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About
What is Reactome ?
News
Team
Scientific Advisory Board
Funding
Editorial Calendar
Release Calendar
Statistics
Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
Content
Table of Contents
DOIs
Data Schema
Reactome Research Spotlight
ORCID Integration Project
COVID-19 Disease Pathways
Docs
Userguide
Pathway Browser
How do I search ?
Details Panel
Analysis Tools
Analysis Data
Analysis Gene Expression
Species Comparison
Tissue Distribution
Diseases
Cytomics
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Developer's Zone
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Pathway Diagrams
Icon Info
EHLD Specs & Guidelines
Icon Library Guidelines
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FAQ
Linking to Us
Citing us
Tools
Pathway Browser
Analyse gene list
Analyse gene expression
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Search ...
Go!
atRA [nucleoplasm]
Stable Identifier
R-ALL-5334804
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
all-trans-retinoic acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Developmental Biology (Bos taurus)
Transcriptional regulation of granulopoiesis (Bos taurus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Bos taurus)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Bos taurus)
atRA:RARA:RXRA [nucleoplasm] (Bos taurus)
RARA:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Bos taurus)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Bos taurus)
NPM1 binds TFAP2A homodimer (Bos taurus)
atRA [nucleoplasm]
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Carnitine shuttle (Bos taurus)
CPT1A transfers PALM to CAR (Bos taurus)
RXRA:PPARD:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
Signaling by Retinoic Acid (Bos taurus)
FABP5 dissociates from RXRA:PPARD:atRA (Bos taurus)
RXRA:PPARD:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Bos taurus)
FABP5:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Bos taurus)
FABP5:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Bos taurus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Bos taurus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Bos taurus)
FABP5:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Bos taurus)
FABP5:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Bos taurus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Bos taurus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Bos taurus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Bos taurus)
atRA [nucleoplasm]
Developmental Biology (Caenorhabditis elegans)
Transcriptional regulation of granulopoiesis (Caenorhabditis elegans)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Caenorhabditis elegans)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA:RARA:RXRA [nucleoplasm] (Caenorhabditis elegans)
RARA:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
Metabolism (Caenorhabditis elegans)
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine shuttle (Caenorhabditis elegans)
CPT1A transfers PALM to CAR (Caenorhabditis elegans)
RXRA:PPARD:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
Signaling by Retinoic Acid (Caenorhabditis elegans)
FABP5 dissociates from RXRA:PPARD:atRA (Caenorhabditis elegans)
RXRA:PPARD:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Caenorhabditis elegans)
FABP5:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Caenorhabditis elegans)
FABP5:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Caenorhabditis elegans)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Caenorhabditis elegans)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Caenorhabditis elegans)
FABP5:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Caenorhabditis elegans)
FABP5:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Caenorhabditis elegans)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Caenorhabditis elegans)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Caenorhabditis elegans)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Caenorhabditis elegans)
atRA [nucleoplasm]
Developmental Biology (Canis familiaris)
Transcriptional regulation of granulopoiesis (Canis familiaris)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Canis familiaris)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Canis familiaris)
atRA:RARA:RXRA [nucleoplasm] (Canis familiaris)
RARA:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Canis familiaris)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Canis familiaris)
NPM1 binds TFAP2A homodimer (Canis familiaris)
atRA [nucleoplasm]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine shuttle (Canis familiaris)
CPT1A transfers PALM to CAR (Canis familiaris)
RXRA:PPARD:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
Signal Transduction (Canis familiaris)
Signaling by Nuclear Receptors (Canis familiaris)
Signaling by Retinoic Acid (Canis familiaris)
FABP5 dissociates from RXRA:PPARD:atRA (Canis familiaris)
RXRA:PPARD:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Canis familiaris)
FABP5:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Canis familiaris)
FABP5:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Canis familiaris)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Canis familiaris)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Canis familiaris)
FABP5:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Canis familiaris)
FABP5:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Canis familiaris)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Canis familiaris)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Canis familiaris)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Canis familiaris)
atRA [nucleoplasm]
Developmental Biology (Danio rerio)
Transcriptional regulation of granulopoiesis (Danio rerio)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Danio rerio)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Danio rerio)
atRA:RARA:RXRA [nucleoplasm] (Danio rerio)
RARA:atRA [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
Signal Transduction (Danio rerio)
Signaling by Nuclear Receptors (Danio rerio)
Signaling by Retinoic Acid (Danio rerio)
RAR:RXR binds SUMO-CRABP2:atRA (Danio rerio)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Danio rerio)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Danio rerio)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Danio rerio)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Danio rerio)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Danio rerio)
atRA [nucleoplasm]
Developmental Biology (Drosophila melanogaster)
Transcriptional regulation of granulopoiesis (Drosophila melanogaster)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Drosophila melanogaster)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Drosophila melanogaster)
atRA:RARA:RXRA [nucleoplasm] (Drosophila melanogaster)
RARA:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Drosophila melanogaster)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Drosophila melanogaster)
NPM1 binds TFAP2A homodimer (Drosophila melanogaster)
atRA [nucleoplasm]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine shuttle (Drosophila melanogaster)
CPT1A transfers PALM to CAR (Drosophila melanogaster)
RXRA:PPARD:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
Signaling by Retinoic Acid (Drosophila melanogaster)
RAR:RXR binds SUMO-CRABP2:atRA (Drosophila melanogaster)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Drosophila melanogaster)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Drosophila melanogaster)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Drosophila melanogaster)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Drosophila melanogaster)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Drosophila melanogaster)
atRA [nucleoplasm]
Developmental Biology (Gallus gallus)
Transcriptional regulation of granulopoiesis (Gallus gallus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Gallus gallus)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Gallus gallus)
atRA:RARA:RXRA [nucleoplasm] (Gallus gallus)
RARA:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Gallus gallus)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Gallus gallus)
NPM1 binds TFAP2A homodimer (Gallus gallus)
atRA [nucleoplasm]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Carnitine shuttle (Gallus gallus)
CPT1A transfers PALM to CAR (Gallus gallus)
RXRA:PPARD:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
Signaling by Retinoic Acid (Gallus gallus)
FABP5 dissociates from RXRA:PPARD:atRA (Gallus gallus)
RXRA:PPARD:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Gallus gallus)
FABP5:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Gallus gallus)
FABP5:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Gallus gallus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Gallus gallus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Gallus gallus)
FABP5:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Gallus gallus)
FABP5:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Gallus gallus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Gallus gallus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Gallus gallus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Gallus gallus)
atRA [nucleoplasm]
Developmental Biology (Homo sapiens)
Activation of HOX genes during differentiation (Homo sapiens)
Activation of anterior HOX genes in hindbrain development during early embryogenesis (Homo sapiens)
HOXA1 gene is transcribed (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
HOXA2 chromatin is activated (Homo sapiens)
atRA [nucleoplasm]
HOXA4 gene is transcribed (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
HOXB1 gene is transcribed (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
HOXB1 maintains activation of HOXB1 chromatin (Homo sapiens)
atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
HOXB2 chromatin is activated (Homo sapiens)
atRA [nucleoplasm]
HOXB4 gene is transcribed (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
HOXD1 chromatin is activated (Homo sapiens)
atRA [nucleoplasm]
HOXD3 chromatin is activated (Homo sapiens)
atRA [nucleoplasm]
HOXD4 gene is transcribed (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Retinoic acid activates HOXA1 chromatin (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,G:RXRA at active HOXA1 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Retinoic acid activates HOXA4 chromatin (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,B:RXRA at active HOXA4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Retinoic acid activates HOXB1 chromatin (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,G:RXRA at active HOXB1 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,G:atRA [nucleoplasm] (Homo sapiens)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Retinoic acid activates HOXB4 chromatin (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA,B:RXRA at active HOXB4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Retinoic acid activates HOXD4 chromatin (Homo sapiens)
atRA:RARA,B:RXRA at active HOXD4 chromatin [nucleoplasm] (Homo sapiens)
RXRA:RARA,B:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Transcriptional regulation of granulopoiesis (Homo sapiens)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Homo sapiens)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Homo sapiens)
atRA:RARA:RXRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
CEBPE gene expression is enhanced by CEBPA, SPI1 (PU.1), and retinoic acid (Homo sapiens)
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Homo sapiens)
atRA:RARA:RXRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Homo sapiens)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Homo sapiens)
NPM1 binds TFAP2A homodimer (Homo sapiens)
atRA [nucleoplasm]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine shuttle (Homo sapiens)
CPT1A transfers PALM to CAR (Homo sapiens)
RXRA:PPARD:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
Signaling by Retinoic Acid (Homo sapiens)
FABP5 dissociates from RXRA:PPARD:atRA (Homo sapiens)
RXRA:PPARD:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Homo sapiens)
FABP5:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Homo sapiens)
FABP5:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Homo sapiens)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Homo sapiens)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Homo sapiens)
FABP5:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Homo sapiens)
FABP5:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Homo sapiens)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Homo sapiens)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Homo sapiens)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Signaling by TGFB family members (Homo sapiens)
Signaling by TGFBR3 (Homo sapiens)
TGFBR3 expression (Homo sapiens)
Binding of ATRA to TGFBR3 gene promoter (Homo sapiens)
aTRA:TGFBR3 gene [nucleoplasm] (Homo sapiens)
atRA:RARA:RXRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
atRA:RARA:RXRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
TGFBR3 transcription (Homo sapiens)
aTRA:TGFBR3 gene [nucleoplasm] (Homo sapiens)
atRA:RARA:RXRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Homo sapiens)
atRA [nucleoplasm]
Developmental Biology (Mus musculus)
Transcriptional regulation of granulopoiesis (Mus musculus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Mus musculus)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Mus musculus)
atRA:RARA:RXRA [nucleoplasm] (Mus musculus)
RARA:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Mus musculus)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Mus musculus)
NPM1 binds TFAP2A homodimer (Mus musculus)
atRA [nucleoplasm]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Carnitine shuttle (Mus musculus)
CPT1A transfers PALM to CAR (Mus musculus)
RXRA:PPARD:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
Signaling by Retinoic Acid (Mus musculus)
FABP5 dissociates from RXRA:PPARD:atRA (Mus musculus)
RXRA:PPARD:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Mus musculus)
FABP5:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Mus musculus)
FABP5:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Mus musculus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Mus musculus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Mus musculus)
FABP5:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Mus musculus)
FABP5:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Mus musculus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Mus musculus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Mus musculus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Mus musculus)
atRA [nucleoplasm]
Developmental Biology (Rattus norvegicus)
Transcriptional regulation of granulopoiesis (Rattus norvegicus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Rattus norvegicus)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Rattus norvegicus)
atRA:RARA:RXRA [nucleoplasm] (Rattus norvegicus)
RARA:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Rattus norvegicus)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Rattus norvegicus)
NPM1 binds TFAP2A homodimer (Rattus norvegicus)
atRA [nucleoplasm]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Carnitine shuttle (Rattus norvegicus)
CPT1A transfers PALM to CAR (Rattus norvegicus)
RXRA:PPARD:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
Signaling by Retinoic Acid (Rattus norvegicus)
FABP5 dissociates from RXRA:PPARD:atRA (Rattus norvegicus)
RXRA:PPARD:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Rattus norvegicus)
FABP5:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Rattus norvegicus)
FABP5:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Rattus norvegicus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Rattus norvegicus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Rattus norvegicus)
FABP5:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Rattus norvegicus)
FABP5:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Rattus norvegicus)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Rattus norvegicus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Rattus norvegicus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Rattus norvegicus)
atRA [nucleoplasm]
Developmental Biology (Sus scrofa)
Transcriptional regulation of granulopoiesis (Sus scrofa)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Sus scrofa)
atRA [nucleoplasm]
CEBPE gene:RXRA:RARA:atRA [nucleoplasm] (Sus scrofa)
atRA:RARA:RXRA [nucleoplasm] (Sus scrofa)
RARA:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Sus scrofa)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Sus scrofa)
NPM1 binds TFAP2A homodimer (Sus scrofa)
atRA [nucleoplasm]
Metabolism (Sus scrofa)
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Carnitine shuttle (Sus scrofa)
CPT1A transfers PALM to CAR (Sus scrofa)
RXRA:PPARD:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
Signaling by Retinoic Acid (Sus scrofa)
FABP5 dissociates from RXRA:PPARD:atRA (Sus scrofa)
RXRA:PPARD:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Sus scrofa)
FABP5:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Sus scrofa)
FABP5:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
RAR:RXR binds SUMO-CRABP2:atRA (Sus scrofa)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Sus scrofa)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
SUMO-K102-CRABP2:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Sus scrofa)
FABP5:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Sus scrofa)
FABP5:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
SUMO-CRABP2 dissociates from atRA:RAR:RXR (Sus scrofa)
SUMO-CRABP2:atRA:RAR:RXR [nucleoplasm] (Sus scrofa)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
atRA:RAR:RXR [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Sus scrofa)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Sus scrofa)
atRA [nucleoplasm]
Gene expression (Transcription) (Xenopus tropicalis)
RNA Polymerase II Transcription (Xenopus tropicalis)
Generic Transcription Pathway (Xenopus tropicalis)
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors (Xenopus tropicalis)
TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation (Xenopus tropicalis)
NPM1 binds TFAP2A homodimer (Xenopus tropicalis)
atRA [nucleoplasm]
Signal Transduction (Xenopus tropicalis)
Signaling by Nuclear Receptors (Xenopus tropicalis)
Signaling by Retinoic Acid (Xenopus tropicalis)
FABP5 dissociates from RXRA:PPARD:atRA (Xenopus tropicalis)
RXRA:PPARD:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
FABP5:atRA translocates from cytosol to nucleoplasm (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
RXRA:PPARD binds FABP5:atRA (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
RXRA:PPARD:atRA:FABP5 [nucleoplasm] (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
SUMO-CRABP2:atRA translocates from cytosol to nucleus (Xenopus tropicalis)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Xenopus tropicalis)
atRA [nucleoplasm]
External Reference Information
External Reference
all-trans-retinoic acid [ChEBI:15367]
Participates
as a component of
atRA:RAR:RXR [nucleoplasm] (Danio rerio)
atRA:RAR:RXR [nucleoplasm] (Mus musculus)
atRA:RAR:RXR [nucleoplasm] (Caenorhabditis elegans)
atRA:RAR:RXR [nucleoplasm] (Drosophila melanogaster)
atRA:RAR:RXR [nucleoplasm] (Gallus gallus)
atRA:RAR:RXR [nucleoplasm] (Canis familiaris)
atRA:RAR:RXR [nucleoplasm] (Sus scrofa)
atRA:RAR:RXR [nucleoplasm] (Bos taurus)
atRA:RAR:RXR [nucleoplasm] (Rattus norvegicus)
atRA:RAR:RXR [nucleoplasm] (Homo sapiens)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Danio rerio)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Canis familiaris)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Drosophila melanogaster)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Rattus norvegicus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Gallus gallus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Bos taurus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Caenorhabditis elegans)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Sus scrofa)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Xenopus tropicalis)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Mus musculus)
SUMO-K102-CRABP2:atRA [nucleoplasm] (Homo sapiens)
RARA,B:atRA [nucleoplasm] (Homo sapiens)
Rara,b:atRA [nucleoplasm] (Mus musculus)
RARA,G:atRA [nucleoplasm] (Homo sapiens)
Rara,g:atRA [nucleoplasm] (Mus musculus)
RXRA:PPARD:atRA [nucleoplasm] (Homo sapiens)
RXRA:PPARD:atRA [nucleoplasm] (Gallus gallus)
RXRA:PPARD:atRA [nucleoplasm] (Mus musculus)
RXRA:PPARD:atRA [nucleoplasm] (Caenorhabditis elegans)
RXRA:PPARD:atRA [nucleoplasm] (Drosophila melanogaster)
RXRA:PPARD:atRA [nucleoplasm] (Sus scrofa)
RXRA:PPARD:atRA [nucleoplasm] (Rattus norvegicus)
RXRA:PPARD:atRA [nucleoplasm] (Canis familiaris)
RXRA:PPARD:atRA [nucleoplasm] (Bos taurus)
RXRA:PPARD:atRA [nucleoplasm] (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Homo sapiens)
FABP5:atRA [nucleoplasm] (Canis familiaris)
FABP5:atRA [nucleoplasm] (Xenopus tropicalis)
FABP5:atRA [nucleoplasm] (Sus scrofa)
FABP5:atRA [nucleoplasm] (Bos taurus)
FABP5:atRA [nucleoplasm] (Mus musculus)
FABP5:atRA [nucleoplasm] (Rattus norvegicus)
FABP5:atRA [nucleoplasm] (Gallus gallus)
FABP5:atRA [nucleoplasm] (Caenorhabditis elegans)
RARA:atRA [nucleoplasm] (Homo sapiens)
RARA:atRA [nucleoplasm] (Bos taurus)
RARA:atRA [nucleoplasm] (Danio rerio)
RARA:atRA [nucleoplasm] (Drosophila melanogaster)
RARA:atRA [nucleoplasm] (Mus musculus)
RARA:atRA [nucleoplasm] (Gallus gallus)
RARA:atRA [nucleoplasm] (Rattus norvegicus)
RARA:atRA [nucleoplasm] (Caenorhabditis elegans)
RARA:atRA [nucleoplasm] (Sus scrofa)
RARA:atRA [nucleoplasm] (Canis familiaris)
as an input of
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Caenorhabditis elegans)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Drosophila melanogaster)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Gallus gallus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Danio rerio)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Sus scrofa)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Bos taurus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Canis familiaris)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Rattus norvegicus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Mus musculus)
Retinoic acid activates HOXB4 chromatin (Homo sapiens)
Retinoic acid activates HOXB1 chromatin (Homo sapiens)
Retinoic acid activates Hoxb1 chromatin (Mus musculus)
Retinoic acid activates HOXA4 chromatin (Homo sapiens)
Retinoic acid activates Hoxa4 chromatin (Mus musculus)
Retinoic acid activates HOXA1 chromatin (Homo sapiens)
Retinoic acid activates Hoxa1 chromatin (Mus musculus)
All-trans retinoic acid binds RARA:RXRA at the promoter of the CEBPE gene (Homo sapiens)
This entity regulates
Positively
NPM1 binds TFAP2A homodimer
(Mus musculus)
HOXA2 chromatin is activated
(Homo sapiens)
NPM1 binds TFAP2A homodimer
(Drosophila melanogaster)
NPM1 binds TFAP2A homodimer
(Xenopus tropicalis)
NPM1 binds TFAP2A homodimer
(Homo sapiens)
HOXD3 chromatin is activated
(Homo sapiens)
NPM1 binds TFAP2A homodimer
(Gallus gallus)
NPM1 binds TFAP2A homodimer
(Sus scrofa)
NPM1 binds TFAP2A homodimer
(Rattus norvegicus)
HOXB2 chromatin is activated
(Homo sapiens)
NPM1 binds TFAP2A homodimer
(Bos taurus)
NPM1 binds TFAP2A homodimer
(Canis familiaris)
HOXD1 chromatin is activated
(Homo sapiens)
Other forms of this molecule
atRA [endoplasmic reticulum lumen]
atRA [cytosol]
atRA [extracellular region]
Cross References
Guide to Pharmacology - Ligands
2644
COMPOUND
C00777
HMDB Metabolite
HMDB0001852
ZINC
ZINC000012358651
© 2025
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![atRA [nucleoplasm] icon](/icon/R-ICO-013649.svg){kind=icon}
