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Na+ [extracellular region]
Stable Identifier
R-ALL-74113
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
sodium ion, sodium(1+), Sodium
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Digestion and absorption (Bos taurus)
Intestinal absorption (Bos taurus)
Intestinal hexose absorption (Bos taurus)
SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Ribavirin ADME (Bos taurus)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Hemostasis (Bos taurus)
Platelet homeostasis (Bos taurus)
Platelet calcium homeostasis (Bos taurus)
Elevation of cytosolic Ca2+ levels (Bos taurus)
Cation influx mediated by TRPC3/6/7 (Bos taurus)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Bos taurus)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Na+ [extracellular region]
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Antimicrobial peptides (Bos taurus)
Metal sequestration by antimicrobial proteins (Bos taurus)
S100A8:S100A9 binds Mn2+ (Bos taurus)
Na+ [extracellular region]
S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] (Bos taurus)
Na+ [extracellular region]
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Creatine metabolism (Bos taurus)
Creatine transport across the plasma membrane (Bos taurus)
Na+ [extracellular region]
Metabolism of amine-derived hormones (Bos taurus)
Thyroxine biosynthesis (Bos taurus)
Iodide is taken up by thyroid epithelial cells (Bos taurus)
Na+ [extracellular region]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Carnitine shuttle (Bos taurus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Bos taurus)
Na+ [extracellular region]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Recycling of bile acids and salts (Bos taurus)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Phospholipid metabolism (Bos taurus)
Glycerophospholipid biosynthesis (Bos taurus)
Synthesis of PC (Bos taurus)
MFSD2A transports LPC from extracellular region to plasma membrane (Bos taurus)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Biotin transport and metabolism (Bos taurus)
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Bos taurus)
Na+ [extracellular region]
Nicotinate metabolism (Bos taurus)
Nicotinamide salvaging (Bos taurus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Vitamin B5 (pantothenate) metabolism (Bos taurus)
SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Bos taurus)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Bos taurus)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Metabolism of proteins (Bos taurus)
Surfactant metabolism (Bos taurus)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Muscle contraction (Bos taurus)
Cardiac conduction (Bos taurus)
Ion homeostasis (Bos taurus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Na+ [extracellular region]
Phase 0 - rapid depolarisation (Bos taurus)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Neuronal System (Bos taurus)
Transmission across Chemical Synapses (Bos taurus)
Neurotransmitter clearance (Bos taurus)
Dopamine clearance from the synaptic cleft (Bos taurus)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Bos taurus)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Bos taurus)
Acetylcholine binding and downstream events (Bos taurus)
Postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Bos taurus)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Bos taurus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Bos taurus)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Bos taurus)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Bos taurus)
Unblocking of NMDA receptors, glutamate binding and activation (Bos taurus)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Bos taurus)
Na+ [extracellular region]
Activation of kainate receptors upon glutamate binding (Bos taurus)
Ionotropic activity of kainate receptors (Bos taurus)
Activation of Na-permeable kainate receptors (Bos taurus)
Activation of Edited Kainate receptors (Bos taurus)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Bos taurus)
Activation of AMPA receptors (Bos taurus)
Activation of Ca impermeable AMPA receptors (Bos taurus)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Bos taurus)
Na+ [extracellular region]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Bos taurus)
Na+ [extracellular region]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Bos taurus)
Na+ [extracellular region]
Neurotransmitter release cycle (Bos taurus)
Acetylcholine Neurotransmitter Release Cycle (Bos taurus)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Bos taurus)
Reuptake of GABA (Bos taurus)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Bos taurus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Bos taurus)
L-Glutamine transport into neurons (Bos taurus)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Bos taurus)
Na+ [extracellular region]
Sensory Perception (Bos taurus)
Sensory perception of taste (Bos taurus)
Sensory perception of salty taste (Bos taurus)
SCNN channels transport extracellular Na+ to cytosol (Bos taurus)
Na+ [extracellular region]
Visual phototransduction (Bos taurus)
The phototransduction cascade (Bos taurus)
Activation of the phototransduction cascade (Bos taurus)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Bos taurus)
Na+ [extracellular region]
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Ion transport by P-type ATPases (Bos taurus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Bos taurus)
Na+ [extracellular region]
Stimuli-sensing channels (Bos taurus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Bos taurus)
Na+ [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Bos taurus)
Na+ [extracellular region]
SLC9B1/C2 exchange Na+ for H+ (Bos taurus)
Na+ [extracellular region]
TRP channels (Bos taurus)
TRPM4,5 transport extracellular Na+ to cytosol (Bos taurus)
Na+ [extracellular region]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Bos taurus)
Cellular hexose transport (Bos taurus)
Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Bos taurus)
Na+ [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Bos taurus)
Inositol transporters (Bos taurus)
Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Bos taurus)
Na+ [extracellular region]
Na+/Cl- dependent neurotransmitter transporters (Bos taurus)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Bos taurus)
Na+ [extracellular region]
PROT mediates L-proline uptake (Bos taurus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Bos taurus)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Bos taurus)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Bos taurus)
Organic cation transport (Bos taurus)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SOAT can transport taurolithocholate-3-sulphate (Bos taurus)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Bos taurus)
NACT co-transports trivalent citrate and a sodium ion (Bos taurus)
Na+ [extracellular region]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Bos taurus)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Bos taurus)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Bos taurus)
Na+ [extracellular region]
NaS2 co-transports sulphate and two sodium ions (Bos taurus)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Bos taurus)
Amino acid transport across the plasma membrane (Bos taurus)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Bos taurus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Bos taurus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Bos taurus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Bos taurus)
Na+ [extracellular region]
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Bos taurus)
Na+ [extracellular region]
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Bos taurus)
Na+ [extracellular region]
SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Bos taurus)
Na+ [extracellular region]
SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Bos taurus)
Na+ [extracellular region]
SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Bos taurus)
Na+ [extracellular region]
SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Bos taurus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Bos taurus)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Bos taurus)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Bos taurus)
Na+ [extracellular region]
SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Bos taurus)
Na+ [extracellular region]
SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Bos taurus)
Na+ [extracellular region]
Bicarbonate transporters (Bos taurus)
Na+-driven Cl-/HCO3- exchanger transport (Bos taurus)
Na+ [extracellular region]
SLC4A4 cotransports Na+ with 3HCO3- (Bos taurus)
Na+ [extracellular region]
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Bos taurus)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Bos taurus)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Multifunctional anion exchangers (Bos taurus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Organic anion transporters (Bos taurus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Type I Na+-coupled phosphate co-transport (Bos taurus)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Bos taurus)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Type II Na+/Pi cotransporters (Bos taurus)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
SLC34A3 cotransports Pi, 2Na+ (Bos taurus)
Na+ [extracellular region]
Sodium/Calcium exchangers (Bos taurus)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Bos taurus)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Bos taurus)
Na+ [extracellular region]
Sodium/Proton exchangers (Bos taurus)
Na+/H+ exchanger transport (at cell membrane) (Bos taurus)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
SLC5A6 transports vitamins from extracellular region to cytosol (Bos taurus)
Na+ [extracellular region]
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Bos taurus)
Na+ [extracellular region]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Bos taurus)
Na+ [extracellular region]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Bos taurus)
Na+ [extracellular region]
Drug ADME (Caenorhabditis elegans)
Azathioprine ADME (Caenorhabditis elegans)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Ribavirin ADME (Caenorhabditis elegans)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Hemostasis (Caenorhabditis elegans)
Platelet homeostasis (Caenorhabditis elegans)
Platelet calcium homeostasis (Caenorhabditis elegans)
Elevation of cytosolic Ca2+ levels (Caenorhabditis elegans)
Cation influx mediated by TRPC3/6/7 (Caenorhabditis elegans)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Caenorhabditis elegans)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Na+ [extracellular region]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Metabolism of amine-derived hormones (Caenorhabditis elegans)
Thyroxine biosynthesis (Caenorhabditis elegans)
Iodide is taken up by thyroid epithelial cells (Caenorhabditis elegans)
Na+ [extracellular region]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Carnitine shuttle (Caenorhabditis elegans)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Metabolism of steroids (Caenorhabditis elegans)
Bile acid and bile salt metabolism (Caenorhabditis elegans)
Recycling of bile acids and salts (Caenorhabditis elegans)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Nicotinate metabolism (Caenorhabditis elegans)
Nicotinamide salvaging (Caenorhabditis elegans)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Caenorhabditis elegans)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Metabolism of proteins (Caenorhabditis elegans)
Surfactant metabolism (Caenorhabditis elegans)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Muscle contraction (Caenorhabditis elegans)
Cardiac conduction (Caenorhabditis elegans)
Ion homeostasis (Caenorhabditis elegans)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Na+ [extracellular region]
Neuronal System (Caenorhabditis elegans)
Transmission across Chemical Synapses (Caenorhabditis elegans)
Neurotransmitter clearance (Caenorhabditis elegans)
Dopamine clearance from the synaptic cleft (Caenorhabditis elegans)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Caenorhabditis elegans)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Caenorhabditis elegans)
Acetylcholine binding and downstream events (Caenorhabditis elegans)
Postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Caenorhabditis elegans)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Caenorhabditis elegans)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Caenorhabditis elegans)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Caenorhabditis elegans)
Unblocking of NMDA receptors, glutamate binding and activation (Caenorhabditis elegans)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Caenorhabditis elegans)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Caenorhabditis elegans)
Activation of AMPA receptors (Caenorhabditis elegans)
Activation of Ca impermeable AMPA receptors (Caenorhabditis elegans)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Caenorhabditis elegans)
Na+ [extracellular region]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Caenorhabditis elegans)
Na+ [extracellular region]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Caenorhabditis elegans)
Na+ [extracellular region]
Neurotransmitter release cycle (Caenorhabditis elegans)
Acetylcholine Neurotransmitter Release Cycle (Caenorhabditis elegans)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Caenorhabditis elegans)
Reuptake of GABA (Caenorhabditis elegans)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Caenorhabditis elegans)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Caenorhabditis elegans)
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Caenorhabditis elegans)
Na+ [extracellular region]
Sensory Perception (Caenorhabditis elegans)
Sensory perception of taste (Caenorhabditis elegans)
Sensory perception of salty taste (Caenorhabditis elegans)
SCNN channels transport extracellular Na+ to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Visual phototransduction (Caenorhabditis elegans)
The phototransduction cascade (Caenorhabditis elegans)
Activation of the phototransduction cascade (Caenorhabditis elegans)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Caenorhabditis elegans)
Na+ [extracellular region]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Stimuli-sensing channels (Caenorhabditis elegans)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC9B1/C2 exchange Na+ for H+ (Caenorhabditis elegans)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of bile salts and organic acids, metal ions and amine compounds (Caenorhabditis elegans)
Na+/Cl- dependent neurotransmitter transporters (Caenorhabditis elegans)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Caenorhabditis elegans)
Na+ [extracellular region]
PROT mediates L-proline uptake (Caenorhabditis elegans)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Caenorhabditis elegans)
Organic cation transport (Caenorhabditis elegans)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SOAT can transport taurolithocholate-3-sulphate (Caenorhabditis elegans)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Caenorhabditis elegans)
NACT co-transports trivalent citrate and a sodium ion (Caenorhabditis elegans)
Na+ [extracellular region]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Caenorhabditis elegans)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Caenorhabditis elegans)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Caenorhabditis elegans)
Na+ [extracellular region]
NaS2 co-transports sulphate and two sodium ions (Caenorhabditis elegans)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Caenorhabditis elegans)
Amino acid transport across the plasma membrane (Caenorhabditis elegans)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Caenorhabditis elegans)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Bicarbonate transporters (Caenorhabditis elegans)
Na+-driven Cl-/HCO3- exchanger transport (Caenorhabditis elegans)
Na+ [extracellular region]
SLC4A4 cotransports Na+ with 3HCO3- (Caenorhabditis elegans)
Na+ [extracellular region]
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Caenorhabditis elegans)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Caenorhabditis elegans)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Multifunctional anion exchangers (Caenorhabditis elegans)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Organic anion transporters (Caenorhabditis elegans)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Type I Na+-coupled phosphate co-transport (Caenorhabditis elegans)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Caenorhabditis elegans)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
Type II Na+/Pi cotransporters (Caenorhabditis elegans)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Caenorhabditis elegans)
Na+ [extracellular region]
SLC34A3 cotransports Pi, 2Na+ (Caenorhabditis elegans)
Na+ [extracellular region]
Sodium/Calcium exchangers (Caenorhabditis elegans)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Caenorhabditis elegans)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Caenorhabditis elegans)
Na+ [extracellular region]
Sodium/Proton exchangers (Caenorhabditis elegans)
Na+/H+ exchanger transport (at cell membrane) (Caenorhabditis elegans)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Caenorhabditis elegans)
Na+ [extracellular region]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Caenorhabditis elegans)
Na+ [extracellular region]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Caenorhabditis elegans)
Na+ [extracellular region]
Digestion and absorption (Canis familiaris)
Intestinal absorption (Canis familiaris)
Intestinal hexose absorption (Canis familiaris)
SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Drug ADME (Canis familiaris)
Azathioprine ADME (Canis familiaris)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Ribavirin ADME (Canis familiaris)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Hemostasis (Canis familiaris)
Platelet homeostasis (Canis familiaris)
Platelet calcium homeostasis (Canis familiaris)
Elevation of cytosolic Ca2+ levels (Canis familiaris)
Cation influx mediated by TRPC3/6/7 (Canis familiaris)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Canis familiaris)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Na+ [extracellular region]
Immune System (Canis familiaris)
Innate Immune System (Canis familiaris)
Antimicrobial peptides (Canis familiaris)
Metal sequestration by antimicrobial proteins (Canis familiaris)
S100A8:S100A9 binds Mn2+ (Canis familiaris)
Na+ [extracellular region]
S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] (Canis familiaris)
Na+ [extracellular region]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Creatine metabolism (Canis familiaris)
Creatine transport across the plasma membrane (Canis familiaris)
Na+ [extracellular region]
Metabolism of amine-derived hormones (Canis familiaris)
Thyroxine biosynthesis (Canis familiaris)
Iodide is taken up by thyroid epithelial cells (Canis familiaris)
Na+ [extracellular region]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Carnitine shuttle (Canis familiaris)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Canis familiaris)
Na+ [extracellular region]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Phospholipid metabolism (Canis familiaris)
Glycerophospholipid biosynthesis (Canis familiaris)
Synthesis of PC (Canis familiaris)
MFSD2A transports LPC from extracellular region to plasma membrane (Canis familiaris)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Biotin transport and metabolism (Canis familiaris)
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Canis familiaris)
Na+ [extracellular region]
Nicotinate metabolism (Canis familiaris)
Nicotinamide salvaging (Canis familiaris)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Vitamin B5 (pantothenate) metabolism (Canis familiaris)
SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Canis familiaris)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Canis familiaris)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Metabolism of proteins (Canis familiaris)
Surfactant metabolism (Canis familiaris)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Muscle contraction (Canis familiaris)
Cardiac conduction (Canis familiaris)
Ion homeostasis (Canis familiaris)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Canis familiaris)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Na+ [extracellular region]
Neuronal System (Canis familiaris)
Transmission across Chemical Synapses (Canis familiaris)
Neurotransmitter clearance (Canis familiaris)
Dopamine clearance from the synaptic cleft (Canis familiaris)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Canis familiaris)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Canis familiaris)
Acetylcholine binding and downstream events (Canis familiaris)
Postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Canis familiaris)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Canis familiaris)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Canis familiaris)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Canis familiaris)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Canis familiaris)
Unblocking of NMDA receptors, glutamate binding and activation (Canis familiaris)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Canis familiaris)
Na+ [extracellular region]
Activation of kainate receptors upon glutamate binding (Canis familiaris)
Ionotropic activity of kainate receptors (Canis familiaris)
Activation of Na-permeable kainate receptors (Canis familiaris)
Activation of Edited Kainate receptors (Canis familiaris)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Canis familiaris)
Activation of AMPA receptors (Canis familiaris)
Activation of Ca impermeable AMPA receptors (Canis familiaris)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Canis familiaris)
Na+ [extracellular region]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Canis familiaris)
Na+ [extracellular region]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Canis familiaris)
Na+ [extracellular region]
Neurotransmitter release cycle (Canis familiaris)
Acetylcholine Neurotransmitter Release Cycle (Canis familiaris)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Canis familiaris)
Reuptake of GABA (Canis familiaris)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Canis familiaris)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Canis familiaris)
L-Glutamine transport into neurons (Canis familiaris)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Canis familiaris)
Na+ [extracellular region]
Sensory Perception (Canis familiaris)
Sensory perception of taste (Canis familiaris)
Sensory perception of salty taste (Canis familiaris)
SCNN channels transport extracellular Na+ to cytosol (Canis familiaris)
Na+ [extracellular region]
Visual phototransduction (Canis familiaris)
The phototransduction cascade (Canis familiaris)
Activation of the phototransduction cascade (Canis familiaris)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Canis familiaris)
Na+ [extracellular region]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Ion transport by P-type ATPases (Canis familiaris)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Canis familiaris)
Na+ [extracellular region]
Stimuli-sensing channels (Canis familiaris)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Canis familiaris)
Na+ [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC9B1/C2 exchange Na+ for H+ (Canis familiaris)
Na+ [extracellular region]
TRP channels (Canis familiaris)
TRPM4,5 transport extracellular Na+ to cytosol (Canis familiaris)
Na+ [extracellular region]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Canis familiaris)
Cellular hexose transport (Canis familiaris)
Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Canis familiaris)
Na+ [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Canis familiaris)
Inositol transporters (Canis familiaris)
Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Canis familiaris)
Na+ [extracellular region]
SLC5A3 (SMIT1) transports myo-inositol (Ins) with Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Na+/Cl- dependent neurotransmitter transporters (Canis familiaris)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Canis familiaris)
Na+ [extracellular region]
PROT mediates L-proline uptake (Canis familiaris)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Canis familiaris)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Canis familiaris)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Canis familiaris)
Organic cation transport (Canis familiaris)
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SOAT can transport taurolithocholate-3-sulphate (Canis familiaris)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Canis familiaris)
NACT co-transports trivalent citrate and a sodium ion (Canis familiaris)
Na+ [extracellular region]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Canis familiaris)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Canis familiaris)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Canis familiaris)
Na+ [extracellular region]
NaS2 co-transports sulphate and two sodium ions (Canis familiaris)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Canis familiaris)
Amino acid transport across the plasma membrane (Canis familiaris)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Canis familiaris)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Canis familiaris)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Canis familiaris)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Canis familiaris)
Na+ [extracellular region]
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Canis familiaris)
Na+ [extracellular region]
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Canis familiaris)
Na+ [extracellular region]
SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Canis familiaris)
Na+ [extracellular region]
SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Canis familiaris)
Na+ [extracellular region]
SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Canis familiaris)
Na+ [extracellular region]
SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Canis familiaris)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Canis familiaris)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Canis familiaris)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Canis familiaris)
Na+ [extracellular region]
SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Canis familiaris)
Na+ [extracellular region]
Bicarbonate transporters (Canis familiaris)
Na+-driven Cl-/HCO3- exchanger transport (Canis familiaris)
Na+ [extracellular region]
SLC4A4 cotransports Na+ with 3HCO3- (Canis familiaris)
Na+ [extracellular region]
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Canis familiaris)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Canis familiaris)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Multifunctional anion exchangers (Canis familiaris)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Organic anion transporters (Canis familiaris)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Type I Na+-coupled phosphate co-transport (Canis familiaris)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Canis familiaris)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Type II Na+/Pi cotransporters (Canis familiaris)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
SLC34A3 cotransports Pi, 2Na+ (Canis familiaris)
Na+ [extracellular region]
Sodium/Calcium exchangers (Canis familiaris)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Canis familiaris)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Canis familiaris)
Na+ [extracellular region]
Sodium/Proton exchangers (Canis familiaris)
Na+/H+ exchanger transport (at cell membrane) (Canis familiaris)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
SLC5A6 transports vitamins from extracellular region to cytosol (Canis familiaris)
Na+ [extracellular region]
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Canis familiaris)
Na+ [extracellular region]
Digestion and absorption (Danio rerio)
Intestinal absorption (Danio rerio)
Intestinal hexose absorption (Danio rerio)
SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Hemostasis (Danio rerio)
Platelet homeostasis (Danio rerio)
Platelet calcium homeostasis (Danio rerio)
Elevation of cytosolic Ca2+ levels (Danio rerio)
Cation influx mediated by TRPC3/6/7 (Danio rerio)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Danio rerio)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Na+ [extracellular region]
Immune System (Danio rerio)
Innate Immune System (Danio rerio)
Antimicrobial peptides (Danio rerio)
Metal sequestration by antimicrobial proteins (Danio rerio)
S100A8:S100A9 binds Mn2+ (Danio rerio)
Na+ [extracellular region]
S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] (Danio rerio)
Na+ [extracellular region]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Metabolism of amine-derived hormones (Danio rerio)
Thyroxine biosynthesis (Danio rerio)
Iodide is taken up by thyroid epithelial cells (Danio rerio)
Na+ [extracellular region]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Carnitine shuttle (Danio rerio)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Danio rerio)
Na+ [extracellular region]
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Recycling of bile acids and salts (Danio rerio)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Phospholipid metabolism (Danio rerio)
Glycerophospholipid biosynthesis (Danio rerio)
Synthesis of PC (Danio rerio)
MFSD2A transports LPC from extracellular region to plasma membrane (Danio rerio)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Biotin transport and metabolism (Danio rerio)
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Danio rerio)
Na+ [extracellular region]
Nicotinate metabolism (Danio rerio)
Nicotinamide salvaging (Danio rerio)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Vitamin B5 (pantothenate) metabolism (Danio rerio)
SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Danio rerio)
Na+ [extracellular region]
Metabolism of proteins (Danio rerio)
Surfactant metabolism (Danio rerio)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Muscle contraction (Danio rerio)
Cardiac conduction (Danio rerio)
Ion homeostasis (Danio rerio)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Danio rerio)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Na+ [extracellular region]
Neuronal System (Danio rerio)
Transmission across Chemical Synapses (Danio rerio)
Neurotransmitter clearance (Danio rerio)
Dopamine clearance from the synaptic cleft (Danio rerio)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Danio rerio)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Danio rerio)
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Danio rerio)
Activation of AMPA receptors (Danio rerio)
Activation of Ca permeable AMPA receptors (Danio rerio)
Na+ [extracellular region]
Neurotransmitter release cycle (Danio rerio)
GABA synthesis, release, reuptake and degradation (Danio rerio)
Reuptake of GABA (Danio rerio)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Danio rerio)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Danio rerio)
L-Glutamine transport into neurons (Danio rerio)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Danio rerio)
Na+ [extracellular region]
Transport of small molecules (Danio rerio)
Ion channel transport (Danio rerio)
Ion transport by P-type ATPases (Danio rerio)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Danio rerio)
Na+ [extracellular region]
Stimuli-sensing channels (Danio rerio)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Danio rerio)
Na+ [extracellular region]
TRP channels (Danio rerio)
TRPM4,5 transport extracellular Na+ to cytosol (Danio rerio)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Danio rerio)
Cellular hexose transport (Danio rerio)
Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Danio rerio)
Na+ [extracellular region]
SLC5A2 cotransports Na+ and glucose from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC5As, NAGLT1 cotransport Glc and Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Danio rerio)
Inositol transporters (Danio rerio)
Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Danio rerio)
Na+ [extracellular region]
Na+/Cl- dependent neurotransmitter transporters (Danio rerio)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Danio rerio)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Danio rerio)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Danio rerio)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Danio rerio)
Organic cation transport (Danio rerio)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Danio rerio)
NaDC1 co-transports dicarboxylic acids and a sodium ion (Danio rerio)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Danio rerio)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Danio rerio)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Danio rerio)
Amino acid transport across the plasma membrane (Danio rerio)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Danio rerio)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Danio rerio)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Danio rerio)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Danio rerio)
Na+ [extracellular region]
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Danio rerio)
Na+ [extracellular region]
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Danio rerio)
Na+ [extracellular region]
SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Danio rerio)
Na+ [extracellular region]
SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Danio rerio)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Danio rerio)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Danio rerio)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Danio rerio)
Na+ [extracellular region]
SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Danio rerio)
Na+ [extracellular region]
SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Danio rerio)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Danio rerio)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Multifunctional anion exchangers (Danio rerio)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Organic anion transporters (Danio rerio)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Danio rerio)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Type II Na+/Pi cotransporters (Danio rerio)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Sodium/Calcium exchangers (Danio rerio)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Danio rerio)
Na+ [extracellular region]
Sodium/Proton exchangers (Danio rerio)
Na+/H+ exchanger transport (at cell membrane) (Danio rerio)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Danio rerio)
SLC5A6 transports vitamins from extracellular region to cytosol (Danio rerio)
Na+ [extracellular region]
Metabolism (Dictyostelium discoideum)
Metabolism of lipids (Dictyostelium discoideum)
Phospholipid metabolism (Dictyostelium discoideum)
Glycerophospholipid biosynthesis (Dictyostelium discoideum)
Synthesis of PC (Dictyostelium discoideum)
MFSD2A transports LPC from extracellular region to plasma membrane (Dictyostelium discoideum)
Na+ [extracellular region]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of inorganic cations/anions and amino acids/oligopeptides (Dictyostelium discoideum)
Organic anion transporters (Dictyostelium discoideum)
Type I Na+-coupled phosphate co-transport (Dictyostelium discoideum)
Na+ [extracellular region]
Sodium/Proton exchangers (Dictyostelium discoideum)
Na+/H+ exchanger transport (at cell membrane) (Dictyostelium discoideum)
Na+ [extracellular region]
Drug ADME (Drosophila melanogaster)
Azathioprine ADME (Drosophila melanogaster)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Ribavirin ADME (Drosophila melanogaster)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Hemostasis (Drosophila melanogaster)
Platelet homeostasis (Drosophila melanogaster)
Platelet calcium homeostasis (Drosophila melanogaster)
Reduction of cytosolic Ca++ levels (Drosophila melanogaster)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Na+ [extracellular region]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Metabolism of amine-derived hormones (Drosophila melanogaster)
Thyroxine biosynthesis (Drosophila melanogaster)
Iodide is taken up by thyroid epithelial cells (Drosophila melanogaster)
Na+ [extracellular region]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Carnitine shuttle (Drosophila melanogaster)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Recycling of bile acids and salts (Drosophila melanogaster)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Nicotinate metabolism (Drosophila melanogaster)
Nicotinamide salvaging (Drosophila melanogaster)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Drosophila melanogaster)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Muscle contraction (Drosophila melanogaster)
Cardiac conduction (Drosophila melanogaster)
Ion homeostasis (Drosophila melanogaster)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Na+ [extracellular region]
Neuronal System (Drosophila melanogaster)
Transmission across Chemical Synapses (Drosophila melanogaster)
Neurotransmitter clearance (Drosophila melanogaster)
Dopamine clearance from the synaptic cleft (Drosophila melanogaster)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Drosophila melanogaster)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Drosophila melanogaster)
Acetylcholine binding and downstream events (Drosophila melanogaster)
Postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Drosophila melanogaster)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Drosophila melanogaster)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Drosophila melanogaster)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Drosophila melanogaster)
Unblocking of NMDA receptors, glutamate binding and activation (Drosophila melanogaster)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Drosophila melanogaster)
Na+ [extracellular region]
Activation of kainate receptors upon glutamate binding (Drosophila melanogaster)
Ionotropic activity of kainate receptors (Drosophila melanogaster)
Activation of Na-permeable kainate receptors (Drosophila melanogaster)
Activation of Edited Kainate receptors (Drosophila melanogaster)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Drosophila melanogaster)
Activation of AMPA receptors (Drosophila melanogaster)
Activation of Ca impermeable AMPA receptors (Drosophila melanogaster)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Drosophila melanogaster)
Na+ [extracellular region]
Neurotransmitter release cycle (Drosophila melanogaster)
Acetylcholine Neurotransmitter Release Cycle (Drosophila melanogaster)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Drosophila melanogaster)
Reuptake of GABA (Drosophila melanogaster)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Drosophila melanogaster)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Drosophila melanogaster)
L-Glutamine transport into neurons (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Drosophila melanogaster)
Na+ [extracellular region]
Sensory Perception (Drosophila melanogaster)
Visual phototransduction (Drosophila melanogaster)
The phototransduction cascade (Drosophila melanogaster)
Activation of the phototransduction cascade (Drosophila melanogaster)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Drosophila melanogaster)
Na+ [extracellular region]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Stimuli-sensing channels (Drosophila melanogaster)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC9B1/C2 exchange Na+ for H+ (Drosophila melanogaster)
Na+ [extracellular region]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of bile salts and organic acids, metal ions and amine compounds (Drosophila melanogaster)
Na+/Cl- dependent neurotransmitter transporters (Drosophila melanogaster)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Drosophila melanogaster)
Na+ [extracellular region]
PROT mediates L-proline uptake (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Drosophila melanogaster)
Organic cation transport (Drosophila melanogaster)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SOAT can transport taurolithocholate-3-sulphate (Drosophila melanogaster)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Drosophila melanogaster)
NACT co-transports trivalent citrate and a sodium ion (Drosophila melanogaster)
Na+ [extracellular region]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Drosophila melanogaster)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Drosophila melanogaster)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Drosophila melanogaster)
Na+ [extracellular region]
NaS2 co-transports sulphate and two sodium ions (Drosophila melanogaster)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Drosophila melanogaster)
Amino acid transport across the plasma membrane (Drosophila melanogaster)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A5-mediated exchange of alanine and glutamine across the plasma membrane (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A5-mediated exchange of glutamine and alanine across the plasma membrane (Drosophila melanogaster)
Na+ [extracellular region]
SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Drosophila melanogaster)
Na+ [extracellular region]
SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Drosophila melanogaster)
Na+ [extracellular region]
SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Drosophila melanogaster)
Na+ [extracellular region]
SLC38A5-mediated uptake of glutamine, histidine, asparagine, and serine (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC7A6 (y+LAT2)-mediated exchange of extracellular leucine for cytosolic arginine (Drosophila melanogaster)
Na+ [extracellular region]
SLC7A7:SLC3A2 exchanges L-Arg for L-Leu, Na+ across the plasma membrane (Drosophila melanogaster)
Na+ [extracellular region]
Bicarbonate transporters (Drosophila melanogaster)
Na+-driven Cl-/HCO3- exchanger transport (Drosophila melanogaster)
Na+ [extracellular region]
SLC4A4 cotransports Na+ with 3HCO3- (Drosophila melanogaster)
Na+ [extracellular region]
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Drosophila melanogaster)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Drosophila melanogaster)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC12A3 cotransports Cl-, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Multifunctional anion exchangers (Drosophila melanogaster)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Organic anion transporters (Drosophila melanogaster)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Type I Na+-coupled phosphate co-transport (Drosophila melanogaster)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Drosophila melanogaster)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Drosophila melanogaster)
Na+ [extracellular region]
Sodium/Calcium exchangers (Drosophila melanogaster)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Drosophila melanogaster)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Drosophila melanogaster)
Na+ [extracellular region]
Sodium/Proton exchangers (Drosophila melanogaster)
Na+/H+ exchanger transport (at cell membrane) (Drosophila melanogaster)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Concentrative transport (import) of a nucleoside and a sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 1 (Drosophila melanogaster)
Na+ [extracellular region]
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Drosophila melanogaster)
Na+ [extracellular region]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Drosophila melanogaster)
Na+ [extracellular region]
Digestion and absorption (Gallus gallus)
Intestinal absorption (Gallus gallus)
Intestinal hexose absorption (Gallus gallus)
SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Drug ADME (Gallus gallus)
Azathioprine ADME (Gallus gallus)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Ribavirin ADME (Gallus gallus)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Hemostasis (Gallus gallus)
Platelet homeostasis (Gallus gallus)
Platelet calcium homeostasis (Gallus gallus)
Elevation of cytosolic Ca2+ levels (Gallus gallus)
Cation influx mediated by TRPC3/6/7 (Gallus gallus)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Gallus gallus)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Na+ [extracellular region]
Immune System (Gallus gallus)
Innate Immune System (Gallus gallus)
Antimicrobial peptides (Gallus gallus)
Metal sequestration by antimicrobial proteins (Gallus gallus)
S100A8:S100A9 binds Mn2+ (Gallus gallus)
Na+ [extracellular region]
S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] (Gallus gallus)
Na+ [extracellular region]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Metabolism of amine-derived hormones (Gallus gallus)
Thyroxine biosynthesis (Gallus gallus)
Iodide is taken up by thyroid epithelial cells (Gallus gallus)
Na+ [extracellular region]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Carnitine shuttle (Gallus gallus)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Gallus gallus)
Na+ [extracellular region]
Metabolism of steroids (Gallus gallus)
Bile acid and bile salt metabolism (Gallus gallus)
Recycling of bile acids and salts (Gallus gallus)
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Phospholipid metabolism (Gallus gallus)
Glycerophospholipid biosynthesis (Gallus gallus)
Synthesis of PC (Gallus gallus)
MFSD2A transports LPC from extracellular region to plasma membrane (Gallus gallus)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Biotin transport and metabolism (Gallus gallus)
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Gallus gallus)
Na+ [extracellular region]
Nicotinate metabolism (Gallus gallus)
Nicotinamide salvaging (Gallus gallus)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Vitamin B5 (pantothenate) metabolism (Gallus gallus)
SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Gallus gallus)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Gallus gallus)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Metabolism of proteins (Gallus gallus)
Surfactant metabolism (Gallus gallus)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Muscle contraction (Gallus gallus)
Cardiac conduction (Gallus gallus)
Ion homeostasis (Gallus gallus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Na+ [extracellular region]
Neuronal System (Gallus gallus)
Transmission across Chemical Synapses (Gallus gallus)
Neurotransmitter clearance (Gallus gallus)
Serotonin clearance from the synaptic cleft (Gallus gallus)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Gallus gallus)
Acetylcholine binding and downstream events (Gallus gallus)
Postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Gallus gallus)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Gallus gallus)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Gallus gallus)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Gallus gallus)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Gallus gallus)
Unblocking of NMDA receptors, glutamate binding and activation (Gallus gallus)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Gallus gallus)
Na+ [extracellular region]
Activation of kainate receptors upon glutamate binding (Gallus gallus)
Ionotropic activity of kainate receptors (Gallus gallus)
Activation of Na-permeable kainate receptors (Gallus gallus)
Activation of Edited Kainate receptors (Gallus gallus)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Gallus gallus)
Activation of AMPA receptors (Gallus gallus)
Activation of Ca impermeable AMPA receptors (Gallus gallus)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Gallus gallus)
Na+ [extracellular region]
Neurotransmitter release cycle (Gallus gallus)
Acetylcholine Neurotransmitter Release Cycle (Gallus gallus)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Gallus gallus)
Reuptake of GABA (Gallus gallus)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Gallus gallus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Gallus gallus)
L-Glutamine transport into neurons (Gallus gallus)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Gallus gallus)
Na+ [extracellular region]
Sensory Perception (Gallus gallus)
Sensory perception of taste (Gallus gallus)
Sensory perception of salty taste (Gallus gallus)
SCNN channels transport extracellular Na+ to cytosol (Gallus gallus)
Na+ [extracellular region]
Visual phototransduction (Gallus gallus)
The phototransduction cascade (Gallus gallus)
Activation of the phototransduction cascade (Gallus gallus)
cGMP:CNG transports Na+ and Ca2+ into the rod outer segment (Gallus gallus)
Na+ [extracellular region]
Transport of small molecules (Gallus gallus)
Ion channel transport (Gallus gallus)
Ion transport by P-type ATPases (Gallus gallus)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Gallus gallus)
Na+ [extracellular region]
Stimuli-sensing channels (Gallus gallus)
ASIC trimers:H+ transport extracellular Na+ to cytosol (Gallus gallus)
Na+ [extracellular region]
SCNN channels transport extracellular Na+ to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC9B1/C2 exchange Na+ for H+ (Gallus gallus)
Na+ [extracellular region]
TRP channels (Gallus gallus)
TRPM4,5 transport extracellular Na+ to cytosol (Gallus gallus)
Na+ [extracellular region]
UNC79:UNC80:NALCN transports Na+ extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC-mediated transmembrane transport (Gallus gallus)
Cellular hexose transport (Gallus gallus)
Co-transport (influx) of glucose/mannose and Na+ ions by SGLT4 (Gallus gallus)
Na+ [extracellular region]
SLC5A10 cotransports Na+ with Man, Fru from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Transport of bile salts and organic acids, metal ions and amine compounds (Gallus gallus)
Inositol transporters (Gallus gallus)
Co-transport (influx) of myo-inositol/D-chiro-inositol and two Na+ ions by SGLT6 (Gallus gallus)
Na+ [extracellular region]
Na+/Cl- dependent neurotransmitter transporters (Gallus gallus)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Gallus gallus)
Na+ [extracellular region]
PROT mediates L-proline uptake (Gallus gallus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Gallus gallus)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A2 cotransports NAd, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A5,9 cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Gallus gallus)
Na+ [extracellular region]
Organic cation/anion/zwitterion transport (Gallus gallus)
Organic cation transport (Gallus gallus)
SLC22A4 cotransports ERGT, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC22A4, 5,15,16 cotransport CAR, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Sodium-coupled sulphate, di- and tri-carboxylate transporters (Gallus gallus)
NACT co-transports trivalent citrate and a sodium ion (Gallus gallus)
Na+ [extracellular region]
NaDC1 co-transports dicarboxylic acids and a sodium ion (Gallus gallus)
Na+ [extracellular region]
NaDC3 co-transports the dicarboxylic acid succinate and three sodium ion (Gallus gallus)
Na+ [extracellular region]
NaS1 co-transports sulphate and a sodium ion (Gallus gallus)
Na+ [extracellular region]
NaS2 co-transports sulphate and two sodium ions (Gallus gallus)
Na+ [extracellular region]
Transport of inorganic cations/anions and amino acids/oligopeptides (Gallus gallus)
Amino acid transport across the plasma membrane (Gallus gallus)
SLC1A4-mediated exchange of extracellular alanine for cytosolic serine, threonine, or cysteine (Gallus gallus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular cysteine for cytosolic alanine, serine, or threonine (Gallus gallus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular serine for cytosolic alanine, threonine, or cysteine (Gallus gallus)
Na+ [extracellular region]
SLC1A4-mediated exchange of extracellular threonine for cytosolic alanine, serine, or cysteine (Gallus gallus)
Na+ [extracellular region]
SLC38A1 (ATA1)-mediated uptake of neutral amino acids (Gallus gallus)
Na+ [extracellular region]
SLC38A2 (ATA2)-mediated uptake of neutral amino acids (Gallus gallus)
Na+ [extracellular region]
SLC38A3-mediated uptake of glutamine, histidine, asparagine, and alanine (Gallus gallus)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Gallus gallus)
Na+ [extracellular region]
SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A15-mediated amino acid uptake (Gallus gallus)
Na+ [extracellular region]
SLC6A19 cotransports neutral amino acids, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A20 cotransports L-Pro, Na+ from the extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC6A6-mediated uptake of taurine and beta-alanine (Gallus gallus)
Na+ [extracellular region]
Bicarbonate transporters (Gallus gallus)
Na+-driven Cl-/HCO3- exchanger transport (Gallus gallus)
Na+ [extracellular region]
SLC4A4 cotransports Na+ with 3HCO3- (Gallus gallus)
Na+ [extracellular region]
SLC4A5,7,9 cotransport Na+ with 3HCO3- (Gallus gallus)
Na+ [extracellular region]
Cation-coupled Chloride cotransporters (Gallus gallus)
SLC12A1,2 cotransports Na+, K+, 2Cl- from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Multifunctional anion exchangers (Gallus gallus)
SLC5A12 cotransports Na+ with LACT, PYR, NCA from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Organic anion transporters (Gallus gallus)
SLC5A5 cotransports Na+ with I- from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
SLC1A1,2,3,6,7 cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Sodium-coupled phosphate cotransporters (Gallus gallus)
SLC20A1,2 cotransport Pi, Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Type II Na+/Pi cotransporters (Gallus gallus)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Sodium/Calcium exchangers (Gallus gallus)
SLC24A1-4 exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Gallus gallus)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Gallus gallus)
Na+ [extracellular region]
Sodium/Proton exchangers (Gallus gallus)
Na+/H+ exchanger transport (at cell membrane) (Gallus gallus)
Na+ [extracellular region]
Transport of vitamins, nucleosides, and related molecules (Gallus gallus)
SLC5A6 transports vitamins from extracellular region to cytosol (Gallus gallus)
Na+ [extracellular region]
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Gallus gallus)
Concentrative transport (import) of a nucleoside and two sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 3 (Gallus gallus)
Na+ [extracellular region]
Concentrative transport (import) of nucleosides plus sodium ions by solute carrier family 28 (sodium-coupled nucleoside transporter), member 2 (Gallus gallus)
Na+ [extracellular region]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to mechanical stimuli (Homo sapiens)
Response of endothelial cells to shear stress (Homo sapiens)
High laminar flow shear stress activates signaling by PIEZO1 and PECAM1:CDH5:KDR in endothelial cells (Homo sapiens)
PIEZO1 trimer passively transports cations across the plasma membrane according to their electrochemical gradients (Homo sapiens)
Na+ [extracellular region]
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Homo sapiens)
PIEZO1 trimer passively transports cations across the plasma membrane according to their electrochemical gradients (Homo sapiens)
Na+ [extracellular region]
Digestion and absorption (Homo sapiens)
Intestinal absorption (Homo sapiens)
Intestinal hexose absorption (Homo sapiens)
SLC5A1 cotransports Glc,Gal with Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases associated with surfactant metabolism (Homo sapiens)
Defective SLC34A2 causes PALM (Homo sapiens)
Defective SLC34A2 does not cotransport HPO4(2-), 3Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Disorders of transmembrane transporters (Homo sapiens)
SLC transporter disorders (Homo sapiens)
Defective SLC12A1 causes Bartter syndrome 1 (BS1) (Homo sapiens)
Defective SLC12A1 does not cotransport Na+, K+, 2Cl- from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC12A3 causes Gitelman syndrome (GS) (Homo sapiens)
Defective SLC12A3 does not cotransport Cl-, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC1A1 is implicated in schizophrenia 18 (SCZD18) and dicarboxylic aminoaciduria (DCBXA) (Homo sapiens)
SLC1A1 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC1A3 causes episodic ataxia 6 (EA6) (Homo sapiens)
Defective SLC1A3 does not cotransport L-Glu,L-Asp,D-Asp,H+,3Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC20A2 causes idiopathic basal ganglia calcification 1 (IBGC1) (Homo sapiens)
Defective SLC20A2 does not cotransport Pi, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC22A5 causes systemic primary carnitine deficiency (CDSP) (Homo sapiens)
Defective SLC22A5 does not cotransport CAR, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC24A1 causes congenital stationary night blindness 1D (CSNB1D) (Homo sapiens)
Defective SLC24A1 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC24A4 causes hypomineralized amelogenesis imperfecta (AI) (Homo sapiens)
Defective SLC24A4 does not exchange extracellular 4Na+ for cytosolic Ca2+, K+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1) (Homo sapiens)
Defective SLC34A1 does not cotransport Pi, 3Na+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC34A2 causes pulmonary alveolar microlithiasis (PALM) (Homo sapiens)
Defective SLC34A2 does not cotransport Pi, 3Na+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC34A3 causes Hereditary hypophosphatemic rickets with hypercalciuria (HHRH) (Homo sapiens)
Defective SLC34A3 does not cotransport Pi, 2Na+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM) (Homo sapiens)
Defective SLC5A1 does not cotransport Glc and Na+ (Homo sapiens)
Na+ [extracellular region]
Defective SLC5A2 causes renal glucosuria (GLYS1) (Homo sapiens)
Defective SLC5A2 does not cotransport Glc and Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC5A5 causes thyroid dyshormonogenesis 1 (TDH1) (Homo sapiens)
Defective SLC5A5 does not cotransport Na+ with I- from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC5A7 causes distal hereditary motor neuronopathy 7A (HMN7A) (Homo sapiens)
Defective SLC5A7 does not cotransport Cho, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC6A19 causes Hartnup disorder (HND) (Homo sapiens)
Defective SLC6A19 does not cotransport neutral amino acids, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC6A2 causes orthostatic intolerance (OI) (Homo sapiens)
Defective SLC6A2 does not cotransport NAd, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC6A3 causes Parkinsonism-dystonia infantile (PKDYS) (Homo sapiens)
Defective SLC6A3 does not cotransport DA, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC6A5 causes hyperekplexia 3 (HKPX3) (Homo sapiens)
Defective SLC6A5 does not cotransport Gly, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Defective SLC7A7 causes lysinuric protein intolerance (LPI) (Homo sapiens)
Defective SLC7A7 does not exchange L-Arg for L-Leu, Na+ across the plasma membrane (Homo sapiens)
Na+ [extracellular region]
Variant SLC6A14 may confer susceptibility towards obesity (Homo sapiens)
Variant SLC6A14 cotransports SLC6A14 ligands, Cl-, 2Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Variant SLC6A20 contributes towards hyperglycinuria (HG) and iminoglycinuria (IG) (Homo sapiens)
Variant SLC6A20 does not cotransport L-Pro, Na+ from extracellulare region to cytosol (Homo sapiens)
Na+ [extracellular region]
Drug ADME (Homo sapiens)
Azathioprine ADME (Homo sapiens)
SLC28A2,3 cotransport 6MP and Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Ribavirin ADME (Homo sapiens)
SLC28C2,3 cotransports RBV, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Hemostasis (Homo sapiens)
Platelet homeostasis (Homo sapiens)
Platelet calcium homeostasis (Homo sapiens)
Elevation of cytosolic Ca2+ levels (Homo sapiens)
Cation influx mediated by TRPC3/6/7 (Homo sapiens)
Cations [extracellular region]
Na+ [extracellular region]
Reduction of cytosolic Ca++ levels (Homo sapiens)
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
Na+ [extracellular region]
Immune System (Homo sapiens)
Innate Immune System (Homo sapiens)
Antimicrobial peptides (Homo sapiens)
Metal sequestration by antimicrobial proteins (Homo sapiens)
S100A8:S100A9 binds Mn2+ (Homo sapiens)
Na+ [extracellular region]
S100A8:S100A9:Ca2+:Mn2+:Na+ [extracellular region] (Homo sapiens)
Na+ [extracellular region]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Creatine metabolism (Homo sapiens)
Creatine transport across the plasma membrane (Homo sapiens)
Na+ [extracellular region]
Metabolism of amine-derived hormones (Homo sapiens)
Thyroxine biosynthesis (Homo sapiens)
Iodide is taken up by thyroid epithelial cells (Homo sapiens)
Na+ [extracellular region]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Carnitine shuttle (Homo sapiens)
OCTN2 / SLC22A5 transports CAR from extracellular space to cytosol (Homo sapiens)
Na+ [extracellular region]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
SLC10A1 co-transport bile salts and Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
SLC10A2 transports bile salts and acids and Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Phospholipid metabolism (Homo sapiens)
Glycerophospholipid biosynthesis (Homo sapiens)
Synthesis of PC (Homo sapiens)
MFSD2A transports LPC from extracellular region to plasma membrane (Homo sapiens)
Na+ [extracellular region]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Biotin transport and metabolism (Homo sapiens)
SLC5A6 cotransports extracellular Btn and 2xNa+ to cytosol (Homo sapiens)
Na+ [extracellular region]
Nicotinate metabolism (Homo sapiens)
Nicotinamide salvaging (Homo sapiens)
SLC5A8 transports monocarboxylates from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Vitamin B5 (pantothenate) metabolism (Homo sapiens)
SLC5A6 cotransports extracellular PanK and 2Na+ to cytosol (Homo sapiens)
Na+ [extracellular region]
Vitamin C (ascorbate) metabolism (Homo sapiens)
SLC23A1,2 cotransports AscH-, 2Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Metabolism of proteins (Homo sapiens)
Surfactant metabolism (Homo sapiens)
SLC34A1,2 cotransports Pi, 3Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Muscle contraction (Homo sapiens)
Cardiac conduction (Homo sapiens)
Ion homeostasis (Homo sapiens)
ATP1A:ATP1B:FXYD exchanges 3Na+ for 2K+ (Homo sapiens)
Na+ [extracellular region]
SLC8A1,2,3 exchange 3Na+ for Ca2+ (Homo sapiens)
Na+ [extracellular region]
Phase 0 - rapid depolarisation (Homo sapiens)
SCNAs:SNCBs transport Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Neuronal System (Homo sapiens)
Transmission across Chemical Synapses (Homo sapiens)
Neurotransmitter clearance (Homo sapiens)
Dopamine clearance from the synaptic cleft (Homo sapiens)
SLC6A3 cotransports DA, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Serotonin clearance from the synaptic cleft (Homo sapiens)
SLC6A4 co-transports 5HT, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
Neurotransmitter receptors and postsynaptic signal transmission (Homo sapiens)
Acetylcholine binding and downstream events (Homo sapiens)
Postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Na+ [extracellular region]
Presynaptic nicotinic acetylcholine receptors (Homo sapiens)
Highly sodium permeable postsynaptic acetylcholine nicotinic receptors (Homo sapiens)
Activation of highly sodium permeable postsynaptic nicotinic acetylcholine receptors (Homo sapiens)
Na+ [extracellular region]
Activation of NMDA receptors and postsynaptic events (Homo sapiens)
Unblocking of NMDA receptors, glutamate binding and activation (Homo sapiens)
Membrane depolarization upon activation of Ca impermeable AMPA receptors (Homo sapiens)
Na+ [extracellular region]
Activation of kainate receptors upon glutamate binding (Homo sapiens)
Ionotropic activity of kainate receptors (Homo sapiens)
Activation of Na-permeable kainate receptors (Homo sapiens)
Activation of Edited Kainate receptors (Homo sapiens)
Na+ [extracellular region]
Glutamate binding, activation of AMPA receptors and synaptic plasticity (Homo sapiens)
Activation of AMPA receptors (Homo sapiens)
Activation of Ca impermeable AMPA receptors (Homo sapiens)
Na+ [extracellular region]
Activation of Ca permeable AMPA receptors (Homo sapiens)
Na+ [extracellular region]
HTR3 pentamers:5HT transport Na+,K+,Ca2+ (Homo sapiens)
Na+ [extracellular region]
HTR3A pentamer:5HT transports Na+,K+,Ca2+ (Homo sapiens)
Na+ [extracellular region]
Neurotransmitter release cycle (Homo sapiens)
Acetylcholine Neurotransmitter Release Cycle (Homo sapiens)
SLC5A7 cotransports Cho, Cl-, Na+ from extracellular region to cytosol (Homo sapiens)
Na+ [extracellular region]
GABA synthesis, release, reuptake and degradation (Homo sapiens)
Reuptake of GABA (Homo sapiens)
GAT1-3 mediate Na+/Cl- dependent GABA transport (Homo sapiens)
Na+ [extracellular region]
SLC6A12 (BGT-1)-mediated uptake of GABA and betaine (Homo sapiens)
Na+ [extracellular region]
Glutamate Neurotransmitter Release Cycle (Homo sapiens)
L-Glutamine transport into neurons (Homo sapiens)
Na+ [extracellular region]
SLC1A1-3,6,7 exchange L-Glu, H+ and 3Na+ for K+ (Homo sapiens)
Na+ [extracellular region]
Sensory Perception (Homo sapiens)
Olfactory Signaling Pathway (Homo sapiens)
cAMP:olfactory CNG channel translocates Na+ and Ca2+ from the extracellular region to the cytosol (Homo sapiens)
Na+ [extracellular region]
Sensory perception of taste (Homo sapiens)
Sensory perception of salty taste (Homo sapiens)
SCNN channels transport extracellular Na+ to cytosol (Homo sapiens)
Na+ [extracellular region]
Sensory perception of sweet, bitter, and umami (glutamate) taste (Homo sapiens)
SCN2A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
Na+ [extracellular region]
SCN3A:SCN2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
Na+ [extracellular region]
SCN9A:SCN1B,2B,4B transports Na+ from the extracellular region to the cytosol (Homo sapiens)
Na+ [extracellular region]