Ligands of PPARA [nucleoplasm]

Stable Identifier
R-ALL-400149
Type
Set [DefinedSet]
Compartment
nucleoplasm
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General
PPAR-alpha is most efficiently activated by polyunsaturated fatty acids having 18-20 carbon groups and 3-5 double bonds.
Literature References
PubMed ID Title Journal Year
9171241 Fatty acids, eicosanoids, and hypolipidemic agents identified as ligands of peroxisome proliferator-activated receptors by coactivator-dependent receptor ligand assay

Krey, G, Kalkhoven, E, Braissant, O, Parker, MG, Wahli, W, L'Horset, F, Perroud, M

Mol Endocrinol 1997
17007889 Selectivity of fatty acid ligands for PPARalpha which correlates both with binding to cis-element and DNA binding-independent transactivity in Caco-2 cells

Goda, T, Takase, S, Kiso, Y, Mochizuki, K, Fukami, H, Suruga, K

Life Sci 2006
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