutants with enhanced kinase activity (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 t(4;14) translocation mutants (Homo sapiens)
Autocatalytic phosphorylation of FGFR3 fusions (Homo sapiens)
Activated FGFR3 point, translocation and fusion mutants phosphorylate FRS2 (Homo sapiens)
Activated FGFR1 mutant-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Plasma membrane FGFR1 fusions autophosphorylate (Homo sapiens)
Autocatalytic phosphorylation of FGFR1 mutants with enhanced kinase activity (Homo sapiens)
Autocatalytic phosphorylation of FGFR1c P252X mutant dimers (Homo sapiens)
Ligand-independent phosphorylation of overexpressed FGFR1 (Homo sapiens)
Ligand-independent phosphorylation of overexpressed FGFR1c (Homo sapiens)
BCR-FGFR1-associated PI3K phosphorylates PIP2 to PIP3. (Homo sapiens)
FGFR1OP-FGFR1 phosphorylates STAT1 and STAT3 (Homo sapiens)
Phosphorylation of STAT5 by cytosolic FGFR1 fusions (Homo sapiens)
Cytosolic FGFR1 fusion protein-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Phosphorylation of BCR moiety of BCR-FGFR1 (Homo sapiens)
p-BCR-p-FGFR1 phosphorylates GAB2 (Homo sapiens)
Activated FGFR1 mutants phosphorylate FRS2 (Homo sapiens)
Phosphorylation of cytosolic FGFR1 fusion dimers (Homo sapiens)
Activated FGFR1 mutants and fusions phosphorylate PLCG1 (Homo sapiens)
GTP-bound RAC1 contributes to MAPK8 activation (Homo sapiens)
Unknown kinase phosphorylates p-DVL (Homo sapiens)
IgG:Leishmania surface:FCGR3A translocates from plasma membrane to the parasitophorous vacuole (Homo sapiens)
ALOX5 is phosphorylated by MAPKAP2 (Gallus gallus)
ALOX5 is phosphorylated by MAPKAP2 (Danio rerio)
ALOX5 is phosphorylated by MAPKAP2 (Sus scrofa)
ALOX5 is phosphorylated by MAPKAP2 (Bos taurus)
ALOX5 is phosphorylated by MAPKAP2 (Rattus norvegicus)
ALOX5 is phosphorylated by MAPKAP2 (Mus musculus)
ALOX5 is phosphorylated by MAPKAP2 (Homo sapiens)
PLK2, MAPK14 phosphorylate ADAM17 (Homo sapiens)
CK2 phosphorylates nascent P (Homo sapiens)
abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Mus musculus)
abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)
abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Mus musculus)
abacavir [cytosol] + ATP + H2O => abacavir[extracellular] + ADP + phosphate (Homo sapiens)
carbovir diphosphate + ATP => carbovir triphosphate + ADP (Rattus norvegicus)
carbovir monophosphate + ATP => carbovir diphosphate + ADP (Sus scrofa)
carbovir monophosphate + ATP => carbovir diphosphate + ADP (Homo sapiens)
carbovir diphosphate + ATP => carbovir triphosphate + ADP (Homo sapiens)
SRC autophosphorylation is positively regulated by InlA-bound CDH1 (Homo sapiens)
SRC phosphorylates InlA-bound CDH1 and CTNNB1 (Homo sapiens)
InlB-activated MET phosphorylates CBL (Homo sapiens)
InlB:MET dimer trans-autophophorylates (Homo sapiens)
FN3K phosphorylates ketosamines (Caenorhabditis elegans)
FN3K phosphorylates ketosamines (Gallus gallus)
FN3K phosphorylates ketosamines (Xenopus tropicalis)
FN3K phosphorylates ketosamines (Danio rerio)
FN3K phosphorylates ketosamines (Sus scrofa)
FN3K phosphorylates ketosamines (Canis familiaris)
FN3K phosphorylates ketosamines (Rattus norvegicus)
FN3K phosphorylates ketosamines (Mus musculus)
FN3K phosphorylates ketosamines (Homo sapiens)
FN3KRP phosphorylates PsiAm, RibAm (Caenorhabditis elegans)
FN3KRP phosphorylates PsiAm, RibAm (Gallus gallus)
FN3KRP phosphorylates PsiAm, RibAm (Xenopus tropicalis)
FN3KRP phosphorylates PsiAm, RibAm (Danio rerio)
FN3KRP phosphorylates PsiAm, RibAm (Sus scrofa)
FN3KRP phosphorylates PsiAm, RibAm (Bos taurus)
FN3KRP phosphorylates PsiAm, RibAm (Canis familiaris)
FN3KRP phosphorylates PsiAm, RibAm (Rattus norvegicus)
FN3KRP phosphorylates PsiAm, RibAm (Mus musculus)
FN3KRP phosphorylates PsiAm, RibAm (Homo sapiens)
MAPK-dependent phosphorylation of KARS (Dictyostelium discoideum)
MAPK-dependent phosphorylation of KARS (Drosophila melanogaster)
MAPK-dependent phosphorylation of KARS (Gallus gallus)
MAPK-dependent phosphorylation of KARS (Sus scrofa)
MAPK-dependent phosphorylation of KARS (Bos taurus)
MAPK-dependent phosphorylation of KARS (Canis familiaris)
MAPK-dependent phosphorylation of KARS (Rattus norvegicus)
MAPK-dependent phosphorylation of KARS (Mus musculus)
MAPK-dependent phosphorylation of KARS (Homo sapiens)
Akt2 Phosphorylates Myosin 5a (Mus musculus)
p-AKT2 phosphorylates Myosin 5A (Homo sapiens)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Gallus gallus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Sus scrofa)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Bos taurus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Canis familiaris)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Rattus norvegicus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Mus musculus)
FYN phosphorylates DAB1 in RELN:VLDLR:DAB1:SH3KBP1 (Homo sapiens)
Phosphorylation of PLCgamma by Netrin-1 (Rattus norvegicus)
Phosphorylation of PLCgamma by Netrin-1 (Homo sapiens)
Phosphorylation and activation of Ezrin (Caenorhabditis elegans)
Phosphorylation and activation of Ezrin (Drosophila melanogaster)
Phosphorylation and activation of Ezrin (Sus scrofa)
Phosphorylation and activation of Ezrin (Bos taurus)
Phosphorylation and activation of Ezrin (Canis familiaris)
Phosphorylation and activation of Ezrin (Rattus norvegicus)
Phosphorylation and activation of Ezrin (Mus musculus)
Phosphorylation and activation of Ezrin (Homo sapiens)
Phosphorylation of Unc5C (Mus musculus)
Phosphorylation of Unc5C (Homo sapiens)
PKA phosphorylates RET:GDNF:GFRA dimer (Sus scrofa)
PKA phosphorylates RET:GDNF:GFRA dimer (Bos taurus)
PKA phosphorylates RET:GDNF:GFRA dimer (Canis familiaris)
PKA phosphorylates RET:GDNF:GFRA dimer (Rattus norvegicus)
PKA phosphorylates RET:GDNF:GFRA dimer (Mus musculus)
PKA phosphorylates RET:GDNF:GFRA dimer (Homo sapiens)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Drosophila melanogaster)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Gallus gallus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Xenopus tropicalis)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Sus scrofa)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Bos taurus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Canis familiaris)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Rattus norvegicus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Mus musculus)
GAB in p-5Y-RET:GDNF:GFRA complexes is phosphorylated (Homo sapiens)
p-EPHB phosphorylates SDC2 (Caenorhabditis elegans)
p-EPHB phosphorylates SDC2 (Drosophila melanogaster)
p-EPHB phosphorylates SDC2 (Gallus gallus)
p-EPHB phosphorylates SDC2 (Xenopus tropicalis)
p-EPHB phosphorylates SDC2 (Danio rerio)
p-EPHB phosphorylates SDC2 (Sus scrofa)
p-EPHB phosphorylates SDC2 (Bos taurus)
p-EPHB phosphorylates SDC2 (Rattus norvegicus)
p-EPHB phosphorylates SDC2 (Mus musculus)
p-EPHB phosphorylates SDC2 (Homo sapiens)
PAK1 autophosphorylates (Dictyostelium discoideum)
PAK1 autophosphorylates (Caenorhabditis elegans)
PAK1 autophosphorylates (Drosophila melanogaster)
PAK1 autophosphorylates (Gallus gallus)
PAK1 autophosphorylates (Xenopus tropicalis)
PAK1 autophosphorylates (Sus scrofa)
PAK1 autophosphorylates (Bos taurus)
PAK1 autophosphorylates (Canis familiaris)
PAK1 autophosphorylates (Rattus norvegicus)
PAK1 autophosphorylates (Mus musculus)
PAK1 autophosphorylates (Homo sapiens)
EPHB phosphorylates TIAM1 (Caenorhabditis elegans)
EPHB phosphorylates TIAM1 (Drosophila melanogaster)
EPHB phosphorylates TIAM1 (Gallus gallus)
EPHB phosphorylates TIAM1 (Xenopus tropicalis)
EPHB phosphorylates TIAM1 (Sus scrofa)
EPHB phosphorylates TIAM1 (Canis familiaris)
EPHB phosphorylates TIAM1 (Rattus norvegicus)
EPHB phosphorylates TIAM1 (Mus musculus)
Fyn phosphorylates Nmdar2b (Mus musculus)
FYN phosphorylates NMDAR2B (Homo sapiens)
EPHB phosphorylates TIAM1 (Homo sapiens)
Activated ROCK phosphorylates MRLCs (Homo sapiens)
PAKs phosphorylate MLC (Caenorhabditis elegans)
PAKs phosphorylate MLC (Drosophila melanogaster)
PAKs phosphorylate MLC (Gallus gallus)
PAKs phosphorylate MLC (Xenopus tropicalis)
PAKs phosphorylate MLC (Sus scrofa)
PAKs phosphorylate MLC (Bos taurus)
PAKs phosphorylate MLC (Canis familiaris)
PAKs phosphorylate MLC (Rattus norvegicus)
PAKs phosphorylate MLC (Homo sapiens)
PAKs autophosphorylate (Caenorhabditis elegans)
PAKs autophosphorylate (Drosophila melanogaster)
PAKs autophosphorylate (Gallus gallus)
PAKs autophosphorylate (Xenopus tropicalis)
PAKs autophosphorylate (Sus scrofa)
PAKs autophosphorylate (Bos taurus)
PAKs autophosphorylate (Canis familiaris)
PAKs autophosphorylate (Rattus norvegicus)
PAKs autophosphorylate (Mus musculus)
PAKs autophosphorylate (Homo sapiens)
SFKs phosphorylate Git1 (Mus musculus)
Sfks phosphorylate EfnB1 (Gallus gallus)
SFKs phosphorylate EFNBs (Homo sapiens)
SFKs phosphorylate GIT1 (Homo sapiens)
EPH receptors autophosphorylate (Caenorhabditis elegans)
EPH receptors autophosphorylate (Drosophila melanogaster)
EPH receptors autophosphorylate (Gallus gallus)
EPH receptors autophosphorylate (Xenopus tropicalis)
EPH receptors autophosphorylate (Danio rerio)
EPH receptors autophosphorylate (Sus scrofa)
EPH receptors autophosphorylate (Bos taurus)
EPH receptors autophosphorylate (Canis familiaris)
EPH receptors autophosphorylate (Rattus norvegicus)
EPH receptors autophosphorylate (Mus musculus)
EPH receptors autophosphorylate (Homo sapiens)
SFKs phosphorylate VAV2,3 (Caenorhabditis elegans)
SFKs phosphorylate VAV2,3 (Drosophila melanogaster)
SFKs phosphorylate VAV2,3 (Gallus gallus)
SFKs phosphorylate VAV2,3 (Xenopus tropicalis)
SFKs phosphorylate VAV2,3 (Danio rerio)
SFKs phosphorylate VAV2,3 (Sus scrofa)
SFKs phosphorylate VAV2,3 (Bos taurus)
SFKs phosphorylate VAV2,3 (Canis familiaris)
SFKs phosphorylate VAV2,3 (Rattus norvegicus)
SFKs phosphorylate VAV2,3 (Mus musculus)
SFKs phosphorylate VAV2,3 (Homo sapiens)
Interaction of PAK1 with Rac1-GTP (Dictyostelium discoideum)
Interaction of PAK1 with Rac1-GTP (Caenorhabditis elegans)
Interaction of PAK1 with Rac1-GTP (Drosophila melanogaster)
Interaction of PAK1 with Rac1-GTP (Gallus gallus)
Interaction of PAK1 with Rac1-GTP (Xenopus tropicalis)
Interaction of PAK1 with Rac1-GTP (Sus scrofa)
Interaction of PAK1 with Rac1-GTP (Bos taurus)
Interaction of PAK1 with Rac1-GTP (Canis familiaris)
Interaction of PAK1 with Rac1-GTP (Rattus norvegicus)
Interaction of PAK1 with Rac1-GTP (Mus musculus)
Phosphorylation of VAV2 (Homo sapiens)
Interaction of PAK1 with Rac1-GTP (Homo sapiens)
Phosphorylation of L1 by CK-II (Caenorhabditis elegans)
Phosphorylation of L1 by CK-II (Rattus norvegicus)
Phosphorylation of L1 by CK-II (Mus musculus)
Phosphorylation of L1 by CK-II (Homo sapiens)
Phosphorylation of L1 by ERK (Saccharomyces cerevisiae)
Phosphorylation of L1 by ERK (Schizosaccharomyces pombe)
Phosphorylation of L1 by ERK (Dictyostelium discoideum)
Phosphorylation of L1 by ERK (Caenorhabditis elegans)
Phosphorylation of L1 by ERK (Drosophila melanogaster)
Phosphorylation of L1 by ERK (Gallus gallus)
Phosphorylation of L1 by ERK (Xenopus tropicalis)
Phosphorylation of L1 by ERK (Sus scrofa)
Phosphorylation of L1 by ERK (Bos taurus)
Phosphorylation of L1 by ERK (Canis familiaris)
Phosphorylation of L1 by ERK (Rattus norvegicus)
Phosphorylation of L1 by ERK (Mus musculus)
Phosphorylation of L1 by ERK (Homo sapiens)
Phosphorylation of L1 by p90rsk (Homo sapiens)
Phosphorylation of L1 by p90rsk (Homo sapiens)
Phosphorylation of L1 by SRC (Caenorhabditis elegans)
Phosphorylation of L1 by SRC (Rattus norvegicus)
Phosphorylation of L1 by SRC (Mus musculus)
Phosphorylation of L1 by SRC (Homo sapiens)
Phosphorylation of L1 by EPHB2 (Gallus gallus)
Phosphorylation of L1 by EPHB2 (Homo sapiens)
Phosphorylation of Neurofascin (Rattus norvegicus)
Phosphorylation of Neurofascin (Homo sapiens)
Phosphorylation of Y1229 in L1 (Homo sapiens)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Plasmodium falciparum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Saccharomyces cerevisiae)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Schizosaccharomyces pombe)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Dictyostelium discoideum)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Caenorhabditis elegans)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Drosophila melanogaster)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Gallus gallus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Xenopus tropicalis)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Danio rerio)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Sus scrofa)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Bos taurus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Canis familiaris)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Rattus norvegicus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Mus musculus)
SMG1 phosphorylates UPF1 (enhanced by Exon Junction Complex) (Homo sapiens)
Phosphorylation of ROBO1 by ABL kinase (Drosophila melanogaster)
Phosphorylation of ROBO1 by ABL kinase (Bos taurus)
Phosphorylation of ROBO1 by ABL kinase (Mus musculus)
Phosphorylation of ROBO1 by ABL kinase (Homo sapiens)
PKC phosphorylates ROBO3.1 (Canis familiaris)
PKC phosphorylates ROBO3.1 (Homo sapiens)
Src phosphorylates Robo3.1 in response to Ntn1 (Mus musculus)
SRC phosphorylates ROBO3.1 in response to NTN1 (Homo sapiens)
Activation of p38 alpha/beta MAPK (Mus musculus)
Activation of p38 alpha/beta MAPK (Homo sapiens)
CSNK1E,CSNK1D phosphorylate CRY and PER proteins (Homo sapiens)
IRE1 dimer autophosphorylates (Saccharomyces cerevisiae)
IRE1 dimer autophosphorylates (Schizosaccharomyces pombe)
IRE1 dimer autophosphorylates (Dictyostelium discoideum)
IRE1 dimer autophosphorylates (Caenorhabditis elegans)
IRE1 dimer autophosphorylates (Drosophila melanogaster)
IRE1 dimer autophosphorylates (Gallus gallus)
IRE1 dimer autophosphorylates (Xenopus tropicalis)
IRE1 dimer autophosphorylates (Bos taurus)
IRE1 dimer autophosphorylates (Canis familiaris)
IRE1 dimer autophosphorylates (Rattus norvegicus)
IRE1 dimer autophosphorylates (Mus musculus)
IRE1 dimer autophosphorylates (Homo sapiens)
Eif2ak3 phosphorylates Nfe2l2 (Mus musculus)
EIF2AK3 phosphorylates NFE2L2 (Homo sapiens)
Ptk6 phosphorylates Stat3 (Mus musculus)
PTK6 phosphorylates STAT3 (Homo sapiens)
GSS:Mg2+ dimer synthesizes GSH (Plasmodium falciparum)
GSS:Mg2+ dimer synthesizes GSH (Gallus gallus)
GSS:Mg2+ dimer synthesizes GSH (Saccharomyces cerevisiae)
OPLAH hydrolyses OPRO to L-Glu (Saccharomyces cerevisiae)
GCL ligates L-Glu to L-Cys (Schizosaccharomyces pombe)
GSS:Mg2+ dimer synthesizes GSH (Schizosaccharomyces pombe)
OPLAH hydrolyses OPRO to L-Glu (Schizosaccharomyces pombe)
GSS:Mg2+ dimer synthesizes GSH (Dictyostelium discoideum)
OPLAH hydrolyses OPRO to L-Glu (Dictyostelium discoideum)
GSS:Mg2+ dimer synthesizes GSH (Caenorhabditis elegans)
GCL ligates L-Glu to L-Cys (Caenorhabditis elegans)
OPLAH hydrolyses OPRO to L-Glu (Caenorhabditis elegans)
GSS:Mg2+ dimer synthesizes GSH (Drosophila melanogaster)
GCL ligates L-Glu to L-Cys (Drosophila melanogaster)
OPLAH hydrolyses OPRO to L-Glu (Drosophila melanogaster)
GCL ligates L-Glu to L-Cys (Xenopus tropicalis)
OPLAH hydrolyses OPRO to L-Glu (Xenopus tropicalis)
GSS:Mg2+ dimer synthesizes GSH (Danio rerio)
OPLAH hydrolyses OPRO to L-Glu (Danio rerio)
GCL ligates L-Glu to L-Cys (Sus scrofa)
GSS:Mg2+ dimer synthesizes GSH (Sus scrofa)
OPLAH hydrolyses OPRO to L-Glu (Sus scrofa)
GCL ligates L-Glu to L-Cys (Bos taurus)
GSS:Mg2+ dimer synthesizes GSH (Bos taurus)
OPLAH hydrolyses OPRO to L-Glu (Bos taurus)
GSS:Mg2+ dimer synthesizes GSH (Canis familiaris)
GCL ligates L-Glu to L-Cys (Canis familiaris)
OPLAH hydrolyses OPRO to L-Glu (Canis familiaris)
GCL ligates L-Glu to L-Cys (Rattus norvegicus)
GSS:Mg2+ dimer synthesizes GSH (Rattus norvegicus)
OPLAH hydrolyses OPRO to L-Glu (Rattus norvegicus)
OPLAH hydrolyses OPRO to L-Glu (Homo sapiens)
GCL ligates L-Glu to L-Cys (Homo sapiens)
OPLAH hydrolyses OPRO to L-Glu (Mus musculus)
GCL ligates L-Glu to L-Cys (Mus musculus)
GSS:Mg2+ dimer synthesizes GSH (Mus musculus)
GSS:Mg2+ dimer synthesizes GSH (Homo sapiens)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Plasmodium falciparum)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Saccharomyces cerevisiae)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Schizosaccharomyces pombe)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Caenorhabditis elegans)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Drosophila melanogaster)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Gallus gallus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Xenopus tropicalis)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Sus scrofa)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Bos taurus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Canis familiaris)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Rattus norvegicus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Mus musculus)
ATP2C1/2:Mg2+ transport cytosolic Ca2+ to Golgi lumen (Homo sapiens)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Plasmodium falciparum)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Saccharomyces cerevisiae)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Schizosaccharomyces pombe)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Dictyostelium discoideum)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Caenorhabditis elegans)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Drosophila melanogaster)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Gallus gallus)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Xenopus tropicalis)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Sus scrofa)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Bos taurus)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Canis familiaris)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Rattus norvegicus)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Mus musculus)
ATP13A1 transports Mn2+ from cytosol to ER lumen (Homo sapiens)
ATP13A2 transports cations from cytosol to lysosomal lumen (Plasmodium falciparum)
ATP13A2 transports cations from cytosol to lysosomal lumen (Saccharomyces cerevisiae)
ATP13A2 transports cations from cytosol to lysosomal lumen (Schizosaccharomyces pombe)
ATP13A2 transports cations from cytosol to lysosomal lumen (Dictyostelium discoideum)
ATP13A2 transports cations from cytosol to lysosomal lumen (Gallus gallus)
ATP13A2 transports cations from cytosol to lysosomal lumen (Xenopus tropicalis)
ATP13A2 transports cations from cytosol to lysosomal lumen (Danio rerio)
ATP13A2 transports cations from cytosol to lysosomal lumen (Sus scrofa)
ATP13A2 transports cations from cytosol to lysosomal lumen (Bos taurus)
ATP13A2 transports cations from cytosol to lysosomal lumen (Canis familiaris)
ATP13A2 transports cations from cytosol to lysosomal lumen (Rattus norvegicus)
ATP13A2 transports cations from cytosol to lysosomal lumen (Mus musculus)
ATP13A2 transports cations from cytosol to lysosomal lumen (Homo sapiens)
ATP12A:ATP4B exchanges K+ for H+ (Gallus gallus)
ATP12A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)
ATP12A:ATP4B exchanges K+ for H+ (Sus scrofa)
ATP12A:ATP4B exchanges K+ for H+ (Bos taurus)
ATP12A:ATP4B exchanges K+ for H+ (Canis familiaris)
ATP12A:ATP4B exchanges K+ for H+ (Rattus norvegicus)
ATP12A:ATP4B exchanges K+ for H+ (Mus musculus)
ATP12A:ATP4B exchanges K+ for H+ (Homo sapiens)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Plasmodium falciparum)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Saccharomyces cerevisiae)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Schizosaccharomyces pombe)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Dictyostelium discoideum)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Caenorhabditis elegans)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Drosophila melanogaster)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Gallus gallus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Xenopus tropicalis)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Canis familiaris)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Rattus norvegicus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Mus musculus)
ATP7B transports cytosolic Cu2+ to Golgi lumen (Homo sapiens)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Xenopus tropicalis)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Danio rerio)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Sus scrofa)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Canis familiaris)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Rattus norvegicus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Mus musculus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
ATP7A transports cytosolic Cu2+ to extracellular region (Gallus gallus)
ATP7A transports cytosolic Cu2+ to extracellular region (Xenopus tropicalis)
ATP7A transports cytosolic Cu2+ to extracellular region (Danio rerio)
ATP7A transports cytosolic Cu2+ to extracellular region (Sus scrofa)
ATP7A transports cytosolic Cu2+ to extracellular region (Canis familiaris)
ATP7A transports cytosolic Cu2+ to extracellular region (Rattus norvegicus)
ATP7A transports cytosolic Cu2+ to extracellular region (Mus musculus)
ATP7A transports cytosolic Cu2+ to extracellular region (Homo sapiens)
ATP4A:ATP4B exchanges K+ for H+ (Xenopus tropicalis)
ATP4A:ATP4B exchanges K+ for H+ (Sus scrofa)
ATP4A:ATP4B exchanges K+ for H+ (Bos taurus)
ATP4A:ATP4B exchanges K+ for H+ (Canis familiaris)
ATP4A:ATP4B exchanges K+ for H+ (Rattus norvegicus)
ATP4A:ATP4B exchanges K+ for H+ (Mus musculus)
ATP4A:ATP4B exchanges K+ for H+ (Homo sapiens)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Plasmodium falciparum)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Saccharomyces cerevisiae)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Schizosaccharomyces pombe)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Dictyostelium discoideum)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Caenorhabditis elegans)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Drosophila melanogaster)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Gallus gallus)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Xenopus tropicalis)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Danio rerio)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Sus scrofa)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Bos taurus)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Canis familiaris)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Rattus norvegicus)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Mus musculus)
P-type ATPases type IV transport internal-facing APLs to external side of the plasma membrane (Homo sapiens)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Plasmodium falciparum)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Saccharomyces cerevisiae)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Schizosaccharomyces pombe)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Dictyostelium discoideum)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Caenorhabditis elegans)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Drosophila melanogaster)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Gallus gallus)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Xenopus tropicalis)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Danio rerio)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Sus scrofa)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Bos taurus)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Canis familiaris)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Rattus norvegicus)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Mus musculus)
P-type ATPases type IV transport external-facing APLs to internal side of the plasma membrane (Homo sapiens)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Plasmodium falciparum)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Saccharomyces cerevisiae)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Schizosaccharomyces pombe)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Dictyostelium discoideum)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Caenorhabditis elegans)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Drosophila melanogaster)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Gallus gallus)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Xenopus tropicalis)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Sus scrofa)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Bos taurus)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Canis familiaris)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Rattus norvegicus)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Mus musculus)
ATP13A4,5 transport divalent ions from extracellular region to cytosol (Homo sapiens)
DMPK phosphorylates PLN (Sus scrofa)
DMPK phosphorylates PLN (Rattus norvegicus)
DMPK phosphorylates PLN (Mus musculus)
DMPK phosphorylates PLN (Homo sapiens)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Caenorhabditis elegans)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Gallus gallus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Canis familiaris)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Rattus norvegicus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Mus musculus)
RAF1:SGK:TSC22D3:WPP ubiquitinates SCNN channels (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Gallus gallus)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Danio rerio)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Sus scrofa)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Bos taurus)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Canis familiaris)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Mus musculus)
4xPALM-C-p-2S-ABCA1 tetramer transports PL from transport vesicle membrane to plasma membrane (Homo sapiens)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Caenorhabditis elegans)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Drosophila melanogaster)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Gallus gallus)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Xenopus tropicalis)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Danio rerio)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Sus scrofa)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Bos taurus)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Canis familiaris)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Rattus norvegicus)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Mus musculus)
PKA phosphorylates 4xPALM-C-p-2S-ABCA1 tetramer (Homo sapiens)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Gallus gallus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Danio rerio)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Sus scrofa)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Bos taurus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Canis familiaris)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Rattus norvegicus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Mus musculus)
4xPALM-C-p-2S-ABCA1 tetramer transports CHOL from transport vesicle membrane to plasma membrane (Homo sapiens)
ABCC3 transports bile salts from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCC3 transports bile salts from cytosol to extracellular region (Schizosaccharomyces pombe)
ABCC3 transports bile salts from cytosol to extracellular region (Dictyostelium discoideum)
ABCC3 transports bile salts from cytosol to extracellular region (Caenorhabditis elegans)
ABCC3 transports bile salts from cytosol to extracellular region (Drosophila melanogaster)
ABCC3 transports bile salts from cytosol to extracellular region (Gallus gallus)
ABCC3 transports bile salts from cytosol to extracellular region (Xenopus tropicalis)
ABCC3 transports bile salts from cytosol to extracellular region (Sus scrofa)
ABCC3 transports bile salts from cytosol to extracellular region (Bos taurus)
ABCC3 transports bile salts from cytosol to extracellular region (Canis familiaris)
ABCC3 transports bile salts from cytosol to extracellular region (Rattus norvegicus)
ABCC3 transports bile salts from cytosol to extracellular region (Mus musculus)
ABCC3 transports bile salts from cytosol to extracellular region (Homo sapiens)
ABCA4 mediates atRAL transport (Plasmodium falciparum)
ABCA4 mediates atRAL transport (Dictyostelium discoideum)
ABCA4 mediates atRAL transport (Caenorhabditis elegans)
ABCA4 mediates atRAL transport (Xenopus tropicalis)
GRK1,4,7 phosphorylate MII to p-MII (Caenorhabditis elegans)
GRK1,4,7 phosphorylate MII to p-MII (Gallus gallus)
GRK1,4,7 phosphorylate MII to p-MII (Danio rerio)
GRK1,4,7 phosphorylate MII to p-MII (Sus scrofa)
GRK1,4,7 phosphorylate MII to p-MII (Bos taurus)
GRK1,4,7 phosphorylate MII to p-MII (Canis familiaris)
GRK1,4,7 phosphorylate MII to p-MII (Rattus norvegicus)
GRK1,4,7 phosphorylate MII to p-MII (Mus musculus)
ABCA4 mediates atRAL transport (Drosophila melanogaster)
ABCA4 mediates atRAL transport (Gallus gallus)
ABCA4 mediates atRAL transport (Sus scrofa)
ABCA4 mediates atRAL transport (Bos taurus)
ABCA4 mediates atRAL transport (Canis familiaris)
ABCA4 mediates atRAL transport (Mus musculus)
NRPE is a substrate for Abca4 (Bos taurus)
ABCA4 transports NRPE from photoreceptor outer segment membrane to cytosol (Homo sapiens)
GRK1,4,7 phosphorylate MII to p-MII (Homo sapiens)
ABCA4 mediates atRAL transport (Homo sapiens)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Plasmodium falciparum)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Schizosaccharomyces pombe)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Caenorhabditis elegans)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Drosophila melanogaster)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Gallus gallus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Xenopus tropicalis)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Sus scrofa)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Bos taurus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Canis familiaris)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Rattus norvegicus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Mus musculus)
ABCB6 transports porphyrin from cytosol to mitchondrial matrix (Homo sapiens)
ABCB9 transports peptides from cytosol to lysosomal lumen (Schizosaccharomyces pombe)
ABCB9 transports peptides from cytosol to lysosomal lumen (Caenorhabditis elegans)
ABCB9 transports peptides from cytosol to lysosomal lumen (Gallus gallus)
ABCB9 transports peptides from cytosol to lysosomal lumen (Danio rerio)
ABCB9 transports peptides from cytosol to lysosomal lumen (Sus scrofa)
ABCB9 transports peptides from cytosol to lysosomal lumen (Bos taurus)
ABCB9 transports peptides from cytosol to lysosomal lumen (Canis familiaris)
ABCB9 transports peptides from cytosol to lysosomal lumen (Rattus norvegicus)
ABCB9 transports peptides from cytosol to lysosomal lumen (Mus musculus)
ABCB9 transports peptides from cytosol to lysosomal lumen (Homo sapiens)
CFTR transports Cl- from cytosol to extracellular region (Plasmodium falciparum)
CFTR transports Cl- from cytosol to extracellular region (Dictyostelium discoideum)
CFTR transports Cl- from cytosol to extracellular region (Caenorhabditis elegans)
CFTR transports Cl- from cytosol to extracellular region (Drosophila melanogaster)
CFTR transports Cl- from cytosol to extracellular region (Gallus gallus)
CFTR transports Cl- from cytosol to extracellular region (Xenopus tropicalis)
CFTR transports Cl- from cytosol to extracellular region (Danio rerio)
CFTR transports Cl- from cytosol to extracellular region (Sus scrofa)
CFTR transports Cl- from cytosol to extracellular region (Bos taurus)
CFTR transports Cl- from cytosol to extracellular region (Canis familiaris)
CFTR transports Cl- from cytosol to extracellular region (Rattus norvegicus)
CFTR transports Cl- from cytosol to extracellular region (Mus musculus)
CFTR transports Cl- from cytosol to extracellular region (Homo sapiens)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Plasmodium falciparum)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Schizosaccharomyces pombe)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Dictyostelium discoideum)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Gallus gallus)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Sus scrofa)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Bos taurus)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Canis familiaris)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Rattus norvegicus)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Mus musculus)
ABCA8,B1,B5 transport xenobiotics from cytosol to extracellular region (Homo sapiens)
HCO3- transport through ion channel (Plasmodium falciparum)
HCO3- transport through ion channel (Dictyostelium discoideum)
HCO3- transport through ion channel (Caenorhabditis elegans)
HCO3- transport through ion channel (Drosophila melanogaster)
HCO3- transport through ion channel (Gallus gallus)
HCO3- transport through ion channel (Xenopus tropicalis)
HCO3- transport through ion channel (Danio rerio)
HCO3- transport through ion channel (Sus scrofa)
HCO3- transport through ion channel (Bos taurus)
HCO3- transport through ion channel (Canis familiaris)
HCO3- transport through ion channel (Rattus norvegicus)
HCO3- transport through ion channel (Mus musculus)
HCO3- transport through ion channel (Homo sapiens)
The ABCC family mediates organic anion transport (Plasmodium falciparum)
The ABCC family mediates organic anion transport (Saccharomyces cerevisiae)
The ABCC family mediates organic anion transport (Schizosaccharomyces pombe)
The ABCC family mediates organic anion transport (Dictyostelium discoideum)
The ABCC family mediates organic anion transport (Caenorhabditis elegans)
The ABCC family mediates organic anion transport (Drosophila melanogaster)
The ABCC family mediates organic anion transport (Gallus gallus)
The ABCC family mediates organic anion transport (Xenopus tropicalis)
The ABCC family mediates organic anion transport (Danio rerio)
The ABCC family mediates organic anion transport (Sus scrofa)
The ABCC family mediates organic anion transport (Bos taurus)
The ABCC family mediates organic anion transport (Canis familiaris)
The ABCC family mediates organic anion transport (Rattus norvegicus)
The ABCC family mediates organic anion transport (Mus musculus)
The ABCC family mediates organic anion transport (Homo sapiens)
ABCA7:Apo1A-mediated phospholipid efflux (Sus scrofa)
ABCA7:Apo1A-mediated phospholipid efflux (Canis familiaris)
ABCA7:Apo1A-mediated phospholipid efflux (Rattus norvegicus)
ABCA7:Apo1A-mediated phospholipid efflux (Mus musculus)
ABCA7:Apo1A-mediated phospholipid efflux (Homo sapiens)
ABCA12 transports lipids from cytosol to extracellular region (Plasmodium falciparum)
ABCA12 transports lipids from cytosol to extracellular region (Dictyostelium discoideum)
ABCA12 transports lipids from cytosol to extracellular region (Caenorhabditis elegans)
ABCA12 transports lipids from cytosol to extracellular region (Drosophila melanogaster)
ABCA12 transports lipids from cytosol to extracellular region (Gallus gallus)
ABCA12 transports lipids from cytosol to extracellular region (Sus scrofa)
ABCA12 transports lipids from cytosol to extracellular region (Bos taurus)
ABCA12 transports lipids from cytosol to extracellular region (Canis familiaris)
ABCA12 transports lipids from cytosol to extracellular region (Rattus norvegicus)
ABCA12 transports lipids from cytosol to extracellular region (Mus musculus)
ABCA12 transports lipids from cytosol to extracellular region (Homo sapiens)
ABCG4 may mediate cholesterol efflux (Saccharomyces cerevisiae)
ABCG4 may mediate cholesterol efflux (Dictyostelium discoideum)
ABCG4 may mediate cholesterol efflux (Drosophila melanogaster)
ABCG4 may mediate cholesterol efflux (Gallus gallus)
ABCG4 may mediate cholesterol efflux (Xenopus tropicalis)
ABCG4 may mediate cholesterol efflux (Danio rerio)
ABCG4 may mediate cholesterol efflux (Bos taurus)
ABCG4 may mediate cholesterol efflux (Canis familiaris)
ABCG4 may mediate cholesterol efflux (Rattus norvegicus)
ABCG4 may mediate cholesterol efflux (Mus musculus)
ABCG4 may mediate cholesterol efflux (Homo sapiens)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Saccharomyces cerevisiae)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Dictyostelium discoideum)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Drosophila melanogaster)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Gallus gallus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Xenopus tropicalis)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Danio rerio)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Sus scrofa)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Bos taurus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Canis familiaris)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Rattus norvegicus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Mus musculus)
ABCG1-mediated transport of intracellular cholesterol to the cell surface (Homo sapiens)
ABCA3 transports PC, PG from ER membrane to lamellar body (Plasmodium falciparum)
ABCA3 transports PC, PG from ER membrane to lamellar body (Dictyostelium discoideum)
ABCA3 transports PC, PG from ER membrane to lamellar body (Caenorhabditis elegans)
ABCA3 transports PC, PG from ER membrane to lamellar body (Drosophila melanogaster)
ABCA3 transports PC, PG from ER membrane to lamellar body (Gallus gallus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Xenopus tropicalis)
ABCA3 transports PC, PG from ER membrane to lamellar body (Sus scrofa)
ABCA3 transports PC, PG from ER membrane to lamellar body (Bos taurus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Canis familiaris)
ABCA3 transports PC, PG from ER membrane to lamellar body (Rattus norvegicus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Mus musculus)
ABCA3 transports PC, PG from ER membrane to lamellar body (Homo sapiens)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Plasmodium falciparum)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Dictyostelium discoideum)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Caenorhabditis elegans)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Drosophila melanogaster)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Gallus gallus)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Sus scrofa)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Bos taurus)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Canis familiaris)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Rattus norvegicus)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Mus musculus)
ABCG5:ABCG8 transports sterols from cytosol to extracellular region (Homo sapiens)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Plasmodium falciparum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Dictyostelium discoideum)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Gallus gallus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Xenopus tropicalis)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Sus scrofa)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Bos taurus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Canis familiaris)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Rattus norvegicus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Mus musculus)
ABCA5 transports CHOL from lysosomal lumen to cytosol (Homo sapiens)
ABCAs mediate lipid efflux (Plasmodium falciparum)
ABCAs mediate lipid efflux (Dictyostelium discoideum)
ABCAs mediate lipid efflux (Gallus gallus)
ABCAs mediate lipid efflux (Sus scrofa)
ABCAs mediate lipid efflux (Rattus norvegicus)
ABCAs mediate lipid efflux (Mus musculus)
ABCAs mediate lipid efflux (Homo sapiens)
ABCAs mediate lipid influx (Plasmodium falciparum)
ABCAs mediate lipid influx (Dictyostelium discoideum)
ABCAs mediate lipid influx (Gallus gallus)
ABCAs mediate lipid influx (Sus scrofa)
ABCAs mediate lipid influx (Rattus norvegicus)
ABCAs mediate lipid influx (Mus musculus)
ABCAs mediate lipid influx (Homo sapiens)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Caenorhabditis elegans)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Gallus gallus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Xenopus tropicalis)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Sus scrofa)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Bos taurus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Canis familiaris)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Rattus norvegicus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Mus musculus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Homo sapiens)
ABCB4 transports PC from plasma membrane to extracellular region (Plasmodium falciparum)
ABCB4 transports PC from plasma membrane to extracellular region (Schizosaccharomyces pombe)
ABCB4 transports PC from plasma membrane to extracellular region (Dictyostelium discoideum)
ABCB4 transports PC from plasma membrane to extracellular region (Gallus gallus)
ABCB4 transports PC from plasma membrane to extracellular region (Sus scrofa)
ABCB4 transports PC from plasma membrane to extracellular region (Bos taurus)
ABCB4 transports PC from plasma membrane to extracellular region (Canis familiaris)
ABCB4 transports PC from plasma membrane to extracellular region (Rattus norvegicus)
ABCB4 transports PC from plasma membrane to extracellular region (Mus musculus)
ABCB4 transports PC from plasma membrane to extracellular region (Homo sapiens)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Drosophila melanogaster)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Gallus gallus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Xenopus tropicalis)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Danio rerio)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Sus scrofa)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Bos taurus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Canis familiaris)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Rattus norvegicus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Mus musculus)
Phosphorylation of Aquaporin-2 by Protein Kinase A (PKA) (Homo sapiens)
Eif2ak4 dimer autophosphorylates (Mus musculus)
GCN2 dimer autophosphorylates (Saccharomyces cerevisiae)
EIF2AK4 (GCN2) dimer autophosphorylates (Homo sapiens)
p-T-Eif2ak1 phosphorylates Eif2s1 (eIF2-alpha) (Mus musculus)
p-T-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Oryctolagus cuniculus)
p-T-Eif2ak1:ferriheme dimer autophosphorylates (Mus musculus)
p-T-EIF2AK1:ferriheme dimer autophosphorylates (Homo sapiens)
p-T,T486,T488-EIF2AK1 phosphorylates EIF2S1 (eIF2-alpha) (Homo sapiens)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Caenorhabditis elegans)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Drosophila melanogaster)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Gallus gallus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Xenopus tropicalis)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Sus scrofa)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Bos taurus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Canis familiaris)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Rattus norvegicus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Mus musculus)
EIF2AK3 (PERK) phosphorylates EIF2S1 (eIF2-alpha)Phosphorylation of eIF2-alpha by PERK (Homo sapiens)
GCN2 phosphorylates SUI2 (Saccharomyces cerevisiae)
Eif2ak4 phosphorylates Eif2s1 (Mus musculus)
p-T899-EIF2AK4 (GCN2) phosphorylates EIF2AS1 (Homo sapiens)
SQSTM1 oligomer is phosphorylated (Homo sapiens)
PRKCI phosphorylates NFE2L2 (Caenorhabditis elegans)
PRKCI phosphorylates NFE2L2 (Drosophila melanogaster)
PRKCI phosphorylates NFE2L2 (Gallus gallus)
PRKCI phosphorylates NFE2L2 (Danio rerio)
PRKCI phosphorylates NFE2L2 (Sus scrofa)
PRKCI phosphorylates NFE2L2 (Bos taurus)
PRKCI phosphorylates NFE2L2 (Canis familiaris)
PRKCI phosphorylates NFE2L2 (Rattus norvegicus)
PRKCI phosphorylates NFE2L2 (Mus musculus)
PRKCI phosphorylates NFE2L2 (Homo sapiens)
MAPKAPK2 phosphorylates HSF1 (Caenorhabditis elegans)
MAPKAPK2 phosphorylates HSF1 (Drosophila melanogaster)
MAPKAPK2 phosphorylates HSF1 (Gallus gallus)
MAPKAPK2 phosphorylates HSF1 (Sus scrofa)
MAPKAPK2 phosphorylates HSF1 (Bos taurus)
MAPKAPK2 phosphorylates HSF1 (Rattus norvegicus)
MAPKAPK2 phosphorylates HSF1 (Mus musculus)
MAPKAPK2 phosphorylates HSF1 (Homo sapiens)
Constitutive phosphorylation by GSK3 (Saccharomyces cerevisiae)
Constitutive phosphorylation by GSK3 (Schizosaccharomyces pombe)
Constitutive phosphorylation by GSK3 (Dictyostelium discoideum)
Constitutive phosphorylation by GSK3 (Caenorhabditis elegans)
Constitutive phosphorylation by GSK3 (Drosophila melanogaster)
Constitutive phosphorylation by GSK3 (Gallus gallus)
Constitutive phosphorylation by GSK3 (Sus scrofa)
Constitutive phosphorylation by GSK3 (Bos taurus)
Constitutive phosphorylation by GSK3 (Canis familiaris)
Constitutive phosphorylation by GSK3 (Rattus norvegicus)
Constitutive phosphorylation by GSK3 (Mus musculus)
Constitutive phosphorylation by GSK3 (Homo sapiens)
Constitutive phosphorylation by pERK1/2 (Saccharomyces cerevisiae)
Constitutive phosphorylation by pERK1/2 (Schizosaccharomyces pombe)
Constitutive phosphorylation by pERK1/2 (Dictyostelium discoideum)
Constitutive phosphorylation by pERK1/2 (Caenorhabditis elegans)
Constitutive phosphorylation by pERK1/2 (Drosophila melanogaster)
Constitutive phosphorylation by pERK1/2 (Gallus gallus)
Constitutive phosphorylation by pERK1/2 (Sus scrofa)
Constitutive phosphorylation by pERK1/2 (Bos taurus)
Constitutive phosphorylation by pERK1/2 (Canis familiaris)
Constitutive phosphorylation by pERK1/2 (Rattus norvegicus)
Constitutive phosphorylation by pERK1/2 (Mus musculus)
Constitutive phosphorylation by pERK1/2 (Homo sapiens)
HSP110s exchange ATP for ADP on HSP70s:ADP (Plasmodium falciparum)
HSP110s exchange ATP for ADP on HSP70s:ADP (Saccharomyces cerevisiae)
HSP110s exchange ATP for ADP on HSP70s:ADP (Schizosaccharomyces pombe)
HSP110s exchange ATP for ADP on HSP70s:ADP (Dictyostelium discoideum)
HSP110s exchange ATP for ADP on HSP70s:ADP (Caenorhabditis elegans)
HSP110s exchange ATP for ADP on HSP70s:ADP (Xenopus tropicalis)
HSP110s exchange ATP for ADP on HSP70s:ADP (Danio rerio)
HSP110s exchange ATP for ADP on HSP70s:ADP (Sus scrofa)
HSP110s exchange ATP for ADP on HSP70s:ADP (Bos taurus)
HSP110s exchange ATP for ADP on HSP70s:ADP (Canis familiaris)
HSP110s exchange ATP for ADP on HSP70s:ADP (Rattus norvegicus)
HSP110s exchange ATP for ADP on HSP70s:ADP (Mus musculus)
HSP110s exchange ATP for ADP on HSP70s:ADP (Homo sapiens)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Plasmodium falciparum)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Sus scrofa)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Bos taurus)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Canis familiaris)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Rattus norvegicus)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Mus musculus)
ABCG2 tetramer transports BMG,BDG from cytosol to extracellular region (Homo sapiens)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Schizosaccharomyces pombe)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Dictyostelium discoideum)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Caenorhabditis elegans)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Drosophila melanogaster)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Gallus gallus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Xenopus tropicalis)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Danio rerio)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Sus scrofa)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Bos taurus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Canis familiaris)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Rattus norvegicus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Mus musculus)
ABCC2 transports BMG,BDG from cytosol to extracellular region (Homo sapiens)
Phosphorylation of ITIM in SIRP alpha (Mus musculus)
Phosphorylation of ITIM in SIRP alpha (Rattus norvegicus)
Phosphorylation of ITIM motif in SIRP alpha (Homo sapiens)
Phosphorylation of nephrin by FYN (Caenorhabditis elegans)
Phosphorylation of nephrin by FYN (Drosophila melanogaster)
Phosphorylation of nephrin by FYN (Danio rerio)
Phosphorylation of nephrin by FYN (Sus scrofa)
Phosphorylation of nephrin by FYN (Bos taurus)
Phosphorylation of nephrin by FYN (Canis familiaris)
Phosphorylation of nephrin by FYN (Rattus norvegicus)
Phosphorylation of nephrin by FYN (Mus musculus)
Phosphorylation of nephrin by FYN (Homo sapiens)
Unknown kinase phosphorylates 9b (Homo sapiens)
STAT3 activation (Rattus norvegicus)
STAT3 activation (Homo sapiens)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR4- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR4-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Xenopus tropicalis)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Sus scrofa)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR4-associated FRS2. (Caenorhabditis elegans)
CBL is tyrosine phosphorylated (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR2-associated FRS2 (Homo sapiens)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR2- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR2-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Activated FGFR2 phosphorylates PPTN11 (Drosophila melanogaster)
Activated FGFR2 phosphorylates PPTN11 (Gallus gallus)
Activated FGFR2 phosphorylates PPTN11 (Xenopus tropicalis)
Activated FGFR2 phosphorylates PPTN11 (Danio rerio)
Activated FGFR2 phosphorylates PPTN11 (Sus scrofa)
Activated FGFR2 phosphorylates PPTN11 (Bos taurus)
Activated FGFR2 phosphorylates PPTN11 (Canis familiaris)
Activated FGFR2 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR2 phosphorylates PPTN11 (Mus musculus)
Activated FGFR2 phosphorylates PPTN11 (Homo sapiens)
PRLR is phosphorylated at Ser-349 (Gallus gallus)
PRLR is phosphorylated at Ser-349 (Xenopus tropicalis)
PRLR is phosphorylated at Ser-349 (Sus scrofa)
PRLR is phosphorylated at Ser-349 (Canis familiaris)
PRLR is phosphorylated at Ser-349 (Rattus norvegicus)
PRLR is phosphorylated at Ser-349 (Mus musculus)
PRLR is phosphorylated at Ser-349 (Homo sapiens)
Shp2 is phosphorylated (Rattus norvegicus)
SHP2 is phosphorylated (Homo sapiens)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Drosophila melanogaster)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Gallus gallus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Xenopus tropicalis)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Danio rerio)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Sus scrofa)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Bos taurus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Canis familiaris)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Rattus norvegicus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Mus musculus)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Homo sapiens)
Conversion of PIP2 into PIP3 by PI3K bound to p-ERBB4cyt1 homodimers (Caenorhabditis elegans)
Prlr-bound Stat5 is phosphorylated (Rattus norvegicus)
Tyrosine phosphorylation of Prlr (Rattus norvegicus)
JAK2 phosphorylation (Gallus gallus)
JAK2 phosphorylation (Xenopus tropicalis)
JAK2 phosphorylation (Danio rerio)
JAK2 phosphorylation (Sus scrofa)
JAK2 phosphorylation (Canis familiaris)
JAK2 phosphorylation (Rattus norvegicus)
JAK2 phosphorylation (Mus musculus)
JAK2 phosphorylation (Homo sapiens)
Tyrosine phosphorylation of PRLR (Homo sapiens)
PRLR-bound STAT5 is phosphorylated (Homo sapiens)
IL21 receptor STAT phosphorylation (Gallus gallus)
IL21 receptor STAT phosphorylation (Danio rerio)
IL21 receptor STAT phosphorylation (Sus scrofa)
IL21 receptor STAT phosphorylation (Bos taurus)
IL21 receptor STAT phosphorylation (Canis familiaris)
IL21 receptor STAT phosphorylation (Rattus norvegicus)
IL21 receptor STAT phosphorylation (Mus musculus)
IL21 receptor STAT phosphorylation (Homo sapiens)
IL21 receptor JAK phosphorylation (Gallus gallus)
IL21 receptor JAK phosphorylation (Danio rerio)
IL21 receptor JAK phosphorylation (Sus scrofa)
IL21 receptor JAK phosphorylation (Bos taurus)
IL21 receptor JAK phosphorylation (Canis familiaris)
IL21 receptor JAK phosphorylation (Rattus norvegicus)
IL21 receptor JAK phosphorylation (Mus musculus)
IL21 receptor JAK phosphorylation (Homo sapiens)
SYK is a substrate for JAK1 (Sus scrofa)
SYK is a substrate for JAK1 (Bos taurus)
SYK is a substrate for JAK1 (Canis familiaris)
SYK is a substrate for JAK1 (Rattus norvegicus)
SYK is a substrate for JAK1 (Mus musculus)
SYK is a substrate for JAK1 (Homo sapiens)
Jak2 Phosphorylates Stat5 in Response to Leptin (Mus musculus)
Activation of STAT5a/b by JAK2 (Gallus gallus)
Activation of STAT5a/b by JAK2 (Sus scrofa)
Activation of STAT5a/b by JAK2 (Bos taurus)
Activation of STAT5a/b by JAK2 (Canis familiaris)
Activation of STAT5a/b by JAK2 (Rattus norvegicus)
Activation of STAT5a/b by JAK2 (Mus musculus)
JAK2 is phosphorylated, activated (Gallus gallus)
JAK2 is phosphorylated, activated (Sus scrofa)
JAK2 is phosphorylated, activated (Bos taurus)
JAK2 is phosphorylated, activated (Canis familiaris)
JAK2 is phosphorylated, activated (Rattus norvegicus)
JAK2 is phosphorylated, activated (Mus musculus)
JAK2 is phosphorylated, activated (Homo sapiens)
Activation of STAT5a/b by JAK2 (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Gallus gallus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Sus scrofa)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Bos taurus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Canis familiaris)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Rattus norvegicus)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Mus musculus)
IL7r is phosphorylated on Y449 (Mus musculus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Gallus gallus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Sus scrofa)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Bos taurus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Canis familiaris)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Rattus norvegicus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Mus musculus)
JAK3 in IL7:p-Y449-IL7R:JAK1:IL2RG:JAK3 is phosphorylated (Homo sapiens)
IL7R is phosphorylated on Y499 (Homo sapiens)
IL7:p-Y449-IL7R:JAK1:IL2RG:p-JAK3:STAT5A,STAT5B phosphorylates STAT5 (Homo sapiens)
Epo:p-8Y-Epor:p-12Y-Jak2:Lyn:Irs2 phosphorylates Stat5 (Mus musculus)
Phospho-Jak2 phosphorylates Epor (Mus musculus)
Jak2 transphosphorylates and is activated in response to Erythropoietin (Mus musculus)
JAK2 transphosphorylates and is activated in response to Erythropoietin (Homo sapiens)
Phospho-JAK2 phosphorylates EPOR (Homo sapiens)
JAK2 and LYN phosphorylate STAT5 in EPO:phospho-EPOR:phospho-JAK2:LYN:IRS2 (Homo sapiens)
Recruited STAT5 is phosphorylated (Sus scrofa)
Recruited STAT5 is phosphorylated (Bos taurus)
Recruited STAT5 is phosphorylated (Canis familiaris)
Recruited STAT5 is phosphorylated (Rattus norvegicus)
Recruited STAT5 is phosphorylated (Mus musculus)
Recruited STAT5 is phosphorylated (Homo sapiens)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Gallus gallus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Sus scrofa)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Bos taurus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Canis familiaris)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Rattus norvegicus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Mus musculus)
SHC1 mediates cytokine-induced phosphorylation of GAB2 (Homo sapiens)
Il15:Il15ra:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3:p-Y-Shc1:Grb2:Gab2 phosphorylates Gab2 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3:p-Y-SHC1:GRB2:GAB2 phosphorylates GAB2 (Homo sapiens)
Il15ra:Il15:p-Y-Il2rb:p-Y-Jak1:p-Y-Il2rg:p-Y-Jak3 phosphorylates Shc1 (Mus musculus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates SHC1 (Homo sapiens)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Sus scrofa)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Bos taurus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Canis familiaris)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Rattus norvegicus)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Mus musculus)
Il2rb and Il2rg are phosphorylated (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Sus scrofa)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Bos taurus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Canis familiaris)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Rattus norvegicus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Mus musculus)
IL15RA:IL15:IL2RB:JAK1:IL2RG:JAK3 phosphorylates JAK3 and JAK1 (Homo sapiens)
IL2RB and IL2RG are phosphorylated (Homo sapiens)
IL15:IL15RA:p-Y-IL2RB:p-Y-JAK1:p-Y-IL2RG:p-Y-JAK3 phosphorylates STAT3 and STAT5 (Homo sapiens)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Gallus gallus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Sus scrofa)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Bos taurus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Canis familiaris)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Rattus norvegicus)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Mus musculus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Gallus gallus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Sus scrofa)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Bos taurus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Canis familiaris)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Rattus norvegicus)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Mus musculus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Gallus gallus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Sus scrofa)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Bos taurus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Canis familiaris)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Rattus norvegicus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Mus musculus)
IL9:IL9R:JAK1:IL2RG:JAK3 phosphorylates JAK3 (Homo sapiens)
IL9R is phosphorylated by IL9:IL9R:JAK1:IL2RG:p-Y904,939-JAK3 (Homo sapiens)
IL9:p-Y116-IL9R:JAK1:IL2RG:p-904,939-JAK3:STAT3 phosphorylates STAT1, STAT3 or STAT5 (Homo sapiens)
PTK2 autophosphorylates downstream of EGFR (Caenorhabditis elegans)
PTK2 autophosphorylates downstream of EGFR (Gallus gallus)
PTK2 autophosphorylates downstream of EGFR (Bos taurus)
PTK2 autophosphorylates downstream of EGFR (Canis familiaris)
PTK2 autophosphorylates downstream of EGFR (Rattus norvegicus)
PTK2 autophosphorylates downstream of EGFR (Mus musculus)
PTK2 autophosphorylates downstream of EGFR (Homo sapiens)
Phosphorylation of CTLA-4 (Sus scrofa)
Phosphorylation of CTLA-4 (Bos taurus)
Phosphorylation of CTLA-4 (Canis familiaris)
Phosphorylation of CTLA-4 (Rattus norvegicus)
Phosphorylation of CTLA-4 (Mus musculus)
Phosphorylation of CTLA-4 (Homo sapiens)
Phosphorylation of PD-1 (Gallus gallus)
Phosphorylation of PD-1 (Sus scrofa)
Phosphorylation of PD-1 (Bos taurus)
Phosphorylation of PD-1 (Canis familiaris)
Phosphorylation of PD-1 (Rattus norvegicus)
Phosphorylation of PD-1 (Mus musculus)
Phosphorylation of PD-1 (Homo sapiens)
Hvem induses Btla phosphorylation (Mus musculus)
HVEM induses BTLA phosphorylation (Homo sapiens)
p-S400-Cot phosphorylates NIK (Saccharomyces cerevisiae)
p-S400-Cot phosphorylates NIK (Gallus gallus)
p-S400-Cot phosphorylates NIK (Xenopus tropicalis)
p-S400-Cot phosphorylates NIK (Sus scrofa)
p-S400-Cot phosphorylates NIK (Bos taurus)
p-S400-Cot phosphorylates NIK (Canis familiaris)
p-S400-Cot phosphorylates NIK (Rattus norvegicus)
p-S400-Cot phosphorylates NIK (Mus musculus)
AKT interacts and phosphorylates Cot (Saccharomyces cerevisiae)
AKT interacts and phosphorylates Cot (Gallus gallus)
AKT interacts and phosphorylates Cot (Rattus norvegicus)
AKT interacts and phosphorylates Cot (Mus musculus)
AKT interacts and phosphorylates Cot (Homo sapiens)
p-S400-Cot phosphorylates NIK (Homo sapiens)
Activated Ntrk2 phosphorylates Shc1 (Rattus norvegicus)
NTRK2 phosphorylates SHC1 (Homo sapiens)
Src phosphorylates Ntrk2 (Rattus norvegicus)
SRC,FYN phosphorylate NTRK2 (Homo sapiens)
Fyn-mediated phosphorylation of Grin2b (Rattus norvegicus)
Ntrk2-bound Fyn autophosphorylates (Rattus norvegicus)
NTRK2-bound FYN autophosphorylates (Homo sapiens)
FYN-mediated phosphorylation of GRIN2B (Homo sapiens)
Activated Ntrk2 activates PI3K signaling (Mus musculus)
NTRK2-activated PI3K generates PIP3 (Homo sapiens)
BDNF- or NTF4-activated Ntrk2 phosphorylates Plcg1 (Homo sapiens)
NTF3-bound Ntrk2 dimers trans-autophosphorylate (Homo sapiens)
NTF3-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
NTRK2 phosphorylates PLCG1 (Homo sapiens)
Ntrk2 promotes Tiam1 phosphorylation (Homo sapiens)
NTRK2 promotes TIAM1 phosphorylation (Homo sapiens)
Cdk5 phosphorylates Ntrk2 (Homo sapiens)
Ntrk2 phosohorylates CDK5 (Homo sapiens)
NTRK2 phosphorylates CDK5 (Homo sapiens)
CDK5 phosphorylates NTRK2 (Homo sapiens)
Ntrk2 phosphorylates FRS3 (Homo sapiens)
BDNF-bound Ntrk2 dimers trans-autophosphorylate (Homo sapiens)
BDNF-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
NTF4-bound Ntrk2 dimers trans-autophosphorylate (Homo sapiens)
NTF4-bound NTRK2 dimers trans-autophosphorylate (Homo sapiens)
NTRK2 phosphorylates FRS3 (Homo sapiens)
Ntrk2 phosphorylates Frs2 (Homo sapiens)
NTRK2 phosphorylates FRS2 (Homo sapiens)
Ntrk3 phosphorylates Shc1 (Homo sapiens)
NTRK3 phosphorylates SHC1 (Homo sapiens)
Activated Ntrk3 stimulates PI3K activity (Mus musculus)
Activated NTRK3 promotes SRC autophosphorylation (Gallus gallus)
Activated NTRK3 promotes SRC autophosphorylation (Sus scrofa)
Activated NTRK3 promotes SRC autophosphorylation (Bos taurus)
Activated NTRK3 promotes SRC autophosphorylation (Canis familiaris)
Activated NTRK3 promotes SRC autophosphorylation (Rattus norvegicus)
Activated NTRK3 promotes SRC autophosphorylation (Mus musculus)
Activated NTRK3 promotes SRC autophosphorylation (Homo sapiens)
Activated NTRK3 stimulates PI3K activity (Homo sapiens)
NTRK3 dimers trans-autophosphorylate (Gallus gallus)
NTRK3 dimers trans-autophosphorylate (Sus scrofa)
NTRK3 dimers trans-autophosphorylate (Bos taurus)
NTRK3 dimers trans-autophosphorylate (Canis familiaris)
NTRK3 dimers trans-autophosphorylate (Rattus norvegicus)
NTRK3 dimers trans-autophosphorylate (Mus musculus)
NTRK3 dimers trans-autophosphorylate (Homo sapiens)
Ntrk3 phosphorylates Plcg1 (Homo sapiens)
NTRK3 phosphorylates PLCG1 (Homo sapiens)
Phosphorylation of YAP by LATS2 (Caenorhabditis elegans)
Phosphorylation of YAP by LATS2 (Gallus gallus)
Phosphorylation of YAP by LATS2 (Danio rerio)
Phosphorylation of YAP by LATS2 (Sus scrofa)
Phosphorylation of YAP by LATS2 (Bos taurus)
Phosphorylation of YAP by LATS2 (Canis familiaris)
Phosphorylation of YAP by LATS2 (Rattus norvegicus)
Phosphorylation of YAP by LATS2 (Mus musculus)
Phosphorylation of YAP by LATS2 (Homo sapiens)
Phosphorylation of YAP by LATS1 (Caenorhabditis elegans)
Phosphorylation of YAP by LATS1 (Gallus gallus)
Phosphorylation of YAP by LATS1 (Xenopus tropicalis)
Phosphorylation of YAP by LATS1 (Danio rerio)
Phosphorylation of YAP by LATS1 (Sus scrofa)
Phosphorylation of YAP by LATS1 (Bos taurus)
Phosphorylation of YAP by LATS1 (Canis familiaris)
Phosphorylation of YAP by LATS1 (Rattus norvegicus)
Phosphorylation of YAP by LATS1 (Mus musculus)
Phosphorylation of YAP by LATS1 (Homo sapiens)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Caenorhabditis elegans)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Gallus gallus)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Danio rerio)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Sus scrofa)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Bos taurus)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Canis familiaris)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Rattus norvegicus)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Mus musculus)
Phosphorylation of WWTR1 (TAZ) by LATS2 (Homo sapiens)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Caenorhabditis elegans)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Gallus gallus)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Xenopus tropicalis)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Danio rerio)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Sus scrofa)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Bos taurus)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Canis familiaris)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Rattus norvegicus)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Caenorhabditis elegans)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Drosophila melanogaster)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Gallus gallus)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Xenopus tropicalis)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Danio rerio)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Sus scrofa)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Bos taurus)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Canis familiaris)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Rattus norvegicus)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK3 (p-MST2) (Homo sapiens)
Phosphorylation of WWTR1 (TAZ) by LATS1 (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Caenorhabditis elegans)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Drosophila melanogaster)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Gallus gallus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Xenopus tropicalis)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Danio rerio)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Sus scrofa)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Bos taurus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Canis familiaris)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Rattus norvegicus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK3 (MST2)/N (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Caenorhabditis elegans)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Drosophila melanogaster)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Gallus gallus)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Xenopus tropicalis)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Sus scrofa)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Bos taurus)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Canis familiaris)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Rattus norvegicus)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK4(MST1)/N (Homo sapiens)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Caenorhabditis elegans)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Drosophila melanogaster)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Gallus gallus)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Xenopus tropicalis)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Sus scrofa)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Bos taurus)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Canis familiaris)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Rattus norvegicus)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Mus musculus)
Phosphorylation of LATS1 and 2 by p-STK4 (p-MST1) (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Caenorhabditis elegans)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Drosophila melanogaster)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Gallus gallus)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Xenopus tropicalis)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Danio rerio)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Sus scrofa)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Bos taurus)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Canis familiaris)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Rattus norvegicus)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Mus musculus)
Phosphorylation of MOB1A and B by p-STK3(MST2)/N (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Caenorhabditis elegans)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Drosophila melanogaster)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Gallus gallus)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Xenopus tropicalis)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Sus scrofa)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Bos taurus)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Canis familiaris)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Rattus norvegicus)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Mus musculus)
Phosphorylation of MOB1A and B by p-STK4(MST1)/N (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Caenorhabditis elegans)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Drosophila melanogaster)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Gallus gallus)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Xenopus tropicalis)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Sus scrofa)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Bos taurus)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Canis familiaris)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Rattus norvegicus)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Mus musculus)
Phosphorylation of MOB1A and B by p-STK4 (p-MST1) (Homo sapiens)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Caenorhabditis elegans)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Drosophila melanogaster)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Gallus gallus)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Xenopus tropicalis)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Sus scrofa)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Bos taurus)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Canis familiaris)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Rattus norvegicus)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Mus musculus)
Phosphorylation of STK4 (MST1) and SAV1 by STK4 (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Caenorhabditis elegans)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Drosophila melanogaster)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Gallus gallus)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Xenopus tropicalis)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Danio rerio)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Sus scrofa)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Bos taurus)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Canis familiaris)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Rattus norvegicus)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Mus musculus)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Caenorhabditis elegans)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Drosophila melanogaster)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Gallus gallus)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Xenopus tropicalis)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Danio rerio)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Sus scrofa)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Bos taurus)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Canis familiaris)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Rattus norvegicus)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Mus musculus)
Phosphorylation of STK3 (MST2) and SAV1 by STK3 (Homo sapiens)
Phosphorylation of MOB1A and B by p-STK3 (p-MST2) (Homo sapiens)
GSK3 phosphorylates p-Gli2 (Mus musculus)
CK1 phosphorylates p-Gli2 (Mus musculus)
Pka phosphorylates Gli2 (Mus musculus)
PKA phosphorylates GLI2 (Homo sapiens)
CK1 phosphorylates p-GLI2 (Homo sapiens)
GSK3 phosphorylates p-GLI2 (Homo sapiens)
Pka phosphorylates GLI1 (Mus musculus)
PKA phosphorylates GLI1 (Homo sapiens)
GSK3 phosphorylates p-GLI3 (Drosophila melanogaster)
GSK3 phosphorylates p-GLI3 (Gallus gallus)
GSK3 phosphorylates p-GLI3 (Sus scrofa)
GSK3 phosphorylates p-GLI3 (Bos taurus)
GSK3 phosphorylates p-GLI3 (Canis familiaris)
GSK3 phosphorylates p-GLI3 (Rattus norvegicus)
GSK3 phosphorylates p-GLI3 (Mus musculus)
CK1 phosphorylates p-GLI3 (Drosophila melanogaster)
CK1 phosphorylates p-GLI3 (Gallus gallus)
CK1 phosphorylates p-GLI3 (Danio rerio)
CK1 phosphorylates p-GLI3 (Sus scrofa)
CK1 phosphorylates p-GLI3 (Bos taurus)
CK1 phosphorylates p-GLI3 (Canis familiaris)
CK1 phosphorylates p-GLI3 (Rattus norvegicus)
CK1 phosphorylates p-GLI3 (Mus musculus)
PKA phosphorylates GLI3 (Drosophila melanogaster)
PKA phosphorylates GLI3 (Gallus gallus)
PKA phosphorylates GLI3 (Xenopus tropicalis)
PKA phosphorylates GLI3 (Danio rerio)
PKA phosphorylates GLI3 (Sus scrofa)
PKA phosphorylates GLI3 (Bos taurus)
PKA phosphorylates GLI3 (Canis familiaris)
PKA phosphorylates GLI3 (Rattus norvegicus)
PKA phosphorylates GLI3 (Mus musculus)
PKA phosphorylates GLI3 (Homo sapiens)
CK1 phosphorylates p-GLI3 (Homo sapiens)
GSK3 phosphorylates p-GLI3 (Homo sapiens)
Src,Yes1 phosphorylate Yap1 (Rattus norvegicus)
SRC,YES1 phosphorylate YAP1 (Homo sapiens)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Caenorhabditis elegans)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Drosophila melanogaster)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Gallus gallus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Xenopus tropicalis)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Danio rerio)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Sus scrofa)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Bos taurus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Canis familiaris)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Rattus norvegicus)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Mus musculus)
Type II receptor phosphorylates type I receptor (Caenorhabditis elegans)
Type II receptor phosphorylates type I receptor (Drosophila melanogaster)
Type II receptor phosphorylates type I receptor (Gallus gallus)
Type II receptor phosphorylates type I receptor (Xenopus tropicalis)
Type II receptor phosphorylates type I receptor (Danio rerio)
Type II receptor phosphorylates type I receptor (Sus scrofa)
Type II receptor phosphorylates type I receptor (Bos taurus)
Type II receptor phosphorylates type I receptor (Canis familiaris)
Type II receptor phosphorylates type I receptor (Rattus norvegicus)
Type II receptor phosphorylates type I receptor (Mus musculus)
Type II receptor phosphorylates type I receptor (Homo sapiens)
Activated type I receptor phosphorylates R-Smad1/5/8 directly (Homo sapiens)
EGFR phosphorylates NOTCH3 (Gallus gallus)
EGFR phosphorylates NOTCH3 (Xenopus tropicalis)
EGFR phosphorylates NOTCH3 (Rattus norvegicus)
EGFR phosphorylates NOTCH3 (Mus musculus)
EGFR phosphorylates NOTCH3 (Homo sapiens)
AKT1 phosphorylates NOTCH4 (Caenorhabditis elegans)
AKT1 phosphorylates NOTCH4 (Drosophila melanogaster)
AKT1 phosphorylates NOTCH4 (Gallus gallus)
AKT1 phosphorylates NOTCH4 (Rattus norvegicus)
AKT1 phosphorylates NOTCH4 (Mus musculus)
AKT1 phosphorylates NOTCH4 (Homo sapiens)
SRC phosphorylates RUNX3 (Caenorhabditis elegans)
SRC phosphorylates RUNX3 (Drosophila melanogaster)
SRC phosphorylates RUNX3 (Gallus gallus)
SRC phosphorylates RUNX3 (Danio rerio)
SRC phosphorylates RUNX3 (Sus scrofa)
SRC phosphorylates RUNX3 (Bos taurus)
SRC phosphorylates RUNX3 (Canis familiaris)
SRC phosphorylates RUNX3 (Rattus norvegicus)
SRC phosphorylates RUNX3 (Mus musculus)
SRC phosphorylates RUNX3 (Homo sapiens)
p-T774-PKN1 phosphorylates PPP1R14A (Caenorhabditis elegans)
p-T774-PKN1 phosphorylates PPP1R14A (Drosophila melanogaster)
p-T774-PKN1 phosphorylates PPP1R14A (Danio rerio)
p-T774-PKN1 phosphorylates PPP1R14A (Sus scrofa)
p-T774-PKN1 phosphorylates PPP1R14A (Bos taurus)
p-T774-PKN1 phosphorylates PPP1R14A (Canis familiaris)
p-T774-PKN1 phosphorylates PPP1R14A (Rattus norvegicus)
p-T774-PKN1 phosphorylates PPP1R14A (Mus musculus)
p-T774-PKN1 phosphorylates PPP1R14A (Homo sapiens)
SFKs phosphorylates RAF1 on Y340,Y341 (Caenorhabditis elegans)
SFKs phosphorylates RAF1 on Y340,Y341 (Drosophila melanogaster)
SFKs phosphorylates RAF1 on Y340,Y341 (Xenopus tropicalis)
SFKs phosphorylates RAF1 on Y340,Y341 (Canis familiaris)
SFKs phosphorylates RAF1 on Y340,Y341 (Rattus norvegicus)
SFKs phosphorylates RAF1 on Y340,Y341 (Mus musculus)
SFKs phosphorylates RAF1 on Y340,Y341 (Homo sapiens)
PAK phosphorylates p21 RAF1 on S338 (Caenorhabditis elegans)
PAK phosphorylates p21 RAF1 on S338 (Drosophila melanogaster)
PAK phosphorylates p21 RAF1 on S338 (Xenopus tropicalis)
PAK phosphorylates p21 RAF1 on S338 (Canis familiaris)
PAK phosphorylates p21 RAF1 on S338 (Rattus norvegicus)
PAK phosphorylates p21 RAF1 on S338 (Mus musculus)
PAK phosphorylates p21 RAF1 on S338 (Homo sapiens)
PAK phosphorylates p21 RAF1 on S338 (Gallus gallus)
SFKs phosphorylates RAF1 on Y340,Y341 (Gallus gallus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Drosophila melanogaster)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Xenopus tropicalis)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Sus scrofa)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Bos taurus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Canis familiaris)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Rattus norvegicus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Mus musculus)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Homo sapiens)
Active NIK:p-S176,180-IKKA dimer phosphorylates p100:RELB (Gallus gallus)
Active NIK phosphorylates IKKA dimer (Xenopus tropicalis)
Active NIK phosphorylates IKKA dimer (Sus scrofa)
Active NIK phosphorylates IKKA dimer (Bos taurus)
Active NIK phosphorylates IKKA dimer (Canis familiaris)
Active NIK phosphorylates IKKA dimer (Rattus norvegicus)
Active NIK phosphorylates IKKA dimer (Mus musculus)
Active NIK phosphorylates IKKA dimer (Homo sapiens)
Active NIK phosphorylates IKKA dimer (Gallus gallus)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Drosophila melanogaster)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Xenopus tropicalis)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Sus scrofa)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Bos taurus)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Canis familiaris)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Rattus norvegicus)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Mus musculus)
SYK autophosphorylates (Sus scrofa)
SYK autophosphorylates (Bos taurus)
SYK autophosphorylates (Canis familiaris)
SYK autophosphorylates (Rattus norvegicus)
SYK autophosphorylates (Mus musculus)
SYK autophosphorylates (Homo sapiens)
SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Homo sapiens)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Danio rerio)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Sus scrofa)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Bos taurus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Canis familiaris)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Rattus norvegicus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Mus musculus)
LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Homo sapiens)
Translocation of antigenic peptides back to phagosomes via TAP (Gallus gallus)
Translocation of antigenic peptides back to phagosomes via TAP (Homo sapiens)
IKKB phosphorylates SNAP23 (Homo sapiens)
Ribosomal scanning (Plasmodium falciparum)
Ribosomal scanning (Saccharomyces cerevisiae)
Ribosomal scanning (Schizosaccharomyces pombe)
Ribosomal scanning (Dictyostelium discoideum)
Ribosomal scanning (Caenorhabditis elegans)
Ribosomal scanning (Drosophila melanogaster)
Ribosomal scanning (Gallus gallus)
Ribosomal scanning (Xenopus tropicalis)
Ribosomal scanning (Danio rerio)
Ribosomal scanning (Sus scrofa)
Ribosomal scanning (Bos taurus)
Ribosomal scanning (Canis familiaris)
Ribosomal scanning (Rattus norvegicus)
Ribosomal scanning (Homo sapiens)
Ribosomal scanning (Mus musculus)
INF-gamma induced phosphorylation of L13a (Homo sapiens)
Cap-bound mRNA is activated by helicases (Plasmodium falciparum)
Cap-bound mRNA is activated by helicases (Saccharomyces cerevisiae)
Cap-bound mRNA is activated by helicases (Schizosaccharomyces pombe)
Cap-bound mRNA is activated by helicases (Canis familiaris)
Cap-bound mRNA is activated by helicases (Homo sapiens)
Cap-bound mRNA is activated by helicases (Mus musculus)
p-PKR dimer phosphorylates eIF2-alpha (Homo sapiens)
p-PKR dimer phosphorylates HIV tat (Homo sapiens)
p-PKR dimer phosphorylates PTPN2 (Drosophila melanogaster)
p-PKR dimer phosphorylates PTPN2 (Gallus gallus)
p-PKR dimer phosphorylates PTPN2 (Danio rerio)
p-PKR dimer phosphorylates PTPN2 (Sus scrofa)
p-PKR dimer phosphorylates PTPN2 (Bos taurus)
p-PKR dimer phosphorylates PTPN2 (Canis familiaris)
p-PKR dimer phosphorylates PTPN2 (Rattus norvegicus)
p-PKR dimer phosphorylates PTPN2 (Mus musculus)
p-PKR dimer phosphorylates PTPN2 (Homo sapiens)
p-PKR dimer phosphorylates MKK6 (Caenorhabditis elegans)
p-PKR dimer phosphorylates MKK6 (Drosophila melanogaster)
p-PKR dimer phosphorylates MKK6 (Gallus gallus)
p-PKR dimer phosphorylates MKK6 (Xenopus tropicalis)
p-PKR dimer phosphorylates MKK6 (Danio rerio)
p-PKR dimer phosphorylates MKK6 (Sus scrofa)
p-PKR dimer phosphorylates MKK6 (Bos taurus)
p-PKR dimer phosphorylates MKK6 (Canis familiaris)
p-PKR dimer phosphorylates MKK6 (Rattus norvegicus)
p-PKR dimer phosphorylates MKK6 (Mus musculus)
p-PKR dimer phosphorylates MKK6 (Homo sapiens)
p-PKR dimer phosphorylates PPP2R5A (Caenorhabditis elegans)
p-PKR dimer phosphorylates PPP2R5A (Drosophila melanogaster)
p-PKR dimer phosphorylates PPP2R5A (Sus scrofa)
p-PKR dimer phosphorylates PPP2R5A (Bos taurus)
p-PKR dimer phosphorylates PPP2R5A (Canis familiaris)
p-PKR dimer phosphorylates PPP2R5A (Rattus norvegicus)
p-PKR dimer phosphorylates PPP2R5A (Mus musculus)
p-PKR dimer phosphorylates PPP2R5A (Homo sapiens)
p-PKR dimer phosphorylates DHX9 (Caenorhabditis elegans)
p-PKR dimer phosphorylates DHX9 (Drosophila melanogaster)
p-PKR dimer phosphorylates DHX9 (Xenopus tropicalis)
p-PKR dimer phosphorylates DHX9 (Sus scrofa)
p-PKR dimer phosphorylates DHX9 (Bos taurus)
p-PKR dimer phosphorylates DHX9 (Canis familiaris)
p-PKR dimer phosphorylates DHX9 (Rattus norvegicus)
p-PKR dimer phosphorylates DHX9 (Mus musculus)
p-PKR dimer phosphorylates DHX9 (Homo sapiens)
p-PKR dimer phosphorylates MAPT (Sus scrofa)
p-PKR dimer phosphorylates MAPT (Canis familiaris)
p-PKR dimer phosphorylates MAPT (Rattus norvegicus)
p-PKR dimer phosphorylates MAPT (Mus musculus)
p-PKR dimer phosphorylates MAPT (Homo sapiens)
p-PKR dimer phosphorylates CDK1 (Caenorhabditis elegans)
p-PKR dimer phosphorylates CDK1 (Drosophila melanogaster)
p-PKR dimer phosphorylates CDK1 (Gallus gallus)
p-PKR dimer phosphorylates CDK1 (Xenopus tropicalis)
p-PKR dimer phosphorylates CDK1 (Danio rerio)
p-PKR dimer phosphorylates CDK1 (Sus scrofa)
p-PKR dimer phosphorylates CDK1 (Bos taurus)
p-PKR dimer phosphorylates CDK1 (Canis familiaris)
p-PKR dimer phosphorylates CDK1 (Rattus norvegicus)
p-PKR dimer phosphorylates CDK1 (Mus musculus)
p-PKR dimer phosphorylates CDK1 (Homo sapiens)
p-PKR dimer phosphorylates ILF3:ILF2 (Caenorhabditis elegans)
p-PKR dimer phosphorylates ILF3:ILF2 (Drosophila melanogaster)
p-PKR dimer phosphorylates ILF3:ILF2 (Gallus gallus)
p-PKR dimer phosphorylates ILF3:ILF2 (Xenopus tropicalis)
p-PKR dimer phosphorylates ILF3:ILF2 (Danio rerio)
p-PKR dimer phosphorylates ILF3:ILF2 (Sus scrofa)
p-PKR dimer phosphorylates ILF3:ILF2 (Bos taurus)
p-PKR dimer phosphorylates ILF3:ILF2 (Canis familiaris)
p-PKR dimer phosphorylates ILF3:ILF2 (Rattus norvegicus)
p-PKR dimer phosphorylates ILF3:ILF2 (Mus musculus)
p-PKR dimer phosphorylates ILF3:ILF2 (Homo sapiens)
p-PKR dimer phosphorylates SNCA (Gallus gallus)
p-PKR dimer phosphorylates SNCA (Xenopus tropicalis)
p-PKR dimer phosphorylates SNCA (Sus scrofa)
p-PKR dimer phosphorylates SNCA (Bos taurus)
p-PKR dimer phosphorylates SNCA (Canis familiaris)
p-PKR dimer phosphorylates SNCA (Rattus norvegicus)
p-PKR dimer phosphorylates SNCA (Mus musculus)
PKR dimer autophosphorylates (Homo sapiens)
p-PKR dimer phosphorylates SNCA (Homo sapiens)
p-MAPK2/3 phosphorylates HSP27 (Caenorhabditis elegans)
p-MAPK2/3 phosphorylates HSP27 (Drosophila melanogaster)
p-MAPK2/3 phosphorylates HSP27 (Gallus gallus)
p-MAPK2/3 phosphorylates HSP27 (Danio rerio)
p-MAPK2/3 phosphorylates HSP27 (Sus scrofa)
p-MAPK2/3 phosphorylates HSP27 (Bos taurus)
p-MAPK2/3 phosphorylates HSP27 (Rattus norvegicus)
p-MAPK2/3 phosphorylates HSP27 (Mus musculus)
p-MAPK2/3 phosphorylates HSP27 (Homo sapiens)
PAK1-3 phosphorylates VE-cadherin (Caenorhabditis elegans)
PAK1-3 phosphorylates VE-cadherin (Drosophila melanogaster)
PAK1-3 phosphorylates VE-cadherin (Gallus gallus)
PAK1-3 phosphorylates VE-cadherin (Xenopus tropicalis)
PAK1-3 phosphorylates VE-cadherin (Danio rerio)
PAK1-3 phosphorylates VE-cadherin (Sus scrofa)
PAK1-3 phosphorylates VE-cadherin (Bos taurus)
PAK1-3 phosphorylates VE-cadherin (Canis familiaris)
PAK1-3 phosphorylates VE-cadherin (Rattus norvegicus)
PAK1-3 phosphorylates VE-cadherin (Mus musculus)
PAK1-3 phosphorylates VE-cadherin (Homo sapiens)
PAK1-3 autophosphorylates (Caenorhabditis elegans)
PAK1-3 autophosphorylates (Drosophila melanogaster)
PAK1-3 autophosphorylates (Gallus gallus)
PAK1-3 autophosphorylates (Xenopus tropicalis)
PAK1-3 autophosphorylates (Sus scrofa)
PAK1-3 autophosphorylates (Bos taurus)
PAK1-3 autophosphorylates (Canis familiaris)
PAK1-3 autophosphorylates (Rattus norvegicus)
PAK1-3 autophosphorylates (Mus musculus)
PAK1-3 autophosphorylates (Homo sapiens)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Drosophila melanogaster)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Gallus gallus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Sus scrofa)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Bos taurus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Canis familiaris)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Rattus norvegicus)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Mus musculus)
PKC phosphorylates sphingosine kinase 1 (Saccharomyces cerevisiae)
PKC phosphorylates sphingosine kinase 1 (Schizosaccharomyces pombe)
PKC phosphorylates sphingosine kinase 1 (Dictyostelium discoideum)
PKC phosphorylates sphingosine kinase 1 (Caenorhabditis elegans)
PKC phosphorylates sphingosine kinase 1 (Drosophila melanogaster)
PKC phosphorylates sphingosine kinase 1 (Gallus gallus)
PKC phosphorylates sphingosine kinase 1 (Sus scrofa)
PKC phosphorylates sphingosine kinase 1 (Bos taurus)
PKC phosphorylates sphingosine kinase 1 (Canis familiaris)
PKC phosphorylates sphingosine kinase 1 (Rattus norvegicus)
PKC phosphorylates sphingosine kinase 1 (Mus musculus)
PKC phosphorylates sphingosine kinase 1 (Homo sapiens)
p-SPHK1 phosphorylates sphingosine to sphingosine 1-phosphate (Homo sapiens)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Plasmodium falciparum)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Saccharomyces cerevisiae)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Schizosaccharomyces pombe)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Dictyostelium discoideum)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Caenorhabditis elegans)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Drosophila melanogaster)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Gallus gallus)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Sus scrofa)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Bos taurus)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Canis familiaris)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Rattus norvegicus)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Mus musculus)
PIK3C3:PIK3R4 phosphorylates PI to PI3P (Homo sapiens)
PKC phosphorylates NCF1 (Saccharomyces cerevisiae)
PKC phosphorylates NCF1 (Schizosaccharomyces pombe)
PKC phosphorylates NCF1 (Gallus gallus)
PKC phosphorylates NCF1 (Xenopus tropicalis)
PKC phosphorylates NCF1 (Danio rerio)
PKC phosphorylates NCF1 (Sus scrofa)
PKC phosphorylates NCF1 (Bos taurus)
PKC phosphorylates NCF1 (Canis familiaris)
PKC phosphorylates NCF1 (Rattus norvegicus)
PKC phosphorylates NCF1 (Mus musculus)
PKC phosphorylates NCF1 (Homo sapiens)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Gallus gallus)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Xenopus tropicalis)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Sus scrofa)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Bos taurus)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Canis familiaris)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Rattus norvegicus)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Mus musculus)
MAPK11 or MAPK14 phosphorylates NCF1 at Ser345 (Homo sapiens)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Schizosaccharomyces pombe)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Gallus gallus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Xenopus tropicalis)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Sus scrofa)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Bos taurus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Canis familiaris)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Rattus norvegicus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Mus musculus)
MAPK1 or MAPK3 phosphorylates NCF1 at Ser345 (Homo sapiens)
p-S407-STAT6 is phosphorylated at Tyr641 (Dictyostelium discoideum)
p-S407-STAT6 is phosphorylated at Tyr641 (Caenorhabditis elegans)
p-S407-STAT6 is phosphorylated at Tyr641 (Drosophila melanogaster)
p-S407-STAT6 is phosphorylated at Tyr641 (Xenopus tropicalis)
p-S407-STAT6 is phosphorylated at Tyr641 (Danio rerio)
p-S407-STAT6 is phosphorylated at Tyr641 (Sus scrofa)
p-S407-STAT6 is phosphorylated at Tyr641 (Bos taurus)
p-S407-STAT6 is phosphorylated at Tyr641 (Canis familiaris)
p-S407-STAT6 is phosphorylated at Tyr641 (Rattus norvegicus)
p-S407-STAT6 is phosphorylated at Tyr641 (Homo sapiens)
TBK1 phosphorylates STAT6 at Ser407 (Drosophila melanogaster)
TBK1 phosphorylates STAT6 at Ser407 (Xenopus tropicalis)
TBK1 phosphorylates STAT6 at Ser407 (Danio rerio)
TBK1 phosphorylates STAT6 at Ser407 (Sus scrofa)
TBK1 phosphorylates STAT6 at Ser407 (Bos taurus)
TBK1 phosphorylates STAT6 at Ser407 (Rattus norvegicus)
TBK1 phosphorylates STAT6 at Ser407 (Homo sapiens)
TBK1 phosphorylates STAT6 at Ser407 (Mus musculus)
p-S407-STAT6 is phosphorylated at Tyr641 (Mus musculus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Drosophila melanogaster)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Xenopus tropicalis)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Danio rerio)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Sus scrofa)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Bos taurus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Rattus norvegicus)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Homo sapiens)
TBK1 is phosphorylated within STING:TBK1:STAT6 complex (Mus musculus)
Phosphorylation of beta-catenin at Ser552 (Homo sapiens)
Recruitment Tbk1 to dsDNA:Dai followed by its activation (Mus musculus)
Recruitment TBK1 to dsDNA:ZBP1 followed by its activation (Homo sapiens)
Phosphorylation and release of IRF3 (Homo sapiens)
IRF3 is phosphorylated by TBK1 (Sus scrofa)
IRF3 is phosphorylated by TBK1 (Bos taurus)
IRF3 is phosphorylated by TBK1 (Rattus norvegicus)
IRF3 is phosphorylated by TBK1 (Homo sapiens)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Sus scrofa)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Bos taurus)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Rattus norvegicus)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Homo sapiens)
TBK1 is phosphorylated within STING:TBK1:IRF3 complex (Mus musculus)
IRF3 is phosphorylated by TBK1 (Mus musculus)
UCKL1 phosphorylates urindine, cytidine (Saccharomyces cerevisiae)
UCKL1 phosphorylates urindine, cytidine (Schizosaccharomyces pombe)
UCKL1 phosphorylates urindine, cytidine (Dictyostelium discoideum)
UCKL1 phosphorylates urindine, cytidine (Caenorhabditis elegans)
UCKL1 phosphorylates urindine, cytidine (Drosophila melanogaster)
UCKL1 phosphorylates urindine, cytidine (Gallus gallus)
UCKL1 phosphorylates urindine, cytidine (Xenopus tropicalis)
UCKL1 phosphorylates urindine, cytidine (Sus scrofa)
UCKL1 phosphorylates urindine, cytidine (Bos taurus)
UCKL1 phosphorylates urindine, cytidine (Canis familiaris)
UCKL1 phosphorylates urindine, cytidine (Rattus norvegicus)
UCKL1 phosphorylates urindine, cytidine (Mus musculus)
UCKL1 phosphorylates urindine, cytidine (Homo sapiens)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Dictyostelium discoideum)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Caenorhabditis elegans)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Drosophila melanogaster)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Gallus gallus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Xenopus tropicalis)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Danio rerio)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Sus scrofa)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Bos taurus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Canis familiaris)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Rattus norvegicus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Mus musculus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK2] (Homo sapiens)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Gallus gallus)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Xenopus tropicalis)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Danio rerio)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Bos taurus)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Canis familiaris)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Rattus norvegicus)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Mus musculus)
deoxyadenosine or deoxyguanosine + ATP => dAMP or dGMP + ADP (DCK) (Homo sapiens)
Formation of p-STAT1 homodimer (Gallus gallus)
Formation of p-STAT1 homodimer (Xenopus tropicalis)
Formation of p-STAT1 homodimer (Sus scrofa)
Formation of p-STAT1 homodimer (Bos taurus)
Formation of p-STAT1 homodimer (Canis familiaris)
Formation of p-STAT1 homodimer (Rattus norvegicus)
Formation of p-STAT1 homodimer (Mus musculus)
Formation of p-STAT1 homodimer (Homo sapiens)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Plasmodium falciparum)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Saccharomyces cerevisiae)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Schizosaccharomyces pombe)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Dictyostelium discoideum)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Caenorhabditis elegans)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Drosophila melanogaster)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Gallus gallus)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Xenopus tropicalis)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Danio rerio)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Sus scrofa)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Bos taurus)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Canis familiaris)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Rattus norvegicus)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Mus musculus)
NME1:NME3 heterohexamer, NME2P1 phosphorylate NDPs to NTPs (Homo sapiens)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Plasmodium falciparum)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Saccharomyces cerevisiae)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Schizosaccharomyces pombe)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Dictyostelium discoideum)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Caenorhabditis elegans)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Drosophila melanogaster)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Gallus gallus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Xenopus tropicalis)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Danio rerio)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Sus scrofa)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Bos taurus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Canis familiaris)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Rattus norvegicus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Mus musculus)
(d)NDP + ATP <=> (d)NTP + ADP (NME1,2,3) (Homo sapiens)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Gallus gallus)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Xenopus tropicalis)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Danio rerio)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Mus musculus)
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Plasmodium falciparum)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Saccharomyces cerevisiae)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Schizosaccharomyces pombe)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Dictyostelium discoideum)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Caenorhabditis elegans)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Drosophila melanogaster)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Gallus gallus)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Xenopus tropicalis)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Danio rerio)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Sus scrofa)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Bos taurus)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Canis familiaris)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Rattus norvegicus)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Mus musculus)
(d)GMP + ATP <=> (d)GDP + ADP (GUK1) (Homo sapiens)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Plasmodium falciparum)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Saccharomyces cerevisiae)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Schizosaccharomyces pombe)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Dictyostelium discoideum)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Caenorhabditis elegans)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Drosophila melanogaster)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Gallus gallus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Danio rerio)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Sus scrofa)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Bos taurus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Canis familiaris)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Rattus norvegicus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Mus musculus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS2] (Homo sapiens)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Plasmodium falciparum)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Saccharomyces cerevisiae)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Schizosaccharomyces pombe)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Dictyostelium discoideum)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Caenorhabditis elegans)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Drosophila melanogaster)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Gallus gallus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Danio rerio)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Sus scrofa)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Bos taurus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Canis familiaris)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Rattus norvegicus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Mus musculus)
UTP + glutamine + ATP + H2O => CTP + glutamate + ADP + orthophosphate [CTPS] (Homo sapiens)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Plasmodium falciparum)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Saccharomyces cerevisiae)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Schizosaccharomyces pombe)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Dictyostelium discoideum)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Caenorhabditis elegans)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Drosophila melanogaster)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Gallus gallus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Xenopus tropicalis)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Danio rerio)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Sus scrofa)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Bos taurus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Canis familiaris)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Rattus norvegicus)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Mus musculus)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Dictyostelium discoideum)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Caenorhabditis elegans)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Gallus gallus)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Xenopus tropicalis)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Danio rerio)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Sus scrofa)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Bos taurus)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Canis familiaris)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Rattus norvegicus)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Mus musculus)
thymidine + ATP => TMP (deoxythymidine 5'-monophosphate) + ADP [TK1] (Homo sapiens)
dUMP or TMP + ATP <=> dUDP or TDP + ADP [DTYMK] (Homo sapiens)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Plasmodium falciparum)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Saccharomyces cerevisiae)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Schizosaccharomyces pombe)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Dictyostelium discoideum)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Caenorhabditis elegans)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Drosophila melanogaster)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Gallus gallus)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Danio rerio)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Sus scrofa)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Bos taurus)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Canis familiaris)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Rattus norvegicus)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Mus musculus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Gallus gallus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Xenopus tropicalis)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Danio rerio)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Bos taurus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Canis familiaris)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Rattus norvegicus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Mus musculus)
(2'-deoxy)cytidine + ATP => (d)CMP + ADP (DCK) (Homo sapiens)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Dictyostelium discoideum)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Caenorhabditis elegans)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Drosophila melanogaster)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Gallus gallus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Xenopus tropicalis)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Danio rerio)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Sus scrofa)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Bos taurus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Canis familiaris)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Rattus norvegicus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Mus musculus)
cytidine or uridine + ATP => CMP or UMP + ADP [UCK1] (Homo sapiens)
CAD hexamer transforms L-Gln to CAP (Plasmodium falciparum)
CAD hexamer transforms L-Gln to CAP (Saccharomyces cerevisiae)
CAD hexamer transforms L-Gln to CAP (Schizosaccharomyces pombe)
CAD hexamer transforms L-Gln to CAP (Dictyostelium discoideum)
CAD hexamer transforms L-Gln to CAP (Caenorhabditis elegans)
CAD hexamer transforms L-Gln to CAP (Drosophila melanogaster)
CAD hexamer transforms L-Gln to CAP (Xenopus tropicalis)
CAD hexamer transforms L-Gln to CAP (Sus scrofa)
CAD hexamer transforms L-Gln to CAP (Bos taurus)
CAD hexamer transforms L-Gln to CAP (Canis familiaris)
CAD hexamer transforms L-Gln to CAP (Rattus norvegicus)
CAD hexamer transforms L-Gln to CAP (Mus musculus)
CAD hexamer transforms L-Gln to CAP (Homo sapiens)
(d)CMP or UMP + ATP <=> (d)CDP or UDP + ADP (CMPK1) (Homo sapiens)
AMP + ATP <=> ADP + ADP [AK2] (Plasmodium falciparum)
AMP + ATP <=> ADP + ADP [AK2] (Saccharomyces cerevisiae)
AMP + ATP <=> ADP + ADP [AK2] (Schizosaccharomyces pombe)
AMP + ATP <=> ADP + ADP [AK2] (Dictyostelium discoideum)
AMP + ATP <=> ADP + ADP [AK2] (Caenorhabditis elegans)
AMP + ATP <=> ADP + ADP [AK2] (Drosophila melanogaster)
AMP + ATP <=> ADP + ADP [AK2] (Gallus gallus)
AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)
AMP + ATP <=> ADP + ADP [AK2] (Danio rerio)
AMP + ATP <=> ADP + ADP [AK2] (Sus scrofa)
AMP + ATP <=> ADP + ADP [AK2] (Bos taurus)
AMP + ATP <=> ADP + ADP [AK2] (Canis familiaris)
AMP + ATP <=> ADP + ADP [AK2] (Rattus norvegicus)
AMP + ATP <=> ADP + ADP [AK2] (Mus musculus)
AMP + ATP <=> ADP + ADP [AK2] (Homo sapiens)
SHPK phosphorylates Sedo to Sedo7P (Caenorhabditis elegans)
SHPK phosphorylates Sedo to Sedo7P (Gallus gallus)
SHPK phosphorylates Sedo to Sedo7P (Xenopus tropicalis)
SHPK phosphorylates Sedo to Sedo7P (Sus scrofa)
SHPK phosphorylates Sedo to Sedo7P (Bos taurus)
SHPK phosphorylates Sedo to Sedo7P (Canis familiaris)
SHPK phosphorylates Sedo to Sedo7P (Rattus norvegicus)
SHPK phosphorylates Sedo to Sedo7P (Mus musculus)
SHPK phosphorylates Sedo to Sedo7P (Homo sapiens)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Saccharomyces cerevisiae)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Schizosaccharomyces pombe)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Caenorhabditis elegans)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Drosophila melanogaster)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Gallus gallus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Xenopus tropicalis)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Danio rerio)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Sus scrofa)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Bos taurus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Canis familiaris)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Rattus norvegicus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Mus musculus)
PAPSS1,2 transfer PO4(2-) group from ATP to APS to form PAPS (Homo sapiens)
CSNK1D phosphorylates SEC23 (Saccharomyces cerevisiae)
CSNK1D phosphorylates SEC23 (Schizosaccharomyces pombe)
CSNK1D phosphorylates SEC23 (Dictyostelium discoideum)
CSNK1D phosphorylates SEC23 (Bos taurus)
CSNK1D phosphorylates SEC23 (Canis familiaris)
CSNK1D phosphorylates SEC23 (Rattus norvegicus)
CSNK1D phosphorylates SEC23 (Mus musculus)
CSNK1D phosphorylates SEC23 (Homo sapiens)
GBF1 stimulates ARF nucleotide exchange (Plasmodium falciparum)
GBF1 stimulates ARF nucleotide exchange (Saccharomyces cerevisiae)
GBF1 stimulates ARF nucleotide exchange (Schizosaccharomyces pombe)
GBF1 stimulates ARF nucleotide exchange (Dictyostelium discoideum)
GBF1 stimulates ARF nucleotide exchange (Caenorhabditis elegans)
GBF1 stimulates ARF nucleotide exchange (Drosophila melanogaster)
GBF1 stimulates ARF nucleotide exchange (Gallus gallus)
GBF1 stimulates ARF nucleotide exchange (Danio rerio)
GBF1 stimulates ARF nucleotide exchange (Sus scrofa)
GBF1 stimulates ARF nucleotide exchange (Bos taurus)
GBF1 stimulates ARF nucleotide exchange (Canis familiaris)
GBF1 stimulates ARF nucleotide exchange (Rattus norvegicus)
GBF1 stimulates ARF nucleotide exchange (Mus musculus)
GBF1 stimulates ARF nucleotide exchange (Homo sapiens)
SHC1 is phosphorylated downstream of estrogen stimulation of GPER1 (Homo sapiens)
G alpha (s):GTP:SRC catalyzes SRC to p-Y419-SRC (Homo sapiens)
ADRB2 in ADRB2:GRK complex is phosphorylated (Drosophila melanogaster)
ADRB2 in ADRB2:GRK complex is phosphorylated (Gallus gallus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Xenopus tropicalis)
ADRB2 in ADRB2:GRK complex is phosphorylated (Sus scrofa)
ADRB2 in ADRB2:GRK complex is phosphorylated (Bos taurus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Canis familiaris)
ADRB2 in ADRB2:GRK complex is phosphorylated (Rattus norvegicus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Mus musculus)
ADRB2 in ADRB2:GRK complex is phosphorylated (Homo sapiens)
DAG kinase produces phosphatidic acid from DAG (Plasmodium falciparum)
DAG kinase produces phosphatidic acid from DAG (Dictyostelium discoideum)
DAG kinase produces phosphatidic acid from DAG (Caenorhabditis elegans)
DAG kinase produces phosphatidic acid from DAG (Drosophila melanogaster)
DAG kinase produces phosphatidic acid from DAG (Gallus gallus)
DAG kinase produces phosphatidic acid from DAG (Xenopus tropicalis)
DAG kinase produces phosphatidic acid from DAG (Sus scrofa)
DAG kinase produces phosphatidic acid from DAG (Bos taurus)
DAG kinase produces phosphatidic acid from DAG (Canis familiaris)
DAG kinase produces phosphatidic acid from DAG (Rattus norvegicus)
DAG kinase produces phosphatidic acid from DAG (Mus musculus)
DAG kinase produces phosphatidic acid from DAG (Homo sapiens)
PKA phosphorylates PDE4B (Caenorhabditis elegans)
PKA phosphorylates PDE4B (Drosophila melanogaster)
PKA phosphorylates PDE4B (Gallus gallus)
PKA phosphorylates PDE4B (Xenopus tropicalis)
PKA phosphorylates PDE4B (Sus scrofa)
PKA phosphorylates PDE4B (Bos taurus)
PKA phosphorylates PDE4B (Canis familiaris)
PKA phosphorylates PDE4B (Rattus norvegicus)
PKA phosphorylates PDE4B (Mus musculus)
PKA phosphorylates PDE4B (Homo sapiens)
PKA phosphorylates DARPP-32 on Thr34 (Gallus gallus)
PKA phosphorylates DARPP-32 on Thr34 (Xenopus tropicalis)
PKA phosphorylates DARPP-32 on Thr34 (Sus scrofa)
PKA phosphorylates DARPP-32 on Thr34 (Bos taurus)
PKA phosphorylates DARPP-32 on Thr34 (Canis familiaris)
PKA phosphorylates DARPP-32 on Thr34 (Rattus norvegicus)
PKA phosphorylates DARPP-32 on Thr34 (Mus musculus)
PKA phosphorylates DARPP-32 on Thr34 (Homo sapiens)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Caenorhabditis elegans)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Drosophila melanogaster)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Gallus gallus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Danio rerio)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Sus scrofa)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Bos taurus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Canis familiaris)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Rattus norvegicus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Mus musculus)
G protein alpha (i)-SRC complex catalyzes SRC to p-Y419-SRC (Homo sapiens)
PKC (cow) phosphorylates G alpha z (rat) (Bos taurus)
PKC phosphorylates G alpha (z) (Homo sapiens)
ATP binds G-protein beta associated TRiC/CCT (Plasmodium falciparum)
ATP binds G-protein beta associated TRiC/CCT (Saccharomyces cerevisiae)
ATP binds G-protein beta associated TRiC/CCT (Schizosaccharomyces pombe)
ATP binds G-protein beta associated TRiC/CCT (Dictyostelium discoideum)
ATP binds G-protein beta associated TRiC/CCT (Caenorhabditis elegans)
ATP binds G-protein beta associated TRiC/CCT (Drosophila melanogaster)
ATP binds G-protein beta associated TRiC/CCT (Gallus gallus)
ATP binds G-protein beta associated TRiC/CCT (Xenopus tropicalis)
ATP binds G-protein beta associated TRiC/CCT (Danio rerio)
ATP binds G-protein beta associated TRiC/CCT (Sus scrofa)
ATP binds G-protein beta associated TRiC/CCT (Bos taurus)
ATP binds G-protein beta associated TRiC/CCT (Canis familiaris)
ATP binds G-protein beta associated TRiC/CCT (Rattus norvegicus)
ATP binds G-protein beta associated TRiC/CCT (Mus musculus)
ATP binds G-protein beta associated TRiC/CCT (Homo sapiens)
CK2 phosphorylates PDCL (Caenorhabditis elegans)
CK2 phosphorylates PDCL (Drosophila melanogaster)
CK2 phosphorylates PDCL (Sus scrofa)
CK2 phosphorylates PDCL (Bos taurus)
CK2 phosphorylates PDCL (Canis familiaris)
CK2 phosphorylates PDCL (Rattus norvegicus)
CK2 phosphorylates PDCL (Mus musculus)
CK2 phosphorylates PDCL (Homo sapiens)
CERK phosphorylates CERA to form C1P (Caenorhabditis elegans)
CERK phosphorylates CERA to form C1P (Drosophila melanogaster)
CERK phosphorylates CERA to form C1P (Gallus gallus)
CERK phosphorylates CERA to form C1P (Xenopus tropicalis)
CERK phosphorylates CERA to form C1P (Sus scrofa)
CERK phosphorylates CERA to form C1P (Bos taurus)
CERK phosphorylates CERA to form C1P (Canis familiaris)
CERK phosphorylates CERA to form C1P (Rattus norvegicus)
CERK phosphorylates CERA to form C1P (Mus musculus)
CERK phosphorylates CERA to form C1P (Homo sapiens)
CSNK1G2 phosphorylates p-CERT1-2 (Plasmodium falciparum)
CSNK1G2 phosphorylates p-CERT1-2 (Caenorhabditis elegans)
PRKD1,2,3 phosphorylates CERT1-2 (Caenorhabditis elegans)
PRKD1,2,3 phosphorylates CERT1-2 (Drosophila melanogaster)
CSNK1G2 phosphorylates p-CERT1-2 (Drosophila melanogaster)
PRKD1,2,3 phosphorylates CERT1-2 (Danio rerio)
CSNK1G2 phosphorylates p-CERT1-2 (Danio rerio)
PRKD1,2,3 phosphorylates CERT1-2 (Bos taurus)
CSNK1G2 phosphorylates p-CERT1-2 (Bos taurus)
PRKD1,2,3 phosphorylates CERT1-2 (Homo sapiens)
CSNK1G2 phosphorylates p-CERT1-2 (Homo sapiens)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Plasmodium falciparum)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Saccharomyces cerevisiae)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Schizosaccharomyces pombe)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Dictyostelium discoideum)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Caenorhabditis elegans)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Drosophila melanogaster)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Gallus gallus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Xenopus tropicalis)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Sus scrofa)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Bos taurus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Canis familiaris)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Rattus norvegicus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Mus musculus)
ABCC1,ABCG2 transport C18-S1P to extracellular region (Homo sapiens)
SPHK1 phosphorylates sphingoid (Gallus gallus)
SPHK1 phosphorylates sphingoid (Saccharomyces cerevisiae)
SPHK2 phosphorylates sphingoid (Saccharomyces cerevisiae)
SPHK1 phosphorylates sphingoid (Schizosaccharomyces pombe)
SPHK2 phosphorylates sphingoid (Schizosaccharomyces pombe)
SPHK1 phosphorylates sphingoid (Dictyostelium discoideum)
SPHK2 phosphorylates sphingoid (Dictyostelium discoideum)
SPHK1 phosphorylates sphingoid (Caenorhabditis elegans)
SPHK2 phosphorylates sphingoid (Caenorhabditis elegans)
SPHK1 phosphorylates sphingoid (Drosophila melanogaster)
SPHK2 phosphorylates sphingoid (Drosophila melanogaster)
SPHK2 phosphorylates sphingoid (Xenopus tropicalis)
SPHK1 phosphorylates sphingoid (Sus scrofa)
SPHK2 phosphorylates sphingoid (Sus scrofa)
SPHK1 phosphorylates sphingoid (Bos taurus)
SPHK2 phosphorylates sphingoid (Bos taurus)
SPHK1 phosphorylates sphingoid (Canis familiaris)
SPHK2 phosphorylates sphingoid (Canis familiaris)
SPHK1 phosphorylates sphingoid (Rattus norvegicus)
SPHK2 phosphorylates sphingoid (Rattus norvegicus)
SPHK1 phosphorylates sphingoid (Mus musculus)
SPHK2 phosphorylates sphingoid (Mus musculus)
SPHK2 phosphorylates sphingoid (Homo sapiens)
SPHK1 phosphorylates sphingoid (Homo sapiens)
FUK phosphorylates beta-Fuc to Fuc1P (Dictyostelium discoideum)
FUK phosphorylates beta-Fuc to Fuc1P (Caenorhabditis elegans)
FUK phosphorylates beta-Fuc to Fuc1P (Xenopus tropicalis)
FUK phosphorylates beta-Fuc to Fuc1P (Sus scrofa)
FUK phosphorylates beta-Fuc to Fuc1P (Bos taurus)
FUK phosphorylates beta-Fuc to Fuc1P (Canis familiaris)
FUK phosphorylates beta-Fuc to Fuc1P (Rattus norvegicus)
FUK phosphorylates beta-Fuc to Fuc1P (Mus musculus)
FUK phosphorylates beta-Fuc to Fuc1P (Homo sapiens)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Caenorhabditis elegans)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Drosophila melanogaster)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Gallus gallus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Sus scrofa)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Bos taurus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Canis familiaris)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Rattus norvegicus)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Mus musculus)
GNE phosphorylates ManNAc to ManNAc-6-P (Gallus gallus)
GNE phosphorylates ManNAc to ManNAc-6-P (Xenopus tropicalis)
GNE phosphorylates ManNAc to ManNAc-6-P (Danio rerio)
GNE phosphorylates ManNAc to ManNAc-6-P (Sus scrofa)
GNE phosphorylates ManNAc to ManNAc-6-P (Bos taurus)
GNE phosphorylates ManNAc to ManNAc-6-P (Canis familiaris)
GNE phosphorylates ManNAc to ManNAc-6-P (Rattus norvegicus)
GNE phosphorylates ManNAc to ManNAc-6-P (Mus musculus)
GNE phosphorylates ManNAc to ManNAc-6-P (Homo sapiens)
NAGK dimer phosphorylates GlcNAc, GlcNGc to GlcNAc-6-P, GlcNGc-6-P (Homo sapiens)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Gallus gallus)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Xenopus tropicalis)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Danio rerio)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Sus scrofa)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Bos taurus)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Canis familiaris)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Rattus norvegicus)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Mus musculus)
creatine + ATP => phosphocreatine + ADP [CKB,CKM] (Homo sapiens)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Gallus gallus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Xenopus tropicalis)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Danio rerio)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Sus scrofa)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Bos taurus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Canis familiaris)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Rattus norvegicus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Mus musculus)
creatine + ATP => phosphocreatine + ADP [CK octamer] (Homo sapiens)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Saccharomyces cerevisiae)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Schizosaccharomyces pombe)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Dictyostelium discoideum)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Caenorhabditis elegans)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Drosophila melanogaster)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Gallus gallus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Xenopus tropicalis)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Danio rerio)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Sus scrofa)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Bos taurus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Canis familiaris)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Rattus norvegicus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Mus musculus)
FPGS-2 transforms 5-methyl-THF to 5-methyl-THFPG (Homo sapiens)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Plasmodium falciparum)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Saccharomyces cerevisiae)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Schizosaccharomyces pombe)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Dictyostelium discoideum)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Caenorhabditis elegans)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Drosophila melanogaster)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Gallus gallus)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Xenopus tropicalis)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Danio rerio)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Sus scrofa)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Bos taurus)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Canis familiaris)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Rattus norvegicus)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Mus musculus)
MTHFD1 dimer ligates HCOOH to THFPG to form 10-formyl-THFPG (Homo sapiens)
FPGS-2 transforms THF to THFPG (Saccharomyces cerevisiae)
FPGS-2 transforms THF to THFPG (Schizosaccharomyces pombe)
FPGS-2 transforms THF to THFPG (Dictyostelium discoideum)
FPGS-2 transforms THF to THFPG (Caenorhabditis elegans)
FPGS-2 transforms THF to THFPG (Drosophila melanogaster)
FPGS-2 transforms THF to THFPG (Gallus gallus)
FPGS-2 transforms THF to THFPG (Xenopus tropicalis)
FPGS-2 transforms THF to THFPG (Danio rerio)
FPGS-2 transforms THF to THFPG (Sus scrofa)
FPGS-2 transforms THF to THFPG (Bos taurus)
FPGS-2 transforms THF to THFPG (Canis familiaris)
FPGS-2 transforms THF to THFPG (Rattus norvegicus)
FPGS-2 transforms THF to THFPG (Mus musculus)
FPGS-2 transforms THF to THFPG (Homo sapiens)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Gallus gallus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Xenopus tropicalis)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Danio rerio)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Sus scrofa)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Bos taurus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Canis familiaris)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Rattus norvegicus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Mus musculus)
N-acetylaspartylglutamate synthase A ligates NAA, L-Glu forming NAAG (Homo sapiens)
Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by Pstk (Mus musculus)
Ser-tRNA(Sec) is phosphorylated to Sep-tRNA(Sec) by PSTK (Homo sapiens)
APSe is phosphorylated to PAPSe by Kaps (Penicillium chrysogenum)
APSe is phosphorylated to PAPSe by PAPSS1,2 (Homo sapiens)
NMRK2 phosphorylates NR to yield NMN (Dictyostelium discoideum)
NMRK2 phosphorylates NR to yield NMN (Drosophila melanogaster)
NMRK2 phosphorylates NR to yield NMN (Gallus gallus)
NMRK2 phosphorylates NR to yield NMN (Danio rerio)
NMRK2 phosphorylates NR to yield NMN (Sus scrofa)
NMRK2 phosphorylates NR to yield NMN (Bos taurus)
NMRK2 phosphorylates NR to yield NMN (Mus musculus)
NMRK2 phosphorylates NR to yield NMN (Homo sapiens)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Saccharomyces cerevisiae)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Schizosaccharomyces pombe)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Dictyostelium discoideum)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Drosophila melanogaster)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Gallus gallus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Xenopus tropicalis)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Danio rerio)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Sus scrofa)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Bos taurus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Canis familiaris)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Rattus norvegicus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Mus musculus)
NADK:Zn2+ tetramer phosphorylates NAD+ to NADP+ (Homo sapiens)
NMRK1 phosphorylates NR to yield NMN (Dictyostelium discoideum)
NMRK1 phosphorylates NR to yield NMN (Drosophila melanogaster)
NMRK1 phosphorylates NR to yield NMN (Gallus gallus)
NMRK1 phosphorylates NR to yield NMN (Sus scrofa)
NMRK1 phosphorylates NR to yield NMN (Bos taurus)
NMRK1 phosphorylates NR to yield NMN (Canis familiaris)
NMRK1 phosphorylates NR to yield NMN (Rattus norvegicus)
NMRK1 phosphorylates NR to yield NMN (Mus musculus)
NMRK1 phosphorylates NR to yield NMN (Homo sapiens)
NMRK1 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)
NMRK1 phosphorylates NAR to yield NAMN (Drosophila melanogaster)
NMRK1 phosphorylates NAR to yield NAMN (Gallus gallus)
NMRK1 phosphorylates NAR to yield NAMN (Sus scrofa)
NMRK1 phosphorylates NAR to yield NAMN (Bos taurus)
NMRK1 phosphorylates NAR to yield NAMN (Canis familiaris)
NMRK1 phosphorylates NAR to yield NAMN (Rattus norvegicus)
NMRK1 phosphorylates NAR to yield NAMN (Mus musculus)
NMRK1 phosphorylates NAR to yield NAMN (Homo sapiens)
NMRK2 phosphorylates NAR to yield NAMN (Dictyostelium discoideum)
NMRK2 phosphorylates NAR to yield NAMN (Drosophila melanogaster)
NMRK2 phosphorylates NAR to yield NAMN (Gallus gallus)
NMRK2 phosphorylates NAR to yield NAMN (Danio rerio)
NMRK2 phosphorylates NAR to yield NAMN (Sus scrofa)
NMRK2 phosphorylates NAR to yield NAMN (Bos taurus)
NMRK2 phosphorylates NAR to yield NAMN (Mus musculus)
NMRK2 phosphorylates NAR to yield NAMN (Homo sapiens)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Gallus gallus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Xenopus tropicalis)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Sus scrofa)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Bos taurus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Canis familiaris)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Rattus norvegicus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Mus musculus)
CARNS1 transforms ATP, L-His, b-Ala to CARN (Homo sapiens)
Atp7a transfers Cu from Atox1 to Sod3 (Mus musculus)
ATP7A transfers Cu from ATOX1 to SOD3 (Homo sapiens)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Drosophila melanogaster)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Gallus gallus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Sus scrofa)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Bos taurus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Canis familiaris)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Mus musculus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Homo sapiens)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Caenorhabditis elegans)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Drosophila melanogaster)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Gallus gallus)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Xenopus tropicalis)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Danio rerio)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Sus scrofa)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Bos taurus)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Canis familiaris)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Mus musculus)
FGAM + ATP => AIR + ADP + Pi (Saccharomyces cerevisiae)
FGAM + ATP => AIR + ADP + Pi (Schizosaccharomyces pombe)
FGAM + ATP => AIR + ADP + Pi (Dictyostelium discoideum)
FGAM + ATP => AIR + ADP + Pi (Caenorhabditis elegans)
FGAM + ATP => AIR + ADP + Pi (Drosophila melanogaster)
FGAM + ATP => AIR + ADP + Pi (Gallus gallus)
FGAM + ATP => AIR + ADP + Pi (Xenopus tropicalis)
FGAM + ATP => AIR + ADP + Pi (Danio rerio)
FGAM + ATP => AIR + ADP + Pi (Sus scrofa)
FGAM + ATP => AIR + ADP + Pi (Bos taurus)
FGAM + ATP => AIR + ADP + Pi (Canis familiaris)
FGAM + ATP => AIR + ADP + Pi (Mus musculus)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Saccharomyces cerevisiae)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Schizosaccharomyces pombe)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Dictyostelium discoideum)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Caenorhabditis elegans)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Drosophila melanogaster)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Xenopus tropicalis)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Bos taurus)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Canis familiaris)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Mus musculus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Saccharomyces cerevisiae)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Schizosaccharomyces pombe)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Dictyostelium discoideum)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Caenorhabditis elegans)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Drosophila melanogaster)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Gallus gallus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Xenopus tropicalis)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Danio rerio)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Sus scrofa)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Bos taurus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Canis familiaris)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Mus musculus)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Homo sapiens)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Homo sapiens)
FGAM + ATP => AIR + ADP + Pi (Homo sapiens)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Homo sapiens)
5-Phosphoribosylamine + Glycine + ATP => GAR + ADP + Pi (Rattus norvegicus)
FGAR + L-Glutamine + ATP + H2O => FGAM + L-Glutamate + ADP + Pi (Rattus norvegicus)
FGAM + ATP => AIR + ADP + Pi (Rattus norvegicus)
CAIR + Aspartate + ATP => SAICAR + ADP + Pi (Rattus norvegicus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Saccharomyces cerevisiae)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Schizosaccharomyces pombe)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Dictyostelium discoideum)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Caenorhabditis elegans)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Drosophila melanogaster)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Gallus gallus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Xenopus tropicalis)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Danio rerio)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Sus scrofa)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Bos taurus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Canis familiaris)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Mus musculus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Homo sapiens)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Rattus norvegicus)
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Rattus norvegicus)
GLYCTK phosphorylates DGA to 3PDGA (Caenorhabditis elegans)
GLYCTK phosphorylates DGA to 3PDGA (Drosophila melanogaster)
GLYCTK phosphorylates DGA to 3PDGA (Gallus gallus)
GLYCTK phosphorylates DGA to 3PDGA (Danio rerio)
GLYCTK phosphorylates DGA to 3PDGA (Sus scrofa)
GLYCTK phosphorylates DGA to 3PDGA (Bos taurus)
GLYCTK phosphorylates DGA to 3PDGA (Canis familiaris)
GLYCTK phosphorylates DGA to 3PDGA (Rattus norvegicus)
GLYCTK phosphorylates DGA to 3PDGA (Mus musculus)
GLYCTK phosphorylates DGA to 3PDGA (Homo sapiens)
MVD decarboxylates MVA5PP to IPPP (Saccharomyces cerevisiae)
MVD decarboxylates MVA5PP to IPPP (Schizosaccharomyces pombe)
MVD decarboxylates MVA5PP to IPPP (Dictyostelium discoideum)
MVD decarboxylates MVA5PP to IPPP (Caenorhabditis elegans)
MVD decarboxylates MVA5PP to IPPP (Drosophila melanogaster)
MVD decarboxylates MVA5PP to IPPP (Gallus gallus)
MVD decarboxylates MVA5PP to IPPP (Xenopus tropicalis)
MVD decarboxylates MVA5PP to IPPP (Danio rerio)
MVD decarboxylates MVA5PP to IPPP (Sus scrofa)
MVD decarboxylates MVA5PP to IPPP (Bos taurus)
MVD decarboxylates MVA5PP to IPPP (Canis familiaris)
MVD decarboxylates MVA5PP to IPPP (Rattus norvegicus)
MVD decarboxylates MVA5PP to IPPP (Mus musculus)
Mevalonate-5-phosphate is further phosphorylated. (Caenorhabditis elegans)
Mevalonate-5-phosphate is further phosphorylated. (Drosophila melanogaster)
Mevalonate-5-phosphate is further phosphorylated. (Gallus gallus)
Mevalonate-5-phosphate is further phosphorylated. (Danio rerio)
Mevalonate-5-phosphate is further phosphorylated. (Sus scrofa)
Mevalonate-5-phosphate is further phosphorylated. (Bos taurus)
Mevalonate-5-phosphate is further phosphorylated. (Canis familiaris)
Mevalonate-5-phosphate is further phosphorylated. (Rattus norvegicus)
Mevalonate-5-phosphate is further phosphorylated. (Mus musculus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Saccharomyces cerevisiae)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Schizosaccharomyces pombe)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Dictyostelium discoideum)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Caenorhabditis elegans)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Drosophila melanogaster)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Gallus gallus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Danio rerio)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Sus scrofa)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Bos taurus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Canis familiaris)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Rattus norvegicus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Mus musculus)
Mevalonate is phosphorylated to mevalonate-5-phosphate (Homo sapiens)
Mevalonate-5-phosphate is further phosphorylated. (Homo sapiens)
MVD decarboxylates MVA5PP to IPPP (Homo sapiens)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Plasmodium falciparum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Saccharomyces cerevisiae)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Schizosaccharomyces pombe)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Dictyostelium discoideum)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Caenorhabditis elegans)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Drosophila melanogaster)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Gallus gallus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Xenopus tropicalis)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Sus scrofa)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Bos taurus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Canis familiaris)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Rattus norvegicus)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Mus musculus)
ACLY tetramer transforms CIT to Ac-CoA (Schizosaccharomyces pombe)
ACLY tetramer transforms CIT to Ac-CoA (Dictyostelium discoideum)
ACLY tetramer transforms CIT to Ac-CoA (Caenorhabditis elegans)
ACLY tetramer transforms CIT to Ac-CoA (Drosophila melanogaster)
ACLY tetramer transforms CIT to Ac-CoA (Gallus gallus)
ACLY tetramer transforms CIT to Ac-CoA (Xenopus tropicalis)
ACLY tetramer transforms CIT to Ac-CoA (Danio rerio)
ACLY tetramer transforms CIT to Ac-CoA (Sus scrofa)
ACLY tetramer transforms CIT to Ac-CoA (Bos taurus)
ACLY tetramer transforms CIT to Ac-CoA (Canis familiaris)
ACLY tetramer transforms CIT to Ac-CoA (Rattus norvegicus)
ACLY tetramer transforms CIT to Ac-CoA (Mus musculus)
ACLY tetramer transforms CIT to Ac-CoA (Homo sapiens)
acetyl-CoA + bicarbonate + ATP => malonyl-CoA + H2O + ADP + orthophosphate (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Dictyostelium discoideum)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Gallus gallus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Xenopus tropicalis)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Bos taurus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Mus musculus)
Phosphorylation of PF2K-Pase by PKA catalytic subunit (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 2,6-bisphosphate + ADP (Homo sapiens)
GALK1 phosphorylates Gal to Gal1P (Gallus gallus)
GALK1 phosphorylates Gal to Gal1P (Xenopus tropicalis)
GALK1 phosphorylates Gal to Gal1P (Danio rerio)
GALK1 phosphorylates Gal to Gal1P (Sus scrofa)
GALK1 phosphorylates Gal to Gal1P (Bos taurus)
GALK1 phosphorylates Gal to Gal1P (Canis familiaris)
GALK1 phosphorylates Gal to Gal1P (Rattus norvegicus)
GALK1 phosphorylates Gal to Gal1P (Homo sapiens)
GALK1 phosphorylates Gal to Gal1P (Mus musculus)
glycogen phosphorylase (PYGB) dimer b + 2 ATP => glycogen phosphorylase (PYGB) dimer a + 2 ADP (Homo sapiens)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Caenorhabditis elegans)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Drosophila melanogaster)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Sus scrofa)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Bos taurus)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Canis familiaris)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Rattus norvegicus)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Mus musculus)
glycogen phosphorylase (PYGM) dimer b + 2 ATP => glycogen phosphorylase (PYGM) dimer a + 2 ADP (Homo sapiens)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Xenopus tropicalis)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Sus scrofa)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Bos taurus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Canis familiaris)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Rattus norvegicus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Mus musculus)
glycogen phosphorylase (PYGL) dimer b + 2 ATP => glycogen phosphorylase (PYGL) dimer a + 2 ADP (Homo sapiens)
NEK1 phosphorylates ME1 (Gallus gallus)
NEK1 phosphorylates ME1 (Sus scrofa)
NEK1 phosphorylates ME1 (Bos taurus)
NEK1 phosphorylates ME1 (Canis familiaris)
NEK1 phosphorylates ME1 (Rattus norvegicus)
NEK1 phosphorylates ME1 (Mus musculus)
NEK1 phosphorylates ME1 (Homo sapiens)
SRXN1 reduces hyperoxidized PRDX1 dimer (Saccharomyces cerevisiae)
SRXN1 reduces hyperoxidized PRDX1 dimer (Schizosaccharomyces pombe)
SRXN1 reduces hyperoxidized PRDX1 dimer (Drosophila melanogaster)
SRXN1 reduces hyperoxidized PRDX1 dimer (Gallus gallus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Sus scrofa)
SRXN1 reduces hyperoxidized PRDX1 dimer (Bos taurus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Canis familiaris)
SRXN1 reduces hyperoxidized PRDX1 dimer (Rattus norvegicus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Mus musculus)
SRXN1 reduces hyperoxidized PRDX1 dimer (Homo sapiens)
CK2 phosphorylates Nrf2 (Mus musculus)
CK2 phosphorylates NFE2L2 (Homo sapiens)
PKC phosphorylates Nrf2 (Rattus norvegicus)
PKC phosphorylates NFE2L2 (Homo sapiens)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Dictyostelium discoideum)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Xenopus tropicalis)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Sus scrofa)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Bos taurus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Canis familiaris)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Rattus norvegicus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Mus musculus)
SPAST (spastin) mediates the severing of microtubules at chromosome attachment sites (Homo sapiens)
VPS4 mediates disassembly of ESCRTIII subunits to promote sealing of holes in the nuclear envelope (Homo sapiens)
CDK1 phosphorylates LBR (Gallus gallus)
CDK1 phosphorylates LBR (Xenopus tropicalis)
CDK1 phosphorylates LBR (Danio rerio)
CDK1 phosphorylates LBR (Sus scrofa)
CDK1 phosphorylates LBR (Bos taurus)
CDK1 phosphorylates LBR (Canis familiaris)
CDK1 phosphorylates LBR (Rattus norvegicus)
CDK1 phosphorylates LBR (Mus musculus)
CDK1 phosphorylates LBR (Homo sapiens)
LYN phosphorylates CD22 (Sus scrofa)
LYN phosphorylates CD22 (Bos taurus)
LYN phosphorylates CD22 (Canis familiaris)
LYN phosphorylates CD22 (Rattus norvegicus)
LYN phosphorylates CD22 (Mus musculus)
LYN phosphorylates CD22 (Homo sapiens)
Activated IKK phosphorylates I-kappaB (Drosophila melanogaster)
Activated IKK phosphorylates I-kappaB (Sus scrofa)
Activated IKK phosphorylates I-kappaB (Bos taurus)
Activated IKK phosphorylates I-kappaB (Canis familiaris)
Activated IKK phosphorylates I-kappaB (Rattus norvegicus)
Activated IKK phosphorylates I-kappaB (Mus musculus)
Activated IKK phosphorylates I-kappaB (Homo sapiens)
PRKCB (PKC-beta) phosphorylates CARMA1 (Gallus gallus)
PRKCB (PKC-beta) phosphorylates CARMA1 (Xenopus tropicalis)
PRKCB (PKC-beta) phosphorylates CARMA1 (Bos taurus)
PRKCB (PKC-beta) phosphorylates CARMA1 (Canis familiaris)
PRKCB (PKC-beta) phosphorylates CARMA1 (Rattus norvegicus)
PRKCB (PKC-beta) phosphorylates CARMA1 (Mus musculus)
PRKCB (PKC-beta) phosphorylates CARMA1 (Homo sapiens)
TAK1 associated with the CBM complex phosphorylates IKKbeta (Homo sapiens)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Saccharomyces cerevisiae)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Schizosaccharomyces pombe)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Dictyostelium discoideum)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Gallus gallus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Xenopus tropicalis)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Danio rerio)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Sus scrofa)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Bos taurus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Canis familiaris)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Rattus norvegicus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Mus musculus)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Homo sapiens)
PI(3,4,5)P3 (PIP3) binds DAPP1 (BAM32) and DAPP1 is phosphorylated (Plasmodium falciparum)
NEK6 and NEK7 phosphorylate EML4 (Caenorhabditis elegans)
NEK6 and NEK7 phosphorylate EML4 (Gallus gallus)
NEK6 and NEK7 phosphorylate EML4 (Sus scrofa)
NEK6 and NEK7 phosphorylate EML4 (Bos taurus)
NEK6 and NEK7 phosphorylate EML4 (Canis familiaris)
NEK6 and NEK7 phosphorylate EML4 (Homo sapiens)
PLK1 phosphorylates NUDC (Plasmodium falciparum)
PLK1 phosphorylates NUDC (Schizosaccharomyces pombe)
PLK1 phosphorylates NUDC (Dictyostelium discoideum)
PLK1 phosphorylates NUDC (Caenorhabditis elegans)
PLK1 phosphorylates NUDC (Drosophila melanogaster)
PLK1 phosphorylates NUDC (Gallus gallus)
PLK1 phosphorylates NUDC (Xenopus tropicalis)
PLK1 phosphorylates NUDC (Danio rerio)
PLK1 phosphorylates NUDC (Sus scrofa)
PLK1 phosphorylates NUDC (Bos taurus)
PLK1 phosphorylates NUDC (Canis familiaris)
PLK1 phosphorylates NUDC (Mus musculus)
PLK1 phosphorylates NUDC (Homo sapiens)
PLK1 phosphorylates NUDC (Rattus norvegicus)
Plk1-mediated phosphorylation of Nlp (Gallus gallus)
Plk1-mediated phosphorylation of Nlp (Xenopus tropicalis)
Plk1-mediated phosphorylation of Nlp (Sus scrofa)
Plk1-mediated phosphorylation of Nlp (Bos taurus)
Plk1-mediated phosphorylation of Nlp (Canis familiaris)
Plk1-mediated phosphorylation of Nlp (Rattus norvegicus)
Plk1-mediated phosphorylation of Nlp (Mus musculus)
Plk1-mediated phosphorylation of Nlp (Homo sapiens)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Xenopus tropicalis)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Sus scrofa)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Bos taurus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Canis familiaris)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Rattus norvegicus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Mus musculus)
Mitotic phosphorylation-induced dissociation of GTSE1 from microtubule plus ends (Homo sapiens)
TPX2 promotes AURKA autophosphorylation (Gallus gallus)
TPX2 promotes AURKA autophosphorylation (Xenopus tropicalis)
TPX2 promotes AURKA autophosphorylation (Sus scrofa)
TPX2 promotes AURKA autophosphorylation (Bos taurus)
TPX2 promotes AURKA autophosphorylation (Canis familiaris)
TPX2 promotes AURKA autophosphorylation (Rattus norvegicus)
TPX2 promotes AURKA autophosphorylation (Mus musculus)
TPX2 promotes AURKA autophosphorylation (Homo sapiens)
PLK1 phosphorylates OPTN (Drosophila melanogaster)
PLK1 phosphorylates OPTN (Gallus gallus)
PLK1 phosphorylates OPTN (Xenopus tropicalis)
PLK1 phosphorylates OPTN (Danio rerio)
PLK1 phosphorylates OPTN (Sus scrofa)
PLK1 phosphorylates OPTN (Bos taurus)
PLK1 phosphorylates OPTN (Canis familiaris)
PLK1 phosphorylates OPTN (Rattus norvegicus)
PLK1 phosphorylates OPTN (Mus musculus)
PLK1 phosphorylates OPTN (Homo sapiens)
AURKA phosphorylates PHLDA1 (Gallus gallus)
AURKA phosphorylates PHLDA1 (Xenopus tropicalis)
AURKA phosphorylates PHLDA1 (Danio rerio)
AURKA phosphorylates PHLDA1 (Sus scrofa)
AURKA phosphorylates PHLDA1 (Bos taurus)
AURKA phosphorylates PHLDA1 (Canis familiaris)
AURKA phosphorylates PHLDA1 (Rattus norvegicus)
AURKA phosphorylates PHLDA1 (Mus musculus)
AURKA phosphorylates PHLDA1 (Homo sapiens)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Caenorhabditis elegans)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Drosophila melanogaster)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Gallus gallus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Xenopus tropicalis)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Danio rerio)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Sus scrofa)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Bos taurus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Canis familiaris)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Rattus norvegicus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Mus musculus)
MAPK3-3 or MAPK1 phosphorylate GORASP2 (Homo sapiens)
PLK1 phosphorylates GORASP1 (Plasmodium falciparum)
PLK1 phosphorylates GORASP1 (Schizosaccharomyces pombe)
PLK1 phosphorylates GORASP1 (Dictyostelium discoideum)
PLK1 phosphorylates GORASP1 (Caenorhabditis elegans)
PLK1 phosphorylates GORASP1 (Drosophila melanogaster)
PLK1 phosphorylates GORASP1 (Gallus gallus)
PLK1 phosphorylates GORASP1 (Xenopus tropicalis)
PLK1 phosphorylates GORASP1 (Sus scrofa)
PLK1 phosphorylates GORASP1 (Bos taurus)
PLK1 phosphorylates GORASP1 (Canis familiaris)
PLK1 phosphorylates GORASP1 (Rattus norvegicus)
PLK1 phosphorylates GORASP1 (Mus musculus)
Phosphorylation of Gorasp1, Golga2 and RAB1A by CDK1:CCNB (Homo sapiens)
Phosphorylation of GORASP1, GOLGA2 and RAB1A by CDK1:CCNB (Homo sapiens)
PLK1 phosphorylates GORASP1 (Homo sapiens)
PLK1 phosphorylates GORASP1 (Saccharomyces cerevisiae)
NEK6/NEK7 phosphorylates NUP98 (Gallus gallus)
NEK6/NEK7 phosphorylates NUP98 (Sus scrofa)
NEK6/NEK7 phosphorylates NUP98 (Bos taurus)
NEK6/NEK7 phosphorylates NUP98 (Canis familiaris)
CDK1 phosphorylates NUP98 (Drosophila melanogaster)
CDK1 phosphorylates NUP98 (Gallus gallus)
CDK1 phosphorylates NUP98 (Xenopus tropicalis)
CDK1 phosphorylates NUP98 (Sus scrofa)
CDK1 phosphorylates NUP98 (Bos taurus)
CDK1 phosphorylates NUP98 (Canis familiaris)
CDK1 phosphorylates NUP98 (Rattus norvegicus)
CDK1 phosphorylates NUP98 (Mus musculus)
CDK1 phosphorylates NUP98 (Homo sapiens)
NEK6/NEK7 phosphorylates NUP98 (Homo sapiens)
NEK9 phosphorylates NEK6/NEK7 (Caenorhabditis elegans)
NEK9 phosphorylates NEK6/NEK7 (Gallus gallus)
NEK9 phosphorylates NEK6/NEK7 (Sus scrofa)
NEK9 phosphorylates NEK6/NEK7 (Bos taurus)
NEK9 phosphorylates NEK6/NEK7 (Canis familiaris)
NEK9 phosphorylates NEK6/NEK7 (Homo sapiens)
PLK1 phosphorylates NEK9 (Caenorhabditis elegans)
PLK1 phosphorylates NEK9 (Gallus gallus)
PLK1 phosphorylates NEK9 (Sus scrofa)
PLK1 phosphorylates NEK9 (Bos taurus)
PLK1 phosphorylates NEK9 (Canis familiaris)
PLK1 phosphorylates NEK9 (Rattus norvegicus)
PLK1 phosphorylates NEK9 (Mus musculus)
PLK1 phosphorylates NEK9 (Homo sapiens)
CDK1:CCNB phosphorylates NEK9 (Caenorhabditis elegans)
CDK1:CCNB phosphorylates NEK9 (Gallus gallus)
CDK1:CCNB phosphorylates NEK9 (Sus scrofa)
CDK1:CCNB phosphorylates NEK9 (Bos taurus)
CDK1:CCNB phosphorylates NEK9 (Canis familiaris)
CDK1:CCNB phosphorylates NEK9 (Rattus norvegicus)
CDK1:CCNB phosphorylates NEK9 (Mus musculus)
CDK1:CCNB phosphorylates NEK9 (Homo sapiens)
PKC autophosphorylates (Schizosaccharomyces pombe)
PKC autophosphorylates (Dictyostelium discoideum)
PKC autophosphorylates (Caenorhabditis elegans)
PKC autophosphorylates (Drosophila melanogaster)
PKC autophosphorylates (Gallus gallus)
PKC autophosphorylates (Xenopus tropicalis)
PKC autophosphorylates (Danio rerio)
PKC autophosphorylates (Sus scrofa)
PKC autophosphorylates (Bos taurus)
PKC autophosphorylates (Canis familiaris)
PKC autophosphorylates (Rattus norvegicus)
PKC autophosphorylates (Mus musculus)
PKC autophosphorylates (Homo sapiens)
PDK1 phosphorylates PKC (Schizosaccharomyces pombe)
PDK1 phosphorylates PKC (Dictyostelium discoideum)
PDK1 phosphorylates PKC (Caenorhabditis elegans)
PDK1 phosphorylates PKC (Drosophila melanogaster)
PDK1 phosphorylates PKC (Gallus gallus)
PDK1 phosphorylates PKC (Xenopus tropicalis)
PDK1 phosphorylates PKC (Danio rerio)
PDK1 phosphorylates PKC (Sus scrofa)
PDK1 phosphorylates PKC (Bos taurus)
PDK1 phosphorylates PKC (Canis familiaris)
PDK1 phosphorylates PKC (Rattus norvegicus)
PDK1 phosphorylates PKC (Mus musculus)
PDK1 phosphorylates PKC (Homo sapiens)
PDK1 phosphorylates PKC (Saccharomyces cerevisiae)
PKC autophosphorylates (Saccharomyces cerevisiae)
PLK1 phosphorylates FIRRM at S43 (Gallus gallus)
PLK1 phosphorylates FIRRM at S43 (Danio rerio)
PLK1 phosphorylates FIRRM at S43 (Sus scrofa)
PLK1 phosphorylates FIRRM at S43 (Bos taurus)
PLK1 phosphorylates FIRRM at S43 (Canis familiaris)
PLK1 phosphorylates FIRRM at S43 (Rattus norvegicus)
PLK1 phosphorylates FIRRM at S43 (Mus musculus)
PLK1 phosphorylates FIRRM at S43 (Homo sapiens)
PLK1 phosphorylates FIRMM at S744 (Gallus gallus)
PLK1 phosphorylates FIRMM at S744 (Danio rerio)
PLK1 phosphorylates FIRMM at S744 (Sus scrofa)
PLK1 phosphorylates FIRMM at S744 (Bos taurus)
PLK1 phosphorylates FIRMM at S744 (Canis familiaris)
PLK1 phosphorylates FIRMM at S744 (Rattus norvegicus)
PLK1 phosphorylates FIRMM at S744 (Mus musculus)
PLK1 phosphorylates FIRMM at S744 (Homo sapiens)
Phosphorylation of cohesin by PLK1 at centromeres (Gallus gallus)
Phosphorylation of cohesin by PLK1 at centromeres (Xenopus tropicalis)
Phosphorylation of cohesin by PLK1 at centromeres (Sus scrofa)
Phosphorylation of cohesin by PLK1 at centromeres (Bos taurus)
Phosphorylation of cohesin by PLK1 at centromeres (Canis familiaris)
Phosphorylation of cohesin by PLK1 at centromeres (Rattus norvegicus)
Phosphorylation of cohesin by PLK1 at centromeres (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Gallus gallus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Xenopus tropicalis)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Sus scrofa)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Rattus norvegicus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at centromeres (Homo sapiens)
Phosphorylation of cohesin by PLK1 at centromeres (Homo sapiens)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Saccharomyces cerevisiae)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Schizosaccharomyces pombe)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Dictyostelium discoideum)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Caenorhabditis elegans)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Drosophila melanogaster)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Gallus gallus)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Xenopus tropicalis)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Danio rerio)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Sus scrofa)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Bos taurus)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Canis familiaris)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Rattus norvegicus)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Caenorhabditis elegans)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Drosophila melanogaster)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Gallus gallus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Xenopus tropicalis)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Danio rerio)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Sus scrofa)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Bos taurus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Canis familiaris)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Rattus norvegicus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Mus musculus)
CDK1 phosphorylates CDCA5 (Sororin) at chromosomal arms (Homo sapiens)
Phosphorylation of cohesin by PLK1 at chromosomal arms (Homo sapiens)
Cdk1 phosphorylates condensin I (Xenopus laevis)
CDK1 phosphorylates condensin I (Homo sapiens)
CK2 phosphorylates condensin I subunits (Plasmodium falciparum)
CK2 phosphorylates condensin I subunits (Schizosaccharomyces pombe)
CK2 phosphorylates condensin I subunits (Dictyostelium discoideum)
CK2 phosphorylates condensin I subunits (Drosophila melanogaster)
CK2 phosphorylates condensin I subunits (Sus scrofa)
CK2 phosphorylates condensin I subunits (Bos taurus)
CK2 phosphorylates condensin I subunits (Canis familiaris)
CK2 phosphorylates condensin I subunits (Rattus norvegicus)
CK2 phosphorylates condensin I subunits (Mus musculus)
CK2 phosphorylates condensin I subunits (Homo sapiens)
CK2 phosphorylates condensin I subunits (Saccharomyces cerevisiae)
Phosphorylation of LAT by p-SYK (Sus scrofa)
Phosphorylation of LAT by p-SYK (Bos taurus)
Phosphorylation of LAT by p-SYK (Canis familiaris)
Phosphorylation of LAT by p-SYK (Rattus norvegicus)
Phosphorylation of LAT by p-SYK (Mus musculus)
Phosphorylation of LAT by p-SYK (Homo sapiens)
Autophosphorylation of BTK/ITK (Drosophila melanogaster)
Autophosphorylation of BTK/ITK (Gallus gallus)
Autophosphorylation of BTK/ITK (Xenopus tropicalis)
Autophosphorylation of BTK/ITK (Sus scrofa)
Autophosphorylation of BTK/ITK (Bos taurus)
Autophosphorylation of BTK/ITK (Canis familiaris)
Autophosphorylation of BTK/ITK (Rattus norvegicus)
Autophosphorylation of BTK/ITK (Mus musculus)
Phosphorylation of TEC kinases by p-SYK (Sus scrofa)
Phosphorylation of TEC kinases by p-SYK (Bos taurus)
Phosphorylation of TEC kinases by p-SYK (Canis familiaris)
Phosphorylation of TEC kinases by p-SYK (Rattus norvegicus)
Phosphorylation of TEC kinases by p-SYK (Mus musculus)
Phosphorylation of TEC kinases by p-SYK (Homo sapiens)
Autophosphorylation of BTK/ITK (Homo sapiens)
Phosphorylation of PLC-gamma (Homo sapiens)
Phosphorylation of MEK4 by MEKK1 (Gallus gallus)
Phosphorylation of MEK4 by MEKK1 (Xenopus tropicalis)
Phosphorylation of MEK4 by MEKK1 (Sus scrofa)
Phosphorylation of MEK4 by MEKK1 (Bos taurus)
Phosphorylation of MEK4 by MEKK1 (Canis familiaris)
Phosphorylation of MEK4 by MEKK1 (Rattus norvegicus)
Phosphorylation of MEK4 by MEKK1 (Mus musculus)
Phosphorylation of MEK4 by MEKK1 (Homo sapiens)
Phosphorylation of MEK4 by MEKK1 (Dictyostelium discoideum)
Re-acidification of acetylcholine transport vesicles (Homo sapiens)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR3 complex (Homo sapiens)
TBK1 is phosphorylated within the activated TLR3 complex (Homo sapiens)
IKKε (IKBKE) is phosphorylated within the activated TLR3 complex (Homo sapiens)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Gallus gallus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Xenopus tropicalis)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Danio rerio)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Sus scrofa)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Rattus norvegicus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Mus musculus)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Homo sapiens)
ATP7A transports cytosolic Cu2+ to phagosomal lumen (Canis familiaris)
PLK2 phosphorylates NPM1 (Gallus gallus)
PLK2 phosphorylates NPM1 (Xenopus tropicalis)
PLK2 phosphorylates NPM1 (Sus scrofa)
PLK2 phosphorylates NPM1 (Bos taurus)
PLK2 phosphorylates NPM1 (Canis familiaris)
PLK2 phosphorylates NPM1 (Rattus norvegicus)
PLK2 phosphorylates NPM1 (Mus musculus)
PLK2 phosphorylates NPM1 (Homo sapiens)
PLK2 phosphorylates CENPJ (Gallus gallus)
PLK2 phosphorylates CENPJ (Danio rerio)
PLK2 phosphorylates CENPJ (Sus scrofa)
PLK2 phosphorylates CENPJ (Bos taurus)
PLK2 phosphorylates CENPJ (Canis familiaris)
PLK2 phosphorylates CENPJ (Rattus norvegicus)
PLK2 phosphorylates CENPJ (Mus musculus)
PLK2 phosphorylates CENPJ (Homo sapiens)
MAP3K5 (ASK1) phosphorylates Map2k4(Sek1) (Homo sapiens)
MAP3K5 (ASK1) phosphorylates MAP2K4 (SEK1) (Homo sapiens)
BRAF and RAF fusion mutant dimers are phosphorylated (Homo sapiens)
p-BRAF and RAF fusion dimers phosphorylate MAP2Ks (Homo sapiens)
MAPKs are phosphorylated downstream of BRAF and RAF fusion dimers (Homo sapiens)
RAF1 mutant complexes phosphorylate MAP2K dimer (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of RAF1 mutants (Homo sapiens)
Phosphorylation of RAF1 mutants (Homo sapiens)
RAF is paradoxically phosphorylated downstream of kinase-inactive RAF (Homo sapiens)
RAS:GTP:inactive p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of inactive BRAF mutants (Homo sapiens)
MAP2K mutants constitutively phosphorylate MAPKs (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of moderate kinase activity BRAF mutants (Homo sapiens)
RAF is phosphorylated downstream of moderate kinase activity BRAF mutants (Homo sapiens)
RAS:GTP:moderate kinase activity p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of high kinase activity BRAF mutants (Homo sapiens)
High kinase activity BRAF complexes phosphorylate MAP2Ks (Homo sapiens)
RAF is phosphorylated downstream of oncogenic RAS (Homo sapiens)
Mutant RAS:p-RAF complexes phosphorylate MAP2Ks (Homo sapiens)
Activated MAP2Ks phosphorylate MAPKs downstream of oncogenic RAS (Homo sapiens)
PTPN11 is phosphorylated (Gallus gallus)
PTPN11 is phosphorylated (Xenopus tropicalis)
PTPN11 is phosphorylated (Danio rerio)
PTPN11 is phosphorylated (Sus scrofa)
PTPN11 is phosphorylated (Bos taurus)
PTPN11 is phosphorylated (Canis familiaris)
PTPN11 is phosphorylated (Rattus norvegicus)
PTPN11 is phosphorylated (Mus musculus)
PTPN11 is phosphorylated (Homo sapiens)
Serine phosphorylation of STATs (Gallus gallus)
Serine phosphorylation of STATs (Xenopus tropicalis)
Serine phosphorylation of STATs (Danio rerio)
Serine phosphorylation of STATs (Sus scrofa)
Serine phosphorylation of STATs (Bos taurus)
Serine phosphorylation of STATs (Canis familiaris)
Serine phosphorylation of STATs (Rattus norvegicus)
Serine phosphorylation of STATs (Mus musculus)
Serine phosphorylation of STATs (Homo sapiens)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Gallus gallus)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Xenopus tropicalis)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Danio rerio)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Sus scrofa)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Bos taurus)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Canis familiaris)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Rattus norvegicus)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Mus musculus)
IL6ST is tyrosine phosphorylated (Gallus gallus)
IL6ST is tyrosine phosphorylated (Xenopus tropicalis)
IL6ST is tyrosine phosphorylated (Danio rerio)
IL6ST is tyrosine phosphorylated (Sus scrofa)
IL6ST is tyrosine phosphorylated (Bos taurus)
IL6ST is tyrosine phosphorylated (Canis familiaris)
IL6ST is tyrosine phosphorylated (Rattus norvegicus)
IL6ST is tyrosine phosphorylated (Mus musculus)
JAK activation (Gallus gallus)
JAK activation (Xenopus tropicalis)
JAK activation (Danio rerio)
JAK activation (Sus scrofa)
JAK activation (Bos taurus)
JAK activation (Canis familiaris)
JAK activation (Rattus norvegicus)
JAK activation (Mus musculus)
JAK activation (Homo sapiens)
IL6ST is tyrosine phosphorylated (Homo sapiens)
Tyrosine phosphorylation of STAT1, STAT3 by IL6 receptor (Homo sapiens)
ULK1 phosphorylates RIPK1 at S357 (Gallus gallus)
ULK1 phosphorylates RIPK1 at S357 (Xenopus tropicalis)
ULK1 phosphorylates RIPK1 at S357 (Sus scrofa)
ULK1 phosphorylates RIPK1 at S357 (Bos taurus)
ULK1 phosphorylates RIPK1 at S357 (Canis familiaris)
ULK1 phosphorylates RIPK1 at S357 (Rattus norvegicus)
ULK1 phosphorylates RIPK1 at S357 (Mus musculus)
ULK1 phosphorylates RIPK1 at S357 (Homo sapiens)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Sus scrofa)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Bos taurus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Canis familiaris)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Rattus norvegicus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Mus musculus)
CHUK, IKBKB phosphorylate RIPK1 at S25 (Homo sapiens)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Gallus gallus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Sus scrofa)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Bos taurus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Canis familiaris)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Rattus norvegicus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Mus musculus)
TBK1, IKBKE phosphorylate RIPK1 at T189 (Homo sapiens)
MAPKAPK2 phosphorylates RIPK1 at S320 (Gallus gallus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Sus scrofa)
MAPKAPK2 phosphorylates RIPK1 at S320 (Bos taurus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Rattus norvegicus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Mus musculus)
MAPKAPK2 phosphorylates RIPK1 at S320 (Homo sapiens)
CHUK, IKBKB phosphorylate CYLD at S418 (Drosophila melanogaster)
CHUK, IKBKB phosphorylate CYLD at S418 (Sus scrofa)
CHUK, IKBKB phosphorylate CYLD at S418 (Bos taurus)
CHUK, IKBKB phosphorylate CYLD at S418 (Canis familiaris)
CHUK, IKBKB phosphorylate CYLD at S418 (Rattus norvegicus)
CHUK, IKBKB phosphorylate CYLD at S418 (Mus musculus)
CHUK, IKBKB phosphorylate CYLD at S418 (Homo sapiens)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Drosophila melanogaster)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Gallus gallus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Xenopus tropicalis)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Danio rerio)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Sus scrofa)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Bos taurus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Canis familiaris)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Rattus norvegicus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Mus musculus)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Homo sapiens)
PI3K catalyses the phosphorylation of PIP2 to PIP3 (Caenorhabditis elegans)
Phosphorylation of PLCgamma by PDGFR (Drosophila melanogaster)
Phosphorylation of PLCgamma by PDGFR (Gallus gallus)
Phosphorylation of PLCgamma by PDGFR (Xenopus tropicalis)
Phosphorylation of PLCgamma by PDGFR (Danio rerio)
Phosphorylation of PLCgamma by PDGFR (Sus scrofa)
Phosphorylation of PLCgamma by PDGFR (Bos taurus)
Phosphorylation of PLCgamma by PDGFR (Canis familiaris)
Phosphorylation of PLCgamma by PDGFR (Rattus norvegicus)
Phosphorylation of PLCgamma by PDGFR (Mus musculus)
Phosphorylation of PLCgamma by PDGFR (Homo sapiens)
Phosphorylation of PLCgamma by PDGFR (Caenorhabditis elegans)
Activation of Src (Drosophila melanogaster)
Activation of Src (Gallus gallus)
Activation of Src (Danio rerio)
Activation of Src (Sus scrofa)
Activation of Src (Bos taurus)
Activation of Src (Canis familiaris)
Activation of Src (Rattus norvegicus)
Activation of Src (Mus musculus)
Activation of Src (Homo sapiens)
Activation of Src (Caenorhabditis elegans)
SRC phosphorylates PTK2 (Caenorhabditis elegans)
SRC phosphorylates PTK2 (Sus scrofa)
SRC phosphorylates PTK2 (Bos taurus)
SRC phosphorylates PTK2 (Canis familiaris)
SRC phosphorylates PTK2 (Rattus norvegicus)
SRC phosphorylates PTK2 (Mus musculus)
SRC phosphorylates PTK2 (Homo sapiens)
MET phosphorylates PTK2 (Caenorhabditis elegans)
MET phosphorylates PTK2 (Sus scrofa)
MET phosphorylates PTK2 (Bos taurus)
MET phosphorylates PTK2 (Canis familiaris)
MET phosphorylates PTK2 (Rattus norvegicus)
MET phosphorylates PTK2 (Mus musculus)
MET phosphorylates PTK2 (Homo sapiens)
PTK2 autophosphorylates (Caenorhabditis elegans)
PTK2 autophosphorylates (Bos taurus)
PTK2 autophosphorylates (Canis familiaris)
PTK2 autophosphorylates (Rattus norvegicus)
PTK2 autophosphorylates (Mus musculus)
PTK2 autophosphorylates (Homo sapiens)
PTK2 autophosphorylates (Gallus gallus)
MET phosphorylates PTK2 (Gallus gallus)
SRC phosphorylates PTK2 (Gallus gallus)
MET bound PI3K generates PIP3 (Caenorhabditis elegans)
MET bound PI3K generates PIP3 (Xenopus tropicalis)
MET bound PI3K generates PIP3 (Sus scrofa)
MET bound PI3K generates PIP3 (Bos taurus)
MET bound PI3K generates PIP3 (Canis familiaris)
MET bound PI3K generates PIP3 (Rattus norvegicus)
MET bound PI3K generates PIP3 (Mus musculus)
MET bound PI3K generates PIP3 (Homo sapiens)
MET bound PI3K generates PIP3 (Gallus gallus)
MET phosphorylates CBL (Caenorhabditis elegans)
MET phosphorylates CBL (Xenopus tropicalis)
MET phosphorylates CBL (Danio rerio)
MET phosphorylates CBL (Sus scrofa)
MET phosphorylates CBL (Bos taurus)
MET phosphorylates CBL (Canis familiaris)
MET phosphorylates CBL (Rattus norvegicus)
MET phosphorylates CBL (Mus musculus)
MET phosphorylates CBL (Homo sapiens)
MET phosphorylates CBL (Gallus gallus)
MET phosphorylates GAB1 (Caenorhabditis elegans)
MET phosphorylates GAB1 (Xenopus tropicalis)
MET phosphorylates GAB1 (Sus scrofa)
MET phosphorylates GAB1 (Bos taurus)
MET phosphorylates GAB1 (Canis familiaris)
MET phosphorylates GAB1 (Rattus norvegicus)
MET phosphorylates GAB1 (Mus musculus)
MET phosphorylates GAB1 (Homo sapiens)
MET phosphorylates GAB1 (Gallus gallus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
Acidification of Tf:TfR1 containing endosome (Plasmodium falciparum)
Acidification of Tf:TfR1 containing endosome (Saccharomyces cerevisiae)
Acidification of Tf:TfR1 containing endosome (Schizosaccharomyces pombe)
Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)
Acidification of Tf:TfR1 containing endosome (Caenorhabditis elegans)
Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
Acidification of Tf:TfR1 containing endosome (Danio rerio)
Acidification of Tf:TfR1 containing endosome (Canis familiaris)
Acidification of Tf:TfR1 containing endosome (Gallus gallus)
Acidification of Tf:TfR1 containing endosome (Sus scrofa)
Acidification of Tf:TfR1 containing endosome (Bos taurus)
Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)
Acidification of Tf:TfR1 containing endosome (Mus musculus)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Drosophila melanogaster)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Gallus gallus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Xenopus tropicalis)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Sus scrofa)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Bos taurus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Rattus norvegicus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Mus musculus)
PTPS is phosphorylated by cGMP-dependant protein kinase II (Homo sapiens)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Drosophila melanogaster)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Gallus gallus)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Xenopus tropicalis)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Sus scrofa)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Bos taurus)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Canis familiaris)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Rattus norvegicus)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Mus musculus)
Sepiapterin reductase (SPR) is phosphorylated by Ca2+/calmodulin-dependent protein kinase II (Homo sapiens)
PRKCZ autophosphorylates downstream of estrogen stimulation (Saccharomyces cerevisiae)
PRKCZ autophosphorylates downstream of estrogen stimulation (Schizosaccharomyces pombe)
PRKCZ autophosphorylates downstream of estrogen stimulation (Dictyostelium discoideum)
PRKCZ autophosphorylates downstream of estrogen stimulation (Caenorhabditis elegans)
PRKCZ autophosphorylates downstream of estrogen stimulation (Gallus gallus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Sus scrofa)
PRKCZ autophosphorylates downstream of estrogen stimulation (Bos taurus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Canis familiaris)
PRKCZ autophosphorylates downstream of estrogen stimulation (Rattus norvegicus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Mus musculus)
PDK1 activates PKC zeta (Rattus norvegicus)
PDPK1 activates PRKCZ (Homo sapiens)
PRKCZ autophosphorylates downstream of estrogen stimulation (Homo sapiens)
PRKCZ autophosphorylates downstream of estrogen stimulation (Drosophila melanogaster)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Gallus gallus)
AKT1 phosphorylates eNOS (Sus scrofa)
AKT1 phosphorylates eNOS (Bos taurus)
AKT1 phosphorylates eNOS (Rattus norvegicus)
AKT1 phosphorylates eNOS (Mus musculus)
AKT1 phosphorylates eNOS (Homo sapiens)
AKT1 phosphorylates eNOS (Drosophila melanogaster)
ESR-associated SRC autophosphorylates (Gallus gallus)
ESR-associated SRC autophosphorylates (Danio rerio)
ESR-associated SRC autophosphorylates (Sus scrofa)
ESR-associated SRC autophosphorylates (Bos taurus)
ESR-associated SRC autophosphorylates (Canis familiaris)
ESR-associated SRC autophosphorylates (Rattus norvegicus)
ESR-associated SRC autophosphorylates (Mus musculus)
ESR-associated SRC autophosphorylates (Homo sapiens)
ESR-associated SRC autophosphorylates (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Caenorhabditis elegans)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Xenopus tropicalis)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Danio rerio)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Sus scrofa)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR1-associated FRS2. (Drosophila melanogaster)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR1- and PTPN11- associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR1-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Gallus gallus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Xenopus tropicalis)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Danio rerio)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Sus scrofa)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Bos taurus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Canis familiaris)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Mus musculus)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Homo sapiens)
Activated FGFR1:p-FRS phosphorylates PPTN11 (Drosophila melanogaster)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Drosophila melanogaster)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Bos taurus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Canis familiaris)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Rattus norvegicus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Mus musculus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y427-SHC1 (Homo sapiens)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Drosophila melanogaster)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Sus scrofa)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Bos taurus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Canis familiaris)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Rattus norvegicus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Mus musculus)
MAPK3,(MAPK1) phosphorylates GRB2-1:SOS1:p-Y-IRS1,p-Y-IRS2 (Homo sapiens)
Ntrk1,2,3 in Ade-Rib:Adora2a:Ntrk1,2,3 autophosphorylates (Rattus norvegicus)
NTRK1,2 in Ade-Rib:ADORA2A:NTRK1,2 autophosphorylates (Homo sapiens)
Ntrk1,2,3 in Adcyap1:Adcyap1r1:Ntrk1,2,3 autophosphorylates (Rattus norvegicus)
NTRK1,2 in ADCYAP1(2-742):ADCYAP1R1:NTRK1,2 autophosphorylates (Homo sapiens)
NRIF and TRAF6 may activate JNK (Mus musculus)
NRIF and TRAF6 may activate JNK (Homo sapiens)
JNK phosphorylates BIM, BAD and other targets (Bos taurus)
JNK phosphorylates BIM, BAD and other targets (Canis familiaris)
JNK phosphorylates BIM, BAD and other targets (Rattus norvegicus)
JNK phosphorylates BIM, BAD and other targets (Mus musculus)
Nrage activates Jnk1 (Rattus norvegicus)
NRAGE activates JNK (Homo sapiens)
JNK phosphorylates BIM, BAD and other targets (Homo sapiens)
JNK phosphorylates BIM, BAD and other targets (Sus scrofa)
GTP-bound RAC contributes to JNK activation (Dictyostelium discoideum)
GTP-bound RAC contributes to JNK activation (Caenorhabditis elegans)
GTP-bound RAC contributes to JNK activation (Drosophila melanogaster)
GTP-bound RAC contributes to JNK activation (Gallus gallus)
GTP-bound RAC contributes to JNK activation (Danio rerio)
GTP-bound RAC contributes to JNK activation (Bos taurus)
GTP-bound RAC contributes to JNK activation (Canis familiaris)
GTP-bound RAC contributes to JNK activation (Rattus norvegicus)
GTP-bound RAC contributes to JNK activation (Mus musculus)
GTP-bound RAC contributes to JNK activation (Homo sapiens)
GTP-bound RAC contributes to JNK activation (Sus scrofa)
Rap1-GTP phosphorylates Raf1 (Rattus norvegicus)
BRAF in Rap1-GTP complex:BRAF complex autophosphorylates (Homo sapiens)
ARMS is phosphorylated by active TrkA receptor (Gallus gallus)
ARMS is phosphorylated by active TrkA receptor (Xenopus tropicalis)
ARMS is phosphorylated by active TrkA receptor (Danio rerio)
ARMS is phosphorylated by active TrkA receptor (Bos taurus)
ARMS is phosphorylated by active TrkA receptor (Canis familiaris)
ARMS is phosphorylated by active TrkA receptor (Rattus norvegicus)
ARMS is phosphorylated by active TrkA receptor (Mus musculus)
ARMS is phosphorylated by active TrkA receptor (Homo sapiens)
ARMS is phosphorylated by active TrkA receptor (Sus scrofa)
SHC, complexed with TrkA, is tyrosine-phosphorylated (Homo sapiens)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Caenorhabditis elegans)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Drosophila melanogaster)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Gallus gallus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Danio rerio)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Bos taurus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Rattus norvegicus)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Mus musculus)
Binding and activation of MAP kinase (Rattus norvegicus)
SRC-1 autophosphorylates (Homo sapiens)
Binding and activation of MAP Kinase (Homo sapiens)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Homo sapiens)
p38 MAPK activation by VEGFR (Caenorhabditis elegans)
p38 MAPK activation by VEGFR (Drosophila melanogaster)
p38 MAPK activation by VEGFR (Gallus gallus)
p38 MAPK activation by VEGFR (Xenopus tropicalis)
p38 MAPK activation by VEGFR (Danio rerio)
p38 MAPK activation by VEGFR (Bos taurus)
p38 MAPK activation by VEGFR (Canis familiaris)
p38 MAPK activation by VEGFR (Rattus norvegicus)
p38 MAPK activation by VEGFR (Mus musculus)
p38 MAPK activation by VEGFR (Homo sapiens)
FYN phosphorylates PAK2 (Caenorhabditis elegans)
FYN phosphorylates PAK2 (Drosophila melanogaster)
FYN phosphorylates PAK2 (Gallus gallus)
FYN phosphorylates PAK2 (Xenopus tropicalis)
FYN phosphorylates PAK2 (Danio rerio)
FYN phosphorylates PAK2 (Bos taurus)
FYN phosphorylates PAK2 (Canis familiaris)
FYN phosphorylates PAK2 (Rattus norvegicus)
FYN phosphorylates PAK2 (Mus musculus)
FYN phosphorylates PAK2 (Homo sapiens)
PAK2 autophorylates (Caenorhabditis elegans)
PAK2 autophorylates (Drosophila melanogaster)
PAK2 autophorylates (Gallus gallus)
PAK2 autophorylates (Xenopus tropicalis)
PAK2 autophorylates (Danio rerio)
PAK2 autophorylates (Bos taurus)
PAK2 autophorylates (Canis familiaris)
PAK2 autophorylates (Rattus norvegicus)
PAK2 autophorylates (Mus musculus)
PAK2 autophorylates (Homo sapiens)
p-Y420-FYN is phosphorylated on S21 (Caenorhabditis elegans)
p-Y420-FYN is phosphorylated on S21 (Drosophila melanogaster)
p-Y420-FYN is phosphorylated on S21 (Xenopus tropicalis)
p-Y420-FYN is phosphorylated on S21 (Danio rerio)
p-Y420-FYN is phosphorylated on S21 (Bos taurus)
p-Y420-FYN is phosphorylated on S21 (Canis familiaris)
p-Y420-FYN is phosphorylated on S21 (Rattus norvegicus)
p-Y420-FYN is phosphorylated on S21 (Mus musculus)
p-Y420-FYN is phosphorylated on S21 (Homo sapiens)
FYN autophosphorylates (Caenorhabditis elegans)
FYN autophosphorylates (Drosophila melanogaster)
FYN autophosphorylates (Gallus gallus)
FYN autophosphorylates (Xenopus tropicalis)
FYN autophosphorylates (Danio rerio)
FYN autophosphorylates (Bos taurus)
FYN autophosphorylates (Canis familiaris)
FYN autophosphorylates (Rattus norvegicus)
FYN autophosphorylates (Mus musculus)
FYN autophosphorylates (Homo sapiens)
FYN autophosphorylates (Sus scrofa)
p-Y420-FYN is phosphorylated on S21 (Sus scrofa)
PAK2 autophorylates (Sus scrofa)
FYN phosphorylates PAK2 (Sus scrofa)
p38 MAPK activation by VEGFR (Sus scrofa)
p38 MAPK phosphorylates MAPKAPK2, MAPKAPK3 (Sus scrofa)
Phosphorylation and activation of VAV1 (Xenopus tropicalis)
Phosphorylation and activation of VAV1 (Sus scrofa)
Phosphorylation and activation of VAV1 (Bos taurus)
Phosphorylation and activation of VAV1 (Canis familiaris)
Phosphorylation and activation of VAV1 (Rattus norvegicus)
Phosphorylation and activation of VAV1 (Mus musculus)
Phosphorylation and activation of VAV1 (Homo sapiens)
Phosphorylation of STATs (Drosophila melanogaster)
Phosphorylation of STATs (Gallus gallus)
Phosphorylation of STATs (Xenopus tropicalis)
Phosphorylation of STATs (Sus scrofa)
Phosphorylation of STATs (Bos taurus)
Phosphorylation of STATs (Canis familiaris)
Phosphorylation of STATs (Rattus norvegicus)
Phosphorylation of STATs (Mus musculus)
Phosphorylation of STATs (Homo sapiens)
Phosphorylation of STATs (Danio rerio)
Synthesis of PIP3 from PIP2 by PI3K (Caenorhabditis elegans)
Synthesis of PIP3 from PIP2 by PI3K (Gallus gallus)
Synthesis of PIP3 from PIP2 by PI3K (Xenopus tropicalis)
Synthesis of PIP3 from PIP2 by PI3K (Sus scrofa)
Synthesis of PIP3 from PIP2 by PI3K (Bos taurus)
Synthesis of PIP3 from PIP2 by PI3K (Canis familiaris)
Synthesis of PIP3 from PIP2 by PI3K (Rattus norvegicus)
Synthesis of PIP3 from PIP2 by PI3K (Mus musculus)
Phosphorylation of GAB2 by SFKs (Gallus gallus)
Phosphorylation of GAB2 by SFKs (Xenopus tropicalis)
Phosphorylation of GAB2 by SFKs (Sus scrofa)
Phosphorylation of GAB2 by SFKs (Bos taurus)
Phosphorylation of GAB2 by SFKs (Canis familiaris)
Phosphorylation of GAB2 by SFKs (Rattus norvegicus)
Phosphorylation of GAB2 by SFKs (Mus musculus)
Phosphorylation of SHP2 by SFKs (Gallus gallus)
Phosphorylation of SHP2 by SFKs (Xenopus tropicalis)
Phosphorylation of SHP2 by SFKs (Danio rerio)
Phosphorylation of SHP2 by SFKs (Sus scrofa)
Phosphorylation of SHP2 by SFKs (Bos taurus)
Phosphorylation of SHP2 by SFKs (Canis familiaris)
Phosphorylation of SHP2 by SFKs (Rattus norvegicus)
Phosphorylation of SHP2 by SFKs (Mus musculus)
Phosphorylation of SHP2 by SFKs (Homo sapiens)
Phosphorylation of GAB2 by SFKs (Homo sapiens)
Synthesis of PIP3 from PIP2 by PI3K (Homo sapiens)
Synthesis of PIP3 from PIP2 by PI3K (Danio rerio)
Phosphorylation of JAK2 (Drosophila melanogaster)
Phosphorylation of JAK2 (Gallus gallus)
Phosphorylation of JAK2 (Xenopus tropicalis)
Phosphorylation of JAK2 (Sus scrofa)
Phosphorylation of JAK2 (Bos taurus)
Phosphorylation of JAK2 (Canis familiaris)
Phosphorylation of JAK2 (Rattus norvegicus)
Phosphorylation of JAK2 (Mus musculus)
Phosphorylation of JAK2 (Homo sapiens)
Phosphorylation of JAK2 (Danio rerio)
Phosphorylation of p-KIT on Y900 by Src kinases (Gallus gallus)
Phosphorylation of p-KIT on Y900 by Src kinases (Xenopus tropicalis)
Phosphorylation of p-KIT on Y900 by Src kinases (Sus scrofa)
Phosphorylation of p-KIT on Y900 by Src kinases (Bos taurus)
Phosphorylation of p-KIT on Y900 by Src kinases (Canis familiaris)
Phosphorylation of p-KIT on Y900 by Src kinases (Rattus norvegicus)
Phosphorylation of p-KIT on Y900 by Src kinases (Mus musculus)
Phosphorylation of p-KIT on Y900 by Src kinases (Homo sapiens)
Phosphorylation of p-KIT on Y900 by Src kinases (Danio rerio)
PKC alpha interacts with and phosphorylates KIT (Caenorhabditis elegans)
PKC alpha interacts with and phosphorylates KIT (Drosophila melanogaster)
PKC alpha interacts with and phosphorylates KIT (Gallus gallus)
PKC alpha interacts with and phosphorylates KIT (Sus scrofa)
PKC alpha interacts with and phosphorylates KIT (Canis familiaris)
PKC alpha interacts with and phosphorylates KIT (Rattus norvegicus)
PKC alpha interacts with and phosphorylates KIT (Mus musculus)
PKC alpha interacts with and phosphorylates KIT (Homo sapiens)
Phosphorylation of APS (Drosophila melanogaster)
Phosphorylation of APS (Gallus gallus)
Phosphorylation of APS (Xenopus tropicalis)
Phosphorylation of APS (Sus scrofa)
Phosphorylation of APS (Bos taurus)
Phosphorylation of APS (Canis familiaris)
Phosphorylation of APS (Rattus norvegicus)
Phosphorylation of APS (Mus musculus)
Phosphorylation of APS (Homo sapiens)
Phosphorylation of APS (Danio rerio)
Kif17 transports GluN1:GluN2B (Grin1:Grin2b) NMDA receptors to the plasma membrane (Mus musculus)
KIF17 transports GluN1:GluN2B (GRIN1:GRIN2B) NMDA receptors to the plasma membrane (Homo sapiens)
AMPK phosphorylates Mapt (Rattus norvegicus)
AMPK phosphorylates MAPT (Homo sapiens)
Camkk2 phosphorylates AMPK (Rattus norvegicus)
CAMKK2 phosphorylates AMPK (Homo sapiens)
Camk2 phosphorylates GluA1 (Gria1) (Rattus norvegicus)
CaMKII phosphorylates AMPA receptor (Homo sapiens)
Src phosphorylates GluN2 (Grin2) subunits of NMDARs (Rattus norvegicus)
SRC phosphorylates GluN2 (GRIN2) subunits of NMDARs (Homo sapiens)
Camk1 phosphorylates Arhgef7 (Rattus norvegicus)
CAMK1 phosphorylates ARHGEF7-1 (Homo sapiens)
CAMKK2 phosphorylates Camk1 (Homo sapiens)
CAMKK1 phosphorylates CAMK1 (Homo sapiens)
CaMKKs phosphorylate CAMK1 (Homo sapiens)
CaMKK autophosphorylates in the cytosol (Schizosaccharomyces pombe)
CaMKK autophosphorylates in the cytosol (Caenorhabditis elegans)
CaMKK autophosphorylates in the cytosol (Bos taurus)
CaMKK autophosphorylates in the cytosol (Canis familiaris)
CaMKK autophosphorylates in the cytosol (Rattus norvegicus)
CaMKK autophosphorylates in the cytosol (Mus musculus)
CaMKK autophosphorylates in the cytosol (Homo sapiens)
CaMKK autophosphorylates in the cytosol (Sus scrofa)
Endocytosis of Ca impermeable AMPA receptors (Drosophila melanogaster)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Drosophila melanogaster)
Trafficking of GluR2-containing AMPA receptors to synapse (Drosophila melanogaster)
Endocytosis of Ca impermeable AMPA receptors (Gallus gallus)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Gallus gallus)
Trafficking of GluR2-containing AMPA receptors to synapse (Gallus gallus)
Endocytosis of Ca impermeable AMPA receptors (Bos taurus)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Bos taurus)
Trafficking of GluR2-containing AMPA receptors to synapse (Bos taurus)
Endocytosis of Ca impermeable AMPA receptors (Canis familiaris)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Canis familiaris)
Trafficking of GluR2-containing AMPA receptors to synapse (Canis familiaris)
Endocytosis of Ca impermeable AMPA receptors (Rattus norvegicus)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Rattus norvegicus)
Trafficking of GluR2-containing AMPA receptors to synapse (Rattus norvegicus)
Trafficking of GluR2-containing AMPA receptors to synapse (Homo sapiens)
Trafficking of GluR2-containing AMPA receptors to synapse (Mus musculus)
Endocytosis of Ca impermeable AMPA receptors (Mus musculus)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Mus musculus)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Homo sapiens)
Endocytosis of Ca impermeable AMPA receptors (Sus scrofa)
Trafficking of GluR2-containing AMPA receptors to extrasynaptic sites (Sus scrofa)
Trafficking of GluR2-containing AMPA receptors to synapse (Sus scrofa)
Trafficking of GluR1-containing AMPA receptors (Bos taurus)
Trafficking of GluR1-containing AMPA receptors (Canis familiaris)
Trafficking of GluR1-containing AMPA receptors (Rattus norvegicus)
Trafficking of GluR1-containing AMPA receptors (Mus musculus)
Trafficking of GluR1-containing AMPA receptors (Homo sapiens)
Trafficking of GluR1-containing AMPA receptors (Sus scrofa)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Saccharomyces cerevisiae)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Schizosaccharomyces pombe)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Caenorhabditis elegans)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Drosophila melanogaster)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Gallus gallus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Xenopus tropicalis)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Danio rerio)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Bos taurus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Canis familiaris)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Rattus norvegicus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Mus musculus)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Homo sapiens)
glutamate + NH4+ + ATP => glutamine + ADP + orthophosphate [GLUL] (Sus scrofa)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR3-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
FGFR3- and PTPN11-associated PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Drosophila melanogaster)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Gallus gallus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Bos taurus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Rattus norvegicus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Mus musculus)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Homo sapiens)
Activated ERK1/2 threonine-phosphorylates FGFR3-associated FRS2. (Canis familiaris)
SPRY2 is phosphorylated by phosphorylated MNK1 (Drosophila melanogaster)
SPRY2 is phosphorylated by phosphorylated MNK1 (Xenopus tropicalis)
SPRY2 is phosphorylated by phosphorylated MNK1 (Sus scrofa)
SPRY2 is phosphorylated by phosphorylated MNK1 (Bos taurus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Rattus norvegicus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Mus musculus)
SPRY2 is phosphorylated by phosphorylated MNK1 (Homo sapiens)
SPRY2 is phosphorylated by phosphorylated MNK1 (Canis familiaris)
SRC phosphorylates SPRY2 on Y55 and Y227 (Drosophila melanogaster)
SRC phosphorylates SPRY2 on Y55 and Y227 (Danio rerio)
SRC phosphorylates SPRY2 on Y55 and Y227 (Sus scrofa)
SRC phosphorylates SPRY2 on Y55 and Y227 (Bos taurus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Rattus norvegicus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Mus musculus)
SRC phosphorylates SPRY2 on Y55 and Y227 (Homo sapiens)
SRC phosphorylates SPRY2 on Y55 and Y227 (Canis familiaris)
PECAM1 is phosphorylated (Gallus gallus)
PECAM1 is phosphorylated (Sus scrofa)
PECAM1 is phosphorylated (Bos taurus)
PECAM1 is phosphorylated (Rattus norvegicus)
PECAM1 is phosphorylated (Mus musculus)
PECAM1 is phosphorylated (Homo sapiens)
PECAM1 is phosphorylated (Canis familiaris)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Gallus gallus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Sus scrofa)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Bos taurus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Rattus norvegicus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Mus musculus)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Homo sapiens)
Phosphorylation of PECAM-1 by Fyn or Lyn or c-Src (Canis familiaris)
Phosphorylation and activation of VAV2/VAV3 by SYK (Gallus gallus)
Phosphorylation and activation of VAV2/VAV3 by SYK (Sus scrofa)
Phosphorylation and activation of VAV2/VAV3 by SYK (Canis familiaris)
Phosphorylation and activation of VAV2/VAV3 by SYK (Mus musculus)
Phosphorylation and activation of VAV2/VAV3 by SYK (Homo sapiens)
Phosphorylation and activation of VAV2/VAV3 by SYK (Rattus norvegicus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Drosophila melanogaster)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Gallus gallus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Xenopus tropicalis)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Sus scrofa)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Bos taurus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Canis familiaris)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Mus musculus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Homo sapiens)
Phosphorylation of BTK by p-SYK (Gallus gallus)
Phosphorylation of BTK by p-SYK (Sus scrofa)
Phosphorylation of BTK by p-SYK (Canis familiaris)
Phosphorylation of BTK by p-SYK (Mus musculus)
Phosphorylation of BTK by p-SYK (Homo sapiens)
Phosphorylation of BTK by p-SYK (Rattus norvegicus)
Phosphorylation of PLC-gamma by p-BTK/p-SYK (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
Phosphorylation of SLP-76 by p-SYK (Gallus gallus)
Phosphorylation of SLP-76 by p-SYK (Sus scrofa)
Phosphorylation of SLP-76 by p-SYK (Canis familiaris)
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
Phosphorylation of SLP-76 by p-SYK (Homo sapiens)
Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Dictyostelium discoideum)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Caenorhabditis elegans)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Gallus gallus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Danio rerio)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
Activated Akt1 phosphorylates AKT1S1 (PRAS40) (Mus musculus)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Dictyostelium discoideum)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Caenorhabditis elegans)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Gallus gallus)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Sus scrofa)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Bos taurus)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Canis familiaris)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Rattus norvegicus)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Homo sapiens)
Phosphorylation and inactivation of eEF2K by activated S6K1 (Mus musculus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Dictyostelium discoideum)
Phosphorylation of 4E-BP1 by activated mTORC1 (Drosophila melanogaster)
Phosphorylation of 4E-BP1 by activated mTORC1 (Gallus gallus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Danio rerio)
Phosphorylation of 4E-BP1 by activated mTORC1 (Sus scrofa)
Phosphorylation of 4E-BP1 by activated mTORC1 (Bos taurus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Canis familiaris)
Phosphorylation of 4E-BP1 by activated mTORC1 (Rattus norvegicus)
Phosphorylation of 4E-BP1 by activated mTORC1 (Homo sapiens)
Phosphorylation of 4E-BP1 by activated mTORC1 (Mus musculus)
Phosphorylation and activation of eIF4G by activated S6K1 (Saccharomyces cerevisiae)
Phosphorylation and activation of eIF4G by activated S6K1 (Schizosaccharomyces pombe)
Phosphorylation and activation of eIF4G by activated S6K1 (Dictyostelium discoideum)
Phosphorylation and activation of eIF4G by activated S6K1 (Caenorhabditis elegans)
Phosphorylation and activation of eIF4G by activated S6K1 (Drosophila melanogaster)
Phosphorylation and activation of eIF4G by activated S6K1 (Gallus gallus)
Phosphorylation and activation of eIF4G by activated S6K1 (Sus scrofa)
Phosphorylation and activation of eIF4G by activated S6K1 (Bos taurus)
Phosphorylation and activation of eIF4G by activated S6K1 (Canis familiaris)
Phosphorylation and activation of eIF4G by activated S6K1 (Rattus norvegicus)
Phosphorylation and activation of eIF4G by activated S6K1 (Homo sapiens)
Phosphorylation and activation of eIF4G by activated S6K1 (Mus musculus)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Saccharomyces cerevisiae)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Schizosaccharomyces pombe)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Dictyostelium discoideum)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Caenorhabditis elegans)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Drosophila melanogaster)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Gallus gallus)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Danio rerio)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Sus scrofa)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Bos taurus)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Canis familiaris)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Rattus norvegicus)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Homo sapiens)
Phosphorylation of Ribosomal protein S6 by activated S6K1 (Mus musculus)
Phosphorylation and activation of eIF4B by activated S6K1 (Saccharomyces cerevisiae)
Phosphorylation and activation of eIF4B by activated S6K1 (Schizosaccharomyces pombe)
Phosphorylation and activation of eIF4B by activated S6K1 (Gallus gallus)
Phosphorylation and activation of eIF4B by activated S6K1 (Sus scrofa)
Phosphorylation and activation of eIF4B by activated S6K1 (Bos taurus)
Phosphorylation and activation of eIF4B by activated S6K1 (Canis familiaris)
Phosphorylation and activation of eIF4B by activated S6K1 (Homo sapiens)
Phosphorylation and activation of eIF4B by activated S6K1 (Mus musculus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Dictyostelium discoideum)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Caenorhabditis elegans)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Drosophila melanogaster)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Gallus gallus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Danio rerio)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Sus scrofa)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Bos taurus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Canis familiaris)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Rattus norvegicus)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Homo sapiens)
mTORC1 phosphorylation of RPS6KB1 (S6K) (Mus musculus)
mTORC1 phosphorylates AKT1S1 (Dictyostelium discoideum)
mTORC1 phosphorylates AKT1S1 (Caenorhabditis elegans)
mTORC1 phosphorylates AKT1S1 (Drosophila melanogaster)
mTORC1 phosphorylates AKT1S1 (Gallus gallus)
mTORC1 phosphorylates AKT1S1 (Xenopus tropicalis)
mTORC1 phosphorylates AKT1S1 (Danio rerio)
mTORC1 phosphorylates AKT1S1 (Sus scrofa)
mTORC1 phosphorylates AKT1S1 (Bos taurus)
mTORC1 phosphorylates AKT1S1 (Canis familiaris)
mTORC1 phosphorylates AKT1S1 (Rattus norvegicus)
mTORC1 phosphorylates AKT1S1 (Homo sapiens)
mTORC1 phosphorylates AKT1S1 (Mus musculus)
Phosphorylation of complexed TSC2 by PKB (Schizosaccharomyces pombe)
Phosphorylation of complexed TSC2 by PKB (Drosophila melanogaster)
Phosphorylation of complexed TSC2 by PKB (Sus scrofa)
Phosphorylation of complexed TSC2 by PKB (Bos taurus)
Phosphorylation of complexed TSC2 by PKB (Rattus norvegicus)
Phosphorylation of complexed TSC2 by PKB (Homo sapiens)
Phosphorylation of complexed TSC2 by PKB (Mus musculus)
Phosphorylation of TSC2 by PKB (Schizosaccharomyces pombe)
Phosphorylation of TSC2 by PKB (Dictyostelium discoideum)
Phosphorylation of TSC2 by PKB (Drosophila melanogaster)
Phosphorylation of TSC2 by PKB (Sus scrofa)
Phosphorylation of TSC2 by PKB (Bos taurus)
Phosphorylation of TSC2 by PKB (Rattus norvegicus)
Phosphorylation of TSC2 by PKB (Homo sapiens)
Phosphorylation of TSC2 by PKB (Mus musculus)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Gallus gallus)
AMPK phosphorylates Raptor in the mTORC1 complex (Danio rerio)
AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)
Phosphorylation of PDE3B by AKT-1 (Mus musculus)
p-T309,S474-AKT2:PIP3 phosphorylates PDE3B (Homo sapiens)
PDPK1 phosphorylates AKT2 (Saccharomyces cerevisiae)
PDPK1 phosphorylates AKT2 (Schizosaccharomyces pombe)
PDPK1 phosphorylates AKT2 (Dictyostelium discoideum)
PDPK1 phosphorylates AKT2 (Caenorhabditis elegans)
PDPK1 phosphorylates AKT2 (Drosophila melanogaster)
PDPK1 phosphorylates AKT2 (Danio rerio)
PDPK1 phosphorylates AKT2 (Sus scrofa)
PDPK1 phosphorylates AKT2 (Bos taurus)
PDPK1 phosphorylates AKT2 (Rattus norvegicus)
PDPK1 phosphorylates AKT2 (Homo sapiens)
PDPK1 phosphorylates AKT2 (Mus musculus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Drosophila melanogaster)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Gallus gallus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Xenopus tropicalis)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Sus scrofa)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Bos taurus)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Canis familiaris)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Rattus norvegicus)
Gab2 in Active Flt3:Grb2:Gab2 is phosphorylated (Mus musculus)
GAB2 in Active FLT3:GRB2:GAB2 is phosphorylated (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Homo sapiens)
PI3K-containing complexes phosphorylate PIP2 to PIP3 (Mus musculus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Gallus gallus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Xenopus tropicalis)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Sus scrofa)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Bos taurus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Canis familiaris)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Rattus norvegicus)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Homo sapiens)
IGF1,2:p-Y1161,1165,1166-IGF1R phosphorylates IRS1,2,4 (Mus musculus)
IGF1R phosphorylates SHC1 (Gallus gallus)
IGF1R phosphorylates SHC1 (Xenopus tropicalis)
IGF1R phosphorylates SHC1 (Sus scrofa)
IGF1R phosphorylates SHC1 (Bos taurus)
IGF1R phosphorylates SHC1 (Canis familiaris)
IGF1R phosphorylates SHC1 (Rattus norvegicus)
IGF1R phosphorylates SHC1 (Homo sapiens)
IGF1R phosphorylates SHC1 (Mus musculus)
IGF1,2:IGF1R autophosphorylates (Gallus gallus)
IGF1,2:IGF1R autophosphorylates (Xenopus tropicalis)
IGF1,2:IGF1R autophosphorylates (Sus scrofa)
IGF1,2:IGF1R autophosphorylates (Bos taurus)
IGF1,2:IGF1R autophosphorylates (Canis familiaris)
IGF1,2:IGF1R autophosphorylates (Rattus norvegicus)
IGF1,2:IGF1R autophosphorylates (Homo sapiens)
IGF1,2:IGF1R autophosphorylates (Mus musculus)
PKC phosphorylates GRK2 (Caenorhabditis elegans)
PKC phosphorylates GRK2 (Drosophila melanogaster)
PKC phosphorylates GRK2 (Gallus gallus)
PKC phosphorylates GRK2 (Xenopus tropicalis)
PKC phosphorylates GRK2 (Sus scrofa)
PKC phosphorylates GRK2 (Bos taurus)
PKC phosphorylates GRK2 (Canis familiaris)
PKC phosphorylates GRK2 (Rattus norvegicus)
PKC phosphorylates GRK2 (Mus musculus)
PKC phosphorylates GRK2 (Homo sapiens)
Phosphorylation of CBL (EGFR:CBL) (Caenorhabditis elegans)
Phosphorylation of CBL (EGFR:CBL) (Drosophila melanogaster)
Phosphorylation of CBL (EGFR:CBL) (Gallus gallus)
Phosphorylation of CBL (EGFR:CBL) (Danio rerio)
Phosphorylation of CBL (EGFR:CBL) (Sus scrofa)
Phosphorylation of CBL (EGFR:CBL) (Bos taurus)
Phosphorylation of CBL (EGFR:CBL) (Canis familiaris)
Phosphorylation of CBL (EGFR:CBL) (Rattus norvegicus)
Phosphorylation of CBL (EGFR:CBL) (Mus musculus)
Phosphorylation of CBL (EGFR:CBL) (Homo sapiens)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Caenorhabditis elegans)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Drosophila melanogaster)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Gallus gallus)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Xenopus tropicalis)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Danio rerio)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Sus scrofa)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Bos taurus)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Canis familiaris)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Rattus norvegicus)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Mus musculus)
Phosphorylation of CBL (EGFR:GRB2:CBL) (Homo sapiens)
EGFR phosphorylates EPS15 (Caenorhabditis elegans)
EGFR phosphorylates EPS15 (Drosophila melanogaster)
EGFR phosphorylates EPS15 (Gallus gallus)
EGFR phosphorylates EPS15 (Sus scrofa)
EGFR phosphorylates EPS15 (Bos taurus)
EGFR phosphorylates EPS15 (Canis familiaris)
EGFR phosphorylates EPS15 (Rattus norvegicus)
EGFR phosphorylates EPS15 (Mus musculus)
EGFR phosphorylates EPS15 (Homo sapiens)
SEMA4D interacts with Plexin-B1:Met (Caenorhabditis elegans)
SEMA4D interacts with Plexin-B1:Met (Gallus gallus)
SEMA4D interacts with Plexin-B1:Met (Xenopus tropicalis)
SEMA4D interacts with Plexin-B1:Met (Sus scrofa)
SEMA4D interacts with Plexin-B1:Met (Bos taurus)
SEMA4D interacts with Plexin-B1:Met (Canis familiaris)
SEMA4D interacts with Plexin-B1:Met (Rattus norvegicus)
SEMA4D interacts with Plexin-B1:Met (Mus musculus)
SEMA4D interacts with Plexin-B1:Met (Homo sapiens)
Phosphorylation of Plexin-A (Mus musculus)
Phosphorylation of Plexin-A (Homo sapiens)
Tyrosine phosphorylation of CRMPs by Fes (Caenorhabditis elegans)
Tyrosine phosphorylation of CRMPs by Fes (Drosophila melanogaster)
Tyrosine phosphorylation of CRMPs by Fes (Gallus gallus)
Tyrosine phosphorylation of CRMPs by Fes (Xenopus tropicalis)
Tyrosine phosphorylation of CRMPs by Fes (Sus scrofa)
Tyrosine phosphorylation of CRMPs by Fes (Bos taurus)
Tyrosine phosphorylation of CRMPs by Fes (Canis familiaris)
Tyrosine phosphorylation of CRMPs by Fes (Rattus norvegicus)
Tyrosine phosphorylation of CRMPs by Fes (Mus musculus)
Tyrosine phosphorylation of CRMPs by Fes (Homo sapiens)
Phosphorylation of CRMPs by GSK3beta (Caenorhabditis elegans)
Phosphorylation of CRMPs by GSK3beta (Drosophila melanogaster)
Phosphorylation of CRMPs by GSK3beta (Gallus gallus)
Phosphorylation of CRMPs by GSK3beta (Sus scrofa)
Phosphorylation of CRMPs by GSK3beta (Bos taurus)
Phosphorylation of CRMPs by GSK3beta (Canis familiaris)
Phosphorylation of CRMPs by GSK3beta (Rattus norvegicus)
Phosphorylation of CRMPs by GSK3beta (Mus musculus)
Phosphorylation of CRMPs by Cdk5 (Caenorhabditis elegans)
Phosphorylation of CRMPs by Cdk5 (Drosophila melanogaster)
Phosphorylation of CRMPs by Cdk5 (Gallus gallus)
Phosphorylation of CRMPs by Cdk5 (Xenopus tropicalis)
Phosphorylation of CRMPs by Cdk5 (Danio rerio)
Phosphorylation of CRMPs by Cdk5 (Sus scrofa)
Phosphorylation of CRMPs by Cdk5 (Bos taurus)
Phosphorylation of CRMPs by Cdk5 (Canis familiaris)
Phosphorylation of CRMPs by Cdk5 (Rattus norvegicus)
Phosphorylation of CRMPs by Cdk5 (Mus musculus)
Recruitment and activation of Cdk5 (Homo sapiens)
Phosphorylation of CRMPs by Cdk5 (Homo sapiens)
Phosphorylation of CRMPs by GSK3beta (Homo sapiens)
Myosin phosphatase inactivation by ROCK2 (Bos taurus)
Myosin phosphatase inactivation by ROCK (Homo sapiens)
Ptk2 autophosphorylates at Y397 (Mus musculus)
PTK2 autophosphorylates at Y397 (Homo sapiens)
ROCK phosphorylates LIMK1,2 (Homo sapiens)
LIMK phosphorylates CFL1, inactivating it (Homo sapiens)
ROCK1 phosphorylates LIMK2 (rat) (Homo sapiens)
LIM kinase phosphorylation by ROCK (Homo sapiens)
Phosphorylation of LIMK-1 by PAK (Drosophila melanogaster)
Phosphorylation of LIMK-1 by PAK (Gallus gallus)
Phosphorylation of LIMK-1 by PAK (Xenopus tropicalis)
Phosphorylation of LIMK-1 by PAK (Danio rerio)
Phosphorylation of LIMK-1 by PAK (Sus scrofa)
Phosphorylation of LIMK-1 by PAK (Bos taurus)
Phosphorylation of LIMK-1 by PAK (Canis familiaris)
Phosphorylation of LIMK-1 by PAK (Rattus norvegicus)
Phosphorylation of LIMK-1 by PAK (Mus musculus)
Autophosphorylation of PAK (Caenorhabditis elegans)
Autophosphorylation of PAK (Drosophila melanogaster)
Autophosphorylation of PAK (Gallus gallus)
Autophosphorylation of PAK (Xenopus tropicalis)
Autophosphorylation of PAK (Danio rerio)
Autophosphorylation of PAK (Sus scrofa)
Autophosphorylation of PAK (Bos taurus)
Autophosphorylation of PAK (Canis familiaris)
Autophosphorylation of PAK (Rattus norvegicus)
Autophosphorylation of PAK (Mus musculus)
Autophosphorylation of PAK (Homo sapiens)
Phosphorylation of LIMK-1 by PAK (Homo sapiens)
Transphosphorylation of pLIMK1 (Dictyostelium discoideum)
Transphosphorylation of pLIMK1 (Drosophila melanogaster)
Transphosphorylation of pLIMK1 (Gallus gallus)
Transphosphorylation of pLIMK1 (Xenopus tropicalis)
Transphosphorylation of pLIMK1 (Danio rerio)
Transphosphorylation of pLIMK1 (Sus scrofa)
Transphosphorylation of pLIMK1 (Bos taurus)
Transphosphorylation of pLIMK1 (Canis familiaris)
Transphosphorylation of pLIMK1 (Rattus norvegicus)
Transphosphorylation of pLIMK1 (Mus musculus)
Transphosphorylation of pLIMK1 (Homo sapiens)
Phosphorylation of VAV (Gallus gallus)
Phosphorylation of VAV (Sus scrofa)
Phosphorylation of VAV (Bos taurus)
Phosphorylation of VAV (Canis familiaris)
Phosphorylation of VAV (Rattus norvegicus)
Phosphorylation of VAV (Mus musculus)
Phosphorylation of VAV (Homo sapiens)
Phosphorylation of SYK by Src kinases (Homo sapiens)
Limk1 phosphorylates Cfl1, inactivating it (Homo sapiens)
Phosphorylation of cofilin by LIMK-1 (Homo sapiens)
Src phosphorylate WASP,N-WASP (Caenorhabditis elegans)
Src phosphorylate WASP,N-WASP (Gallus gallus)
Src phosphorylate WASP,N-WASP (Bos taurus)
Src phosphorylate WASP,N-WASP (Canis familiaris)
Src phosphorylate WASP,N-WASP (Rattus norvegicus)
Src phosphorylate WASP,N-WASP (Mus musculus)
Src phosphorylate WASP,N-WASP (Homo sapiens)
p-ERK phosphorylates WAVEs and ABI (Dictyostelium discoideum)
p-ERK phosphorylates WAVEs and ABI (Caenorhabditis elegans)
p-ERK phosphorylates WAVEs and ABI (Drosophila melanogaster)
p-ERK phosphorylates WAVEs and ABI (Gallus gallus)
p-ERK phosphorylates WAVEs and ABI (Xenopus tropicalis)
p-ERK phosphorylates WAVEs and ABI (Sus scrofa)
p-ERK phosphorylates WAVEs and ABI (Bos taurus)
p-ERK phosphorylates WAVEs and ABI (Canis familiaris)
p-ERK phosphorylates WAVEs and ABI (Rattus norvegicus)
p-ERK phosphorylates WAVEs and ABI (Mus musculus)
ABL phosphorylates WAVEs (Caenorhabditis elegans)
ABL phosphorylates WAVEs (Drosophila melanogaster)
ABL phosphorylates WAVEs (Gallus gallus)
ABL phosphorylates WAVEs (Xenopus tropicalis)
ABL phosphorylates WAVEs (Sus scrofa)
ABL phosphorylates WAVEs (Bos taurus)
ABL phosphorylates WAVEs (Canis familiaris)
ABL phosphorylates WAVEs (Rattus norvegicus)
ABL phosphorylates WAVEs (Mus musculus)
p-6Y-SYK phosphorylates VAV1,2,3 (Homo sapiens)
Src kinases phosphorylate VAV (Gallus gallus)
Src kinases phosphorylate VAV (Sus scrofa)
Src kinases phosphorylate VAV (Bos taurus)
Src kinases phosphorylate VAV (Canis familiaris)
Src kinases phosphorylate VAV (Rattus norvegicus)
Src kinases phosphorylate VAV (Mus musculus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
AXL autophosphorylates on Y779 and Y821 (Caenorhabditis elegans)
AXL autophosphorylates on Y779 and Y821 (Gallus gallus)
AXL autophosphorylates on Y779 and Y821 (Sus scrofa)
AXL autophosphorylates on Y779 and Y821 (Bos taurus)
AXL autophosphorylates on Y779 and Y821 (Canis familiaris)
AXL autophosphorylates on Y779 and Y821 (Rattus norvegicus)
AXL autophosphorylates on Y779 and Y821 (Mus musculus)
Phosphorylation of SRC-1 (Caenorhabditis elegans)
Phosphorylation of SRC-1 (Gallus gallus)
Phosphorylation of SRC-1 (Danio rerio)
Phosphorylation of SRC-1 (Sus scrofa)
Phosphorylation of SRC-1 (Bos taurus)
Phosphorylation of SRC-1 (Canis familiaris)
Phosphorylation of SRC-1 (Rattus norvegicus)
Phosphorylation of SRC-1 (Mus musculus)
Phosphorylation of SRC-1 (Homo sapiens)
AXL autophosphorylates on Y779 and Y821 (Homo sapiens)
VEGFA dimer:p-6Y-VEGFR2 dimer:PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Src kinases phosphorylate VAV (Homo sapiens)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Gallus gallus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Sus scrofa)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Bos taurus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Canis familiaris)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Rattus norvegicus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Mus musculus)
PTK2 and SRC-1 phosphorylate PXN on Y31 and Y118 (Homo sapiens)
Fak/Src phosphorylate p130Cas (Mus musculus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Gallus gallus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Sus scrofa)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Bos taurus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Canis familiaris)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Rattus norvegicus)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Mus musculus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Gallus gallus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Sus scrofa)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Bos taurus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Canis familiaris)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Rattus norvegicus)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Mus musculus)
Phosphorylation of ephexin1 (Gallus gallus)
SFKs phosphorylate NGEF (Homo sapiens)
SRC-1 phosphorylates p-Y397-PTK2 (Gallus gallus)
SRC-1 phosphorylates p-Y397-PTK2 (Sus scrofa)
SRC-1 phosphorylates p-Y397-PTK2 (Bos taurus)
SRC-1 phosphorylates p-Y397-PTK2 (Canis familiaris)
SRC-1 phosphorylates p-Y397-PTK2 (Rattus norvegicus)
SRC-1 phosphorylates p-Y397-PTK2 (Mus musculus)
PTK2 autophosphorylates (Gallus gallus)
PTK2 autophosphorylates (Xenopus tropicalis)
PTK2 autophosphorylates (Sus scrofa)
PTK2 autophosphorylates (Bos taurus)
PTK2 autophosphorylates (Canis familiaris)
PTK2 autophosphorylates (Rattus norvegicus)
PTK2 autophosphorylates (Mus musculus)
SRC-1 phosphorylates SHB (Gallus gallus)
SRC-1 phosphorylates SHB (Sus scrofa)
SRC-1 phosphorylates SHB (Bos taurus)
SRC-1 phosphorylates SHB (Canis familiaris)
SRC-1 phosphorylates SHB (Rattus norvegicus)
SRC-1 phosphorylates SHB (Mus musculus)
SRC-1 phosphorylates SHB (Homo sapiens)
PTK2 autophosphorylates (Homo sapiens)
SRC-1 phosphorylates p-Y397-PTK2 (Homo sapiens)
Active ROCK1,ROCK2 phosphorylates p-5Y-PTK2 on S732 (Homo sapiens)
SRC-1 phosphorylates PTK2-beta (Gallus gallus)
SRC-1 phosphorylates PTK2-beta (Sus scrofa)
SRC-1 phosphorylates PTK2-beta (Bos taurus)
SRC-1 phosphorylates PTK2-beta (Canis familiaris)
SRC-1 phosphorylates PTK2-beta (Rattus norvegicus)
SRC-1 phosphorylates PTK2-beta (Mus musculus)
SRC-1 phosphorylates PTK2-beta (Homo sapiens)
p-Y402-PTK2B phosphorylates p-5Y,S732-PTK2 on Y407 (Homo sapiens)
PTK2/SRC-1 phosphorylates BCAR1 (Homo sapiens)
ABL phosphorylates WAVEs (Homo sapiens)
p-ERK phosphorylates WAVEs and ABI (Homo sapiens)
DAG stimulates protein kinase C-delta (Saccharomyces cerevisiae)
DAG stimulates protein kinase C-delta (Schizosaccharomyces pombe)
DAG stimulates protein kinase C-delta (Dictyostelium discoideum)
DAG stimulates protein kinase C-delta (Caenorhabditis elegans)
DAG stimulates protein kinase C-delta (Drosophila melanogaster)
DAG stimulates protein kinase C-delta (Gallus gallus)
DAG stimulates protein kinase C-delta (Xenopus tropicalis)
DAG stimulates protein kinase C-delta (Danio rerio)
DAG stimulates protein kinase C-delta (Sus scrofa)
DAG stimulates protein kinase C-delta (Bos taurus)
DAG stimulates protein kinase C-delta (Canis familiaris)
DAG stimulates protein kinase C-delta (Rattus norvegicus)
DAG stimulates protein kinase C-delta (Mus musculus)
DAG stimulates protein kinase C-delta (Homo sapiens)
PAK phosphorylates cortactin (Homo sapiens)
PAK1 phosphorylates FLNA (Dictyostelium discoideum)
PAK1 phosphorylates FLNA (Caenorhabditis elegans)
PAK1 phosphorylates FLNA (Drosophila melanogaster)
PAK1 phosphorylates FLNA (Xenopus tropicalis)
PAK1 phosphorylates FLNA (Sus scrofa)
PAK1 phosphorylates FLNA (Bos taurus)
PAK1 phosphorylates FLNA (Canis familiaris)
PAK1 phosphorylates FLNA (Rattus norvegicus)
PAK1 phosphorylates FLNA (Mus musculus)
PAK1 phosphorylates FLNA (Homo sapiens)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Saccharomyces cerevisiae)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Schizosaccharomyces pombe)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Dictyostelium discoideum)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Caenorhabditis elegans)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Drosophila melanogaster)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Gallus gallus)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Sus scrofa)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Bos taurus)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Rattus norvegicus)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Mus musculus)
PAK2 phosphorylates myosin regulatory light chain (MRLC) (Homo sapiens)
PAK1 or PAK2 phosphorylates MYLK (Gallus gallus)
PAK1 or PAK2 phosphorylates MYLK (Sus scrofa)
PAK1 or PAK2 phosphorylates MYLK (Bos taurus)
PAK1 or PAK2 phosphorylates MYLK (Canis familiaris)
PAK1 or PAK2 phosphorylates MYLK (Rattus norvegicus)
PAK1 or PAK2 phosphorylates MYLK (Mus musculus)
PAK1 or PAK2 phosphorylates MYLK (Homo sapiens)
PAK1 phosphorylates LIMK1 (Dictyostelium discoideum)
PAK1 phosphorylates LIMK1 (Drosophila melanogaster)
PAK1 phosphorylates LIMK1 (Gallus gallus)
PAK1 phosphorylates LIMK1 (Xenopus tropicalis)
PAK1 phosphorylates LIMK1 (Sus scrofa)
PAK1 phosphorylates LIMK1 (Bos taurus)
PAK1 phosphorylates LIMK1 (Canis familiaris)
PAK1 phosphorylates LIMK1 (Rattus norvegicus)
PAK1 phosphorylates LIMK1 (Mus musculus)
PAK1 phosphorylates LIMK1 (Homo sapiens)
Myosin regulatory light chain phosphorylation by Rock2 (Gallus gallus)
SEMA4D interacts with Plexin-B1:ErbB2 (Caenorhabditis elegans)
SEMA4D interacts with Plexin-B1:ErbB2 (Drosophila melanogaster)
SEMA4D interacts with Plexin-B1:ErbB2 (Gallus gallus)
SEMA4D interacts with Plexin-B1:ErbB2 (Sus scrofa)
SEMA4D interacts with Plexin-B1:ErbB2 (Bos taurus)
SEMA4D interacts with Plexin-B1:ErbB2 (Canis familiaris)
SEMA4D interacts with Plexin-B1:ErbB2 (Rattus norvegicus)
SEMA4D interacts with Plexin-B1:ErbB2 (Mus musculus)
SEMA4D interacts with Plexin-B1:ErbB2 (Homo sapiens)
Syk phosphorylates VAV1 (Homo sapiens)
p-Y348-SYK phosphorylates VAV family (Homo sapiens)
Myosin regulatory light chain phosphorylation by ROCK (Homo sapiens)
Activated Cit phosphorylates MRLCs of myosin II complex (Bos taurus)
Activated CIT phosphorylates MRLCs (Homo sapiens)
PAK1 phosphorylates myosin phosphatase (Caenorhabditis elegans)
PAK1 phosphorylates myosin phosphatase (Drosophila melanogaster)
PAK1 phosphorylates myosin phosphatase (Gallus gallus)
PAK1 phosphorylates myosin phosphatase (Xenopus tropicalis)
PAK1 phosphorylates myosin phosphatase (Sus scrofa)
PAK1 phosphorylates myosin phosphatase (Bos taurus)
PAK1 phosphorylates myosin phosphatase (Canis familiaris)
PAK1 phosphorylates myosin phosphatase (Rattus norvegicus)
PAK1 phosphorylates myosin phosphatase (Mus musculus)
Autophosphorylation of PAK1,2,3 (Saccharomyces cerevisiae)
Autophosphorylation of PAK1,2,3 (Schizosaccharomyces pombe)
Autophosphorylation of PAK1,2,3 (Dictyostelium discoideum)
Autophosphorylation of PAK1,2,3 (Caenorhabditis elegans)
Autophosphorylation of PAK1,2,3 (Drosophila melanogaster)
Autophosphorylation of PAK1,2,3 (Gallus gallus)
Autophosphorylation of PAK1,2,3 (Xenopus tropicalis)
Autophosphorylation of PAK1,2,3 (Danio rerio)
Autophosphorylation of PAK1,2,3 (Sus scrofa)
Autophosphorylation of PAK1,2,3 (Bos taurus)
Autophosphorylation of PAK1,2,3 (Canis familiaris)
Autophosphorylation of PAK1,2,3 (Rattus norvegicus)
Autophosphorylation of PAK1,2,3 (Mus musculus)
Autophosphorylation of PAK1,2,3 (Homo sapiens)
Autophosphorylation of PAK1 (Saccharomyces cerevisiae)
Autophosphorylation of PAK1 (Schizosaccharomyces pombe)
Autophosphorylation of PAK1 (Dictyostelium discoideum)
Autophosphorylation of PAK1 (Caenorhabditis elegans)
Autophosphorylation of PAK1 (Drosophila melanogaster)
Autophosphorylation of PAK1 (Gallus gallus)
Autophosphorylation of PAK1 (Xenopus tropicalis)
Autophosphorylation of PAK1 (Sus scrofa)
Autophosphorylation of PAK1 (Bos taurus)
Autophosphorylation of PAK1 (Canis familiaris)
Autophosphorylation of PAK1 (Rattus norvegicus)
Autophosphorylation of PAK1 (Mus musculus)
Autophosphorylation of PAK1 (Homo sapiens)
PAK1 phosphorylates myosin phosphatase (Homo sapiens)
Turkey MYLK phosphorylates MRLCs of the non-muscle myosin II complex (Meleagris gallopavo)
MYLK (MLCK) phosphorylates MRLCs of the non-muscle myosin II complex (Homo sapiens)
Phosphorylation of DCC by Fyn (Caenorhabditis elegans)
Phosphorylation of DCC by Fyn (Drosophila melanogaster)
Phosphorylation of DCC by Fyn (Gallus gallus)
Phosphorylation of DCC by Fyn (Xenopus tropicalis)
Phosphorylation of DCC by Fyn (Danio rerio)
Phosphorylation of DCC by Fyn (Bos taurus)
Phosphorylation of DCC by Fyn (Canis familiaris)
Phosphorylation of DCC by Fyn (Rattus norvegicus)
Phosphorylation of DCC by Fyn (Mus musculus)
Phosphorylation of FADK1 (Mus musculus)
Phosphorylation of FADK1 (Homo sapiens)
Phosphorylation of DCC by Fyn (Homo sapiens)
Activation of Vav1 (Gallus gallus)
Activation of Vav1 (Xenopus tropicalis)
Activation of Vav1 (Sus scrofa)
Activation of Vav1 (Bos taurus)
Activation of Vav1 (Canis familiaris)
Activation of Vav1 (Rattus norvegicus)
Activation of Vav1 (Mus musculus)
Activation of Vav1 (Homo sapiens)
PTK6 phosphorylates DOK1 (Caenorhabditis elegans)
PTK6 phosphorylates DOK1 (Danio rerio)
PTK6 phosphorylates DOK1 (Sus scrofa)
PTK6 phosphorylates DOK1 (Bos taurus)
PTK6 phosphorylates DOK1 (Rattus norvegicus)
PTK6 phosphorylates DOK1 (Mus musculus)
PTK6 phosphorylates DOK1 (Homo sapiens)
PTK6 phosphorylates ARAP1 (Caenorhabditis elegans)
PTK6 phosphorylates ARAP1 (Sus scrofa)
PTK6 phosphorylates ARAP1 (Bos taurus)
PTK6 phosphorylates ARAP1 (Rattus norvegicus)
PTK6 phosphorylates ARAP1 (Mus musculus)
PTK6 phosphorylates ARAP1 (Homo sapiens)
PTK6 phosphorylates CBL (Caenorhabditis elegans)
PTK6 phosphorylates CBL (Danio rerio)
PTK6 phosphorylates CBL (Sus scrofa)
PTK6 phosphorylates CBL (Bos taurus)
PTK6 phosphorylates CBL (Rattus norvegicus)
PTK6 phosphorylates CBL (Mus musculus)
PTK6 phosphorylates CBL (Homo sapiens)
PTK6 phosphorylates AKT1 (Caenorhabditis elegans)
PTK6 phosphorylates AKT1 (Danio rerio)
PTK6 phosphorylates AKT1 (Rattus norvegicus)
PTK6 phosphorylates AKT1 (Mus musculus)
PTK6 phosphorylates AKT1 (Homo sapiens)
PTK6 phosphorylates BCAR1 (Xenopus tropicalis)
PTK6 phosphorylates BCAR1 (Sus scrofa)
PTK6 phosphorylates BCAR1 (Bos taurus)
PTK6 phosphorylates BCAR1 (Rattus norvegicus)
PTK6 phosphorylates BCAR1 (Mus musculus)
PTK6 phosphorylates BCAR1 (Homo sapiens)
PTK6 phosphorylates ARHGAP35 (Caenorhabditis elegans)
PTK6 phosphorylates ARHGAP35 (Xenopus tropicalis)
PTK6 phosphorylates ARHGAP35 (Danio rerio)
PTK6 phosphorylates ARHGAP35 (Sus scrofa)
PTK6 phosphorylates ARHGAP35 (Bos taurus)
PTK6 phosphorylates ARHGAP35 (Rattus norvegicus)
PTK6 phosphorylates ARHGAP35 (Mus musculus)
PTK6 phosphorylates ARHGAP35 (Homo sapiens)
SRMS phosphorylates PTK6 (Caenorhabditis elegans)
SRMS phosphorylates PTK6 (Sus scrofa)
SRMS phosphorylates PTK6 (Bos taurus)
SRMS phosphorylates PTK6 (Rattus norvegicus)
SRMS phosphorylates PTK6 (Mus musculus)
SRMS phosphorylates PTK6 (Homo sapiens)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Gallus gallus)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Xenopus tropicalis)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Sus scrofa)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Bos taurus)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Rattus norvegicus)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Mus musculus)
LINC01139 promotes phosphorylation of HIF1A by LRRK2 (Homo sapiens)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Gallus gallus)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Xenopus tropicalis)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Sus scrofa)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Bos taurus)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Rattus norvegicus)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Mus musculus)
LINC01139 facilitates PTK6 autophosphorylation (Gallus gallus)
LINC01139 facilitates PTK6 autophosphorylation (Xenopus tropicalis)
LINC01139 facilitates PTK6 autophosphorylation (Sus scrofa)
LINC01139 facilitates PTK6 autophosphorylation (Bos taurus)
LINC01139 facilitates PTK6 autophosphorylation (Rattus norvegicus)
LINC01139 facilitates PTK6 autophosphorylation (Mus musculus)
LINC01139 facilitates PTK6 autophosphorylation (Homo sapiens)
LINC01139 promotes phosphorylation of HIF1A by PTK6 (Homo sapiens)
EGFR phosphorylates GPNMB (Gallus gallus)
EGFR phosphorylates GPNMB (Xenopus tropicalis)
EGFR phosphorylates GPNMB (Sus scrofa)
EGFR phosphorylates GPNMB (Bos taurus)
EGFR phosphorylates GPNMB (Rattus norvegicus)
EGFR phosphorylates GPNMB (Mus musculus)
EGFR phosphorylates GPNMB (Homo sapiens)
MET phosphorylates STAT3 (Caenorhabditis elegans)
MET phosphorylates STAT3 (Gallus gallus)
MET phosphorylates STAT3 (Xenopus tropicalis)
MET phosphorylates STAT3 (Sus scrofa)
MET phosphorylates STAT3 (Bos taurus)
MET phosphorylates STAT3 (Canis familiaris)
MET phosphorylates STAT3 (Rattus norvegicus)
MET phosphorylates STAT3 (Mus musculus)
MET phosphorylates STAT3 (Homo sapiens)
PTK6 phosphorylates STAT3 (Sus scrofa)
PTK6 phosphorylates STAT3 (Bos taurus)
PTK6 phosphorylates STAT3 (Rattus norvegicus)
PTK6 phosphorylates STAT3 (Mus musculus)
PTK6 phosphorylates STAT3 (Homo sapiens)
Jak2 Phosphorylates Stat3 in Response to Leptin (Mus musculus)
Jak2 Phosphorylates Lepr (Mus musculus)
Jak2 Autophosphorylates in Response to Leptin (Mus musculus)
JAK2 Autophosphorylates in Response to Leptin (Homo sapiens)
JAK2 Phosphorylates LEPR (Homo sapiens)
JAK2 Phosphoryates STAT3 in Response to Leptin (Homo sapiens)
PTK6 phosphorylates STAP2 (Danio rerio)
PTK6 phosphorylates STAP2 (Sus scrofa)
PTK6 phosphorylates STAP2 (Bos taurus)
PTK6 phosphorylates STAP2 (Rattus norvegicus)
PTK6 phosphorylates STAP2 (Mus musculus)
PTK6 phosphorylates STAP2 (Homo sapiens)
Phosphorylation of APC component of the destruction complex (Caenorhabditis elegans)
Phosphorylation of APC component of the destruction complex (Drosophila melanogaster)
Phosphorylation of APC component of the destruction complex (Gallus gallus)
Phosphorylation of APC component of the destruction complex (Sus scrofa)
Phosphorylation of APC component of the destruction complex (Bos taurus)
Phosphorylation of APC component of the destruction complex (Canis familiaris)
Phosphorylation of APC component of the destruction complex (Rattus norvegicus)
Phosphorylation of APC component of the destruction complex (Mus musculus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Caenorhabditis elegans)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Gallus gallus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Sus scrofa)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Bos taurus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Canis familiaris)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Rattus norvegicus)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Mus musculus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Caenorhabditis elegans)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Drosophila melanogaster)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Gallus gallus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Sus scrofa)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Bos taurus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Canis familiaris)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Rattus norvegicus)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Mus musculus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Caenorhabditis elegans)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Drosophila melanogaster)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Gallus gallus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Sus scrofa)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Bos taurus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Canis familiaris)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Rattus norvegicus)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Mus musculus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Caenorhabditis elegans)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Drosophila melanogaster)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Gallus gallus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Sus scrofa)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Bos taurus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Canis familiaris)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Rattus norvegicus)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Mus musculus)
AXIN is phosphorylated in the destruction complex (Caenorhabditis elegans)
AXIN is phosphorylated in the destruction complex (Drosophila melanogaster)
AXIN is phosphorylated in the destruction complex (Gallus gallus)
AXIN is phosphorylated in the destruction complex (Sus scrofa)
AXIN is phosphorylated in the destruction complex (Bos taurus)
AXIN is phosphorylated in the destruction complex (Canis familiaris)
AXIN is phosphorylated in the destruction complex (Rattus norvegicus)
AXIN is phosphorylated in the destruction complex (Mus musculus)
AXIN is phosphorylated in the destruction complex (Homo sapiens)
Phosphorylation of beta-catenin at Ser45 by CK1 alpha (Homo sapiens)
Phosphorylation of phospho-(Ser45 ) at Thr 41 by GSK-3 (Homo sapiens)
Phosphorylation of phospho- (Ser45, Thr41) beta-catenin at Ser37 by GSK-3 (Homo sapiens)
Phosphorylation of phospho-(Ser45,Thr41,Ser37) at Ser33 by GSK-3 (Homo sapiens)
Phosphorylation of APC component of the destruction complex (Homo sapiens)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Caenorhabditis elegans)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Drosophila melanogaster)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Gallus gallus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Sus scrofa)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Bos taurus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Canis familiaris)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Rattus norvegicus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Mus musculus)
DVL-associated PIP5K1B phosphorylates PI4P to PI(4,5)P2 (Homo sapiens)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Caenorhabditis elegans)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Drosophila melanogaster)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Gallus gallus)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Xenopus tropicalis)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Danio rerio)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Sus scrofa)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Bos taurus)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Rattus norvegicus)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Mus musculus)
WNT signaling stimulates CSNK1-dependent phosphorylation of DVL (Homo sapiens)
CSNK2-mediated phosphorylation of DVL (Caenorhabditis elegans)
CSNK2-mediated phosphorylation of DVL (Drosophila melanogaster)
CSNK2-mediated phosphorylation of DVL (Sus scrofa)
CSNK2-mediated phosphorylation of DVL (Bos taurus)
CSNK2-mediated phosphorylation of DVL (Canis familiaris)
CSNK2-mediated phosphorylation of DVL (Rattus norvegicus)
CSNK2-mediated phosphorylation of DVL (Mus musculus)
CSNK2-mediated phosphorylation of DVL (Homo sapiens)
frog CK1gamma phosphorylates LRP5/6 (Homo sapiens)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Caenorhabditis elegans)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Drosophila melanogaster)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Gallus gallus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Danio rerio)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Sus scrofa)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Bos taurus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Canis familiaris)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Rattus norvegicus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Mus musculus)
Phosphorylation of LRP5/6 cytoplasmic domain by membrane-associated GSK3beta (Homo sapiens)
Phosphorylation of LRP5/6 cytoplasmic domain by CSNKI (Homo sapiens)
Vangl2 is phosphorylated in response to Wnt5a (Mus musculus)
VANGL2 is phosphorylated in response to WNT5A (Homo sapiens)
DVL2 is phosphorylated by PKC (Caenorhabditis elegans)
DVL2 is phosphorylated by PKC (Xenopus tropicalis)
DVL2 is phosphorylated by PKC (Sus scrofa)
DVL2 is phosphorylated by PKC (Bos taurus)
DVL2 is phosphorylated by PKC (Canis familiaris)
DVL2 is phosphorylated by PKC (Rattus norvegicus)
DVL2 is phosphorylated by PKC (Mus musculus)
DVL2 is phosphorylated by PKC (Homo sapiens)
Activation of NLK (Drosophila melanogaster)
Activation of NLK (Gallus gallus)
Activation of NLK (Xenopus tropicalis)
Activation of NLK (Sus scrofa)
Activation of NLK (Bos taurus)
Activation of NLK (Canis familiaris)
Activation of NLK (Rattus norvegicus)
Activation of NLK (Mus musculus)
Activation of MAP3K7 in response to WNT (Homo sapiens)
Activation of NLK (Homo sapiens)
Dissociation of CaM and CAMK2 autophosphorylation (Plasmodium falciparum)
Dissociation of CaM and CAMK2 autophosphorylation (Caenorhabditis elegans)
Dissociation of CaM and CAMK2 autophosphorylation (Drosophila melanogaster)
Dissociation of CaM and CAMK2 autophosphorylation (Gallus gallus)
Dissociation of CaM and CAMK2 autophosphorylation (Sus scrofa)
Dissociation of CaM and CAMK2 autophosphorylation (Bos taurus)
Dissociation of CaM and CAMK2 autophosphorylation (Canis familiaris)
Dissociation of CaM and CAMK2 autophosphorylation (Rattus norvegicus)
Dissociation of CaM and CAMK2 autophosphorylation (Mus musculus)
Autophosphorylation and activation of CAMK2 (Plasmodium falciparum)
Autophosphorylation and activation of CAMK2 (Caenorhabditis elegans)
Autophosphorylation and activation of CAMK2 (Drosophila melanogaster)
Autophosphorylation and activation of CAMK2 (Gallus gallus)
Autophosphorylation and activation of CAMK2 (Sus scrofa)
Autophosphorylation and activation of CAMK2 (Bos taurus)
Autophosphorylation and activation of CAMK2 (Canis familiaris)
Autophosphorylation and activation of CAMK2 (Rattus norvegicus)
Autophosphorylation and activation of CAMK2 (Mus musculus)
Autophosphorylation and activation of CAMK2 (Homo sapiens)
Dissociation of CaM and CAMK2 autophosphorylation (Homo sapiens)
AURKB phosphorylates DIAPH2-2 at kinetochores (Gallus gallus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Sus scrofa)
AURKB phosphorylates DIAPH2-2 at kinetochores (Bos taurus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Canis familiaris)
AURKB phosphorylates DIAPH2-2 at kinetochores (Rattus norvegicus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Mus musculus)
AURKB phosphorylates DIAPH2-2 at kinetochores (Homo sapiens)
Rat Dvl is phosophorylated upon Wnt binding (Mus musculus)
WNT-dependent phosphorylation of DVL (Homo sapiens)
Phosphorylation of USP8 by P-AKT (Schizosaccharomyces pombe)
Phosphorylation of USP8 by P-AKT (Dictyostelium discoideum)
Phosphorylation of USP8 by P-AKT (Drosophila melanogaster)
Phosphorylation of USP8 by P-AKT (Gallus gallus)
Phosphorylation of USP8 by P-AKT (Rattus norvegicus)
Phosphorylation of USP8 by P-AKT (Mus musculus)
Phosphorylation of USP8 by P-AKT (Homo sapiens)
Plcg1 phosphorylation by P-ERBB2:P-EGFR (Homo sapiens)
PLCG1 phosphorylation by p-EGFR:p-ERBB2 (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Caenorhabditis elegans)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Gallus gallus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Xenopus tropicalis)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Sus scrofa)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Bos taurus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Canis familiaris)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Mus musculus)
PIP2 to PIP3 conversion by PI3K bound to GRB2:GAB1 in complex with phosphorylated heterodimer of ERBB2 and EGFR (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Caenorhabditis elegans)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Gallus gallus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Danio rerio)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Sus scrofa)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Bos taurus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Canis familiaris)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Mus musculus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB3 (Homo sapiens)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Caenorhabditis elegans)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Drosophila melanogaster)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Gallus gallus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Xenopus tropicalis)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Danio rerio)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Sus scrofa)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Bos taurus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Canis familiaris)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Rattus norvegicus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Mus musculus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Homo sapiens)
Activated PKC phosphorylates SHC1 (Drosophila melanogaster)
Activated PKC phosphorylates SHC1 (Gallus gallus)
Activated PKC phosphorylates SHC1 (Sus scrofa)
Activated PKC phosphorylates SHC1 (Canis familiaris)
Activated PKC phosphorylates SHC1 (Rattus norvegicus)
Activated PKC phosphorylates SHC1 (Mus musculus)
Activated PKC phosphorylates SHC1 (Homo sapiens)
Activated MAPK phosphorylates RAF1 (Plasmodium falciparum)
Activated MAPK phosphorylates RAF1 (Caenorhabditis elegans)
Activated MAPK phosphorylates RAF1 (Drosophila melanogaster)
Activated MAPK phosphorylates RAF1 (Gallus gallus)
Activated MAPK phosphorylates RAF1 (Xenopus tropicalis)
Activated MAPK phosphorylates RAF1 (Canis familiaris)
Activated MAPK phosphorylates RAF1 (Rattus norvegicus)
Activated MAPK phosphorylates RAF1 (Mus musculus)
Activated MAPK phosphorylates RAF1 (Homo sapiens)
Activated MAPKs phosphorylate BRAF (Plasmodium falciparum)
Activated MAPKs phosphorylate BRAF (Caenorhabditis elegans)
Activated MAPKs phosphorylate BRAF (Drosophila melanogaster)
Activated MAPKs phosphorylate BRAF (Gallus gallus)
Activated MAPKs phosphorylate BRAF (Sus scrofa)
Activated MAPKs phosphorylate BRAF (Bos taurus)
Activated MAPKs phosphorylate BRAF (Canis familiaris)
Activated MAPKs phosphorylate BRAF (Rattus norvegicus)
Activated MAPKs phosphorylate BRAF (Mus musculus)
Activated MAPKs phosphorylate BRAF (Homo sapiens)
Activated MAPKs phosphorylate MAP2K1 (Saccharomyces cerevisiae)
Activated MAPKs phosphorylate MAP2K1 (Schizosaccharomyces pombe)
Activated MAPKs phosphorylate MAP2K1 (Dictyostelium discoideum)
Activated MAPKs phosphorylate MAP2K1 (Caenorhabditis elegans)
Activated MAPKs phosphorylate MAP2K1 (Drosophila melanogaster)
Activated MAPKs phosphorylate MAP2K1 (Danio rerio)
Activated MAPKs phosphorylate MAP2K1 (Bos taurus)
Activated MAPKs phosphorylate MAP2K1 (Rattus norvegicus)
Activated MAPKs phosphorylate MAP2K1 (Mus musculus)
Activated MAPKs phosphorylate MAP2K1 (Homo sapiens)
MAPK12 phosphorylates PTPN3 (Caenorhabditis elegans)
MAPK12 phosphorylates PTPN3 (Drosophila melanogaster)
MAPK12 phosphorylates PTPN3 (Gallus gallus)
MAPK12 phosphorylates PTPN3 (Xenopus tropicalis)
MAPK12 phosphorylates PTPN3 (Sus scrofa)
MAPK12 phosphorylates PTPN3 (Bos taurus)
MAPK12 phosphorylates PTPN3 (Canis familiaris)
MAPK12 phosphorylates PTPN3 (Rattus norvegicus)
MAPK12 phosphorylates PTPN3 (Mus musculus)
MAPK12 phosphorylates PTPN3 (Homo sapiens)
KRAS4B is phosphorylated on serine 181 (Caenorhabditis elegans)
KRAS4B is phosphorylated on serine 181 (Drosophila melanogaster)
KRAS4B is phosphorylated on serine 181 (Gallus gallus)
KRAS4B is phosphorylated on serine 181 (Sus scrofa)
KRAS4B is phosphorylated on serine 181 (Canis familiaris)
KRAS4B is phosphorylated on serine 181 (Rattus norvegicus)
KRAS4B is phosphorylated on serine 181 (Mus musculus)
KRAS4B is phosphorylated on serine 181 (Homo sapiens)
KRAS4B is phosphorylated on serine 181 (Bos taurus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Saccharomyces cerevisiae)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Schizosaccharomyces pombe)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Dictyostelium discoideum)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Caenorhabditis elegans)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Drosophila melanogaster)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Gallus gallus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Danio rerio)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Sus scrofa)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Canis familiaris)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Rattus norvegicus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Mus musculus)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Homo sapiens)
MAP2Ks phosphorylate MAPK at the Golgi membrane (Bos taurus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Dictyostelium discoideum)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Caenorhabditis elegans)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Drosophila melanogaster)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Danio rerio)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Sus scrofa)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Canis familiaris)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Rattus norvegicus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Mus musculus)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Homo sapiens)
MAP2Ks and MAPKs are phosphorylated at the endosome membrane (Bos taurus)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:TIRAP:activated TLR complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 upon TLR7/8 or 9 activation (Mus musculus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Drosophila melanogaster)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Sus scrofa)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Bos taurus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Canis familiaris)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Rattus norvegicus)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Homo sapiens)
IRAK1 phosphorylates Pellino upon TLR7/8 or 9 activation (Mus musculus)
MAPK8 phosphorylation (Saccharomyces cerevisiae)
MAPK8 phosphorylation (Schizosaccharomyces pombe)
MAPK8 phosphorylation (Dictyostelium discoideum)
MAPK8 phosphorylation (Caenorhabditis elegans)
MAPK8 phosphorylation (Drosophila melanogaster)
MAPK8 phosphorylation (Gallus gallus)
MAPK8 phosphorylation (Danio rerio)
MAPK8 phosphorylation (Sus scrofa)
MAPK8 phosphorylation (Bos taurus)
MAPK8 phosphorylation (Canis familiaris)
MAPK8 phosphorylation (Rattus norvegicus)
MAPK8 phosphorylation (Homo sapiens)
MAPK8 phosphorylation (Mus musculus)
STAT3 phosphorylation (Dictyostelium discoideum)
STAT3 phosphorylation (Caenorhabditis elegans)
STAT3 phosphorylation (Drosophila melanogaster)
STAT3 phosphorylation (Gallus gallus)
STAT3 phosphorylation (Xenopus tropicalis)
STAT3 phosphorylation (Sus scrofa)
STAT3 phosphorylation (Bos taurus)
STAT3 phosphorylation (Canis familiaris)
STAT3 phosphorylation (Rattus norvegicus)
STAT3 phosphorylation (Mus musculus)
STAT3 phosphorylation (Homo sapiens)
TBK1 phosphorylation (Drosophila melanogaster)
TBK1 phosphorylation (Gallus gallus)
TBK1 phosphorylation (Xenopus tropicalis)
TBK1 phosphorylation (Danio rerio)
TBK1 phosphorylation (Sus scrofa)
TBK1 phosphorylation (Bos taurus)
TBK1 phosphorylation (Canis familiaris)
TBK1 phosphorylation (Rattus norvegicus)
TBK1 phosphorylation (Mus musculus)
TBK1 phosphorylation (Homo sapiens)
IRAK4 is activated by autophosphorylation (Gallus gallus)
IRAK4 is activated by autophosphorylation (Xenopus tropicalis)
IRAK4 is activated by autophosphorylation (Sus scrofa)
IRAK4 is activated by autophosphorylation (Bos taurus)
IRAK4 is activated by autophosphorylation (Rattus norvegicus)
IRAK4 is activated by autophosphorylation (Mus musculus)
IRAK4 is activated by autophosphorylation (Homo sapiens)
IRAK4 is activated by autophosphorylation (Canis familiaris)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Caenorhabditis elegans)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Drosophila melanogaster)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Sus scrofa)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Bos taurus)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Rattus norvegicus)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Mus musculus)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Homo sapiens)
hp-IRAK1, hp-IRAK4 4 phosphorylate Pellino-1 and 2. (Canis familiaris)
IRAK4 phosphorylates IRAK1 (Sus scrofa)
IRAK4 phosphorylates IRAK1 (Bos taurus)
IRAK4 phosphorylates IRAK1 (Rattus norvegicus)
IRAK4 phosphorylates IRAK1 (Mus musculus)
IRAK4 phosphorylates IRAK1 (Homo sapiens)
IRAK4 phosphorylates IRAK1 (Canis familiaris)
IKBA is phosphorylated by Phospho IKKB kinase (Drosophila melanogaster)
IKBA is phosphorylated by Phospho IKKB kinase (Gallus gallus)
IKBA is phosphorylated by Phospho IKKB kinase (Sus scrofa)
IKBA is phosphorylated by Phospho IKKB kinase (Bos taurus)
IKBA is phosphorylated by Phospho IKKB kinase (Rattus norvegicus)
IKBA is phosphorylated by Phospho IKKB kinase (Mus musculus)
IKBA is phosphorylated by Phospho IKKB kinase (Homo sapiens)
IKBA is phosphorylated by Phospho IKKB kinase (Canis familiaris)
IRAK4-activated IRAK1 autophosphorylates (Sus scrofa)
IRAK4-activated IRAK1 autophosphorylates (Bos taurus)
IRAK4-activated IRAK1 autophosphorylates (Rattus norvegicus)
IRAK4-activated IRAK1 autophosphorylates (Mus musculus)
IRAK4-activated IRAK1 autophosphorylates (Homo sapiens)
IRAK4-activated IRAK1 autophosphorylates (Canis familiaris)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Drosophila melanogaster)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Sus scrofa)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Bos taurus)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Canis familiaris)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Mus musculus)
p-S177,S181-IKKB:IKKA:pUb-NEMO phosphorylates IkB-alpha:NF-kB (Homo sapiens)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Sus scrofa)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Bos taurus)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Canis familiaris)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Rattus norvegicus)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Mus musculus)
K63polyUb-TAK1 autophosphorylates (Gallus gallus)
K63polyUb-TAK1 autophosphorylates (Sus scrofa)
K63polyUb-TAK1 autophosphorylates (Bos taurus)
K63polyUb-TAK1 autophosphorylates (Canis familiaris)
K63polyUb-TAK1 autophosphorylates (Rattus norvegicus)
K63polyUb-TAK1 autophosphorylates (Mus musculus)
PKC-delta phosphorylates CARD9 (Gallus gallus)
PKC-delta phosphorylates CARD9 (Xenopus tropicalis)
PKC-delta phosphorylates CARD9 (Sus scrofa)
PKC-delta phosphorylates CARD9 (Bos taurus)
PKC-delta phosphorylates CARD9 (Canis familiaris)
PKC-delta phosphorylates CARD9 (Rattus norvegicus)
PKC-delta phosphorylates CARD9 (Mus musculus)
1,3-beta-D-glucan:p-15Y-Clec7a:Syk phosphorylates Plcg2 (Mus musculus)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Sus scrofa)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Bos taurus)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Canis familiaris)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Rattus norvegicus)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Mus musculus)
SRC kinase phosphorylates CLEC7A:1,3-beta-D-glucan (Homo sapiens)
1,3-beta-D-glucan:p-Y15-CLEC7A:SYK phosphorylates PLCG (Homo sapiens)
PKC-delta phosphorylates CARD9 (Homo sapiens)
K63polyUb-TAK1 autophosphorylates (Homo sapiens)
K63polyUb-p-3T,1S-TAK1 phosphorylates IKK-beta (Homo sapiens)
Phosphorylation of IKK-beta by TAK1 (Sus scrofa)
Phosphorylation of IKK-beta by TAK1 (Bos taurus)
Phosphorylation of IKK-beta by TAK1 (Canis familiaris)
Phosphorylation of IKK-beta by TAK1 (Rattus norvegicus)
Phosphorylation of IKK-beta by TAK1 (Mus musculus)
Activation of TAK1 complex bound to pUb-TRAF6 (Gallus gallus)
Activation of TAK1 complex bound to pUb-TRAF6 (Sus scrofa)
Activation of TAK1 complex bound to pUb-TRAF6 (Bos taurus)
Activation of TAK1 complex bound to pUb-TRAF6 (Canis familiaris)
Activation of TAK1 complex bound to pUb-TRAF6 (Rattus norvegicus)
Activation of TAK1 complex bound to pUb-TRAF6 (Mus musculus)
Phosphorylation of CARMA1 by PKC-theta (Sus scrofa)
Phosphorylation of CARMA1 by PKC-theta (Bos taurus)
Phosphorylation of CARMA1 by PKC-theta (Canis familiaris)
Phosphorylation of CARMA1 by PKC-theta (Rattus norvegicus)
Phosphorylation of CARMA1 by PKC-theta (Mus musculus)
Autophosphorylation of PKC-theta (Saccharomyces cerevisiae)
Autophosphorylation of PKC-theta (Schizosaccharomyces pombe)
Autophosphorylation of PKC-theta (Dictyostelium discoideum)
Autophosphorylation of PKC-theta (Caenorhabditis elegans)
Autophosphorylation of PKC-theta (Drosophila melanogaster)
Autophosphorylation of PKC-theta (Sus scrofa)
Autophosphorylation of PKC-theta (Bos taurus)
Autophosphorylation of PKC-theta (Canis familiaris)
Autophosphorylation of PKC-theta (Rattus norvegicus)
Autophosphorylation of PKC-theta (Mus musculus)
Phosphorylation of PKC-theta (Sus scrofa)
Phosphorylation of PKC-theta (Bos taurus)
Phosphorylation of PKC-theta (Canis familiaris)
Phosphorylation of PKC-theta (Rattus norvegicus)
Phosphorylation of PKC-theta (Mus musculus)
Phosphorylation of PKC-theta (Homo sapiens)
Autophosphorylation of PKC-theta (Homo sapiens)
Phosphorylation of CARMA1 by PKC-theta (Homo sapiens)
Activation of TAK1 complex bound to pUb-TRAF6 (Homo sapiens)
Phosphorylation of IKK-beta by TAK1 (Homo sapiens)
Activation of IKK complex (Sus scrofa)
Activation of IKK complex (Bos taurus)
Activation of IKK complex (Canis familiaris)
Activation of IKK complex (Mus musculus)
Activation of IKK complex (Homo sapiens)
Activation of IKK complex (Rattus norvegicus)
Activation of TAK1-TAB2 complex (Gallus gallus)
Activation of TAK1-TAB2 complex (Sus scrofa)
Activation of TAK1-TAB2 complex (Bos taurus)
Activation of TAK1-TAB2 complex (Canis familiaris)
Activation of TAK1-TAB2 complex (Mus musculus)
Activation of TAK1-TAB2 complex (Homo sapiens)
Activation of TAK1-TAB2 complex (Rattus norvegicus)
FRK phosphorylates PTEN (Caenorhabditis elegans)
FRK phosphorylates PTEN (Drosophila melanogaster)
FRK phosphorylates PTEN (Gallus gallus)
FRK phosphorylates PTEN (Xenopus tropicalis)
FRK phosphorylates PTEN (Sus scrofa)
FRK phosphorylates PTEN (Bos taurus)
FRK phosphorylates PTEN (Canis familiaris)
FRK phosphorylates PTEN (Rattus norvegicus)
FRK phosphorylates PTEN (Mus musculus)
FRK phosphorylates PTEN (Homo sapiens)
Casein kinase II phosphorylates PTEN (Saccharomyces cerevisiae)
Casein kinase II phosphorylates PTEN (Schizosaccharomyces pombe)
Casein kinase II phosphorylates PTEN (Dictyostelium discoideum)
Casein kinase II phosphorylates PTEN (Caenorhabditis elegans)
Casein kinase II phosphorylates PTEN (Drosophila melanogaster)
Casein kinase II phosphorylates PTEN (Sus scrofa)
Casein kinase II phosphorylates PTEN (Bos taurus)
Casein kinase II phosphorylates PTEN (Canis familiaris)
Casein kinase II phosphorylates PTEN (Rattus norvegicus)
Casein kinase II phosphorylates PTEN (Mus musculus)
Casein kinase II phosphorylates PTEN (Homo sapiens)
MAPKs phosphorylate PP2A (Danio rerio)
MAPKs phosphorylate PP2A (Sus scrofa)
MAPKs phosphorylate PP2A (Bos taurus)
MAPKs phosphorylate PP2A (Canis familiaris)
MAPKs phosphorylate PP2A (Rattus norvegicus)
MAPKs phosphorylate PP2A (Mus musculus)
MAPKs phosphorylate PP2A (Homo sapiens)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Caenorhabditis elegans)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Drosophila melanogaster)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Sus scrofa)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Bos taurus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Canis familiaris)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Rattus norvegicus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Mus musculus)
Inhibition of PP2A activity by phosphorylation of the catalytic subunit at tyrosine Y307 (Homo sapiens)
AKT phosphorylates caspase-9 (Caenorhabditis elegans)
AKT phosphorylates caspase-9 (Drosophila melanogaster)
AKT phosphorylates caspase-9 (Gallus gallus)
AKT phosphorylates caspase-9 (Danio rerio)
AKT phosphorylates caspase-9 (Rattus norvegicus)
AKT phosphorylates caspase-9 (Mus musculus)
AKT phosphorylates caspase-9 (Homo sapiens)
AKT phosphorylates MKRN1 (Schizosaccharomyces pombe)
AKT phosphorylates MKRN1 (Dictyostelium discoideum)
AKT phosphorylates MKRN1 (Caenorhabditis elegans)
AKT phosphorylates MKRN1 (Drosophila melanogaster)
AKT phosphorylates MKRN1 (Gallus gallus)
AKT phosphorylates MKRN1 (Danio rerio)
AKT phosphorylates MKRN1 (Rattus norvegicus)
AKT phosphorylates MKRN1 (Mus musculus)
AKT phosphorylates MKRN1 (Homo sapiens)
AKT phosphorylates AKT1S1 (PRAS40) (Drosophila melanogaster)
AKT phosphorylates AKT1S1 (PRAS40) (Rattus norvegicus)
AKT phosphorylates AKT1S1 (PRAS40) (Mus musculus)
AKT phosphorylates AKT1S1 (PRAS40) (Homo sapiens)
AKT phosphorylates TSC2, inhibiting it (Schizosaccharomyces pombe)
AKT phosphorylates TSC2, inhibiting it (Dictyostelium discoideum)
AKT phosphorylates TSC2, inhibiting it (Drosophila melanogaster)
AKT phosphorylates TSC2, inhibiting it (Gallus gallus)
AKT phosphorylates TSC2, inhibiting it (Rattus norvegicus)
AKT phosphorylates TSC2, inhibiting it (Mus musculus)
AKT phosphorylates TSC2, inhibiting it (Homo sapiens)
AKT phosphorylates IKKalpha (Drosophila melanogaster)
AKT phosphorylates IKKalpha (Gallus gallus)
AKT phosphorylates IKKalpha (Danio rerio)
AKT phosphorylates IKKalpha (Rattus norvegicus)
AKT phosphorylates IKKalpha (Mus musculus)
AKT phosphorylates IKKalpha (Homo sapiens)
Akt1 phosphorylates GSK3 (Rattus norvegicus)
AKT phosphorylates GSK3 (Homo sapiens)
CASP9 is phosphorylated at T412 (Drosophila melanogaster)
CASP9 is phosphorylated at T412 (Gallus gallus)
CASP9 is phosphorylated at T412 (Xenopus tropicalis)
CASP9 is phosphorylated at T412 (Danio rerio)
CASP9 is phosphorylated at T412 (Sus scrofa)
CASP9 is phosphorylated at T412 (Bos taurus)
CASP9 is phosphorylated at T412 (Canis familiaris)
CASP9 is phosphorylated at T412 (Rattus norvegicus)
CASP9 is phosphorylated at T412 (Mus musculus)
CASP9 is phosphorylated at T412 (Homo sapiens)
JAK1 phosphorylates STAT3,STAT6 (Gallus gallus)
JAK1 phosphorylates STAT3,STAT6 (Sus scrofa)
JAK1 phosphorylates STAT3,STAT6 (Bos taurus)
JAK1 phosphorylates STAT3,STAT6 (Canis familiaris)
JAK1 phosphorylates STAT3,STAT6 (Rattus norvegicus)
JAK1 phosphorylates STAT3,STAT6 (Mus musculus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Gallus gallus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Sus scrofa)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Bos taurus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Canis familiaris)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Rattus norvegicus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Mus musculus)
IL4R, IL2RG, JAK1 in IL4-bound IL4R1:JAK1 are phosphorylated (Homo sapiens)
JAK1 phosphorylates STAT3,STAT6 (Homo sapiens)
Phosphorylation of BIM by JNK (Gallus gallus)
Phosphorylation of BIM by JNK (Sus scrofa)
Phosphorylation of BIM by JNK (Bos taurus)
Phosphorylation of BIM by JNK (Canis familiaris)
Phosphorylation of BIM by JNK (Rattus norvegicus)
Phosphorylation of BIM by JNK (Mus musculus)
Phosphorylation of BIM by JNK (Homo sapiens)
AKT phosphorylates Bad (Homo sapiens)
AKT phosphorylates BAD (Homo sapiens)
Phosphorylation of DLC2 by MAPK8 (Gallus gallus)
Phosphorylation of DLC2 by MAPK8 (Sus scrofa)
Phosphorylation of DLC2 by MAPK8 (Bos taurus)
Phosphorylation of DLC2 by MAPK8 (Canis familiaris)
Phosphorylation of DLC2 by MAPK8 (Rattus norvegicus)
Phosphorylation of DLC2 by MAPK8 (Mus musculus)
Phosphorylation of DLC2 by MAPK8 (Homo sapiens)
Autophosphorylation of PAK-2p34 (Oryctolagus cuniculus)
Autophosphorylation of PAK-2p34 in the activation loop (Homo sapiens)
Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 (Oryctolagus cuniculus)
Partial autophosphorylation of PAK-2 at Ser-19, Ser-20, Ser-55, Ser-192, and Ser-197 (Homo sapiens)
Cleavage of Procaspase-7 by the apoptosome (Gallus gallus)
Cleavage of Procaspase-7 by the apoptosome (Xenopus tropicalis)
Cleavage of Procaspase-7 by the apoptosome (Danio rerio)
Cleavage of Procaspase-7 by the apoptosome (Sus scrofa)
Cleavage of Procaspase-7 by the apoptosome (Bos taurus)
Cleavage of Procaspase-7 by the apoptosome (Canis familiaris)
Cleavage of Procaspase-7 by the apoptosome (Rattus norvegicus)
Cleavage of Procaspase-7 by the apoptosome (Mus musculus)
Cleavage of Procaspase-7 by the apoptosome (Homo sapiens)
Cleavage of Procaspase-3 by the apoptosome (Drosophila melanogaster)
Cleavage of Procaspase-3 by the apoptosome (Gallus gallus)
Cleavage of Procaspase-3 by the apoptosome (Xenopus tropicalis)
Cleavage of Procaspase-3 by the apoptosome (Danio rerio)
Cleavage of Procaspase-3 by the apoptosome (Sus scrofa)
Cleavage of Procaspase-3 by the apoptosome (Bos taurus)
Cleavage of Procaspase-3 by the apoptosome (Canis familiaris)
Cleavage of Procaspase-3 by the apoptosome (Rattus norvegicus)
Cleavage of Procaspase-3 by the apoptosome (Mus musculus)
Cleavage of Procaspase‑9 to caspase‑9 (Drosophila melanogaster)
Cleavage of Procaspase‑9 to caspase‑9 (Gallus gallus)
Cleavage of Procaspase‑9 to caspase‑9 (Xenopus tropicalis)
Cleavage of Procaspase‑9 to caspase‑9 (Danio rerio)
Cleavage of Procaspase‑9 to caspase‑9 (Sus scrofa)
Cleavage of Procaspase‑9 to caspase‑9 (Bos taurus)
Cleavage of Procaspase‑9 to caspase‑9 (Canis familiaris)
Cleavage of Procaspase‑9 to caspase‑9 (Rattus norvegicus)
Cleavage of Procaspase‑9 to caspase‑9 (Mus musculus)
CYCS binds to APAF1 (Drosophila melanogaster)
CYCS binds to APAF1 (Gallus gallus)
CYCS binds to APAF1 (Xenopus tropicalis)
CYCS binds to APAF1 (Danio rerio)
CYCS binds to APAF1 (Sus scrofa)
CYCS binds to APAF1 (Bos taurus)
CYCS binds to APAF1 (Canis familiaris)
CYCS binds to APAF1 (Rattus norvegicus)
CYCS binds to APAF1 (Mus musculus)
CYCS binds to APAF1 (Homo sapiens)
Cleavage of Procaspase‑9 to caspase‑9 (Homo sapiens)
Cleavage of Procaspase-3 by the apoptosome (Homo sapiens)
Activation of caspase-3 (Sus scrofa)
Activation of caspase-3 (Bos taurus)
Activation of caspase-3 (Canis familiaris)
Activation of caspase-3 (Rattus norvegicus)
Activation of caspase-3 (Mus musculus)
Activation of caspase-3 (Homo sapiens)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Plasmodium falciparum)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Danio rerio)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Plasmodium falciparum)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Danio rerio)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Plasmodium falciparum)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Saccharomyces cerevisiae)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Saccharomyces cerevisiae)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Schizosaccharomyces pombe)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Caenorhabditis elegans)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Caenorhabditis elegans)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Drosophila melanogaster)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Drosophila melanogaster)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Drosophila melanogaster)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Drosophila melanogaster)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Gallus gallus)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Gallus gallus)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Gallus gallus)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Gallus gallus)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Xenopus tropicalis)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Xenopus tropicalis)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Sus scrofa)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Sus scrofa)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Sus scrofa)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Sus scrofa)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Bos taurus)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Bos taurus)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Bos taurus)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Bos taurus)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Canis familiaris)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Canis familiaris)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Canis familiaris)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Canis familiaris)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Rattus norvegicus)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Rattus norvegicus)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Rattus norvegicus)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Mus musculus)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Mus musculus)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Mus musculus)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Mus musculus)
IP6 is phosphorylated to 1-PP-IP5 by PPIP5K1/2 in the cytosol (Homo sapiens)
1-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by IP6K1/3 in the cytosol (Homo sapiens)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Gallus gallus)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Xenopus tropicalis)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Danio rerio)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Sus scrofa)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Bos taurus)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Canis familiaris)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Rattus norvegicus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Plasmodium falciparum)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Saccharomyces cerevisiae)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Schizosaccharomyces pombe)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Dictyostelium discoideum)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Caenorhabditis elegans)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Drosophila melanogaster)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Gallus gallus)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Xenopus tropicalis)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Danio rerio)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Sus scrofa)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Bos taurus)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Canis familiaris)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Rattus norvegicus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Homo sapiens)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4,5,6)P5 is phosphorylated to 5-PP-IP4 by IP6K1/3 in the cytosol (Mus musculus)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Mus musculus)
I(1,3,4,5,6)P5 is phosphorylated to IP6 by IPPK in the cytosol (Homo sapiens)
IP6 is phosphorylated to 5-PP-IP5 by IP6K1/3 in the cytosol (Homo sapiens)
5-PP-IP5 is phosphorylated to 1,5-(PP)2-IP4 by PPIP5K1/2 in the cytosol (Homo sapiens)
I(3,4,5,6)P4 is phosphorylated to I(1,3,4,5,6)P5 by ITPK1 in the cytosol (Homo sapiens)
RIPK3 phosphorylates MLKL (Sus scrofa)
RIPK3 phosphorylates MLKL (Bos taurus)
RIPK3 phosphorylates MLKL (Rattus norvegicus)
RIPK3 phosphorylates MLKL (Mus musculus)
RIPK3 phosphorylates MLKL (Homo sapiens)
RIPK1 is phosphorylated (Sus scrofa)
RIPK1 is phosphorylated (Bos taurus)
RIPK1 is phosphorylated (Canis familiaris)
RIPK1 is phosphorylated (Rattus norvegicus)
RIPK1 is phosphorylated (Mus musculus)
RIPK1 is phosphorylated (Homo sapiens)
RIPK3 is phosphorylated (Sus scrofa)
RIPK3 is phosphorylated (Bos taurus)
RIPK3 is phosphorylated (Canis familiaris)
RIPK3 is phosphorylated (Rattus norvegicus)
RIPK3 is phosphorylated (Mus musculus)
RIPK3 is phosphorylated (Homo sapiens)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Gallus gallus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Sus scrofa)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Bos taurus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Canis familiaris)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Rattus norvegicus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Mus musculus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Gallus gallus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Sus scrofa)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Canis familiaris)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Rattus norvegicus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Mus musculus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Homo sapiens)
TBK1 is phosphorylated within the activated TLR4 complex (Gallus gallus)
TBK1 is phosphorylated within the activated TLR4 complex (Sus scrofa)
TBK1 is phosphorylated within the activated TLR4 complex (Bos taurus)
TBK1 is phosphorylated within the activated TLR4 complex (Canis familiaris)
TBK1 is phosphorylated within the activated TLR4 complex (Rattus norvegicus)
TBK1 is phosphorylated within the activated TLR4 complex (Mus musculus)
TBK1 is phosphorylated within the activated TLR4 complex (Homo sapiens)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Homo sapiens)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Gallus gallus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Sus scrofa)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Bos taurus)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Canis familiaris)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Mus musculus)
IKKbeta is activated (Gallus gallus)
IKKbeta is activated (Sus scrofa)
IKKbeta is activated (Bos taurus)
IKKbeta is activated (Canis familiaris)
IKKbeta is activated (Rattus norvegicus)
IKKbeta is activated (Mus musculus)
Irak is activated (Rattus norvegicus)
IRAK is activated (Homo sapiens)
IKKbeta is activated (Homo sapiens)
IKKbeta phosphorylates IkB causing NF-kB to dissociate (Homo sapiens)
Phosphorylation of IKKs complex mediated by MEKK1 (Gallus gallus)
Activation of recruited TAK1 (Gallus gallus)
Phosphorylation of Bcl10 (Gallus gallus)
Phosphorylation of Bcl10 (Sus scrofa)
Phosphorylation of Bcl10 (Bos taurus)
Phosphorylation of Bcl10 (Canis familiaris)
Phosphorylation of Bcl10 (Rattus norvegicus)
Phosphorylation of Bcl10 (Mus musculus)
Phosphorylation of CARMA1 (Sus scrofa)
Phosphorylation of CARMA1 (Bos taurus)
Phosphorylation of CARMA1 (Canis familiaris)
Phosphorylation of CARMA1 (Rattus norvegicus)
Phosphorylation of CARMA1 (Mus musculus)
Phosphorylation of PKC theta (Saccharomyces cerevisiae)
Phosphorylation of PKC theta (Schizosaccharomyces pombe)
Phosphorylation of PKC theta (Dictyostelium discoideum)
Phosphorylation of PKC theta (Caenorhabditis elegans)
Phosphorylation of PKC theta (Drosophila melanogaster)
Phosphorylation of PKC theta (Sus scrofa)
Phosphorylation of PKC theta (Bos taurus)
Phosphorylation of PKC theta (Canis familiaris)
Phosphorylation of PKC theta (Rattus norvegicus)
Phosphorylation of PKC theta (Mus musculus)
Change of PKC theta conformation (Sus scrofa)
Change of PKC theta conformation (Bos taurus)
Change of PKC theta conformation (Canis familiaris)
Change of PKC theta conformation (Rattus norvegicus)
Change of PKC theta conformation (Mus musculus)
Phosphorylation of PIP2 to PIP3 by PI3K (Drosophila melanogaster)
Phosphorylation of PIP2 to PIP3 by PI3K (Gallus gallus)
Phosphorylation of PIP2 to PIP3 by PI3K (Xenopus tropicalis)
Phosphorylation of PIP2 to PIP3 by PI3K (Sus scrofa)
Phosphorylation of PIP2 to PIP3 by PI3K (Bos taurus)
Phosphorylation of PIP2 to PIP3 by PI3K (Canis familiaris)
Phosphorylation of PIP2 to PIP3 by PI3K (Rattus norvegicus)
Phosphorylation of PIP2 to PIP3 by PI3K (Mus musculus)
Phosphorylation of Gab2 by Syk/Fyn (Mus musculus)
Phosphorylation of NTAL by p-SYK/Lyn (Sus scrofa)
Phosphorylation of NTAL by p-SYK/Lyn (Bos taurus)
Phosphorylation of NTAL by p-SYK/Lyn (Canis familiaris)
Phosphorylation of NTAL by p-SYK/Lyn (Rattus norvegicus)
Phosphorylation of NTAL by p-SYK/Lyn (Mus musculus)
Phosphorylation of syk (Rattus norvegicus)
Phosphorylation of beta and gamma subunits by LYN (Sus scrofa)
Phosphorylation of beta and gamma subunits by LYN (Bos taurus)
Phosphorylation of beta and gamma subunits by LYN (Canis familiaris)
Phosphorylation of beta and gamma subunits by LYN (Rattus norvegicus)
Phosphorylation of beta and gamma subunits by LYN (Mus musculus)
Autophosphorylation of LYN kinase (Caenorhabditis elegans)
Autophosphorylation of LYN kinase (Drosophila melanogaster)
Autophosphorylation of LYN kinase (Gallus gallus)
Autophosphorylation of LYN kinase (Xenopus tropicalis)
Autophosphorylation of LYN kinase (Sus scrofa)
Autophosphorylation of LYN kinase (Bos taurus)
Autophosphorylation of LYN kinase (Canis familiaris)
Autophosphorylation of LYN kinase (Rattus norvegicus)
Autophosphorylation of LYN kinase (Mus musculus)
Autophosphorylation of LYN kinase (Homo sapiens)
Phosphorylation of beta and gamma subunits by LYN (Homo sapiens)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Gallus gallus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Sus scrofa)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Bos taurus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Canis familiaris)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Rattus norvegicus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Mus musculus)
Sequestering and phosphorylation Fc gamma receptors in the lipid rafts (Homo sapiens)
Phosphorylation of SYK (Homo sapiens)
Phosphorylation of NTAL by p-SYK/Lyn (Homo sapiens)
Phosphorylation of GAB2 by SYK/FYN (Homo sapiens)
Phosphorylation of PIP2 to PIP3 by PI3K (Homo sapiens)
Change of PKC theta conformation (Homo sapiens)
Phosphorylation of PKC theta (Homo sapiens)
Phosphorylation of CARMA1 (Homo sapiens)
Phosphorylation of Bcl10 (Homo sapiens)
Activation of recruited TAK1 within the complex p-IRAK2: pUb-TRAF6:TAB2/TAB3:TAB1:TAK1 (Gallus gallus)
Phosphorylation of IKKs complex by activated TAK1 (Gallus gallus)
chicken RIP1 facilitates IKKs complex activation (Gallus gallus)
activated IKKs phosphorylates IkB alpha causing the NFkB complex to dissociate from the phospho-IkB (Gallus gallus)
Inactivation of MAP2K1 by CDK1 (Caenorhabditis elegans)
Inactivation of MAP2K1 by CDK1 (Drosophila melanogaster)
Inactivation of MAP2K1 by CDK1 (Gallus gallus)
Inactivation of MAP2K1 by CDK1 (Danio rerio)
Inactivation of MAP2K1 by CDK1 (Bos taurus)
Inactivation of MAP2K1 by CDK1 (Rattus norvegicus)
Inactivation of MAP2K1 by CDK1 (Mus musculus)
Inactivation of MAP2K1 by CDK1 (Homo sapiens)
IRAK1 phosphorylates Pellino (Drosophila melanogaster)
IRAK1 phosphorylates Pellino (Sus scrofa)
IRAK1 phosphorylates Pellino (Bos taurus)
IRAK1 phosphorylates Pellino (Canis familiaris)
IRAK1 phosphorylates Pellino (Rattus norvegicus)
IRAK1 phosphorylates Pellino (Mus musculus)
IRAK1 phosphorylates Pellino (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR 7/8 or 9 (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88: activated TLR 7/8 or 9 (Homo sapiens)
Multiple IRAK1 autophosphorylation steps within the complex pIRAK4:MyD88:activated TLR7/8 or 9 (Homo sapiens)
IRAK4 autophosphorylation in the complex with MyD88:activated TLR 7/8 or 9 (Homo sapiens)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomer:activated TLR 7/8 or 9 (Homo sapiens)
Phosphorylation and release of IRF7 upon TLR7/8 or 9 activation (Homo sapiens)
Phosphorylation and release of IRF7 (Homo sapiens)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Sus scrofa)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Bos taurus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Canis familiaris)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Mus musculus)
RIP1 facilitates IKK complex phosphorylation (Homo sapiens)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Drosophila melanogaster)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Sus scrofa)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Bos taurus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Canis familiaris)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Rattus norvegicus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Mus musculus)
Active IKBKB phosphorylates NF-kappa-B inhibitor (Homo sapiens)
Active IKK Complex phosphorylates NF-kappa-B inhibitor (Homo sapiens)
Activation of IKK by MEKK1 (Homo sapiens)
Phosphorylation and release of IRF3/IRF7 (Homo sapiens)
Activation of p38 MAPK (Dictyostelium discoideum)
Activation of p38 MAPK (Caenorhabditis elegans)
Activation of p38 MAPK (Drosophila melanogaster)
Activation of p38 MAPK (Xenopus tropicalis)
Activation of p38 MAPK (Danio rerio)
Activation of p38 MAPK (Sus scrofa)
Activation of p38 MAPK (Bos taurus)
Activation of p38 MAPK (Canis familiaris)
Activation of p38 MAPK (Rattus norvegicus)
Activation of p38 MAPK (Mus musculus)
Activation of p38 MAPK (Homo sapiens)
TAK1 phosphorylates MKK6 (Gallus gallus)
TAK1 phosphorylates MKK6 (Xenopus tropicalis)
TAK1 phosphorylates MKK6 (Sus scrofa)
TAK1 phosphorylates MKK6 (Bos taurus)
TAK1 phosphorylates MKK6 (Canis familiaris)
TAK1 phosphorylates MKK6 (Rattus norvegicus)
TAK1 phosphorylates MKK6 (Mus musculus)
TAK1 phosphorylates MKK6 (Homo sapiens)
Phosphorylation of Cx43 by c-src (Gallus gallus)
Phosphorylation of Cx43 by c-src (Sus scrofa)
Phosphorylation of Cx43 by c-src (Bos taurus)
Phosphorylation of Cx43 by c-src (Canis familiaris)
Phosphorylation of Cx43 by c-src (Rattus norvegicus)
Phosphorylation of Cx43 by c-src (Mus musculus)
Phosphorylation of Cx43 by c-src (Homo sapiens)
TBK1, IKBKE are autophosphorylated at Ser172 (Homo sapiens)
Phosphorylation of STAT2 (Gallus gallus)
Phosphorylation of STAT2 (Xenopus tropicalis)
Phosphorylation of STAT2 (Sus scrofa)
Phosphorylation of STAT2 (Bos taurus)
Phosphorylation of STAT2 (Canis familiaris)
Phosphorylation of STAT2 (Rattus norvegicus)
Phosphorylation of STAT2 (Mus musculus)
Phosphorylation of INFAR1 by TYK2 (Gallus gallus)
Phosphorylation of INFAR1 by TYK2 (Xenopus tropicalis)
Phosphorylation of INFAR1 by TYK2 (Sus scrofa)
Phosphorylation of INFAR1 by TYK2 (Bos taurus)
Phosphorylation of INFAR1 by TYK2 (Canis familiaris)
Phosphorylation of INFAR1 by TYK2 (Rattus norvegicus)
Phosphorylation of INFAR1 by TYK2 (Mus musculus)
Activation of JAK kinases (Gallus gallus)
Activation of JAK kinases (Xenopus tropicalis)
Activation of JAK kinases (Sus scrofa)
Activation of JAK kinases (Bos taurus)
Activation of JAK kinases (Canis familiaris)
Activation of JAK kinases (Rattus norvegicus)
Activation of JAK kinases (Mus musculus)
Activation of JAK kinases (Homo sapiens)
Phosphorylation of INFAR1 by TYK2 (Homo sapiens)
Phosphorylation of STAT2 (Homo sapiens)
Phosphorylation of STAT1 (Homo sapiens)
Transport of Antigen peptide in to ER (Schizosaccharomyces pombe)
Transport of Antigen peptide in to ER (Caenorhabditis elegans)
Transport of Antigen peptide in to ER (Sus scrofa)
Transport of Antigen peptide in to ER (Bos taurus)
Transport of Antigen peptide in to ER (Rattus norvegicus)
Transport of Antigen peptide in to ER (Mus musculus)
Transport of Antigen peptide in to ER (Homo sapiens)
nsp13 helicase melts secondary structures in SARS-CoV-1 genomic RNA template (Homo sapiens)
nsp13 helicase melts secondary structures in SARS-CoV-2 genomic RNA template (Homo sapiens)
GSK3 phosphorylates Nucleoprotein (Homo sapiens)
SRPK1/2 phosphorylates nucleoprotein (Homo sapiens)
GSK3 phosphorylates nucleoprotein (Homo sapiens)
CSNK1A1 phosphorylates nucleoprotein (Homo sapiens)
Unknown kinase phosphorylates nucleoprotein (Homo sapiens)
TGFBR2 phosphorylates Pard6a (Homo sapiens)
TGFBR2 phosphorylates TGFBR1 and PARD6A (Homo sapiens)
JAK2-activated MAPKs phosphorylate YBX1 (Caenorhabditis elegans)
JAK2-activated MAPKs phosphorylate YBX1 (Drosophila melanogaster)
JAK2-activated MAPKs phosphorylate YBX1 (Gallus gallus)
JAK2-activated MAPKs phosphorylate YBX1 (Xenopus tropicalis)
JAK2-activated MAPKs phosphorylate YBX1 (Danio rerio)
JAK2-activated MAPKs phosphorylate YBX1 (Sus scrofa)
JAK2-activated MAPKs phosphorylate YBX1 (Bos taurus)
JAK2-activated MAPKs phosphorylate YBX1 (Canis familiaris)
JAK2-activated MAPKs phosphorylate YBX1 (Rattus norvegicus)
JAK2-activated MAPKs phosphorylate YBX1 (Mus musculus)
JAK2-activated MAPKs phosphorylate YBX1 (Homo sapiens)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Caenorhabditis elegans)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Drosophila melanogaster)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Gallus gallus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Xenopus tropicalis)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Danio rerio)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Sus scrofa)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Bos taurus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Canis familiaris)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Rattus norvegicus)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Mus musculus)
JAK1-activated RAF1 phosphorylates MAPKs (Gallus gallus)
JAK1-activated RAF1 phosphorylates MAPKs (Sus scrofa)
JAK1-activated RAF1 phosphorylates MAPKs (Bos taurus)
JAK1-activated RAF1 phosphorylates MAPKs (Canis familiaris)
JAK1-activated RAF1 phosphorylates MAPKs (Rattus norvegicus)
JAK1-activated RAF1 phosphorylates MAPKs (Mus musculus)
JAK1-mediated phosphorylation of RAF1 (Gallus gallus)
JAK1-mediated phosphorylation of RAF1 (Sus scrofa)
JAK1-mediated phosphorylation of RAF1 (Bos taurus)
JAK1-mediated phosphorylation of RAF1 (Canis familiaris)
JAK1-mediated phosphorylation of RAF1 (Rattus norvegicus)
JAK1-mediated phosphorylation of RAF1 (Mus musculus)
JAK1-mediated phosphorylation of RAF1 (Homo sapiens)
JAK1-activated RAF1 phosphorylates MAPKs (Homo sapiens)
MAPK1 and MAPK3 phosphorylate SMAD2 and SMAD3 (Homo sapiens)
ERK5 is activated (Rattus norvegicus)
ERK5 is activated (Homo sapiens)
ORC6 is phosphorylated on T195 (Schizosaccharomyces pombe)
ORC6 is phosphorylated on T195 (Drosophila melanogaster)
ORC6 is phosphorylated on T195 (Gallus gallus)
ORC6 is phosphorylated on T195 (Xenopus tropicalis)
ORC6 is phosphorylated on T195 (Sus scrofa)
ORC6 is phosphorylated on T195 (Bos taurus)
ORC6 is phosphorylated on T195 (Canis familiaris)
ORC6 is phosphorylated on T195 (Rattus norvegicus)
ORC6 is phosphorylated on T195 (Mus musculus)
ORC6 is phosphorylated on T195 (Homo sapiens)
AKT phosphorylates p21Cip1 and p27Kip1 (Caenorhabditis elegans)
AKT phosphorylates p21Cip1 and p27Kip1 (Drosophila melanogaster)
AKT phosphorylates p21Cip1 and p27Kip1 (Gallus gallus)
AKT phosphorylates p21Cip1 and p27Kip1 (Danio rerio)
AKT phosphorylates p21Cip1 and p27Kip1 (Rattus norvegicus)
AKT phosphorylates p21Cip1 and p27Kip1 (Mus musculus)
AKT phosphorylates p21Cip1 and p27Kip1 (Homo sapiens)
AKT phosphorylates MDM2 (Gallus gallus)
AKT phosphorylates MDM2 (Danio rerio)
AKT phosphorylates MDM2 (Rattus norvegicus)
AKT phosphorylates MDM2 (Mus musculus)
AKT phosphorylates MDM2 (Homo sapiens)
SGK1 phosphorylates MDM2 (Gallus gallus)
SGK1 phosphorylates MDM2 (Danio rerio)
SGK1 phosphorylates MDM2 (Sus scrofa)
SGK1 phosphorylates MDM2 (Canis familiaris)
SGK1 phosphorylates MDM2 (Rattus norvegicus)
SGK1 phosphorylates MDM2 (Mus musculus)
PDPK1 phosphorylates SGK1 (Saccharomyces cerevisiae)
PDPK1 phosphorylates SGK1 (Schizosaccharomyces pombe)
PDPK1 phosphorylates SGK1 (Dictyostelium discoideum)
PDPK1 phosphorylates SGK1 (Caenorhabditis elegans)
PDPK1 phosphorylates SGK1 (Gallus gallus)
PDPK1 phosphorylates SGK1 (Danio rerio)
PDPK1 phosphorylates SGK1 (Sus scrofa)
PDPK1 phosphorylates SGK1 (Canis familiaris)
PDPK1 phosphorylates SGK1 (Rattus norvegicus)
PDPK1 phosphorylates SGK1 (Mus musculus)
TORC2 complex phosphorylates SGK1 (Saccharomyces cerevisiae)
TORC2 complex phosphorylates SGK1 (Schizosaccharomyces pombe)
TORC2 complex phosphorylates SGK1 (Dictyostelium discoideum)
TORC2 complex phosphorylates SGK1 (Caenorhabditis elegans)
TORC2 complex phosphorylates SGK1 (Gallus gallus)
TORC2 complex phosphorylates SGK1 (Sus scrofa)
TORC2 complex phosphorylates SGK1 (Canis familiaris)
TORC2 complex phosphorylates SGK1 (Rattus norvegicus)
TORC2 complex phosphorylates SGK1 (Mus musculus)
TORC2 complex phosphorylates SGK1 (Homo sapiens)
PDPK1 phosphorylates SGK1 (Homo sapiens)
SGK1 phosphorylates MDM2 (Homo sapiens)
p-T774-PKN1 phosphorylates CDC25C (Saccharomyces cerevisiae)
p-T774-PKN1 phosphorylates CDC25C (Schizosaccharomyces pombe)
p-T774-PKN1 phosphorylates CDC25C (Dictyostelium discoideum)
p-T774-PKN1 phosphorylates CDC25C (Caenorhabditis elegans)
p-T774-PKN1 phosphorylates CDC25C (Drosophila melanogaster)
p-T774-PKN1 phosphorylates CDC25C (Sus scrofa)
p-T774-PKN1 phosphorylates CDC25C (Bos taurus)
p-T774-PKN1 phosphorylates CDC25C (Canis familiaris)
p-T774-PKN1 phosphorylates CDC25C (Rattus norvegicus)
p-T774-PKN1 phosphorylates CDC25C (Mus musculus)
PDPK1 phosphorylates PKN1,2,3 (Saccharomyces cerevisiae)
PDPK1 phosphorylates PKN1,2,3 (Schizosaccharomyces pombe)
PDPK1 phosphorylates PKN1,2,3 (Caenorhabditis elegans)
PDPK1 phosphorylates PKN1,2,3 (Drosophila melanogaster)
PDPK1 phosphorylates PKN1,2,3 (Gallus gallus)
PDPK1 phosphorylates PKN1,2,3 (Xenopus tropicalis)
PDPK1 phosphorylates PKN1,2,3 (Danio rerio)
PDPK1 phosphorylates PKN1,2,3 (Sus scrofa)
PDPK1 phosphorylates PKN1,2,3 (Bos taurus)
PDPK1 phosphorylates PKN1,2,3 (Canis familiaris)
PDPK1 phosphorylates PKN1,2,3 (Rattus norvegicus)
PDPK1 phosphorylates PKN1,2,3 (Mus musculus)
PTK6 phosphorylates PXN (Danio rerio)
PTK6 phosphorylates PXN (Sus scrofa)
PTK6 phosphorylates PXN (Bos taurus)
PTK6 phosphorylates PXN (Rattus norvegicus)
PTK6 phosphorylates PXN (Mus musculus)
PTK6 phosphorylates PXN (Homo sapiens)
PDPK1 phosphorylates PKN1,2,3 (Homo sapiens)
p-T774-PKN1 phosphorylates CDC25C (Homo sapiens)
Phosphorylation of STAT1 at Ser727 (Gallus gallus)
Phosphorylation of STAT1 at Ser727 (Danio rerio)
Phosphorylation of STAT1 at Ser727 (Sus scrofa)
Phosphorylation of STAT1 at Ser727 (Bos taurus)
Phosphorylation of STAT1 at Ser727 (Canis familiaris)
Phosphorylation of STAT1 at Ser727 (Rattus norvegicus)
Phosphorylation of STAT1 at Ser727 (Mus musculus)
Phosphorylation of STAT1 by JAK kinases (Gallus gallus)
Phosphorylation of STAT1 by JAK kinases (Danio rerio)
Phosphorylation of STAT1 by JAK kinases (Sus scrofa)
Phosphorylation of STAT1 by JAK kinases (Bos taurus)
Phosphorylation of STAT1 by JAK kinases (Canis familiaris)
Phosphorylation of STAT1 by JAK kinases (Rattus norvegicus)
Phosphorylation of STAT1 by JAK kinases (Mus musculus)
Phosphorylation of IFNGR1 by JAK kinases (Gallus gallus)
Phosphorylation of IFNGR1 by JAK kinases (Danio rerio)
Phosphorylation of IFNGR1 by JAK kinases (Sus scrofa)
Phosphorylation of IFNGR1 by JAK kinases (Bos taurus)
Phosphorylation of IFNGR1 by JAK kinases (Canis familiaris)
Phosphorylation of IFNGR1 by JAK kinases (Rattus norvegicus)
Phosphorylation of IFNGR1 by JAK kinases (Mus musculus)
Transphosphorylation of JAK1 (Gallus gallus)
Transphosphorylation of JAK1 (Danio rerio)
Transphosphorylation of JAK1 (Sus scrofa)
Transphosphorylation of JAK1 (Bos taurus)
Transphosphorylation of JAK1 (Canis familiaris)
Transphosphorylation of JAK1 (Rattus norvegicus)
Transphosphorylation of JAK1 (Mus musculus)
Phosphorylation of JAK2 (Gallus gallus)
Phosphorylation of JAK2 (Danio rerio)
Phosphorylation of JAK2 (Sus scrofa)
Phosphorylation of JAK2 (Bos taurus)
Phosphorylation of JAK2 (Canis familiaris)
Phosphorylation of JAK2 (Rattus norvegicus)
Phosphorylation of JAK2 (Mus musculus)
Phosphorylation of JAK2 (Homo sapiens)
Transphosphorylation of JAK1 (Homo sapiens)
Phosphorylation of IFNGR1 by JAK kinases (Homo sapiens)
Phosphorylation of STAT1 by JAK kinases (Homo sapiens)
Phosphorylation of STAT1 at Ser727 (Homo sapiens)
Phosphorylation of Smad2 by Nodal Receptor (Homo sapiens)
Type II Activin Receptor (ActRII/ACVR2) phosphorylates Type I Activin Receptor (ActRIB/ACVR1B) in response to NODAL (Homo sapiens)
Type II Activin Receptor (ActRIIB/ACVR2B) phosphorylates Type I Activin Receptor (ActRIC/ACVR1C) in response to NODAL (Homo sapiens)
Phosphorylation of R-SMAD2/3 by NODAL receptor (Homo sapiens)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Drosophila melanogaster)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Gallus gallus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Xenopus tropicalis)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Danio rerio)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Sus scrofa)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Bos taurus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Canis familiaris)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Rattus norvegicus)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Mus musculus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Drosophila melanogaster)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Gallus gallus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Xenopus tropicalis)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Danio rerio)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Sus scrofa)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Bos taurus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Canis familiaris)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Rattus norvegicus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Mus musculus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1B (ActRIB, ALK4) in response to Activin (Homo sapiens)
Acvr2a phosphorylates Acvr1c in response to Activin (Mus musculus)
ACVR2A,B (ActRIIA,B) phosphorylates ACVR1C (ActRIC, ALK7) in response to Activin (Homo sapiens)
Phosphorylation of SMAD2,3 by Activin:Activin Receptor (Homo sapiens)
Activated type I receptor phosphorylates SMAD2/3 directly (Caenorhabditis elegans)
Activated type I receptor phosphorylates SMAD2/3 directly (Drosophila melanogaster)
Activated type I receptor phosphorylates SMAD2/3 directly (Gallus gallus)
Activated type I receptor phosphorylates SMAD2/3 directly (Danio rerio)
Activated type I receptor phosphorylates SMAD2/3 directly (Sus scrofa)
Activated type I receptor phosphorylates SMAD2/3 directly (Bos taurus)
Activated type I receptor phosphorylates SMAD2/3 directly (Canis familiaris)
Activated type I receptor phosphorylates SMAD2/3 directly (Rattus norvegicus)
Activated type I receptor phosphorylates SMAD2/3 directly (Mus musculus)
TGFBR2 phosphorylates TGFBR1 (Caenorhabditis elegans)
TGFBR2 phosphorylates TGFBR1 (Drosophila melanogaster)
TGFBR2 phosphorylates TGFBR1 (Gallus gallus)
TGFBR2 phosphorylates TGFBR1 (Danio rerio)
TGFBR2 phosphorylates TGFBR1 (Sus scrofa)
TGFBR2 phosphorylates TGFBR1 (Bos taurus)
TGFBR2 phosphorylates TGFBR1 (Canis familiaris)
TGFBR2 phosphorylates TGFBR1 (Rattus norvegicus)
TGFBR2 phosphorylates TGFBR1 (Mus musculus)
TGFBR2 phosphorylates TGFBR1 (Homo sapiens)
Activated type I receptor phosphorylates SMAD2/3 directly (Homo sapiens)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Drosophila melanogaster)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Gallus gallus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Xenopus tropicalis)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Danio rerio)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Sus scrofa)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Bos taurus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Canis familiaris)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Rattus norvegicus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Mus musculus)
Tyrosine kinases phosphorylate Cip/Kip inhibitors bound to CDK4/6:CCND complexes (Homo sapiens)
PTK6 phosphorylates CDKN1B (Xenopus tropicalis)
PTK6 phosphorylates CDKN1B (Danio rerio)
PTK6 phosphorylates CDKN1B (Sus scrofa)
PTK6 phosphorylates CDKN1B (Bos taurus)
PTK6 phosphorylates CDKN1B (Rattus norvegicus)
PTK6 phosphorylates CDKN1B (Mus musculus)
ERBB2 promotes PTK6 autophosphorylation (Caenorhabditis elegans)
ERBB2 promotes PTK6 autophosphorylation (Danio rerio)
ERBB2 promotes PTK6 autophosphorylation (Sus scrofa)
ERBB2 promotes PTK6 autophosphorylation (Bos taurus)
ERBB2 promotes PTK6 autophosphorylation (Rattus norvegicus)
ERBB2 promotes PTK6 autophosphorylation (Mus musculus)
ERBB2 promotes PTK6 autophosphorylation (Homo sapiens)
PTK6 phosphorylates CDKN1B (Homo sapiens)
PDPK1 phosphorylates Rps6ka2 (Homo sapiens)
Rps6ka1 autophosphorylates (Rattus norvegicus)
MAPK1 phosphorylates Rps6ka1 (Homo sapiens)
ERKs phosphorylate RSKs (Homo sapiens)
RSKs autophosphorylate (Homo sapiens)
TORC2 (mTOR) phosphorylates AKT at S473 (Saccharomyces cerevisiae)
TORC2 (mTOR) phosphorylates AKT at S473 (Schizosaccharomyces pombe)
TORC2 (mTOR) phosphorylates AKT at S473 (Dictyostelium discoideum)
TORC2 (mTOR) phosphorylates AKT at S473 (Caenorhabditis elegans)
TORC2 (mTOR) phosphorylates AKT at S473 (Drosophila melanogaster)
TORC2 (mTOR) phosphorylates AKT at S473 (Gallus gallus)
TORC2 (mTOR) phosphorylates AKT at S473 (Rattus norvegicus)
TORC2 (mTOR) phosphorylates AKT at S473 (Mus musculus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Gallus gallus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Sus scrofa)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Mus musculus)
PI3K bound to TRAT1 phosphorylates PIP2 to PIP3 (Homo sapiens)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Dictyostelium discoideum)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Caenorhabditis elegans)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Drosophila melanogaster)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Gallus gallus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Xenopus tropicalis)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Danio rerio)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Sus scrofa)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Bos taurus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Canis familiaris)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Rattus norvegicus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Mus musculus)
PI3K alpha, beta, gamma convert PIP2 to PIP3 (Homo sapiens)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Dictyostelium discoideum)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Drosophila melanogaster)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Gallus gallus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Xenopus tropicalis)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Sus scrofa)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Bos taurus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Canis familiaris)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Rattus norvegicus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Mus musculus)
G beta:gamma activated PI3Kgamma converts PIP2 to PIP3 (Homo sapiens)
Cd19 is phosphorylated (Mus musculus)
CD19 is phosphorylated (Homo sapiens)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
Phosphorylation of CD28 (Gallus gallus)
Phosphorylation of CD28 (Xenopus tropicalis)
Phosphorylation of CD28 (Sus scrofa)
Phosphorylation of CD28 (Bos taurus)
Phosphorylation of CD28 (Canis familiaris)
Phosphorylation of CD28 (Rattus norvegicus)
Phosphorylation of CD28 (Mus musculus)
Phosphorylation of CD28 (Homo sapiens)
CD28 bound PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
mTORC1 phosphorylates MAF1 (Dictyostelium discoideum)
mTORC1 phosphorylates MAF1 (Caenorhabditis elegans)
mTORC1 phosphorylates MAF1 (Drosophila melanogaster)
mTORC1 phosphorylates MAF1 (Gallus gallus)
mTORC1 phosphorylates MAF1 (Danio rerio)
mTORC1 phosphorylates MAF1 (Sus scrofa)
mTORC1 phosphorylates MAF1 (Bos taurus)
mTORC1 phosphorylates MAF1 (Canis familiaris)
mTORC1 phosphorylates MAF1 (Rattus norvegicus)
mTORC1 phosphorylates MAF1 (Mus musculus)
mTORC1 phosphorylates MAF1 (Homo sapiens)
activated human TAK1 phosphorylates MKK3/MKK6 (Drosophila melanogaster)
activated human TAK1 phosphorylates MKK3/MKK6 (Gallus gallus)
activated human TAK1 phosphorylates MKK3/MKK6 (Xenopus tropicalis)
activated human TAK1 phosphorylates MKK3/MKK6 (Sus scrofa)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Canis familiaris)
activated human TAK1 phosphorylates MKK3/MKK6 (Rattus norvegicus)
activated human TAK1 phosphorylates MKK3/MKK6 (Mus musculus)
activated human TAK1 phosphorylates MKK3/MKK6 (Homo sapiens)
MAP3K5 phosphorylates MKK3 and MKK6 (Caenorhabditis elegans)
MAP3K5 phosphorylates MKK3 and MKK6 (Drosophila melanogaster)
MAP3K5 phosphorylates MKK3 and MKK6 (Gallus gallus)
MAP3K5 phosphorylates MKK3 and MKK6 (Sus scrofa)
MAP3K5 phosphorylates MKK3 and MKK6 (Bos taurus)
MAP3K5 phosphorylates MKK3 and MKK6 (Canis familiaris)
MAP3K5 phosphorylates MKK3 and MKK6 (Rattus norvegicus)
MAP3K5 phosphorylates MKK3 and MKK6 (Mus musculus)
MAP3K5 phosphorylates MKK3 and MKK6 (Homo sapiens)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Dictyostelium discoideum)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Caenorhabditis elegans)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Drosophila melanogaster)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Gallus gallus)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Danio rerio)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Sus scrofa)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Bos taurus)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Canis familiaris)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Rattus norvegicus)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Mus musculus)
Phosphorylation of MEK7 by MEKK1 (Dictyostelium discoideum)
Phosphorylation of MEK7 by MEKK1 (Canis familiaris)
Phosphorylation of MEK7 by MEKK1 (Rattus norvegicus)
Phosphorylation of MEK7 by MEKK1 (Mus musculus)
Autophosphorylation and activation of Mekk1 (Mus musculus)
Autophosphorylation of PAK (Drosophila melanogaster)
Autophosphorylation of PAK (Gallus gallus)
Autophosphorylation of PAK (Xenopus tropicalis)
Autophosphorylation of PAK (Sus scrofa)
Autophosphorylation of PAK (Bos taurus)
Autophosphorylation of PAK (Canis familiaris)
Autophosphorylation of PAK (Rattus norvegicus)
Autophosphorylation of PAK (Mus musculus)
Phosphorylation and activation of VAV (Drosophila melanogaster)
Phosphorylation and activation of VAV (Gallus gallus)
Phosphorylation and activation of VAV (Xenopus tropicalis)
Phosphorylation and activation of VAV (Sus scrofa)
Phosphorylation and activation of VAV (Bos taurus)
Phosphorylation and activation of VAV (Canis familiaris)
Phosphorylation and activation of VAV (Rattus norvegicus)
Phosphorylation and activation of VAV (Mus musculus)
Phosphorylation of SLP-76 by p-SYK (Sus scrofa)
Phosphorylation of SLP-76 by p-SYK (Bos taurus)
Phosphorylation of SLP-76 by p-SYK (Canis familiaris)
Phosphorylation of SLP-76 by p-SYK (Rattus norvegicus)
Phosphorylation of SLP-76 by p-SYK (Mus musculus)
Phosphorylation of SLP-76 by p-SYK (Homo sapiens)
Phosphorylation and activation of VAV (Homo sapiens)
Autophosphorylation of PAK (Homo sapiens)
Autophosphorylation and activation of MEKK1 (Homo sapiens)
Phosphorylation of MEK7 by MEKK1 (Homo sapiens)
Activated TAK1 phosphorylates MKK4/MKK7 (Drosophila melanogaster)
Activated TAK1 phosphorylates MKK4/MKK7 (Gallus gallus)
Activated TAK1 phosphorylates MKK4/MKK7 (Xenopus tropicalis)
Activated TAK1 phosphorylates MKK4/MKK7 (Sus scrofa)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Canis familiaris)
Activated TAK1 phosphorylates MKK4/MKK7 (Rattus norvegicus)
Activated TAK1 phosphorylates MKK4/MKK7 (Mus musculus)
Activated TAK1 phosphorylates MKK4/MKK7 (Homo sapiens)
Phosphorylation of human JNKs by activated MKK4/MKK7 (Homo sapiens)
MAP2K2 phosphorylates MAPK1 (Saccharomyces cerevisiae)
MAP2K2 phosphorylates MAPK1 (Schizosaccharomyces pombe)
MAP2K2 phosphorylates MAPK1 (Dictyostelium discoideum)
MAP2K2 phosphorylates MAPK1 (Caenorhabditis elegans)
MAP2K2 phosphorylates MAPK1 (Drosophila melanogaster)
MAP2K2 phosphorylates MAPK1 (Danio rerio)
MAP2K2 phosphorylates MAPK1 (Sus scrofa)
MAP2K2 phosphorylates MAPK1 (Bos taurus)
MAP2K2 phosphorylates MAPK1 (Canis familiaris)
MAP2K2 phosphorylates MAPK1 (Rattus norvegicus)
MAP2K2 phosphorylates MAPK1 (Mus musculus)
MAP2K2 phosphorylates MAPK1 (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Caenorhabditis elegans)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Gallus gallus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Danio rerio)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Sus scrofa)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Bos taurus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Mus musculus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Caenorhabditis elegans)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Drosophila melanogaster)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Gallus gallus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Danio rerio)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Sus scrofa)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Bos taurus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Rattus norvegicus)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Mus musculus)
BRAF autophosphorylates downstream of RAP1 and NGF (Caenorhabditis elegans)
BRAF autophosphorylates downstream of RAP1 and NGF (Drosophila melanogaster)
BRAF autophosphorylates downstream of RAP1 and NGF (Gallus gallus)
BRAF autophosphorylates downstream of RAP1 and NGF (Sus scrofa)
BRAF autophosphorylates downstream of RAP1 and NGF (Bos taurus)
BRAF autophosphorylates downstream of RAP1 and NGF (Rattus norvegicus)
BRAF autophosphorylates downstream of RAP1 and NGF (Mus musculus)
FRS2 is phosphorylated by active TrkA receptor (Gallus gallus)
FRS2 is phosphorylated by active TrkA receptor (Xenopus tropicalis)
FRS2 is phosphorylated by active TrkA receptor (Sus scrofa)
FRS2 is phosphorylated by active TrkA receptor (Bos taurus)
FRS2 is phosphorylated by active TrkA receptor (Canis familiaris)
FRS2 is phosphorylated by active TrkA receptor (Rattus norvegicus)
FRS2 is phosphorylated by active TrkA receptor (Mus musculus)
FRS2 is phosphorylated by active TrkA receptor (Homo sapiens)
BRAF autophosphorylates downstream of RAP1 and NGF (Homo sapiens)
Activated BRAF phosphorylates MAP2K dimers downstream of RAP1 and NGF (Homo sapiens)
MAP2Ks phosphorylate MAPKs downstream of BRAF and NGF (Homo sapiens)
MAP2K1 phosphorylates MAPK3 (Saccharomyces cerevisiae)
MAP2K1 phosphorylates MAPK3 (Schizosaccharomyces pombe)
MAP2K1 phosphorylates MAPK3 (Dictyostelium discoideum)
MAP2K1 phosphorylates MAPK3 (Caenorhabditis elegans)
MAP2K1 phosphorylates MAPK3 (Drosophila melanogaster)
MAP2K1 phosphorylates MAPK3 (Danio rerio)
MAP2K1 phosphorylates MAPK3 (Bos taurus)
MAP2K1 phosphorylates MAPK3 (Rattus norvegicus)
MAP2K1 phosphorylates MAPK3 (Mus musculus)
Tpl2 phosphorylates Mek1, Sek1 (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Sus scrofa)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Bos taurus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Canis familiaris)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Mus musculus)
IKBKB phosphorylates NFkB p105 within the NFkB p105:TPL2:ABIN2 complex (Homo sapiens)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Sus scrofa)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Bos taurus)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Canis familiaris)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Mus musculus)
IKBKB phosphorylates TPL2 (MAP3K8) at Ser400 (Homo sapiens)
MAP3K8 is phosphorylated (Gallus gallus)
MAP3K8 is phosphorylated (Xenopus tropicalis)
MAP3K8 is phosphorylated (Sus scrofa)
MAP3K8 is phosphorylated (Bos taurus)
MAP3K8 is phosphorylated (Canis familiaris)
MAP3K8 is phosphorylated (Mus musculus)
Activation of TAK1 complex bound to activated TLR4 complex (Gallus gallus)
Activation of TAK1 complex bound to activated TLR4 complex (Sus scrofa)
Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)
Activation of TAK1 complex bound to activated TLR4 complex (Canis familiaris)
Activation of TAK1 complex bound to activated TLR4 complex (Rattus norvegicus)
Activation of TAK1 complex bound to activated TLR4 complex (Mus musculus)
Activation of TAK1 complex bound to activated TLR4 complex (Homo sapiens)
Activation of recruited TAK1 within the activated TLR3 complex (Homo sapiens)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Gallus gallus)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Xenopus tropicalis)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Sus scrofa)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Bos taurus)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Canis familiaris)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Rattus norvegicus)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Mus musculus)
ALPK1 phosphorylates TIFA (Gallus gallus)
ALPK1 phosphorylates TIFA (Xenopus tropicalis)
ALPK1 phosphorylates TIFA (Sus scrofa)
ALPK1 phosphorylates TIFA (Bos taurus)
ALPK1 phosphorylates TIFA (Canis familiaris)
ALPK1 phosphorylates TIFA (Rattus norvegicus)
ALPK1 phosphorylates TIFA (Mus musculus)
ALPK1 phosphorylates TIFA (Homo sapiens)
Auto phosphorylation of TAK1 within the ALPK1:ADP-heptose:p-T9-TIFA:pUb-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 :MAP3K7 complex (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Gallus gallus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Xenopus tropicalis)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Sus scrofa)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Bos taurus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Canis familiaris)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Rattus norvegicus)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Mus musculus)
Phosphorylation of IRAK2 bound to the activated IRAK4:MyD88 oligomerl:activated TLR5 or 10 complex (Homo sapiens)
IRAK4 autophosphorylation within the complex activated TLR:MyD88 (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to MyD88:activated TLR complex (Homo sapiens)
Multiple IRAK1 autophosphorylation within the complex p-IRAK4:oligo MyD88:activated TLR (Homo sapiens)
TIRAP is phosphorylated by BTK (Homo sapiens)
IRAK4 autophosphorylation in the complex with activated TLR:MyD88:TIRAP (Homo sapiens)
First phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:Mal (Homo sapiens)
Second phosphorylation of IRAK1 by IRAK4 bound to activated TLR:MyD88:TIRAP (Homo sapiens)
Multiple IRAK1 autophosphorylation steps (Homo sapiens)
Auto phosphorylation of TAK1 bound to p-IRAK2:pUb oligo-TRAF6: free K63 pUb:TAB1:TAB2/TAB3 (Homo sapiens)
Activated TAK1 mediates phosphorylation of the IKK Complex (Homo sapiens)
MAP3K8 is phosphorylated (Homo sapiens)
TPL2 phosphorylates MEK1, SEK1 (Homo sapiens)
MAP2K1 phosphorylates MAPK3 (Homo sapiens)
MAP2Ks phosphorylate MAPKs (Caenorhabditis elegans)
MAP2Ks phosphorylate MAPKs (Drosophila melanogaster)
MAP2Ks phosphorylate MAPKs (Gallus gallus)
MAP2Ks phosphorylate MAPKs (Sus scrofa)
MAP2Ks phosphorylate MAPKs (Bos taurus)
MAP2Ks phosphorylate MAPKs (Canis familiaris)
MAP2Ks phosphorylate MAPKs (Rattus norvegicus)
MAP2Ks phosphorylate MAPKs (Mus musculus)
RAF phosphorylates MAP2K dimer (Caenorhabditis elegans)
RAF phosphorylates MAP2K dimer (Drosophila melanogaster)
RAF phosphorylates MAP2K dimer (Gallus gallus)
RAF phosphorylates MAP2K dimer (Sus scrofa)
RAF phosphorylates MAP2K dimer (Bos taurus)
RAF phosphorylates MAP2K dimer (Canis familiaris)
RAF phosphorylates MAP2K dimer (Rattus norvegicus)
RAF phosphorylates MAP2K dimer (Mus musculus)
Phosphorylation of RAF (Drosophila melanogaster)
Phosphorylation of RAF (Gallus gallus)
Phosphorylation of RAF (Sus scrofa)
Phosphorylation of RAF (Bos taurus)
Phosphorylation of RAF (Canis familiaris)
Phosphorylation of RAF (Rattus norvegicus)
Phosphorylation of RAF (Mus musculus)
MARK3 phosphorylates KSR1 (Plasmodium falciparum)
MARK3 phosphorylates KSR1 (Dictyostelium discoideum)
MARK3 phosphorylates KSR1 (Caenorhabditis elegans)
MARK3 phosphorylates KSR1 (Drosophila melanogaster)
MARK3 phosphorylates KSR1 (Sus scrofa)
MARK3 phosphorylates KSR1 (Bos taurus)
MARK3 phosphorylates KSR1 (Canis familiaris)
MARK3 phosphorylates KSR1 (Rattus norvegicus)
MARK3 phosphorylates KSR1 (Mus musculus)
MARK3 phosphorylates KSR1 (Homo sapiens)
FLT3LG dimer:FLT3 dimer autophosphorylates (Sus scrofa)
FLT3LG dimer:FLT3 dimer autophosphorylates (Bos taurus)
FLT3LG dimer:FLT3 dimer autophosphorylates (Canis familiaris)
FLT3LG dimer:FLT3 dimer autophosphorylates (Mus musculus)
FLT3LG dimer:FLT3 dimer autophosphorylates (Homo sapiens)
MET phosphorylates SHC1-2 (Gallus gallus)
MET phosphorylates SHC1-2 (Xenopus tropicalis)
MET phosphorylates SHC1-2 (Sus scrofa)
MET phosphorylates SHC1-2 (Bos taurus)
MET phosphorylates SHC1-2 (Canis familiaris)
MET phosphorylates SHC1-2 (Rattus norvegicus)
MET phosphorylates SHC1-2 (Mus musculus)
MET phosphorylates SHC1-2 (Homo sapiens)
Phosphorylation of SHC1 (Gallus gallus)
Phosphorylation of SHC1 (Xenopus tropicalis)
Phosphorylation of SHC1 (Sus scrofa)
Phosphorylation of SHC1 (Bos taurus)
Phosphorylation of SHC1 (Canis familiaris)
Phosphorylation of SHC1 (Rattus norvegicus)
Phosphorylation of SHC1 (Mus musculus)
Phosphorylation of SHC1 (Homo sapiens)
Tyrosine kinases phosphorylate the receptor (Gallus gallus)
Tyrosine kinases phosphorylate the receptor (Sus scrofa)
Tyrosine kinases phosphorylate the receptor (Bos taurus)
Tyrosine kinases phosphorylate the receptor (Canis familiaris)
Tyrosine kinases phosphorylate the receptor (Rattus norvegicus)
Tyrosine kinases phosphorylate the receptor (Mus musculus)
Tyrosine kinases phosphorylate the receptor (Homo sapiens)
SHC1 bound to IL2 receptor is phosphorylated (Sus scrofa)
SHC1 bound to IL2 receptor is phosphorylated (Bos taurus)
SHC1 bound to IL2 receptor is phosphorylated (Canis familiaris)
SHC1 bound to IL2 receptor is phosphorylated (Rattus norvegicus)
SHC1 bound to IL2 receptor is phosphorylated (Mus musculus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Sus scrofa)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Bos taurus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Canis familiaris)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Rattus norvegicus)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Mus musculus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Sus scrofa)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Bos taurus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Canis familiaris)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Rattus norvegicus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Mus musculus)
Within the IL-2R complex JAK3 phosphorylates JAK1 (Homo sapiens)
JAK1 phosphorylates Y338, Y392 and Y510 of IL2RB (Homo sapiens)
SHC1 bound to IL2 receptor is phosphorylated (Homo sapiens)
Phosphorylation of IRS (Gallus gallus)
Phosphorylation of IRS (Xenopus tropicalis)
Phosphorylation of IRS (Sus scrofa)
Phosphorylation of IRS (Bos taurus)
Phosphorylation of IRS (Canis familiaris)
Phosphorylation of IRS (Rattus norvegicus)
Phosphorylation of IRS (Mus musculus)
Autophosphorylation of insulin receptor (Gallus gallus)
Autophosphorylation of insulin receptor (Xenopus tropicalis)
Autophosphorylation of insulin receptor (Danio rerio)
Autophosphorylation of insulin receptor (Sus scrofa)
Autophosphorylation of insulin receptor (Bos taurus)
Autophosphorylation of insulin receptor (Canis familiaris)
Autophosphorylation of insulin receptor (Rattus norvegicus)
Autophosphorylation of insulin receptor (Mus musculus)
Autophosphorylation of insulin receptor (Homo sapiens)
Phosphorylation of IRS (Homo sapiens)
Phosphorylation of FAK by Src kinases (Mus musculus)
Recruitment of FAK to NCAM1:Fyn in lipid rafts (Mus musculus)
Autophosphorylation of NCAM1 bound Fyn (Mus musculus)
Autophosphorylation of NCAM1 bound Fyn (Homo sapiens)
Recruitment of FAK to NCAM1:Fyn in lipid rafts (Homo sapiens)
Phosphorylation of FAK by Src kinase (Homo sapiens)
Activated FGFR1 phosphorylates FRS3 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates FRS3 (Drosophila melanogaster)
Activated FGFR1 phosphorylates FRS3 (Gallus gallus)
Activated FGFR1 phosphorylates FRS3 (Xenopus tropicalis)
Activated FGFR1 phosphorylates FRS3 (Danio rerio)
Activated FGFR1 phosphorylates FRS3 (Sus scrofa)
Activated FGFR1 phosphorylates FRS3 (Bos taurus)
Activated FGFR1 phosphorylates FRS3 (Canis familiaris)
Activated FGFR1 phosphorylates FRS3 (Rattus norvegicus)
Activated FGFR1 phosphorylates FRS3 (Mus musculus)
Activated FGFR1 phosphorylates FRS3 (Homo sapiens)
Rasgrp1 and Rasgrp3 are recruited to the membrane and phosphorylated (Mus musculus)
RasGRP1 and RasGRP3 binds diacylglycerol and is phosphorylated (Homo sapiens)
SHC1 phosphorylation by ERBB2 heterodimers (Caenorhabditis elegans)
SHC1 phosphorylation by ERBB2 heterodimers (Drosophila melanogaster)
SHC1 phosphorylation by ERBB2 heterodimers (Gallus gallus)
SHC1 phosphorylation by ERBB2 heterodimers (Xenopus tropicalis)
SHC1 phosphorylation by ERBB2 heterodimers (Danio rerio)
SHC1 phosphorylation by ERBB2 heterodimers (Sus scrofa)
SHC1 phosphorylation by ERBB2 heterodimers (Bos taurus)
SHC1 phosphorylation by ERBB2 heterodimers (Canis familiaris)
SHC1 phosphorylation by ERBB2 heterodimers (Rattus norvegicus)
SHC1 phosphorylation by ERBB2 heterodimers (Mus musculus)
SHC1 phosphorylation by ERBB2 heterodimers (Homo sapiens)
MET dimers autophosphorylate (Caenorhabditis elegans)
MET dimers autophosphorylate (Gallus gallus)
MET dimers autophosphorylate (Xenopus tropicalis)
MET dimers autophosphorylate (Sus scrofa)
MET dimers autophosphorylate (Bos taurus)
MET dimers autophosphorylate (Canis familiaris)
MET dimers autophosphorylate (Rattus norvegicus)
MET dimers autophosphorylate (Mus musculus)
MET dimers autophosphorylate (Homo sapiens)
RET tyrosine phosphorylation (Gallus gallus)
RET tyrosine phosphorylation (Sus scrofa)
RET tyrosine phosphorylation (Bos taurus)
RET tyrosine phosphorylation (Canis familiaris)
RET tyrosine phosphorylation (Rattus norvegicus)
RET tyrosine phosphorylation (Mus musculus)
RET tyrosine phosphorylation (Homo sapiens)
Activated FGFR3 phosphorylates SHC1 (Drosophila melanogaster)
Activated FGFR3 phosphorylates SHC1 (Gallus gallus)
Activated FGFR3 phosphorylates SHC1 (Bos taurus)
Activated FGFR3 phosphorylates SHC1 (Canis familiaris)
Activated FGFR3 phosphorylates SHC1 (Rattus norvegicus)
Activated FGFR3 phosphorylates SHC1 (Mus musculus)
Activated FGFR3 phosphorylates SHC1 (Homo sapiens)
Trans-phosphorylation of Tie2 (Mus musculus)
Trans-phosphorylation of Tie2 (Homo sapiens)
Phosphorylation of SHC1 by ERBB4 homodimers (Drosophila melanogaster)
Phosphorylation of SHC1 by ERBB4 homodimers (Gallus gallus)
Phosphorylation of SHC1 by ERBB4 homodimers (Xenopus tropicalis)
Phosphorylation of SHC1 by ERBB4 homodimers (Sus scrofa)
Phosphorylation of SHC1 by ERBB4 homodimers (Bos taurus)
Phosphorylation of SHC1 by ERBB4 homodimers (Canis familiaris)
Phosphorylation of SHC1 by ERBB4 homodimers (Rattus norvegicus)
Phosphorylation of SHC1 by ERBB4 homodimers (Mus musculus)
Phosphorylation of SHC1 by ERBB4 homodimers (Homo sapiens)
Phosphorylation of LAT by p-SYK (Sus scrofa)
Phosphorylation of LAT by p-SYK (Canis familiaris)
Phosphorylation of LAT by p-SYK (Rattus norvegicus)
Phosphorylation of LAT by p-SYK (Mus musculus)
Phosphorylation of SYK (Gallus gallus)
Phosphorylation of SYK (Sus scrofa)
Phosphorylation of SYK (Canis familiaris)
Phosphorylation of SYK (Rattus norvegicus)
Phosphorylation of SYK (Mus musculus)
Phosphorylation of DAP12 (Mus musculus)
Phosphorylation of DAP12 (Homo sapiens)
Phosphorylation of SYK (Homo sapiens)
Phosphorylation of LAT by p-SYK (Homo sapiens)
Phosphorylation of SHC by SYK kinase (Sus scrofa)
Phosphorylation of SHC by SYK kinase (Bos taurus)
Phosphorylation of SHC by SYK kinase (Canis familiaris)
Phosphorylation of SHC by SYK kinase (Rattus norvegicus)
Phosphorylation of SHC by SYK kinase (Mus musculus)
Phosphorylation of SHC by SYK kinase (Homo sapiens)
Activated FGFR1 phosphorylates SHC1 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates SHC1 (Drosophila melanogaster)
Activated FGFR1 phosphorylates SHC1 (Gallus gallus)
Activated FGFR1 phosphorylates SHC1 (Xenopus tropicalis)
Activated FGFR1 phosphorylates SHC1 (Danio rerio)
Activated FGFR1 phosphorylates SHC1 (Sus scrofa)
Activated FGFR1 phosphorylates SHC1 (Bos taurus)
Activated FGFR1 phosphorylates SHC1 (Canis familiaris)
Activated FGFR1 phosphorylates SHC1 (Rattus norvegicus)
Activated FGFR1 phosphorylates SHC1 (Mus musculus)
Activated FGFR1 phosphorylates SHC1 (Homo sapiens)
SHC1 phosphorylation by phosphorylated EGFR (Drosophila melanogaster)
SHC1 phosphorylation by phosphorylated EGFR (Gallus gallus)
SHC1 phosphorylation by phosphorylated EGFR (Xenopus tropicalis)
SHC1 phosphorylation by phosphorylated EGFR (Sus scrofa)
SHC1 phosphorylation by phosphorylated EGFR (Bos taurus)
SHC1 phosphorylation by phosphorylated EGFR (Canis familiaris)
SHC1 phosphorylation by phosphorylated EGFR (Rattus norvegicus)
SHC1 phosphorylation by phosphorylated EGFR (Mus musculus)
SHC1 phosphorylation by phosphorylated EGFR (Homo sapiens)
Activated FGFR2 phosphorylates SHC1 (Drosophila melanogaster)
Activated FGFR2 phosphorylates SHC1 (Gallus gallus)
Activated FGFR2 phosphorylates SHC1 (Bos taurus)
Activated FGFR2 phosphorylates SHC1 (Canis familiaris)
Activated FGFR2 phosphorylates SHC1 (Rattus norvegicus)
Activated FGFR2 phosphorylates SHC1 (Mus musculus)
Activated FGFR2 phosphorylates SHC1 (Homo sapiens)
Phosphorylation of PLC-gamma (Rattus norvegicus)
Btk autophosphorylates (Mus musculus)
LYN,SYK phosphorylate BTK (Gallus gallus)
Lyn, p-Syk phosphorylate Btk (Mus musculus)
p-6Y-SYK phosphorylates BLNK (SLP65) (Gallus gallus)
p-6Y-SYK phosphorylates BLNK (SLP65) (Sus scrofa)
p-6Y-SYK phosphorylates BLNK (SLP65) (Bos taurus)
p-6Y-SYK phosphorylates BLNK (SLP65) (Canis familiaris)
p-6Y-SYK phosphorylates BLNK (SLP65) (Rattus norvegicus)
p-6Y-SYK phosphorylates BLNK (SLP65) (Mus musculus)
SYK autophosphorylates at the activated BCR (Gallus gallus)
SYK autophosphorylates at the activated BCR (Sus scrofa)
SYK autophosphorylates at the activated BCR (Bos taurus)
SYK autophosphorylates at the activated BCR (Canis familiaris)
SYK autophosphorylates at the activated BCR (Rattus norvegicus)
SYK autophosphorylates at the activated BCR (Mus musculus)
Phosphorylation of ITAMs of Ig-alpha (Cd79a) and Ig-beta (Cd79b) (Mus musculus)
LYN, FYN, BLK phosphorylate ITAMs of Ig-alpha (CD79A) and Ig-beta (CD79B) (Homo sapiens)
SYK autophosphorylates at the activated BCR (Homo sapiens)
p-6Y-SYK phosphorylates BLNK (SLP65) (Homo sapiens)
p-SYK and LYN phosphorylate BTK (Homo sapiens)
BTK autophosphorylates (Homo sapiens)
Phosphorylated BTK phosphorylates PLCG2 (Homo sapiens)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Plasmodium falciparum)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Caenorhabditis elegans)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Drosophila melanogaster)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Dictyostelium discoideum)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Dictyostelium discoideum)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Gallus gallus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Xenopus tropicalis)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Danio rerio)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Danio rerio)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Sus scrofa)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Sus scrofa)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Sus scrofa)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Bos taurus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Bos taurus)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Canis familiaris)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Canis familiaris)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Canis familiaris)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Homo sapiens)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Rattus norvegicus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(3,4,6)P3 is phosphorylated to I(1,3,4,6)P4 by ITPK1 in the cytosol (Mus musculus)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Mus musculus)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Mus musculus)
I(1,4,5)P3 is phosphorylated to I(1,3,4,5)P4 by ITPKA/B/C in the cytosol (Homo sapiens)
I(1,3,4)P3 is phosphorylated to I(1,3,4,5)P4 by ITPK1 in the cytosol (Homo sapiens)
Phosphorylation of cPLA2 by ERK-2 (Saccharomyces cerevisiae)
Phosphorylation of cPLA2 by ERK-2 (Schizosaccharomyces pombe)
Phosphorylation of cPLA2 by ERK-2 (Gallus gallus)
Phosphorylation of cPLA2 by ERK-2 (Xenopus tropicalis)
Phosphorylation of cPLA2 by ERK-2 (Danio rerio)
Phosphorylation of cPLA2 by ERK-2 (Sus scrofa)
Phosphorylation of cPLA2 by ERK-2 (Bos taurus)
Phosphorylation of cPLA2 by ERK-2 (Canis familiaris)
Phosphorylation of cPLA2 by ERK-2 (Rattus norvegicus)
Phosphorylation of cPLA2 by ERK-2 (Mus musculus)
Phosphorylation of cPLA2 by ERK-2 (Homo sapiens)
Phosphorylation of cPLA2 by MAPK p38 alpha (Saccharomyces cerevisiae)
Phosphorylation of cPLA2 by MAPK p38 alpha (Schizosaccharomyces pombe)
Phosphorylation of cPLA2 by MAPK p38 alpha (Gallus gallus)
Phosphorylation of cPLA2 by MAPK p38 alpha (Xenopus tropicalis)
Phosphorylation of cPLA2 by MAPK p38 alpha (Danio rerio)
Phosphorylation of cPLA2 by MAPK p38 alpha (Sus scrofa)
Phosphorylation of cPLA2 by MAPK p38 alpha (Bos taurus)
Phosphorylation of cPLA2 by MAPK p38 alpha (Canis familiaris)
Phosphorylation of cPLA2 by MAPK p38 alpha (Rattus norvegicus)
Phosphorylation of cPLA2 by MAPK p38 alpha (Mus musculus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Saccharomyces cerevisiae)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Schizosaccharomyces pombe)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Dictyostelium discoideum)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Caenorhabditis elegans)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Drosophila melanogaster)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Gallus gallus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Xenopus tropicalis)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Danio rerio)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Sus scrofa)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Bos taurus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Canis familiaris)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Rattus norvegicus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Mus musculus)
P2Y purinoceptor 1 activates MAP kinase p38 alpha (Homo sapiens)
Fgr may phosphorylate p38 MAPK (Caenorhabditis elegans)
Fgr may phosphorylate p38 MAPK (Drosophila melanogaster)
Fgr may phosphorylate p38 MAPK (Gallus gallus)
Fgr may phosphorylate p38 MAPK (Xenopus tropicalis)
Fgr may phosphorylate p38 MAPK (Danio rerio)
Fgr may phosphorylate p38 MAPK (Sus scrofa)
Fgr may phosphorylate p38 MAPK (Bos taurus)
Fgr may phosphorylate p38 MAPK (Canis familiaris)
Fgr may phosphorylate p38 MAPK (Rattus norvegicus)
Fgr may phosphorylate p38 MAPK (Mus musculus)
FGR binds and phosphorylates LRP8 (Gallus gallus)
FGR binds and phosphorylates LRP8 (Sus scrofa)
FGR binds and phosphorylates LRP8 (Bos taurus)
FGR binds and phosphorylates LRP8 (Canis familiaris)
FGR binds and phosphorylates LRP8 (Rattus norvegicus)
FGR binds and phosphorylates LRP8 (Mus musculus)
FGR binds and phosphorylates LRP8 (Homo sapiens)
Fgr may phosphorylate p38 MAPK (Homo sapiens)
Phosphorylation of cPLA2 by MAPK p38 alpha (Homo sapiens)
CaMKII autophosphorylates (Rattus norvegicus)
CaMKII autophosphorylates (Homo sapiens)
Re-acidification of clathrin sculpted monoamine transport vesicle lumen (Homo sapiens)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Plasmodium falciparum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Canis familiaris)
PI3K produces PIP3 and other phosphatidyl inositides (Canis familiaris)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Plasmodium falciparum)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Plasmodium falciparum)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Plasmodium falciparum)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Saccharomyces cerevisiae)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Saccharomyces cerevisiae)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Saccharomyces cerevisiae)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Schizosaccharomyces pombe)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Schizosaccharomyces pombe)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Schizosaccharomyces pombe)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Schizosaccharomyces pombe)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Dictyostelium discoideum)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Dictyostelium discoideum)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Dictyostelium discoideum)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Dictyostelium discoideum)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Dictyostelium discoideum)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Dictyostelium discoideum)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Caenorhabditis elegans)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Caenorhabditis elegans)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Caenorhabditis elegans)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Caenorhabditis elegans)
PI3K phosphorylates PIP2 to PIP3 (Caenorhabditis elegans)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Caenorhabditis elegans)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Caenorhabditis elegans)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Caenorhabditis elegans)
PI3K produces PIP3 and other phosphatidyl inositides (Drosophila melanogaster)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Drosophila melanogaster)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Drosophila melanogaster)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Drosophila melanogaster)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Drosophila melanogaster)
PI3K phosphorylates PIP2 to PIP3 (Drosophila melanogaster)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Drosophila melanogaster)
PI3K produces PIP3 and other phosphatidyl inositides (Gallus gallus)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Gallus gallus)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Gallus gallus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Gallus gallus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Gallus gallus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Gallus gallus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Gallus gallus)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Gallus gallus)
PI3K produces PIP3 and other phosphatidyl inositides (Xenopus tropicalis)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Xenopus tropicalis)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Xenopus tropicalis)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Xenopus tropicalis)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Xenopus tropicalis)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Xenopus tropicalis)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Xenopus tropicalis)
PI3K phosphorylates PIP2 to PIP3 (Danio rerio)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Danio rerio)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Danio rerio)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Danio rerio)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Danio rerio)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Danio rerio)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Danio rerio)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Danio rerio)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Danio rerio)
PI3K produces PIP3 and other phosphatidyl inositides (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Sus scrofa)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Sus scrofa)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Sus scrofa)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Sus scrofa)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Sus scrofa)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Sus scrofa)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Sus scrofa)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Sus scrofa)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Sus scrofa)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Mus musculus)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Homo sapiens)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Bos taurus)
Autophosphorylation of KIT (Gallus gallus)
Autophosphorylation of KIT (Xenopus tropicalis)
Autophosphorylation of KIT (Danio rerio)
Autophosphorylation of KIT (Sus scrofa)
Autophosphorylation of KIT (Canis familiaris)
Autophosphorylation of KIT (Rattus norvegicus)
Autophosphorylation of KIT (Mus musculus)
Autophosphorylation of KIT (Homo sapiens)
Autophosphorylation of KIT (Bos taurus)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K produces PIP3 and other phosphatidyl inositides (Bos taurus)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Bos taurus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Bos taurus)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Bos taurus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Bos taurus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Bos taurus)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Bos taurus)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Homo sapiens)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Xenopus tropicalis)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Plasmodium falciparum)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Danio rerio)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Drosophila melanogaster)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Drosophila melanogaster)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Drosophila melanogaster)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Dictyostelium discoideum)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Dictyostelium discoideum)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Dictyostelium discoideum)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Dictyostelium discoideum)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Gallus gallus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Xenopus tropicalis)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Sus scrofa)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Sus scrofa)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Bos taurus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Canis familiaris)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Canis familiaris)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Canis familiaris)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the late endosome membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Dictyostelium discoideum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Caenorhabditis elegans)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Drosophila melanogaster)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Xenopus tropicalis)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Canis familiaris)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the late endosome membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the late endosome membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the Golgi membrane (Mus musculus)
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the Golgi membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by Pikfyve at the early endosome membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Plasmodium falciparum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Dictyostelium discoideum)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Dictyostelium discoideum)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Schizosaccharomyces pombe)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Caenorhabditis elegans)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Drosophila melanogaster)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Drosophila melanogaster)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Gallus gallus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Xenopus tropicalis)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Xenopus tropicalis)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Danio rerio)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Sus scrofa)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Sus scrofa)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Bos taurus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Bos taurus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Canis familiaris)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Canis familiaris)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Canis familiaris)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Mus musculus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4K2A/B at the early endosome membrane (Homo sapiens)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A at the early endosome membrane (Homo sapiens)
PI is phosphorylated to PI3P by PIK3C2A/3 at the early endosome membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,5)P2 by PIKFYVE at the early endosome membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Rattus norvegicus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Homo sapiens)
PI4P is phosphorylated to PI(3,4)P2 by PIK3C2A/G at the Golgi membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Mus musculus)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Mus musculus)
PI is phosphorylated to PI4P by PI4KB at the Golgi membrane (Homo sapiens)
PI is phosphorylated to PI3P by PIK3C2A/3 at the Golgi membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Xenopus tropicalis)
RBKS phosphorylates ribose to R5P (Saccharomyces cerevisiae)
RBKS phosphorylates ribose to R5P (Schizosaccharomyces pombe)
RBKS phosphorylates ribose to R5P (Dictyostelium discoideum)
RBKS phosphorylates ribose to R5P (Caenorhabditis elegans)
RBKS phosphorylates ribose to R5P (Drosophila melanogaster)
RBKS phosphorylates ribose to R5P (Gallus gallus)
RBKS phosphorylates ribose to R5P (Xenopus tropicalis)
RBKS phosphorylates ribose to R5P (Danio rerio)
RBKS phosphorylates ribose to R5P (Sus scrofa)
RBKS phosphorylates ribose to R5P (Bos taurus)
RBKS phosphorylates ribose to R5P (Canis familiaris)
RBKS phosphorylates ribose to R5P (Rattus norvegicus)
RBKS phosphorylates ribose to R5P (Mus musculus)
RBKS phosphorylates ribose to R5P (Homo sapiens)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Plasmodium falciparum)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Saccharomyces cerevisiae)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Schizosaccharomyces pombe)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Caenorhabditis elegans)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Dictyostelium discoideum)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Drosophila melanogaster)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Gallus gallus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Danio rerio)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Sus scrofa)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Bos taurus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Canis familiaris)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Rattus norvegicus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Dictyostelium discoideum)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Gallus gallus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Sus scrofa)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Bos taurus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Canis familiaris)
ABCC1 transports cytosolic RCbl to extracellular region (Saccharomyces cerevisiae)
ABCC1 transports cytosolic RCbl to extracellular region (Schizosaccharomyces pombe)
ABCC1 transports cytosolic RCbl to extracellular region (Dictyostelium discoideum)
ABCC1 transports cytosolic RCbl to extracellular region (Caenorhabditis elegans)
ABCC1 transports cytosolic RCbl to extracellular region (Drosophila melanogaster)
ABCC1 transports cytosolic RCbl to extracellular region (Gallus gallus)
ABCC1 transports cytosolic RCbl to extracellular region (Xenopus tropicalis)
ABCC1 transports cytosolic RCbl to extracellular region (Sus scrofa)
ABCC1 transports cytosolic RCbl to extracellular region (Bos taurus)
ABCC1 transports cytosolic RCbl to extracellular region (Canis familiaris)
ABCC1 transports cytosolic RCbl to extracellular region (Rattus norvegicus)
ABCC1 transports cytosolic RCbl to extracellular region (Mus musculus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Dictyostelium discoideum)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Gallus gallus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Sus scrofa)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Bos taurus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Canis familiaris)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Mus musculus)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (gut mucosal cells) (Homo sapiens)
ABCC1 transports cytosolic RCbl to extracellular region (Homo sapiens)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Homo sapiens)
ABCD4:LMBRD1 transports RCbl from lysosomal lumen to cytosol (Mus musculus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Mus musculus)
PGK complexes (PGK1,2) phosphorylate 3PG to form 1,3BPG (Homo sapiens)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Saccharomyces cerevisiae)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Schizosaccharomyces pombe)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Dictyostelium discoideum)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Caenorhabditis elegans)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Gallus gallus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Danio rerio)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Sus scrofa)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Bos taurus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Canis familiaris)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Rattus norvegicus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Mus musculus)
DAK dimer phosphorylates D-glyceraldehyde to form D-glyceraldehyde 3-phosphate (Homo sapiens)
KHK dimer phosphorylates Fru to Fru 1-P (Dictyostelium discoideum)
KHK dimer phosphorylates Fru to Fru 1-P (Drosophila melanogaster)
KHK dimer phosphorylates Fru to Fru 1-P (Gallus gallus)
KHK dimer phosphorylates Fru to Fru 1-P (Sus scrofa)
KHK dimer phosphorylates Fru to Fru 1-P (Bos taurus)
KHK dimer phosphorylates Fru to Fru 1-P (Rattus norvegicus)
KHK dimer phosphorylates Fru to Fru 1-P (Mus musculus)
KHK dimer phosphorylates Fru to Fru 1-P (Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Gallus gallus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Bos taurus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Mus musculus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP (Homo sapiens)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Plasmodium falciparum)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Saccharomyces cerevisiae)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Schizosaccharomyces pombe)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Caenorhabditis elegans)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Drosophila melanogaster)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Gallus gallus)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Xenopus tropicalis)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Danio rerio)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Sus scrofa)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Bos taurus)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Canis familiaris)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Rattus norvegicus)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Mus musculus)
HK1,2,3,GCK,HKDC1 phosphorylate Glc to form G6P (Homo sapiens)
XYLB phosphorylates D-xylulose (Saccharomyces cerevisiae)
XYLB phosphorylates D-xylulose (Schizosaccharomyces pombe)
XYLB phosphorylates D-xylulose (Caenorhabditis elegans)
XYLB phosphorylates D-xylulose (Drosophila melanogaster)
XYLB phosphorylates D-xylulose (Gallus gallus)
XYLB phosphorylates D-xylulose (Xenopus tropicalis)
XYLB phosphorylates D-xylulose (Danio rerio)
XYLB phosphorylates D-xylulose (Sus scrofa)
XYLB phosphorylates D-xylulose (Bos taurus)
XYLB phosphorylates D-xylulose (Canis familiaris)
XYLB phosphorylates D-xylulose (Rattus norvegicus)
XYLB phosphorylates D-xylulose (Mus musculus)
XYLB phosphorylates D-xylulose (Homo sapiens)
ETA is phosphorylated to PETA by CHK/ETNK (Plasmodium falciparum)
ETA is phosphorylated to PETA by CHK/ETNK (Saccharomyces cerevisiae)
ETA is phosphorylated to PETA by CHK/ETNK (Schizosaccharomyces pombe)
ETA is phosphorylated to PETA by CHK/ETNK (Dictyostelium discoideum)
ETA is phosphorylated to PETA by CHK/ETNK (Caenorhabditis elegans)
ETA is phosphorylated to PETA by CHK/ETNK (Drosophila melanogaster)
ETA is phosphorylated to PETA by CHK/ETNK (Gallus gallus)
ETA is phosphorylated to PETA by CHK/ETNK (Xenopus tropicalis)
ETA is phosphorylated to PETA by CHK/ETNK (Danio rerio)
ETA is phosphorylated to PETA by CHK/ETNK (Sus scrofa)
ETA is phosphorylated to PETA by CHK/ETNK (Bos taurus)
ETA is phosphorylated to PETA by CHK/ETNK (Canis familiaris)
ETA is phosphorylated to PETA by CHK/ETNK (Rattus norvegicus)
ETA is phosphorylated to PETA by CHK/ETNK (Mus musculus)
ETA is phosphorylated to PETA by CHK/ETNK (Homo sapiens)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Saccharomyces cerevisiae)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Schizosaccharomyces pombe)
Cho is phosphorylated to PCho by CHK dimer (Plasmodium falciparum)
Cho is phosphorylated to PCho by CHK dimer (Saccharomyces cerevisiae)
Cho is phosphorylated to PCho by CHK dimer (Schizosaccharomyces pombe)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Caenorhabditis elegans)
Cho is phosphorylated to PCho by CHK dimer (Caenorhabditis elegans)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Drosophila melanogaster)
Cho is phosphorylated to PCho by CHK dimer (Drosophila melanogaster)
Cho is phosphorylated to PCho by CHK dimer (Gallus gallus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Dictyostelium discoideum)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Gallus gallus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Danio rerio)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Sus scrofa)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Bos taurus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Rattus norvegicus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Mus musculus)
Cho is phosphorylated to PCho by CHK dimer (Xenopus tropicalis)
Cho is phosphorylated to PCho by CHK dimer (Danio rerio)
Cho is phosphorylated to PCho by CHK dimer (Sus scrofa)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Saccharomyces cerevisiae)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Dictyostelium discoideum)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Caenorhabditis elegans)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Drosophila melanogaster)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Gallus gallus)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Xenopus tropicalis)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Danio rerio)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Sus scrofa)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Bos taurus)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Canis familiaris)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Rattus norvegicus)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Mus musculus)
ABCD1-3 dimers transfer LCFAs from cytosol to peroxisomal matrix (Homo sapiens)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Canis familiaris)
Cho is phosphorylated to PCho by CHK dimer (Canis familiaris)
Cho is phosphorylated to PCho by CHK dimer (Bos taurus)
Conversion of Glycerol to Glycerol-3-phosphate (Plasmodium falciparum)
Conversion of Glycerol to Glycerol-3-phosphate (Saccharomyces cerevisiae)
Conversion of Glycerol to Glycerol-3-phosphate (Dictyostelium discoideum)
Conversion of Glycerol to Glycerol-3-phosphate (Caenorhabditis elegans)
Conversion of Glycerol to Glycerol-3-phosphate (Drosophila melanogaster)
Conversion of Glycerol to Glycerol-3-phosphate (Gallus gallus)
Conversion of Glycerol to Glycerol-3-phosphate (Xenopus tropicalis)
Conversion of Glycerol to Glycerol-3-phosphate (Sus scrofa)
Conversion of Glycerol to Glycerol-3-phosphate (Bos taurus)
Conversion of Glycerol to Glycerol-3-phosphate (Canis familiaris)
Conversion of Glycerol to Glycerol-3-phosphate (Mus musculus)
Conversion of Glycerol to Glycerol-3-phosphate (Homo sapiens)
Conversion of Glycerol to Glycerol-3-phosphate (Rattus norvegicus)
Cho is phosphorylated to PCho by CHK dimer (Rattus norvegicus)
Cho is phosphorylated to PCho by CHK dimer (Homo sapiens)
Cho is phosphorylated to PCho by CHK dimer (Mus musculus)
PI is phosphorylated to PI4P by PI4KA/2B at the ER membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4KA/2A/2B at the Golgi membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Homo sapiens)
PI is phosphorylated to PI4P by PI4K2A/B at the plasma membrane (Canis familiaris)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Canis familiaris)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Canis familiaris)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Canis familiaris)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Canis familiaris)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Rattus norvegicus)
PI is phosphorylated to PI5P by PIP5K1A/B at the plasma membrane (Mus musculus)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Mus musculus)
Activated FGFR4 phosphorylates PPTN11 (Drosophila melanogaster)
Activated FGFR4 phosphorylates PPTN11 (Gallus gallus)
Activated FGFR4 phosphorylates PPTN11 (Xenopus tropicalis)
Activated FGFR4 phosphorylates PPTN11 (Sus scrofa)
Activated FGFR4 phosphorylates PPTN11 (Bos taurus)
Activated FGFR4 phosphorylates PPTN11 (Canis familiaris)
Activated FGFR4 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR4 phosphorylates PPTN11 (Homo sapiens)
Activated FGFR4 phosphorylates FRS2 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR4 phosphorylates FRS2 (Gallus gallus)
Activated FGFR4 phosphorylates FRS2 (Xenopus tropicalis)
Activated FGFR4 phosphorylates FRS2 (Sus scrofa)
Activated FGFR4 phosphorylates FRS2 (Bos taurus)
Activated FGFR4 phosphorylates FRS2 (Canis familiaris)
Activated FGFR4 phosphorylates FRS2 (Rattus norvegicus)
Activated FGFR4 phosphorylates FRS2 (Homo sapiens)
Activated FGFR4 phosphorylates FRS2 (Mus musculus)
Activated FGFR4 phosphorylates FRS3 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates FRS3 (Drosophila melanogaster)
Activated FGFR4 phosphorylates FRS3 (Gallus gallus)
Activated FGFR4 phosphorylates FRS3 (Xenopus tropicalis)
Activated FGFR4 phosphorylates FRS3 (Danio rerio)
Activated FGFR4 phosphorylates FRS3 (Sus scrofa)
Activated FGFR4 phosphorylates FRS3 (Bos taurus)
Activated FGFR4 phosphorylates FRS3 (Canis familiaris)
Activated FGFR4 phosphorylates FRS3 (Rattus norvegicus)
Activated FGFR4 phosphorylates FRS3 (Homo sapiens)
Activated FGFR4 phosphorylates FRS3 (Mus musculus)
Activated FGFR4 phosphorylates PPTN11 (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
PI3K produces PIP3 and other phosphatidyl inositides (Mus musculus)
PI3K produces PIP3 and other phosphatidyl inositides (Homo sapiens)
PI3K produces PIP3 and other phosphatidyl inositides (Rattus norvegicus)
PI(4,5)P2 is phosphorylated to PI(3,4,5)P3 by PIK3C[1] at the plasma membrane (Rattus norvegicus)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Rattus norvegicus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Homo sapiens)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Homo sapiens)
PI3P is phosphorylated to PI(3,4)P2 by PIP4K2/5K1 at the plasma membrane (Mus musculus)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Mus musculus)
PI4P is phosphorylated to PI(3,4)P2 by PI3K3C[2] at the plasma membrane (Mus musculus)
PI(3,4)P2 is phosphorylated to PI(3,4,5)P3 by PIP5K1A-C at the plasma membrane (Mus musculus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Mus musculus)
PI3P is phosphorylated to PI(3,5)P2 by PIP5K1A/B at the plasma membrane (Homo sapiens)
PI5P is phosphorylated to PI(4,5)P2 by PIP4K2 dimers at the plasma membrane (Homo sapiens)
Src phosphorylates CD3 dimers in IgG:Lma antigens:FCGR3A:CD3 dimers (Homo sapiens)
Src phosphorylate SYK in IgG:Leishmania surface:p-FCGR3A:SYK (Homo sapiens)
Phosphorylation and activation of PLCG due to FCGR3A effect (Homo sapiens)
Phosphorylation of PLC-gamma1 (Drosophila melanogaster)
Phosphorylation of PLC-gamma1 (Gallus gallus)
Phosphorylation of PLC-gamma1 (Xenopus tropicalis)
Phosphorylation of PLC-gamma1 (Sus scrofa)
Phosphorylation of PLC-gamma1 (Bos taurus)
Phosphorylation of PLC-gamma1 (Canis familiaris)
Phosphorylation of PLC-gamma1 (Rattus norvegicus)
Phosphorylation of PLC-gamma1 (Mus musculus)
Phosphorylation of SLP-76 (Sus scrofa)
Phosphorylation of SLP-76 (Bos taurus)
Phosphorylation of SLP-76 (Canis familiaris)
Phosphorylation of SLP-76 (Rattus norvegicus)
Phosphorylation of SLP-76 (Mus musculus)
Phosphorylation of TBSMs in LAT (Sus scrofa)
Phosphorylation of TBSMs in LAT (Bos taurus)
Phosphorylation of TBSMs in LAT (Canis familiaris)
Phosphorylation of TBSMs in LAT (Rattus norvegicus)
Phosphorylation of TBSMs in LAT (Mus musculus)
Activation of ZAP-70 (Gallus gallus)
Activation of ZAP-70 (Sus scrofa)
Activation of ZAP-70 (Bos taurus)
Activation of ZAP-70 (Canis familiaris)
Activation of ZAP-70 (Rattus norvegicus)
Activation of ZAP-70 (Mus musculus)
Phosphorylation of ZAP-70 by Lck (Gallus gallus)
Phosphorylation of ZAP-70 by Lck (Sus scrofa)
Phosphorylation of ZAP-70 by Lck (Bos taurus)
Phosphorylation of ZAP-70 by Lck (Canis familiaris)
Phosphorylation of ZAP-70 by Lck (Rattus norvegicus)
Phosphorylation of ZAP-70 by Lck (Mus musculus)
Phosphorylation of ITAM motifs in CD3 complexes (Gallus gallus)
Phosphorylation of ITAM motifs in CD3 complexes (Sus scrofa)
Phosphorylation of ITAM motifs in CD3 complexes (Bos taurus)
Phosphorylation of ITAM motifs in CD3 complexes (Canis familiaris)
Phosphorylation of ITAM motifs in CD3 complexes (Rattus norvegicus)
Phosphorylation of ITAM motifs in CD3 complexes (Mus musculus)
Activation of Lck (Gallus gallus)
Activation of Lck (Sus scrofa)
Activation of Lck (Bos taurus)
Activation of Lck (Canis familiaris)
Activation of Lck (Rattus norvegicus)
Activation of Lck (Mus musculus)
Inactivation of Lck by Csk (Gallus gallus)
Inactivation of Lck by Csk (Sus scrofa)
Inactivation of Lck by Csk (Bos taurus)
Inactivation of Lck by Csk (Canis familiaris)
Inactivation of Lck by Csk (Rattus norvegicus)
Inactivation of Lck by Csk (Mus musculus)
Inactivation of Lck by Csk (Homo sapiens)
Activation of Lck (Homo sapiens)
Phosphorylation of ITAM motifs in CD3 complexes (Homo sapiens)
Phosphorylation of ZAP-70 by Lck (Homo sapiens)
Activation of ZAP-70 (Homo sapiens)
Phosphorylation of TBSMs in LAT (Homo sapiens)
Phosphorylation of SLP-76 (Homo sapiens)
Phosphorylation of PLC-gamma1 (Homo sapiens)
Activated FGFR4 phosphorylates PLCG1 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates PLCG1 (Drosophila melanogaster)
Activated FGFR4 phosphorylates PLCG1 (Gallus gallus)
Activated FGFR4 phosphorylates PLCG1 (Xenopus tropicalis)
Activated FGFR4 phosphorylates PLCG1 (Danio rerio)
Activated FGFR4 phosphorylates PLCG1 (Sus scrofa)
Activated FGFR4 phosphorylates PLCG1 (Bos taurus)
Activated FGFR4 phosphorylates PLCG1 (Canis familiaris)
Activated FGFR4 phosphorylates PLCG1 (Rattus norvegicus)
Activated FGFR4 phosphorylates PLCG1 (Mus musculus)
Activated FGFR4 phosphorylates PLCG1 (Homo sapiens)
Activated FGFR2 phosphorylates PLCG1 (Drosophila melanogaster)
Activated FGFR2 phosphorylates PLCG1 (Gallus gallus)
Activated FGFR2 phosphorylates PLCG1 (Danio rerio)
Activated FGFR2 phosphorylates PLCG1 (Bos taurus)
Activated FGFR2 phosphorylates PLCG1 (Canis familiaris)
Activated FGFR2 phosphorylates PLCG1 (Rattus norvegicus)
Activated FGFR2 phosphorylates PLCG1 (Mus musculus)
Activated FGFR2 phosphorylates PLCG1 (Homo sapiens)
EGFR activates PLC-gamma1 by phosphorylation (Drosophila melanogaster)
EGFR activates PLC-gamma1 by phosphorylation (Gallus gallus)
EGFR activates PLC-gamma1 by phosphorylation (Xenopus tropicalis)
EGFR activates PLC-gamma1 by phosphorylation (Danio rerio)
EGFR activates PLC-gamma1 by phosphorylation (Sus scrofa)
EGFR activates PLC-gamma1 by phosphorylation (Bos taurus)
EGFR activates PLC-gamma1 by phosphorylation (Canis familiaris)
EGFR activates PLC-gamma1 by phosphorylation (Rattus norvegicus)
EGFR activates PLC-gamma1 by phosphorylation (Mus musculus)
Phosphorylation of EGFR by SRC kinase (Caenorhabditis elegans)
Phosphorylation of EGFR by SRC kinase (Drosophila melanogaster)
Phosphorylation of EGFR by SRC kinase (Gallus gallus)
Phosphorylation of EGFR by SRC kinase (Danio rerio)
Phosphorylation of EGFR by SRC kinase (Sus scrofa)
Phosphorylation of EGFR by SRC kinase (Bos taurus)
Phosphorylation of EGFR by SRC kinase (Canis familiaris)
Phosphorylation of EGFR by SRC kinase (Rattus norvegicus)
Phosphorylation of EGFR by SRC kinase (Mus musculus)
Phosphorylation of EGFR by SRC kinase (Homo sapiens)
EGFR activates PLC-gamma1 by phosphorylation (Homo sapiens)
SFKs phosphorylate PLCG1 (Gallus gallus)
SFKs phosphorylate PLCG1 (Danio rerio)
SFKs phosphorylate PLCG1 (Sus scrofa)
SFKs phosphorylate PLCG1 (Bos taurus)
SFKs phosphorylate PLCG1 (Canis familiaris)
SFKs phosphorylate PLCG1 (Rattus norvegicus)
SFKs phosphorylate PLCG1 (Mus musculus)
VEGFR2 autophosphorylates (Gallus gallus)
VEGFR2 autophosphorylates (Xenopus tropicalis)
VEGFR2 autophosphorylates (Danio rerio)
VEGFR2 autophosphorylates (Sus scrofa)
VEGFR2 autophosphorylates (Bos taurus)
VEGFR2 autophosphorylates (Canis familiaris)
VEGFR2 autophosphorylates (Rattus norvegicus)
VEGFR2 autophosphorylates (Mus musculus)
VEGFR2 autophosphorylates (Homo sapiens)
SFKs phosphorylate PLCG1 (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Gallus gallus)
PI3K phosphorylates PIP2 to PIP3 (Sus scrofa)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Canis familiaris)
PI3K phosphorylates PIP2 to PIP3 (Rattus norvegicus)
PI3K phosphorylates PIP2 to PIP3 (Mus musculus)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
Phosphorylation and activation of PLCG (Gallus gallus)
Phosphorylation and activation of PLCG (Sus scrofa)
Phosphorylation and activation of PLCG (Bos taurus)
Phosphorylation and activation of PLCG (Canis familiaris)
Phosphorylation and activation of PLCG (Rattus norvegicus)
Phosphorylation and activation of PLCG (Mus musculus)
Phosphorylation and activation of PLCG (Homo sapiens)
Active Trk phosphorylates Plcg1 (Rattus norvegicus)
Trk receptor autophosphorylates (Rattus norvegicus)
TrkA receptor autophosphorylates (Homo sapiens)
TrkA phosphorylates PLCG1 (Homo sapiens)
Activated FGFR1 phosphorylates PLCG1 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates PLCG1 (Drosophila melanogaster)
Activated FGFR1 phosphorylates PLCG1 (Gallus gallus)
Activated FGFR1 phosphorylates PLCG1 (Xenopus tropicalis)
Activated FGFR1 phosphorylates PLCG1 (Danio rerio)
Activated FGFR1 phosphorylates PLCG1 (Sus scrofa)
Activated FGFR1 phosphorylates PLCG1 (Bos taurus)
Activated FGFR1 phosphorylates PLCG1 (Canis familiaris)
Activated FGFR1 phosphorylates PLCG1 (Rattus norvegicus)
Activated FGFR1 phosphorylates PLCG1 (Mus musculus)
Activated FGFR1 phosphorylates PLCG1 (Homo sapiens)
Activated FGFR3 phosphorylates PLCG1 (Drosophila melanogaster)
Activated FGFR3 phosphorylates PLCG1 (Gallus gallus)
Activated FGFR3 phosphorylates PLCG1 (Danio rerio)
Activated FGFR3 phosphorylates PLCG1 (Bos taurus)
Activated FGFR3 phosphorylates PLCG1 (Canis familiaris)
Activated FGFR3 phosphorylates PLCG1 (Rattus norvegicus)
Activated FGFR3 phosphorylates PLCG1 (Mus musculus)
Activated FGFR3 phosphorylates PLCG1 (Homo sapiens)
Syk activation leads to SLP-76 activation (Drosophila melanogaster)
Syk activation leads to SLP-76 activation (Gallus gallus)
Syk activation leads to SLP-76 activation (Xenopus tropicalis)
Syk activation leads to SLP-76 activation (Sus scrofa)
Syk activation leads to SLP-76 activation (Bos taurus)
Syk activation leads to SLP-76 activation (Canis familiaris)
Syk activation leads to SLP-76 activation (Rattus norvegicus)
Syk activation leads to SLP-76 activation (Mus musculus)
SYK autophosphorylates (Xenopus tropicalis)
SYK autophosphorylates (Sus scrofa)
SYK autophosphorylates (Bos taurus)
SYK autophosphorylates (Canis familiaris)
SYK autophosphorylates (Rattus norvegicus)
SYK autophosphorylates (Mus musculus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Xenopus tropicalis)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Sus scrofa)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Bos taurus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Canis familiaris)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Rattus norvegicus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Mus musculus)
Fyn/Lyn-mediated phosphorylation of FcR1 gamma (Homo sapiens)
SYK autophosphorylates (Homo sapiens)
Syk activation leads to SLP-76 activation (Homo sapiens)
Autophosphorylation of PDGF alpha receptors (Caenorhabditis elegans)
Autophosphorylation of PDGF alpha receptors (Drosophila melanogaster)
Autophosphorylation of PDGF alpha receptors (Gallus gallus)
Autophosphorylation of PDGF alpha receptors (Danio rerio)
Autophosphorylation of PDGF alpha receptors (Sus scrofa)
Autophosphorylation of PDGF alpha receptors (Bos taurus)
Autophosphorylation of PDGF alpha receptors (Canis familiaris)
Autophosphorylation of PDGF alpha receptors (Rattus norvegicus)
Autophosphorylation of PDGF alpha receptors (Mus musculus)
Autophosphorylation of PDGF alpha receptors (Homo sapiens)
Autophosphorylation of PDGF alpha/beta receptors (Caenorhabditis elegans)
Autophosphorylation of PDGF alpha/beta receptors (Drosophila melanogaster)
Autophosphorylation of PDGF alpha/beta receptors (Gallus gallus)
Autophosphorylation of PDGF alpha/beta receptors (Xenopus tropicalis)
Autophosphorylation of PDGF alpha/beta receptors (Danio rerio)
Autophosphorylation of PDGF alpha/beta receptors (Sus scrofa)
Autophosphorylation of PDGF alpha/beta receptors (Bos taurus)
Autophosphorylation of PDGF alpha/beta receptors (Canis familiaris)
Autophosphorylation of PDGF alpha/beta receptors (Rattus norvegicus)
Autophosphorylation of PDGF alpha/beta receptors (Mus musculus)
Autophosphorylation of PDGF alpha/beta receptors (Homo sapiens)
Autophosphorylation of PDGF beta receptors (Caenorhabditis elegans)
Autophosphorylation of PDGF beta receptors (Drosophila melanogaster)
Autophosphorylation of PDGF beta receptors (Gallus gallus)
Autophosphorylation of PDGF beta receptors (Xenopus tropicalis)
Autophosphorylation of PDGF beta receptors (Sus scrofa)
Autophosphorylation of PDGF beta receptors (Bos taurus)
Autophosphorylation of PDGF beta receptors (Canis familiaris)
Autophosphorylation of PDGF beta receptors (Rattus norvegicus)
Autophosphorylation of PDGF beta receptors (Mus musculus)
Autophosphorylation of PDGF beta receptors (Homo sapiens)
Activated FGFR4 phosphorylates SHC1 (Caenorhabditis elegans)
Activated FGFR4 phosphorylates SHC1 (Drosophila melanogaster)
Activated FGFR4 phosphorylates SHC1 (Gallus gallus)
Activated FGFR4 phosphorylates SHC1 (Xenopus tropicalis)
Activated FGFR4 phosphorylates SHC1 (Sus scrofa)
Activated FGFR4 phosphorylates SHC1 (Bos taurus)
Activated FGFR4 phosphorylates SHC1 (Canis familiaris)
Activated FGFR4 phosphorylates SHC1 (Rattus norvegicus)
Activated FGFR4 phosphorylates SHC1 (Mus musculus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Caenorhabditis elegans)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Drosophila melanogaster)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Gallus gallus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Xenopus tropicalis)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Sus scrofa)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Bos taurus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Canis familiaris)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Rattus norvegicus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Mus musculus)
Autocatalytic phosphorylation of BetaKlotho-bound FGFR4 (Homo sapiens)
Autocatalytic phosphorylation of FGFR4 (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR4 (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR4 (Gallus gallus)
Autocatalytic phosphorylation of FGFR4 (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR4 (Danio rerio)
Autocatalytic phosphorylation of FGFR4 (Sus scrofa)
Autocatalytic phosphorylation of FGFR4 (Bos taurus)
Autocatalytic phosphorylation of FGFR4 (Canis familiaris)
Autocatalytic phosphorylation of FGFR4 (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR4 (Mus musculus)
Autocatalytic phosphorylation of FGFR4 (Homo sapiens)
Activated FGFR4 phosphorylates SHC1 (Homo sapiens)
Activated FGFR2 phosphorylates FRS3 (Drosophila melanogaster)
Activated FGFR2 phosphorylates FRS3 (Gallus gallus)
Activated FGFR2 phosphorylates FRS3 (Danio rerio)
Activated FGFR2 phosphorylates FRS3 (Bos taurus)
Activated FGFR2 phosphorylates FRS3 (Canis familiaris)
Activated FGFR2 phosphorylates FRS3 (Rattus norvegicus)
Activated FGFR2 phosphorylates FRS3 (Mus musculus)
Activated FGFR2 phosphorylates FRS3 (Homo sapiens)
Phosphorylation of RAF (Homo sapiens)
RAF phosphorylates MAP2K dimer (Homo sapiens)
MAP2Ks phosphorylate MAPKs (Homo sapiens)
PI4P is phosphorylated to PI(4,5)P2 by PIP5K1A-C at the plasma membrane (Homo sapiens)
Activated FGFR1 phosphorylates FRS2 (Caenorhabditis elegans)
Activated FGFR1 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR1 phosphorylates FRS2 (Gallus gallus)
Activated FGFR1 phosphorylates FRS2 (Xenopus tropicalis)
Activated FGFR1 phosphorylates FRS2 (Danio rerio)
Activated FGFR1 phosphorylates FRS2 (Sus scrofa)
Activated FGFR1 phosphorylates FRS2 (Bos taurus)
Activated FGFR1 phosphorylates FRS2 (Canis familiaris)
Activated FGFR1 phosphorylates FRS2 (Rattus norvegicus)
Activated FGFR1 phosphorylates FRS2 (Mus musculus)
Autocatalytic phosphorylation of FGFR1c (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR1c (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR1c (Gallus gallus)
Autocatalytic phosphorylation of FGFR1c (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR1c (Danio rerio)
Autocatalytic phosphorylation of FGFR1c (Sus scrofa)
Autocatalytic phosphorylation of FGFR1c (Bos taurus)
Autocatalytic phosphorylation of FGFR1c (Canis familiaris)
Autocatalytic phosphorylation of FGFR1c (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR1c (Mus musculus)
Autocatalytic phosphorylation of FGFR1c (Homo sapiens)
Autocatalytic phosphorylation of FGFR1b (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR1b (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR1b (Gallus gallus)
Autocatalytic phosphorylation of FGFR1b (Xenopus tropicalis)
Autocatalytic phosphorylation of FGFR1b (Danio rerio)
Autocatalytic phosphorylation of FGFR1b (Sus scrofa)
Autocatalytic phosphorylation of FGFR1b (Bos taurus)
Autocatalytic phosphorylation of FGFR1b (Canis familiaris)
Autocatalytic phosphorylation of FGFR1b (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR1b (Mus musculus)
Autocatalytic phosphorylation of FGFR1b (Homo sapiens)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Caenorhabditis elegans)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Drosophila melanogaster)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Gallus gallus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Xenopus tropicalis)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Danio rerio)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Sus scrofa)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Bos taurus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Canis familiaris)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Rattus norvegicus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Mus musculus)
Autocatalytic phosphorylation of Klotho-bound FGFR1c (Homo sapiens)
Activated FGFR1 phosphorylates FRS2 (Homo sapiens)
NTRK1 phosphorylates IRS (Mus musculus)
TRKA phosphorylates IRS (Homo sapiens)
Trans-autophosphorylation of ERBB2 heterodimers (Caenorhabditis elegans)
Trans-autophosphorylation of ERBB2 heterodimers (Drosophila melanogaster)
Trans-autophosphorylation of ERBB2 heterodimers (Gallus gallus)
Trans-autophosphorylation of ERBB2 heterodimers (Danio rerio)
Trans-autophosphorylation of ERBB2 heterodimers (Sus scrofa)
Trans-autophosphorylation of ERBB2 heterodimers (Bos taurus)
Trans-autophosphorylation of ERBB2 heterodimers (Canis familiaris)
Trans-autophosphorylation of ERBB2 heterodimers (Rattus norvegicus)
Trans-autophosphorylation of ERBB2 heterodimers (Mus musculus)
Trans-autophosphorylation of ERBB2 heterodimers (Homo sapiens)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Caenorhabditis elegans)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Drosophila melanogaster)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Gallus gallus)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Danio rerio)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Sus scrofa)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Bos taurus)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Canis familiaris)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Rattus norvegicus)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Mus musculus)
SRC family kinases phosphorylate ERBB2 (Caenorhabditis elegans)
SRC family kinases phosphorylate ERBB2 (Drosophila melanogaster)
SRC family kinases phosphorylate ERBB2 (Gallus gallus)
SRC family kinases phosphorylate ERBB2 (Danio rerio)
SRC family kinases phosphorylate ERBB2 (Sus scrofa)
SRC family kinases phosphorylate ERBB2 (Bos taurus)
SRC family kinases phosphorylate ERBB2 (Canis familiaris)
SRC family kinases phosphorylate ERBB2 (Rattus norvegicus)
SRC family kinases phosphorylate ERBB2 (Mus musculus)
SRC family kinases phosphorylate ERBB2 (Homo sapiens)
Trans-autophosphorylation of p-Y877-ERBB2 heterodimers (Homo sapiens)
Activated FGFR3 phosphorylates PPTN11 (Drosophila melanogaster)
Activated FGFR3 phosphorylates PPTN11 (Gallus gallus)
Activated FGFR3 phosphorylates PPTN11 (Xenopus tropicalis)
Activated FGFR3 phosphorylates PPTN11 (Danio rerio)
Activated FGFR3 phosphorylates PPTN11 (Sus scrofa)
Activated FGFR3 phosphorylates PPTN11 (Bos taurus)
Activated FGFR3 phosphorylates PPTN11 (Canis familiaris)
Activated FGFR3 phosphorylates PPTN11 (Rattus norvegicus)
Activated FGFR3 phosphorylates PPTN11 (Mus musculus)
Activated FGFR3 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR3 phosphorylates FRS2 (Gallus gallus)
Activated FGFR3 phosphorylates FRS2 (Bos taurus)
Activated FGFR3 phosphorylates FRS2 (Canis familiaris)
Activated FGFR3 phosphorylates FRS2 (Rattus norvegicus)
Activated FGFR3 phosphorylates FRS2 (Mus musculus)
Activated FGFR3 phosphorylates FRS2 (Homo sapiens)
Activated FGFR3 phosphorylates FRS3 (Drosophila melanogaster)
Activated FGFR3 phosphorylates FRS3 (Gallus gallus)
Activated FGFR3 phosphorylates FRS3 (Danio rerio)
Activated FGFR3 phosphorylates FRS3 (Bos taurus)
Activated FGFR3 phosphorylates FRS3 (Canis familiaris)
Activated FGFR3 phosphorylates FRS3 (Rattus norvegicus)
Activated FGFR3 phosphorylates FRS3 (Mus musculus)
Autocatalytic phosphorylation of FGFR3c (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR3c (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR3c (Gallus gallus)
Autocatalytic phosphorylation of FGFR3c (Danio rerio)
Autocatalytic phosphorylation of FGFR3c (Bos taurus)
Autocatalytic phosphorylation of FGFR3c (Canis familiaris)
Autocatalytic phosphorylation of FGFR3c (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR3c (Mus musculus)
Autocatalytic phosphorylation of FGFR3c (Homo sapiens)
Autocatalytic phosphorylation of FGFR3b (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR3b (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR3b (Gallus gallus)
Autocatalytic phosphorylation of FGFR3b (Danio rerio)
Autocatalytic phosphorylation of FGFR3b (Bos taurus)
Autocatalytic phosphorylation of FGFR3b (Canis familiaris)
Autocatalytic phosphorylation of FGFR3b (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR3b (Mus musculus)
Autocatalytic phosphorylation of FGFR3b (Homo sapiens)
Activated FGFR3 phosphorylates FRS3 (Homo sapiens)
Activated FGFR3 phosphorylates PPTN11 (Homo sapiens)
GAB1 phosphorylation by EGFR kinase (Drosophila melanogaster)
GAB1 phosphorylation by EGFR kinase (Caenorhabditis elegans)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Caenorhabditis elegans)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Drosophila melanogaster)
GAB1 phosphorylation by EGFR kinase (Gallus gallus)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Gallus gallus)
GAB1 phosphorylation by EGFR kinase (Xenopus tropicalis)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Xenopus tropicalis)
GAB1 phosphorylation by EGFR kinase (Danio rerio)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Danio rerio)
GAB1 phosphorylation by EGFR kinase (Sus scrofa)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Sus scrofa)
GAB1 phosphorylation by EGFR kinase (Bos taurus)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Bos taurus)
GAB1 phosphorylation by EGFR kinase (Canis familiaris)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Canis familiaris)
GAB1 phosphorylation by EGFR kinase (Rattus norvegicus)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Rattus norvegicus)
EGFR autophosphorylation (Caenorhabditis elegans)
EGFR autophosphorylation (Drosophila melanogaster)
EGFR autophosphorylation (Gallus gallus)
EGFR autophosphorylation (Xenopus tropicalis)
EGFR autophosphorylation (Danio rerio)
EGFR autophosphorylation (Sus scrofa)
EGFR autophosphorylation (Bos taurus)
EGFR autophosphorylation (Canis familiaris)
EGFR autophosphorylation (Rattus norvegicus)
EGFR autophosphorylation (Homo sapiens)
EGFR autophosphorylation (Mus musculus)
GAB1 phosphorylation by EGFR kinase (Mus musculus)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Mus musculus)
PI3K converts phosphatidylinositol-4,5-bisphosphate (PIP2) to phosphatidylinositol-3,4,5-trisphosphate (PIP3) (Homo sapiens)
GAB1 phosphorylation by EGFR kinase (Homo sapiens)
Trans-autophosphorylation of ERBB4 homodimers (Drosophila melanogaster)
Trans-autophosphorylation of ERBB4 homodimers (Gallus gallus)
Trans-autophosphorylation of ERBB4 homodimers (Xenopus tropicalis)
Trans-autophosphorylation of ERBB4 homodimers (Danio rerio)
Trans-autophosphorylation of ERBB4 homodimers (Sus scrofa)
Trans-autophosphorylation of ERBB4 homodimers (Bos taurus)
Trans-autophosphorylation of ERBB4 homodimers (Canis familiaris)
Trans-autophosphorylation of ERBB4 homodimers (Rattus norvegicus)
Trans-autophosphorylation of ERBB4 homodimers (Mus musculus)
Trans-autophosphorylation of ERBB4 homodimers (Homo sapiens)
Activated FGFR2 phosphorylates FRS2 (Drosophila melanogaster)
Activated FGFR2 phosphorylates FRS2 (Gallus gallus)
Activated FGFR2 phosphorylates FRS2 (Bos taurus)
Activated FGFR2 phosphorylates FRS2 (Canis familiaris)
Activated FGFR2 phosphorylates FRS2 (Rattus norvegicus)
Activated FGFR2 phosphorylates FRS2 (Mus musculus)
Autocatalytic phosphorylation of FGFR2c (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR2c (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR2c (Gallus gallus)
Autocatalytic phosphorylation of FGFR2c (Danio rerio)
Autocatalytic phosphorylation of FGFR2c (Bos taurus)
Autocatalytic phosphorylation of FGFR2c (Canis familiaris)
Autocatalytic phosphorylation of FGFR2c (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR2c (Mus musculus)
Autocatalytic phosphorylation of FGFR2c (Homo sapiens)
Autocatalytic phosphorylation of FGFR2b (Caenorhabditis elegans)
Autocatalytic phosphorylation of FGFR2b (Drosophila melanogaster)
Autocatalytic phosphorylation of FGFR2b (Gallus gallus)
Autocatalytic phosphorylation of FGFR2b (Danio rerio)
Autocatalytic phosphorylation of FGFR2b (Bos taurus)
Autocatalytic phosphorylation of FGFR2b (Canis familiaris)
Autocatalytic phosphorylation of FGFR2b (Rattus norvegicus)
Autocatalytic phosphorylation of FGFR2b (Mus musculus)
Autocatalytic phosphorylation of FGFR2b (Homo sapiens)
Activated FGFR2 phosphorylates FRS2 (Homo sapiens)
PI3K phosphorylates PIP2 to PIP3 (Homo sapiens)
TORC2 (mTOR) phosphorylates AKT at S473 (Homo sapiens)
PDPK1 phosphorylates AKT at T308 (Homo sapiens)
Phosphorylation of Cyclin B1 in the CRS domain (Caenorhabditis elegans)
Phosphorylation of Cyclin B1 in the CRS domain (Drosophila melanogaster)
Phosphorylation of Cyclin B1 in the CRS domain (Danio rerio)
PLK1 phosphorylates BORA (Caenorhabditis elegans)
CDK1 phosphorylates BORA (Caenorhabditis elegans)
CDK1 phosphorylates BORA (Drosophila melanogaster)
CDK1 phosphorylates BORA (Danio rerio)
Phosphorylation of Cyclin B1 in the CRS domain (Xenopus tropicalis)
Phosphorylation of Cyclin B1 in the CRS domain (Sus scrofa)
Phosphorylation of Cyclin B1 in the CRS domain (Bos taurus)
Phosphorylation of Cyclin B1 in the CRS domain (Canis familiaris)
Phosphorylation of Cyclin B1 in the CRS domain (Rattus norvegicus)
Phosphorylation of Cyclin B1 in the CRS domain (Mus musculus)
Myt-1 mediated phosphorylation of Cyclin A:Cdc2 (Homo sapiens)
PLK1 phosphorylates BORA (Drosophila melanogaster)
CDK1 phosphorylates BORA (Gallus gallus)
AURKA phosphorylates PLK1 (Gallus gallus)
PLK1 phosphorylates BORA (Gallus gallus)
CDK1 phosphorylates BORA (Xenopus tropicalis)
AURKA phosphorylates PLK1 (Xenopus tropicalis)
PLK1 phosphorylates BORA (Xenopus tropicalis)
PLK1 phosphorylates BORA (Danio rerio)
CDK1 phosphorylates BORA (Sus scrofa)
AURKA phosphorylates PLK1 (Sus scrofa)
PLK1 phosphorylates BORA (Sus scrofa)
CDK1 phosphorylates BORA (Bos taurus)
AURKA phosphorylates PLK1 (Bos taurus)
PLK1 phosphorylates BORA (Bos taurus)
CDK1 phosphorylates BORA (Canis familiaris)
AURKA phosphorylates PLK1 (Canis familiaris)
PLK1 phosphorylates BORA (Canis familiaris)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Caenorhabditis elegans)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Drosophila melanogaster)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Danio rerio)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Sus scrofa)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Bos taurus)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Canis familiaris)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Homo sapiens)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Rattus norvegicus)
CDK1 phosphorylates BORA (Rattus norvegicus)
AURKA phosphorylates PLK1 (Rattus norvegicus)
PLK1 phosphorylates BORA (Rattus norvegicus)
AJUBA facilitates AURKA autophosphorylation (Gallus gallus)
AJUBA facilitates AURKA autophosphorylation (Xenopus tropicalis)
AJUBA facilitates AURKA autophosphorylation (Sus scrofa)
AJUBA facilitates AURKA autophosphorylation (Bos taurus)
AJUBA facilitates AURKA autophosphorylation (Canis familiaris)
AJUBA facilitates AURKA autophosphorylation (Rattus norvegicus)
AJUBA facilitates AURKA autophosphorylation (Homo sapiens)
AJUBA facilitates AURKA autophosphorylation (Mus musculus)
AURKA phosphorylates PLK1 (Mus musculus)
PLK1 phosphorylates BORA (Mus musculus)
PLK1 phosphorylates GTSE1 (Gallus gallus)
PLK1 phosphorylates GTSE1 (Xenopus tropicalis)
PLK1 phosphorylates GTSE1 (Danio rerio)
PLK1 phosphorylates GTSE1 (Sus scrofa)
PLK1 phosphorylates GTSE1 (Bos taurus)
PLK1 phosphorylates GTSE1 (Canis familiaris)
PLK1 phosphorylates GTSE1 (Rattus norvegicus)
PLK1 phosphorylates GTSE1 (Mus musculus)
PLK1 phosphorylates GTSE1 (Homo sapiens)
Activation of Cdc25C (Saccharomyces cerevisiae)
Activation of Cdc25C (Schizosaccharomyces pombe)
Activation of Cdc25C (Dictyostelium discoideum)
Activation of Cdc25C (Caenorhabditis elegans)
Activation of Cdc25C (Drosophila melanogaster)
Activation of Cdc25C (Sus scrofa)
Activation of Cdc25C (Bos taurus)
Activation of Cdc25C (Canis familiaris)
Activation of Cdc25C (Rattus norvegicus)
Activation of Cdc25C (Mus musculus)
Activation of Cdc25C (Homo sapiens)
Myt-1 mediated phosphorylation of Cyclin B:Cdc2 complexes (Mus musculus)
CDK1 phosphorylates BORA (Mus musculus)
CDK1 phosphorylates BORA (Homo sapiens)
AURKA phosphorylates PLK1 (Homo sapiens)
PLK1 phosphorylates BORA (Homo sapiens)
Phosphorylation of Cyclin B1 in the CRS domain (Homo sapiens)
Beclin-1 complex phosphorylates PtdIns (Saccharomyces cerevisiae)
Beclin-1 complex phosphorylates PtdIns (Schizosaccharomyces pombe)
Beclin-1 complex phosphorylates PtdIns (Dictyostelium discoideum)
Beclin-1 complex phosphorylates PtdIns (Caenorhabditis elegans)
Beclin-1 complex phosphorylates PtdIns (Drosophila melanogaster)
Beclin-1 complex phosphorylates PtdIns (Gallus gallus)
Beclin-1 complex phosphorylates PtdIns (Xenopus tropicalis)
Beclin-1 complex phosphorylates PtdIns (Sus scrofa)
Beclin-1 complex phosphorylates PtdIns (Bos taurus)
Beclin-1 complex phosphorylates PtdIns (Canis familiaris)
Beclin-1 complex phosphorylates PtdIns (Rattus norvegicus)
Beclin-1 complex phosphorylates PtdIns (Mus musculus)
Beclin-1 complex phosphorylates PtdIns (Homo sapiens)
p-AMPK phosphorylates TSC1:TSC2 (Schizosaccharomyces pombe)
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
p-AMPK phosphorylates TSC1:TSC2 (Canis familiaris)
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
p-AMPK phosphorylates TSC1:TSC2 (Homo sapiens)
ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)
ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)
ULK1 phosphorylates Beclin-1 (Dictyostelium discoideum)
ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)
ULK1 phosphorylates Beclin-1 (Drosophila melanogaster)
ULK1 phosphorylates Beclin-1 (Gallus gallus)
ULK1 phosphorylates Beclin-1 (Xenopus tropicalis)
ULK1 phosphorylates Beclin-1 (Sus scrofa)
ULK1 phosphorylates Beclin-1 (Bos taurus)
ULK1 phosphorylates Beclin-1 (Canis familiaris)
ULK1 phosphorylates Beclin-1 (Rattus norvegicus)
ULK1 phosphorylates Beclin-1 (Homo sapiens)
ULK1 phosphorylates Beclin-1 (Mus musculus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Schizosaccharomyces pombe)
ULK1 phosphorylates AMBRA1:BECN1 complex (Caenorhabditis elegans)
ULK1 phosphorylates AMBRA1:BECN1 complex (Drosophila melanogaster)
ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Xenopus tropicalis)
ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)
ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Canis familiaris)
ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)
ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)
ULK1 phosphorylates ATG13 and RB1CC1 (Saccharomyces cerevisiae)
ULK1 phosphorylates ATG13 and RB1CC1 (Schizosaccharomyces pombe)
ULK1 phosphorylates ATG13 and RB1CC1 (Dictyostelium discoideum)
ULK1 phosphorylates ATG13 and RB1CC1 (Caenorhabditis elegans)
ULK1 phosphorylates ATG13 and RB1CC1 (Drosophila melanogaster)
ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)
ULK1 phosphorylates ATG13 and RB1CC1 (Xenopus tropicalis)
ULK1 phosphorylates ATG13 and RB1CC1 (Sus scrofa)
ULK1 phosphorylates ATG13 and RB1CC1 (Bos taurus)
ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)
ULK1 phosphorylates ATG13 and RB1CC1 (Rattus norvegicus)
ULK1 phosphorylates ATG13 and RB1CC1 (Mus musculus)
Thr-180 of ULK1 is phosphorylated (Saccharomyces cerevisiae)
Thr-180 of ULK1 is phosphorylated (Schizosaccharomyces pombe)
Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)
Thr-180 of ULK1 is phosphorylated (Caenorhabditis elegans)
Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)
Thr-180 of ULK1 is phosphorylated (Gallus gallus)
Thr-180 of ULK1 is phosphorylated (Xenopus tropicalis)
Thr-180 of ULK1 is phosphorylated (Sus scrofa)
Thr-180 of ULK1 is phosphorylated (Bos taurus)
Thr-180 of ULK1 is phosphorylated (Canis familiaris)
Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)
Thr-180 of ULK1 is phosphorylated (Mus musculus)
AMPK (complex) phosphorylates ULK1 (complex) (Saccharomyces cerevisiae)
AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)
AMPK (complex) phosphorylates ULK1 (complex) (Dictyostelium discoideum)
AMPK (complex) phosphorylates ULK1 (complex) (Caenorhabditis elegans)
AMPK (complex) phosphorylates ULK1 (complex) (Drosophila melanogaster)
AMPK (complex) phosphorylates ULK1 (complex) (Gallus gallus)
AMPK (complex) phosphorylates ULK1 (complex) (Xenopus tropicalis)
AMPK (complex) phosphorylates ULK1 (complex) (Sus scrofa)
AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)
AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)
AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)
AMPK (complex) phosphorylates ULK1 (complex) (Mus musculus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Danio rerio)
Active MTORC1 phosphorylates ULK1 (Xenopus tropicalis)
Active MTORC1 phosphorylates ULK1 (Danio rerio)
Active MTORC1 phosphorylates ULK1 (Dictyostelium discoideum)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
Active MTORC1 phosphorylates ULK1 (Caenorhabditis elegans)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
Active MTORC1 phosphorylates ULK1 (Drosophila melanogaster)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
Active MTORC1 phosphorylates ULK1 (Gallus gallus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)
Active MTORC1 phosphorylates ULK1 (Sus scrofa)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)
Active MTORC1 phosphorylates ULK1 (Bos taurus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
Active MTORC1 phosphorylates ULK1 (Canis familiaris)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
Active MTORC1 phosphorylates ULK1 (Rattus norvegicus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
Active MTORC1 phosphorylates ULK1 (Mus musculus)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)
Active MTORC1 phosphorylates ULK1 (Homo sapiens)
Activation of cytosolic AMPK by phosphorylation (Gallus gallus)
PRKAA2 phosphorylates PLINs (Homo sapiens)
FUNDC1 is phosphorylated by CK2 (Homo sapiens)
FUNDC1 is phosphorylated by CK2 (Mus musculus)
FUNDC1 is phosphorylated by CK2 (Rattus norvegicus)
FUNDC1 is phosphorylated by CK2 (Canis familiaris)
FUNDC1 is phosphorylated by CK2 (Bos taurus)
FUNDC1 is phosphorylated by CK2 (Sus scrofa)
FUNDC1 is phosphorylated by CK2 (Drosophila melanogaster)
FUNDC1 is phosphorylated by CK2 (Caenorhabditis elegans)
FUNDC1 is phosphorylated by CK2 (Dictyostelium discoideum)
FUNDC1 is phosphorylated by CK2 (Schizosaccharomyces pombe)
FUNDC1 is phosphorylated by CK2 (Saccharomyces cerevisiae)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Homo sapiens)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Mus musculus)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Rattus norvegicus)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Canis familiaris)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Bos taurus)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Sus scrofa)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Danio rerio)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Gallus gallus)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Drosophila melanogaster)
p-S13, FUNDC1 is phosphorylated by CK2 at Tyr18 (Caenorhabditis elegans)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Homo sapiens)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Mus musculus)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Rattus norvegicus)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Canis familiaris)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Bos taurus)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Sus scrofa)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Xenopus tropicalis)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Gallus gallus)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Drosophila melanogaster)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Caenorhabditis elegans)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Dictyostelium discoideum)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Schizosaccharomyces pombe)
FUNDC1 is phosphorylated by ULK1 at Ser17 (Saccharomyces cerevisiae)
ULK1 phosphorylates AMBRA1:BECN1 complex (Homo sapiens)
ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)
Thr-180 of ULK1 is phosphorylated (Homo sapiens)
AMPK (complex) phosphorylates ULK1 (complex) (Homo sapiens)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
Activation of cytosolic AMPK by phosphorylation (Homo sapiens)
Activation of cytosolic AMPK by phosphorylation (Mus musculus)
Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)
Activation of cytosolic AMPK by phosphorylation (Canis familiaris)
Activation of cytosolic AMPK by phosphorylation (Bos taurus)
Activation of cytosolic AMPK by phosphorylation (Sus scrofa)
as a member of
(d)NDPs [cytosol]
Purine nucleotide [cytosol]
(d)ADP [cytosol]
This entity regulates
Negatively
KHK dimer phosphorylates Fru to Fru 1-P
(Dictyostelium discoideum)
KHK dimer phosphorylates Fru to Fru 1-P
(Drosophila melanogaster)
KHK dimer phosphorylates Fru to Fru 1-P
(Gallus gallus)
KHK dimer phosphorylates Fru to Fru 1-P
(Sus scrofa)
KHK dimer phosphorylates Fru to Fru 1-P
(Bos taurus)
KHK dimer phosphorylates Fru to Fru 1-P
(Rattus norvegicus)
KHK dimer phosphorylates Fru to Fru 1-P
(Mus musculus)
KHK dimer phosphorylates Fru to Fru 1-P
(Homo sapiens)
Positively
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Danio rerio)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Homo sapiens)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Danio rerio)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Danio rerio)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Drosophila melanogaster)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Danio rerio)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Gallus gallus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Xenopus tropicalis)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Bos taurus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Gallus gallus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Xenopus tropicalis)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Bos taurus)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Gallus gallus)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Xenopus tropicalis)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Bos taurus)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Homo sapiens)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Saccharomyces cerevisiae)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Gallus gallus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Bos taurus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Rattus norvegicus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Rattus norvegicus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Homo sapiens)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Rattus norvegicus)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Mus musculus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Rattus norvegicus)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Mus musculus)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Sus scrofa)
(d)CMP, TMP, or (d)UMP + H2O => (deoxy)cytidine, thymidine, or (deoxy)uridine + orthophosphate (NT5C1A)
(Canis familiaris)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Sus scrofa)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A)
(Canis familiaris)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Sus scrofa)
AMP + H2O => adenosine + orthophosphate [NT5C1B]
(Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Schizosaccharomyces pombe)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Caenorhabditis elegans)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Sus scrofa)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Canis familiaris)
D-fructose 6-phosphate + ATP => D-fructose 1,6-bisphosphate + ADP
(Homo sapiens)
Other forms of this molecule
ADP [mitochondrial intermembrane space]
ADP [platelet dense granule lumen]
ADP [plasma membrane]
ADP [cilium]
ADP [endoplasmic reticulum lumen]
ADP [endoplasmic reticulum membrane]
ADP [extracellular region]
ADP [mitochondrial matrix]
ADP [nucleoplasm]
Cross References
COMPOUND
C00008
ZINC
000012360703
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