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Fe2+ [extracellular region]
Stable Identifier
R-ALL-435347
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
iron (ferrous), Fe(II), Fe++
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Transport of small molecules (Bos taurus)
Iron uptake and transport (Bos taurus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Bos taurus)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Bos taurus)
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Metal ion SLC transporters (Bos taurus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
Fe2+ [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
Iron uptake and transport (Caenorhabditis elegans)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Caenorhabditis elegans)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Caenorhabditis elegans)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Metal ion SLC transporters (Caenorhabditis elegans)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Caenorhabditis elegans)
Fe2+ [extracellular region]
Transport of small molecules (Canis familiaris)
Iron uptake and transport (Canis familiaris)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Canis familiaris)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Canis familiaris)
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Metal ion SLC transporters (Canis familiaris)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
Fe2+ [extracellular region]
Transport of small molecules (Danio rerio)
Iron uptake and transport (Danio rerio)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Danio rerio)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Danio rerio)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Danio rerio)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Danio rerio)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Danio rerio)
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Metal ion SLC transporters (Danio rerio)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Danio rerio)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Danio rerio)
Fe2+ [extracellular region]
Transport of small molecules (Dictyostelium discoideum)
Iron uptake and transport (Dictyostelium discoideum)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Dictyostelium discoideum)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of bile salts and organic acids, metal ions and amine compounds (Dictyostelium discoideum)
Metal ion SLC transporters (Dictyostelium discoideum)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Dictyostelium discoideum)
Fe2+ [extracellular region]
Transport of small molecules (Drosophila melanogaster)
Iron uptake and transport (Drosophila melanogaster)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Drosophila melanogaster)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Drosophila melanogaster)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Metal ion SLC transporters (Drosophila melanogaster)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Drosophila melanogaster)
Fe2+ [extracellular region]
Transport of small molecules (Gallus gallus)
Iron uptake and transport (Gallus gallus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Gallus gallus)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Gallus gallus)
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Metal ion SLC transporters (Gallus gallus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
Fe2+ [extracellular region]
Disease (Homo sapiens)
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective CP causes aceruloplasminemia (ACERULOP) (Homo sapiens)
Defective CP does not oxidise Fe2+ to Fe3+ (Homo sapiens)
Fe2+ [extracellular region]
Defective SLC11A2 causes hypochromic microcytic anemia, with iron overload 1 (AHMIO1) (Homo sapiens)
Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol (Homo sapiens)
Fe2+ [extracellular region]
Transport of small molecules (Homo sapiens)
Iron uptake and transport (Homo sapiens)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Homo sapiens)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Homo sapiens)
Transport of bile salts and organic acids, metal ions and amine compounds (Homo sapiens)
Metal ion SLC transporters (Homo sapiens)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
Fe2+ [extracellular region]
Transport of small molecules (Mus musculus)
Iron uptake and transport (Mus musculus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Mus musculus)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Mus musculus)
Transport of bile salts and organic acids, metal ions and amine compounds (Mus musculus)
Metal ion SLC transporters (Mus musculus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
Fe2+ [extracellular region]
Transport of small molecules (Plasmodium falciparum)
Iron uptake and transport (Plasmodium falciparum)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Plasmodium falciparum)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of bile salts and organic acids, metal ions and amine compounds (Plasmodium falciparum)
Metal ion SLC transporters (Plasmodium falciparum)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Plasmodium falciparum)
Fe2+ [extracellular region]
Transport of small molecules (Rattus norvegicus)
Iron uptake and transport (Rattus norvegicus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Rattus norvegicus)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of bile salts and organic acids, metal ions and amine compounds (Rattus norvegicus)
Metal ion SLC transporters (Rattus norvegicus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
Fe2+ [extracellular region]
Transport of small molecules (Sus scrofa)
Iron uptake and transport (Sus scrofa)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Sus scrofa)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Sus scrofa)
Transport of bile salts and organic acids, metal ions and amine compounds (Sus scrofa)
Metal ion SLC transporters (Sus scrofa)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
Fe2+ [extracellular region]
Transport of small molecules (Xenopus tropicalis)
Iron uptake and transport (Xenopus tropicalis)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC-mediated transmembrane transport (Xenopus tropicalis)
Transport of bile salts and organic acids, metal ions and amine compounds (Xenopus tropicalis)
Metal ion SLC transporters (Xenopus tropicalis)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
Fe2+ [extracellular region]
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
Fe2+ [extracellular region]
External Reference Information
External Reference
iron(2+) [ChEBI:29033]
Participates
as an input of
Defective SLC11A2 does not cotransport Fe2+, H+ from extracellular region to cytosol (Homo sapiens)
Defective CP does not oxidise Fe2+ to Fe3+ (Homo sapiens)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Gallus gallus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Sus scrofa)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Bos taurus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Drosophila melanogaster)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Homo sapiens)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Mus musculus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Rattus norvegicus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Canis familiaris)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Bos taurus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Sus scrofa)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Danio rerio)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Xenopus tropicalis)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Gallus gallus)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Caenorhabditis elegans)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Dictyostelium discoideum)
SLC11A2 cotransports Fe2+, H+ from extracellular region to cytosol (Plasmodium falciparum)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Mus musculus)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Homo sapiens)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Rattus norvegicus)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Canis familiaris)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Bos taurus)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Sus scrofa)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Danio rerio)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Xenopus tropicalis)
SLC40A1:CP:6Cu2+ oxidises Fe2+ to Fe3+ (Gallus gallus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Mus musculus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Homo sapiens)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ oxidises 4Fe2+ to 4Fe3+ (Canis familiaris)
as an output of
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Danio rerio)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
SLC40A1:CP:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Drosophila melanogaster)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Homo sapiens)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Mus musculus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Rattus norvegicus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Canis familiaris)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Bos taurus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Sus scrofa)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Danio rerio)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Xenopus tropicalis)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Gallus gallus)
CYBRD1:Heme reduces Fe3+ to Fe2+ (Caenorhabditis elegans)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Mus musculus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Homo sapiens)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Rattus norvegicus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Canis familiaris)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Bos taurus)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Sus scrofa)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Xenopus tropicalis)
SLC40A1:HEPH:6Cu2+ transports Fe2+ from cytosol to extracellular region (Gallus gallus)
Other forms of this molecule
Fe2+ [cytoplasm]
Fe2+ [endoplasmic reticulum lumen]
Fe2+ [endoplasmic reticulum membrane]
Fe2+ [peroxisomal matrix]
Fe2+ [phagocytic vesicle lumen]
Fe2+ [endosome lumen]
Fe2+ [mitochondrial inner membrane]
Fe2+ [nucleoplasm]
Fe2+ [nuclear envelope]
Fe2+ [mitochondrial intermembrane space]
Fe2+ [mitochondrial matrix]
Fe2+ [cytosol]
Cross References
AraCyc
FE+2
ChEBI
29033
COMPOUND
C14818
,
C00023
PubChem Compound
27284
HMDB Metabolite
HMDB0000692
KEGG Gene
C14818
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![Fe2+ [extracellular region] icon](/icon/R-ICO-012913.svg){kind=icon}
