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(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Stable Identifier
R-ALL-449298
Type
Chemical Compound [SimpleEntity]
Compartment
lumenal side of endoplasmic reticulum membrane
Synonyms
glycan G00006, (alpha-D-mannosyl)4-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Asparagine N-linked glycosylation (Bos taurus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Bos taurus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Bos taurus)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Asparagine N-linked glycosylation (Caenorhabditis elegans)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Caenorhabditis elegans)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Caenorhabditis elegans)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Asparagine N-linked glycosylation (Canis familiaris)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Canis familiaris)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Canis familiaris)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Asparagine N-linked glycosylation (Danio rerio)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Danio rerio)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Danio rerio)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Asparagine N-linked glycosylation (Dictyostelium discoideum)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Dictyostelium discoideum)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Dictyostelium discoideum)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Asparagine N-linked glycosylation (Drosophila melanogaster)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Drosophila melanogaster)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Drosophila melanogaster)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Asparagine N-linked glycosylation (Gallus gallus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Gallus gallus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Gallus gallus)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of glycosylation (Homo sapiens)
Diseases associated with N-glycosylation of proteins (Homo sapiens)
Defective ALG3 causes CDG-1d (Homo sapiens)
Defective ALG3 does not add mannose to the N-glycan precursor (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Defective MPDU1 causes CDG-1f (Homo sapiens)
Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Asparagine N-linked glycosylation (Homo sapiens)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Homo sapiens)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Flipping of the N-glycan precursor to inside the ER (Homo sapiens)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Asparagine N-linked glycosylation (Mus musculus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Mus musculus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Mus musculus)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Asparagine N-linked glycosylation (Rattus norvegicus)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Rattus norvegicus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Rattus norvegicus)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Asparagine N-linked glycosylation (Saccharomyces cerevisiae)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Saccharomyces cerevisiae)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Saccharomyces cerevisiae)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Asparagine N-linked glycosylation (Schizosaccharomyces pombe)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Schizosaccharomyces pombe)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Schizosaccharomyces pombe)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Asparagine N-linked glycosylation (Sus scrofa)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Sus scrofa)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Sus scrofa)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Asparagine N-linked glycosylation (Xenopus tropicalis)
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein (Xenopus tropicalis)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Xenopus tropicalis)
(GlcNAc)2 (Man)5 (PP-Dol)1 [lumenal side of endoplasmic reticulum membrane]
External Reference Information
External Reference
(alpha-D-mannosyl)4-beta-D-mannosyldiacetylchitobiosyldiphosphodolichol [ChEBI:37633]
Participates
as an input of
Defective MPDU1 does not promote transfer of Man to (GlcNAc)2 (Man)5 (PP-Dol)1 by ALG3 (Homo sapiens)
Defective ALG3 does not add mannose to the N-glycan precursor (Homo sapiens)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Saccharomyces cerevisiae)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Schizosaccharomyces pombe)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Dictyostelium discoideum)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Caenorhabditis elegans)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Drosophila melanogaster)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Gallus gallus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Xenopus tropicalis)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Danio rerio)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Sus scrofa)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Bos taurus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Rattus norvegicus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Mus musculus)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Homo sapiens)
ALG3 transfers Man to N-glycan precursor (GlcNAc)2 (Man)5 (PP-Dol)1 (Canis familiaris)
as an output of
Flipping of the N-glycan precursor into the ER lumen (Saccharomyces cerevisiae)
Flipping of the N-glycan precursor to inside the ER (Homo sapiens)
Other forms of this molecule
(GlcNAc)2 (Man)5 (PP-Dol)1 [cytoplasmic side of endoplasmic reticulum membrane]
Cross References
COMPOUND
C05864
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