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What is Reactome ?
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Digital Preservation
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L-Lys [mitochondrial matrix]
Stable Identifier
R-ALL-29444
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
Lysine acid, L-lysinium(1+), L-lysine, 2,6-diaminohexanoic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Lysine catabolism (Bos taurus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Biotin transport and metabolism (Bos taurus)
Mitochondrial BTD hydrolyses BCTN (Bos taurus)
L-Lys [mitochondrial matrix]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Amino acid transport across the plasma membrane (Bos taurus)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Bos taurus)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Lysine catabolism (Caenorhabditis elegans)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
L-Lys [mitochondrial matrix]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Amino acid transport across the plasma membrane (Caenorhabditis elegans)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Caenorhabditis elegans)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Lysine catabolism (Canis familiaris)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Biotin transport and metabolism (Canis familiaris)
Mitochondrial BTD hydrolyses BCTN (Canis familiaris)
L-Lys [mitochondrial matrix]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Amino acid transport across the plasma membrane (Canis familiaris)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Canis familiaris)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Lysine catabolism (Danio rerio)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Biotin transport and metabolism (Danio rerio)
Mitochondrial BTD hydrolyses BCTN (Danio rerio)
L-Lys [mitochondrial matrix]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Amino acid transport across the plasma membrane (Danio rerio)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Danio rerio)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Lysine catabolism (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Biotin transport and metabolism (Dictyostelium discoideum)
Mitochondrial BTD hydrolyses BCTN (Dictyostelium discoideum)
L-Lys [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Lysine catabolism (Drosophila melanogaster)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Biotin transport and metabolism (Drosophila melanogaster)
Mitochondrial BTD hydrolyses BCTN (Drosophila melanogaster)
L-Lys [mitochondrial matrix]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Amino acid transport across the plasma membrane (Drosophila melanogaster)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Drosophila melanogaster)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Lysine catabolism (Gallus gallus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Biotin transport and metabolism (Gallus gallus)
Mitochondrial BTD hydrolyses BCTN (Gallus gallus)
L-Lys [mitochondrial matrix]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Amino acid transport across the plasma membrane (Gallus gallus)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Gallus gallus)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Lysine catabolism (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Biotin transport and metabolism (Homo sapiens)
Mitochondrial BTD hydrolyses BCTN (Homo sapiens)
L-Lys [mitochondrial matrix]
Metabolism of proteins (Homo sapiens)
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Mitochondrial tRNA aminoacylation (Homo sapiens)
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
L-Lys [mitochondrial matrix]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of inorganic cations/anions and amino acids/oligopeptides (Homo sapiens)
Amino acid transport across the plasma membrane (Homo sapiens)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Homo sapiens)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Lysine catabolism (Mus musculus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Biotin transport and metabolism (Mus musculus)
Mitochondrial BTD hydrolyses BCTN (Mus musculus)
L-Lys [mitochondrial matrix]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Mus musculus)
Amino acid transport across the plasma membrane (Mus musculus)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Mus musculus)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Lysine catabolism (Rattus norvegicus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Biotin transport and metabolism (Rattus norvegicus)
Mitochondrial BTD hydrolyses BCTN (Rattus norvegicus)
L-Lys [mitochondrial matrix]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of inorganic cations/anions and amino acids/oligopeptides (Rattus norvegicus)
Amino acid transport across the plasma membrane (Rattus norvegicus)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Rattus norvegicus)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Lysine catabolism (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
L-Lys [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Lysine catabolism (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
L-Lys [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Lysine catabolism (Sus scrofa)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Biotin transport and metabolism (Sus scrofa)
Mitochondrial BTD hydrolyses BCTN (Sus scrofa)
L-Lys [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Lysine catabolism (Xenopus tropicalis)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Xenopus tropicalis)
L-Lys [mitochondrial matrix]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Biotin transport and metabolism (Xenopus tropicalis)
Mitochondrial BTD hydrolyses BCTN (Xenopus tropicalis)
L-Lys [mitochondrial matrix]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of inorganic cations/anions and amino acids/oligopeptides (Xenopus tropicalis)
Amino acid transport across the plasma membrane (Xenopus tropicalis)
SLC25A29 transports basic amino acids from cytosol to mitochondrial matrix (Xenopus tropicalis)
SLC25A29 substrates [mitochondrial matrix]
L-Lys [mitochondrial matrix]
External Reference Information
External Reference
L-lysinium(1+) [ChEBI:32551]
Participates
as an input of
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Saccharomyces cerevisiae)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Schizosaccharomyces pombe)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Dictyostelium discoideum)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Caenorhabditis elegans)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Drosophila melanogaster)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Danio rerio)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Gallus gallus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Xenopus tropicalis)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Sus scrofa)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Bos taurus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Rattus norvegicus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Mus musculus)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Homo sapiens)
lysine + alpha-ketoglutarate +NADPH + H+ => saccharopine + NADP+ + H2O (Canis familiaris)
as an output of
Mitochondrial BTD hydrolyses BCTN (Dictyostelium discoideum)
Mitochondrial BTD hydrolyses BCTN (Drosophila melanogaster)
Mitochondrial BTD hydrolyses BCTN (Gallus gallus)
Mitochondrial BTD hydrolyses BCTN (Xenopus tropicalis)
Mitochondrial BTD hydrolyses BCTN (Danio rerio)
Mitochondrial BTD hydrolyses BCTN (Sus scrofa)
Mitochondrial BTD hydrolyses BCTN (Bos taurus)
Mitochondrial BTD hydrolyses BCTN (Canis familiaris)
Mitochondrial BTD hydrolyses BCTN (Rattus norvegicus)
Mitochondrial BTD hydrolyses BCTN (Mus musculus)
Mitochondrial BTD hydrolyses BCTN (Homo sapiens)
as a member of
SLC25A29 substrates [mitochondrial matrix]
Other forms of this molecule
L-Lys [secretory granule lumen]
L-lysine [cytoplasm]
L-Lys [lysosomal lumen]
L-Lys [cytosol]
L-Lys [extracellular region]
Cross References
COMPOUND
C00047
ZINC
000001532522
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