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NAM [mitochondrial matrix]
Stable Identifier
R-ALL-5688274
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
nicotinamide
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Citric acid cycle (TCA cycle) (Bos taurus)
Maturation of TCA enzymes and regulation of TCA cycle (Bos taurus)
SIRT3 deacetylates AcK-IDH2 dimer (Bos taurus)
NAM [mitochondrial matrix]
Pyruvate metabolism (Bos taurus)
Regulation of pyruvate metabolism (Bos taurus)
Regulation of pyruvate dehydrogenase (PDH) complex (Bos taurus)
SIRT4 cleaves lipoyl from DLAT (Bos taurus)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Bos taurus)
Urea cycle (Bos taurus)
SIRT5 deglutarylates CPS1 (Bos taurus)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Bos taurus)
Mitochondrial biogenesis (Bos taurus)
Transcriptional activation of mitochondrial biogenesis (Bos taurus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Bos taurus)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Bos taurus)
NAM [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Pyruvate metabolism (Caenorhabditis elegans)
Regulation of pyruvate metabolism (Caenorhabditis elegans)
Regulation of pyruvate dehydrogenase (PDH) complex (Caenorhabditis elegans)
SIRT4 cleaves lipoyl from DLAT (Caenorhabditis elegans)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Caenorhabditis elegans)
Mitochondrial biogenesis (Caenorhabditis elegans)
Transcriptional activation of mitochondrial biogenesis (Caenorhabditis elegans)
SIRT4 transfers ADPRib to GLUD (Caenorhabditis elegans)
NAM [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Citric acid cycle (TCA cycle) (Canis familiaris)
Maturation of TCA enzymes and regulation of TCA cycle (Canis familiaris)
SIRT3 deacetylates AcK-IDH2 dimer (Canis familiaris)
NAM [mitochondrial matrix]
Pyruvate metabolism (Canis familiaris)
Regulation of pyruvate metabolism (Canis familiaris)
Regulation of pyruvate dehydrogenase (PDH) complex (Canis familiaris)
SIRT4 cleaves lipoyl from DLAT (Canis familiaris)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Canis familiaris)
Mitochondrial biogenesis (Canis familiaris)
Transcriptional activation of mitochondrial biogenesis (Canis familiaris)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Canis familiaris)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Canis familiaris)
NAM [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Citric acid cycle (TCA cycle) (Danio rerio)
Maturation of TCA enzymes and regulation of TCA cycle (Danio rerio)
SIRT3 deacetylates AcK-IDH2 dimer (Danio rerio)
NAM [mitochondrial matrix]
Pyruvate metabolism (Danio rerio)
Regulation of pyruvate metabolism (Danio rerio)
Regulation of pyruvate dehydrogenase (PDH) complex (Danio rerio)
SIRT4 cleaves lipoyl from DLAT (Danio rerio)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Danio rerio)
Mitochondrial biogenesis (Danio rerio)
Transcriptional activation of mitochondrial biogenesis (Danio rerio)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Danio rerio)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Danio rerio)
NAM [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Pyruvate metabolism (Drosophila melanogaster)
Regulation of pyruvate metabolism (Drosophila melanogaster)
Regulation of pyruvate dehydrogenase (PDH) complex (Drosophila melanogaster)
SIRT4 cleaves lipoyl from DLAT (Drosophila melanogaster)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Drosophila melanogaster)
Mitochondrial biogenesis (Drosophila melanogaster)
Transcriptional activation of mitochondrial biogenesis (Drosophila melanogaster)
SIRT4 transfers ADPRib to GLUD (Drosophila melanogaster)
NAM [mitochondrial matrix]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Citric acid cycle (TCA cycle) (Gallus gallus)
Maturation of TCA enzymes and regulation of TCA cycle (Gallus gallus)
SIRT3 deacetylates AcK-IDH2 dimer (Gallus gallus)
NAM [mitochondrial matrix]
Pyruvate metabolism (Gallus gallus)
Regulation of pyruvate metabolism (Gallus gallus)
Regulation of pyruvate dehydrogenase (PDH) complex (Gallus gallus)
SIRT4 cleaves lipoyl from DLAT (Gallus gallus)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Gallus gallus)
Urea cycle (Gallus gallus)
SIRT5 deglutarylates CPS1 (Gallus gallus)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Gallus gallus)
Mitochondrial biogenesis (Gallus gallus)
Transcriptional activation of mitochondrial biogenesis (Gallus gallus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Gallus gallus)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Gallus gallus)
NAM [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Citric acid cycle (TCA cycle) (Homo sapiens)
Maturation of TCA enzymes and regulation of TCA cycle (Homo sapiens)
SIRT3 deacetylates AcK-IDH2 dimer (Homo sapiens)
NAM [mitochondrial matrix]
Pyruvate metabolism (Homo sapiens)
Regulation of pyruvate metabolism (Homo sapiens)
Regulation of pyruvate dehydrogenase (PDH) complex (Homo sapiens)
SIRT4 cleaves lipoyl from DLAT (Homo sapiens)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Homo sapiens)
Urea cycle (Homo sapiens)
SIRT5 deglutarylates CPS1 (Homo sapiens)
NAM [mitochondrial matrix]
SIRT5 desuccinylates CPS1 (Homo sapiens)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Homo sapiens)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Homo sapiens)
NAM [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Citric acid cycle (TCA cycle) (Mus musculus)
Maturation of TCA enzymes and regulation of TCA cycle (Mus musculus)
SIRT3 deacetylates AcK-IDH2 dimer (Mus musculus)
NAM [mitochondrial matrix]
Pyruvate metabolism (Mus musculus)
Regulation of pyruvate metabolism (Mus musculus)
Regulation of pyruvate dehydrogenase (PDH) complex (Mus musculus)
SIRT4 cleaves lipoyl from DLAT (Mus musculus)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Mus musculus)
Urea cycle (Mus musculus)
SIRT5 deglutarylates CPS1 (Mus musculus)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Mus musculus)
Mitochondrial biogenesis (Mus musculus)
Transcriptional activation of mitochondrial biogenesis (Mus musculus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Mus musculus)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Mus musculus)
NAM [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Citric acid cycle (TCA cycle) (Rattus norvegicus)
Maturation of TCA enzymes and regulation of TCA cycle (Rattus norvegicus)
SIRT3 deacetylates AcK-IDH2 dimer (Rattus norvegicus)
NAM [mitochondrial matrix]
Pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate metabolism (Rattus norvegicus)
Regulation of pyruvate dehydrogenase (PDH) complex (Rattus norvegicus)
SIRT4 cleaves lipoyl from DLAT (Rattus norvegicus)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Urea cycle (Rattus norvegicus)
SIRT5 deglutarylates CPS1 (Rattus norvegicus)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Rattus norvegicus)
Mitochondrial biogenesis (Rattus norvegicus)
Transcriptional activation of mitochondrial biogenesis (Rattus norvegicus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Rattus norvegicus)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Rattus norvegicus)
NAM [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Citric acid cycle (TCA cycle) (Sus scrofa)
Maturation of TCA enzymes and regulation of TCA cycle (Sus scrofa)
SIRT3 deacetylates AcK-IDH2 dimer (Sus scrofa)
NAM [mitochondrial matrix]
Pyruvate metabolism (Sus scrofa)
Regulation of pyruvate metabolism (Sus scrofa)
Regulation of pyruvate dehydrogenase (PDH) complex (Sus scrofa)
SIRT4 cleaves lipoyl from DLAT (Sus scrofa)
NAM [mitochondrial matrix]
Metabolism of amino acids and derivatives (Sus scrofa)
Urea cycle (Sus scrofa)
SIRT5 deglutarylates CPS1 (Sus scrofa)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Sus scrofa)
Mitochondrial biogenesis (Sus scrofa)
Transcriptional activation of mitochondrial biogenesis (Sus scrofa)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Sus scrofa)
NAM [mitochondrial matrix]
SIRT4 transfers ADPRib to GLUD (Sus scrofa)
NAM [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Pyruvate metabolism (Xenopus tropicalis)
Regulation of pyruvate metabolism (Xenopus tropicalis)
Regulation of pyruvate dehydrogenase (PDH) complex (Xenopus tropicalis)
SIRT4 cleaves lipoyl from DLAT (Xenopus tropicalis)
NAM [mitochondrial matrix]
Organelle biogenesis and maintenance (Xenopus tropicalis)
Mitochondrial biogenesis (Xenopus tropicalis)
Transcriptional activation of mitochondrial biogenesis (Xenopus tropicalis)
SIRT4 transfers ADPRib to GLUD (Xenopus tropicalis)
NAM [mitochondrial matrix]
External Reference Information
External Reference
nicotinamide [ChEBI:17154]
Participates
as an output of
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Gallus gallus)
SIRT5 deglutarylates CPS1 (Homo sapiens)
SIRT5 deglutarylates CPS1 (Mus musculus)
SIRT5 deglutarylates CPS1 (Rattus norvegicus)
SIRT5 deglutarylates CPS1 (Bos taurus)
SIRT5 deglutarylates CPS1 (Sus scrofa)
SIRT5 deglutarylates CPS1 (Gallus gallus)
SIRT5 desuccinylates CPS1 (Homo sapiens)
Sirt5 desuccinylates Cps1 (Mus musculus)
SIRT3 deacetylates AcK-IDH2 dimer (Homo sapiens)
SIRT3 deacetylates AcK-IDH2 dimer (Mus musculus)
SIRT3 deacetylates AcK-IDH2 dimer (Rattus norvegicus)
SIRT3 deacetylates AcK-IDH2 dimer (Canis familiaris)
SIRT3 deacetylates AcK-IDH2 dimer (Bos taurus)
SIRT3 deacetylates AcK-IDH2 dimer (Sus scrofa)
SIRT3 deacetylates AcK-IDH2 dimer (Danio rerio)
SIRT3 deacetylates AcK-IDH2 dimer (Gallus gallus)
SIRT4 cleaves lipoyl from DLAT (Rattus norvegicus)
SIRT4 cleaves lipoyl from DLAT (Homo sapiens)
SIRT4 cleaves lipoyl from DLAT (Mus musculus)
SIRT4 cleaves lipoyl from DLAT (Canis familiaris)
SIRT4 cleaves lipoyl from DLAT (Bos taurus)
SIRT4 cleaves lipoyl from DLAT (Sus scrofa)
SIRT4 cleaves lipoyl from DLAT (Danio rerio)
SIRT4 cleaves lipoyl from DLAT (Xenopus tropicalis)
SIRT4 cleaves lipoyl from DLAT (Gallus gallus)
SIRT4 cleaves lipoyl from DLAT (Drosophila melanogaster)
SIRT4 cleaves lipoyl from DLAT (Caenorhabditis elegans)
SIRT4 transfers ADPRib to GLUD (Homo sapiens)
SIRT4 transfers ADPRib to GLUD (Mus musculus)
SIRT4 transfers ADPRib to GLUD (Rattus norvegicus)
SIRT4 transfers ADPRib to GLUD (Canis familiaris)
SIRT4 transfers ADPRib to GLUD (Bos taurus)
SIRT4 transfers ADPRib to GLUD (Sus scrofa)
SIRT4 transfers ADPRib to GLUD (Danio rerio)
SIRT4 transfers ADPRib to GLUD (Xenopus tropicalis)
SIRT4 transfers ADPRib to GLUD (Gallus gallus)
SIRT4 transfers ADPRib to GLUD (Drosophila melanogaster)
SIRT4 transfers ADPRib to GLUD (Caenorhabditis elegans)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Homo sapiens)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Mus musculus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Rattus norvegicus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Canis familiaris)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Bos taurus)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Sus scrofa)
SIRT3 deacetylates ACCS2, GLUD, IDH2, SOD2 (Danio rerio)
Other forms of this molecule
NAM [mitochondrial intermembrane space]
NAM [extracellular region]
NAM [cytosol]
NAM [nucleoplasm]
Cross References
COMPOUND
C00153
HMDB Metabolite
HMDB0001406
ZINC
ZINC000000005878
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![NAM [mitochondrial matrix] icon](/icon/R-ICO-013078.svg){kind=icon}
