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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
Review Status of Reactome Events
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Developer's Zone
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Pathway Diagrams
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FAQ
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Citing us
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Analyse gene list
Analyse gene expression
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Search ...
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LPA [extracellular region]
Stable Identifier
R-ALL-417891
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
Lysophosphatidic acid, 1-octadec-9-enoylglycero-3-phosphate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
G alpha (q) signalling events (Bos taurus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
LPA [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Lysosphingolipid and LPA receptors (Bos taurus)
LPA-binding receptors bind LPA (Bos taurus)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Bos taurus)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Bos taurus)
P2Y receptors (Bos taurus)
P2Y10 receptor can bind to LPA (Bos taurus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Bos taurus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Bos taurus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Bos taurus)
LPA [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Caenorhabditis elegans)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Caenorhabditis elegans)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
LPA [extracellular region]
GPCR ligand binding (Caenorhabditis elegans)
Class A/1 (Rhodopsin-like receptors) (Caenorhabditis elegans)
Lysosphingolipid and LPA receptors (Caenorhabditis elegans)
LRPP4(LRPP1-3,5) hydrolyse LPA (Caenorhabditis elegans)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Caenorhabditis elegans)
P2Y receptors (Caenorhabditis elegans)
P2Y10 receptor can bind to LPA (Caenorhabditis elegans)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Caenorhabditis elegans)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Caenorhabditis elegans)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
LPA [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Liganded Gi-activating GPCR acts as a GEF for Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
G alpha (q) signalling events (Canis familiaris)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
LPA [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Lysosphingolipid and LPA receptors (Canis familiaris)
LPA-binding receptors bind LPA (Canis familiaris)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Canis familiaris)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Canis familiaris)
P2Y receptors (Canis familiaris)
P2Y10 receptor can bind to LPA (Canis familiaris)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Canis familiaris)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Canis familiaris)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Canis familiaris)
LPA [extracellular region]
Signal Transduction (Danio rerio)
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (i) signalling events (Danio rerio)
Liganded Gi-activating GPCR acts as a GEF for Gi (Danio rerio)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Danio rerio)
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
G alpha (q) signalling events (Danio rerio)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Danio rerio)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Danio rerio)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Danio rerio)
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
GPCR ligand binding (Danio rerio)
Class A/1 (Rhodopsin-like receptors) (Danio rerio)
Lysosphingolipid and LPA receptors (Danio rerio)
LPA-binding receptors bind LPA (Danio rerio)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Danio rerio)
P2Y receptors (Danio rerio)
P2Y10 receptor can bind to LPA (Danio rerio)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Danio rerio)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Danio rerio)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Danio rerio)
LPA [extracellular region]
Signal Transduction (Dictyostelium discoideum)
Signaling by GPCR (Dictyostelium discoideum)
GPCR ligand binding (Dictyostelium discoideum)
Class A/1 (Rhodopsin-like receptors) (Dictyostelium discoideum)
Lysosphingolipid and LPA receptors (Dictyostelium discoideum)
LRPP4(LRPP1-3,5) hydrolyse LPA (Dictyostelium discoideum)
LPA [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
LPA [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
G alpha (q) signalling events (Gallus gallus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
LPA [extracellular region]
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Lysosphingolipid and LPA receptors (Gallus gallus)
LPA-binding receptors bind LPA (Gallus gallus)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Gallus gallus)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Gallus gallus)
P2Y receptors (Gallus gallus)
P2Y10 receptor can bind to LPA (Gallus gallus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Gallus gallus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Gallus gallus)
LPA [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Liganded Gi-activating GPCR acts as a GEF for Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
LPA [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Lysosphingolipid and LPA receptors (Homo sapiens)
LPA-binding receptors bind LPA (Homo sapiens)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Homo sapiens)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Homo sapiens)
P2Y receptors (Homo sapiens)
P2Y10 receptor can bind to LPA (Homo sapiens)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Homo sapiens)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Homo sapiens)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Homo sapiens)
LPA [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
G alpha (q) signalling events (Mus musculus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
LPA [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Lysosphingolipid and LPA receptors (Mus musculus)
LPA-binding receptors bind LPA (Mus musculus)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Mus musculus)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Mus musculus)
P2Y receptors (Mus musculus)
P2Y10 receptor can bind to LPA (Mus musculus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Mus musculus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Mus musculus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Mus musculus)
LPA [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Liganded Gi-activating GPCR acts as a GEF for Gi (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Rattus norvegicus)
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
G alpha (q) signalling events (Rattus norvegicus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Lysosphingolipid and LPA receptors (Rattus norvegicus)
LPA-binding receptors bind LPA (Rattus norvegicus)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Rattus norvegicus)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Rattus norvegicus)
P2Y receptors (Rattus norvegicus)
P2Y10 receptor can bind to LPA (Rattus norvegicus)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Rattus norvegicus)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Rattus norvegicus)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Rattus norvegicus)
LPA [extracellular region]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by GPCR (Saccharomyces cerevisiae)
GPCR ligand binding (Saccharomyces cerevisiae)
Class A/1 (Rhodopsin-like receptors) (Saccharomyces cerevisiae)
Lysosphingolipid and LPA receptors (Saccharomyces cerevisiae)
LRPP4(LRPP1-3,5) hydrolyse LPA (Saccharomyces cerevisiae)
LPA [extracellular region]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by GPCR (Schizosaccharomyces pombe)
GPCR ligand binding (Schizosaccharomyces pombe)
Class A/1 (Rhodopsin-like receptors) (Schizosaccharomyces pombe)
Lysosphingolipid and LPA receptors (Schizosaccharomyces pombe)
LRPP4(LRPP1-3,5) hydrolyse LPA (Schizosaccharomyces pombe)
LPA [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Liganded Gi-activating GPCR acts as a GEF for Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
G alpha (q) signalling events (Sus scrofa)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
LPA [extracellular region]
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Lysosphingolipid and LPA receptors (Sus scrofa)
LPA-binding receptors bind LPA (Sus scrofa)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Sus scrofa)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Sus scrofa)
P2Y receptors (Sus scrofa)
P2Y10 receptor can bind to LPA (Sus scrofa)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Sus scrofa)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Sus scrofa)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Sus scrofa)
LPA [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Liganded Gi-activating GPCR acts as a GEF for Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Liganded Gi-activating GPCRs bind inactive heterotrimeric G-protein Gi (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
The Ligand:GPCR:Gi complex dissociates (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gi:Heterotrimeric G-protein Gi (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gi [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
G alpha (q) signalling events (Xenopus tropicalis)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
LPA [extracellular region]
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Lysosphingolipid and LPA receptors (Xenopus tropicalis)
LPA-binding receptors bind LPA (Xenopus tropicalis)
LPA [extracellular region]
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
LRPP4(LRPP1-3,5) hydrolyse LPA (Xenopus tropicalis)
LPA [extracellular region]
Nucleotide-like (purinergic) receptors (Xenopus tropicalis)
P2Y receptors (Xenopus tropicalis)
P2Y10 receptor can bind to LPA (Xenopus tropicalis)
LPA [extracellular region]
P2RY10:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2Y5 receptor can bind to LPA (Xenopus tropicalis)
LPA [extracellular region]
P2RY5:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
P2Y9 receptor can bind to LPA (Xenopus tropicalis)
LPA [extracellular region]
P2RY9:LPA [plasma membrane] (Xenopus tropicalis)
LPA [extracellular region]
External Reference Information
External Reference
1-octadec-9-enoylglycero-3-phosphate [ChEBI:52288]
Participates
as a component of
LPAR1,2,3,5:LPA [plasma membrane] (Homo sapiens)
LPAR1,2,3,5:LPA [plasma membrane] (Xenopus tropicalis)
LPAR1,2,3,5:LPA [plasma membrane] (Gallus gallus)
LPAR1,2,3,5:LPA [plasma membrane] (Mus musculus)
LPAR1,2,3,5:LPA [plasma membrane] (Sus scrofa)
LPAR1,2,3,5:LPA [plasma membrane] (Danio rerio)
LPAR1,2,3,5:LPA [plasma membrane] (Canis familiaris)
LPAR1,2,3,5:LPA [plasma membrane] (Bos taurus)
LPAR1,2,3,5:LPA [plasma membrane] (Rattus norvegicus)
P2RY5:LPA [plasma membrane] (Homo sapiens)
P2RY5:LPA [plasma membrane] (Danio rerio)
P2RY5:LPA [plasma membrane] (Rattus norvegicus)
P2RY5:LPA [plasma membrane] (Bos taurus)
P2RY5:LPA [plasma membrane] (Xenopus tropicalis)
P2RY5:LPA [plasma membrane] (Caenorhabditis elegans)
P2RY5:LPA [plasma membrane] (Sus scrofa)
P2RY5:LPA [plasma membrane] (Mus musculus)
P2RY5:LPA [plasma membrane] (Canis familiaris)
P2RY9:LPA [plasma membrane] (Homo sapiens)
P2RY9:LPA [plasma membrane] (Rattus norvegicus)
P2RY9:LPA [plasma membrane] (Caenorhabditis elegans)
P2RY9:LPA [plasma membrane] (Gallus gallus)
P2RY9:LPA [plasma membrane] (Danio rerio)
P2RY9:LPA [plasma membrane] (Bos taurus)
P2RY9:LPA [plasma membrane] (Xenopus tropicalis)
P2RY9:LPA [plasma membrane] (Canis familiaris)
P2RY9:LPA [plasma membrane] (Sus scrofa)
P2RY9:LPA [plasma membrane] (Mus musculus)
P2RY10:LPA [plasma membrane] (Homo sapiens)
P2RY10:LPA [plasma membrane] (Xenopus tropicalis)
P2RY10:LPA [plasma membrane] (Gallus gallus)
P2RY10:LPA [plasma membrane] (Sus scrofa)
P2RY10:LPA [plasma membrane] (Rattus norvegicus)
P2RY10:LPA [plasma membrane] (Bos taurus)
P2RY10:LPA [plasma membrane] (Mus musculus)
P2RY10:LPA [plasma membrane] (Canis familiaris)
P2RY10:LPA [plasma membrane] (Danio rerio)
P2RY10:LPA [plasma membrane] (Caenorhabditis elegans)
as an input of
LPA-binding receptors bind LPA (Gallus gallus)
LPA-binding receptors bind LPA (Xenopus tropicalis)
LPA-binding receptors bind LPA (Danio rerio)
LPA-binding receptors bind LPA (Sus scrofa)
LPA-binding receptors bind LPA (Bos taurus)
LPA-binding receptors bind LPA (Canis familiaris)
LPA-binding receptors bind LPA (Rattus norvegicus)
LPA-binding receptors bind LPA (Mus musculus)
LPA-binding receptors bind LPA (Homo sapiens)
LRPP4(LRPP1-3,5) hydrolyse LPA (Saccharomyces cerevisiae)
LRPP4(LRPP1-3,5) hydrolyse LPA (Schizosaccharomyces pombe)
LRPP4(LRPP1-3,5) hydrolyse LPA (Dictyostelium discoideum)
LRPP4(LRPP1-3,5) hydrolyse LPA (Caenorhabditis elegans)
LRPP4(LRPP1-3,5) hydrolyse LPA (Gallus gallus)
LRPP4(LRPP1-3,5) hydrolyse LPA (Xenopus tropicalis)
LRPP4(LRPP1-3,5) hydrolyse LPA (Sus scrofa)
LRPP4(LRPP1-3,5) hydrolyse LPA (Bos taurus)
LRPP4(LRPP1-3,5) hydrolyse LPA (Canis familiaris)
LRPP4(LRPP1-3,5) hydrolyse LPA (Rattus norvegicus)
LRPP4(LRPP1-3,5) hydrolyse LPA (Mus musculus)
LRPP4(LRPP1-3,5) hydrolyse LPA (Homo sapiens)
P2Y10 receptor can bind to LPA (Caenorhabditis elegans)
P2Y10 receptor can bind to LPA (Gallus gallus)
P2Y10 receptor can bind to LPA (Xenopus tropicalis)
P2Y10 receptor can bind to LPA (Danio rerio)
P2Y10 receptor can bind to LPA (Sus scrofa)
P2Y10 receptor can bind to LPA (Bos taurus)
P2Y10 receptor can bind to LPA (Canis familiaris)
P2Y10 receptor can bind to LPA (Rattus norvegicus)
P2Y10 receptor can bind to LPA (Mus musculus)
P2Y10 receptor can bind to LPA (Homo sapiens)
P2Y5 receptor can bind to LPA (Caenorhabditis elegans)
P2Y5 receptor can bind to LPA (Xenopus tropicalis)
P2Y5 receptor can bind to LPA (Danio rerio)
P2Y5 receptor can bind to LPA (Sus scrofa)
P2Y5 receptor can bind to LPA (Bos taurus)
P2Y5 receptor can bind to LPA (Canis familiaris)
P2Y5 receptor can bind to LPA (Rattus norvegicus)
P2Y5 receptor can bind to LPA (Mus musculus)
P2Y5 receptor can bind to LPA (Homo sapiens)
P2Y9 receptor can bind to LPA (Caenorhabditis elegans)
P2Y9 receptor can bind to LPA (Gallus gallus)
P2Y9 receptor can bind to LPA (Xenopus tropicalis)
P2Y9 receptor can bind to LPA (Danio rerio)
P2Y9 receptor can bind to LPA (Sus scrofa)
P2Y9 receptor can bind to LPA (Bos taurus)
P2Y9 receptor can bind to LPA (Canis familiaris)
P2Y9 receptor can bind to LPA (Rattus norvegicus)
P2Y9 receptor can bind to LPA (Mus musculus)
P2Y9 receptor can bind to LPA (Homo sapiens)
as a member of
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
Other forms of this molecule
LPA [mitochondrial intermembrane space]
Cross References
HMDB Metabolite
HMDB0242470
ZINC
000014953268
,
000014953257
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