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What is Reactome ?
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How do I search ?
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H+ [endosome lumen]
Stable Identifier
R-ALL-74722
Type
Chemical Compound [SimpleEntity]
Compartment
endosome lumen
Synonyms
hydron
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by Insulin receptor (Bos taurus)
Insulin receptor recycling (Bos taurus)
Endosome acidification (Bos taurus)
H+ [endosome lumen]
Transport of small molecules (Bos taurus)
Ion channel transport (Bos taurus)
Stimuli-sensing channels (Bos taurus)
CLCN4/5/6 exchange Cl- for H+ (Bos taurus)
H+ [endosome lumen]
Iron uptake and transport (Bos taurus)
Transferrin endocytosis and recycling (Bos taurus)
Acidification of Tf:TfR1 containing endosome (Bos taurus)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Bos taurus)
H+ [endosome lumen]
Signal Transduction (Caenorhabditis elegans)
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by Insulin receptor (Caenorhabditis elegans)
Insulin receptor recycling (Caenorhabditis elegans)
Endosome acidification (Caenorhabditis elegans)
H+ [endosome lumen]
Transport of small molecules (Caenorhabditis elegans)
Ion channel transport (Caenorhabditis elegans)
Stimuli-sensing channels (Caenorhabditis elegans)
CLCN4/5/6 exchange Cl- for H+ (Caenorhabditis elegans)
H+ [endosome lumen]
Iron uptake and transport (Caenorhabditis elegans)
Transferrin endocytosis and recycling (Caenorhabditis elegans)
Acidification of Tf:TfR1 containing endosome (Caenorhabditis elegans)
H+ [endosome lumen]
Signal Transduction (Canis familiaris)
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor recycling (Canis familiaris)
Endosome acidification (Canis familiaris)
H+ [endosome lumen]
Transport of small molecules (Canis familiaris)
Ion channel transport (Canis familiaris)
Stimuli-sensing channels (Canis familiaris)
CLCN4/5/6 exchange Cl- for H+ (Canis familiaris)
H+ [endosome lumen]
Iron uptake and transport (Canis familiaris)
Transferrin endocytosis and recycling (Canis familiaris)
Acidification of Tf:TfR1 containing endosome (Canis familiaris)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Canis familiaris)
H+ [endosome lumen]
Signal Transduction (Danio rerio)
Signaling by Receptor Tyrosine Kinases (Danio rerio)
Signaling by Insulin receptor (Danio rerio)
Insulin receptor recycling (Danio rerio)
Endosome acidification (Danio rerio)
H+ [endosome lumen]
Transport of small molecules (Danio rerio)
Ion channel transport (Danio rerio)
Stimuli-sensing channels (Danio rerio)
CLCN4/5/6 exchange Cl- for H+ (Danio rerio)
H+ [endosome lumen]
Iron uptake and transport (Danio rerio)
Transferrin endocytosis and recycling (Danio rerio)
Acidification of Tf:TfR1 containing endosome (Danio rerio)
H+ [endosome lumen]
Signal Transduction (Dictyostelium discoideum)
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by Insulin receptor (Dictyostelium discoideum)
Insulin receptor recycling (Dictyostelium discoideum)
Endosome acidification (Dictyostelium discoideum)
H+ [endosome lumen]
Transport of small molecules (Dictyostelium discoideum)
Ion channel transport (Dictyostelium discoideum)
Stimuli-sensing channels (Dictyostelium discoideum)
CLCN4/5/6 exchange Cl- for H+ (Dictyostelium discoideum)
H+ [endosome lumen]
Iron uptake and transport (Dictyostelium discoideum)
Transferrin endocytosis and recycling (Dictyostelium discoideum)
Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)
H+ [endosome lumen]
Signal Transduction (Drosophila melanogaster)
Signaling by Receptor Tyrosine Kinases (Drosophila melanogaster)
Signaling by Insulin receptor (Drosophila melanogaster)
Insulin receptor recycling (Drosophila melanogaster)
Endosome acidification (Drosophila melanogaster)
H+ [endosome lumen]
Transport of small molecules (Drosophila melanogaster)
Ion channel transport (Drosophila melanogaster)
Stimuli-sensing channels (Drosophila melanogaster)
CLCN4/5/6 exchange Cl- for H+ (Drosophila melanogaster)
H+ [endosome lumen]
Iron uptake and transport (Drosophila melanogaster)
Transferrin endocytosis and recycling (Drosophila melanogaster)
Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)
H+ [endosome lumen]
Signal Transduction (Gallus gallus)
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by Insulin receptor (Gallus gallus)
Insulin receptor recycling (Gallus gallus)
Endosome acidification (Gallus gallus)
H+ [endosome lumen]
Transport of small molecules (Gallus gallus)
Ion channel transport (Gallus gallus)
Stimuli-sensing channels (Gallus gallus)
CLCN4/5/6 exchange Cl- for H+ (Gallus gallus)
H+ [endosome lumen]
Iron uptake and transport (Gallus gallus)
Transferrin endocytosis and recycling (Gallus gallus)
Acidification of Tf:TfR1 containing endosome (Gallus gallus)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Gallus gallus)
H+ [endosome lumen]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Bacterial Infection Pathways (Homo sapiens)
Uptake and actions of bacterial toxins (Homo sapiens)
Uptake and function of anthrax toxins (Homo sapiens)
pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
H+ [endosome lumen]
pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol) (Homo sapiens)
H+ [endosome lumen]
Viral Infection Pathways (Homo sapiens)
Influenza Infection (Homo sapiens)
Fusion and Uncoating of the Influenza Virion (Homo sapiens)
Uncoating of the Influenza Virion (Homo sapiens)
Ribonucleoprotein release from M1 proteins (Homo sapiens)
Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
H+ [endosome lumen]
Virion-associated M2 protein mediated ion infusion (Homo sapiens)
H+ [endosome lumen]
Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
H+ [endosome lumen]
Signal Transduction (Homo sapiens)
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor recycling (Homo sapiens)
Endosome acidification (Homo sapiens)
H+ [endosome lumen]
Transport of small molecules (Homo sapiens)
Ion channel transport (Homo sapiens)
Stimuli-sensing channels (Homo sapiens)
CLCN4/5/6 exchange Cl- for H+ (Homo sapiens)
H+ [endosome lumen]
Iron uptake and transport (Homo sapiens)
Transferrin endocytosis and recycling (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Homo sapiens)
H+ [endosome lumen]
Signal Transduction (Mus musculus)
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by Insulin receptor (Mus musculus)
Insulin receptor recycling (Mus musculus)
Endosome acidification (Mus musculus)
H+ [endosome lumen]
Transport of small molecules (Mus musculus)
Ion channel transport (Mus musculus)
Stimuli-sensing channels (Mus musculus)
CLCN4/5/6 exchange Cl- for H+ (Mus musculus)
H+ [endosome lumen]
Iron uptake and transport (Mus musculus)
Transferrin endocytosis and recycling (Mus musculus)
Acidification of Tf:TfR1 containing endosome (Mus musculus)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Mus musculus)
H+ [endosome lumen]
Signal Transduction (Plasmodium falciparum)
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by Insulin receptor (Plasmodium falciparum)
Insulin receptor recycling (Plasmodium falciparum)
Endosome acidification (Plasmodium falciparum)
H+ [endosome lumen]
Transport of small molecules (Plasmodium falciparum)
Iron uptake and transport (Plasmodium falciparum)
Transferrin endocytosis and recycling (Plasmodium falciparum)
Acidification of Tf:TfR1 containing endosome (Plasmodium falciparum)
H+ [endosome lumen]
Signal Transduction (Rattus norvegicus)
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by Insulin receptor (Rattus norvegicus)
Insulin receptor recycling (Rattus norvegicus)
Endosome acidification (Rattus norvegicus)
H+ [endosome lumen]
Transport of small molecules (Rattus norvegicus)
Ion channel transport (Rattus norvegicus)
Stimuli-sensing channels (Rattus norvegicus)
CLCN4/5/6 exchange Cl- for H+ (Rattus norvegicus)
H+ [endosome lumen]
Iron uptake and transport (Rattus norvegicus)
Transferrin endocytosis and recycling (Rattus norvegicus)
Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Rattus norvegicus)
H+ [endosome lumen]
Signal Transduction (Saccharomyces cerevisiae)
Signaling by Receptor Tyrosine Kinases (Saccharomyces cerevisiae)
Signaling by Insulin receptor (Saccharomyces cerevisiae)
Insulin receptor recycling (Saccharomyces cerevisiae)
Endosome acidification (Saccharomyces cerevisiae)
H+ [endosome lumen]
Transport of small molecules (Saccharomyces cerevisiae)
Ion channel transport (Saccharomyces cerevisiae)
Stimuli-sensing channels (Saccharomyces cerevisiae)
CLCN4/5/6 exchange Cl- for H+ (Saccharomyces cerevisiae)
H+ [endosome lumen]
Iron uptake and transport (Saccharomyces cerevisiae)
Transferrin endocytosis and recycling (Saccharomyces cerevisiae)
Acidification of Tf:TfR1 containing endosome (Saccharomyces cerevisiae)
H+ [endosome lumen]
Signal Transduction (Schizosaccharomyces pombe)
Signaling by Receptor Tyrosine Kinases (Schizosaccharomyces pombe)
Signaling by Insulin receptor (Schizosaccharomyces pombe)
Insulin receptor recycling (Schizosaccharomyces pombe)
Endosome acidification (Schizosaccharomyces pombe)
H+ [endosome lumen]
Transport of small molecules (Schizosaccharomyces pombe)
Ion channel transport (Schizosaccharomyces pombe)
Stimuli-sensing channels (Schizosaccharomyces pombe)
CLCN4/5/6 exchange Cl- for H+ (Schizosaccharomyces pombe)
H+ [endosome lumen]
Iron uptake and transport (Schizosaccharomyces pombe)
Transferrin endocytosis and recycling (Schizosaccharomyces pombe)
Acidification of Tf:TfR1 containing endosome (Schizosaccharomyces pombe)
H+ [endosome lumen]
Signal Transduction (Sus scrofa)
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by Insulin receptor (Sus scrofa)
Insulin receptor recycling (Sus scrofa)
Endosome acidification (Sus scrofa)
H+ [endosome lumen]
Transport of small molecules (Sus scrofa)
Ion channel transport (Sus scrofa)
Stimuli-sensing channels (Sus scrofa)
CLCN4/5/6 exchange Cl- for H+ (Sus scrofa)
H+ [endosome lumen]
Iron uptake and transport (Sus scrofa)
Transferrin endocytosis and recycling (Sus scrofa)
Acidification of Tf:TfR1 containing endosome (Sus scrofa)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Sus scrofa)
H+ [endosome lumen]
Signal Transduction (Xenopus tropicalis)
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by Insulin receptor (Xenopus tropicalis)
Insulin receptor recycling (Xenopus tropicalis)
Endosome acidification (Xenopus tropicalis)
H+ [endosome lumen]
Transport of small molecules (Xenopus tropicalis)
Ion channel transport (Xenopus tropicalis)
Stimuli-sensing channels (Xenopus tropicalis)
CLCN4/5/6 exchange Cl- for H+ (Xenopus tropicalis)
H+ [endosome lumen]
Iron uptake and transport (Xenopus tropicalis)
Transferrin endocytosis and recycling (Xenopus tropicalis)
Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
H+ [endosome lumen]
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Xenopus tropicalis)
H+ [endosome lumen]
External Reference Information
External Reference
hydron [ChEBI:15378]
Participates
as a component of
Acidified Influenza A Viral Particle Docked At The Endocytic Vesicle Membrane With An Open Pore [endocytic vesicle membrane] (Influenza A virus)
as an input of
Virion-associated M2 protein mediated ion infusion (Homo sapiens)
as an output of
CLCN4/5/6 exchange Cl- for H+ (Saccharomyces cerevisiae)
CLCN4/5/6 exchange Cl- for H+ (Schizosaccharomyces pombe)
CLCN4/5/6 exchange Cl- for H+ (Dictyostelium discoideum)
CLCN4/5/6 exchange Cl- for H+ (Caenorhabditis elegans)
CLCN4/5/6 exchange Cl- for H+ (Drosophila melanogaster)
CLCN4/5/6 exchange Cl- for H+ (Gallus gallus)
CLCN4/5/6 exchange Cl- for H+ (Xenopus tropicalis)
CLCN4/5/6 exchange Cl- for H+ (Danio rerio)
CLCN4/5/6 exchange Cl- for H+ (Sus scrofa)
Endosome acidification (Homo sapiens)
Endosome acidification (Mus musculus)
Endosome acidification (Rattus norvegicus)
Endosome acidification (Canis familiaris)
Endosome acidification (Bos taurus)
Endosome acidification (Sus scrofa)
Endosome acidification (Danio rerio)
Endosome acidification (Xenopus tropicalis)
Endosome acidification (Gallus gallus)
Endosome acidification (Drosophila melanogaster)
Endosome acidification (Caenorhabditis elegans)
Endosome acidification (Dictyostelium discoideum)
Endosome acidification (Schizosaccharomyces pombe)
Endosome acidification (Saccharomyces cerevisiae)
Endosome acidification (Plasmodium falciparum)
Acidification of Tf:TfR1 containing endosome (Sus scrofa)
Acidification of Tf:TfR1 containing endosome (Homo sapiens)
Acidification of Tf:TfR1 containing endosome (Mus musculus)
Acidification of Tf:TfR1 containing endosome (Rattus norvegicus)
Acidification of Tf:TfR1 containing endosome (Canis familiaris)
Acidification of Tf:TfR1 containing endosome (Bos taurus)
Acidification of Tf:TfR1 containing endosome (Danio rerio)
Acidification of Tf:TfR1 containing endosome (Xenopus tropicalis)
Acidification of Tf:TfR1 containing endosome (Gallus gallus)
Acidification of Tf:TfR1 containing endosome (Drosophila melanogaster)
Acidification of Tf:TfR1 containing endosome (Caenorhabditis elegans)
Acidification of Tf:TfR1 containing endosome (Dictyostelium discoideum)
Acidification of Tf:TfR1 containing endosome (Schizosaccharomyces pombe)
Acidification of Tf:TfR1 containing endosome (Saccharomyces cerevisiae)
Acidification of Tf:TfR1 containing endosome (Plasmodium falciparum)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Sus scrofa)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Homo sapiens)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Mus musculus)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Rattus norvegicus)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Canis familiaris)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Bos taurus)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Xenopus tropicalis)
STEAP3,STEAP4 reduce Fe3+ to Fe2+ (Gallus gallus)
CLCN4/5/6 exchange Cl- for H+ (Homo sapiens)
CLCN4/5/6 exchange Cl- for H+ (Mus musculus)
CLCN4/5/6 exchange Cl- for H+ (Rattus norvegicus)
CLCN4/5/6 exchange Cl- for H+ (Canis familiaris)
CLCN4/5/6 exchange Cl- for H+ (Bos taurus)
This entity regulates
Positively
pagA(197-794):ANTRX1 oligomer transports cya and lef (target cell endosome to cytosol)
(Homo sapiens)
pagA(197-794):ANTRX2 oligomer transports cya and lef (target cell endosome to cytosol)
(Homo sapiens)
Other forms of this molecule
H+ [early endosome]
H+ [synaptic vesicle lumen]
H+ [platelet dense tubular network lumen]
H+ [sperm flagellum]
H+ [phagolysosome]
H+ [cytoplasm]
H+ [phagocytic vesicle lumen]
H+ [melanosome lumen]
H+ [mitochondrial inner membrane]
H+ [synaptic vesicle]
H+ [late endosome lumen]
H+ [early endosome lumen]
H+ [lysosomal lumen]
H+ [nuclear envelope]
H+ [endocytic vesicle lumen]
H+ [Golgi lumen]
H+ [clathrin-sculpted acetylcholine transport vesicle lumen]
H+ [endolysosome lumen]
H+ [endoplasmic reticulum lumen]
H+ [endoplasmic reticulum-Golgi intermediate compartment]
H+ [extracellular region]
H+ [clathrin-sculpted monoamine transport vesicle lumen]
H+ [mitochondrial intermembrane space]
H+ [peroxisomal matrix]
H+ [mitochondrial matrix]
H+ [cytosol]
H+ [nucleoplasm]
Cross References
COMPOUND
C00080
PubChem Substance
8145820
HMDB Metabolite
HMDB0059597
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