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About
What is Reactome ?
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Team
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heme [cytosol]
Stable Identifier
R-ALL-71185
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
ferroheme b(2-), ferroheme b, heme (ferrous)
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Cytoprotection by HMOX1 (Bos taurus)
HMOX1 dimer, HMOX2 cleave heme (Bos taurus)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Bos taurus)
NOX2 generates superoxide from oxygen (Bos taurus)
NOX2 complex [phagocytic vesicle membrane] (Bos taurus)
Cytochrome b-245 [phagocytic vesicle membrane] (Bos taurus)
heme [cytosol]
Heme signaling (Bos taurus)
PGRMC2 binds Hemes (Bos taurus)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Bos taurus)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Bos taurus)
XPO1:BACH1:Hemes [cytosol] (Bos taurus)
BACH1:Hemes [cytosol] (Bos taurus)
Hemes [cytosol]
heme [cytosol]
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Sulfur amino acid metabolism (Bos taurus)
Cysteine formation from homocysteine (Bos taurus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Bos taurus)
PXLP-K119-CBS tetramer [cytosol] (Bos taurus)
heme [cytosol]
Tryptophan catabolism (Bos taurus)
IDO1 dioxygenates L-Trp to NFK (Bos taurus)
IDO1 [cytosol] (Bos taurus)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Bos taurus)
IDO2 [cytosol] (Bos taurus)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Bos taurus)
TDO2 tetramer [cytosol] (Bos taurus)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Bos taurus)
NOSIP mediated eNOS trafficking (Bos taurus)
eNOS binds NOSIP (Bos taurus)
eNOS:NOSIP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Bos taurus)
eNOS:NOSIP [Golgi membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
NOSTRIN mediated eNOS trafficking (Bos taurus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Bos taurus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Bos taurus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Bos taurus)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS activation (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
CYGB binds O2 (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB dioxygenates NO (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Bos taurus)
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Bos taurus)
myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Bos taurus)
heme [cytosol]
depalmitoylation of eNOS (Bos taurus)
myristoylated eNOS dimer [cytosol] (Bos taurus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS associates with Caveolin-1 (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Metabolism of porphyrins (Bos taurus)
Heme biosynthesis (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Bos taurus)
heme [cytosol]
Heme degradation (Bos taurus)
HMOX1 dimer, HMOX2 cleave heme (Bos taurus)
heme [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
BH2 binding can lead to eNOS uncoupling (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
VEGFR2 mediated vascular permeability (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Bos taurus)
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases Activate NADPH Oxidases (Bos taurus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Bos taurus)
NOX2 complex:RAC1:GTP [plasma membrane] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
RHO GTPase cycle (Bos taurus)
RAC1 GTPase cycle (Bos taurus)
RAC1 binds effectors at the plasma membrane (Bos taurus)
RAC1 effectors [cytosol] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Bos taurus)
RAC1 effectors [cytosol] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
RAC3 GTPase cycle (Bos taurus)
RAC3 binds effectors at the plasma membrane (Bos taurus)
RAC3 effectors [cytosol] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Bos taurus)
RAC3 effectors [cytosol] (Bos taurus)
NOX2 complex [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Bos taurus)
heme [cytosol]
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
Mitochondrial ABC transporters (Bos taurus)
ABC7, mABC1 and mABC2 mediate heme transport (Bos taurus)
heme [cytosol]
Intracellular oxygen transport (Bos taurus)
CYGB binds O2 (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB:O2 dissociates (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Bos taurus)
CYGB dimer [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Bos taurus)
heme [cytosol]
Myoglobin binds oxygen (Bos taurus)
MB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Bos taurus)
MB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Myoglobin:oxygen dissociates (Bos taurus)
MB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Bos taurus)
MB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Neuroglobin binds oxygen (Bos taurus)
NGB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Bos taurus)
NGB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Neuroglobin:oxygen dissociates (Bos taurus)
NGB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Bos taurus)
NGB:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Iron uptake and transport (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Bos taurus)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Bos taurus)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Bos taurus)
Erythrocytes take up carbon dioxide and release oxygen (Bos taurus)
CYB5Rs reduce MetHb to HbA (Bos taurus)
HbA [cytosol] (Bos taurus)
Hemoglobin alpha:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Bos taurus)
OxyHbA [cytosol] (Bos taurus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Bos taurus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Bos taurus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Bos taurus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Bos taurus)
Hemoglobin A binds O2, releasing H+ and CO2 (Bos taurus)
OxyHbA [cytosol] (Bos taurus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Bos taurus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Bos taurus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Bos taurus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Bos taurus)
heme [cytosol]
Cellular responses to stimuli (Caenorhabditis elegans)
Cellular responses to stress (Caenorhabditis elegans)
Heme signaling (Caenorhabditis elegans)
PGRMC2 binds Hemes (Caenorhabditis elegans)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Caenorhabditis elegans)
Hemes [cytosol]
heme [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Sulfur amino acid metabolism (Caenorhabditis elegans)
Cysteine formation from homocysteine (Caenorhabditis elegans)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Caenorhabditis elegans)
PXLP-K119-CBS tetramer [cytosol] (Caenorhabditis elegans)
heme [cytosol]
Tryptophan catabolism (Caenorhabditis elegans)
TDO tetramer dioxygenates L-Trp to NFK (Caenorhabditis elegans)
TDO2 tetramer [cytosol] (Caenorhabditis elegans)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Caenorhabditis elegans)
eNOS activation (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
eNOS:CaM:HSP90 [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
CYGB binds O2 (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB dioxygenates NO (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
Metabolism of porphyrins (Caenorhabditis elegans)
Heme biosynthesis (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Caenorhabditis elegans)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Caenorhabditis elegans)
heme [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Caenorhabditis elegans)
BH2 binding can lead to eNOS uncoupling (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
eNOS:CaM:HSP90 [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
heme [cytosol]
Transport of small molecules (Caenorhabditis elegans)
ABC-family proteins mediated transport (Caenorhabditis elegans)
Mitochondrial ABC transporters (Caenorhabditis elegans)
ABC7, mABC1 and mABC2 mediate heme transport (Caenorhabditis elegans)
heme [cytosol]
Intracellular oxygen transport (Caenorhabditis elegans)
CYGB binds O2 (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB:O2 dissociates (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Caenorhabditis elegans)
CYGB dimer [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Caenorhabditis elegans)
heme [cytosol]
Neuroglobin binds oxygen (Caenorhabditis elegans)
NGB:ferroheme b [cytosol] (Caenorhabditis elegans)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Caenorhabditis elegans)
NGB:ferroheme b [cytosol] (Caenorhabditis elegans)
heme [cytosol]
Neuroglobin:oxygen dissociates (Caenorhabditis elegans)
NGB:ferroheme b [cytosol] (Caenorhabditis elegans)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Caenorhabditis elegans)
NGB:ferroheme b [cytosol] (Caenorhabditis elegans)
heme [cytosol]
Iron uptake and transport (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Caenorhabditis elegans)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Caenorhabditis elegans)
Hemes [cytosol]
heme [cytosol]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
HMOX1 dimer, HMOX2 cleave heme (Canis familiaris)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Canis familiaris)
NOX2 generates superoxide from oxygen (Canis familiaris)
NOX2 complex [phagocytic vesicle membrane] (Canis familiaris)
Cytochrome b-245 [phagocytic vesicle membrane] (Canis familiaris)
heme [cytosol]
Heme signaling (Canis familiaris)
PGRMC2 binds Hemes (Canis familiaris)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Canis familiaris)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Canis familiaris)
XPO1:BACH1:Hemes [cytosol] (Canis familiaris)
BACH1:Hemes [cytosol] (Canis familiaris)
Hemes [cytosol]
heme [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Sulfur amino acid metabolism (Canis familiaris)
Cysteine formation from homocysteine (Canis familiaris)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Canis familiaris)
PXLP-K119-CBS tetramer [cytosol] (Canis familiaris)
heme [cytosol]
Tryptophan catabolism (Canis familiaris)
IDO1 dioxygenates L-Trp to NFK (Canis familiaris)
IDO1 [cytosol] (Canis familiaris)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Canis familiaris)
IDO2 [cytosol] (Canis familiaris)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Canis familiaris)
TDO2 tetramer [cytosol] (Canis familiaris)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Canis familiaris)
NOSTRIN mediated eNOS trafficking (Canis familiaris)
NOSTRIN mediated translocation of eNOS from plasma membrane (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Canis familiaris)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Canis familiaris)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
heme [cytosol]
eNOS activation (Canis familiaris)
CYGB binds O2 (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB dioxygenates NO (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
Metabolism of porphyrins (Canis familiaris)
Heme biosynthesis (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Canis familiaris)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Canis familiaris)
heme [cytosol]
Heme degradation (Canis familiaris)
HMOX1 dimer, HMOX2 cleave heme (Canis familiaris)
heme [cytosol]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by VEGF (Canis familiaris)
VEGFA-VEGFR2 Pathway (Canis familiaris)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)
NOX2 complex:RAC1:GTP [plasma membrane] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Canis familiaris)
Signaling by Rho GTPases (Canis familiaris)
RHO GTPase Effectors (Canis familiaris)
RHO GTPases Activate NADPH Oxidases (Canis familiaris)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Canis familiaris)
NOX2 complex:RAC1:GTP [plasma membrane] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
RHO GTPase cycle (Canis familiaris)
RAC1 GTPase cycle (Canis familiaris)
RAC1 binds effectors at the plasma membrane (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Canis familiaris)
RAC1 effectors [cytosol] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
RAC3 GTPase cycle (Canis familiaris)
RAC3 binds effectors at the plasma membrane (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Canis familiaris)
RAC3 effectors [cytosol] (Canis familiaris)
NOX2 complex [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
heme [cytosol]
Transport of small molecules (Canis familiaris)
ABC-family proteins mediated transport (Canis familiaris)
Mitochondrial ABC transporters (Canis familiaris)
ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)
heme [cytosol]
Intracellular oxygen transport (Canis familiaris)
CYGB binds O2 (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB:O2 dissociates (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Canis familiaris)
CYGB dimer [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Canis familiaris)
heme [cytosol]
Myoglobin binds oxygen (Canis familiaris)
MB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Canis familiaris)
MB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Myoglobin:oxygen dissociates (Canis familiaris)
MB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Canis familiaris)
MB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Neuroglobin binds oxygen (Canis familiaris)
NGB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Canis familiaris)
NGB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Neuroglobin:oxygen dissociates (Canis familiaris)
NGB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Canis familiaris)
NGB:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Iron uptake and transport (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Canis familiaris)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Canis familiaris)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Canis familiaris)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Canis familiaris)
Erythrocytes take up carbon dioxide and release oxygen (Canis familiaris)
CYB5Rs reduce MetHb to HbA (Canis familiaris)
HbA [cytosol] (Canis familiaris)
Hemoglobin alpha:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Canis familiaris)
OxyHbA [cytosol] (Canis familiaris)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Canis familiaris)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Canis familiaris)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Canis familiaris)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Canis familiaris)
Hemoglobin A binds O2, releasing H+ and CO2 (Canis familiaris)
OxyHbA [cytosol] (Canis familiaris)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Canis familiaris)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Canis familiaris)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Canis familiaris)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Canis familiaris)
heme [cytosol]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Cytoprotection by HMOX1 (Danio rerio)
HMOX1 dimer, HMOX2 cleave heme (Danio rerio)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Danio rerio)
NOX2 generates superoxide from oxygen (Danio rerio)
NOX2 complex [phagocytic vesicle membrane] (Danio rerio)
Cytochrome b-245 [phagocytic vesicle membrane] (Danio rerio)
heme [cytosol]
Heme signaling (Danio rerio)
PGRMC2 binds Hemes (Danio rerio)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Danio rerio)
Hemes [cytosol]
heme [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Sulfur amino acid metabolism (Danio rerio)
Cysteine formation from homocysteine (Danio rerio)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Danio rerio)
PXLP-K119-CBS tetramer [cytosol] (Danio rerio)
heme [cytosol]
Tryptophan catabolism (Danio rerio)
IDO2 dioxygenates L-Trp to NFK (Danio rerio)
IDO2 [cytosol] (Danio rerio)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Danio rerio)
TDO2 tetramer [cytosol] (Danio rerio)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Danio rerio)
NOSTRIN mediated eNOS trafficking (Danio rerio)
NOSTRIN mediated translocation of eNOS from plasma membrane (Danio rerio)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Danio rerio)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Danio rerio)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Danio rerio)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
heme [cytosol]
eNOS activation (Danio rerio)
CYGB binds O2 (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB dioxygenates NO (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
Metabolism of porphyrins (Danio rerio)
Heme degradation (Danio rerio)
HMOX1 dimer, HMOX2 cleave heme (Danio rerio)
heme [cytosol]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by VEGF (Danio rerio)
VEGFA-VEGFR2 Pathway (Danio rerio)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Danio rerio)
Signaling by Rho GTPases (Danio rerio)
RHO GTPase Effectors (Danio rerio)
RHO GTPases Activate NADPH Oxidases (Danio rerio)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Danio rerio)
NOX2 complex:RAC1:GTP [plasma membrane] (Danio rerio)
NOX2 complex [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Danio rerio)
heme [cytosol]
Transport of small molecules (Danio rerio)
ABC-family proteins mediated transport (Danio rerio)
Mitochondrial ABC transporters (Danio rerio)
ABC7, mABC1 and mABC2 mediate heme transport (Danio rerio)
heme [cytosol]
Intracellular oxygen transport (Danio rerio)
CYGB binds O2 (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB:O2 dissociates (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Danio rerio)
CYGB dimer [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Danio rerio)
heme [cytosol]
Myoglobin binds oxygen (Danio rerio)
MB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Danio rerio)
MB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Myoglobin:oxygen dissociates (Danio rerio)
MB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Danio rerio)
MB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Neuroglobin binds oxygen (Danio rerio)
NGB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Danio rerio)
NGB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Neuroglobin:oxygen dissociates (Danio rerio)
NGB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Danio rerio)
NGB:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Iron uptake and transport (Danio rerio)
HMOX1 dimer, HMOX2 cleave heme (Danio rerio)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Danio rerio)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Danio rerio)
Erythrocytes take up carbon dioxide and release oxygen (Danio rerio)
CYB5Rs reduce MetHb to HbA (Danio rerio)
HbA [cytosol] (Danio rerio)
Hemoglobin alpha:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Danio rerio)
OxyHbA [cytosol] (Danio rerio)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Danio rerio)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Danio rerio)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Danio rerio)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Danio rerio)
Hemoglobin A binds O2, releasing H+ and CO2 (Danio rerio)
OxyHbA [cytosol] (Danio rerio)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Danio rerio)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Danio rerio)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Danio rerio)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Danio rerio)
heme [cytosol]
Cellular responses to stimuli (Dictyostelium discoideum)
Cellular responses to stress (Dictyostelium discoideum)
Heme signaling (Dictyostelium discoideum)
PGRMC2 binds Hemes (Dictyostelium discoideum)
Hemes [cytosol]
heme [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Sulfur amino acid metabolism (Dictyostelium discoideum)
Cysteine formation from homocysteine (Dictyostelium discoideum)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Dictyostelium discoideum)
PXLP-K119-CBS tetramer [cytosol] (Dictyostelium discoideum)
heme [cytosol]
Tryptophan catabolism (Dictyostelium discoideum)
TDO tetramer dioxygenates L-Trp to NFK (Dictyostelium discoideum)
TDO2 tetramer [cytosol] (Dictyostelium discoideum)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Dictyostelium discoideum)
NOSIP mediated eNOS trafficking (Dictyostelium discoideum)
eNOS binds NOSIP (Dictyostelium discoideum)
eNOS:NOSIP [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Dictyostelium discoideum)
eNOS:NOSIP [Golgi membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS activation (Dictyostelium discoideum)
AKT1 binds eNOS complex via HSP90 (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Dictyostelium discoideum)
myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
heme [cytosol]
depalmitoylation of eNOS (Dictyostelium discoideum)
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
Metabolism of porphyrins (Dictyostelium discoideum)
Heme biosynthesis (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
heme [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of cofactors (Dictyostelium discoideum)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Dictyostelium discoideum)
BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated vascular permeability (Dictyostelium discoideum)
AKT1 binds eNOS complex via HSP90 (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
heme [cytosol]
Transport of small molecules (Dictyostelium discoideum)
ABC-family proteins mediated transport (Dictyostelium discoideum)
Mitochondrial ABC transporters (Dictyostelium discoideum)
ABC7, mABC1 and mABC2 mediate heme transport (Dictyostelium discoideum)
heme [cytosol]
Iron uptake and transport (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
heme [cytosol]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Cytoprotection by HMOX1 (Drosophila melanogaster)
HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)
heme [cytosol]
Heme signaling (Drosophila melanogaster)
PGRMC2 binds Hemes (Drosophila melanogaster)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Drosophila melanogaster)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Drosophila melanogaster)
XPO1:BACH1:Hemes [cytosol] (Drosophila melanogaster)
BACH1:Hemes [cytosol] (Drosophila melanogaster)
Hemes [cytosol]
heme [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Sulfur amino acid metabolism (Drosophila melanogaster)
Cysteine formation from homocysteine (Drosophila melanogaster)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Drosophila melanogaster)
PXLP-K119-CBS tetramer [cytosol] (Drosophila melanogaster)
heme [cytosol]
Tryptophan catabolism (Drosophila melanogaster)
TDO tetramer dioxygenates L-Trp to NFK (Drosophila melanogaster)
TDO2 tetramer [cytosol] (Drosophila melanogaster)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
NOSIP mediated eNOS trafficking (Drosophila melanogaster)
eNOS binds NOSIP (Drosophila melanogaster)
eNOS:NOSIP [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Drosophila melanogaster)
eNOS:NOSIP [Golgi membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS activation (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Drosophila melanogaster)
myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
heme [cytosol]
depalmitoylation of eNOS (Drosophila melanogaster)
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
Metabolism of porphyrins (Drosophila melanogaster)
Heme biosynthesis (Drosophila melanogaster)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Drosophila melanogaster)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Drosophila melanogaster)
heme [cytosol]
Heme degradation (Drosophila melanogaster)
HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)
heme [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Drosophila melanogaster)
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
heme [cytosol]
Transport of small molecules (Drosophila melanogaster)
ABC-family proteins mediated transport (Drosophila melanogaster)
Mitochondrial ABC transporters (Drosophila melanogaster)
ABC7, mABC1 and mABC2 mediate heme transport (Drosophila melanogaster)
heme [cytosol]
Iron uptake and transport (Drosophila melanogaster)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Drosophila melanogaster)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Drosophila melanogaster)
Hemes [cytosol]
heme [cytosol]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Cytoprotection by HMOX1 (Gallus gallus)
HMOX1 dimer, HMOX2 cleave heme (Gallus gallus)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Gallus gallus)
NOX2 generates superoxide from oxygen (Gallus gallus)
NOX2 complex [phagocytic vesicle membrane] (Gallus gallus)
Cytochrome b-245 [phagocytic vesicle membrane] (Gallus gallus)
heme [cytosol]
Heme signaling (Gallus gallus)
PGRMC2 binds Hemes (Gallus gallus)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Gallus gallus)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Gallus gallus)
XPO1:BACH1:Hemes [cytosol] (Gallus gallus)
BACH1:Hemes [cytosol] (Gallus gallus)
Hemes [cytosol]
heme [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Sulfur amino acid metabolism (Gallus gallus)
Cysteine formation from homocysteine (Gallus gallus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Gallus gallus)
PXLP-K119-CBS tetramer [cytosol] (Gallus gallus)
heme [cytosol]
Tryptophan catabolism (Gallus gallus)
IDO2 dioxygenates L-Trp to NFK (Gallus gallus)
IDO2 [cytosol] (Gallus gallus)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Gallus gallus)
TDO2 tetramer [cytosol] (Gallus gallus)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Gallus gallus)
NOSTRIN mediated eNOS trafficking (Gallus gallus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Gallus gallus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Gallus gallus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Gallus gallus)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS activation (Gallus gallus)
AKT1 binds eNOS complex via HSP90 (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
AKT1 phosphorylates eNOS (Gallus gallus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
CYGB binds O2 (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB dioxygenates NO (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Gallus gallus)
myristoylated eNOS dimer [Golgi membrane] (Gallus gallus)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Gallus gallus)
heme [cytosol]
depalmitoylation of eNOS (Gallus gallus)
myristoylated eNOS dimer [cytosol] (Gallus gallus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS associates with Caveolin-1 (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Metabolism of porphyrins (Gallus gallus)
Heme biosynthesis (Gallus gallus)
FLVCR1-1 transports heme from cytosol to extracellular region (Gallus gallus)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Gallus gallus)
heme [cytosol]
Heme degradation (Gallus gallus)
HMOX1 dimer, HMOX2 cleave heme (Gallus gallus)
heme [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of cofactors (Gallus gallus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Gallus gallus)
BH2 binding can lead to eNOS uncoupling (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
VEGFR2 mediated vascular permeability (Gallus gallus)
AKT1 binds eNOS complex via HSP90 (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
AKT1 phosphorylates eNOS (Gallus gallus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Gallus gallus)
Signaling by Rho GTPases (Gallus gallus)
RHO GTPase Effectors (Gallus gallus)
RHO GTPases Activate NADPH Oxidases (Gallus gallus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Gallus gallus)
NOX2 complex:RAC1:GTP [plasma membrane] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
RHO GTPase cycle (Gallus gallus)
RAC1 GTPase cycle (Gallus gallus)
RAC1 binds effectors at the plasma membrane (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Gallus gallus)
RAC1 effectors [cytosol] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
RAC3 GTPase cycle (Gallus gallus)
RAC3 binds effectors at the plasma membrane (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Gallus gallus)
RAC3 effectors [cytosol] (Gallus gallus)
NOX2 complex [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
heme [cytosol]
Transport of small molecules (Gallus gallus)
ABC-family proteins mediated transport (Gallus gallus)
Mitochondrial ABC transporters (Gallus gallus)
ABC7, mABC1 and mABC2 mediate heme transport (Gallus gallus)
heme [cytosol]
Intracellular oxygen transport (Gallus gallus)
CYGB binds O2 (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB:O2 dissociates (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Gallus gallus)
CYGB dimer [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Gallus gallus)
heme [cytosol]
Myoglobin binds oxygen (Gallus gallus)
MB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Gallus gallus)
MB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Myoglobin:oxygen dissociates (Gallus gallus)
MB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Gallus gallus)
MB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Neuroglobin binds oxygen (Gallus gallus)
NGB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Gallus gallus)
NGB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Neuroglobin:oxygen dissociates (Gallus gallus)
NGB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Gallus gallus)
NGB:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Iron uptake and transport (Gallus gallus)
FLVCR1-1 transports heme from cytosol to extracellular region (Gallus gallus)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Gallus gallus)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Gallus gallus)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Gallus gallus)
Erythrocytes take up carbon dioxide and release oxygen (Gallus gallus)
CYB5Rs reduce MetHb to HbA (Gallus gallus)
HbA [cytosol] (Gallus gallus)
Hemoglobin alpha:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Gallus gallus)
OxyHbA [cytosol] (Gallus gallus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Gallus gallus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Gallus gallus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Gallus gallus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Gallus gallus)
Hemoglobin A binds O2, releasing H+ and CO2 (Gallus gallus)
OxyHbA [cytosol] (Gallus gallus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Gallus gallus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Gallus gallus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Gallus gallus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Gallus gallus)
heme [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
HMOX1 dimer, HMOX2 cleave heme (Homo sapiens)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Homo sapiens)
NOX2 generates superoxide from oxygen (Homo sapiens)
NOX2 complex [phagocytic vesicle membrane] (Homo sapiens)
Cytochrome b-245 [phagocytic vesicle membrane] (Homo sapiens)
heme [cytosol]
Heme signaling (Homo sapiens)
PGRMC2 binds Hemes (Homo sapiens)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Homo sapiens)
XPO1:BACH1:Hemes [cytosol] (Homo sapiens)
BACH1:Hemes [cytosol] (Homo sapiens)
Hemes [cytosol]
heme [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Infection with Mycobacterium tuberculosis (Homo sapiens)
Latent infection - Other responses of Mtb to phagocytosis (Homo sapiens)
Mtb iron assimilation by chelation (Homo sapiens)
BfrA stores iron (Homo sapiens)
BfrA complex [cytosol] (Mycobacterium tuberculosis)
BfrA dimer [cytosol] (Mycobacterium tuberculosis)
heme [cytosol]
Tolerance by Mtb to nitric oxide produced by macrophages (Homo sapiens)
Nitric oxide is oxidized to nitrate (Homo sapiens)
GlbN:Heme dimer [cytosol] (Mycobacterium tuberculosis)
heme [cytosol]
Tolerance of reactive oxygen produced by macrophages (Homo sapiens)
KatG reduces H2O2 (Homo sapiens)
KatG dimer [cytosol] (Mycobacterium tuberculosis)
heme [cytosol]
Viral Infection Pathways (Homo sapiens)
SARS-CoV Infections (Homo sapiens)
SARS-CoV-2 Infection (Homo sapiens)
SARS-CoV-2-host interactions (Homo sapiens)
SARS-CoV-2 targets host intracellular signalling and regulatory pathways (Homo sapiens)
N binds to heme (Homo sapiens)
heme [cytosol]
N:heme [cytosol] (Severe acute respiratory syndrome coronavirus 2)
heme [cytosol]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
ROS and RNS production in phagocytes (Homo sapiens)
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
heme [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Selenoamino acid metabolism (Homo sapiens)
Metabolism of ingested SeMet, Sec, MeSec into H2Se (Homo sapiens)
SeHCys and Ser are dehydrated into SeCysta by CBS (Homo sapiens)
PXLP-K119-CBS tetramer [cytosol] (Homo sapiens)
heme [cytosol]
Sulfur amino acid metabolism (Homo sapiens)
Cysteine formation from homocysteine (Homo sapiens)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Homo sapiens)
PXLP-K119-CBS tetramer [cytosol] (Homo sapiens)
heme [cytosol]
Tryptophan catabolism (Homo sapiens)
IDO1 dioxygenates L-Trp to NFK (Homo sapiens)
IDO1 [cytosol] (Homo sapiens)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Homo sapiens)
IDO2 [cytosol] (Homo sapiens)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Homo sapiens)
TDO2 tetramer [cytosol] (Homo sapiens)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
NOSIP mediated eNOS trafficking (Homo sapiens)
eNOS binds NOSIP (Homo sapiens)
eNOS:NOSIP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Homo sapiens)
eNOS:NOSIP [Golgi membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
NOSTRIN mediated eNOS trafficking (Homo sapiens)
NOSTRIN mediated translocation of eNOS from plasma membrane (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Homo sapiens)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS activation (Homo sapiens)
AKT1 binds eNOS complex via HSP90 (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
AKT1 phosphorylates eNOS (Homo sapiens)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
CYGB binds O2 (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB dioxygenates NO (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Homo sapiens)
heme [cytosol]
depalmitoylation of eNOS (Homo sapiens)
myristoylated eNOS dimer [cytosol] (Homo sapiens)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS associates with Caveolin-1 (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Metabolism of porphyrins (Homo sapiens)
Heme biosynthesis (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Homo sapiens)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)
heme [cytosol]
Heme degradation (Homo sapiens)
HMOX1 dimer, HMOX2 cleave heme (Homo sapiens)
heme [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Homo sapiens)
BH2 binding can lead to eNOS uncoupling (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)
NOX2 complex:RAC1:GTP [plasma membrane] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
VEGFR2 mediated vascular permeability (Homo sapiens)
AKT1 binds eNOS complex via HSP90 (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
AKT1 phosphorylates eNOS (Homo sapiens)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Homo sapiens)
Signaling by Rho GTPases (Homo sapiens)
RHO GTPase Effectors (Homo sapiens)
RHO GTPases Activate NADPH Oxidases (Homo sapiens)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Homo sapiens)
NOX2 complex:RAC1:GTP [plasma membrane] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
RHO GTPase cycle (Homo sapiens)
RAC1 GTPase cycle (Homo sapiens)
RAC1 binds effectors at the plasma membrane (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Homo sapiens)
RAC1 effectors [cytosol] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
RAC3 GTPase cycle (Homo sapiens)
RAC3 binds effectors at the plasma membrane (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Homo sapiens)
RAC3 effectors [cytosol] (Homo sapiens)
NOX2 complex [plasma membrane] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
heme [cytosol]
Transport of small molecules (Homo sapiens)
ABC-family proteins mediated transport (Homo sapiens)
Mitochondrial ABC transporters (Homo sapiens)
ABC7, mABC1 and mABC2 mediate heme transport (Homo sapiens)
heme [cytosol]
Intracellular oxygen transport (Homo sapiens)
CYGB binds O2 (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB:O2 dissociates (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Homo sapiens)
CYGB dimer [cytosol] (Homo sapiens)
CYGB:heme [cytosol] (Homo sapiens)
heme [cytosol]
Myoglobin binds oxygen (Homo sapiens)
MB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Homo sapiens)
MB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Myoglobin:oxygen dissociates (Homo sapiens)
MB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Homo sapiens)
MB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Neuroglobin binds oxygen (Homo sapiens)
NGB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Homo sapiens)
NGB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Neuroglobin:oxygen dissociates (Homo sapiens)
NGB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Homo sapiens)
NGB:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Iron uptake and transport (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Homo sapiens)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Homo sapiens)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Homo sapiens)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Homo sapiens)
Erythrocytes take up carbon dioxide and release oxygen (Homo sapiens)
CYB5Rs reduce MetHb to HbA (Homo sapiens)
HbA [cytosol] (Homo sapiens)
Hemoglobin alpha:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Homo sapiens)
OxyHbA [cytosol] (Homo sapiens)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Homo sapiens)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Homo sapiens)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Homo sapiens)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Homo sapiens)
Hemoglobin A binds O2, releasing H+ and CO2 (Homo sapiens)
OxyHbA [cytosol] (Homo sapiens)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Homo sapiens)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Homo sapiens)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Homo sapiens)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Homo sapiens)
heme [cytosol]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Cytoprotection by HMOX1 (Mus musculus)
HMOX1 dimer, HMOX2 cleave heme (Mus musculus)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Mus musculus)
NOX2 generates superoxide from oxygen (Mus musculus)
NOX2 complex [phagocytic vesicle membrane] (Mus musculus)
Cytochrome b-245 [phagocytic vesicle membrane] (Mus musculus)
heme [cytosol]
Heme signaling (Mus musculus)
PGRMC2 binds Hemes (Mus musculus)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Mus musculus)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Mus musculus)
XPO1:BACH1:Hemes [cytosol] (Mus musculus)
BACH1:Hemes [cytosol] (Mus musculus)
Hemes [cytosol]
heme [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Sulfur amino acid metabolism (Mus musculus)
Cysteine formation from homocysteine (Mus musculus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Mus musculus)
PXLP-K119-CBS tetramer [cytosol] (Mus musculus)
heme [cytosol]
Tryptophan catabolism (Mus musculus)
IDO1 dioxygenates L-Trp to NFK (Mus musculus)
IDO1 [cytosol] (Mus musculus)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Mus musculus)
IDO2 [cytosol] (Mus musculus)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Mus musculus)
TDO2 tetramer [cytosol] (Mus musculus)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Mus musculus)
NOSIP mediated eNOS trafficking (Mus musculus)
eNOS binds NOSIP (Mus musculus)
eNOS:NOSIP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Mus musculus)
eNOS:NOSIP [Golgi membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
NOSTRIN mediated eNOS trafficking (Mus musculus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Mus musculus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Mus musculus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Mus musculus)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS activation (Mus musculus)
AKT1 binds eNOS complex via HSP90 (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
AKT1 phosphorylates eNOS (Mus musculus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
CYGB binds O2 (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB dioxygenates NO (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Mus musculus)
myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Mus musculus)
heme [cytosol]
depalmitoylation of eNOS (Mus musculus)
myristoylated eNOS dimer [cytosol] (Mus musculus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS associates with Caveolin-1 (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Metabolism of porphyrins (Mus musculus)
Heme biosynthesis (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Mus musculus)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Mus musculus)
heme [cytosol]
Heme degradation (Mus musculus)
HMOX1 dimer, HMOX2 cleave heme (Mus musculus)
heme [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Mus musculus)
BH2 binding can lead to eNOS uncoupling (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)
NOX2 complex:RAC1:GTP [plasma membrane] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
VEGFR2 mediated vascular permeability (Mus musculus)
AKT1 binds eNOS complex via HSP90 (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
AKT1 phosphorylates eNOS (Mus musculus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Mus musculus)
Signaling by Rho GTPases (Mus musculus)
RHO GTPase Effectors (Mus musculus)
RHO GTPases Activate NADPH Oxidases (Mus musculus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Mus musculus)
NOX2 complex:RAC1:GTP [plasma membrane] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
RHO GTPase cycle (Mus musculus)
RAC1 GTPase cycle (Mus musculus)
RAC1 binds effectors at the plasma membrane (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Mus musculus)
RAC1 effectors [cytosol] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
RAC3 GTPase cycle (Mus musculus)
RAC3 binds effectors at the plasma membrane (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Mus musculus)
RAC3 effectors [cytosol] (Mus musculus)
NOX2 complex [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Mus musculus)
heme [cytosol]
Transport of small molecules (Mus musculus)
ABC-family proteins mediated transport (Mus musculus)
Mitochondrial ABC transporters (Mus musculus)
ABC7, mABC1 and mABC2 mediate heme transport (Mus musculus)
heme [cytosol]
Intracellular oxygen transport (Mus musculus)
CYGB binds O2 (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB:O2 dissociates (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Mus musculus)
CYGB dimer [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Mus musculus)
heme [cytosol]
Myoglobin binds oxygen (Mus musculus)
MB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Mus musculus)
MB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Myoglobin:oxygen dissociates (Mus musculus)
MB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Mus musculus)
MB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Neuroglobin binds oxygen (Mus musculus)
NGB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Mus musculus)
NGB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Neuroglobin:oxygen dissociates (Mus musculus)
NGB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Mus musculus)
NGB:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Iron uptake and transport (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Mus musculus)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Mus musculus)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Mus musculus)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Mus musculus)
Erythrocytes take up carbon dioxide and release oxygen (Mus musculus)
CYB5Rs reduce MetHb to HbA (Mus musculus)
HbA [cytosol] (Mus musculus)
Hemoglobin alpha:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Mus musculus)
OxyHbA [cytosol] (Mus musculus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Mus musculus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Mus musculus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Mus musculus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Mus musculus)
Hemoglobin A binds O2, releasing H+ and CO2 (Mus musculus)
OxyHbA [cytosol] (Mus musculus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Mus musculus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Mus musculus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Mus musculus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Mus musculus)
heme [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nitric oxide: NOS3 activation and regulation (Plasmodium falciparum)
NOSIP mediated eNOS trafficking (Plasmodium falciparum)
eNOS binds NOSIP (Plasmodium falciparum)
eNOS:NOSIP [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Plasmodium falciparum)
eNOS:NOSIP [Golgi membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
eNOS activation (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
eNOS:CaM:HSP90 [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Plasmodium falciparum)
myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Plasmodium falciparum)
heme [cytosol]
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
Metabolism of porphyrins (Plasmodium falciparum)
Heme biosynthesis (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
heme [cytosol]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of cofactors (Plasmodium falciparum)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Plasmodium falciparum)
BH2 binding can lead to eNOS uncoupling (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
Signal Transduction (Plasmodium falciparum)
Signaling by Nuclear Receptors (Plasmodium falciparum)
ESR-mediated signaling (Plasmodium falciparum)
Extra-nuclear estrogen signaling (Plasmodium falciparum)
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by VEGF (Plasmodium falciparum)
VEGFA-VEGFR2 Pathway (Plasmodium falciparum)
VEGFR2 mediated vascular permeability (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
eNOS:CaM:HSP90 [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
heme [cytosol]
Transport of small molecules (Plasmodium falciparum)
Iron uptake and transport (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
heme [cytosol]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Cytoprotection by HMOX1 (Rattus norvegicus)
HMOX1 dimer, HMOX2 cleave heme (Rattus norvegicus)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Rattus norvegicus)
NOX2 generates superoxide from oxygen (Rattus norvegicus)
NOX2 complex [phagocytic vesicle membrane] (Rattus norvegicus)
Cytochrome b-245 [phagocytic vesicle membrane] (Rattus norvegicus)
heme [cytosol]
Heme signaling (Rattus norvegicus)
PGRMC2 binds Hemes (Rattus norvegicus)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Rattus norvegicus)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Rattus norvegicus)
XPO1:BACH1:Hemes [cytosol] (Rattus norvegicus)
BACH1:Hemes [cytosol] (Rattus norvegicus)
Hemes [cytosol]
heme [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Sulfur amino acid metabolism (Rattus norvegicus)
Cysteine formation from homocysteine (Rattus norvegicus)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Rattus norvegicus)
PXLP-K119-CBS tetramer [cytosol] (Rattus norvegicus)
heme [cytosol]
Tryptophan catabolism (Rattus norvegicus)
IDO1 dioxygenates L-Trp to NFK (Rattus norvegicus)
IDO1 [cytosol] (Rattus norvegicus)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Rattus norvegicus)
IDO2 [cytosol] (Rattus norvegicus)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Rattus norvegicus)
TDO2 tetramer [cytosol] (Rattus norvegicus)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Rattus norvegicus)
NOSIP mediated eNOS trafficking (Rattus norvegicus)
eNOS binds NOSIP (Rattus norvegicus)
eNOS:NOSIP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Rattus norvegicus)
eNOS:NOSIP [Golgi membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
NOSTRIN mediated eNOS trafficking (Rattus norvegicus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Rattus norvegicus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Rattus norvegicus)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS activation (Rattus norvegicus)
AKT1 binds eNOS complex via HSP90 (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
AKT1 phosphorylates eNOS (Rattus norvegicus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
CYGB binds O2 (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB dioxygenates NO (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Rattus norvegicus)
myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
heme [cytosol]
depalmitoylation of eNOS (Rattus norvegicus)
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS associates with Caveolin-1 (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Metabolism of porphyrins (Rattus norvegicus)
Heme biosynthesis (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
heme [cytosol]
Heme degradation (Rattus norvegicus)
HMOX1 dimer, HMOX2 cleave heme (Rattus norvegicus)
heme [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Rattus norvegicus)
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)
NOX2 complex:RAC1:GTP [plasma membrane] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
VEGFR2 mediated vascular permeability (Rattus norvegicus)
AKT1 binds eNOS complex via HSP90 (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
AKT1 phosphorylates eNOS (Rattus norvegicus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Rattus norvegicus)
Signaling by Rho GTPases (Rattus norvegicus)
RHO GTPase Effectors (Rattus norvegicus)
RHO GTPases Activate NADPH Oxidases (Rattus norvegicus)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Rattus norvegicus)
NOX2 complex:RAC1:GTP [plasma membrane] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
RHO GTPase cycle (Rattus norvegicus)
RAC1 GTPase cycle (Rattus norvegicus)
RAC1 binds effectors at the plasma membrane (Rattus norvegicus)
RAC1 effectors [cytosol] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Rattus norvegicus)
RAC1 effectors [cytosol] (Rattus norvegicus)
NOX2 complex [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
heme [cytosol]
Transport of small molecules (Rattus norvegicus)
ABC-family proteins mediated transport (Rattus norvegicus)
Mitochondrial ABC transporters (Rattus norvegicus)
ABC7, mABC1 and mABC2 mediate heme transport (Rattus norvegicus)
heme [cytosol]
Intracellular oxygen transport (Rattus norvegicus)
CYGB binds O2 (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB:O2 dissociates (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Rattus norvegicus)
CYGB dimer [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Rattus norvegicus)
heme [cytosol]
Myoglobin binds oxygen (Rattus norvegicus)
MB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Rattus norvegicus)
MB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Myoglobin:oxygen dissociates (Rattus norvegicus)
MB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Rattus norvegicus)
MB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Neuroglobin binds oxygen (Rattus norvegicus)
NGB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Rattus norvegicus)
NGB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Neuroglobin:oxygen dissociates (Rattus norvegicus)
NGB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Rattus norvegicus)
NGB:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Iron uptake and transport (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Rattus norvegicus)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Rattus norvegicus)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Rattus norvegicus)
Erythrocytes take up carbon dioxide and release oxygen (Rattus norvegicus)
CYB5Rs reduce MetHb to HbA (Rattus norvegicus)
HbA [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Rattus norvegicus)
OxyHbA [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Rattus norvegicus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Rattus norvegicus)
Hemoglobin A binds O2, releasing H+ and CO2 (Rattus norvegicus)
OxyHbA [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Rattus norvegicus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Rattus norvegicus)
heme [cytosol]
Cellular responses to stimuli (Saccharomyces cerevisiae)
Cellular responses to stress (Saccharomyces cerevisiae)
Heme signaling (Saccharomyces cerevisiae)
PGRMC2 binds Hemes (Saccharomyces cerevisiae)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Saccharomyces cerevisiae)
Hemes [cytosol]
heme [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Sulfur amino acid metabolism (Saccharomyces cerevisiae)
Cysteine formation from homocysteine (Saccharomyces cerevisiae)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Saccharomyces cerevisiae)
PXLP-K119-CBS tetramer [cytosol] (Saccharomyces cerevisiae)
heme [cytosol]
Tryptophan catabolism (Saccharomyces cerevisiae)
IDO1 dioxygenates L-Trp to NFK (Saccharomyces cerevisiae)
IDO1 [cytosol] (Saccharomyces cerevisiae)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Saccharomyces cerevisiae)
IDO2 [cytosol] (Saccharomyces cerevisiae)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Saccharomyces cerevisiae)
myristoylated eNOS dimer [Golgi membrane] (Saccharomyces cerevisiae)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
heme [cytosol]
depalmitoylation of eNOS (Saccharomyces cerevisiae)
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
Metabolism of porphyrins (Saccharomyces cerevisiae)
Heme biosynthesis (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
heme [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
heme [cytosol]
Transport of small molecules (Saccharomyces cerevisiae)
ABC-family proteins mediated transport (Saccharomyces cerevisiae)
Mitochondrial ABC transporters (Saccharomyces cerevisiae)
ABC7, mABC1 and mABC2 mediate heme transport (Saccharomyces cerevisiae)
heme [cytosol]
Iron uptake and transport (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Saccharomyces cerevisiae)
Hemes [cytosol]
heme [cytosol]
Cellular responses to stimuli (Schizosaccharomyces pombe)
Cellular responses to stress (Schizosaccharomyces pombe)
Heme signaling (Schizosaccharomyces pombe)
PGRMC2 binds Hemes (Schizosaccharomyces pombe)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Schizosaccharomyces pombe)
Hemes [cytosol]
heme [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nitric oxide: NOS3 activation and regulation (Schizosaccharomyces pombe)
eNOS activation (Schizosaccharomyces pombe)
AKT1 binds eNOS complex via HSP90 (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Schizosaccharomyces pombe)
myristoylated eNOS dimer [Golgi membrane] (Schizosaccharomyces pombe)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
heme [cytosol]
depalmitoylation of eNOS (Schizosaccharomyces pombe)
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of cofactors (Schizosaccharomyces pombe)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Schizosaccharomyces pombe)
BH2 binding can lead to eNOS uncoupling (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Extra-nuclear estrogen signaling (Schizosaccharomyces pombe)
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
Signaling by VEGF (Schizosaccharomyces pombe)
VEGFA-VEGFR2 Pathway (Schizosaccharomyces pombe)
VEGFR2 mediated vascular permeability (Schizosaccharomyces pombe)
AKT1 binds eNOS complex via HSP90 (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
heme [cytosol]
Transport of small molecules (Schizosaccharomyces pombe)
ABC-family proteins mediated transport (Schizosaccharomyces pombe)
Mitochondrial ABC transporters (Schizosaccharomyces pombe)
ABC7, mABC1 and mABC2 mediate heme transport (Schizosaccharomyces pombe)
heme [cytosol]
Iron uptake and transport (Schizosaccharomyces pombe)
SLC46A1 transports hemes from extracellular region to cytosol (Schizosaccharomyces pombe)
Hemes [cytosol]
heme [cytosol]
Cellular responses to stimuli (Sus scrofa)
Cellular responses to stress (Sus scrofa)
Cellular response to chemical stress (Sus scrofa)
Cytoprotection by HMOX1 (Sus scrofa)
HMOX1 dimer, HMOX2 cleave heme (Sus scrofa)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Sus scrofa)
NOX2 generates superoxide from oxygen (Sus scrofa)
NOX2 complex [phagocytic vesicle membrane] (Sus scrofa)
Cytochrome b-245 [phagocytic vesicle membrane] (Sus scrofa)
heme [cytosol]
Heme signaling (Sus scrofa)
PGRMC2 binds Hemes (Sus scrofa)
Hemes [cytosol]
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)
Hemes [cytosol]
heme [cytosol]
XPO1:BACH1:Hemes are transported out of the nucleus (Sus scrofa)
XPO1:BACH1:Hemes [cytosol] (Sus scrofa)
BACH1:Hemes [cytosol] (Sus scrofa)
Hemes [cytosol]
heme [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Sulfur amino acid metabolism (Sus scrofa)
Cysteine formation from homocysteine (Sus scrofa)
PXLP-CBS tetramers condenses HCYS and L-Ser to form L-Cystathionine (Sus scrofa)
PXLP-K119-CBS tetramer [cytosol] (Sus scrofa)
heme [cytosol]
Tryptophan catabolism (Sus scrofa)
IDO1 dioxygenates L-Trp to NFK (Sus scrofa)
IDO1 [cytosol] (Sus scrofa)
heme [cytosol]
IDO2 dioxygenates L-Trp to NFK (Sus scrofa)
IDO2 [cytosol] (Sus scrofa)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Sus scrofa)
TDO2 tetramer [cytosol] (Sus scrofa)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Sus scrofa)
NOSIP mediated eNOS trafficking (Sus scrofa)
eNOS binds NOSIP (Sus scrofa)
eNOS:NOSIP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Sus scrofa)
eNOS:NOSIP [Golgi membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
heme [cytosol]
eNOS:NOSIP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
NOSTRIN mediated eNOS trafficking (Sus scrofa)
NOSTRIN mediated translocation of eNOS from plasma membrane (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Sus scrofa)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS activation (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
BH2 binding can lead to eNOS uncoupling (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
CYGB binds O2 (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB dioxygenates NO (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Uncoupled eNOS favours the formation of superoxide (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Sus scrofa)
myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
heme [cytosol]
myristoylated eNOS dimer [cytosol] (Sus scrofa)
heme [cytosol]
depalmitoylation of eNOS (Sus scrofa)
myristoylated eNOS dimer [cytosol] (Sus scrofa)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS associates with Caveolin-1 (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS translocation from Golgi to Caveolae (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Metabolism of porphyrins (Sus scrofa)
Heme biosynthesis (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Sus scrofa)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Sus scrofa)
heme [cytosol]
Heme degradation (Sus scrofa)
HMOX1 dimer, HMOX2 cleave heme (Sus scrofa)
heme [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Sus scrofa)
BH2 binding can lead to eNOS uncoupling (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)
NOX2 complex:RAC1:GTP [plasma membrane] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
VEGFR2 mediated vascular permeability (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Sus scrofa)
Signaling by Rho GTPases (Sus scrofa)
RHO GTPase Effectors (Sus scrofa)
RHO GTPases Activate NADPH Oxidases (Sus scrofa)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Sus scrofa)
NOX2 complex:RAC1:GTP [plasma membrane] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
RHO GTPase cycle (Sus scrofa)
RAC1 GTPase cycle (Sus scrofa)
RAC1 binds effectors at the plasma membrane (Sus scrofa)
RAC1 effectors [cytosol] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Sus scrofa)
RAC1 effectors [cytosol] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
RAC3 GTPase cycle (Sus scrofa)
RAC3 binds effectors at the plasma membrane (Sus scrofa)
RAC3 effectors [cytosol] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Sus scrofa)
RAC3 effectors [cytosol] (Sus scrofa)
NOX2 complex [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
heme [cytosol]
Transport of small molecules (Sus scrofa)
ABC-family proteins mediated transport (Sus scrofa)
Mitochondrial ABC transporters (Sus scrofa)
ABC7, mABC1 and mABC2 mediate heme transport (Sus scrofa)
heme [cytosol]
Intracellular oxygen transport (Sus scrofa)
CYGB binds O2 (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB:O2 dissociates (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Sus scrofa)
CYGB dimer [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Sus scrofa)
heme [cytosol]
Myoglobin binds oxygen (Sus scrofa)
MB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Sus scrofa)
MB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Myoglobin:oxygen dissociates (Sus scrofa)
MB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
MB:ferroheme b:O2 [cytosol] (Sus scrofa)
MB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Neuroglobin binds oxygen (Sus scrofa)
NGB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Sus scrofa)
NGB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Neuroglobin:oxygen dissociates (Sus scrofa)
NGB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Sus scrofa)
NGB:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Iron uptake and transport (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Sus scrofa)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Sus scrofa)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Sus scrofa)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Sus scrofa)
Erythrocytes take up carbon dioxide and release oxygen (Sus scrofa)
CYB5Rs reduce MetHb to HbA (Sus scrofa)
HbA [cytosol] (Sus scrofa)
Hemoglobin alpha:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Sus scrofa)
OxyHbA [cytosol] (Sus scrofa)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Sus scrofa)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Sus scrofa)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Sus scrofa)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Sus scrofa)
Hemoglobin A binds O2, releasing H+ and CO2 (Sus scrofa)
OxyHbA [cytosol] (Sus scrofa)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Sus scrofa)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Sus scrofa)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Sus scrofa)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Sus scrofa)
heme [cytosol]
Cellular responses to stimuli (Xenopus tropicalis)
Cellular responses to stress (Xenopus tropicalis)
Cellular response to chemical stress (Xenopus tropicalis)
Cytoprotection by HMOX1 (Xenopus tropicalis)
HMOX1 dimer, HMOX2 cleave heme (Xenopus tropicalis)
heme [cytosol]
Detoxification of Reactive Oxygen Species (Xenopus tropicalis)
NOX2 generates superoxide from oxygen (Xenopus tropicalis)
NOX2 complex [phagocytic vesicle membrane] (Xenopus tropicalis)
Cytochrome b-245 [phagocytic vesicle membrane] (Xenopus tropicalis)
heme [cytosol]
Heme signaling (Xenopus tropicalis)
SLC46A1 transports hemes from extracellular region to cytosol (Xenopus tropicalis)
Hemes [cytosol]
heme [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Tryptophan catabolism (Xenopus tropicalis)
IDO2 dioxygenates L-Trp to NFK (Xenopus tropicalis)
IDO2 [cytosol] (Xenopus tropicalis)
heme [cytosol]
TDO tetramer dioxygenates L-Trp to NFK (Xenopus tropicalis)
TDO2 tetramer [cytosol] (Xenopus tropicalis)
heme [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Xenopus tropicalis)
eNOS activation (Xenopus tropicalis)
CYGB binds O2 (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB dioxygenates NO (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
Metabolism of porphyrins (Xenopus tropicalis)
Heme biosynthesis (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Xenopus tropicalis)
heme [cytosol]
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Xenopus tropicalis)
heme [cytosol]
Heme degradation (Xenopus tropicalis)
HMOX1 dimer, HMOX2 cleave heme (Xenopus tropicalis)
heme [cytosol]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by VEGF (Xenopus tropicalis)
VEGFA-VEGFR2 Pathway (Xenopus tropicalis)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)
NOX2 complex:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Xenopus tropicalis)
Signaling by Rho GTPases (Xenopus tropicalis)
RHO GTPase Effectors (Xenopus tropicalis)
RHO GTPases Activate NADPH Oxidases (Xenopus tropicalis)
NADPH oxidase 2 (NOX2) complex binds RAC1 (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
NOX2 complex:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
NADPH oxidase 2 generates superoxide from oxygen (Xenopus tropicalis)
NOX2 complex:RAC1:GTP [plasma membrane] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
RHO GTPase cycle (Xenopus tropicalis)
RAC1 GTPase cycle (Xenopus tropicalis)
RAC1 binds effectors at the plasma membrane (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
RAC1:GTP:RAC1 effectors [plasma membrane] (Xenopus tropicalis)
RAC1 effectors [cytosol] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
RAC3 GTPase cycle (Xenopus tropicalis)
RAC3 binds effectors at the plasma membrane (Xenopus tropicalis)
RAC3 effectors [cytosol] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
RAC3:GTP:RAC3 effectors [plasma membrane] (Xenopus tropicalis)
RAC3 effectors [cytosol] (Xenopus tropicalis)
NOX2 complex [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
heme [cytosol]
Transport of small molecules (Xenopus tropicalis)
ABC-family proteins mediated transport (Xenopus tropicalis)
Mitochondrial ABC transporters (Xenopus tropicalis)
ABC7, mABC1 and mABC2 mediate heme transport (Xenopus tropicalis)
heme [cytosol]
Intracellular oxygen transport (Xenopus tropicalis)
CYGB binds O2 (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB:O2 dissociates (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
CYGB dimer:O2 [cytosol] (Xenopus tropicalis)
CYGB dimer [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Xenopus tropicalis)
heme [cytosol]
Neuroglobin binds oxygen (Xenopus tropicalis)
NGB:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Xenopus tropicalis)
NGB:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Neuroglobin:oxygen dissociates (Xenopus tropicalis)
NGB:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
NGB:ferroheme b:O2 [cytosol] (Xenopus tropicalis)
NGB:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Iron uptake and transport (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
heme [cytosol]
FLVCR1-1 transports heme from cytosol to extracellular region (Xenopus tropicalis)
heme [cytosol]
HMOX1 dimer, HMOX2 cleave heme (Xenopus tropicalis)
heme [cytosol]
SLC46A1 transports hemes from extracellular region to cytosol (Xenopus tropicalis)
Hemes [cytosol]
heme [cytosol]
O2/CO2 exchange in erythrocytes (Xenopus tropicalis)
Erythrocytes take up carbon dioxide and release oxygen (Xenopus tropicalis)
CYB5Rs reduce MetHb to HbA (Xenopus tropicalis)
HbA [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Hemoglobin beta:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Hemoglobin A is protonated and carbamated causing release of oxygen (Xenopus tropicalis)
OxyHbA [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Xenopus tropicalis)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Erythrocytes take up oxygen and release carbon dioxide (Xenopus tropicalis)
Hemoglobin A binds O2, releasing H+ and CO2 (Xenopus tropicalis)
OxyHbA [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
heme [cytosol]
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
heme [cytosol]
Protonated Carbamino DeoxyHbA [cytosol] (Xenopus tropicalis)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Xenopus tropicalis)
heme [cytosol]
External Reference Information
External Reference
ferroheme b(2-) [ChEBI:60344]
Participates
as a component of
MB:ferroheme b [cytosol] (Canis familiaris)
MB:ferroheme b [cytosol] (Danio rerio)
MB:ferroheme b [cytosol] (Gallus gallus)
MB:ferroheme b [cytosol] (Bos taurus)
MB:ferroheme b [cytosol] (Sus scrofa)
MB:ferroheme b [cytosol] (Rattus norvegicus)
MB:ferroheme b [cytosol] (Mus musculus)
MB:ferroheme b [cytosol] (Homo sapiens)
NGB:ferroheme b [cytosol] (Xenopus tropicalis)
NGB:ferroheme b [cytosol] (Danio rerio)
NGB:ferroheme b [cytosol] (Rattus norvegicus)
NGB:ferroheme b [cytosol] (Gallus gallus)
NGB:ferroheme b [cytosol] (Sus scrofa)
NGB:ferroheme b [cytosol] (Canis familiaris)
NGB:ferroheme b [cytosol] (Mus musculus)
NGB:ferroheme b [cytosol] (Bos taurus)
NGB:ferroheme b [cytosol] (Caenorhabditis elegans)
NGB:ferroheme b [cytosol] (Homo sapiens)
Hemoglobin alpha:ferroheme b [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferroheme b [cytosol] (Mus musculus)
Hemoglobin alpha:ferroheme b [cytosol] (Danio rerio)
Hemoglobin alpha:ferroheme b [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferroheme b [cytosol] (Canis familiaris)
Hemoglobin alpha:ferroheme b [cytosol] (Sus scrofa)
Hemoglobin alpha:ferroheme b [cytosol] (Bos taurus)
Hemoglobin alpha:ferroheme b [cytosol] (Gallus gallus)
Hemoglobin alpha:ferroheme b [cytosol] (Homo sapiens)
Hemoglobin beta:ferroheme b [cytosol] (Rattus norvegicus)
Hemoglobin beta:ferroheme b [cytosol] (Bos taurus)
Hemoglobin beta:ferroheme b [cytosol] (Xenopus tropicalis)
Hemoglobin beta:ferroheme b [cytosol] (Mus musculus)
Hemoglobin beta:ferroheme b [cytosol] (Canis familiaris)
Hemoglobin beta:ferroheme b [cytosol] (Danio rerio)
Hemoglobin beta:ferroheme b [cytosol] (Gallus gallus)
Hemoglobin beta:ferroheme b [cytosol] (Sus scrofa)
Hemoglobin beta:ferroheme b [cytosol] (Homo sapiens)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Canis familiaris)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Xenopus tropicalis)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Sus scrofa)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Rattus norvegicus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Bos taurus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Gallus gallus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Mus musculus)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Danio rerio)
Protonated Carbamino Hemoglobin alpha:ferroheme b [cytosol] (Homo sapiens)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Bos taurus)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Mus musculus)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Danio rerio)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Gallus gallus)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Xenopus tropicalis)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Sus scrofa)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Canis familiaris)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Rattus norvegicus)
Protonated Carbamino Hemoglobin beta: ferroheme b [cytosol] (Homo sapiens)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Bos taurus)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Gallus gallus)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Mus musculus)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Danio rerio)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Canis familiaris)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Sus scrofa)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
Hemoglobin beta:ferroheme b:oxygen [cytosol] (Homo sapiens)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Mus musculus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Rattus norvegicus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Canis familiaris)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Sus scrofa)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Gallus gallus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Xenopus tropicalis)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Danio rerio)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Bos taurus)
Hemoglobin alpha:ferroheme b:oxygen [cytosol] (Homo sapiens)
Cytochrome b-245 [plasma membrane] (Bos taurus)
Cytochrome b-245 [plasma membrane] (Sus scrofa)
Cytochrome b-245 [plasma membrane] (Mus musculus)
Cytochrome b-245 [plasma membrane] (Xenopus tropicalis)
Cytochrome b-245 [plasma membrane] (Danio rerio)
Cytochrome b-245 [plasma membrane] (Gallus gallus)
Cytochrome b-245 [plasma membrane] (Canis familiaris)
Cytochrome b-245 [plasma membrane] (Rattus norvegicus)
Cytochrome b-245 [plasma membrane] (Homo sapiens)
GlbN:Heme dimer [cytosol] (Mycobacterium tuberculosis)
BfrA dimer [cytosol] (Mycobacterium tuberculosis)
KatG dimer [cytosol] (Mycobacterium tuberculosis)
Cbs tetramer [cytosol] (Rattus norvegicus)
IDO2 [cytosol] (Canis familiaris)
IDO2 [cytosol] (Rattus norvegicus)
IDO2 [cytosol] (Saccharomyces cerevisiae)
IDO2 [cytosol] (Xenopus tropicalis)
IDO2 [cytosol] (Mus musculus)
IDO2 [cytosol] (Danio rerio)
IDO2 [cytosol] (Gallus gallus)
IDO2 [cytosol] (Sus scrofa)
IDO2 [cytosol] (Bos taurus)
IDO2 [cytosol] (Homo sapiens)
TDO2 tetramer [cytosol] (Gallus gallus)
TDO2 tetramer [cytosol] (Dictyostelium discoideum)
TDO2 tetramer [cytosol] (Rattus norvegicus)
TDO2 tetramer [cytosol] (Mus musculus)
TDO2 tetramer [cytosol] (Caenorhabditis elegans)
TDO2 tetramer [cytosol] (Xenopus tropicalis)
TDO2 tetramer [cytosol] (Drosophila melanogaster)
TDO2 tetramer [cytosol] (Canis familiaris)
TDO2 tetramer [cytosol] (Sus scrofa)
TDO2 tetramer [cytosol] (Bos taurus)
TDO2 tetramer [cytosol] (Danio rerio)
TDO2 tetramer [cytosol] (Homo sapiens)
IDO1 [cytosol] (Sus scrofa)
IDO1 [cytosol] (Mus musculus)
IDO1 [cytosol] (Bos taurus)
IDO1 [cytosol] (Canis familiaris)
IDO1 [cytosol] (Rattus norvegicus)
IDO1 [cytosol] (Saccharomyces cerevisiae)
IDO1 [cytosol] (Homo sapiens)
Cytochrome b-245 [phagocytic vesicle membrane] (Sus scrofa)
Cytochrome b-245 [phagocytic vesicle membrane] (Xenopus tropicalis)
Cytochrome b-245 [phagocytic vesicle membrane] (Gallus gallus)
Cytochrome b-245 [phagocytic vesicle membrane] (Bos taurus)
Cytochrome b-245 [phagocytic vesicle membrane] (Canis familiaris)
Cytochrome b-245 [phagocytic vesicle membrane] (Mus musculus)
Cytochrome b-245 [phagocytic vesicle membrane] (Rattus norvegicus)
Cytochrome b-245 [phagocytic vesicle membrane] (Danio rerio)
Cytochrome b-245 [phagocytic vesicle membrane] (Homo sapiens)
PXLP-K119-CBS tetramer [cytosol] (Bos taurus)
PXLP-K119-CBS tetramer [cytosol] (Drosophila melanogaster)
PXLP-K119-CBS tetramer [cytosol] (Sus scrofa)
PXLP-K119-CBS tetramer [cytosol] (Caenorhabditis elegans)
PXLP-K119-CBS tetramer [cytosol] (Dictyostelium discoideum)
PXLP-K119-CBS tetramer [cytosol] (Mus musculus)
PXLP-K119-CBS tetramer [cytosol] (Gallus gallus)
PXLP-K119-CBS tetramer [cytosol] (Danio rerio)
PXLP-K119-CBS tetramer [cytosol] (Canis familiaris)
PXLP-K119-CBS tetramer [cytosol] (Saccharomyces cerevisiae)
PXLP-K119-CBS tetramer [cytosol] (Rattus norvegicus)
PXLP-K119-CBS tetramer [cytosol] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Homo sapiens)
CYGB:heme [cytosol] (Canis familiaris)
CYGB:heme [cytosol] (Rattus norvegicus)
CYGB:heme [cytosol] (Danio rerio)
CYGB:heme [cytosol] (Bos taurus)
CYGB:heme [cytosol] (Xenopus tropicalis)
CYGB:heme [cytosol] (Sus scrofa)
CYGB:heme [cytosol] (Mus musculus)
CYGB:heme [cytosol] (Gallus gallus)
CYGB:heme [cytosol] (Caenorhabditis elegans)
CYGB:heme [cytosol] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
N:heme [cytosol] (Severe acute respiratory syndrome coronavirus 2)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
myristoylated eNOS dimer [cytosol] (Homo sapiens)
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
myristoylated eNOS dimer [cytosol] (Mus musculus)
myristoylated eNOS dimer [cytosol] (Plasmodium falciparum)
myristoylated eNOS dimer [cytosol] (Bos taurus)
myristoylated eNOS dimer [cytosol] (Sus scrofa)
myristoylated eNOS dimer [cytosol] (Gallus gallus)
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Saccharomyces cerevisiae)
myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
myristoylated eNOS dimer [Golgi membrane] (Gallus gallus)
myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
myristoylated eNOS dimer [Golgi membrane] (Schizosaccharomyces pombe)
as an input of
ABCG2 tetramer transports heme from cytosol to extracellular region (Plasmodium falciparum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Saccharomyces cerevisiae)
ABCG2 tetramer transports heme from cytosol to extracellular region (Dictyostelium discoideum)
ABCG2 tetramer transports heme from cytosol to extracellular region (Caenorhabditis elegans)
ABCG2 tetramer transports heme from cytosol to extracellular region (Xenopus tropicalis)
ABCG2 tetramer transports heme from cytosol to extracellular region (Sus scrofa)
ABCG2 tetramer transports heme from cytosol to extracellular region (Bos taurus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Canis familiaris)
ABCG2 tetramer transports heme from cytosol to extracellular region (Rattus norvegicus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Mus musculus)
ABCG2 tetramer transports heme from cytosol to extracellular region (Homo sapiens)
ABCG2 tetramer transports heme from cytosol to extracellular region (Drosophila melanogaster)
HMOX1 dimer, HMOX2 cleave heme (Gallus gallus)
HMOX1 dimer, HMOX2 cleave heme (Xenopus tropicalis)
HMOX1 dimer, HMOX2 cleave heme (Danio rerio)
HMOX1 dimer, HMOX2 cleave heme (Sus scrofa)
HMOX1 dimer, HMOX2 cleave heme (Bos taurus)
HMOX1 dimer, HMOX2 cleave heme (Canis familiaris)
HMOX1 dimer, HMOX2 cleave heme (Rattus norvegicus)
HMOX1 dimer, HMOX2 cleave heme (Mus musculus)
HMOX1 dimer, HMOX2 cleave heme (Homo sapiens)
HMOX1 dimer, HMOX2 cleave heme (Drosophila melanogaster)
FLVCR1-1 transports heme from cytosol to extracellular region (Caenorhabditis elegans)
FLVCR1-1 transports heme from cytosol to extracellular region (Gallus gallus)
FLVCR1-1 transports heme from cytosol to extracellular region (Xenopus tropicalis)
FLVCR1-1 transports heme from cytosol to extracellular region (Sus scrofa)
FLVCR1-1 transports heme from cytosol to extracellular region (Bos taurus)
FLVCR1-1 transports heme from cytosol to extracellular region (Canis familiaris)
FLVCR1-1 transports heme from cytosol to extracellular region (Mus musculus)
FLVCR1-1 transports heme from cytosol to extracellular region (Homo sapiens)
FLVCR1-1 transports heme from cytosol to extracellular region (Drosophila melanogaster)
N binds to heme (Homo sapiens)
as an output of
ABC7, mABC1 and mABC2 mediate heme transport (Saccharomyces cerevisiae)
ABC7, mABC1 and mABC2 mediate heme transport (Schizosaccharomyces pombe)
ABC7, mABC1 and mABC2 mediate heme transport (Dictyostelium discoideum)
ABC7, mABC1 and mABC2 mediate heme transport (Caenorhabditis elegans)
ABC7, mABC1 and mABC2 mediate heme transport (Drosophila melanogaster)
ABC7, mABC1 and mABC2 mediate heme transport (Gallus gallus)
ABC7, mABC1 and mABC2 mediate heme transport (Xenopus tropicalis)
ABC7, mABC1 and mABC2 mediate heme transport (Danio rerio)
ABC7, mABC1 and mABC2 mediate heme transport (Sus scrofa)
ABC7, mABC1 and mABC2 mediate heme transport (Bos taurus)
ABC7, mABC1 and mABC2 mediate heme transport (Canis familiaris)
ABC7, mABC1 and mABC2 mediate heme transport (Rattus norvegicus)
ABC7, mABC1 and mABC2 mediate heme transport (Mus musculus)
ABC7, mABC1 and mABC2 mediate heme transport (Homo sapiens)
Nitric oxide oxidizes to nitrosyl ion (Homo sapiens)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Homo sapiens)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Mus musculus)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Canis familiaris)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Bos taurus)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Sus scrofa)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Xenopus tropicalis)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Gallus gallus)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Drosophila melanogaster)
FLVCR1-2 transports heme from mitochondrial matrix to cytosol (Caenorhabditis elegans)
as a candidate of
Hemes [cytosol]
Other forms of this molecule
heme [mitochondrial outer membrane]
ferroheme b [endocytic vesicle lumen]
heme [nucleoplasm]
heme [nuclear envelope]
heme [peroxisomal matrix]
heme [plasma membrane]
heme [extracellular region]
heme [mitochondrial matrix]
Cross References
COMPOUND
C00032
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