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What is Reactome ?
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FMN [cytosol]
Stable Identifier
R-ALL-73524
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
Flavin mononucleotide, Riboflavin-5-phosphate
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase II - Conjugation of compounds (Bos taurus)
Methylation (Bos taurus)
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
MTRR:MTR:MeCbl [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Metabolism of amine-derived hormones (Bos taurus)
Thyroxine biosynthesis (Bos taurus)
Diiodinated tyrosine can be deiodinated (Bos taurus)
DEHAL1:FMN [plasma membrane] (Bos taurus)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Bos taurus)
DEHAL1:FMN [plasma membrane] (Bos taurus)
FMN [cytosol]
Sulfur amino acid metabolism (Bos taurus)
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
MTRR:MTR:MeCbl [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Bos taurus)
NOSIP mediated eNOS trafficking (Bos taurus)
eNOS binds NOSIP (Bos taurus)
eNOS:NOSIP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Bos taurus)
eNOS:NOSIP [Golgi membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
NOSTRIN mediated eNOS trafficking (Bos taurus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Bos taurus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Bos taurus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Bos taurus)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS activation (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Bos taurus)
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Bos taurus)
myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Bos taurus)
FMN [cytosol]
depalmitoylation of eNOS (Bos taurus)
myristoylated eNOS dimer [cytosol] (Bos taurus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS associates with Caveolin-1 (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Metabolism of nucleotides (Bos taurus)
Nucleotide catabolism (Bos taurus)
Pyrimidine catabolism (Bos taurus)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Bos taurus)
DPYD dimer [cytosol] (Bos taurus)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Bos taurus)
DPYD dimer [cytosol] (Bos taurus)
FMN [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of cofactors (Bos taurus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Bos taurus)
BH2 binding can lead to eNOS uncoupling (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Bos taurus)
Cobalamin (Cbl) metabolism (Bos taurus)
MTR transfers CH3 from MeCbl to HCYS (Bos taurus)
MTRR:MTR:MeCbl [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Bos taurus)
MTRR:MTR:MeCbl [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Bos taurus)
MTRR:MTR [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Bos taurus)
MTRR:MTR [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Bos taurus)
MTRR:MTR [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Bos taurus)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Bos taurus)
2xENPP1 hydrolyzes FAD to FMN (Bos taurus)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Bos taurus)
FMN [cytosol]
FLAD1 phosphorylates FMN (Bos taurus)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Bos taurus)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Bos taurus)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Bos taurus)
Coenzyme A biosynthesis (Bos taurus)
3xPPCDC:3FMN decarboxylates PPC (Bos taurus)
3xPPCDC:3xFMN [cytosol] (Bos taurus)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Bos taurus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Bos taurus)
2xPNPO:2xFMN [cytosol] (Bos taurus)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Bos taurus)
2xPNPO:2xFMN [cytosol] (Bos taurus)
FMN [cytosol]
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated vascular permeability (Bos taurus)
AKT1 phosphorylates eNOS (Bos taurus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Bos taurus)
eNOS:CaM:HSP90 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Bos taurus)
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS synthesizes NO (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Bos taurus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Bos taurus)
eNOS:Caveolin-1 [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
FMN [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Methylation (Caenorhabditis elegans)
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
MTRR:MTR:MeCbl [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of amine-derived hormones (Caenorhabditis elegans)
Thyroxine biosynthesis (Caenorhabditis elegans)
Diiodinated tyrosine can be deiodinated (Caenorhabditis elegans)
DEHAL1:FMN [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Caenorhabditis elegans)
DEHAL1:FMN [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Sulfur amino acid metabolism (Caenorhabditis elegans)
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
MTRR:MTR:MeCbl [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Caenorhabditis elegans)
eNOS activation (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
eNOS:CaM:HSP90 [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide catabolism (Caenorhabditis elegans)
Pyrimidine catabolism (Caenorhabditis elegans)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Caenorhabditis elegans)
DPYD dimer [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Caenorhabditis elegans)
DPYD dimer [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of cofactors (Caenorhabditis elegans)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Caenorhabditis elegans)
BH2 binding can lead to eNOS uncoupling (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Caenorhabditis elegans)
Cobalamin (Cbl) metabolism (Caenorhabditis elegans)
MTR transfers CH3 from MeCbl to HCYS (Caenorhabditis elegans)
MTRR:MTR:MeCbl [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Caenorhabditis elegans)
MTRR:MTR:MeCbl [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Caenorhabditis elegans)
MTRR:MTR [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Caenorhabditis elegans)
MTRR:MTR [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Caenorhabditis elegans)
MTRR:MTR [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Caenorhabditis elegans)
2xENPP1 hydrolyzes FAD to FMN (Caenorhabditis elegans)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Caenorhabditis elegans)
FMN [cytosol]
FLAD1 phosphorylates FMN (Caenorhabditis elegans)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Caenorhabditis elegans)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Caenorhabditis elegans)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Caenorhabditis elegans)
Coenzyme A biosynthesis (Caenorhabditis elegans)
3xPPCDC:3FMN decarboxylates PPC (Caenorhabditis elegans)
3xPPCDC:3xFMN [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Caenorhabditis elegans)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Caenorhabditis elegans)
2xPNPO:2xFMN [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Caenorhabditis elegans)
2xPNPO:2xFMN [cytosol] (Caenorhabditis elegans)
FMN [cytosol]
Signal Transduction (Caenorhabditis elegans)
Signaling by Nuclear Receptors (Caenorhabditis elegans)
ESR-mediated signaling (Caenorhabditis elegans)
Extra-nuclear estrogen signaling (Caenorhabditis elegans)
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by VEGF (Caenorhabditis elegans)
VEGFA-VEGFR2 Pathway (Caenorhabditis elegans)
VEGFR2 mediated vascular permeability (Caenorhabditis elegans)
AKT1 phosphorylates eNOS (Caenorhabditis elegans)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
eNOS:CaM:HSP90 [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
eNOS synthesizes NO (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
FMN [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase II - Conjugation of compounds (Canis familiaris)
Methylation (Canis familiaris)
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
MTRR:MTR:MeCbl [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Metabolism of amine-derived hormones (Canis familiaris)
Thyroxine biosynthesis (Canis familiaris)
Diiodinated tyrosine can be deiodinated (Canis familiaris)
DEHAL1:FMN [plasma membrane] (Canis familiaris)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Canis familiaris)
DEHAL1:FMN [plasma membrane] (Canis familiaris)
FMN [cytosol]
Sulfur amino acid metabolism (Canis familiaris)
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
MTRR:MTR:MeCbl [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Canis familiaris)
NOSTRIN mediated eNOS trafficking (Canis familiaris)
NOSTRIN mediated translocation of eNOS from plasma membrane (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Canis familiaris)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Canis familiaris)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Canis familiaris)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
FMN [cytosol]
Metabolism of nucleotides (Canis familiaris)
Nucleotide catabolism (Canis familiaris)
Pyrimidine catabolism (Canis familiaris)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Canis familiaris)
DPYD dimer [cytosol] (Canis familiaris)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Canis familiaris)
DPYD dimer [cytosol] (Canis familiaris)
FMN [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Canis familiaris)
Cobalamin (Cbl) metabolism (Canis familiaris)
MTR transfers CH3 from MeCbl to HCYS (Canis familiaris)
MTRR:MTR:MeCbl [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Canis familiaris)
MTRR:MTR:MeCbl [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Canis familiaris)
MTRR:MTR [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Canis familiaris)
MTRR:MTR [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Canis familiaris)
MTRR:MTR [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Canis familiaris)
2xENPP1 hydrolyzes FAD to FMN (Canis familiaris)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Canis familiaris)
FMN [cytosol]
FLAD1 phosphorylates FMN (Canis familiaris)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Canis familiaris)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Canis familiaris)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Canis familiaris)
Coenzyme A biosynthesis (Canis familiaris)
3xPPCDC:3FMN decarboxylates PPC (Canis familiaris)
3xPPCDC:3xFMN [cytosol] (Canis familiaris)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Canis familiaris)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Canis familiaris)
2xPNPO:2xFMN [cytosol] (Canis familiaris)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Canis familiaris)
2xPNPO:2xFMN [cytosol] (Canis familiaris)
FMN [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of amine-derived hormones (Danio rerio)
Thyroxine biosynthesis (Danio rerio)
Diiodinated tyrosine can be deiodinated (Danio rerio)
DEHAL1:FMN [plasma membrane] (Danio rerio)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Danio rerio)
DEHAL1:FMN [plasma membrane] (Danio rerio)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Danio rerio)
NOSTRIN mediated eNOS trafficking (Danio rerio)
NOSTRIN mediated translocation of eNOS from plasma membrane (Danio rerio)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Danio rerio)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Danio rerio)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Danio rerio)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
FMN [cytosol]
Metabolism of nucleotides (Danio rerio)
Nucleotide catabolism (Danio rerio)
Pyrimidine catabolism (Danio rerio)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Danio rerio)
DPYD dimer [cytosol] (Danio rerio)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Danio rerio)
DPYD dimer [cytosol] (Danio rerio)
FMN [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Vitamin B2 (riboflavin) metabolism (Danio rerio)
2xENPP1 hydrolyzes FAD to FMN (Danio rerio)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Danio rerio)
FMN [cytosol]
FLAD1 phosphorylates FMN (Danio rerio)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Danio rerio)
FMN [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase II - Conjugation of compounds (Dictyostelium discoideum)
Methylation (Dictyostelium discoideum)
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
MTRR:MTR:MeCbl [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Sulfur amino acid metabolism (Dictyostelium discoideum)
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
MTRR:MTR:MeCbl [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Dictyostelium discoideum)
NOSIP mediated eNOS trafficking (Dictyostelium discoideum)
eNOS binds NOSIP (Dictyostelium discoideum)
eNOS:NOSIP [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Dictyostelium discoideum)
eNOS:NOSIP [Golgi membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS activation (Dictyostelium discoideum)
AKT1 binds eNOS complex via HSP90 (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Dictyostelium discoideum)
myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
depalmitoylation of eNOS (Dictyostelium discoideum)
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide catabolism (Dictyostelium discoideum)
Pyrimidine catabolism (Dictyostelium discoideum)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Dictyostelium discoideum)
DPYD dimer [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Dictyostelium discoideum)
DPYD dimer [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of cofactors (Dictyostelium discoideum)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Dictyostelium discoideum)
BH2 binding can lead to eNOS uncoupling (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Dictyostelium discoideum)
Cobalamin (Cbl) metabolism (Dictyostelium discoideum)
MTR transfers CH3 from MeCbl to HCYS (Dictyostelium discoideum)
MTRR:MTR:MeCbl [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Dictyostelium discoideum)
MTRR:MTR:MeCbl [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Dictyostelium discoideum)
MTRR:MTR [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Dictyostelium discoideum)
2xENPP1 hydrolyzes FAD to FMN (Dictyostelium discoideum)
FMN [cytosol]
FLAD1 phosphorylates FMN (Dictyostelium discoideum)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Dictyostelium discoideum)
Coenzyme A biosynthesis (Dictyostelium discoideum)
3xPPCDC:3FMN decarboxylates PPC (Dictyostelium discoideum)
3xPPCDC:3xFMN [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Dictyostelium discoideum)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Dictyostelium discoideum)
2xPNPO:2xFMN [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Dictyostelium discoideum)
2xPNPO:2xFMN [cytosol] (Dictyostelium discoideum)
FMN [cytosol]
Signal Transduction (Dictyostelium discoideum)
Signaling by Nuclear Receptors (Dictyostelium discoideum)
ESR-mediated signaling (Dictyostelium discoideum)
Extra-nuclear estrogen signaling (Dictyostelium discoideum)
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by VEGF (Dictyostelium discoideum)
VEGFA-VEGFR2 Pathway (Dictyostelium discoideum)
VEGFR2 mediated vascular permeability (Dictyostelium discoideum)
AKT1 binds eNOS complex via HSP90 (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
AKT1 phosphorylates eNOS (Dictyostelium discoideum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
eNOS:CaM:HSP90 [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
eNOS synthesizes NO (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
FMN [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of amine-derived hormones (Drosophila melanogaster)
Thyroxine biosynthesis (Drosophila melanogaster)
Diiodinated tyrosine can be deiodinated (Drosophila melanogaster)
DEHAL1:FMN [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Drosophila melanogaster)
DEHAL1:FMN [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Drosophila melanogaster)
NOSIP mediated eNOS trafficking (Drosophila melanogaster)
eNOS binds NOSIP (Drosophila melanogaster)
eNOS:NOSIP [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Drosophila melanogaster)
eNOS:NOSIP [Golgi membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS activation (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Drosophila melanogaster)
myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
FMN [cytosol]
depalmitoylation of eNOS (Drosophila melanogaster)
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide catabolism (Drosophila melanogaster)
Pyrimidine catabolism (Drosophila melanogaster)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Drosophila melanogaster)
DPYD dimer [cytosol] (Drosophila melanogaster)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Drosophila melanogaster)
DPYD dimer [cytosol] (Drosophila melanogaster)
FMN [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of cofactors (Drosophila melanogaster)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Drosophila melanogaster)
BH2 binding can lead to eNOS uncoupling (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Vitamin B2 (riboflavin) metabolism (Drosophila melanogaster)
FLAD1 phosphorylates FMN (Drosophila melanogaster)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Drosophila melanogaster)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Drosophila melanogaster)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Drosophila melanogaster)
Coenzyme A biosynthesis (Drosophila melanogaster)
3xPPCDC:3FMN decarboxylates PPC (Drosophila melanogaster)
3xPPCDC:3xFMN [cytosol] (Drosophila melanogaster)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Drosophila melanogaster)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Drosophila melanogaster)
2xPNPO:2xFMN [cytosol] (Drosophila melanogaster)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Drosophila melanogaster)
2xPNPO:2xFMN [cytosol] (Drosophila melanogaster)
FMN [cytosol]
Signal Transduction (Drosophila melanogaster)
Signaling by Nuclear Receptors (Drosophila melanogaster)
ESR-mediated signaling (Drosophila melanogaster)
Extra-nuclear estrogen signaling (Drosophila melanogaster)
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by VEGF (Drosophila melanogaster)
VEGFA-VEGFR2 Pathway (Drosophila melanogaster)
VEGFR2 mediated vascular permeability (Drosophila melanogaster)
AKT1 binds eNOS complex via HSP90 (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
AKT1 phosphorylates eNOS (Drosophila melanogaster)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
eNOS:CaM:HSP90 [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
eNOS synthesizes NO (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
FMN [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase II - Conjugation of compounds (Gallus gallus)
Methylation (Gallus gallus)
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
MTRR:MTR:MeCbl [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Thyroxine biosynthesis (Gallus gallus)
Diiodinated tyrosine can be deiodinated (Gallus gallus)
DEHAL1:FMN [plasma membrane] (Gallus gallus)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Gallus gallus)
DEHAL1:FMN [plasma membrane] (Gallus gallus)
FMN [cytosol]
Sulfur amino acid metabolism (Gallus gallus)
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
MTRR:MTR:MeCbl [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Gallus gallus)
NOSTRIN mediated eNOS trafficking (Gallus gallus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Gallus gallus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Gallus gallus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Gallus gallus)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS activation (Gallus gallus)
AKT1 binds eNOS complex via HSP90 (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Gallus gallus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Gallus gallus)
myristoylated eNOS dimer [Golgi membrane] (Gallus gallus)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Gallus gallus)
FMN [cytosol]
depalmitoylation of eNOS (Gallus gallus)
myristoylated eNOS dimer [cytosol] (Gallus gallus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS associates with Caveolin-1 (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Metabolism of nucleotides (Gallus gallus)
Nucleotide catabolism (Gallus gallus)
Pyrimidine catabolism (Gallus gallus)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Gallus gallus)
DPYD dimer [cytosol] (Gallus gallus)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Gallus gallus)
DPYD dimer [cytosol] (Gallus gallus)
FMN [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of cofactors (Gallus gallus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Gallus gallus)
BH2 binding can lead to eNOS uncoupling (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Gallus gallus)
Cobalamin (Cbl) metabolism (Gallus gallus)
MTR transfers CH3 from MeCbl to HCYS (Gallus gallus)
MTRR:MTR:MeCbl [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Gallus gallus)
MTRR:MTR:MeCbl [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Gallus gallus)
MTRR:MTR [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Gallus gallus)
MTRR:MTR [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Gallus gallus)
MTRR:MTR [cytosol] (Gallus gallus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Gallus gallus)
2xTRAP hydrolyzes FMN to RIB (Gallus gallus)
FMN [cytosol]
FLAD1 phosphorylates FMN (Gallus gallus)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Gallus gallus)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Gallus gallus)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Gallus gallus)
Coenzyme A biosynthesis (Gallus gallus)
3xPPCDC:3FMN decarboxylates PPC (Gallus gallus)
3xPPCDC:3xFMN [cytosol] (Gallus gallus)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Gallus gallus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Gallus gallus)
2xPNPO:2xFMN [cytosol] (Gallus gallus)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Gallus gallus)
2xPNPO:2xFMN [cytosol] (Gallus gallus)
FMN [cytosol]
Signal Transduction (Gallus gallus)
Signaling by Nuclear Receptors (Gallus gallus)
ESR-mediated signaling (Gallus gallus)
Extra-nuclear estrogen signaling (Gallus gallus)
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by VEGF (Gallus gallus)
VEGFA-VEGFR2 Pathway (Gallus gallus)
VEGFR2 mediated vascular permeability (Gallus gallus)
AKT1 binds eNOS complex via HSP90 (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Gallus gallus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Gallus gallus)
eNOS:CaM:HSP90 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Gallus gallus)
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS synthesizes NO (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Gallus gallus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Gallus gallus)
eNOS:Caveolin-1 [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
FMN [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Defects in vitamin and cofactor metabolism (Homo sapiens)
Defects in cobalamin (B12) metabolism (Homo sapiens)
Defective MTR causes HMAG (Homo sapiens)
Defective MTR does not transfer CH3 group from MTHF to cob(I)alamin (Homo sapiens)
MTRR:mutant MTR(cob(I)alamin) [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Defective MTR does not transfer CH3 group from MeCbl to HCYS (Homo sapiens)
MTRR:mutant MTR(MeCbl) [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Defective MTRR causes HMAE (Homo sapiens)
Defective MTRR does not convert cob(II)alamin to MeCbl (Homo sapiens)
mutant MTRR:MTR(cob(II)alamin) [cytosol] (Homo sapiens)
mutant MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase II - Conjugation of compounds (Homo sapiens)
Methylation (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
MTRR:MTR:MeCbl [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Cytosolic iron-sulfur cluster assembly (Homo sapiens)
4Fe-4S cluster assembles on NUBP2:NUBP1 scaffold (Homo sapiens)
NDOR1:CIAPIN1 reduced [cytosol] (Homo sapiens)
NDOR1:FAD:FMN [cytosol] (Homo sapiens)
FMN [cytosol]
NADPH reduces NDOR1:CIAPIN1 (Homo sapiens)
NDOR1:CIAPIN1 oxidized [cytosol] (Homo sapiens)
NDOR1:FAD:FMN [cytosol] (Homo sapiens)
FMN [cytosol]
NDOR1:CIAPIN1 reduced [cytosol] (Homo sapiens)
NDOR1:FAD:FMN [cytosol] (Homo sapiens)
FMN [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Metabolism of amine-derived hormones (Homo sapiens)
Thyroxine biosynthesis (Homo sapiens)
Diiodinated tyrosine can be deiodinated (Homo sapiens)
DEHAL1:FMN [plasma membrane] (Homo sapiens)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Homo sapiens)
DEHAL1:FMN [plasma membrane] (Homo sapiens)
FMN [cytosol]
Sulfur amino acid metabolism (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
MTRR:MTR:MeCbl [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Homo sapiens)
NOSIP mediated eNOS trafficking (Homo sapiens)
eNOS binds NOSIP (Homo sapiens)
eNOS:NOSIP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Homo sapiens)
eNOS:NOSIP [Golgi membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
NOSTRIN mediated eNOS trafficking (Homo sapiens)
NOSTRIN mediated translocation of eNOS from plasma membrane (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Homo sapiens)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Homo sapiens)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS activation (Homo sapiens)
AKT1 binds eNOS complex via HSP90 (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
AKT1 phosphorylates eNOS (Homo sapiens)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Homo sapiens)
FMN [cytosol]
depalmitoylation of eNOS (Homo sapiens)
myristoylated eNOS dimer [cytosol] (Homo sapiens)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS associates with Caveolin-1 (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Pyrimidine catabolism (Homo sapiens)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Homo sapiens)
DPYD dimer [cytosol] (Homo sapiens)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Homo sapiens)
DPYD dimer [cytosol] (Homo sapiens)
FMN [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of cofactors (Homo sapiens)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Homo sapiens)
BH2 binding can lead to eNOS uncoupling (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Homo sapiens)
Cobalamin (Cbl) metabolism (Homo sapiens)
MTR transfers CH3 from MeCbl to HCYS (Homo sapiens)
MTRR:MTR:MeCbl [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Homo sapiens)
MTRR:MTR:MeCbl [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Homo sapiens)
MTRR:MTR [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Homo sapiens)
MTRR:MTR [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Homo sapiens)
MTRR:MTR [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Homo sapiens)
2xENPP1 hydrolyzes FAD to FMN (Homo sapiens)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Homo sapiens)
FMN [cytosol]
FLAD1 phosphorylates FMN (Homo sapiens)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Homo sapiens)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Homo sapiens)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Homo sapiens)
Coenzyme A biosynthesis (Homo sapiens)
3xPPCDC:3FMN decarboxylates PPC (Homo sapiens)
3xPPCDC:3xFMN [cytosol] (Homo sapiens)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Homo sapiens)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Homo sapiens)
2xPNPO:2xFMN [cytosol] (Homo sapiens)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Homo sapiens)
2xPNPO:2xFMN [cytosol] (Homo sapiens)
FMN [cytosol]
Signal Transduction (Homo sapiens)
Signaling by Nuclear Receptors (Homo sapiens)
ESR-mediated signaling (Homo sapiens)
Extra-nuclear estrogen signaling (Homo sapiens)
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by VEGF (Homo sapiens)
VEGFA-VEGFR2 Pathway (Homo sapiens)
VEGFR2 mediated vascular permeability (Homo sapiens)
AKT1 binds eNOS complex via HSP90 (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
AKT1 phosphorylates eNOS (Homo sapiens)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Homo sapiens)
eNOS:CaM:HSP90 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Homo sapiens)
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS synthesizes NO (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Homo sapiens)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Homo sapiens)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Homo sapiens)
eNOS:Caveolin-1 [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
FMN [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase II - Conjugation of compounds (Mus musculus)
Methylation (Mus musculus)
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
MTRR:MTR:MeCbl [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Metabolism of amine-derived hormones (Mus musculus)
Thyroxine biosynthesis (Mus musculus)
Diiodinated tyrosine can be deiodinated (Mus musculus)
DEHAL1:FMN [plasma membrane] (Mus musculus)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Mus musculus)
DEHAL1:FMN [plasma membrane] (Mus musculus)
FMN [cytosol]
Sulfur amino acid metabolism (Mus musculus)
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
MTRR:MTR:MeCbl [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Mus musculus)
NOSIP mediated eNOS trafficking (Mus musculus)
eNOS binds NOSIP (Mus musculus)
eNOS:NOSIP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Mus musculus)
eNOS:NOSIP [Golgi membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
NOSTRIN mediated eNOS trafficking (Mus musculus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Mus musculus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Mus musculus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Mus musculus)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS activation (Mus musculus)
AKT1 binds eNOS complex via HSP90 (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Mus musculus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Mus musculus)
myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Mus musculus)
FMN [cytosol]
depalmitoylation of eNOS (Mus musculus)
myristoylated eNOS dimer [cytosol] (Mus musculus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS associates with Caveolin-1 (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Metabolism of nucleotides (Mus musculus)
Nucleotide catabolism (Mus musculus)
Pyrimidine catabolism (Mus musculus)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Mus musculus)
DPYD dimer [cytosol] (Mus musculus)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Mus musculus)
DPYD dimer [cytosol] (Mus musculus)
FMN [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of cofactors (Mus musculus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Mus musculus)
BH2 binding can lead to eNOS uncoupling (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Mus musculus)
Cobalamin (Cbl) metabolism (Mus musculus)
MTR transfers CH3 from MeCbl to HCYS (Mus musculus)
MTRR:MTR:MeCbl [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Mus musculus)
MTRR:MTR:MeCbl [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Mus musculus)
MTRR:MTR [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Mus musculus)
MTRR:MTR [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Mus musculus)
MTRR:MTR [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Mus musculus)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Mus musculus)
2xENPP1 hydrolyzes FAD to FMN (Mus musculus)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Mus musculus)
FMN [cytosol]
FLAD1 phosphorylates FMN (Mus musculus)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Mus musculus)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Mus musculus)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Mus musculus)
Coenzyme A biosynthesis (Mus musculus)
3xPPCDC:3FMN decarboxylates PPC (Mus musculus)
3xPPCDC:3xFMN [cytosol] (Mus musculus)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Mus musculus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Mus musculus)
2xPNPO:2xFMN [cytosol] (Mus musculus)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Mus musculus)
2xPNPO:2xFMN [cytosol] (Mus musculus)
FMN [cytosol]
Signal Transduction (Mus musculus)
Signaling by Nuclear Receptors (Mus musculus)
ESR-mediated signaling (Mus musculus)
Extra-nuclear estrogen signaling (Mus musculus)
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by VEGF (Mus musculus)
VEGFA-VEGFR2 Pathway (Mus musculus)
VEGFR2 mediated vascular permeability (Mus musculus)
AKT1 binds eNOS complex via HSP90 (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Mus musculus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Mus musculus)
eNOS:CaM:HSP90 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Mus musculus)
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS synthesizes NO (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Mus musculus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Mus musculus)
eNOS:Caveolin-1 [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
FMN [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Chorismate via Shikimate Pathway (Mycobacterium tuberculosis)
Dephosphorylation of EPSP yields chorismate (Mycobacterium tuberculosis)
AroC-FMN [cytosol] (Mycobacterium tuberculosis)
FMN [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nitric oxide: NOS3 activation and regulation (Plasmodium falciparum)
NOSIP mediated eNOS trafficking (Plasmodium falciparum)
eNOS binds NOSIP (Plasmodium falciparum)
eNOS:NOSIP [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Plasmodium falciparum)
eNOS:NOSIP [Golgi membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
eNOS activation (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
eNOS:CaM:HSP90 [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Plasmodium falciparum)
myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Plasmodium falciparum)
FMN [cytosol]
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of cofactors (Plasmodium falciparum)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Plasmodium falciparum)
BH2 binding can lead to eNOS uncoupling (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Plasmodium falciparum)
Vitamin B2 (riboflavin) metabolism (Plasmodium falciparum)
2xTRAP hydrolyzes FMN to RIB (Plasmodium falciparum)
FMN [cytosol]
FLAD1 phosphorylates FMN (Plasmodium falciparum)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Plasmodium falciparum)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Plasmodium falciparum)
Coenzyme A biosynthesis (Plasmodium falciparum)
3xPPCDC:3FMN decarboxylates PPC (Plasmodium falciparum)
3xPPCDC:3xFMN [cytosol] (Plasmodium falciparum)
FMN [cytosol]
Signal Transduction (Plasmodium falciparum)
Signaling by Nuclear Receptors (Plasmodium falciparum)
ESR-mediated signaling (Plasmodium falciparum)
Extra-nuclear estrogen signaling (Plasmodium falciparum)
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by VEGF (Plasmodium falciparum)
VEGFA-VEGFR2 Pathway (Plasmodium falciparum)
VEGFR2 mediated vascular permeability (Plasmodium falciparum)
AKT1 phosphorylates eNOS (Plasmodium falciparum)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
eNOS:CaM:HSP90 [plasma membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
eNOS synthesizes NO (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
FMN [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase II - Conjugation of compounds (Rattus norvegicus)
Methylation (Rattus norvegicus)
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
MTRR:MTR:MeCbl [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Metabolism of amine-derived hormones (Rattus norvegicus)
Thyroxine biosynthesis (Rattus norvegicus)
Diiodinated tyrosine can be deiodinated (Rattus norvegicus)
DEHAL1:FMN [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Rattus norvegicus)
DEHAL1:FMN [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Sulfur amino acid metabolism (Rattus norvegicus)
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
MTRR:MTR:MeCbl [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Rattus norvegicus)
NOSIP mediated eNOS trafficking (Rattus norvegicus)
eNOS binds NOSIP (Rattus norvegicus)
eNOS:NOSIP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Rattus norvegicus)
eNOS:NOSIP [Golgi membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
NOSTRIN mediated eNOS trafficking (Rattus norvegicus)
NOSTRIN mediated translocation of eNOS from plasma membrane (Rattus norvegicus)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Rattus norvegicus)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS activation (Rattus norvegicus)
AKT1 binds eNOS complex via HSP90 (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Rattus norvegicus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Rattus norvegicus)
myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
FMN [cytosol]
depalmitoylation of eNOS (Rattus norvegicus)
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS associates with Caveolin-1 (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide catabolism (Rattus norvegicus)
Pyrimidine catabolism (Rattus norvegicus)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Rattus norvegicus)
DPYD dimer [cytosol] (Rattus norvegicus)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Rattus norvegicus)
DPYD dimer [cytosol] (Rattus norvegicus)
FMN [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of cofactors (Rattus norvegicus)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Rattus norvegicus)
BH2 binding can lead to eNOS uncoupling (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Rattus norvegicus)
Cobalamin (Cbl) metabolism (Rattus norvegicus)
MTR transfers CH3 from MeCbl to HCYS (Rattus norvegicus)
MTRR:MTR:MeCbl [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Rattus norvegicus)
MTRR:MTR:MeCbl [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Rattus norvegicus)
MTRR:MTR [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Rattus norvegicus)
MTRR:MTR [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Rattus norvegicus)
MTRR:MTR [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Rattus norvegicus)
2xENPP1 hydrolyzes FAD to FMN (Rattus norvegicus)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Rattus norvegicus)
FMN [cytosol]
FLAD1 phosphorylates FMN (Rattus norvegicus)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Rattus norvegicus)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Rattus norvegicus)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Rattus norvegicus)
Coenzyme A biosynthesis (Rattus norvegicus)
3xPPCDC:3FMN decarboxylates PPC (Rattus norvegicus)
3xPPCDC:3xFMN [cytosol] (Rattus norvegicus)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Rattus norvegicus)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Rattus norvegicus)
2xPNPO:2xFMN [cytosol] (Rattus norvegicus)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Rattus norvegicus)
2xPNPO:2xFMN [cytosol] (Rattus norvegicus)
FMN [cytosol]
Signal Transduction (Rattus norvegicus)
Signaling by Nuclear Receptors (Rattus norvegicus)
ESR-mediated signaling (Rattus norvegicus)
Extra-nuclear estrogen signaling (Rattus norvegicus)
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by VEGF (Rattus norvegicus)
VEGFA-VEGFR2 Pathway (Rattus norvegicus)
VEGFR2 mediated vascular permeability (Rattus norvegicus)
AKT1 binds eNOS complex via HSP90 (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
AKT1 phosphorylates eNOS (Rattus norvegicus)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Rattus norvegicus)
eNOS:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Rattus norvegicus)
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS synthesizes NO (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Rattus norvegicus)
eNOS:Caveolin-1 [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
FMN [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nitric oxide: NOS3 activation and regulation (Saccharomyces cerevisiae)
eNOS activation (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Saccharomyces cerevisiae)
myristoylated eNOS dimer [Golgi membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
FMN [cytosol]
depalmitoylation of eNOS (Saccharomyces cerevisiae)
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of cofactors (Saccharomyces cerevisiae)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Saccharomyces cerevisiae)
BH2 binding can lead to eNOS uncoupling (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Vitamin B2 (riboflavin) metabolism (Saccharomyces cerevisiae)
2xENPP1 hydrolyzes FAD to FMN (Saccharomyces cerevisiae)
FMN [cytosol]
FLAD1 phosphorylates FMN (Saccharomyces cerevisiae)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Saccharomyces cerevisiae)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Saccharomyces cerevisiae)
Coenzyme A biosynthesis (Saccharomyces cerevisiae)
3xPPCDC:3FMN decarboxylates PPC (Saccharomyces cerevisiae)
3xPPCDC:3xFMN [cytosol] (Saccharomyces cerevisiae)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Saccharomyces cerevisiae)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Saccharomyces cerevisiae)
2xPNPO:2xFMN [cytosol] (Saccharomyces cerevisiae)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Saccharomyces cerevisiae)
2xPNPO:2xFMN [cytosol] (Saccharomyces cerevisiae)
FMN [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Nuclear Receptors (Saccharomyces cerevisiae)
ESR-mediated signaling (Saccharomyces cerevisiae)
Extra-nuclear estrogen signaling (Saccharomyces cerevisiae)
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by VEGF (Saccharomyces cerevisiae)
VEGFA-VEGFR2 Pathway (Saccharomyces cerevisiae)
VEGFR2 mediated vascular permeability (Saccharomyces cerevisiae)
AKT1 phosphorylates eNOS (Saccharomyces cerevisiae)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
eNOS:CaM:HSP90 [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
eNOS synthesizes NO (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
FMN [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nitric oxide: NOS3 activation and regulation (Schizosaccharomyces pombe)
eNOS activation (Schizosaccharomyces pombe)
AKT1 binds eNOS complex via HSP90 (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Schizosaccharomyces pombe)
myristoylated eNOS dimer [Golgi membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
FMN [cytosol]
depalmitoylation of eNOS (Schizosaccharomyces pombe)
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of cofactors (Schizosaccharomyces pombe)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Schizosaccharomyces pombe)
BH2 binding can lead to eNOS uncoupling (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Vitamin B2 (riboflavin) metabolism (Schizosaccharomyces pombe)
2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)
FMN [cytosol]
FLAD1 phosphorylates FMN (Schizosaccharomyces pombe)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Schizosaccharomyces pombe)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Schizosaccharomyces pombe)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Schizosaccharomyces pombe)
2xPNPO:2xFMN [cytosol] (Schizosaccharomyces pombe)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Schizosaccharomyces pombe)
2xPNPO:2xFMN [cytosol] (Schizosaccharomyces pombe)
FMN [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Nuclear Receptors (Schizosaccharomyces pombe)
ESR-mediated signaling (Schizosaccharomyces pombe)
Extra-nuclear estrogen signaling (Schizosaccharomyces pombe)
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
Signaling by VEGF (Schizosaccharomyces pombe)
VEGFA-VEGFR2 Pathway (Schizosaccharomyces pombe)
VEGFR2 mediated vascular permeability (Schizosaccharomyces pombe)
AKT1 binds eNOS complex via HSP90 (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
AKT1 phosphorylates eNOS (Schizosaccharomyces pombe)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
eNOS:CaM:HSP90 [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
eNOS synthesizes NO (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
FMN [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase II - Conjugation of compounds (Sus scrofa)
Methylation (Sus scrofa)
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
MTRR:MTR:MeCbl [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Metabolism of amine-derived hormones (Sus scrofa)
Thyroxine biosynthesis (Sus scrofa)
Diiodinated tyrosine can be deiodinated (Sus scrofa)
DEHAL1:FMN [plasma membrane] (Sus scrofa)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Sus scrofa)
DEHAL1:FMN [plasma membrane] (Sus scrofa)
FMN [cytosol]
Sulfur amino acid metabolism (Sus scrofa)
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
MTRR:MTR:MeCbl [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
Metabolism of nitric oxide: NOS3 activation and regulation (Sus scrofa)
NOSIP mediated eNOS trafficking (Sus scrofa)
eNOS binds NOSIP (Sus scrofa)
eNOS:NOSIP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:NOSIP translocation from caveolae to intracellular compartments (Sus scrofa)
eNOS:NOSIP [Golgi membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
FMN [cytosol]
eNOS:NOSIP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
NOSTRIN mediated eNOS trafficking (Sus scrofa)
NOSTRIN mediated translocation of eNOS from plasma membrane (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [endocytic vesicle membrane] (Sus scrofa)
eNOS:Caveolin-1 [endocytic vesicle membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to Nostrin (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN complex binds dynamin-2 (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN complex [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2 complex binds N-WASP (Sus scrofa)
eNOS:Caveolin-1:NOSTRIN:Dynamin-2 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:NOSTRIN:dynamin-2:N-WASP [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS activation (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
BH2 binding can lead to eNOS uncoupling (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Uncoupled eNOS favours the formation of superoxide (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
depalmitoylated eNOS translocates from plasma membrane (Sus scrofa)
myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
FMN [cytosol]
myristoylated eNOS dimer [cytosol] (Sus scrofa)
FMN [cytosol]
depalmitoylation of eNOS (Sus scrofa)
myristoylated eNOS dimer [cytosol] (Sus scrofa)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS associates with Caveolin-1 (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS translocation from Golgi to Caveolae (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Metabolism of nucleotides (Sus scrofa)
Nucleotide catabolism (Sus scrofa)
Pyrimidine catabolism (Sus scrofa)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Sus scrofa)
DPYD dimer [cytosol] (Sus scrofa)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Sus scrofa)
DPYD dimer [cytosol] (Sus scrofa)
FMN [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of cofactors (Sus scrofa)
Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation (Sus scrofa)
BH2 binding can lead to eNOS uncoupling (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH2 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Cobalamin (Cbl, vitamin B12) transport and metabolism (Sus scrofa)
Cobalamin (Cbl) metabolism (Sus scrofa)
MTR transfers CH3 from MeCbl to HCYS (Sus scrofa)
MTRR:MTR:MeCbl [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTR transfers CH3 group from 5-methyl-THF to cob(I)alamin (Sus scrofa)
MTRR:MTR:MeCbl [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(I)alamin [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR reduces cob(II)alamin to meCbl (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:MeCbl [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Sus scrofa)
MTRR:MTR [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
cob(II)alamin is transferred from MMACHC:MMADHC:cob(II)alamin to MTRR:MTR (Sus scrofa)
MTRR:MTR [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
MTRR:MTR:cob(II)alamin [cytosol] (Sus scrofa)
MTRR:MTR [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
FMN [cytosol]
Vitamin B2 (riboflavin) metabolism (Sus scrofa)
2xENPP1 hydrolyzes FAD to FMN (Sus scrofa)
FMN [cytosol]
2xTRAP hydrolyzes FMN to RIB (Sus scrofa)
FMN [cytosol]
FLAD1 phosphorylates FMN (Sus scrofa)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Sus scrofa)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Sus scrofa)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Sus scrofa)
Coenzyme A biosynthesis (Sus scrofa)
3xPPCDC:3FMN decarboxylates PPC (Sus scrofa)
3xPPCDC:3xFMN [cytosol] (Sus scrofa)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Sus scrofa)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Sus scrofa)
2xPNPO:2xFMN [cytosol] (Sus scrofa)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Sus scrofa)
2xPNPO:2xFMN [cytosol] (Sus scrofa)
FMN [cytosol]
Signal Transduction (Sus scrofa)
Signaling by Nuclear Receptors (Sus scrofa)
ESR-mediated signaling (Sus scrofa)
Extra-nuclear estrogen signaling (Sus scrofa)
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by VEGF (Sus scrofa)
VEGFA-VEGFR2 Pathway (Sus scrofa)
VEGFR2 mediated vascular permeability (Sus scrofa)
AKT1 phosphorylates eNOS (Sus scrofa)
eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Caveolin-1 dissociates from eNOS:CaM:HSP90 complex (Sus scrofa)
eNOS:CaM:HSP90 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
HSP90 binds eNOS:Caveolin-1:CaM complex (Sus scrofa)
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM:HSP90 [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
The cofactor BH4 is required for electron transfer in the eNOS catalytic cycle (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS synthesizes NO (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1:BH4 [plasma membrane] (Sus scrofa)
p-S1177-eNOS:CaM:HSP90:p-AKT1 [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1 complex binds to CaM (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
eNOS:Caveolin-1:CaM [plasma membrane] (Sus scrofa)
eNOS:Caveolin-1 [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
FMN [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Metabolism of amine-derived hormones (Xenopus tropicalis)
Thyroxine biosynthesis (Xenopus tropicalis)
Diiodinated tyrosine can be deiodinated (Xenopus tropicalis)
DEHAL1:FMN [plasma membrane] (Xenopus tropicalis)
FMN [cytosol]
Monoiodinated tyrosine can be deiodinated (Xenopus tropicalis)
DEHAL1:FMN [plasma membrane] (Xenopus tropicalis)
FMN [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide catabolism (Xenopus tropicalis)
Pyrimidine catabolism (Xenopus tropicalis)
thymine + NADPH + H+ => 5,6-dihydrothymine + NADP+ (Xenopus tropicalis)
DPYD dimer [cytosol] (Xenopus tropicalis)
FMN [cytosol]
uracil + NADPH + H+ => 5,6-dihydrouracil + NADP+ (Xenopus tropicalis)
DPYD dimer [cytosol] (Xenopus tropicalis)
FMN [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Vitamin B2 (riboflavin) metabolism (Xenopus tropicalis)
2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)
FMN [cytosol]
RFK:Mg2+ phosphorylates RIB (Xenopus tropicalis)
FMN [cytosol]
SLC52A1,2,3 transport RIB from extracellular region to cytosol (Xenopus tropicalis)
FMN [cytosol]
Vitamin B5 (pantothenate) metabolism (Xenopus tropicalis)
Coenzyme A biosynthesis (Xenopus tropicalis)
3xPPCDC:3FMN decarboxylates PPC (Xenopus tropicalis)
3xPPCDC:3xFMN [cytosol] (Xenopus tropicalis)
FMN [cytosol]
Vitamin B6 activation to pyridoxal phosphate (Xenopus tropicalis)
2xPNPO:2xFMN oxidizes PDXP to PXLP (Xenopus tropicalis)
2xPNPO:2xFMN [cytosol] (Xenopus tropicalis)
FMN [cytosol]
2xPNPO:2xFMN oxidizes PXAP to PXLP (Xenopus tropicalis)
2xPNPO:2xFMN [cytosol] (Xenopus tropicalis)
FMN [cytosol]
External Reference Information
External Reference
FMN(3-) [ChEBI:58210]
Participates
as a component of
AroC-FMN [cytosol] (Mycobacterium tuberculosis)
TAH18:FAD:FMN [cytosol] (Saccharomyces cerevisiae)
NDOR1:FAD:FMN [cytosol] (Homo sapiens)
mutant MTRR:FMN:FAD [cytosol] (Homo sapiens)
3xPPCDC:3xFMN [cytosol] (Drosophila melanogaster)
3xPPCDC:3xFMN [cytosol] (Mus musculus)
3xPPCDC:3xFMN [cytosol] (Plasmodium falciparum)
3xPPCDC:3xFMN [cytosol] (Gallus gallus)
3xPPCDC:3xFMN [cytosol] (Saccharomyces cerevisiae)
3xPPCDC:3xFMN [cytosol] (Sus scrofa)
3xPPCDC:3xFMN [cytosol] (Caenorhabditis elegans)
3xPPCDC:3xFMN [cytosol] (Rattus norvegicus)
3xPPCDC:3xFMN [cytosol] (Xenopus tropicalis)
3xPPCDC:3xFMN [cytosol] (Bos taurus)
3xPPCDC:3xFMN [cytosol] (Dictyostelium discoideum)
3xPPCDC:3xFMN [cytosol] (Canis familiaris)
3xPPCDC:3xFMN [cytosol] (Homo sapiens)
2xPNPO:2xFMN [cytosol] (Drosophila melanogaster)
2xPNPO:2xFMN [cytosol] (Gallus gallus)
2xPNPO:2xFMN [cytosol] (Xenopus tropicalis)
2xPNPO:2xFMN [cytosol] (Canis familiaris)
2xPNPO:2xFMN [cytosol] (Bos taurus)
2xPNPO:2xFMN [cytosol] (Rattus norvegicus)
2xPNPO:2xFMN [cytosol] (Caenorhabditis elegans)
2xPNPO:2xFMN [cytosol] (Sus scrofa)
2xPNPO:2xFMN [cytosol] (Mus musculus)
2xPNPO:2xFMN [cytosol] (Saccharomyces cerevisiae)
2xPNPO:2xFMN [cytosol] (Schizosaccharomyces pombe)
2xPNPO:2xFMN [cytosol] (Dictyostelium discoideum)
2xPNPO:2xFMN [cytosol] (Homo sapiens)
DEHAL1:FMN [plasma membrane] (Mus musculus)
DEHAL1:FMN [plasma membrane] (Drosophila melanogaster)
DEHAL1:FMN [plasma membrane] (Xenopus tropicalis)
DEHAL1:FMN [plasma membrane] (Danio rerio)
DEHAL1:FMN [plasma membrane] (Caenorhabditis elegans)
DEHAL1:FMN [plasma membrane] (Gallus gallus)
DEHAL1:FMN [plasma membrane] (Sus scrofa)
DEHAL1:FMN [plasma membrane] (Bos taurus)
DEHAL1:FMN [plasma membrane] (Rattus norvegicus)
DEHAL1:FMN [plasma membrane] (Canis familiaris)
DEHAL1:FMN [plasma membrane] (Homo sapiens)
DPYD dimer [cytosol] (Caenorhabditis elegans)
DPYD dimer [cytosol] (Bos taurus)
DPYD dimer [cytosol] (Dictyostelium discoideum)
DPYD dimer [cytosol] (Sus scrofa)
DPYD dimer [cytosol] (Drosophila melanogaster)
DPYD dimer [cytosol] (Mus musculus)
DPYD dimer [cytosol] (Canis familiaris)
DPYD dimer [cytosol] (Gallus gallus)
DPYD dimer [cytosol] (Xenopus tropicalis)
DPYD dimer [cytosol] (Danio rerio)
DPYD dimer [cytosol] (Rattus norvegicus)
DPYD dimer [cytosol] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [endocytic vesicle membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
p-S1177-eNOS dimer [plasma membrane] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Sus scrofa)
p-S1177-eNOS dimer [plasma membrane] (Caenorhabditis elegans)
p-S1177-eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
p-S1177-eNOS dimer [plasma membrane] (Plasmodium falciparum)
p-S1177-eNOS dimer [plasma membrane] (Bos taurus)
p-S1177-eNOS dimer [plasma membrane] (Mus musculus)
p-S1177-eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
p-S1177-eNOS dimer [plasma membrane] (Dictyostelium discoideum)
p-S1177-eNOS dimer [plasma membrane] (Rattus norvegicus)
p-S1177-eNOS dimer [plasma membrane] (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Homo sapiens)
MTRR:FMN:FAD [cytosol] (Caenorhabditis elegans)
MTRR:FMN:FAD [cytosol] (Dictyostelium discoideum)
MTRR:FMN:FAD [cytosol] (Mus musculus)
MTRR:FMN:FAD [cytosol] (Canis familiaris)
MTRR:FMN:FAD [cytosol] (Bos taurus)
MTRR:FMN:FAD [cytosol] (Sus scrofa)
MTRR:FMN:FAD [cytosol] (Rattus norvegicus)
MTRR:FMN:FAD [cytosol] (Gallus gallus)
p-S1177-eNOS dimer [plasma membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Drosophila melanogaster)
myristoylated eNOS dimer [cytosol] (Drosophila melanogaster)
myristoylated eNOS dimer [Golgi membrane] (Drosophila melanogaster)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Homo sapiens)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Rattus norvegicus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Bos taurus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Dictyostelium discoideum)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Mus musculus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Canis familiaris)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Danio rerio)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Schizosaccharomyces pombe)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Caenorhabditis elegans)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Sus scrofa)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Saccharomyces cerevisiae)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Gallus gallus)
palmitoylated, myristoylated eNOS dimer [plasma membrane] (Plasmodium falciparum)
myristoylated eNOS dimer [cytosol] (Homo sapiens)
myristoylated eNOS dimer [cytosol] (Dictyostelium discoideum)
myristoylated eNOS dimer [cytosol] (Rattus norvegicus)
myristoylated eNOS dimer [cytosol] (Saccharomyces cerevisiae)
myristoylated eNOS dimer [cytosol] (Mus musculus)
myristoylated eNOS dimer [cytosol] (Plasmodium falciparum)
myristoylated eNOS dimer [cytosol] (Bos taurus)
myristoylated eNOS dimer [cytosol] (Sus scrofa)
myristoylated eNOS dimer [cytosol] (Gallus gallus)
myristoylated eNOS dimer [cytosol] (Schizosaccharomyces pombe)
myristoylated eNOS dimer [Golgi membrane] (Homo sapiens)
myristoylated eNOS dimer [Golgi membrane] (Saccharomyces cerevisiae)
myristoylated eNOS dimer [Golgi membrane] (Mus musculus)
myristoylated eNOS dimer [Golgi membrane] (Gallus gallus)
myristoylated eNOS dimer [Golgi membrane] (Plasmodium falciparum)
myristoylated eNOS dimer [Golgi membrane] (Rattus norvegicus)
myristoylated eNOS dimer [Golgi membrane] (Sus scrofa)
myristoylated eNOS dimer [Golgi membrane] (Schizosaccharomyces pombe)
myristoylated eNOS dimer [Golgi membrane] (Dictyostelium discoideum)
as an input of
FLAD1 phosphorylates FMN (Plasmodium falciparum)
FLAD1 phosphorylates FMN (Drosophila melanogaster)
FLAD1 phosphorylates FMN (Gallus gallus)
2xTRAP hydrolyzes FMN to RIB (Plasmodium falciparum)
2xTRAP hydrolyzes FMN to RIB (Gallus gallus)
2xTRAP hydrolyzes FMN to RIB (Danio rerio)
FLAD1 phosphorylates FMN (Saccharomyces cerevisiae)
FLAD1 phosphorylates FMN (Schizosaccharomyces pombe)
FLAD1 phosphorylates FMN (Dictyostelium discoideum)
2xTRAP hydrolyzes FMN to RIB (Caenorhabditis elegans)
FLAD1 phosphorylates FMN (Caenorhabditis elegans)
FLAD1 phosphorylates FMN (Danio rerio)
2xTRAP hydrolyzes FMN to RIB (Sus scrofa)
FLAD1 phosphorylates FMN (Sus scrofa)
2xTRAP hydrolyzes FMN to RIB (Bos taurus)
FLAD1 phosphorylates FMN (Bos taurus)
2xTRAP hydrolyzes FMN to RIB (Canis familiaris)
FLAD1 phosphorylates FMN (Canis familiaris)
2xTRAP hydrolyzes FMN to RIB (Rattus norvegicus)
FLAD1 phosphorylates FMN (Rattus norvegicus)
2xTRAP hydrolyzes FMN to RIB (Mus musculus)
FLAD1 phosphorylates FMN (Mus musculus)
2xTRAP hydrolyzes FMN to RIB (Homo sapiens)
FLAD1 phosphorylates FMN (Homo sapiens)
as an output of
RFK:Mg2+ phosphorylates RIB (Plasmodium falciparum)
RFK:Mg2+ phosphorylates RIB (Drosophila melanogaster)
RFK:Mg2+ phosphorylates RIB (Gallus gallus)
RFK:Mg2+ phosphorylates RIB (Xenopus tropicalis)
RFK:Mg2+ phosphorylates RIB (Saccharomyces cerevisiae)
2xENPP1 hydrolyzes FAD to FMN (Saccharomyces cerevisiae)
RFK:Mg2+ phosphorylates RIB (Schizosaccharomyces pombe)
2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)
2xENPP1 hydrolyzes FAD to FMN (Dictyostelium discoideum)
RFK:Mg2+ phosphorylates RIB (Caenorhabditis elegans)
2xENPP1 hydrolyzes FAD to FMN (Caenorhabditis elegans)
2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)
2xENPP1 hydrolyzes FAD to FMN (Danio rerio)
RFK:Mg2+ phosphorylates RIB (Sus scrofa)
2xENPP1 hydrolyzes FAD to FMN (Sus scrofa)
RFK:Mg2+ phosphorylates RIB (Bos taurus)
2xENPP1 hydrolyzes FAD to FMN (Bos taurus)
RFK:Mg2+ phosphorylates RIB (Canis familiaris)
2xENPP1 hydrolyzes FAD to FMN (Canis familiaris)
RFK:Mg2+ phosphorylates RIB (Rattus norvegicus)
2xENPP1 hydrolyzes FAD to FMN (Rattus norvegicus)
RFK:Mg2+ phosphorylates RIB (Mus musculus)
2xENPP1 hydrolyzes FAD to FMN (Mus musculus)
2xENPP1 hydrolyzes FAD to FMN (Homo sapiens)
RFK:Mg2+ phosphorylates RIB (Homo sapiens)
This entity regulates
Negatively
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Caenorhabditis elegans)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Drosophila melanogaster)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Gallus gallus)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Xenopus tropicalis)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Danio rerio)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Sus scrofa)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Bos taurus)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Canis familiaris)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Rattus norvegicus)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Homo sapiens)
SLC52A1,2,3 transport RIB from extracellular region to cytosol
(Mus musculus)
Other forms of this molecule
FMN [cytoplasm]
FMN [peroxisomal matrix]
FMN [mitochondrial inner membrane]
Cross References
COMPOUND
C00061
ZINC
000003831425
,
000011524518
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