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About
What is Reactome ?
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Digital Preservation
Contact us
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How do I search ?
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FFAR1 ligands [extracellular region]
Stable Identifier
R-ALL-400427
Type
Set [DefinedSet]
Compartment
extracellular region
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Free fatty acids regulate insulin secretion (Bos taurus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Bos taurus)
FFAR1 binds fatty acids (Bos taurus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Metabolism of proteins (Bos taurus)
Peptide hormone metabolism (Bos taurus)
Incretin synthesis, secretion, and inactivation (Bos taurus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Bos taurus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Bos taurus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
FFAR1 ligands [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Free fatty acid receptors (Bos taurus)
Receptor FFAR1 binds free fatty acids (Bos taurus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1 ligands [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
FFAR1 ligands [extracellular region]
Metabolism (Canis familiaris)
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Free fatty acids regulate insulin secretion (Canis familiaris)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Canis familiaris)
FFAR1 binds fatty acids (Canis familiaris)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Metabolism of proteins (Canis familiaris)
Peptide hormone metabolism (Canis familiaris)
Incretin synthesis, secretion, and inactivation (Canis familiaris)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Canis familiaris)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Canis familiaris)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (q) signalling events (Canis familiaris)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
FFAR1 ligands [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Free fatty acid receptors (Canis familiaris)
Receptor FFAR1 binds free fatty acids (Canis familiaris)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1 ligands [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
FFAR1 ligands [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (q) signalling events (Gallus gallus)
The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
FFAR1 ligands [extracellular region]
Metabolism (Homo sapiens)
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Free fatty acids regulate insulin secretion (Homo sapiens)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Homo sapiens)
FFAR1 binds fatty acids (Homo sapiens)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Metabolism of proteins (Homo sapiens)
Peptide hormone metabolism (Homo sapiens)
Incretin synthesis, secretion, and inactivation (Homo sapiens)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Homo sapiens)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Homo sapiens)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
FFAR1 ligands [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Free fatty acid receptors (Homo sapiens)
Receptor FFAR1 binds free fatty acids (Homo sapiens)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
FFAR1 ligands [extracellular region]
Metabolism (Mus musculus)
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Free fatty acids regulate insulin secretion (Mus musculus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Mus musculus)
FFAR1 binds fatty acids (Mus musculus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Metabolism of proteins (Mus musculus)
Peptide hormone metabolism (Mus musculus)
Incretin synthesis, secretion, and inactivation (Mus musculus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Mus musculus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Mus musculus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (q) signalling events (Mus musculus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
FFAR1 ligands [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Free fatty acid receptors (Mus musculus)
Receptor FFAR1 binds free fatty acids (Mus musculus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1 ligands [extracellular region]
Metabolism (Rattus norvegicus)
Integration of energy metabolism (Rattus norvegicus)
Regulation of insulin secretion (Rattus norvegicus)
Free fatty acids regulate insulin secretion (Rattus norvegicus)
Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion (Rattus norvegicus)
FFAR1 binds fatty acids (Rattus norvegicus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands activate Gq (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
Metabolism of proteins (Rattus norvegicus)
Peptide hormone metabolism (Rattus norvegicus)
Incretin synthesis, secretion, and inactivation (Rattus norvegicus)
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) (Rattus norvegicus)
Glucagon-like Peptide 1 is secreted from intestinal L cells (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP) (Rattus norvegicus)
Glucose-dependent Insulinotropic Polypeptide is secreted from intestinal K cells (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Free fatty acid receptors (Rattus norvegicus)
Receptor FFAR1 binds free fatty acids (Rattus norvegicus)
FFAR1 ligands [extracellular region]
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1 ligands [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (q) signalling events (Sus scrofa)
The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
FFAR1 ligands [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (q) signalling events (Xenopus tropicalis)
The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
FFAR1 ligands [extracellular region]
Participants
members
PALM [extracellular region]
Pentadecanoic acid [extracellular region]
OLEA [extracellular region]
DDCX [extracellular region]
RGZ [extracellular region]
Participates
as an input of
FFAR1 binds fatty acids (Bos taurus)
FFAR1 binds fatty acids (Canis familiaris)
FFAR1 binds fatty acids (Rattus norvegicus)
FFAR1 binds fatty acids (Mus musculus)
FFAR1 binds fatty acids (Homo sapiens)
Receptor FFAR1 binds free fatty acids (Bos taurus)
Receptor FFAR1 binds free fatty acids (Canis familiaris)
Receptor FFAR1 binds free fatty acids (Rattus norvegicus)
Receptor FFAR1 binds free fatty acids (Mus musculus)
Receptor FFAR1 binds free fatty acids (Homo sapiens)
as a member of
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
as a component of
FFAR1:FFAR1 ligands [plasma membrane] (Bos taurus)
FFAR1:FFAR1 ligands [plasma membrane] (Rattus norvegicus)
FFAR1:FFAR1 ligands [plasma membrane] (Canis familiaris)
FFAR1:FFAR1 ligands [plasma membrane] (Mus musculus)
FFAR1:FFAR1 ligands [plasma membrane] (Homo sapiens)
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