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CAR [cytosol]
Stable Identifier
R-ALL-30235
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
(R)-carnitine, gamma-Trimethyl-hydroxybutyrobetaine, carnitine, 3-Hydroxy-4-trimethylammoniobutanoate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Carnitine synthesis (Bos taurus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)
CAR [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Carnitine shuttle (Bos taurus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Bos taurus)
CAR [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Organic cation/anion/zwitterion transport (Bos taurus)
Organic cation transport (Bos taurus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Bos taurus)
CAR [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Carnitine synthesis (Caenorhabditis elegans)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)
CAR [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine shuttle (Caenorhabditis elegans)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Caenorhabditis elegans)
CAR [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic cation transport (Caenorhabditis elegans)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
CAR [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Carnitine synthesis (Canis familiaris)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Canis familiaris)
CAR [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine shuttle (Canis familiaris)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Canis familiaris)
CAR [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic cation transport (Canis familiaris)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Canis familiaris)
CAR [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Carnitine synthesis (Danio rerio)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)
CAR [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Carnitine shuttle (Danio rerio)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Danio rerio)
CAR [cytosol]
Transport of small molecules (Danio rerio)
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Organic cation/anion/zwitterion transport (Danio rerio)
Organic cation transport (Danio rerio)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Danio rerio)
CAR [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Carnitine synthesis (Drosophila melanogaster)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)
CAR [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine shuttle (Drosophila melanogaster)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Drosophila melanogaster)
CAR [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic cation transport (Drosophila melanogaster)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Drosophila melanogaster)
CAR [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Carnitine synthesis (Gallus gallus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Gallus gallus)
CAR [cytosol]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Carnitine shuttle (Gallus gallus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Gallus gallus)
CAR [cytosol]
Transport of small molecules (Gallus gallus)
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Organic cation/anion/zwitterion transport (Gallus gallus)
Organic cation transport (Gallus gallus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Gallus gallus)
CAR [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Carnitine synthesis (Homo sapiens)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Homo sapiens)
CAR [cytosol]
Unknown carnitine exporter transports CAR from the cytosol to the extracellular space (Homo sapiens)
CAR [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine shuttle (Homo sapiens)
CAR translocates from the cytosol to the mitochondrial intermembrane space (Homo sapiens)
CAR [cytosol]
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Homo sapiens)
CAR [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Organic cation/anion/zwitterion transport (Homo sapiens)
Organic cation transport (Homo sapiens)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Homo sapiens)
CAR [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Carnitine synthesis (Mus musculus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Mus musculus)
CAR [cytosol]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Carnitine shuttle (Mus musculus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Mus musculus)
CAR [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Organic cation/anion/zwitterion transport (Mus musculus)
Organic cation transport (Mus musculus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Mus musculus)
CAR [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Carnitine synthesis (Rattus norvegicus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Rattus norvegicus)
CAR [cytosol]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Carnitine shuttle (Rattus norvegicus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Rattus norvegicus)
CAR [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Organic cation/anion/zwitterion transport (Rattus norvegicus)
Organic cation transport (Rattus norvegicus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Rattus norvegicus)
CAR [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Carnitine synthesis (Saccharomyces cerevisiae)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)
CAR [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Carnitine synthesis (Sus scrofa)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Sus scrofa)
CAR [cytosol]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Carnitine shuttle (Sus scrofa)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Sus scrofa)
CAR [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Organic cation/anion/zwitterion transport (Sus scrofa)
Organic cation transport (Sus scrofa)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Sus scrofa)
CAR [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Carnitine synthesis (Xenopus tropicalis)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Xenopus tropicalis)
CAR [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Carnitine shuttle (Xenopus tropicalis)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Xenopus tropicalis)
CAR [cytosol]
Transport of small molecules (Xenopus tropicalis)
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Organic cation/anion/zwitterion transport (Xenopus tropicalis)
Organic cation transport (Xenopus tropicalis)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Xenopus tropicalis)
CAR [cytosol]
External Reference Information
External Reference
(R)-carnitine [ChEBI:16347]
Participates
as an output of
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Drosophila melanogaster)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Gallus gallus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Xenopus tropicalis)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Danio rerio)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Sus scrofa)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Bos taurus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Canis familiaris)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Rattus norvegicus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Mus musculus)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Homo sapiens)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Caenorhabditis elegans)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Drosophila melanogaster)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Gallus gallus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Xenopus tropicalis)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Danio rerio)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Sus scrofa)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Bos taurus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Canis familiaris)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Rattus norvegicus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Mus musculus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Saccharomyces cerevisiae)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Caenorhabditis elegans)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Drosophila melanogaster)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Gallus gallus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Xenopus tropicalis)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Danio rerio)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Sus scrofa)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Bos taurus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Canis familiaris)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Rattus norvegicus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Mus musculus)
BBOX1:AscH-:Fe2+ dimer dioxygenates TEABT and 2OG to form CAR and SUCCA (Homo sapiens)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Homo sapiens)
as an input of
Unknown carnitine exporter transports CAR from the cytosol to the extracellular space (Homo sapiens)
CAR translocates from the cytosol to the mitochondrial intermembrane space (Homo sapiens)
Other forms of this molecule
CAR [extracellular region]
CAR [mitochondrial intermembrane space]
CAR [mitochondrial matrix]
CAR [peroxisomal matrix]
Cross References
Guide to Pharmacology - Ligands
4780
COMPOUND
C00487
,
C00318
HMDB Metabolite
HMDB0000062
ZINC
ZINC000003079340
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