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ISV-CoA [mitochondrial matrix]
Stable Identifier
R-ALL-70715
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
3-methylbutanoyl-CoA, isovaleryl-CoA
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Branched-chain amino acid catabolism (Bos taurus)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Bos taurus)
DBT transfers BCAA to CoA (Bos taurus)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Bos taurus)
ISV-CoA [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Branched-chain amino acid catabolism (Caenorhabditis elegans)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Caenorhabditis elegans)
DBT transfers BCAA to CoA (Caenorhabditis elegans)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Caenorhabditis elegans)
ISV-CoA [mitochondrial matrix]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Branched-chain amino acid catabolism (Canis familiaris)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Canis familiaris)
DBT transfers BCAA to CoA (Canis familiaris)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Canis familiaris)
ISV-CoA [mitochondrial matrix]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Branched-chain amino acid catabolism (Danio rerio)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Danio rerio)
DBT transfers BCAA to CoA (Danio rerio)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Danio rerio)
ISV-CoA [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Branched-chain amino acid catabolism (Dictyostelium discoideum)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Dictyostelium discoideum)
DBT transfers BCAA to CoA (Dictyostelium discoideum)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Dictyostelium discoideum)
ISV-CoA [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Branched-chain amino acid catabolism (Drosophila melanogaster)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Drosophila melanogaster)
DBT transfers BCAA to CoA (Drosophila melanogaster)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Drosophila melanogaster)
ISV-CoA [mitochondrial matrix]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Branched-chain amino acid catabolism (Gallus gallus)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Gallus gallus)
DBT transfers BCAA to CoA (Gallus gallus)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Gallus gallus)
ISV-CoA [mitochondrial matrix]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of branched-chain amino acid catabolism (Homo sapiens)
Isovaleric acidemia (Homo sapiens)
IVD mutants don't synthesize beta-methylcrotonyl-CoA (Homo sapiens)
ISV-CoA [mitochondrial matrix]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Branched-chain amino acid catabolism (Homo sapiens)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Homo sapiens)
DBT transfers BCAA to CoA (Homo sapiens)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Homo sapiens)
ISV-CoA [mitochondrial matrix]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Branched-chain amino acid catabolism (Mus musculus)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Mus musculus)
DBT transfers BCAA to CoA (Mus musculus)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Mus musculus)
ISV-CoA [mitochondrial matrix]
Metabolism (Plasmodium falciparum)
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Branched-chain amino acid catabolism (Plasmodium falciparum)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Plasmodium falciparum)
DBT transfers BCAA to CoA (Plasmodium falciparum)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Branched-chain amino acid catabolism (Rattus norvegicus)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Rattus norvegicus)
DBT transfers BCAA to CoA (Rattus norvegicus)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Rattus norvegicus)
ISV-CoA [mitochondrial matrix]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Branched-chain amino acid catabolism (Sus scrofa)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Sus scrofa)
DBT transfers BCAA to CoA (Sus scrofa)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Sus scrofa)
ISV-CoA [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Branched-chain amino acid catabolism (Xenopus tropicalis)
BCKDH synthesizes BCAA-CoA from KIC, KMVA, KIV (Xenopus tropicalis)
DBT transfers BCAA to CoA (Xenopus tropicalis)
BCAA-CoAs [mitochondrial matrix]
ISV-CoA [mitochondrial matrix]
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Xenopus tropicalis)
ISV-CoA [mitochondrial matrix]
External Reference Information
External Reference
isovaleryl-CoA(4-) [ChEBI:57345]
Participates
as an input of
IVD mutants don't synthesize beta-methylcrotonyl-CoA (Homo sapiens)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Dictyostelium discoideum)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Caenorhabditis elegans)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Drosophila melanogaster)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Gallus gallus)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Xenopus tropicalis)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Danio rerio)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Sus scrofa)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Bos taurus)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Canis familiaris)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Mus musculus)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Homo sapiens)
isovaleryl-CoA + FAD => beta-methylcrotonyl-CoA + FADH2 (Rattus norvegicus)
as a member of
BCAA-CoAs [mitochondrial matrix]
Cross References
COMPOUND
C02939
ZINC
000008551494
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