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3-hydroxybutyric acid [extracellular region]
Stable Identifier
R-ALL-3296310
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Mus musculus
Rattus norvegicus
Sus scrofa
Expand all
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
HCAR2 binds HCAR2 ligands (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Bos taurus)
HCAR2 binds HCAR2 ligands (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Bos taurus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
HCAR2 binds HCAR2 ligands (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Canis familiaris)
HCAR2 binds HCAR2 ligands (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Canis familiaris)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
HCAR2:HCAR2 ligands [plasma membrane] (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
HCAR2:HCAR2 ligands [plasma membrane] (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
HCAR2 binds HCAR2 ligands (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Danio rerio)
HCAR2 binds HCAR2 ligands (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Danio rerio)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
HCAR2 binds HCAR2 ligands (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Homo sapiens)
HCAR2 binds HCAR2 ligands (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Homo sapiens)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
HCAR2 binds HCAR2 ligands (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Mus musculus)
HCAR2 binds HCAR2 ligands (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Mus musculus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
HCAR2:HCAR2 ligands [plasma membrane] (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
HCAR2:HCAR2 ligands [plasma membrane] (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
HCAR2 binds HCAR2 ligands (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Rattus norvegicus)
HCAR2 binds HCAR2 ligands (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Rattus norvegicus)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
HCAR2 binds HCAR2 ligands (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
Hydroxycarboxylic acid-binding receptors (Sus scrofa)
HCAR2 binds HCAR2 ligands (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
HCAR2:HCAR2 ligands [plasma membrane] (Sus scrofa)
HCAR2 ligands [extracellular region]
3-hydroxybutyric acid [extracellular region]
External Reference Information
External Reference
3-hydroxybutyric acid [ChEBI:20067]
Participates
as a member of
HCAR2 ligands [extracellular region]
Cross References
Guide to Pharmacology - Ligands
1593
ZINC
000000901665
,
000000895486
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