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AMP [cytosol]
Stable Identifier
R-ALL-76577
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
adenosine 5'-monophosphate, adenosine 5'-monophosphate(2-), Adenylic acid, Adenylate, 5'-AMP, 5'-Adenylic acid, 5'-Adenosine monophosphate
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Mycobacterium tuberculosis
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
AMPK (complex) phosphorylates ULK1 (complex) (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Bos taurus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
ULK complex translocates to the ER (Bos taurus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Bos taurus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Bos taurus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Bos taurus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Drug ADME (Bos taurus)
Azathioprine ADME (Bos taurus)
GMPS dimer transforms 6TXMP to 6TGMP (Bos taurus)
AMP [cytosol]
Gene expression (Transcription) (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional Regulation by TP53 (Bos taurus)
TP53 Regulates Metabolic Genes (Bos taurus)
SESN1,2,3 bind AMPK (Bos taurus)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Class I MHC mediated antigen processing & presentation (Bos taurus)
Antigen processing: Ubiquitination & Proteasome degradation (Bos taurus)
E1 mediated ubiquitin activation (Bos taurus)
AMP [cytosol]
Polyubiquitination of substrate (Bos taurus)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
AMP [cytosol]
Cytokine Signaling in Immune system (Bos taurus)
Interferon Signaling (Bos taurus)
Antiviral mechanism by IFN-stimulated genes (Bos taurus)
ISG15 antiviral mechanism (Bos taurus)
Activation of ISG15 by UBA7 E1 ligase (Bos taurus)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Bos taurus)
AMP [cytosol]
ISGylation of IRF3 (Bos taurus)
AMP [cytosol]
ISGylation of host protein filamin B (Bos taurus)
AMP [cytosol]
ISGylation of host proteins (Bos taurus)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)
AMP [cytosol]
OAS antiviral response (Bos taurus)
PDE12 cleaves 2'-5' oligoadenylates (Bos taurus)
AMP [cytosol]
PKR-mediated signaling (Bos taurus)
ISGylation of PKR (Bos taurus)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Bos taurus)
ISGylation of DDX58 (RIG-I) (Bos taurus)
AMP [cytosol]
Metabolism (Bos taurus)
Biological oxidations (Bos taurus)
Phase I - Functionalization of compounds (Bos taurus)
Ethanol oxidation (Bos taurus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Bos taurus)
AMP [cytosol]
Phase II - Conjugation of compounds (Bos taurus)
Cytosolic sulfonation of small molecules (Bos taurus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Bos taurus)
AMP [cytosol]
Integration of energy metabolism (Bos taurus)
Regulation of insulin secretion (Bos taurus)
Free fatty acids regulate insulin secretion (Bos taurus)
Intracellular metabolism of fatty acids regulates insulin secretion (Bos taurus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Bos taurus)
AMP [cytosol]
Metabolism of amino acids and derivatives (Bos taurus)
Aspartate and asparagine metabolism (Bos taurus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Bos taurus)
AMP [cytosol]
Urea cycle (Bos taurus)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Bos taurus)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Bos taurus)
Glucose metabolism (Bos taurus)
Gluconeogenesis (Bos taurus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Bos taurus)
AMP [cytosol]
Glycolysis (Bos taurus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Bos taurus)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Bos taurus)
AMP [cytosol]
Glycogen metabolism (Bos taurus)
Glycogen breakdown (glycogenolysis) (Bos taurus)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Bos taurus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Bos taurus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Pentose phosphate pathway (Bos taurus)
5-Phosphoribose 1-diphosphate biosynthesis (Bos taurus)
PRPS dimers pyrophosphorylate R5P using ATP (Bos taurus)
AMP [cytosol]
Metabolism of lipids (Bos taurus)
Fatty acid metabolism (Bos taurus)
Fatty acyl-CoA biosynthesis (Bos taurus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Bos taurus)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Bos taurus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Bos taurus)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Bos taurus)
AMP [cytosol]
Peroxisomal lipid metabolism (Bos taurus)
Alpha-oxidation of phytanate (Bos taurus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Bos taurus)
AMP [cytosol]
Ketone body metabolism (Bos taurus)
Synthesis of Ketone Bodies (Bos taurus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Bos taurus)
AMP [cytosol]
Metabolism of steroids (Bos taurus)
Bile acid and bile salt metabolism (Bos taurus)
Recycling of bile acids and salts (Bos taurus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
AMP [cytosol]
Synthesis of bile acids and bile salts (Bos taurus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Bos taurus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Bos taurus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
AMP [cytosol]
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Bos taurus)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Bos taurus)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Bos taurus)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Bos taurus)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Bos taurus)
AMP [cytosol]
Nucleotide biosynthesis (Bos taurus)
Purine ribonucleoside monophosphate biosynthesis (Bos taurus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Bos taurus)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Bos taurus)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Bos taurus)
AMP [cytosol]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Bos taurus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Bos taurus)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Bos taurus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Bos taurus)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Bos taurus)
AMP [cytosol]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Bos taurus)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Bos taurus)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Bos taurus)
AMP [cytosol]
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of water-soluble vitamins and cofactors (Bos taurus)
Biotin transport and metabolism (Bos taurus)
HLCS biotinylates 6x(PCCA:PCCB) (Bos taurus)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Bos taurus)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Bos taurus)
AMP [cytosol]
HLCS biotinylates ACACB (Bos taurus)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Bos taurus)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Bos taurus)
Molybdenum ion transfer onto molybdopterin (Bos taurus)
AMP [cytosol]
Nicotinate metabolism (Bos taurus)
NADSYN1 hexamer amidates NAAD to NAD+ (Bos taurus)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Bos taurus)
2xTPK1:Mg2+ phosphorylates THMN (Bos taurus)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Bos taurus)
2xENPP1 hydrolyzes FAD to FMN (Bos taurus)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Bos taurus)
Coenzyme A biosynthesis (Bos taurus)
2xPPCS ligates PPanK with Cys (Bos taurus)
AMP [cytosol]
Metabolism of RNA (Bos taurus)
Deadenylation-dependent mRNA decay (Bos taurus)
Deadenylation of mRNA (Bos taurus)
CCR4-NOT complex deadenylates mRNA (Bos taurus)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Bos taurus)
AMP [cytosol]
PARN deadenylates mRNA (Bos taurus)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Bos taurus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Bos taurus)
AMP [cytosol]
Metabolism of proteins (Bos taurus)
Post-translational protein modification (Bos taurus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Bos taurus)
Synthesis of diphthamide-EEF2 (Bos taurus)
DPH6 ligates ammonium to diphthine-EEF2 (Bos taurus)
AMP [cytosol]
Neddylation (Bos taurus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Bos taurus)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Bos taurus)
AMP [cytosol]
Protein ubiquitination (Bos taurus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Bos taurus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Bos taurus)
AMP [cytosol]
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
DAG and IP3 signaling (Bos taurus)
CaM pathway (Bos taurus)
Calmodulin induced events (Bos taurus)
Cam-PDE 1 activation (Bos taurus)
cAMP hydrolysis by Cam-PDE 1 (Bos taurus)
AMP [cytosol]
MTOR signalling (Bos taurus)
Energy dependent regulation of mTOR by LKB1-AMPK (Bos taurus)
AMPK phosphorylates Raptor in the mTORC1 complex (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Bos taurus)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Bos taurus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
AMP [cytosol]
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (i) signalling events (Bos taurus)
Opioid Signalling (Bos taurus)
DARPP-32 events (Bos taurus)
PDE4A,C,D hydrolyse cAMP (Bos taurus)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Bos taurus)
AMP [cytosol]
G-protein mediated events (Bos taurus)
PLC beta mediated events (Bos taurus)
Ca-dependent events (Bos taurus)
CaM pathway (Bos taurus)
Calmodulin induced events (Bos taurus)
Cam-PDE 1 activation (Bos taurus)
cAMP hydrolysis by Cam-PDE 1 (Bos taurus)
AMP [cytosol]
G alpha (s) signalling events (Bos taurus)
PDE3A hydrolyses cAMP to AMP (Bos taurus)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Bos taurus)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Bos taurus)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Bos taurus)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by Insulin receptor (Bos taurus)
Insulin receptor signalling cascade (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
PKB-mediated events (Bos taurus)
PDE3B signalling (Bos taurus)
p-S295-PDE3B hydrolyses cAMP to AMP (Bos taurus)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Bos taurus)
IGF1R signaling cascade (Bos taurus)
IRS-related events triggered by IGF1R (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
PKB-mediated events (Bos taurus)
PDE3B signalling (Bos taurus)
p-S295-PDE3B hydrolyses cAMP to AMP (Bos taurus)
AMP [cytosol]
Autophagy (Caenorhabditis elegans)
Macroautophagy (Caenorhabditis elegans)
AMPK (complex) phosphorylates ULK1 (complex) (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
ULK complex translocates to the ER (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Drug ADME (Caenorhabditis elegans)
Azathioprine ADME (Caenorhabditis elegans)
GMPS dimer transforms 6TXMP to 6TGMP (Caenorhabditis elegans)
AMP [cytosol]
Gene expression (Transcription) (Caenorhabditis elegans)
RNA Polymerase II Transcription (Caenorhabditis elegans)
Generic Transcription Pathway (Caenorhabditis elegans)
Transcriptional Regulation by TP53 (Caenorhabditis elegans)
TP53 Regulates Metabolic Genes (Caenorhabditis elegans)
SESN1,2,3 bind AMPK (Caenorhabditis elegans)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Immune System (Caenorhabditis elegans)
Adaptive Immune System (Caenorhabditis elegans)
Class I MHC mediated antigen processing & presentation (Caenorhabditis elegans)
Antigen processing: Ubiquitination & Proteasome degradation (Caenorhabditis elegans)
E1 mediated ubiquitin activation (Caenorhabditis elegans)
AMP [cytosol]
Polyubiquitination of substrate (Caenorhabditis elegans)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
AMP [cytosol]
Cytokine Signaling in Immune system (Caenorhabditis elegans)
Interferon Signaling (Caenorhabditis elegans)
Antiviral mechanism by IFN-stimulated genes (Caenorhabditis elegans)
ISG15 antiviral mechanism (Caenorhabditis elegans)
Activation of ISG15 by UBA7 E1 ligase (Caenorhabditis elegans)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Caenorhabditis elegans)
AMP [cytosol]
ISGylation of host protein filamin B (Caenorhabditis elegans)
AMP [cytosol]
ISGylation of host proteins (Caenorhabditis elegans)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Caenorhabditis elegans)
AMP [cytosol]
OAS antiviral response (Caenorhabditis elegans)
PDE12 cleaves 2'-5' oligoadenylates (Caenorhabditis elegans)
AMP [cytosol]
PKR-mediated signaling (Caenorhabditis elegans)
ISGylation of PKR (Caenorhabditis elegans)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Caenorhabditis elegans)
ISGylation of DDX58 (RIG-I) (Caenorhabditis elegans)
AMP [cytosol]
Metabolism (Caenorhabditis elegans)
Biological oxidations (Caenorhabditis elegans)
Phase I - Functionalization of compounds (Caenorhabditis elegans)
Ethanol oxidation (Caenorhabditis elegans)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Caenorhabditis elegans)
AMP [cytosol]
Phase II - Conjugation of compounds (Caenorhabditis elegans)
Cytosolic sulfonation of small molecules (Caenorhabditis elegans)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Caenorhabditis elegans)
AMP [cytosol]
Integration of energy metabolism (Caenorhabditis elegans)
Regulation of insulin secretion (Caenorhabditis elegans)
Free fatty acids regulate insulin secretion (Caenorhabditis elegans)
Intracellular metabolism of fatty acids regulates insulin secretion (Caenorhabditis elegans)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Aspartate and asparagine metabolism (Caenorhabditis elegans)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Caenorhabditis elegans)
AMP [cytosol]
Selenoamino acid metabolism (Caenorhabditis elegans)
Selenocysteine synthesis (Caenorhabditis elegans)
SEPHS2 phosphorylates H2Se to form SELP (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Caenorhabditis elegans)
Glucose metabolism (Caenorhabditis elegans)
Gluconeogenesis (Caenorhabditis elegans)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Caenorhabditis elegans)
AMP [cytosol]
Glycolysis (Caenorhabditis elegans)
ADPGK:Mg2+ phosphorylates Glc to G6P (Caenorhabditis elegans)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Caenorhabditis elegans)
AMP [cytosol]
Glycogen metabolism (Caenorhabditis elegans)
Glycogen breakdown (glycogenolysis) (Caenorhabditis elegans)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Caenorhabditis elegans)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Caenorhabditis elegans)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of lipids (Caenorhabditis elegans)
Fatty acid metabolism (Caenorhabditis elegans)
Fatty acyl-CoA biosynthesis (Caenorhabditis elegans)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Caenorhabditis elegans)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Caenorhabditis elegans)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Caenorhabditis elegans)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Caenorhabditis elegans)
AMP [cytosol]
Ketone body metabolism (Caenorhabditis elegans)
Synthesis of Ketone Bodies (Caenorhabditis elegans)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of steroids (Caenorhabditis elegans)
Bile acid and bile salt metabolism (Caenorhabditis elegans)
Recycling of bile acids and salts (Caenorhabditis elegans)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
AMP [cytosol]
Synthesis of bile acids and bile salts (Caenorhabditis elegans)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Caenorhabditis elegans)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Caenorhabditis elegans)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Caenorhabditis elegans)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Caenorhabditis elegans)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Caenorhabditis elegans)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Caenorhabditis elegans)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Caenorhabditis elegans)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Caenorhabditis elegans)
AMP [cytosol]
Nucleotide biosynthesis (Caenorhabditis elegans)
Purine ribonucleoside monophosphate biosynthesis (Caenorhabditis elegans)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Caenorhabditis elegans)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Caenorhabditis elegans)
AMP [cytosol]
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
Phosphate bond hydrolysis by NUDT proteins (Caenorhabditis elegans)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Caenorhabditis elegans)
AMP [cytosol]
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Caenorhabditis elegans)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Caenorhabditis elegans)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of vitamins and cofactors (Caenorhabditis elegans)
Metabolism of water-soluble vitamins and cofactors (Caenorhabditis elegans)
Biotin transport and metabolism (Caenorhabditis elegans)
HLCS biotinylates 6x(PCCA:PCCB) (Caenorhabditis elegans)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Caenorhabditis elegans)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Caenorhabditis elegans)
AMP [cytosol]
HLCS biotinylates ACACB (Caenorhabditis elegans)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Caenorhabditis elegans)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Caenorhabditis elegans)
Molybdenum ion transfer onto molybdopterin (Caenorhabditis elegans)
AMP [cytosol]
Nicotinate metabolism (Caenorhabditis elegans)
NADSYN1 hexamer amidates NAAD to NAD+ (Caenorhabditis elegans)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Caenorhabditis elegans)
2xTPK1:Mg2+ phosphorylates THMN (Caenorhabditis elegans)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Caenorhabditis elegans)
2xENPP1 hydrolyzes FAD to FMN (Caenorhabditis elegans)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Caenorhabditis elegans)
Coenzyme A biosynthesis (Caenorhabditis elegans)
2xPPCS ligates PPanK with Cys (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of RNA (Caenorhabditis elegans)
Deadenylation-dependent mRNA decay (Caenorhabditis elegans)
mRNA decay by 3' to 5' exoribonuclease (Caenorhabditis elegans)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Caenorhabditis elegans)
AMP [cytosol]
Metabolism of proteins (Caenorhabditis elegans)
Post-translational protein modification (Caenorhabditis elegans)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Caenorhabditis elegans)
Synthesis of diphthamide-EEF2 (Caenorhabditis elegans)
DPH6 ligates ammonium to diphthine-EEF2 (Caenorhabditis elegans)
AMP [cytosol]
Neddylation (Caenorhabditis elegans)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Caenorhabditis elegans)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Caenorhabditis elegans)
AMP [cytosol]
Protein ubiquitination (Caenorhabditis elegans)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Caenorhabditis elegans)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Caenorhabditis elegans)
AMP [cytosol]
Signal Transduction (Caenorhabditis elegans)
Intracellular signaling by second messengers (Caenorhabditis elegans)
DAG and IP3 signaling (Caenorhabditis elegans)
CaM pathway (Caenorhabditis elegans)
Calmodulin induced events (Caenorhabditis elegans)
Cam-PDE 1 activation (Caenorhabditis elegans)
cAMP hydrolysis by Cam-PDE 1 (Caenorhabditis elegans)
AMP [cytosol]
MTOR signalling (Caenorhabditis elegans)
Energy dependent regulation of mTOR by LKB1-AMPK (Caenorhabditis elegans)
AMPK phosphorylates Raptor in the mTORC1 complex (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Caenorhabditis elegans)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
AMP [cytosol]
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (i) signalling events (Caenorhabditis elegans)
Opioid Signalling (Caenorhabditis elegans)
DARPP-32 events (Caenorhabditis elegans)
PDE4A,C,D hydrolyse cAMP (Caenorhabditis elegans)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Caenorhabditis elegans)
AMP [cytosol]
G-protein mediated events (Caenorhabditis elegans)
PLC beta mediated events (Caenorhabditis elegans)
Ca-dependent events (Caenorhabditis elegans)
CaM pathway (Caenorhabditis elegans)
Calmodulin induced events (Caenorhabditis elegans)
Cam-PDE 1 activation (Caenorhabditis elegans)
cAMP hydrolysis by Cam-PDE 1 (Caenorhabditis elegans)
AMP [cytosol]
G alpha (s) signalling events (Caenorhabditis elegans)
PDE3A hydrolyses cAMP to AMP (Caenorhabditis elegans)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Caenorhabditis elegans)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Caenorhabditis elegans)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Caenorhabditis elegans)
Signaling by Insulin receptor (Caenorhabditis elegans)
Insulin receptor signalling cascade (Caenorhabditis elegans)
IRS-mediated signalling (Caenorhabditis elegans)
PI3K Cascade (Caenorhabditis elegans)
PKB-mediated events (Caenorhabditis elegans)
PDE3B signalling (Caenorhabditis elegans)
p-S295-PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Caenorhabditis elegans)
IGF1R signaling cascade (Caenorhabditis elegans)
IRS-related events triggered by IGF1R (Caenorhabditis elegans)
IRS-mediated signalling (Caenorhabditis elegans)
PI3K Cascade (Caenorhabditis elegans)
PKB-mediated events (Caenorhabditis elegans)
PDE3B signalling (Caenorhabditis elegans)
p-S295-PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)
AMP [cytosol]
Autophagy (Canis familiaris)
Macroautophagy (Canis familiaris)
AMPK (complex) phosphorylates ULK1 (complex) (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Canis familiaris)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
ULK complex translocates to the ER (Canis familiaris)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Canis familiaris)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Canis familiaris)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Canis familiaris)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Drug ADME (Canis familiaris)
Azathioprine ADME (Canis familiaris)
GMPS dimer transforms 6TXMP to 6TGMP (Canis familiaris)
AMP [cytosol]
Gene expression (Transcription) (Canis familiaris)
RNA Polymerase II Transcription (Canis familiaris)
Generic Transcription Pathway (Canis familiaris)
Transcriptional Regulation by TP53 (Canis familiaris)
TP53 Regulates Metabolic Genes (Canis familiaris)
SESN1,2,3 bind AMPK (Canis familiaris)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Immune System (Canis familiaris)
Adaptive Immune System (Canis familiaris)
Class I MHC mediated antigen processing & presentation (Canis familiaris)
Antigen processing: Ubiquitination & Proteasome degradation (Canis familiaris)
E1 mediated ubiquitin activation (Canis familiaris)
AMP [cytosol]
Polyubiquitination of substrate (Canis familiaris)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Canis familiaris)
AMP [cytosol]
Cytokine Signaling in Immune system (Canis familiaris)
Interferon Signaling (Canis familiaris)
Antiviral mechanism by IFN-stimulated genes (Canis familiaris)
ISG15 antiviral mechanism (Canis familiaris)
Activation of ISG15 by UBA7 E1 ligase (Canis familiaris)
AMP [cytosol]
OAS antiviral response (Canis familiaris)
PDE12 cleaves 2'-5' oligoadenylates (Canis familiaris)
AMP [cytosol]
Innate Immune System (Canis familiaris)
C-type lectin receptors (CLRs) (Canis familiaris)
CLEC7A (Dectin-1) signaling (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
AMP [cytosol]
TRAF6 oligomer autoubiquitinates (Canis familiaris)
AMP [cytosol]
Fc epsilon receptor (FCERI) signaling (Canis familiaris)
FCERI mediated NF-kB activation (Canis familiaris)
Auto-ubiquitination of TRAF6 (Canis familiaris)
AMP [cytosol]
Metabolism (Canis familiaris)
Biological oxidations (Canis familiaris)
Phase I - Functionalization of compounds (Canis familiaris)
Ethanol oxidation (Canis familiaris)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Canis familiaris)
AMP [cytosol]
Phase II - Conjugation of compounds (Canis familiaris)
Cytosolic sulfonation of small molecules (Canis familiaris)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Canis familiaris)
AMP [cytosol]
Integration of energy metabolism (Canis familiaris)
Regulation of insulin secretion (Canis familiaris)
Free fatty acids regulate insulin secretion (Canis familiaris)
Intracellular metabolism of fatty acids regulates insulin secretion (Canis familiaris)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)
AMP [cytosol]
Metabolism of amino acids and derivatives (Canis familiaris)
Aspartate and asparagine metabolism (Canis familiaris)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Canis familiaris)
AMP [cytosol]
Selenoamino acid metabolism (Canis familiaris)
Selenocysteine synthesis (Canis familiaris)
SEPHS2 phosphorylates H2Se to form SELP (Canis familiaris)
AMP [cytosol]
Urea cycle (Canis familiaris)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Canis familiaris)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Canis familiaris)
Glucose metabolism (Canis familiaris)
Gluconeogenesis (Canis familiaris)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Canis familiaris)
AMP [cytosol]
Glycolysis (Canis familiaris)
ADPGK:Mg2+ phosphorylates Glc to G6P (Canis familiaris)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Canis familiaris)
AMP [cytosol]
Glycogen metabolism (Canis familiaris)
Glycogen breakdown (glycogenolysis) (Canis familiaris)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Canis familiaris)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Canis familiaris)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Pentose phosphate pathway (Canis familiaris)
5-Phosphoribose 1-diphosphate biosynthesis (Canis familiaris)
PRPS dimers pyrophosphorylate R5P using ATP (Canis familiaris)
AMP [cytosol]
Metabolism of lipids (Canis familiaris)
Fatty acid metabolism (Canis familiaris)
Fatty acyl-CoA biosynthesis (Canis familiaris)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Canis familiaris)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Canis familiaris)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Canis familiaris)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Canis familiaris)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Canis familiaris)
AMP [cytosol]
Peroxisomal lipid metabolism (Canis familiaris)
Alpha-oxidation of phytanate (Canis familiaris)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Canis familiaris)
AMP [cytosol]
Metabolism of steroids (Canis familiaris)
Bile acid and bile salt metabolism (Canis familiaris)
Recycling of bile acids and salts (Canis familiaris)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
AMP [cytosol]
Synthesis of bile acids and bile salts (Canis familiaris)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Canis familiaris)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Canis familiaris)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
AMP [cytosol]
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Canis familiaris)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Canis familiaris)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Canis familiaris)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Canis familiaris)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Canis familiaris)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Canis familiaris)
AMP [cytosol]
Nucleotide biosynthesis (Canis familiaris)
Purine ribonucleoside monophosphate biosynthesis (Canis familiaris)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Canis familiaris)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Canis familiaris)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Canis familiaris)
AMP [cytosol]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Canis familiaris)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Canis familiaris)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Canis familiaris)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Canis familiaris)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Canis familiaris)
AMP [cytosol]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Canis familiaris)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Canis familiaris)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Canis familiaris)
AMP [cytosol]
Metabolism of vitamins and cofactors (Canis familiaris)
Metabolism of water-soluble vitamins and cofactors (Canis familiaris)
Biotin transport and metabolism (Canis familiaris)
HLCS biotinylates 6x(PCCA:PCCB) (Canis familiaris)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Canis familiaris)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Canis familiaris)
AMP [cytosol]
HLCS biotinylates ACACB (Canis familiaris)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Canis familiaris)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Canis familiaris)
Molybdenum ion transfer onto molybdopterin (Canis familiaris)
AMP [cytosol]
Nicotinate metabolism (Canis familiaris)
NADSYN1 hexamer amidates NAAD to NAD+ (Canis familiaris)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Canis familiaris)
2xTPK1:Mg2+ phosphorylates THMN (Canis familiaris)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Canis familiaris)
2xENPP1 hydrolyzes FAD to FMN (Canis familiaris)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Canis familiaris)
Coenzyme A biosynthesis (Canis familiaris)
2xPPCS ligates PPanK with Cys (Canis familiaris)
AMP [cytosol]
Metabolism of RNA (Canis familiaris)
Deadenylation-dependent mRNA decay (Canis familiaris)
Deadenylation of mRNA (Canis familiaris)
CCR4-NOT complex deadenylates mRNA (Canis familiaris)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Canis familiaris)
AMP [cytosol]
PARN deadenylates mRNA (Canis familiaris)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Canis familiaris)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Canis familiaris)
AMP [cytosol]
Metabolism of proteins (Canis familiaris)
Post-translational protein modification (Canis familiaris)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Canis familiaris)
Synthesis of diphthamide-EEF2 (Canis familiaris)
DPH6 ligates ammonium to diphthine-EEF2 (Canis familiaris)
AMP [cytosol]
Neddylation (Canis familiaris)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Canis familiaris)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Canis familiaris)
AMP [cytosol]
Protein ubiquitination (Canis familiaris)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Canis familiaris)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Canis familiaris)
AMP [cytosol]
Signal Transduction (Canis familiaris)
Intracellular signaling by second messengers (Canis familiaris)
DAG and IP3 signaling (Canis familiaris)
CaM pathway (Canis familiaris)
Calmodulin induced events (Canis familiaris)
Cam-PDE 1 activation (Canis familiaris)
cAMP hydrolysis by Cam-PDE 1 (Canis familiaris)
AMP [cytosol]
MTOR signalling (Canis familiaris)
Energy dependent regulation of mTOR by LKB1-AMPK (Canis familiaris)
AMPK phosphorylates Raptor in the mTORC1 complex (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Canis familiaris)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Canis familiaris)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
AMP [cytosol]
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (i) signalling events (Canis familiaris)
Opioid Signalling (Canis familiaris)
DARPP-32 events (Canis familiaris)
PDE4A,C,D hydrolyse cAMP (Canis familiaris)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Canis familiaris)
AMP [cytosol]
G-protein mediated events (Canis familiaris)
PLC beta mediated events (Canis familiaris)
Ca-dependent events (Canis familiaris)
CaM pathway (Canis familiaris)
Calmodulin induced events (Canis familiaris)
Cam-PDE 1 activation (Canis familiaris)
cAMP hydrolysis by Cam-PDE 1 (Canis familiaris)
AMP [cytosol]
G alpha (s) signalling events (Canis familiaris)
PDE3A hydrolyses cAMP to AMP (Canis familiaris)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Canis familiaris)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Canis familiaris)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Canis familiaris)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Canis familiaris)
Signaling by Insulin receptor (Canis familiaris)
Insulin receptor signalling cascade (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PKB-mediated events (Canis familiaris)
PDE3B signalling (Canis familiaris)
p-S295-PDE3B hydrolyses cAMP to AMP (Canis familiaris)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Canis familiaris)
IGF1R signaling cascade (Canis familiaris)
IRS-related events triggered by IGF1R (Canis familiaris)
IRS-mediated signalling (Canis familiaris)
PI3K Cascade (Canis familiaris)
PKB-mediated events (Canis familiaris)
PDE3B signalling (Canis familiaris)
p-S295-PDE3B hydrolyses cAMP to AMP (Canis familiaris)
AMP [cytosol]
Autophagy (Danio rerio)
Macroautophagy (Danio rerio)
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Danio rerio)
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
Gene expression (Transcription) (Danio rerio)
RNA Polymerase II Transcription (Danio rerio)
Generic Transcription Pathway (Danio rerio)
Transcriptional Regulation by TP53 (Danio rerio)
TP53 Regulates Metabolic Genes (Danio rerio)
SESN1,2,3 bind AMPK (Danio rerio)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
Immune System (Danio rerio)
Adaptive Immune System (Danio rerio)
Class I MHC mediated antigen processing & presentation (Danio rerio)
Antigen processing: Ubiquitination & Proteasome degradation (Danio rerio)
E1 mediated ubiquitin activation (Danio rerio)
AMP [cytosol]
Polyubiquitination of substrate (Danio rerio)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Danio rerio)
AMP [cytosol]
Metabolism (Danio rerio)
Integration of energy metabolism (Danio rerio)
Regulation of insulin secretion (Danio rerio)
Free fatty acids regulate insulin secretion (Danio rerio)
Intracellular metabolism of fatty acids regulates insulin secretion (Danio rerio)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Danio rerio)
AMP [cytosol]
Metabolism of amino acids and derivatives (Danio rerio)
Selenoamino acid metabolism (Danio rerio)
Selenocysteine synthesis (Danio rerio)
SEPHS2 phosphorylates H2Se to form SELP (Danio rerio)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Danio rerio)
Glucose metabolism (Danio rerio)
Gluconeogenesis (Danio rerio)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Danio rerio)
AMP [cytosol]
Glycolysis (Danio rerio)
ADPGK:Mg2+ phosphorylates Glc to G6P (Danio rerio)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Danio rerio)
AMP [cytosol]
Glycogen metabolism (Danio rerio)
Glycogen breakdown (glycogenolysis) (Danio rerio)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Danio rerio)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Danio rerio)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
Pentose phosphate pathway (Danio rerio)
5-Phosphoribose 1-diphosphate biosynthesis (Danio rerio)
PRPS dimers pyrophosphorylate R5P using ATP (Danio rerio)
AMP [cytosol]
Metabolism of lipids (Danio rerio)
Fatty acid metabolism (Danio rerio)
Fatty acyl-CoA biosynthesis (Danio rerio)
Synthesis of very long-chain fatty acyl-CoAs (Danio rerio)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Danio rerio)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Danio rerio)
AMP [cytosol]
Ketone body metabolism (Danio rerio)
Synthesis of Ketone Bodies (Danio rerio)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Danio rerio)
AMP [cytosol]
Metabolism of steroids (Danio rerio)
Bile acid and bile salt metabolism (Danio rerio)
Recycling of bile acids and salts (Danio rerio)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
AMP [cytosol]
Synthesis of bile acids and bile salts (Danio rerio)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Danio rerio)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Danio rerio)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
AMP [cytosol]
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Danio rerio)
(d)NMPs [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Danio rerio)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Danio rerio)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Danio rerio)
AMP [cytosol]
Nucleotide biosynthesis (Danio rerio)
Purine ribonucleoside monophosphate biosynthesis (Danio rerio)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Danio rerio)
AMP [cytosol]
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Danio rerio)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Danio rerio)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Danio rerio)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Danio rerio)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Danio rerio)
AMP [cytosol]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Danio rerio)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Danio rerio)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Danio rerio)
AMP [cytosol]
Metabolism of vitamins and cofactors (Danio rerio)
Metabolism of water-soluble vitamins and cofactors (Danio rerio)
Nicotinate metabolism (Danio rerio)
NADSYN1 hexamer amidates NAAD to NAD+ (Danio rerio)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Danio rerio)
2xTPK1:Mg2+ phosphorylates THMN (Danio rerio)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Danio rerio)
2xENPP1 hydrolyzes FAD to FMN (Danio rerio)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Danio rerio)
Coenzyme A biosynthesis (Danio rerio)
2xPPCS ligates PPanK with Cys (Danio rerio)
AMP [cytosol]
Metabolism of proteins (Danio rerio)
Post-translational protein modification (Danio rerio)
Neddylation (Danio rerio)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Danio rerio)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Danio rerio)
AMP [cytosol]
Protein ubiquitination (Danio rerio)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Danio rerio)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Danio rerio)
AMP [cytosol]
Signal Transduction (Danio rerio)
MTOR signalling (Danio rerio)
Energy dependent regulation of mTOR by LKB1-AMPK (Danio rerio)
AMPK phosphorylates Raptor in the mTORC1 complex (Danio rerio)
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Danio rerio)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
AMP [cytosol]
Signaling by GPCR (Danio rerio)
GPCR downstream signalling (Danio rerio)
G alpha (s) signalling events (Danio rerio)
cAMP degradation by Phosphodiesterases (Danio rerio)
AMP [cytosol]
Autophagy (Dictyostelium discoideum)
Macroautophagy (Dictyostelium discoideum)
AMPK (complex) phosphorylates ULK1 (complex) (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
ULK complex translocates to the ER (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Drug ADME (Dictyostelium discoideum)
Azathioprine ADME (Dictyostelium discoideum)
GMPS dimer transforms 6TXMP to 6TGMP (Dictyostelium discoideum)
AMP [cytosol]
Gene expression (Transcription) (Dictyostelium discoideum)
RNA Polymerase II Transcription (Dictyostelium discoideum)
Generic Transcription Pathway (Dictyostelium discoideum)
Transcriptional Regulation by TP53 (Dictyostelium discoideum)
TP53 Regulates Metabolic Genes (Dictyostelium discoideum)
SESN1,2,3 bind AMPK (Dictyostelium discoideum)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Immune System (Dictyostelium discoideum)
Adaptive Immune System (Dictyostelium discoideum)
Class I MHC mediated antigen processing & presentation (Dictyostelium discoideum)
Antigen processing: Ubiquitination & Proteasome degradation (Dictyostelium discoideum)
E1 mediated ubiquitin activation (Dictyostelium discoideum)
AMP [cytosol]
Polyubiquitination of substrate (Dictyostelium discoideum)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Dictyostelium discoideum)
AMP [cytosol]
Cytokine Signaling in Immune system (Dictyostelium discoideum)
Interferon Signaling (Dictyostelium discoideum)
Antiviral mechanism by IFN-stimulated genes (Dictyostelium discoideum)
ISG15 antiviral mechanism (Dictyostelium discoideum)
Activation of ISG15 by UBA7 E1 ligase (Dictyostelium discoideum)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Dictyostelium discoideum)
AMP [cytosol]
ISGylation of host protein filamin B (Dictyostelium discoideum)
AMP [cytosol]
ISGylation of host proteins (Dictyostelium discoideum)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Dictyostelium discoideum)
ISGylation of DDX58 (RIG-I) (Dictyostelium discoideum)
AMP [cytosol]
Metabolism (Dictyostelium discoideum)
Biological oxidations (Dictyostelium discoideum)
Phase I - Functionalization of compounds (Dictyostelium discoideum)
Ethanol oxidation (Dictyostelium discoideum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Dictyostelium discoideum)
AMP [cytosol]
Phase II - Conjugation of compounds (Dictyostelium discoideum)
Cytosolic sulfonation of small molecules (Dictyostelium discoideum)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Aspartate and asparagine metabolism (Dictyostelium discoideum)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Dictyostelium discoideum)
AMP [cytosol]
Selenoamino acid metabolism (Dictyostelium discoideum)
Selenocysteine synthesis (Dictyostelium discoideum)
SEPHS2 phosphorylates H2Se to form SELP (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Dictyostelium discoideum)
Glucose metabolism (Dictyostelium discoideum)
Gluconeogenesis (Dictyostelium discoideum)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Dictyostelium discoideum)
AMP [cytosol]
Glycolysis (Dictyostelium discoideum)
ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)
AMP [cytosol]
Glycogen metabolism (Dictyostelium discoideum)
Glycogen breakdown (glycogenolysis) (Dictyostelium discoideum)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Dictyostelium discoideum)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Dictyostelium discoideum)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Pentose phosphate pathway (Dictyostelium discoideum)
5-Phosphoribose 1-diphosphate biosynthesis (Dictyostelium discoideum)
PRPS dimers pyrophosphorylate R5P using ATP (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of lipids (Dictyostelium discoideum)
Fatty acid metabolism (Dictyostelium discoideum)
Fatty acyl-CoA biosynthesis (Dictyostelium discoideum)
Synthesis of very long-chain fatty acyl-CoAs (Dictyostelium discoideum)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Dictyostelium discoideum)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Dictyostelium discoideum)
AMP [cytosol]
Peroxisomal lipid metabolism (Dictyostelium discoideum)
Alpha-oxidation of phytanate (Dictyostelium discoideum)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
ADP + ADP <=> AMP + ATP [AK2] (Dictyostelium discoideum)
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Dictyostelium discoideum)
AMP [cytosol]
Nucleotide biosynthesis (Dictyostelium discoideum)
Purine ribonucleoside monophosphate biosynthesis (Dictyostelium discoideum)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Dictyostelium discoideum)
AMP [cytosol]
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
Phosphate bond hydrolysis by NUDT proteins (Dictyostelium discoideum)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Dictyostelium discoideum)
AMP [cytosol]
Nucleotide salvage (Dictyostelium discoideum)
Purine salvage (Dictyostelium discoideum)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Dictyostelium discoideum)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of vitamins and cofactors (Dictyostelium discoideum)
Metabolism of water-soluble vitamins and cofactors (Dictyostelium discoideum)
Biotin transport and metabolism (Dictyostelium discoideum)
HLCS biotinylates 6x(PCCA:PCCB) (Dictyostelium discoideum)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Dictyostelium discoideum)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Dictyostelium discoideum)
AMP [cytosol]
HLCS biotinylates ACACB (Dictyostelium discoideum)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Dictyostelium discoideum)
Molybdenum ion transfer onto molybdopterin (Dictyostelium discoideum)
AMP [cytosol]
Nicotinate metabolism (Dictyostelium discoideum)
NADSYN1 hexamer amidates NAAD to NAD+ (Dictyostelium discoideum)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Dictyostelium discoideum)
2xTPK1:Mg2+ phosphorylates THMN (Dictyostelium discoideum)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Dictyostelium discoideum)
2xENPP1 hydrolyzes FAD to FMN (Dictyostelium discoideum)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Dictyostelium discoideum)
Coenzyme A biosynthesis (Dictyostelium discoideum)
2xPPCS ligates PPanK with Cys (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of RNA (Dictyostelium discoideum)
Deadenylation-dependent mRNA decay (Dictyostelium discoideum)
mRNA decay by 3' to 5' exoribonuclease (Dictyostelium discoideum)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Dictyostelium discoideum)
AMP [cytosol]
Metabolism of proteins (Dictyostelium discoideum)
Post-translational protein modification (Dictyostelium discoideum)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Dictyostelium discoideum)
Synthesis of diphthamide-EEF2 (Dictyostelium discoideum)
DPH6 ligates ammonium to diphthine-EEF2 (Dictyostelium discoideum)
AMP [cytosol]
Neddylation (Dictyostelium discoideum)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Dictyostelium discoideum)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Dictyostelium discoideum)
AMP [cytosol]
Protein ubiquitination (Dictyostelium discoideum)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Dictyostelium discoideum)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Dictyostelium discoideum)
AMP [cytosol]
Signal Transduction (Dictyostelium discoideum)
Intracellular signaling by second messengers (Dictyostelium discoideum)
DAG and IP3 signaling (Dictyostelium discoideum)
CaM pathway (Dictyostelium discoideum)
Calmodulin induced events (Dictyostelium discoideum)
Cam-PDE 1 activation (Dictyostelium discoideum)
cAMP hydrolysis by Cam-PDE 1 (Dictyostelium discoideum)
AMP [cytosol]
MTOR signalling (Dictyostelium discoideum)
Energy dependent regulation of mTOR by LKB1-AMPK (Dictyostelium discoideum)
AMPK phosphorylates Raptor in the mTORC1 complex (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Dictyostelium discoideum)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
AMP [cytosol]
Signaling by GPCR (Dictyostelium discoideum)
GPCR downstream signalling (Dictyostelium discoideum)
G alpha (i) signalling events (Dictyostelium discoideum)
Opioid Signalling (Dictyostelium discoideum)
DARPP-32 events (Dictyostelium discoideum)
PDE4A,C,D hydrolyse cAMP (Dictyostelium discoideum)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Dictyostelium discoideum)
AMP [cytosol]
G-protein mediated events (Dictyostelium discoideum)
PLC beta mediated events (Dictyostelium discoideum)
Ca-dependent events (Dictyostelium discoideum)
CaM pathway (Dictyostelium discoideum)
Calmodulin induced events (Dictyostelium discoideum)
Cam-PDE 1 activation (Dictyostelium discoideum)
cAMP hydrolysis by Cam-PDE 1 (Dictyostelium discoideum)
AMP [cytosol]
G alpha (s) signalling events (Dictyostelium discoideum)
PDE3A hydrolyses cAMP to AMP (Dictyostelium discoideum)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Dictyostelium discoideum)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Dictyostelium discoideum)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Dictyostelium discoideum)
Signaling by Insulin receptor (Dictyostelium discoideum)
Insulin receptor signalling cascade (Dictyostelium discoideum)
IRS-mediated signalling (Dictyostelium discoideum)
PI3K Cascade (Dictyostelium discoideum)
PKB-mediated events (Dictyostelium discoideum)
PDE3B signalling (Dictyostelium discoideum)
p-S295-PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Dictyostelium discoideum)
IGF1R signaling cascade (Dictyostelium discoideum)
IRS-related events triggered by IGF1R (Dictyostelium discoideum)
IRS-mediated signalling (Dictyostelium discoideum)
PI3K Cascade (Dictyostelium discoideum)
PKB-mediated events (Dictyostelium discoideum)
PDE3B signalling (Dictyostelium discoideum)
p-S295-PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)
AMP [cytosol]
Autophagy (Drosophila melanogaster)
Macroautophagy (Drosophila melanogaster)
AMPK (complex) phosphorylates ULK1 (complex) (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Drosophila melanogaster)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
ULK complex translocates to the ER (Drosophila melanogaster)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Drosophila melanogaster)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Drosophila melanogaster)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Drosophila melanogaster)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Drug ADME (Drosophila melanogaster)
Azathioprine ADME (Drosophila melanogaster)
GMPS dimer transforms 6TXMP to 6TGMP (Drosophila melanogaster)
AMP [cytosol]
Gene expression (Transcription) (Drosophila melanogaster)
RNA Polymerase II Transcription (Drosophila melanogaster)
Generic Transcription Pathway (Drosophila melanogaster)
Transcriptional Regulation by TP53 (Drosophila melanogaster)
TP53 Regulates Metabolic Genes (Drosophila melanogaster)
SESN1,2,3 bind AMPK (Drosophila melanogaster)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Immune System (Drosophila melanogaster)
Adaptive Immune System (Drosophila melanogaster)
Class I MHC mediated antigen processing & presentation (Drosophila melanogaster)
Antigen processing: Ubiquitination & Proteasome degradation (Drosophila melanogaster)
E1 mediated ubiquitin activation (Drosophila melanogaster)
AMP [cytosol]
Polyubiquitination of substrate (Drosophila melanogaster)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
AMP [cytosol]
Cytokine Signaling in Immune system (Drosophila melanogaster)
Interferon Signaling (Drosophila melanogaster)
Antiviral mechanism by IFN-stimulated genes (Drosophila melanogaster)
ISG15 antiviral mechanism (Drosophila melanogaster)
Activation of ISG15 by UBA7 E1 ligase (Drosophila melanogaster)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Drosophila melanogaster)
AMP [cytosol]
ISGylation of host protein filamin B (Drosophila melanogaster)
AMP [cytosol]
ISGylation of host proteins (Drosophila melanogaster)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Drosophila melanogaster)
AMP [cytosol]
OAS antiviral response (Drosophila melanogaster)
PDE12 cleaves 2'-5' oligoadenylates (Drosophila melanogaster)
AMP [cytosol]
PKR-mediated signaling (Drosophila melanogaster)
ISGylation of PKR (Drosophila melanogaster)
AMP [cytosol]
Metabolism (Drosophila melanogaster)
Biological oxidations (Drosophila melanogaster)
Phase I - Functionalization of compounds (Drosophila melanogaster)
Ethanol oxidation (Drosophila melanogaster)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Drosophila melanogaster)
AMP [cytosol]
Phase II - Conjugation of compounds (Drosophila melanogaster)
Cytosolic sulfonation of small molecules (Drosophila melanogaster)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Drosophila melanogaster)
AMP [cytosol]
Integration of energy metabolism (Drosophila melanogaster)
Regulation of insulin secretion (Drosophila melanogaster)
Free fatty acids regulate insulin secretion (Drosophila melanogaster)
Intracellular metabolism of fatty acids regulates insulin secretion (Drosophila melanogaster)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Drosophila melanogaster)
AMP [cytosol]
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Selenoamino acid metabolism (Drosophila melanogaster)
Selenocysteine synthesis (Drosophila melanogaster)
SEPHS2 phosphorylates H2Se to form SELP (Drosophila melanogaster)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Drosophila melanogaster)
Glucose metabolism (Drosophila melanogaster)
Gluconeogenesis (Drosophila melanogaster)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Drosophila melanogaster)
AMP [cytosol]
Glycolysis (Drosophila melanogaster)
PFK tetramer phosphorylates Fru(6)P (Drosophila melanogaster)
AMP [cytosol]
Glycogen metabolism (Drosophila melanogaster)
Glycogen breakdown (glycogenolysis) (Drosophila melanogaster)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Drosophila melanogaster)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Drosophila melanogaster)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Metabolism of lipids (Drosophila melanogaster)
Fatty acid metabolism (Drosophila melanogaster)
Fatty acyl-CoA biosynthesis (Drosophila melanogaster)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Drosophila melanogaster)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Drosophila melanogaster)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Drosophila melanogaster)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Drosophila melanogaster)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Drosophila melanogaster)
AMP [cytosol]
Peroxisomal lipid metabolism (Drosophila melanogaster)
Alpha-oxidation of phytanate (Drosophila melanogaster)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Drosophila melanogaster)
AMP [cytosol]
Metabolism of steroids (Drosophila melanogaster)
Bile acid and bile salt metabolism (Drosophila melanogaster)
Recycling of bile acids and salts (Drosophila melanogaster)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
AMP [cytosol]
Synthesis of bile acids and bile salts (Drosophila melanogaster)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Drosophila melanogaster)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Drosophila melanogaster)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
AMP [cytosol]
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Drosophila melanogaster)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Drosophila melanogaster)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Drosophila melanogaster)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Drosophila melanogaster)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Drosophila melanogaster)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Drosophila melanogaster)
AMP [cytosol]
Nucleotide biosynthesis (Drosophila melanogaster)
Purine ribonucleoside monophosphate biosynthesis (Drosophila melanogaster)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Drosophila melanogaster)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Drosophila melanogaster)
AMP [cytosol]
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Drosophila melanogaster)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Drosophila melanogaster)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Drosophila melanogaster)
AMP [cytosol]
Metabolism of vitamins and cofactors (Drosophila melanogaster)
Metabolism of water-soluble vitamins and cofactors (Drosophila melanogaster)
Biotin transport and metabolism (Drosophila melanogaster)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Drosophila melanogaster)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Drosophila melanogaster)
AMP [cytosol]
HLCS biotinylates ACACB (Drosophila melanogaster)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Drosophila melanogaster)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Drosophila melanogaster)
Molybdenum ion transfer onto molybdopterin (Drosophila melanogaster)
AMP [cytosol]
Nicotinate metabolism (Drosophila melanogaster)
NADSYN1 hexamer amidates NAAD to NAD+ (Drosophila melanogaster)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Drosophila melanogaster)
2xTPK1:Mg2+ phosphorylates THMN (Drosophila melanogaster)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Drosophila melanogaster)
Coenzyme A biosynthesis (Drosophila melanogaster)
2xPPCS ligates PPanK with Cys (Drosophila melanogaster)
AMP [cytosol]
Metabolism of RNA (Drosophila melanogaster)
Deadenylation-dependent mRNA decay (Drosophila melanogaster)
mRNA decay by 3' to 5' exoribonuclease (Drosophila melanogaster)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Drosophila melanogaster)
AMP [cytosol]
Metabolism of proteins (Drosophila melanogaster)
Post-translational protein modification (Drosophila melanogaster)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Drosophila melanogaster)
Synthesis of diphthamide-EEF2 (Drosophila melanogaster)
DPH6 ligates ammonium to diphthine-EEF2 (Drosophila melanogaster)
AMP [cytosol]
Neddylation (Drosophila melanogaster)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Drosophila melanogaster)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Drosophila melanogaster)
AMP [cytosol]
Protein ubiquitination (Drosophila melanogaster)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Drosophila melanogaster)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Drosophila melanogaster)
AMP [cytosol]
Signal Transduction (Drosophila melanogaster)
Intracellular signaling by second messengers (Drosophila melanogaster)
DAG and IP3 signaling (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
Cam-PDE 1 activation (Drosophila melanogaster)
cAMP hydrolysis by Cam-PDE 1 (Drosophila melanogaster)
AMP [cytosol]
MTOR signalling (Drosophila melanogaster)
Energy dependent regulation of mTOR by LKB1-AMPK (Drosophila melanogaster)
AMPK phosphorylates Raptor in the mTORC1 complex (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Drosophila melanogaster)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
AMP [cytosol]
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (i) signalling events (Drosophila melanogaster)
Opioid Signalling (Drosophila melanogaster)
DARPP-32 events (Drosophila melanogaster)
PDE4A,C,D hydrolyse cAMP (Drosophila melanogaster)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Drosophila melanogaster)
AMP [cytosol]
G-protein mediated events (Drosophila melanogaster)
PLC beta mediated events (Drosophila melanogaster)
Ca-dependent events (Drosophila melanogaster)
CaM pathway (Drosophila melanogaster)
Calmodulin induced events (Drosophila melanogaster)
Cam-PDE 1 activation (Drosophila melanogaster)
cAMP hydrolysis by Cam-PDE 1 (Drosophila melanogaster)
AMP [cytosol]
G alpha (s) signalling events (Drosophila melanogaster)
PDE4A hydrolyses cAMP to AMP (Drosophila melanogaster)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Drosophila melanogaster)
AMP [cytosol]
Autophagy (Gallus gallus)
Macroautophagy (Gallus gallus)
AMPK (complex) phosphorylates ULK1 (complex) (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Gallus gallus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
ULK complex translocates to the ER (Gallus gallus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Gallus gallus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Gallus gallus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Gallus gallus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
Drug ADME (Gallus gallus)
Azathioprine ADME (Gallus gallus)
GMPS dimer transforms 6TXMP to 6TGMP (Gallus gallus)
AMP [cytosol]
Gene expression (Transcription) (Gallus gallus)
RNA Polymerase II Transcription (Gallus gallus)
Generic Transcription Pathway (Gallus gallus)
Transcriptional Regulation by TP53 (Gallus gallus)
TP53 Regulates Metabolic Genes (Gallus gallus)
SESN1,2,3 bind AMPK (Gallus gallus)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
Immune System (Gallus gallus)
Adaptive Immune System (Gallus gallus)
Class I MHC mediated antigen processing & presentation (Gallus gallus)
Antigen processing: Ubiquitination & Proteasome degradation (Gallus gallus)
E1 mediated ubiquitin activation (Gallus gallus)
AMP [cytosol]
Polyubiquitination of substrate (Gallus gallus)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
AMP [cytosol]
Cytokine Signaling in Immune system (Gallus gallus)
Interferon Signaling (Gallus gallus)
Antiviral mechanism by IFN-stimulated genes (Gallus gallus)
OAS antiviral response (Gallus gallus)
PDE12 cleaves 2'-5' oligoadenylates (Gallus gallus)
AMP [cytosol]
Metabolism (Gallus gallus)
Biological oxidations (Gallus gallus)
Phase I - Functionalization of compounds (Gallus gallus)
Ethanol oxidation (Gallus gallus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Gallus gallus)
AMP [cytosol]
Phase II - Conjugation of compounds (Gallus gallus)
Cytosolic sulfonation of small molecules (Gallus gallus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Gallus gallus)
AMP [cytosol]
Integration of energy metabolism (Gallus gallus)
Regulation of insulin secretion (Gallus gallus)
Free fatty acids regulate insulin secretion (Gallus gallus)
Intracellular metabolism of fatty acids regulates insulin secretion (Gallus gallus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Gallus gallus)
AMP [cytosol]
Metabolism of amino acids and derivatives (Gallus gallus)
Aspartate and asparagine metabolism (Gallus gallus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Gallus gallus)
AMP [cytosol]
Urea cycle (Gallus gallus)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Gallus gallus)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Gallus gallus)
Glucose metabolism (Gallus gallus)
Gluconeogenesis (Gallus gallus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Gallus gallus)
AMP [cytosol]
Glycolysis (Gallus gallus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Gallus gallus)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Gallus gallus)
AMP [cytosol]
Pentose phosphate pathway (Gallus gallus)
5-Phosphoribose 1-diphosphate biosynthesis (Gallus gallus)
PRPS dimers pyrophosphorylate R5P using ATP (Gallus gallus)
AMP [cytosol]
Metabolism of lipids (Gallus gallus)
Fatty acid metabolism (Gallus gallus)
Fatty acyl-CoA biosynthesis (Gallus gallus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Gallus gallus)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Gallus gallus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Gallus gallus)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Gallus gallus)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Gallus gallus)
AMP [cytosol]
Peroxisomal lipid metabolism (Gallus gallus)
Alpha-oxidation of phytanate (Gallus gallus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Gallus gallus)
AMP [cytosol]
Ketone body metabolism (Gallus gallus)
Synthesis of Ketone Bodies (Gallus gallus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Gallus gallus)
AMP [cytosol]
Metabolism of steroids (Gallus gallus)
Bile acid and bile salt metabolism (Gallus gallus)
Recycling of bile acids and salts (Gallus gallus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
AMP [cytosol]
Synthesis of bile acids and bile salts (Gallus gallus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Gallus gallus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Gallus gallus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
AMP [cytosol]
Metabolism of nucleotides (Gallus gallus)
Interconversion of nucleotide di- and triphosphates (Gallus gallus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Gallus gallus)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Gallus gallus)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Gallus gallus)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Gallus gallus)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Gallus gallus)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Gallus gallus)
AMP [cytosol]
Nucleotide biosynthesis (Gallus gallus)
Purine ribonucleoside monophosphate biosynthesis (Gallus gallus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Gallus gallus)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Gallus gallus)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Gallus gallus)
AMP [cytosol]
Nucleotide catabolism (Gallus gallus)
Purine catabolism (Gallus gallus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Gallus gallus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Gallus gallus)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Gallus gallus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Gallus gallus)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Gallus gallus)
AMP [cytosol]
Nucleotide salvage (Gallus gallus)
Purine salvage (Gallus gallus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Gallus gallus)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Gallus gallus)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Gallus gallus)
AMP [cytosol]
Metabolism of vitamins and cofactors (Gallus gallus)
Metabolism of water-soluble vitamins and cofactors (Gallus gallus)
Biotin transport and metabolism (Gallus gallus)
HLCS biotinylates 6x(PCCA:PCCB) (Gallus gallus)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Gallus gallus)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Gallus gallus)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Gallus gallus)
Molybdenum ion transfer onto molybdopterin (Gallus gallus)
AMP [cytosol]
Nicotinate metabolism (Gallus gallus)
NADSYN1 hexamer amidates NAAD to NAD+ (Gallus gallus)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Gallus gallus)
2xTPK1:Mg2+ phosphorylates THMN (Gallus gallus)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Gallus gallus)
Coenzyme A biosynthesis (Gallus gallus)
2xPPCS ligates PPanK with Cys (Gallus gallus)
AMP [cytosol]
Metabolism of RNA (Gallus gallus)
Deadenylation-dependent mRNA decay (Gallus gallus)
Deadenylation of mRNA (Gallus gallus)
CCR4-NOT complex deadenylates mRNA (Gallus gallus)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Gallus gallus)
AMP [cytosol]
PARN deadenylates mRNA (Gallus gallus)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Gallus gallus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Gallus gallus)
AMP [cytosol]
Metabolism of proteins (Gallus gallus)
Post-translational protein modification (Gallus gallus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Gallus gallus)
Synthesis of diphthamide-EEF2 (Gallus gallus)
DPH6 ligates ammonium to diphthine-EEF2 (Gallus gallus)
AMP [cytosol]
Neddylation (Gallus gallus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Gallus gallus)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Gallus gallus)
AMP [cytosol]
Protein ubiquitination (Gallus gallus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Gallus gallus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Gallus gallus)
AMP [cytosol]
Signal Transduction (Gallus gallus)
Intracellular signaling by second messengers (Gallus gallus)
DAG and IP3 signaling (Gallus gallus)
CaM pathway (Gallus gallus)
Calmodulin induced events (Gallus gallus)
Cam-PDE 1 activation (Gallus gallus)
cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)
AMP [cytosol]
MTOR signalling (Gallus gallus)
Energy dependent regulation of mTOR by LKB1-AMPK (Gallus gallus)
AMPK phosphorylates Raptor in the mTORC1 complex (Gallus gallus)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Gallus gallus)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Gallus gallus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
AMP [cytosol]
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (i) signalling events (Gallus gallus)
Opioid Signalling (Gallus gallus)
DARPP-32 events (Gallus gallus)
PDE4A,C,D hydrolyse cAMP (Gallus gallus)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Gallus gallus)
AMP [cytosol]
G-protein mediated events (Gallus gallus)
PLC beta mediated events (Gallus gallus)
Ca-dependent events (Gallus gallus)
CaM pathway (Gallus gallus)
Calmodulin induced events (Gallus gallus)
Cam-PDE 1 activation (Gallus gallus)
cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)
AMP [cytosol]
G alpha (s) signalling events (Gallus gallus)
PDE3A hydrolyses cAMP to AMP (Gallus gallus)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Gallus gallus)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Gallus gallus)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Gallus gallus)
Signaling by Insulin receptor (Gallus gallus)
Insulin receptor signalling cascade (Gallus gallus)
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PKB-mediated events (Gallus gallus)
PDE3B signalling (Gallus gallus)
p-S295-PDE3B hydrolyses cAMP to AMP (Gallus gallus)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Gallus gallus)
IGF1R signaling cascade (Gallus gallus)
IRS-related events triggered by IGF1R (Gallus gallus)
IRS-mediated signalling (Gallus gallus)
PI3K Cascade (Gallus gallus)
PKB-mediated events (Gallus gallus)
PDE3B signalling (Gallus gallus)
p-S295-PDE3B hydrolyses cAMP to AMP (Gallus gallus)
AMP [cytosol]
Autophagy (Homo sapiens)
Macroautophagy (Homo sapiens)
AMPK (complex) phosphorylates ULK1 (complex) (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Selective autophagy (Homo sapiens)
Lipophagy (Homo sapiens)
PRKAA2 phosphorylates PLINs (Homo sapiens)
AMPK-alpha2:AMPK-beta:AMPK-gamma:AMP [cytosol] (Homo sapiens)
AMPK gamma:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Homo sapiens)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
ULK complex translocates to the ER (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Homo sapiens)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to mechanical stimuli (Homo sapiens)
Response of endothelial cells to shear stress (Homo sapiens)
Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells (Homo sapiens)
PDE4D5 in p-S26-ANXA2:PP2A:PDE4D5:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP (Homo sapiens)
AMP [cytosol]
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
M-decay: degradation of maternal mRNAs by maternally stored factors (Homo sapiens)
CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP (Homo sapiens)
AMP [cytosol]
CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)
AMP [cytosol]
Disease (Homo sapiens)
Infectious disease (Homo sapiens)
Viral Infection Pathways (Homo sapiens)
Respiratory Syncytial Virus Infection Pathway (Homo sapiens)
RSV-host interactions (Homo sapiens)
ISGylation of BECN1 (Homo sapiens)
AMP [cytosol]
Drug ADME (Homo sapiens)
Abacavir ADME (Homo sapiens)
Abacavir metabolism (Homo sapiens)
abacavir + AMP => abacavir monophosphate + adenosine (Homo sapiens)
AMP [cytosol]
Azathioprine ADME (Homo sapiens)
GMPS dimer transforms 6TXMP to 6TGMP (Homo sapiens)
AMP [cytosol]
Gene expression (Transcription) (Homo sapiens)
RNA Polymerase II Transcription (Homo sapiens)
Generic Transcription Pathway (Homo sapiens)
Transcriptional Regulation by TP53 (Homo sapiens)
TP53 Regulates Metabolic Genes (Homo sapiens)
SESN1,2,3 bind AMPK (Homo sapiens)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Immune System (Homo sapiens)
Adaptive Immune System (Homo sapiens)
Class I MHC mediated antigen processing & presentation (Homo sapiens)
Antigen processing: Ubiquitination & Proteasome degradation (Homo sapiens)
E1 mediated ubiquitin activation (Homo sapiens)
AMP [cytosol]
Polyubiquitination of substrate (Homo sapiens)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
AMP [cytosol]
Cytokine Signaling in Immune system (Homo sapiens)
Interferon Signaling (Homo sapiens)
Antiviral mechanism by IFN-stimulated genes (Homo sapiens)
ISG15 antiviral mechanism (Homo sapiens)
Activation of ISG15 by UBA7 E1 ligase (Homo sapiens)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Homo sapiens)
AMP [cytosol]
ISGylation of IRF3 (Homo sapiens)
AMP [cytosol]
ISGylation of host protein filamin B (Homo sapiens)
AMP [cytosol]
ISGylation of host proteins (Homo sapiens)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Homo sapiens)
AMP [cytosol]
ISGylation of viral protein NS1 (Homo sapiens)
AMP [cytosol]
OAS antiviral response (Homo sapiens)
PDE12 cleaves 2'-5' oligoadenylates (Homo sapiens)
AMP [cytosol]
Viral 2',5'-PDE cleaves 2'-5' oligoadenylates (Homo sapiens)
AMP [cytosol]
PKR-mediated signaling (Homo sapiens)
ISGylation of PKR (Homo sapiens)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Homo sapiens)
ISGylation of DDX58 (RIG-I) (Homo sapiens)
AMP [cytosol]
Innate Immune System (Homo sapiens)
C-type lectin receptors (CLRs) (Homo sapiens)
CLEC7A (Dectin-1) signaling (Homo sapiens)
K63polyUb-TRAF6 ubiquitinates TAK1 (Homo sapiens)
AMP [cytosol]
TRAF6 oligomer autoubiquitinates (Homo sapiens)
AMP [cytosol]
Fc epsilon receptor (FCERI) signaling (Homo sapiens)
FCERI mediated NF-kB activation (Homo sapiens)
Auto-ubiquitination of TRAF6 (Homo sapiens)
AMP [cytosol]
Metabolism (Homo sapiens)
Biological oxidations (Homo sapiens)
Phase I - Functionalization of compounds (Homo sapiens)
Ethanol oxidation (Homo sapiens)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Homo sapiens)
AMP [cytosol]
Phase II - Conjugation of compounds (Homo sapiens)
Cytosolic sulfonation of small molecules (Homo sapiens)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Homo sapiens)
AMP [cytosol]
Integration of energy metabolism (Homo sapiens)
Regulation of insulin secretion (Homo sapiens)
Free fatty acids regulate insulin secretion (Homo sapiens)
Intracellular metabolism of fatty acids regulates insulin secretion (Homo sapiens)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Homo sapiens)
AMP [cytosol]
Metabolism of amino acids and derivatives (Homo sapiens)
Aspartate and asparagine metabolism (Homo sapiens)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Homo sapiens)
AMP [cytosol]
Selenoamino acid metabolism (Homo sapiens)
Selenocysteine synthesis (Homo sapiens)
SEPHS2 phosphorylates H2Se to form SELP (Homo sapiens)
AMP [cytosol]
tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer (Homo sapiens)
AMP [cytosol]
tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex (Homo sapiens)
AMP [cytosol]
Urea cycle (Homo sapiens)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Homo sapiens)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Homo sapiens)
Glucose metabolism (Homo sapiens)
Gluconeogenesis (Homo sapiens)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Homo sapiens)
AMP [cytosol]
Glycolysis (Homo sapiens)
ADPGK:Mg2+ phosphorylates Glc to G6P (Homo sapiens)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Homo sapiens)
AMP [cytosol]
Glycogen metabolism (Homo sapiens)
Glycogen breakdown (glycogenolysis) (Homo sapiens)
PYGB b dimer:AMP complex => PGYB dimer, b form + 2 AMP (Homo sapiens)
AMP [cytosol]
PYGB b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
PYGB dimer, b form + 2 AMP => PYGB b dimer:AMP complex (Homo sapiens)
AMP [cytosol]
PYGB b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Homo sapiens)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Homo sapiens)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
glycogen-glycogenin-1 + n orthophosphate => limit dextrin-glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] (Homo sapiens)
active PYGM and PYGB dimers [cytosol] (Homo sapiens)
PYGB b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
poly((1,4)-alpha-glycosyl) glycogenin-1 + n orthophosphate => glycogenin-1 + n D-glucose 1-phosphate [PYGM,PYGB] (Homo sapiens)
active PYGM and PYGB dimers [cytosol] (Homo sapiens)
PYGB b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Pentose phosphate pathway (Homo sapiens)
5-Phosphoribose 1-diphosphate biosynthesis (Homo sapiens)
PRPS dimers pyrophosphorylate R5P using ATP (Homo sapiens)
AMP [cytosol]
Metabolism of lipids (Homo sapiens)
Fatty acid metabolism (Homo sapiens)
Fatty acyl-CoA biosynthesis (Homo sapiens)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Homo sapiens)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Homo sapiens)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Homo sapiens)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Homo sapiens)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Homo sapiens)
AMP [cytosol]
Peroxisomal lipid metabolism (Homo sapiens)
Alpha-oxidation of phytanate (Homo sapiens)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Homo sapiens)
AMP [cytosol]
Ketone body metabolism (Homo sapiens)
Synthesis of Ketone Bodies (Homo sapiens)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Homo sapiens)
AMP [cytosol]
Metabolism of steroids (Homo sapiens)
Bile acid and bile salt metabolism (Homo sapiens)
Recycling of bile acids and salts (Homo sapiens)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
AMP [cytosol]
Synthesis of bile acids and bile salts (Homo sapiens)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Homo sapiens)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Homo sapiens)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
AMP [cytosol]
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Homo sapiens)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Homo sapiens)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Homo sapiens)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Homo sapiens)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Homo sapiens)
AMP [cytosol]
Nucleotide biosynthesis (Homo sapiens)
Purine ribonucleoside monophosphate biosynthesis (Homo sapiens)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Homo sapiens)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Homo sapiens)
AMP [cytosol]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Homo sapiens)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Homo sapiens)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Homo sapiens)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)
AMP [cytosol]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Homo sapiens)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Homo sapiens)
AMP [cytosol]
Metabolism of vitamins and cofactors (Homo sapiens)
Metabolism of water-soluble vitamins and cofactors (Homo sapiens)
Biotin transport and metabolism (Homo sapiens)
HLCS biotinylates 6x(PCCA:PCCB) (Homo sapiens)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Homo sapiens)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Homo sapiens)
AMP [cytosol]
HLCS biotinylates ACACB (Homo sapiens)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Homo sapiens)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Homo sapiens)
Molybdenum ion transfer onto molybdopterin (Homo sapiens)
AMP [cytosol]
Transfer of sulfur from MOCS3-S-S onto MOCS2A (Homo sapiens)
AMP [cytosol]
Nicotinate metabolism (Homo sapiens)
NADSYN1 hexamer amidates NAAD to NAD+ (Homo sapiens)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Homo sapiens)
2xTPK1:Mg2+ phosphorylates THMN (Homo sapiens)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Homo sapiens)
2xENPP1 hydrolyzes FAD to FMN (Homo sapiens)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Homo sapiens)
Coenzyme A biosynthesis (Homo sapiens)
2xPPCS ligates PPanK with Cys (Homo sapiens)
AMP [cytosol]
Metabolism of RNA (Homo sapiens)
Deadenylation-dependent mRNA decay (Homo sapiens)
Deadenylation of mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Homo sapiens)
AMP [cytosol]
PARN deadenylates mRNA (Homo sapiens)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Homo sapiens)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Homo sapiens)
AMP [cytosol]
mRNA decay by 5' to 3' exoribonuclease (Homo sapiens)
5' to 3' exoribonuclease hydrolyzes decapped mRNA (Homo sapiens)
AMP [cytosol]
Metabolism of proteins (Homo sapiens)
Post-translational protein modification (Homo sapiens)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Homo sapiens)
Synthesis of diphthamide-EEF2 (Homo sapiens)
DPH6 ligates ammonium to diphthine-EEF2 (Homo sapiens)
AMP [cytosol]
Neddylation (Homo sapiens)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Homo sapiens)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Homo sapiens)
AMP [cytosol]
Protein ubiquitination (Homo sapiens)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Homo sapiens)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Homo sapiens)
AMP [cytosol]
UBA6 conjugates ubiquitin to UBA6 in the cytosol (Homo sapiens)
AMP [cytosol]
Translation (Homo sapiens)
tRNA Aminoacylation (Homo sapiens)
Cytosolic tRNA aminoacylation (Homo sapiens)
alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)
AMP [cytosol]
Signal Transduction (Homo sapiens)
Intracellular signaling by second messengers (Homo sapiens)
DAG and IP3 signaling (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
Cam-PDE 1 activation (Homo sapiens)
cAMP hydrolysis by Cam-PDE 1 (Homo sapiens)
AMP [cytosol]
MTOR signalling (Homo sapiens)
Energy dependent regulation of mTOR by LKB1-AMPK (Homo sapiens)
AMPK phosphorylates Raptor in the mTORC1 complex (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Homo sapiens)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Homo sapiens)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (i) signalling events (Homo sapiens)
Opioid Signalling (Homo sapiens)
DARPP-32 events (Homo sapiens)
PDE4A,C,D hydrolyse cAMP (Homo sapiens)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Homo sapiens)
AMP [cytosol]
G-protein mediated events (Homo sapiens)
PLC beta mediated events (Homo sapiens)
Ca-dependent events (Homo sapiens)
CaM pathway (Homo sapiens)
Calmodulin induced events (Homo sapiens)
Cam-PDE 1 activation (Homo sapiens)
cAMP hydrolysis by Cam-PDE 1 (Homo sapiens)
AMP [cytosol]
G alpha (s) signalling events (Homo sapiens)
PDE3A hydrolyses cAMP to AMP (Homo sapiens)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Homo sapiens)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Homo sapiens)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Homo sapiens)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Homo sapiens)
Signaling by Insulin receptor (Homo sapiens)
Insulin receptor signalling cascade (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PKB-mediated events (Homo sapiens)
PDE3B signalling (Homo sapiens)
p-S295-PDE3B hydrolyses cAMP to AMP (Homo sapiens)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Homo sapiens)
IGF1R signaling cascade (Homo sapiens)
IRS-related events triggered by IGF1R (Homo sapiens)
IRS-mediated signalling (Homo sapiens)
PI3K Cascade (Homo sapiens)
PKB-mediated events (Homo sapiens)
PDE3B signalling (Homo sapiens)
p-S295-PDE3B hydrolyses cAMP to AMP (Homo sapiens)
AMP [cytosol]
Vesicle-mediated transport (Homo sapiens)
Membrane Trafficking (Homo sapiens)
Translocation of SLC2A4 (GLUT4) to the plasma membrane (Homo sapiens)
AMPK-alpha2 phosphorylates TBC1D1 (Homo sapiens)
AMPK-alpha2:AMPK-beta:AMPK-gamma:AMP [cytosol] (Homo sapiens)
AMPK gamma:AMP [cytosol] (Homo sapiens)
AMP [cytosol]
Autophagy (Mus musculus)
Macroautophagy (Mus musculus)
AMPK (complex) phosphorylates ULK1 (complex) (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Mus musculus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
ULK complex translocates to the ER (Mus musculus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Mus musculus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Mus musculus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Mus musculus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Drug ADME (Mus musculus)
Azathioprine ADME (Mus musculus)
GMPS dimer transforms 6TXMP to 6TGMP (Mus musculus)
AMP [cytosol]
Gene expression (Transcription) (Mus musculus)
RNA Polymerase II Transcription (Mus musculus)
Generic Transcription Pathway (Mus musculus)
Transcriptional Regulation by TP53 (Mus musculus)
TP53 Regulates Metabolic Genes (Mus musculus)
SESN1,2,3 bind AMPK (Mus musculus)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Immune System (Mus musculus)
Adaptive Immune System (Mus musculus)
Class I MHC mediated antigen processing & presentation (Mus musculus)
Antigen processing: Ubiquitination & Proteasome degradation (Mus musculus)
E1 mediated ubiquitin activation (Mus musculus)
AMP [cytosol]
Polyubiquitination of substrate (Mus musculus)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
AMP [cytosol]
Cytokine Signaling in Immune system (Mus musculus)
Interferon Signaling (Mus musculus)
Antiviral mechanism by IFN-stimulated genes (Mus musculus)
ISG15 antiviral mechanism (Mus musculus)
Activation of ISG15 by UBA7 E1 ligase (Mus musculus)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Mus musculus)
AMP [cytosol]
ISGylation of IRF3 (Mus musculus)
AMP [cytosol]
ISGylation of host protein filamin B (Mus musculus)
AMP [cytosol]
ISGylation of host proteins (Mus musculus)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Mus musculus)
AMP [cytosol]
OAS antiviral response (Mus musculus)
PDE12 cleaves 2'-5' oligoadenylates (Mus musculus)
AMP [cytosol]
PKR-mediated signaling (Mus musculus)
ISGylation of PKR (Mus musculus)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Mus musculus)
ISGylation of DDX58 (RIG-I) (Mus musculus)
AMP [cytosol]
Innate Immune System (Mus musculus)
C-type lectin receptors (CLRs) (Mus musculus)
CLEC7A (Dectin-1) signaling (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
AMP [cytosol]
TRAF6 oligomer autoubiquitinates (Mus musculus)
AMP [cytosol]
Fc epsilon receptor (FCERI) signaling (Mus musculus)
FCERI mediated NF-kB activation (Mus musculus)
Auto-ubiquitination of TRAF6 (Mus musculus)
AMP [cytosol]
Metabolism (Mus musculus)
Biological oxidations (Mus musculus)
Phase I - Functionalization of compounds (Mus musculus)
Ethanol oxidation (Mus musculus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Mus musculus)
AMP [cytosol]
Phase II - Conjugation of compounds (Mus musculus)
Cytosolic sulfonation of small molecules (Mus musculus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Mus musculus)
AMP [cytosol]
Integration of energy metabolism (Mus musculus)
Regulation of insulin secretion (Mus musculus)
Free fatty acids regulate insulin secretion (Mus musculus)
Intracellular metabolism of fatty acids regulates insulin secretion (Mus musculus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Mus musculus)
AMP [cytosol]
Metabolism of amino acids and derivatives (Mus musculus)
Aspartate and asparagine metabolism (Mus musculus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Mus musculus)
AMP [cytosol]
Selenoamino acid metabolism (Mus musculus)
Selenocysteine synthesis (Mus musculus)
SEPHS2 phosphorylates H2Se to form SELP (Mus musculus)
AMP [cytosol]
Urea cycle (Mus musculus)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Mus musculus)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Mus musculus)
Glucose metabolism (Mus musculus)
Gluconeogenesis (Mus musculus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Mus musculus)
AMP [cytosol]
Glycolysis (Mus musculus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Mus musculus)
AMP [cytosol]
Glycogen metabolism (Mus musculus)
Glycogen breakdown (glycogenolysis) (Mus musculus)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Mus musculus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Mus musculus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Pentose phosphate pathway (Mus musculus)
5-Phosphoribose 1-diphosphate biosynthesis (Mus musculus)
PRPS dimers pyrophosphorylate R5P using ATP (Mus musculus)
AMP [cytosol]
Metabolism of lipids (Mus musculus)
Fatty acid metabolism (Mus musculus)
Fatty acyl-CoA biosynthesis (Mus musculus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Mus musculus)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Mus musculus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Mus musculus)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Mus musculus)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Mus musculus)
AMP [cytosol]
Peroxisomal lipid metabolism (Mus musculus)
Alpha-oxidation of phytanate (Mus musculus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Mus musculus)
AMP [cytosol]
Ketone body metabolism (Mus musculus)
Synthesis of Ketone Bodies (Mus musculus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Mus musculus)
AMP [cytosol]
Metabolism of steroids (Mus musculus)
Bile acid and bile salt metabolism (Mus musculus)
Recycling of bile acids and salts (Mus musculus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
AMP [cytosol]
Synthesis of bile acids and bile salts (Mus musculus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Mus musculus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Mus musculus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
AMP [cytosol]
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Mus musculus)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Mus musculus)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Mus musculus)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Mus musculus)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Mus musculus)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Mus musculus)
AMP [cytosol]
Nucleotide biosynthesis (Mus musculus)
Purine ribonucleoside monophosphate biosynthesis (Mus musculus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Mus musculus)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Mus musculus)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Mus musculus)
AMP [cytosol]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Mus musculus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Mus musculus)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Mus musculus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Mus musculus)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Mus musculus)
AMP [cytosol]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Mus musculus)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Mus musculus)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Mus musculus)
AMP [cytosol]
Metabolism of vitamins and cofactors (Mus musculus)
Metabolism of water-soluble vitamins and cofactors (Mus musculus)
Biotin transport and metabolism (Mus musculus)
HLCS biotinylates 6x(PCCA:PCCB) (Mus musculus)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Mus musculus)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Mus musculus)
AMP [cytosol]
HLCS biotinylates ACACB (Mus musculus)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Mus musculus)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Mus musculus)
Molybdenum ion transfer onto molybdopterin (Mus musculus)
AMP [cytosol]
Nicotinate metabolism (Mus musculus)
NADSYN1 hexamer amidates NAAD to NAD+ (Mus musculus)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Mus musculus)
2xTPK1:Mg2+ phosphorylates THMN (Mus musculus)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Mus musculus)
2xENPP1 hydrolyzes FAD to FMN (Mus musculus)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Mus musculus)
Coenzyme A biosynthesis (Mus musculus)
2xPPCS ligates PPanK with Cys (Mus musculus)
AMP [cytosol]
Metabolism of RNA (Mus musculus)
Deadenylation-dependent mRNA decay (Mus musculus)
Deadenylation of mRNA (Mus musculus)
CCR4-NOT complex deadenylates mRNA (Mus musculus)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Mus musculus)
AMP [cytosol]
PARN deadenylates mRNA (Mus musculus)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Mus musculus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Mus musculus)
AMP [cytosol]
Metabolism of proteins (Mus musculus)
Post-translational protein modification (Mus musculus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Mus musculus)
Synthesis of diphthamide-EEF2 (Mus musculus)
DPH6 ligates ammonium to diphthine-EEF2 (Mus musculus)
AMP [cytosol]
Neddylation (Mus musculus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Mus musculus)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Mus musculus)
AMP [cytosol]
Protein ubiquitination (Mus musculus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Mus musculus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Mus musculus)
AMP [cytosol]
Signal Transduction (Mus musculus)
Intracellular signaling by second messengers (Mus musculus)
DAG and IP3 signaling (Mus musculus)
CaM pathway (Mus musculus)
Calmodulin induced events (Mus musculus)
Cam-PDE 1 activation (Mus musculus)
cAMP hydrolysis by Cam-PDE 1 (Mus musculus)
AMP [cytosol]
MTOR signalling (Mus musculus)
Energy dependent regulation of mTOR by LKB1-AMPK (Mus musculus)
AMPK phosphorylates Raptor in the mTORC1 complex (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Mus musculus)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Mus musculus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
AMP [cytosol]
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (i) signalling events (Mus musculus)
Opioid Signalling (Mus musculus)
DARPP-32 events (Mus musculus)
PDE4A,C,D hydrolyse cAMP (Mus musculus)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Mus musculus)
AMP [cytosol]
G-protein mediated events (Mus musculus)
PLC beta mediated events (Mus musculus)
Ca-dependent events (Mus musculus)
CaM pathway (Mus musculus)
Calmodulin induced events (Mus musculus)
Cam-PDE 1 activation (Mus musculus)
cAMP hydrolysis by Cam-PDE 1 (Mus musculus)
AMP [cytosol]
G alpha (s) signalling events (Mus musculus)
PDE3A hydrolyses cAMP to AMP (Mus musculus)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Mus musculus)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Mus musculus)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Mus musculus)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Mus musculus)
Signaling by Insulin receptor (Mus musculus)
Insulin receptor signalling cascade (Mus musculus)
IRS-mediated signalling (Mus musculus)
PI3K Cascade (Mus musculus)
PKB-mediated events (Mus musculus)
PDE3B signalling (Mus musculus)
p-S295-PDE3B hydrolyses cAMP to AMP (Mus musculus)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Mus musculus)
IGF1R signaling cascade (Mus musculus)
IRS-related events triggered by IGF1R (Mus musculus)
IRS-mediated signalling (Mus musculus)
PI3K Cascade (Mus musculus)
PKB-mediated events (Mus musculus)
PDE3B signalling (Mus musculus)
p-S295-PDE3B hydrolyses cAMP to AMP (Mus musculus)
AMP [cytosol]
Mycobacterium tuberculosis biological processes (Mycobacterium tuberculosis)
Dimycocersyl phthiocerol biosynthesis (Mycobacterium tuberculosis)
FadD26, FadD28 transfer LCFA adenylate ester to Pks5 (Mycobacterium tuberculosis)
AMP [cytosol]
Mycothiol metabolism (Mycobacterium tuberculosis)
Mycothiol biosynthesis (Mycobacterium tuberculosis)
glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol (Mycobacterium tuberculosis)
AMP [cytosol]
Sulfur compound metabolism (Mycobacterium tuberculosis)
Sulfur amino acid metabolism (Mycobacterium tuberculosis)
Cysteine synthesis from O-acetylserine (Mycobacterium tuberculosis)
sulfite results from reduction of APS (Mycobacterium tuberculosis)
AMP [cytosol]
Drug ADME (Plasmodium falciparum)
Azathioprine ADME (Plasmodium falciparum)
GMPS dimer transforms 6TXMP to 6TGMP (Plasmodium falciparum)
AMP [cytosol]
Immune System (Plasmodium falciparum)
Adaptive Immune System (Plasmodium falciparum)
Class I MHC mediated antigen processing & presentation (Plasmodium falciparum)
Antigen processing: Ubiquitination & Proteasome degradation (Plasmodium falciparum)
E1 mediated ubiquitin activation (Plasmodium falciparum)
AMP [cytosol]
Polyubiquitination of substrate (Plasmodium falciparum)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Plasmodium falciparum)
AMP [cytosol]
Cytokine Signaling in Immune system (Plasmodium falciparum)
Interferon Signaling (Plasmodium falciparum)
Antiviral mechanism by IFN-stimulated genes (Plasmodium falciparum)
ISG15 antiviral mechanism (Plasmodium falciparum)
Activation of ISG15 by UBA7 E1 ligase (Plasmodium falciparum)
AMP [cytosol]
Metabolism (Plasmodium falciparum)
Biological oxidations (Plasmodium falciparum)
Phase I - Functionalization of compounds (Plasmodium falciparum)
Ethanol oxidation (Plasmodium falciparum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Plasmodium falciparum)
AMP [cytosol]
Metabolism of amino acids and derivatives (Plasmodium falciparum)
Aspartate and asparagine metabolism (Plasmodium falciparum)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Plasmodium falciparum)
AMP [cytosol]
Selenoamino acid metabolism (Plasmodium falciparum)
Selenocysteine synthesis (Plasmodium falciparum)
SEPHS2 phosphorylates H2Se to form SELP (Plasmodium falciparum)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Plasmodium falciparum)
Pentose phosphate pathway (Plasmodium falciparum)
5-Phosphoribose 1-diphosphate biosynthesis (Plasmodium falciparum)
PRPS dimers pyrophosphorylate R5P using ATP (Plasmodium falciparum)
AMP [cytosol]
Metabolism of lipids (Plasmodium falciparum)
Fatty acid metabolism (Plasmodium falciparum)
Fatty acyl-CoA biosynthesis (Plasmodium falciparum)
Synthesis of very long-chain fatty acyl-CoAs (Plasmodium falciparum)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Plasmodium falciparum)
AMP [cytosol]
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Plasmodium falciparum)
(d)NMPs [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Plasmodium falciparum)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Plasmodium falciparum)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Plasmodium falciparum)
AMP [cytosol]
Nucleotide biosynthesis (Plasmodium falciparum)
Purine ribonucleoside monophosphate biosynthesis (Plasmodium falciparum)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)
AMP [cytosol]
Nucleotide salvage (Plasmodium falciparum)
Purine salvage (Plasmodium falciparum)
AMP + H2O => IMP + NH4+ (AMPD) (Plasmodium falciparum)
AMP [cytosol]
Metabolism of vitamins and cofactors (Plasmodium falciparum)
Metabolism of water-soluble vitamins and cofactors (Plasmodium falciparum)
Biotin transport and metabolism (Plasmodium falciparum)
HLCS biotinylates ACACA:Mn2+ (Plasmodium falciparum)
AMP [cytosol]
HLCS biotinylates ACACB (Plasmodium falciparum)
AMP [cytosol]
Nicotinate metabolism (Plasmodium falciparum)
NADSYN1 hexamer amidates NAAD to NAD+ (Plasmodium falciparum)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Plasmodium falciparum)
2xTPK1:Mg2+ phosphorylates THMN (Plasmodium falciparum)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Plasmodium falciparum)
Coenzyme A biosynthesis (Plasmodium falciparum)
2xPPCS ligates PPanK with Cys (Plasmodium falciparum)
AMP [cytosol]
Metabolism of proteins (Plasmodium falciparum)
Post-translational protein modification (Plasmodium falciparum)
Neddylation (Plasmodium falciparum)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Plasmodium falciparum)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Plasmodium falciparum)
AMP [cytosol]
Protein ubiquitination (Plasmodium falciparum)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Plasmodium falciparum)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Plasmodium falciparum)
AMP [cytosol]
Signal Transduction (Plasmodium falciparum)
Intracellular signaling by second messengers (Plasmodium falciparum)
DAG and IP3 signaling (Plasmodium falciparum)
CaM pathway (Plasmodium falciparum)
Calmodulin induced events (Plasmodium falciparum)
Cam-PDE 1 activation (Plasmodium falciparum)
cAMP hydrolysis by Cam-PDE 1 (Plasmodium falciparum)
AMP [cytosol]
Signaling by GPCR (Plasmodium falciparum)
GPCR downstream signalling (Plasmodium falciparum)
G alpha (i) signalling events (Plasmodium falciparum)
Opioid Signalling (Plasmodium falciparum)
DARPP-32 events (Plasmodium falciparum)
PDE4A,C,D hydrolyse cAMP (Plasmodium falciparum)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Plasmodium falciparum)
AMP [cytosol]
G-protein mediated events (Plasmodium falciparum)
PLC beta mediated events (Plasmodium falciparum)
Ca-dependent events (Plasmodium falciparum)
CaM pathway (Plasmodium falciparum)
Calmodulin induced events (Plasmodium falciparum)
Cam-PDE 1 activation (Plasmodium falciparum)
cAMP hydrolysis by Cam-PDE 1 (Plasmodium falciparum)
AMP [cytosol]
G alpha (s) signalling events (Plasmodium falciparum)
PDE3A hydrolyses cAMP to AMP (Plasmodium falciparum)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Plasmodium falciparum)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Plasmodium falciparum)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Plasmodium falciparum)
Signaling by Insulin receptor (Plasmodium falciparum)
Insulin receptor signalling cascade (Plasmodium falciparum)
IRS-mediated signalling (Plasmodium falciparum)
PI3K Cascade (Plasmodium falciparum)
PKB-mediated events (Plasmodium falciparum)
PDE3B signalling (Plasmodium falciparum)
p-S295-PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Plasmodium falciparum)
IGF1R signaling cascade (Plasmodium falciparum)
IRS-related events triggered by IGF1R (Plasmodium falciparum)
IRS-mediated signalling (Plasmodium falciparum)
PI3K Cascade (Plasmodium falciparum)
PKB-mediated events (Plasmodium falciparum)
PDE3B signalling (Plasmodium falciparum)
p-S295-PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)
AMP [cytosol]
Autophagy (Rattus norvegicus)
Macroautophagy (Rattus norvegicus)
AMPK (complex) phosphorylates ULK1 (complex) (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
ULK complex translocates to the ER (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Rattus norvegicus)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Drug ADME (Rattus norvegicus)
Azathioprine ADME (Rattus norvegicus)
GMPS dimer transforms 6TXMP to 6TGMP (Rattus norvegicus)
AMP [cytosol]
Gene expression (Transcription) (Rattus norvegicus)
RNA Polymerase II Transcription (Rattus norvegicus)
Generic Transcription Pathway (Rattus norvegicus)
Transcriptional Regulation by TP53 (Rattus norvegicus)
TP53 Regulates Metabolic Genes (Rattus norvegicus)
SESN1,2,3 bind AMPK (Rattus norvegicus)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Immune System (Rattus norvegicus)
Adaptive Immune System (Rattus norvegicus)
Class I MHC mediated antigen processing & presentation (Rattus norvegicus)
Antigen processing: Ubiquitination & Proteasome degradation (Rattus norvegicus)
E1 mediated ubiquitin activation (Rattus norvegicus)
AMP [cytosol]
Polyubiquitination of substrate (Rattus norvegicus)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
AMP [cytosol]
Cytokine Signaling in Immune system (Rattus norvegicus)
Interferon Signaling (Rattus norvegicus)
Antiviral mechanism by IFN-stimulated genes (Rattus norvegicus)
ISG15 antiviral mechanism (Rattus norvegicus)
Activation of ISG15 by UBA7 E1 ligase (Rattus norvegicus)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Rattus norvegicus)
AMP [cytosol]
ISGylation of IRF3 (Rattus norvegicus)
AMP [cytosol]
ISGylation of host protein filamin B (Rattus norvegicus)
AMP [cytosol]
ISGylation of host proteins (Rattus norvegicus)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Rattus norvegicus)
AMP [cytosol]
OAS antiviral response (Rattus norvegicus)
PDE12 cleaves 2'-5' oligoadenylates (Rattus norvegicus)
AMP [cytosol]
PKR-mediated signaling (Rattus norvegicus)
ISGylation of PKR (Rattus norvegicus)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Rattus norvegicus)
ISGylation of DDX58 (RIG-I) (Rattus norvegicus)
AMP [cytosol]
Metabolism (Rattus norvegicus)
Biological oxidations (Rattus norvegicus)
Phase I - Functionalization of compounds (Rattus norvegicus)
Ethanol oxidation (Rattus norvegicus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Rattus norvegicus)
AMP [cytosol]
Phase II - Conjugation of compounds (Rattus norvegicus)
Cytosolic sulfonation of small molecules (Rattus norvegicus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Rattus norvegicus)
AMP [cytosol]
Integration of energy metabolism (Rattus norvegicus)
Regulation of insulin secretion (Rattus norvegicus)
Free fatty acids regulate insulin secretion (Rattus norvegicus)
Intracellular metabolism of fatty acids regulates insulin secretion (Rattus norvegicus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Rattus norvegicus)
AMP [cytosol]
Metabolism of amino acids and derivatives (Rattus norvegicus)
Aspartate and asparagine metabolism (Rattus norvegicus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Rattus norvegicus)
AMP [cytosol]
Selenoamino acid metabolism (Rattus norvegicus)
Selenocysteine synthesis (Rattus norvegicus)
SEPHS2 phosphorylates H2Se to form SELP (Rattus norvegicus)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Rattus norvegicus)
Glucose metabolism (Rattus norvegicus)
Gluconeogenesis (Rattus norvegicus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Rattus norvegicus)
AMP [cytosol]
Glycolysis (Rattus norvegicus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Rattus norvegicus)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Rattus norvegicus)
AMP [cytosol]
Glycogen metabolism (Rattus norvegicus)
Glycogen breakdown (glycogenolysis) (Rattus norvegicus)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Rattus norvegicus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Rattus norvegicus)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Pentose phosphate pathway (Rattus norvegicus)
5-Phosphoribose 1-diphosphate biosynthesis (Rattus norvegicus)
PRPS dimers pyrophosphorylate R5P using ATP (Rattus norvegicus)
AMP [cytosol]
Metabolism of lipids (Rattus norvegicus)
Fatty acid metabolism (Rattus norvegicus)
Fatty acyl-CoA biosynthesis (Rattus norvegicus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Rattus norvegicus)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Rattus norvegicus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Rattus norvegicus)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Rattus norvegicus)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Rattus norvegicus)
AMP [cytosol]
Ketone body metabolism (Rattus norvegicus)
Synthesis of Ketone Bodies (Rattus norvegicus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Rattus norvegicus)
AMP [cytosol]
Metabolism of steroids (Rattus norvegicus)
Bile acid and bile salt metabolism (Rattus norvegicus)
Recycling of bile acids and salts (Rattus norvegicus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
AMP [cytosol]
Synthesis of bile acids and bile salts (Rattus norvegicus)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Rattus norvegicus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Rattus norvegicus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
AMP [cytosol]
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Rattus norvegicus)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Rattus norvegicus)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Rattus norvegicus)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Rattus norvegicus)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Rattus norvegicus)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Rattus norvegicus)
AMP [cytosol]
Nucleotide biosynthesis (Rattus norvegicus)
Purine ribonucleoside monophosphate biosynthesis (Rattus norvegicus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Rattus norvegicus)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Rattus norvegicus)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Rattus norvegicus)
AMP [cytosol]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Rattus norvegicus)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Rattus norvegicus)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Rattus norvegicus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)
AMP [cytosol]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Rattus norvegicus)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Rattus norvegicus)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Rattus norvegicus)
AMP [cytosol]
Metabolism of vitamins and cofactors (Rattus norvegicus)
Metabolism of water-soluble vitamins and cofactors (Rattus norvegicus)
Biotin transport and metabolism (Rattus norvegicus)
HLCS biotinylates 6x(PCCA:PCCB) (Rattus norvegicus)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Rattus norvegicus)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Rattus norvegicus)
AMP [cytosol]
HLCS biotinylates ACACB (Rattus norvegicus)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Rattus norvegicus)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Rattus norvegicus)
Molybdenum ion transfer onto molybdopterin (Rattus norvegicus)
AMP [cytosol]
Nicotinate metabolism (Rattus norvegicus)
NADSYN1 hexamer amidates NAAD to NAD+ (Rattus norvegicus)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Rattus norvegicus)
2xTPK1:Mg2+ phosphorylates THMN (Rattus norvegicus)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Rattus norvegicus)
2xENPP1 hydrolyzes FAD to FMN (Rattus norvegicus)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Rattus norvegicus)
Coenzyme A biosynthesis (Rattus norvegicus)
2xPPCS ligates PPanK with Cys (Rattus norvegicus)
AMP [cytosol]
Metabolism of RNA (Rattus norvegicus)
Deadenylation-dependent mRNA decay (Rattus norvegicus)
Deadenylation of mRNA (Rattus norvegicus)
PAN2-PAN3 complex partially deadenylates mRNA (Rattus norvegicus)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Rattus norvegicus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Rattus norvegicus)
AMP [cytosol]
Metabolism of proteins (Rattus norvegicus)
Post-translational protein modification (Rattus norvegicus)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Rattus norvegicus)
Synthesis of diphthamide-EEF2 (Rattus norvegicus)
DPH6 ligates ammonium to diphthine-EEF2 (Rattus norvegicus)
AMP [cytosol]
Neddylation (Rattus norvegicus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Rattus norvegicus)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Rattus norvegicus)
AMP [cytosol]
Protein ubiquitination (Rattus norvegicus)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Rattus norvegicus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Rattus norvegicus)
AMP [cytosol]
Signal Transduction (Rattus norvegicus)
Intracellular signaling by second messengers (Rattus norvegicus)
DAG and IP3 signaling (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
Cam-PDE 1 activation (Rattus norvegicus)
cAMP hydrolysis by Cam-PDE 1 (Rattus norvegicus)
AMP [cytosol]
MTOR signalling (Rattus norvegicus)
Energy dependent regulation of mTOR by LKB1-AMPK (Rattus norvegicus)
AMPK phosphorylates Raptor in the mTORC1 complex (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Rattus norvegicus)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Rattus norvegicus)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
AMP [cytosol]
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (i) signalling events (Rattus norvegicus)
Opioid Signalling (Rattus norvegicus)
DARPP-32 events (Rattus norvegicus)
PDE4A,C,D hydrolyse cAMP (Rattus norvegicus)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Rattus norvegicus)
AMP [cytosol]
G-protein mediated events (Rattus norvegicus)
PLC beta mediated events (Rattus norvegicus)
Ca-dependent events (Rattus norvegicus)
CaM pathway (Rattus norvegicus)
Calmodulin induced events (Rattus norvegicus)
Cam-PDE 1 activation (Rattus norvegicus)
cAMP hydrolysis by Cam-PDE 1 (Rattus norvegicus)
AMP [cytosol]
G alpha (s) signalling events (Rattus norvegicus)
PDE3A hydrolyses cAMP to AMP (Rattus norvegicus)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Rattus norvegicus)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Rattus norvegicus)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Rattus norvegicus)
Signaling by Insulin receptor (Rattus norvegicus)
Insulin receptor signalling cascade (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PKB-mediated events (Rattus norvegicus)
PDE3B signalling (Rattus norvegicus)
p-S295-PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Rattus norvegicus)
IGF1R signaling cascade (Rattus norvegicus)
IRS-related events triggered by IGF1R (Rattus norvegicus)
IRS-mediated signalling (Rattus norvegicus)
PI3K Cascade (Rattus norvegicus)
PKB-mediated events (Rattus norvegicus)
PDE3B signalling (Rattus norvegicus)
p-S295-PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)
AMP [cytosol]
Autophagy (Saccharomyces cerevisiae)
Macroautophagy (Saccharomyces cerevisiae)
AMPK (complex) phosphorylates ULK1 (complex) (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
ULK complex translocates to the ER (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
Drug ADME (Saccharomyces cerevisiae)
Azathioprine ADME (Saccharomyces cerevisiae)
GMPS dimer transforms 6TXMP to 6TGMP (Saccharomyces cerevisiae)
AMP [cytosol]
Immune System (Saccharomyces cerevisiae)
Adaptive Immune System (Saccharomyces cerevisiae)
Class I MHC mediated antigen processing & presentation (Saccharomyces cerevisiae)
Antigen processing: Ubiquitination & Proteasome degradation (Saccharomyces cerevisiae)
E1 mediated ubiquitin activation (Saccharomyces cerevisiae)
AMP [cytosol]
Polyubiquitination of substrate (Saccharomyces cerevisiae)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism (Saccharomyces cerevisiae)
Biological oxidations (Saccharomyces cerevisiae)
Phase I - Functionalization of compounds (Saccharomyces cerevisiae)
Ethanol oxidation (Saccharomyces cerevisiae)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Saccharomyces cerevisiae)
AMP [cytosol]
Integration of energy metabolism (Saccharomyces cerevisiae)
Regulation of insulin secretion (Saccharomyces cerevisiae)
Free fatty acids regulate insulin secretion (Saccharomyces cerevisiae)
Intracellular metabolism of fatty acids regulates insulin secretion (Saccharomyces cerevisiae)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Aspartate and asparagine metabolism (Saccharomyces cerevisiae)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Saccharomyces cerevisiae)
Glucose metabolism (Saccharomyces cerevisiae)
Gluconeogenesis (Saccharomyces cerevisiae)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Saccharomyces cerevisiae)
AMP [cytosol]
Glycolysis (Saccharomyces cerevisiae)
PFK tetramer phosphorylates Fru(6)P (Saccharomyces cerevisiae)
AMP [cytosol]
Glycogen metabolism (Saccharomyces cerevisiae)
Glycogen breakdown (glycogenolysis) (Saccharomyces cerevisiae)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Saccharomyces cerevisiae)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Saccharomyces cerevisiae)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
Pentose phosphate pathway (Saccharomyces cerevisiae)
5-Phosphoribose 1-diphosphate biosynthesis (Saccharomyces cerevisiae)
PRPS dimers pyrophosphorylate R5P using ATP (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of lipids (Saccharomyces cerevisiae)
Fatty acid metabolism (Saccharomyces cerevisiae)
Fatty acyl-CoA biosynthesis (Saccharomyces cerevisiae)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Saccharomyces cerevisiae)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Saccharomyces cerevisiae)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Saccharomyces cerevisiae)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of steroids (Saccharomyces cerevisiae)
Bile acid and bile salt metabolism (Saccharomyces cerevisiae)
Recycling of bile acids and salts (Saccharomyces cerevisiae)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
AMP [cytosol]
Synthesis of bile acids and bile salts (Saccharomyces cerevisiae)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Saccharomyces cerevisiae)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Saccharomyces cerevisiae)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
ADP + ADP <=> AMP + ATP [AK2] (Saccharomyces cerevisiae)
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Saccharomyces cerevisiae)
AMP [cytosol]
Nucleotide biosynthesis (Saccharomyces cerevisiae)
Purine ribonucleoside monophosphate biosynthesis (Saccharomyces cerevisiae)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Saccharomyces cerevisiae)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Saccharomyces cerevisiae)
AMP [cytosol]
Nucleotide catabolism (Saccharomyces cerevisiae)
Purine catabolism (Saccharomyces cerevisiae)
Phosphate bond hydrolysis by NUDT proteins (Saccharomyces cerevisiae)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Saccharomyces cerevisiae)
AMP [cytosol]
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Saccharomyces cerevisiae)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Saccharomyces cerevisiae)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of vitamins and cofactors (Saccharomyces cerevisiae)
Metabolism of water-soluble vitamins and cofactors (Saccharomyces cerevisiae)
Biotin transport and metabolism (Saccharomyces cerevisiae)
HLCS biotinylates ACACA:Mn2+ (Saccharomyces cerevisiae)
AMP [cytosol]
HLCS biotinylates ACACB (Saccharomyces cerevisiae)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Saccharomyces cerevisiae)
AMP [cytosol]
Nicotinate metabolism (Saccharomyces cerevisiae)
NADSYN1 hexamer amidates NAAD to NAD+ (Saccharomyces cerevisiae)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Saccharomyces cerevisiae)
2xTPK1:Mg2+ phosphorylates THMN (Saccharomyces cerevisiae)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Saccharomyces cerevisiae)
2xENPP1 hydrolyzes FAD to FMN (Saccharomyces cerevisiae)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Saccharomyces cerevisiae)
Coenzyme A biosynthesis (Saccharomyces cerevisiae)
2xPPCS ligates PPanK with Cys (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of RNA (Saccharomyces cerevisiae)
Deadenylation-dependent mRNA decay (Saccharomyces cerevisiae)
Deadenylation of mRNA (Saccharomyces cerevisiae)
PAN2-PAN3 complex partially deadenylates mRNA (Saccharomyces cerevisiae)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Saccharomyces cerevisiae)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Saccharomyces cerevisiae)
AMP [cytosol]
Metabolism of proteins (Saccharomyces cerevisiae)
Post-translational protein modification (Saccharomyces cerevisiae)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Saccharomyces cerevisiae)
Synthesis of diphthamide-EEF2 (Saccharomyces cerevisiae)
DPH6 ligates ammonium to diphthine-EEF2 (Saccharomyces cerevisiae)
AMP [cytosol]
Neddylation (Saccharomyces cerevisiae)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Saccharomyces cerevisiae)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Saccharomyces cerevisiae)
AMP [cytosol]
Protein ubiquitination (Saccharomyces cerevisiae)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Saccharomyces cerevisiae)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Saccharomyces cerevisiae)
AMP [cytosol]
Signal Transduction (Saccharomyces cerevisiae)
MTOR signalling (Saccharomyces cerevisiae)
Energy dependent regulation of mTOR by LKB1-AMPK (Saccharomyces cerevisiae)
Phosphorylated AMPK binds AMP (Saccharomyces cerevisiae)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
AMP [cytosol]
Autophagy (Schizosaccharomyces pombe)
Macroautophagy (Schizosaccharomyces pombe)
AMPK (complex) phosphorylates ULK1 (complex) (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
ULK complex translocates to the ER (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
Drug ADME (Schizosaccharomyces pombe)
Azathioprine ADME (Schizosaccharomyces pombe)
GMPS dimer transforms 6TXMP to 6TGMP (Schizosaccharomyces pombe)
AMP [cytosol]
Gene expression (Transcription) (Schizosaccharomyces pombe)
RNA Polymerase II Transcription (Schizosaccharomyces pombe)
Generic Transcription Pathway (Schizosaccharomyces pombe)
Transcriptional Regulation by TP53 (Schizosaccharomyces pombe)
TP53 Regulates Metabolic Genes (Schizosaccharomyces pombe)
p-AMPK phosphorylates TSC1:TSC2 (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
Immune System (Schizosaccharomyces pombe)
Adaptive Immune System (Schizosaccharomyces pombe)
Class I MHC mediated antigen processing & presentation (Schizosaccharomyces pombe)
Antigen processing: Ubiquitination & Proteasome degradation (Schizosaccharomyces pombe)
E1 mediated ubiquitin activation (Schizosaccharomyces pombe)
AMP [cytosol]
Polyubiquitination of substrate (Schizosaccharomyces pombe)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism (Schizosaccharomyces pombe)
Biological oxidations (Schizosaccharomyces pombe)
Phase I - Functionalization of compounds (Schizosaccharomyces pombe)
Ethanol oxidation (Schizosaccharomyces pombe)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Schizosaccharomyces pombe)
AMP [cytosol]
Integration of energy metabolism (Schizosaccharomyces pombe)
Regulation of insulin secretion (Schizosaccharomyces pombe)
Free fatty acids regulate insulin secretion (Schizosaccharomyces pombe)
Intracellular metabolism of fatty acids regulates insulin secretion (Schizosaccharomyces pombe)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Aspartate and asparagine metabolism (Schizosaccharomyces pombe)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Schizosaccharomyces pombe)
Glucose metabolism (Schizosaccharomyces pombe)
Gluconeogenesis (Schizosaccharomyces pombe)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Schizosaccharomyces pombe)
AMP [cytosol]
Glycolysis (Schizosaccharomyces pombe)
PFK tetramer phosphorylates Fru(6)P (Schizosaccharomyces pombe)
AMP [cytosol]
Pentose phosphate pathway (Schizosaccharomyces pombe)
5-Phosphoribose 1-diphosphate biosynthesis (Schizosaccharomyces pombe)
PRPS dimers pyrophosphorylate R5P using ATP (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of lipids (Schizosaccharomyces pombe)
Fatty acid metabolism (Schizosaccharomyces pombe)
Fatty acyl-CoA biosynthesis (Schizosaccharomyces pombe)
Synthesis of very long-chain fatty acyl-CoAs (Schizosaccharomyces pombe)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Schizosaccharomyces pombe)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Schizosaccharomyces pombe)
AMP [cytosol]
Nucleotide biosynthesis (Schizosaccharomyces pombe)
Purine ribonucleoside monophosphate biosynthesis (Schizosaccharomyces pombe)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Schizosaccharomyces pombe)
AMP [cytosol]
Nucleotide catabolism (Schizosaccharomyces pombe)
Purine catabolism (Schizosaccharomyces pombe)
Phosphate bond hydrolysis by NUDT proteins (Schizosaccharomyces pombe)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Schizosaccharomyces pombe)
AMP [cytosol]
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Schizosaccharomyces pombe)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of vitamins and cofactors (Schizosaccharomyces pombe)
Metabolism of water-soluble vitamins and cofactors (Schizosaccharomyces pombe)
Biotin transport and metabolism (Schizosaccharomyces pombe)
HLCS biotinylates ACACA:Mn2+ (Schizosaccharomyces pombe)
AMP [cytosol]
HLCS biotinylates ACACB (Schizosaccharomyces pombe)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Schizosaccharomyces pombe)
AMP [cytosol]
Nicotinate metabolism (Schizosaccharomyces pombe)
NADSYN1 hexamer amidates NAAD to NAD+ (Schizosaccharomyces pombe)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Schizosaccharomyces pombe)
2xTPK1:Mg2+ phosphorylates THMN (Schizosaccharomyces pombe)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Schizosaccharomyces pombe)
2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Schizosaccharomyces pombe)
Coenzyme A biosynthesis (Schizosaccharomyces pombe)
2xPPCS ligates PPanK with Cys (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of RNA (Schizosaccharomyces pombe)
Deadenylation-dependent mRNA decay (Schizosaccharomyces pombe)
mRNA decay by 3' to 5' exoribonuclease (Schizosaccharomyces pombe)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Schizosaccharomyces pombe)
AMP [cytosol]
Metabolism of proteins (Schizosaccharomyces pombe)
Post-translational protein modification (Schizosaccharomyces pombe)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Schizosaccharomyces pombe)
Synthesis of diphthamide-EEF2 (Schizosaccharomyces pombe)
DPH6 ligates ammonium to diphthine-EEF2 (Schizosaccharomyces pombe)
AMP [cytosol]
Neddylation (Schizosaccharomyces pombe)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)
AMP [cytosol]
NEDD8-UBA3:NAE1 binds a second NEDD8 (Schizosaccharomyces pombe)
AMP [cytosol]
Protein ubiquitination (Schizosaccharomyces pombe)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Schizosaccharomyces pombe)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Schizosaccharomyces pombe)
AMP [cytosol]
Signal Transduction (Schizosaccharomyces pombe)
MTOR signalling (Schizosaccharomyces pombe)
Energy dependent regulation of mTOR by LKB1-AMPK (Schizosaccharomyces pombe)
Phosphorylated AMPK binds AMP (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
AMP [cytosol]
Autophagy (Sus scrofa)
Macroautophagy (Sus scrofa)
AMPK (complex) phosphorylates ULK1 (complex) (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Sus scrofa)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
ULK complex translocates to the ER (Sus scrofa)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Sus scrofa)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Sus scrofa)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Sus scrofa)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK:AMP binds the ULK complex (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK:AMP phosphorylates Raptor in the MTORC1 complex (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Drug ADME (Sus scrofa)
Azathioprine ADME (Sus scrofa)
GMPS dimer transforms 6TXMP to 6TGMP (Sus scrofa)
AMP [cytosol]
Gene expression (Transcription) (Sus scrofa)
RNA Polymerase II Transcription (Sus scrofa)
Generic Transcription Pathway (Sus scrofa)
Transcriptional Regulation by TP53 (Sus scrofa)
TP53 Regulates Metabolic Genes (Sus scrofa)
SESN1,2,3 bind AMPK (Sus scrofa)
SESN1,2,3:p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Immune System (Sus scrofa)
Adaptive Immune System (Sus scrofa)
Class I MHC mediated antigen processing & presentation (Sus scrofa)
Antigen processing: Ubiquitination & Proteasome degradation (Sus scrofa)
E1 mediated ubiquitin activation (Sus scrofa)
AMP [cytosol]
Polyubiquitination of substrate (Sus scrofa)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)
AMP [cytosol]
Cytokine Signaling in Immune system (Sus scrofa)
Interferon Signaling (Sus scrofa)
Antiviral mechanism by IFN-stimulated genes (Sus scrofa)
ISG15 antiviral mechanism (Sus scrofa)
Activation of ISG15 by UBA7 E1 ligase (Sus scrofa)
AMP [cytosol]
ISGylation of E2 conjugating enzymes (Sus scrofa)
AMP [cytosol]
ISGylation of IRF3 (Sus scrofa)
AMP [cytosol]
ISGylation of host protein filamin B (Sus scrofa)
AMP [cytosol]
ISGylation of host proteins (Sus scrofa)
AMP [cytosol]
ISGylation of protein phosphatase 1 beta (PP2CB) (Sus scrofa)
AMP [cytosol]
OAS antiviral response (Sus scrofa)
PDE12 cleaves 2'-5' oligoadenylates (Sus scrofa)
AMP [cytosol]
PKR-mediated signaling (Sus scrofa)
ISGylation of PKR (Sus scrofa)
AMP [cytosol]
Modulation of host responses by IFN-stimulated genes (Sus scrofa)
ISGylation of DDX58 (RIG-I) (Sus scrofa)
AMP [cytosol]
Innate Immune System (Sus scrofa)
C-type lectin receptors (CLRs) (Sus scrofa)
CLEC7A (Dectin-1) signaling (Sus scrofa)
K63polyUb-TRAF6 ubiquitinates TAK1 (Sus scrofa)
AMP [cytosol]
TRAF6 oligomer autoubiquitinates (Sus scrofa)
AMP [cytosol]
Fc epsilon receptor (FCERI) signaling (Sus scrofa)
FCERI mediated NF-kB activation (Sus scrofa)
Auto-ubiquitination of TRAF6 (Sus scrofa)
AMP [cytosol]
Metabolism (Sus scrofa)
Biological oxidations (Sus scrofa)
Phase I - Functionalization of compounds (Sus scrofa)
Ethanol oxidation (Sus scrofa)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Sus scrofa)
AMP [cytosol]
Phase II - Conjugation of compounds (Sus scrofa)
Cytosolic sulfonation of small molecules (Sus scrofa)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Sus scrofa)
AMP [cytosol]
Integration of energy metabolism (Sus scrofa)
Regulation of insulin secretion (Sus scrofa)
Free fatty acids regulate insulin secretion (Sus scrofa)
Intracellular metabolism of fatty acids regulates insulin secretion (Sus scrofa)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Sus scrofa)
AMP [cytosol]
Metabolism of amino acids and derivatives (Sus scrofa)
Aspartate and asparagine metabolism (Sus scrofa)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Sus scrofa)
AMP [cytosol]
Selenoamino acid metabolism (Sus scrofa)
Selenocysteine synthesis (Sus scrofa)
SEPHS2 phosphorylates H2Se to form SELP (Sus scrofa)
AMP [cytosol]
Urea cycle (Sus scrofa)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Sus scrofa)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Sus scrofa)
Glucose metabolism (Sus scrofa)
Gluconeogenesis (Sus scrofa)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Sus scrofa)
AMP [cytosol]
Glycolysis (Sus scrofa)
ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)
AMP [cytosol]
PFK tetramer phosphorylates Fru(6)P (Sus scrofa)
AMP [cytosol]
Glycogen metabolism (Sus scrofa)
Glycogen breakdown (glycogenolysis) (Sus scrofa)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Sus scrofa)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Sus scrofa)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Pentose phosphate pathway (Sus scrofa)
5-Phosphoribose 1-diphosphate biosynthesis (Sus scrofa)
PRPS dimers pyrophosphorylate R5P using ATP (Sus scrofa)
AMP [cytosol]
Metabolism of lipids (Sus scrofa)
Fatty acid metabolism (Sus scrofa)
Fatty acyl-CoA biosynthesis (Sus scrofa)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Sus scrofa)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Sus scrofa)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Sus scrofa)
AMP [cytosol]
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Sus scrofa)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Sus scrofa)
AMP [cytosol]
Peroxisomal lipid metabolism (Sus scrofa)
Alpha-oxidation of phytanate (Sus scrofa)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Sus scrofa)
AMP [cytosol]
Ketone body metabolism (Sus scrofa)
Synthesis of Ketone Bodies (Sus scrofa)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Sus scrofa)
AMP [cytosol]
Metabolism of steroids (Sus scrofa)
Bile acid and bile salt metabolism (Sus scrofa)
Recycling of bile acids and salts (Sus scrofa)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
AMP [cytosol]
Synthesis of bile acids and bile salts (Sus scrofa)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Sus scrofa)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Sus scrofa)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
AMP [cytosol]
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
(d)ADP + ADP <=> (d)AMP + ATP (AK1) (Sus scrofa)
(d)AMP [cytosol]
AMP [cytosol]
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Sus scrofa)
(d)NMPs [cytosol]
AMP [cytosol]
(d)AMP + ATP <=> (d)ADP + ADP (AK1) (Sus scrofa)
(d)AMP [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Sus scrofa)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Sus scrofa)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Sus scrofa)
AMP [cytosol]
Nucleotide biosynthesis (Sus scrofa)
Purine ribonucleoside monophosphate biosynthesis (Sus scrofa)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Sus scrofa)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Sus scrofa)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Sus scrofa)
AMP [cytosol]
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Sus scrofa)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Sus scrofa)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Sus scrofa)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)
AMP [cytosol]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Sus scrofa)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Sus scrofa)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Sus scrofa)
AMP [cytosol]
Metabolism of vitamins and cofactors (Sus scrofa)
Metabolism of water-soluble vitamins and cofactors (Sus scrofa)
Biotin transport and metabolism (Sus scrofa)
HLCS biotinylates 6x(PCCA:PCCB) (Sus scrofa)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Sus scrofa)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Sus scrofa)
AMP [cytosol]
HLCS biotinylates ACACB (Sus scrofa)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Sus scrofa)
AMP [cytosol]
Molybdenum cofactor biosynthesis (Sus scrofa)
Molybdenum ion transfer onto molybdopterin (Sus scrofa)
AMP [cytosol]
Nicotinate metabolism (Sus scrofa)
NADSYN1 hexamer amidates NAAD to NAD+ (Sus scrofa)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Sus scrofa)
2xTPK1:Mg2+ phosphorylates THMN (Sus scrofa)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Sus scrofa)
2xENPP1 hydrolyzes FAD to FMN (Sus scrofa)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Sus scrofa)
Coenzyme A biosynthesis (Sus scrofa)
2xPPCS ligates PPanK with Cys (Sus scrofa)
AMP [cytosol]
Metabolism of RNA (Sus scrofa)
Deadenylation-dependent mRNA decay (Sus scrofa)
Deadenylation of mRNA (Sus scrofa)
CCR4-NOT complex deadenylates mRNA (Sus scrofa)
AMP [cytosol]
PAN2-PAN3 complex partially deadenylates mRNA (Sus scrofa)
AMP [cytosol]
PARN deadenylates mRNA (Sus scrofa)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Sus scrofa)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Sus scrofa)
AMP [cytosol]
Metabolism of proteins (Sus scrofa)
Post-translational protein modification (Sus scrofa)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Sus scrofa)
Synthesis of diphthamide-EEF2 (Sus scrofa)
DPH6 ligates ammonium to diphthine-EEF2 (Sus scrofa)
AMP [cytosol]
Protein ubiquitination (Sus scrofa)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Sus scrofa)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Sus scrofa)
AMP [cytosol]
Signal Transduction (Sus scrofa)
Intracellular signaling by second messengers (Sus scrofa)
DAG and IP3 signaling (Sus scrofa)
CaM pathway (Sus scrofa)
Calmodulin induced events (Sus scrofa)
Cam-PDE 1 activation (Sus scrofa)
cAMP hydrolysis by Cam-PDE 1 (Sus scrofa)
AMP [cytosol]
MTOR signalling (Sus scrofa)
Energy dependent regulation of mTOR by LKB1-AMPK (Sus scrofa)
AMPK phosphorylates Raptor in the mTORC1 complex (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Activation of cytosolic AMPK by phosphorylation (Sus scrofa)
AMP [cytosol]
Phosphorylated AMPK binds AMP (Sus scrofa)
AMP [cytosol]
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
p-AMPK phosphorylates TSC1:TSC2 (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
AMP [cytosol]
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (i) signalling events (Sus scrofa)
Opioid Signalling (Sus scrofa)
DARPP-32 events (Sus scrofa)
PDE4A,C,D hydrolyse cAMP (Sus scrofa)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Sus scrofa)
AMP [cytosol]
G-protein mediated events (Sus scrofa)
PLC beta mediated events (Sus scrofa)
Ca-dependent events (Sus scrofa)
CaM pathway (Sus scrofa)
Calmodulin induced events (Sus scrofa)
Cam-PDE 1 activation (Sus scrofa)
cAMP hydrolysis by Cam-PDE 1 (Sus scrofa)
AMP [cytosol]
G alpha (s) signalling events (Sus scrofa)
PDE3A hydrolyses cAMP to AMP (Sus scrofa)
AMP [cytosol]
PDE3B hydrolyses cAMP to AMP (Sus scrofa)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Sus scrofa)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Sus scrofa)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Sus scrofa)
Signaling by Insulin receptor (Sus scrofa)
Insulin receptor signalling cascade (Sus scrofa)
IRS-mediated signalling (Sus scrofa)
PI3K Cascade (Sus scrofa)
PKB-mediated events (Sus scrofa)
PDE3B signalling (Sus scrofa)
p-S295-PDE3B hydrolyses cAMP to AMP (Sus scrofa)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Sus scrofa)
IGF1R signaling cascade (Sus scrofa)
IRS-related events triggered by IGF1R (Sus scrofa)
IRS-mediated signalling (Sus scrofa)
PI3K Cascade (Sus scrofa)
PKB-mediated events (Sus scrofa)
PDE3B signalling (Sus scrofa)
p-S295-PDE3B hydrolyses cAMP to AMP (Sus scrofa)
AMP [cytosol]
Autophagy (Xenopus tropicalis)
Macroautophagy (Xenopus tropicalis)
AMPK (complex) phosphorylates ULK1 (complex) (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
Thr-180 of ULK1 is phosphorylated (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:p-S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
ULK complex translocates to the ER (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
ULK1 phosphorylates AMBRA1:BECN1 complex (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
ULK1 phosphorylates ATG13 and RB1CC1 (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:p-ATG13:p-RB1CC1:ATG101 [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
ULK1 phosphorylates Beclin-1 (Xenopus tropicalis)
p-AMPK heterotrimer:AMP:p-T180,S317,467,556,638,T575-ULK1:ATG13:RB1CC1:ATG101 [endoplasmic reticulum membrane] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
Drug ADME (Xenopus tropicalis)
Azathioprine ADME (Xenopus tropicalis)
GMPS dimer transforms 6TXMP to 6TGMP (Xenopus tropicalis)
AMP [cytosol]
Immune System (Xenopus tropicalis)
Adaptive Immune System (Xenopus tropicalis)
Class I MHC mediated antigen processing & presentation (Xenopus tropicalis)
Antigen processing: Ubiquitination & Proteasome degradation (Xenopus tropicalis)
E1 mediated ubiquitin activation (Xenopus tropicalis)
AMP [cytosol]
Polyubiquitination of substrate (Xenopus tropicalis)
AMP [cytosol]
Transfer of Ub from E2 to substrate and release of E2 (Xenopus tropicalis)
AMP [cytosol]
Metabolism (Xenopus tropicalis)
Biological oxidations (Xenopus tropicalis)
Phase I - Functionalization of compounds (Xenopus tropicalis)
Ethanol oxidation (Xenopus tropicalis)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Xenopus tropicalis)
AMP [cytosol]
Phase II - Conjugation of compounds (Xenopus tropicalis)
Cytosolic sulfonation of small molecules (Xenopus tropicalis)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Xenopus tropicalis)
AMP [cytosol]
Integration of energy metabolism (Xenopus tropicalis)
Regulation of insulin secretion (Xenopus tropicalis)
Free fatty acids regulate insulin secretion (Xenopus tropicalis)
Intracellular metabolism of fatty acids regulates insulin secretion (Xenopus tropicalis)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Xenopus tropicalis)
AMP [cytosol]
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Aspartate and asparagine metabolism (Xenopus tropicalis)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Xenopus tropicalis)
AMP [cytosol]
Metabolism of carbohydrates and carbohydrate derivatives (Xenopus tropicalis)
Glucose metabolism (Xenopus tropicalis)
Gluconeogenesis (Xenopus tropicalis)
FBP tetramers hydrolyze F1,6PP to Fru(6)P (Xenopus tropicalis)
AMP [cytosol]
Glycolysis (Xenopus tropicalis)
ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)
AMP [cytosol]
Glycogen metabolism (Xenopus tropicalis)
Glycogen breakdown (glycogenolysis) (Xenopus tropicalis)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Xenopus tropicalis)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Xenopus tropicalis)
AMP [cytosol]
PYGM b dimer:AMP [cytosol] (Xenopus tropicalis)
AMP [cytosol]
Pentose phosphate pathway (Xenopus tropicalis)
5-Phosphoribose 1-diphosphate biosynthesis (Xenopus tropicalis)
PRPS dimers pyrophosphorylate R5P using ATP (Xenopus tropicalis)
AMP [cytosol]
Metabolism of lipids (Xenopus tropicalis)
Fatty acid metabolism (Xenopus tropicalis)
Fatty acyl-CoA biosynthesis (Xenopus tropicalis)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Xenopus tropicalis)
AMP [cytosol]
Synthesis of very long-chain fatty acyl-CoAs (Xenopus tropicalis)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Xenopus tropicalis)
AMP [cytosol]
ACSL3,4 ligate CoA to AA to form AA-CoA (Xenopus tropicalis)
AMP [cytosol]
Ketone body metabolism (Xenopus tropicalis)
Synthesis of Ketone Bodies (Xenopus tropicalis)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Xenopus tropicalis)
AMP [cytosol]
Metabolism of steroids (Xenopus tropicalis)
Bile acid and bile salt metabolism (Xenopus tropicalis)
Recycling of bile acids and salts (Xenopus tropicalis)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
AMP [cytosol]
Synthesis of bile acids and bile salts (Xenopus tropicalis)
Synthesis of bile acids and bile salts via 24-hydroxycholesterol (Xenopus tropicalis)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
AMP [cytosol]
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
AMP [cytosol]
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
AMP [cytosol]
Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol (Xenopus tropicalis)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
AMP [cytosol]
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
AMP [cytosol]
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
AMP [cytosol]
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
(d)ADP or (d)CDP + ADP <=> (d)AMP or (d)CMP + ATP (Xenopus tropicalis)
(d)NMPs [cytosol]
AMP [cytosol]
ADP + ADP <=> AMP + ATP [AK2] (Xenopus tropicalis)
AMP [cytosol]
AK5,7,8,9 phosphorylates (d)NMPs to (d)NDPs (Xenopus tropicalis)
(d)NMPs [cytosol]
AMP [cytosol]
AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)
AMP [cytosol]
Nucleotide biosynthesis (Xenopus tropicalis)
Purine ribonucleoside monophosphate biosynthesis (Xenopus tropicalis)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer (Xenopus tropicalis)
AMP [cytosol]
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Xenopus tropicalis)
AMP [cytosol]
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Xenopus tropicalis)
AMP [cytosol]
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
(d)AMP, (d)GMP, or (d)IMP + H2O => (deoxy)adenosine, (deoxy)guanosine, or (deoxy)inosine + orthophosphate (NT5C1A) (Xenopus tropicalis)
(d)AMP, (d)GMP, (d)IMP [cytosol]
AMP [cytosol]
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Xenopus tropicalis)
AMP [cytosol]
Phosphate bond hydrolysis by NUDT proteins (Xenopus tropicalis)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)
AMP [cytosol]
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)
AMP [cytosol]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
(2'-deoxy)adenosine + ATP => (d)AMP + ADP (ADK) (Xenopus tropicalis)
(d)AMP [cytosol]
AMP [cytosol]
AMP + H2O => IMP + NH4+ (AMPD) (Xenopus tropicalis)
AMP [cytosol]
APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)
AMP [cytosol]
Metabolism of vitamins and cofactors (Xenopus tropicalis)
Metabolism of water-soluble vitamins and cofactors (Xenopus tropicalis)
Biotin transport and metabolism (Xenopus tropicalis)
HLCS biotinylates 6x(PCCA:PCCB) (Xenopus tropicalis)
AMP [cytosol]
HLCS biotinylates 6xMCCC1:6xMCCC2 (Xenopus tropicalis)
AMP [cytosol]
HLCS biotinylates ACACA:Mn2+ (Xenopus tropicalis)
AMP [cytosol]
HLCS biotinylates ACACB (Xenopus tropicalis)
AMP [cytosol]
HLCS biotinylates PC:Mn2+ (Xenopus tropicalis)
AMP [cytosol]
Vitamin B1 (thiamin) metabolism (Xenopus tropicalis)
2xTPK1:Mg2+ phosphorylates THMN (Xenopus tropicalis)
AMP [cytosol]
Vitamin B2 (riboflavin) metabolism (Xenopus tropicalis)
2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)
AMP [cytosol]
Vitamin B5 (pantothenate) metabolism (Xenopus tropicalis)
Coenzyme A biosynthesis (Xenopus tropicalis)
2xPPCS ligates PPanK with Cys (Xenopus tropicalis)
AMP [cytosol]
Metabolism of RNA (Xenopus tropicalis)
Deadenylation-dependent mRNA decay (Xenopus tropicalis)
Deadenylation of mRNA (Xenopus tropicalis)
CCR4-NOT complex deadenylates mRNA (Xenopus tropicalis)
AMP [cytosol]
PARN deadenylates mRNA (Xenopus tropicalis)
AMP [cytosol]
mRNA decay by 3' to 5' exoribonuclease (Xenopus tropicalis)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Xenopus tropicalis)
AMP [cytosol]
Metabolism of proteins (Xenopus tropicalis)
Post-translational protein modification (Xenopus tropicalis)
Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation (Xenopus tropicalis)
Synthesis of diphthamide-EEF2 (Xenopus tropicalis)
DPH6 ligates ammonium to diphthine-EEF2 (Xenopus tropicalis)
AMP [cytosol]
Protein ubiquitination (Xenopus tropicalis)
Synthesis of active ubiquitin: roles of E1 and E2 enzymes (Xenopus tropicalis)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Xenopus tropicalis)
AMP [cytosol]
Signal Transduction (Xenopus tropicalis)
Intracellular signaling by second messengers (Xenopus tropicalis)
DAG and IP3 signaling (Xenopus tropicalis)
CaM pathway (Xenopus tropicalis)
Calmodulin induced events (Xenopus tropicalis)
Cam-PDE 1 activation (Xenopus tropicalis)
cAMP hydrolysis by Cam-PDE 1 (Xenopus tropicalis)
AMP [cytosol]
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (i) signalling events (Xenopus tropicalis)
Opioid Signalling (Xenopus tropicalis)
DARPP-32 events (Xenopus tropicalis)
PDE4A,C,D hydrolyse cAMP (Xenopus tropicalis)
AMP [cytosol]
p-S54-PDE4B hydrolyses cAMP (Xenopus tropicalis)
AMP [cytosol]
G-protein mediated events (Xenopus tropicalis)
PLC beta mediated events (Xenopus tropicalis)
Ca-dependent events (Xenopus tropicalis)
CaM pathway (Xenopus tropicalis)
Calmodulin induced events (Xenopus tropicalis)
Cam-PDE 1 activation (Xenopus tropicalis)
cAMP hydrolysis by Cam-PDE 1 (Xenopus tropicalis)
AMP [cytosol]
G alpha (s) signalling events (Xenopus tropicalis)
PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)
AMP [cytosol]
PDE4A hydrolyses cAMP to AMP (Xenopus tropicalis)
AMP [cytosol]
cAMP degradation by Phosphodiesterases (Xenopus tropicalis)
AMP [cytosol]
Signaling by Receptor Tyrosine Kinases (Xenopus tropicalis)
Signaling by Insulin receptor (Xenopus tropicalis)
Insulin receptor signalling cascade (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PKB-mediated events (Xenopus tropicalis)
PDE3B signalling (Xenopus tropicalis)
p-S295-PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)
AMP [cytosol]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Xenopus tropicalis)
IGF1R signaling cascade (Xenopus tropicalis)
IRS-related events triggered by IGF1R (Xenopus tropicalis)
IRS-mediated signalling (Xenopus tropicalis)
PI3K Cascade (Xenopus tropicalis)
PKB-mediated events (Xenopus tropicalis)
PDE3B signalling (Xenopus tropicalis)
p-S295-PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)
AMP [cytosol]
External Reference Information
External Reference
adenosine 5'-monophosphate(2-) [ChEBI:456215]
Participates
as a component of
PYGM b dimer:AMP [cytosol] (Drosophila melanogaster)
PYGM b dimer:AMP [cytosol] (Canis familiaris)
PYGM b dimer:AMP [cytosol] (Rattus norvegicus)
PYGM b dimer:AMP [cytosol] (Sus scrofa)
PYGM b dimer:AMP [cytosol] (Bos taurus)
PYGM b dimer:AMP [cytosol] (Caenorhabditis elegans)
PYGM b dimer:AMP [cytosol] (Saccharomyces cerevisiae)
PYGM b dimer:AMP [cytosol] (Dictyostelium discoideum)
PYGM b dimer:AMP [cytosol] (Danio rerio)
PYGM b dimer:AMP [cytosol] (Xenopus tropicalis)
PYGM b dimer:AMP [cytosol] (Mus musculus)
PYGM b dimer:AMP [cytosol] (Homo sapiens)
PYGB b dimer:AMP [cytosol] (Homo sapiens)
AMPK gamma:AMP [cytosol] (Homo sapiens)
Ampk gamma:AMP [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Homo sapiens)
p-AMPK heterotrimer:AMP [cytosol] (Bos taurus)
p-AMPK heterotrimer:AMP [cytosol] (Sus scrofa)
p-AMPK heterotrimer:AMP [cytosol] (Mus musculus)
p-AMPK heterotrimer:AMP [cytosol] (Schizosaccharomyces pombe)
p-AMPK heterotrimer:AMP [cytosol] (Xenopus tropicalis)
p-AMPK heterotrimer:AMP [cytosol] (Saccharomyces cerevisiae)
p-AMPK heterotrimer:AMP [cytosol] (Rattus norvegicus)
p-AMPK heterotrimer:AMP [cytosol] (Dictyostelium discoideum)
p-AMPK heterotrimer:AMP [cytosol] (Canis familiaris)
p-AMPK heterotrimer:AMP [cytosol] (Danio rerio)
p-AMPK heterotrimer:AMP [cytosol] (Drosophila melanogaster)
p-AMPK heterotrimer:AMP [cytosol] (Caenorhabditis elegans)
p-AMPK heterotrimer:AMP [cytosol] (Gallus gallus)
as an input of
abacavir + AMP => abacavir monophosphate + adenosine (Homo sapiens)
PYGB dimer, b form + 2 AMP => PYGB b dimer:AMP complex (Homo sapiens)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Saccharomyces cerevisiae)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Dictyostelium discoideum)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Caenorhabditis elegans)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Drosophila melanogaster)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Xenopus tropicalis)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Danio rerio)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Sus scrofa)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Bos taurus)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Canis familiaris)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Rattus norvegicus)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Mus musculus)
PYGM dimer, b form + 2 AMP => PYGM b dimer:AMP complex (Homo sapiens)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Gallus gallus)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Xenopus tropicalis)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Danio rerio)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Sus scrofa)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Bos taurus)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Canis familiaris)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Rattus norvegicus)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Mus musculus)
AMP + H2O => adenosine + orthophosphate [NT5C1B] (Homo sapiens)
AMP + ATP <=> ADP + ADP [AK2] (Plasmodium falciparum)
AMP + ATP <=> ADP + ADP [AK2] (Saccharomyces cerevisiae)
AMP + ATP <=> ADP + ADP [AK2] (Schizosaccharomyces pombe)
AMP + ATP <=> ADP + ADP [AK2] (Dictyostelium discoideum)
AMP + ATP <=> ADP + ADP [AK2] (Caenorhabditis elegans)
AMP + ATP <=> ADP + ADP [AK2] (Drosophila melanogaster)
AMP + ATP <=> ADP + ADP [AK2] (Gallus gallus)
AMP + ATP <=> ADP + ADP [AK2] (Xenopus tropicalis)
AMP + ATP <=> ADP + ADP [AK2] (Danio rerio)
AMP + ATP <=> ADP + ADP [AK2] (Sus scrofa)
AMP + ATP <=> ADP + ADP [AK2] (Bos taurus)
AMP + ATP <=> ADP + ADP [AK2] (Canis familiaris)
AMP + ATP <=> ADP + ADP [AK2] (Rattus norvegicus)
AMP + ATP <=> ADP + ADP [AK2] (Mus musculus)
AMP + ATP <=> ADP + ADP [AK2] (Homo sapiens)
AMP + H2O => IMP + NH4+ (AMPD) (Plasmodium falciparum)
AMP + H2O => IMP + NH4+ (AMPD) (Saccharomyces cerevisiae)
AMP + H2O => IMP + NH4+ (AMPD) (Schizosaccharomyces pombe)
AMP + H2O => IMP + NH4+ (AMPD) (Dictyostelium discoideum)
AMP + H2O => IMP + NH4+ (AMPD) (Caenorhabditis elegans)
AMP + H2O => IMP + NH4+ (AMPD) (Drosophila melanogaster)
AMP + H2O => IMP + NH4+ (AMPD) (Gallus gallus)
AMP + H2O => IMP + NH4+ (AMPD) (Xenopus tropicalis)
AMP + H2O => IMP + NH4+ (AMPD) (Danio rerio)
AMP + H2O => IMP + NH4+ (AMPD) (Sus scrofa)
AMP + H2O => IMP + NH4+ (AMPD) (Bos taurus)
AMP + H2O => IMP + NH4+ (AMPD) (Canis familiaris)
AMP + H2O => IMP + NH4+ (AMPD) (Rattus norvegicus)
AMP + H2O => IMP + NH4+ (AMPD) (Mus musculus)
AMP + H2O => IMP + NH4+ (AMPD) (Homo sapiens)
Phosphorylated AMPK binds AMP (Homo sapiens)
Phosphorylated AMPK binds AMP (Mus musculus)
Phosphorylated AMPK binds AMP (Rattus norvegicus)
Phosphorylated AMPK binds AMP (Canis familiaris)
Phosphorylated AMPK binds AMP (Bos taurus)
Phosphorylated AMPK binds AMP (Sus scrofa)
Phosphorylated AMPK binds AMP (Danio rerio)
Phosphorylated AMPK binds AMP (Gallus gallus)
Phosphorylated AMPK binds AMP (Drosophila melanogaster)
Phosphorylated AMPK binds AMP (Caenorhabditis elegans)
Phosphorylated AMPK binds AMP (Dictyostelium discoideum)
Phosphorylated AMPK binds AMP (Schizosaccharomyces pombe)
Phosphorylated AMPK binds AMP (Saccharomyces cerevisiae)
as an output of
adenylosuccinate => adenosine 5'-monophosphate (AMP) + fumarate (Gallus gallus)
xanthosine 5'-monophosphate (XMP) + L-glutamine + ATP + H2O => guanosine 5'-monophosphate (GMP) + L-glutamate + adenosine 5'-monophosphate (AMP) + pyrophosphate (Gallus gallus)
FadD26, FadD28 transfer LCFA adenylate ester to Pks5 (Mycobacterium tuberculosis)
glucosaminyl-inositol and cysteine are ligated to desacetylmycothiol (Mycobacterium tuberculosis)
sulfite results from reduction of APS (Mycobacterium tuberculosis)
aspartate + tRNA(Asp) + ATP => Asp-tRNA(Asp) + AMP + pyrophosphate (Homo sapiens)
serine + tRNA(Ser) + ATP => Ser-tRNA(Ser) + AMP + pyrophosphate (Homo sapiens)
alanine + tRNA(Ala) + ATP => Ala-tRNA(Ala) + AMP + pyrophosphate (Homo sapiens)
proline + tRNA(Pro) + ATP => Pro-tRNA(Pro) + AMP + pyrophosphate (Homo sapiens)
arginine + tRNA(Arg) + ATP => Arg-tRNA(Arg) + AMP + pyrophosphate (Homo sapiens)
asparagine + tRNA(Asn) + ATP => Asn-tRNA(Asn) + AMP + pyrophosphate (Homo sapiens)
glycine + tRNA(Gly) + ATP => Gly-tRNA(Gly) + AMP + pyrophosphate (Homo sapiens)
isoleucine + tRNA(Ile) + ATP => Ile-tRNA(Ile) + AMP + pyrophosphate (Homo sapiens)
glutamate + tRNA(Glu) + ATP => Glu-tRNA(Glu) + AMP + pyrophosphate (Homo sapiens)
valine + tRNA(Val) + ATP => Val-tRNA(Val) + AMP + pyrophosphate (Homo sapiens)
phenylalanine + tRNA(Phe) + ATP => Phe-tRNA(Phe) + AMP + pyrophosphate (Homo sapiens)
lysine + tRNA(Lys) + ATP => Lys-tRNA(Lys) + AMP + pyrophosphate (Homo sapiens)
tryptophan + tRNA(Trp) + ATP => Trp-tRNA(Trp) + AMP + pyrophosphate (Homo sapiens)
glutamine + tRNA(Gln) + ATP => Gln-tRNA(Gln) + AMP + pyrophosphate (Homo sapiens)
cysteine + tRNA(Cys) + ATP => Cys-tRNA(Cys) + AMP + pyrophosphate (Homo sapiens)
tyrosine + tRNA(Tyr) + ATP =>Tyr-tRNA(Tyr) + AMP + pyrophosphate (Homo sapiens)
threonine + tRNA(Thr) + ATP => Thr-tRNA(Thr) + AMP + pyrophosphate (Homo sapiens)
leucine + tRNA(Leu) + ATP => Leu-tRNA(Leu) + AMP + pyrophosphate (Homo sapiens)
histidine + tRNA(His) + ATP => His-tRNA(His) + AMP + pyrophosphate (Homo sapiens)
UBA6 conjugates ubiquitin to UBA6 in the cytosol (Homo sapiens)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Plasmodium falciparum)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Saccharomyces cerevisiae)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Schizosaccharomyces pombe)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Dictyostelium discoideum)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Caenorhabditis elegans)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Drosophila melanogaster)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Gallus gallus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Xenopus tropicalis)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Danio rerio)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Sus scrofa)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Bos taurus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Canis familiaris)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Rattus norvegicus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Mus musculus)
UBA1 conjugates ubiquitin to UBA1 in the cytosol (Homo sapiens)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Caenorhabditis elegans)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Gallus gallus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Xenopus tropicalis)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Danio rerio)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Sus scrofa)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Bos taurus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Rattus norvegicus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Mus musculus)
AACS ligates CoA-SH to ACA, forming ACA-CoA (Homo sapiens)
ISGylation of DDX58 (RIG-I) (Dictyostelium discoideum)
ISGylation of DDX58 (RIG-I) (Caenorhabditis elegans)
ISGylation of DDX58 (RIG-I) (Sus scrofa)
ISGylation of DDX58 (RIG-I) (Bos taurus)
ISGylation of DDX58 (RIG-I) (Rattus norvegicus)
ISGylation of DDX58 (RIG-I) (Mus musculus)
ISGylation of DDX58 (RIG-I) (Homo sapiens)
GMPS dimer transforms 6TXMP to 6TGMP (Plasmodium falciparum)
GMPS dimer transforms 6TXMP to 6TGMP (Saccharomyces cerevisiae)
GMPS dimer transforms 6TXMP to 6TGMP (Schizosaccharomyces pombe)
GMPS dimer transforms 6TXMP to 6TGMP (Dictyostelium discoideum)
GMPS dimer transforms 6TXMP to 6TGMP (Caenorhabditis elegans)
GMPS dimer transforms 6TXMP to 6TGMP (Drosophila melanogaster)
GMPS dimer transforms 6TXMP to 6TGMP (Gallus gallus)
GMPS dimer transforms 6TXMP to 6TGMP (Xenopus tropicalis)
GMPS dimer transforms 6TXMP to 6TGMP (Sus scrofa)
GMPS dimer transforms 6TXMP to 6TGMP (Bos taurus)
GMPS dimer transforms 6TXMP to 6TGMP (Canis familiaris)
GMPS dimer transforms 6TXMP to 6TGMP (Rattus norvegicus)
GMPS dimer transforms 6TXMP to 6TGMP (Mus musculus)
GMPS dimer transforms 6TXMP to 6TGMP (Homo sapiens)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
DHCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
DHCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Saccharomyces cerevisiae)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Caenorhabditis elegans)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Drosophila melanogaster)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Gallus gallus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Xenopus tropicalis)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Sus scrofa)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Bos taurus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Canis familiaris)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Rattus norvegicus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Mus musculus)
3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS) (Homo sapiens)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Saccharomyces cerevisiae)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Caenorhabditis elegans)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Drosophila melanogaster)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Gallus gallus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Xenopus tropicalis)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Danio rerio)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Sus scrofa)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Bos taurus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Canis familiaris)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Rattus norvegicus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Mus musculus)
Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS) (Homo sapiens)
HLCS biotinylates ACACB (Plasmodium falciparum)
HLCS biotinylates ACACB (Saccharomyces cerevisiae)
HLCS biotinylates ACACB (Schizosaccharomyces pombe)
HLCS biotinylates ACACB (Dictyostelium discoideum)
HLCS biotinylates ACACB (Caenorhabditis elegans)
HLCS biotinylates ACACB (Drosophila melanogaster)
HLCS biotinylates ACACB (Xenopus tropicalis)
HLCS biotinylates ACACB (Sus scrofa)
HLCS biotinylates ACACB (Bos taurus)
HLCS biotinylates ACACB (Canis familiaris)
HLCS biotinylates ACACB (Rattus norvegicus)
HLCS biotinylates ACACB (Mus musculus)
HLCS biotinylates ACACB (Homo sapiens)
2xENPP1 hydrolyzes FAD to FMN (Saccharomyces cerevisiae)
2xENPP1 hydrolyzes FAD to FMN (Schizosaccharomyces pombe)
2xENPP1 hydrolyzes FAD to FMN (Dictyostelium discoideum)
2xENPP1 hydrolyzes FAD to FMN (Caenorhabditis elegans)
2xENPP1 hydrolyzes FAD to FMN (Xenopus tropicalis)
2xENPP1 hydrolyzes FAD to FMN (Danio rerio)
2xENPP1 hydrolyzes FAD to FMN (Sus scrofa)
2xENPP1 hydrolyzes FAD to FMN (Bos taurus)
2xENPP1 hydrolyzes FAD to FMN (Canis familiaris)
2xENPP1 hydrolyzes FAD to FMN (Rattus norvegicus)
2xENPP1 hydrolyzes FAD to FMN (Mus musculus)
2xENPP1 hydrolyzes FAD to FMN (Homo sapiens)
2xPPCS ligates PPanK with Cys (Plasmodium falciparum)
2xPPCS ligates PPanK with Cys (Saccharomyces cerevisiae)
2xPPCS ligates PPanK with Cys (Schizosaccharomyces pombe)
2xPPCS ligates PPanK with Cys (Dictyostelium discoideum)
2xPPCS ligates PPanK with Cys (Caenorhabditis elegans)
2xPPCS ligates PPanK with Cys (Drosophila melanogaster)
2xPPCS ligates PPanK with Cys (Gallus gallus)
2xPPCS ligates PPanK with Cys (Xenopus tropicalis)
2xPPCS ligates PPanK with Cys (Danio rerio)
2xPPCS ligates PPanK with Cys (Sus scrofa)
2xPPCS ligates PPanK with Cys (Bos taurus)
2xPPCS ligates PPanK with Cys (Canis familiaris)
2xPPCS ligates PPanK with Cys (Rattus norvegicus)
2xPPCS ligates PPanK with Cys (Mus musculus)
2xPPCS ligates PPanK with Cys (Homo sapiens)
Molybdenum ion transfer onto molybdopterin (Dictyostelium discoideum)
Molybdenum ion transfer onto molybdopterin (Caenorhabditis elegans)
Molybdenum ion transfer onto molybdopterin (Drosophila melanogaster)
Molybdenum ion transfer onto molybdopterin (Gallus gallus)
Molybdenum ion transfer onto molybdopterin (Sus scrofa)
Molybdenum ion transfer onto molybdopterin (Bos taurus)
Molybdenum ion transfer onto molybdopterin (Canis familiaris)
Molybdenum ion transfer onto molybdopterin (Rattus norvegicus)
Molybdenum ion transfer onto molybdopterin (Mus musculus)
Transfer of sulfur from MOCS3-S-S onto MOCS2A (Homo sapiens)
Molybdenum ion transfer onto molybdopterin (Homo sapiens)
2xTPK1:Mg2+ phosphorylates THMN (Plasmodium falciparum)
2xTPK1:Mg2+ phosphorylates THMN (Saccharomyces cerevisiae)
2xTPK1:Mg2+ phosphorylates THMN (Schizosaccharomyces pombe)
2xTPK1:Mg2+ phosphorylates THMN (Dictyostelium discoideum)
2xTPK1:Mg2+ phosphorylates THMN (Caenorhabditis elegans)
2xTPK1:Mg2+ phosphorylates THMN (Drosophila melanogaster)
2xTPK1:Mg2+ phosphorylates THMN (Gallus gallus)
2xTPK1:Mg2+ phosphorylates THMN (Xenopus tropicalis)
2xTPK1:Mg2+ phosphorylates THMN (Danio rerio)
2xTPK1:Mg2+ phosphorylates THMN (Sus scrofa)
2xTPK1:Mg2+ phosphorylates THMN (Bos taurus)
2xTPK1:Mg2+ phosphorylates THMN (Canis familiaris)
2xTPK1:Mg2+ phosphorylates THMN (Rattus norvegicus)
2xTPK1:Mg2+ phosphorylates THMN (Mus musculus)
2xTPK1:Mg2+ phosphorylates THMN (Homo sapiens)
HLCS biotinylates 6x(PCCA:PCCB) (Dictyostelium discoideum)
HLCS biotinylates 6x(PCCA:PCCB) (Caenorhabditis elegans)
HLCS biotinylates 6x(PCCA:PCCB) (Gallus gallus)
HLCS biotinylates 6x(PCCA:PCCB) (Xenopus tropicalis)
HLCS biotinylates 6x(PCCA:PCCB) (Sus scrofa)
HLCS biotinylates 6x(PCCA:PCCB) (Bos taurus)
HLCS biotinylates 6x(PCCA:PCCB) (Canis familiaris)
HLCS biotinylates 6x(PCCA:PCCB) (Rattus norvegicus)
HLCS biotinylates 6x(PCCA:PCCB) (Mus musculus)
HLCS biotinylates 6x(PCCA:PCCB) (Homo sapiens)
HLCS biotinylates PC:Mn2+ (Saccharomyces cerevisiae)
HLCS biotinylates PC:Mn2+ (Schizosaccharomyces pombe)
HLCS biotinylates PC:Mn2+ (Caenorhabditis elegans)
HLCS biotinylates PC:Mn2+ (Drosophila melanogaster)
HLCS biotinylates PC:Mn2+ (Xenopus tropicalis)
HLCS biotinylates PC:Mn2+ (Sus scrofa)
HLCS biotinylates PC:Mn2+ (Bos taurus)
HLCS biotinylates PC:Mn2+ (Canis familiaris)
HLCS biotinylates PC:Mn2+ (Rattus norvegicus)
HLCS biotinylates PC:Mn2+ (Mus musculus)
HLCS biotinylates PC:Mn2+ (Homo sapiens)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Dictyostelium discoideum)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Caenorhabditis elegans)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Drosophila melanogaster)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Gallus gallus)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Xenopus tropicalis)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Sus scrofa)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Bos taurus)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Canis familiaris)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Rattus norvegicus)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Mus musculus)
HLCS biotinylates 6xMCCC1:6xMCCC2 (Homo sapiens)
HLCS biotinylates ACACA:Mn2+ (Plasmodium falciparum)
HLCS biotinylates ACACA:Mn2+ (Saccharomyces cerevisiae)
HLCS biotinylates ACACA:Mn2+ (Schizosaccharomyces pombe)
HLCS biotinylates ACACA:Mn2+ (Dictyostelium discoideum)
HLCS biotinylates ACACA:Mn2+ (Caenorhabditis elegans)
HLCS biotinylates ACACA:Mn2+ (Drosophila melanogaster)
HLCS biotinylates ACACA:Mn2+ (Gallus gallus)
HLCS biotinylates ACACA:Mn2+ (Xenopus tropicalis)
HLCS biotinylates ACACA:Mn2+ (Sus scrofa)
HLCS biotinylates ACACA:Mn2+ (Bos taurus)
HLCS biotinylates ACACA:Mn2+ (Canis familiaris)
HLCS biotinylates ACACA:Mn2+ (Rattus norvegicus)
HLCS biotinylates ACACA:Mn2+ (Mus musculus)
HLCS biotinylates ACACA:Mn2+ (Homo sapiens)
DPH6 ligates ammonium to diphthine-EEF2 (Saccharomyces cerevisiae)
DPH6 ligates ammonium to diphthine-EEF2 (Schizosaccharomyces pombe)
DPH6 ligates ammonium to diphthine-EEF2 (Dictyostelium discoideum)
DPH6 ligates ammonium to diphthine-EEF2 (Caenorhabditis elegans)
DPH6 ligates ammonium to diphthine-EEF2 (Drosophila melanogaster)
DPH6 ligates ammonium to diphthine-EEF2 (Gallus gallus)
DPH6 ligates ammonium to diphthine-EEF2 (Xenopus tropicalis)
DPH6 ligates ammonium to diphthine-EEF2 (Sus scrofa)
DPH6 ligates ammonium to diphthine-EEF2 (Bos taurus)
DPH6 ligates ammonium to diphthine-EEF2 (Canis familiaris)
DPH6 ligates ammonium to diphthine-EEF2 (Rattus norvegicus)
DPH6 ligates ammonium to diphthine-EEF2 (Mus musculus)
DPH6 ligates ammonium to diphthine-EEF2 (Homo sapiens)
CCR4-NOT(Cnot6l) deadenylates mRNA in CCR4-NOT(Cnot6l):Zfp36l2:mRNA (Mus musculus)
CCR4-NOT(CNOT6L) deadenylates mRNA in CCR4-NOT(CNOT6L):ZFP36L2:mRNA (Homo sapiens)
CCR4-NOT deadenylates mRNA in CCR4-NOT:Btg4:Pabpn1l:mRNP (Mus musculus)
CCR4-NOT deadenylates mRNA in CCR4-NOT:BTG4:PABPN1L:mRNP (Homo sapiens)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Dictyostelium discoideum)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Caenorhabditis elegans)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Drosophila melanogaster)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Gallus gallus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Xenopus tropicalis)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Sus scrofa)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Bos taurus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Canis familiaris)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Rattus norvegicus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Mus musculus)
Adenosine 3',5'-bisphosphate (PAP) + H2O => AMP + orthophosphate (Homo sapiens)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Plasmodium falciparum)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Saccharomyces cerevisiae)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Schizosaccharomyces pombe)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Dictyostelium discoideum)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Caenorhabditis elegans)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Drosophila melanogaster)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Gallus gallus)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Danio rerio)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Bos taurus)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Canis familiaris)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Rattus norvegicus)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Mus musculus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Plasmodium falciparum)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Saccharomyces cerevisiae)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Schizosaccharomyces pombe)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Dictyostelium discoideum)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Caenorhabditis elegans)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Drosophila melanogaster)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Gallus gallus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Danio rerio)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Bos taurus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Canis familiaris)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Rattus norvegicus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Mus musculus)
NEDD8 covalently binds catalytic cysteine of UBA3:NAE1 (Homo sapiens)
NEDD8-UBA3:NAE1 binds a second NEDD8 (Homo sapiens)
PDE4D in PDE4D:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP (Bos taurus)
PDE4D5 in p-S26-ANXA2:PP2A:PDE4D5:ITGA5:ITGB1:fibronectin hydrolyzes cAMP to yield AMP (Homo sapiens)
PDE12 cleaves 2'-5' oligoadenylates (Caenorhabditis elegans)
PDE12 cleaves 2'-5' oligoadenylates (Drosophila melanogaster)
PDE12 cleaves 2'-5' oligoadenylates (Gallus gallus)
PDE12 cleaves 2'-5' oligoadenylates (Sus scrofa)
PDE12 cleaves 2'-5' oligoadenylates (Bos taurus)
PDE12 cleaves 2'-5' oligoadenylates (Canis familiaris)
PDE12 cleaves 2'-5' oligoadenylates (Rattus norvegicus)
PDE12 cleaves 2'-5' oligoadenylates (Mus musculus)
PDE12 cleaves 2'-5' oligoadenylates (Homo sapiens)
Viral 2',5'-PDE cleaves 2'-5' oligoadenylates (Homo sapiens)
p-S54-PDE4B hydrolyses cAMP (Plasmodium falciparum)
p-S54-PDE4B hydrolyses cAMP (Dictyostelium discoideum)
p-S54-PDE4B hydrolyses cAMP (Caenorhabditis elegans)
p-S54-PDE4B hydrolyses cAMP (Drosophila melanogaster)
p-S54-PDE4B hydrolyses cAMP (Gallus gallus)
p-S54-PDE4B hydrolyses cAMP (Xenopus tropicalis)
p-S54-PDE4B hydrolyses cAMP (Sus scrofa)
p-S54-PDE4B hydrolyses cAMP (Bos taurus)
p-S54-PDE4B hydrolyses cAMP (Rattus norvegicus)
p-S54-PDE4B hydrolyses cAMP (Mus musculus)
p-S54-PDE4B hydrolyses cAMP (Homo sapiens)
p-S54-PDE4B hydrolyses cAMP (Canis familiaris)
PDE4A,C,D hydrolyse cAMP (Plasmodium falciparum)
PDE4A,C,D hydrolyse cAMP (Dictyostelium discoideum)
PDE4A,C,D hydrolyse cAMP (Caenorhabditis elegans)
PDE4A,C,D hydrolyse cAMP (Drosophila melanogaster)
PDE4A,C,D hydrolyse cAMP (Gallus gallus)
PDE4A,C,D hydrolyse cAMP (Xenopus tropicalis)
PDE4A,C,D hydrolyse cAMP (Sus scrofa)
PDE4A,C,D hydrolyse cAMP (Bos taurus)
PDE4A,C,D hydrolyse cAMP (Rattus norvegicus)
PDE4A,C,D hydrolyse cAMP (Mus musculus)
PDE4A,C,D hydrolyse cAMP (Homo sapiens)
PDE4A,C,D hydrolyse cAMP (Canis familiaris)
PDE4A hydrolyses cAMP to AMP (Plasmodium falciparum)
PDE4A hydrolyses cAMP to AMP (Dictyostelium discoideum)
PDE4A hydrolyses cAMP to AMP (Caenorhabditis elegans)
PDE4A hydrolyses cAMP to AMP (Drosophila melanogaster)
PDE4A hydrolyses cAMP to AMP (Xenopus tropicalis)
PDE4A hydrolyses cAMP to AMP (Sus scrofa)
PDE4A hydrolyses cAMP to AMP (Bos taurus)
PDE4A hydrolyses cAMP to AMP (Rattus norvegicus)
PDE4A hydrolyses cAMP to AMP (Mus musculus)
PDE4A hydrolyses cAMP to AMP (Homo sapiens)
PDE4A hydrolyses cAMP to AMP (Canis familiaris)
cAMP degradation by Phosphodiesterases (Plasmodium falciparum)
cAMP degradation by Phosphodiesterases (Dictyostelium discoideum)
cAMP degradation by Phosphodiesterases (Caenorhabditis elegans)
cAMP degradation by Phosphodiesterases (Drosophila melanogaster)
cAMP degradation by Phosphodiesterases (Gallus gallus)
cAMP degradation by Phosphodiesterases (Xenopus tropicalis)
cAMP degradation by Phosphodiesterases (Danio rerio)
cAMP degradation by Phosphodiesterases (Sus scrofa)
cAMP degradation by Phosphodiesterases (Bos taurus)
cAMP degradation by Phosphodiesterases (Rattus norvegicus)
cAMP degradation by Phosphodiesterases (Mus musculus)
cAMP degradation by Phosphodiesterases (Homo sapiens)
cAMP degradation by Phosphodiesterases (Canis familiaris)
PDE3A hydrolyses cAMP to AMP (Plasmodium falciparum)
PDE3A hydrolyses cAMP to AMP (Dictyostelium discoideum)
PDE3A hydrolyses cAMP to AMP (Caenorhabditis elegans)
PDE3A hydrolyses cAMP to AMP (Gallus gallus)
PDE3A hydrolyses cAMP to AMP (Sus scrofa)
PDE3A hydrolyses cAMP to AMP (Bos taurus)
PDE3A hydrolyses cAMP to AMP (Rattus norvegicus)
PDE3A hydrolyses cAMP to AMP (Mus musculus)
PDE3A hydrolyses cAMP to AMP (Homo sapiens)
PDE3A hydrolyses cAMP to AMP (Canis familiaris)
PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)
PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)
PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)
PDE3B hydrolyses cAMP to AMP (Gallus gallus)
PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)
PDE3B hydrolyses cAMP to AMP (Sus scrofa)
PDE3B hydrolyses cAMP to AMP (Bos taurus)
PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)
PDE3B hydrolyses cAMP to AMP (Mus musculus)
PDE3B hydrolyses cAMP to AMP (Homo sapiens)
PDE3B hydrolyses cAMP to AMP (Canis familiaris)
tRNA(Sec) is serylated to Ser-tRNA(Sec) by SARS dimer (Homo sapiens)
SEPHS2 phosphorylates H2Se to form SELP (Plasmodium falciparum)
SEPHS2 phosphorylates H2Se to form SELP (Dictyostelium discoideum)
SEPHS2 phosphorylates H2Se to form SELP (Caenorhabditis elegans)
SEPHS2 phosphorylates H2Se to form SELP (Drosophila melanogaster)
SEPHS2 phosphorylates H2Se to form SELP (Danio rerio)
SEPHS2 phosphorylates H2Se to form SELP (Sus scrofa)
SEPHS2 phosphorylates H2Se to form SELP (Canis familiaris)
SEPHS2 phosphorylates H2Se to form SELP (Rattus norvegicus)
SEPHS2 phosphorylates H2Se to form SELP (Mus musculus)
SEPHS2 phosphorylates H2Se to form SELP (Homo sapiens)
tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars (Vigna radiata var. radiata)
tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by Mars (Triticum aestivum)
tRNA(Met) is selenomethionylated to SeMet-tRNA(Met) by multisynthetase complex (Homo sapiens)
NADSYN1 hexamer amidates NAAD to NAD+ (Plasmodium falciparum)
NADSYN1 hexamer amidates NAAD to NAD+ (Saccharomyces cerevisiae)
NADSYN1 hexamer amidates NAAD to NAD+ (Schizosaccharomyces pombe)
NADSYN1 hexamer amidates NAAD to NAD+ (Dictyostelium discoideum)
NADSYN1 hexamer amidates NAAD to NAD+ (Caenorhabditis elegans)
NADSYN1 hexamer amidates NAAD to NAD+ (Drosophila melanogaster)
NADSYN1 hexamer amidates NAAD to NAD+ (Gallus gallus)
NADSYN1 hexamer amidates NAAD to NAD+ (Danio rerio)
NADSYN1 hexamer amidates NAAD to NAD+ (Sus scrofa)
NADSYN1 hexamer amidates NAAD to NAD+ (Bos taurus)
NADSYN1 hexamer amidates NAAD to NAD+ (Canis familiaris)
NADSYN1 hexamer amidates NAAD to NAD+ (Rattus norvegicus)
NADSYN1 hexamer amidates NAAD to NAD+ (Mus musculus)
NADSYN1 hexamer amidates NAAD to NAD+ (Homo sapiens)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Plasmodium falciparum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Saccharomyces cerevisiae)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Schizosaccharomyces pombe)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Dictyostelium discoideum)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Caenorhabditis elegans)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Drosophila melanogaster)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Gallus gallus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Xenopus tropicalis)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Sus scrofa)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Bos taurus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Canis familiaris)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Rattus norvegicus)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Homo sapiens)
acetate + CoA + ATP => acetyl-CoA + AMP + pyrophosphate [cytosolic] (Mus musculus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Saccharomyces cerevisiae)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Schizosaccharomyces pombe)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Caenorhabditis elegans)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Drosophila melanogaster)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Gallus gallus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Xenopus tropicalis)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Danio rerio)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Sus scrofa)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Bos taurus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Canis familiaris)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Rattus norvegicus)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Homo sapiens)
ACSL3,4 ligates coenzyme A (CoA-SH) to palmitate yielding palmitoyl-coenzyme A in the pancreatic beta cell (Mus musculus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Saccharomyces cerevisiae)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Caenorhabditis elegans)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Drosophila melanogaster)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Gallus gallus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Xenopus tropicalis)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Sus scrofa)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Bos taurus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Canis familiaris)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Rattus norvegicus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Mus musculus)
SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA (Homo sapiens)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Plasmodium falciparum)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Saccharomyces cerevisiae)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Schizosaccharomyces pombe)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Dictyostelium discoideum)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Caenorhabditis elegans)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Drosophila melanogaster)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Gallus gallus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Xenopus tropicalis)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Danio rerio)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Sus scrofa)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Bos taurus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Canis familiaris)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Rattus norvegicus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Mus musculus)
ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA (Homo sapiens)
ACSL3,4 ligate CoA to AA to form AA-CoA (Saccharomyces cerevisiae)
ACSL3,4 ligate CoA to AA to form AA-CoA (Schizosaccharomyces pombe)
ACSL3,4 ligate CoA to AA to form AA-CoA (Caenorhabditis elegans)
ACSL3,4 ligate CoA to AA to form AA-CoA (Drosophila melanogaster)
ACSL3,4 ligate CoA to AA to form AA-CoA (Gallus gallus)
ACSL3,4 ligate CoA to AA to form AA-CoA (Xenopus tropicalis)
ACSL3,4 ligate CoA to AA to form AA-CoA (Danio rerio)
ACSL3,4 ligate CoA to AA to form AA-CoA (Sus scrofa)
ACSL3,4 ligate CoA to AA to form AA-CoA (Bos taurus)
ACSL3,4 ligate CoA to AA to form AA-CoA (Canis familiaris)
ACSL3,4 ligate CoA to AA to form AA-CoA (Rattus norvegicus)
ACSL3,4 ligate CoA to AA to form AA-CoA (Mus musculus)
ACSL3,4 ligate CoA to AA to form AA-CoA (Homo sapiens)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Dictyostelium discoideum)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Drosophila melanogaster)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Gallus gallus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Sus scrofa)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Canis familiaris)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Rattus norvegicus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Mus musculus)
ACSBG1,2 ligates CoA-SH to VLCFA, forming VLCFA-CoA (Homo sapiens)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Dictyostelium discoideum)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Drosophila melanogaster)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Gallus gallus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Sus scrofa)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Bos taurus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Canis familiaris)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Mus musculus)
PMP34-mediated exchange of cytosolic ATP for peroxisomal AMP (Homo sapiens)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Homo sapiens)
PYGB b dimer:AMP complex => PGYB dimer, b form + 2 AMP (Homo sapiens)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Saccharomyces cerevisiae)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Dictyostelium discoideum)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Caenorhabditis elegans)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Drosophila melanogaster)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Xenopus tropicalis)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Danio rerio)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Sus scrofa)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Bos taurus)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Canis familiaris)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Rattus norvegicus)
PYGM b dimer:AMP complex => PYGM dimer, b form + 2 AMP (Mus musculus)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Saccharomyces cerevisiae)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Schizosaccharomyces pombe)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Dictyostelium discoideum)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Caenorhabditis elegans)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Gallus gallus)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Danio rerio)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Bos taurus)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Canis familiaris)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Mus musculus)
Cytosolic NUDT5 hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Gallus gallus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Xenopus tropicalis)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Danio rerio)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Sus scrofa)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Bos taurus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Canis familiaris)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Rattus norvegicus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Mus musculus)
ADPRM hydrolyses ADP-ribose to R5P and AMP (Homo sapiens)
ADP + ADP <=> AMP + ATP [AK2] (Plasmodium falciparum)
ADP + ADP <=> AMP + ATP [AK2] (Saccharomyces cerevisiae)
ADP + ADP <=> AMP + ATP [AK2] (Schizosaccharomyces pombe)
ADP + ADP <=> AMP + ATP [AK2] (Dictyostelium discoideum)
ADP + ADP <=> AMP + ATP [AK2] (Caenorhabditis elegans)
ADP + ADP <=> AMP + ATP [AK2] (Gallus gallus)
ADP + ADP <=> AMP + ATP [AK2] (Xenopus tropicalis)
ADP + ADP <=> AMP + ATP [AK2] (Danio rerio)
ADP + ADP <=> AMP + ATP [AK2] (Sus scrofa)
ADP + ADP <=> AMP + ATP [AK2] (Bos taurus)
ADP + ADP <=> AMP + ATP [AK2] (Canis familiaris)
ADP + ADP <=> AMP + ATP [AK2] (Rattus norvegicus)
ADP + ADP <=> AMP + ATP [AK2] (Mus musculus)
ADP + ADP <=> AMP + ATP [AK2] (Homo sapiens)
ADP + ADP <=> AMP + ATP [AK2] (Drosophila melanogaster)
APRT catalyzes the conversion of adenine to AMP (Saccharomyces cerevisiae)
APRT catalyzes the conversion of adenine to AMP (Schizosaccharomyces pombe)
APRT catalyzes the conversion of adenine to AMP (Caenorhabditis elegans)
APRT catalyzes the conversion of adenine to AMP (Drosophila melanogaster)
APRT catalyzes the conversion of adenine to AMP (Gallus gallus)
APRT catalyzes the conversion of adenine to AMP (Xenopus tropicalis)
APRT catalyzes the conversion of adenine to AMP (Danio rerio)
APRT catalyzes the conversion of adenine to AMP (Sus scrofa)
APRT catalyzes the conversion of adenine to AMP (Bos taurus)
APRT catalyzes the conversion of adenine to AMP (Canis familiaris)
APRT catalyzes the conversion of adenine to AMP (Rattus norvegicus)
APRT catalyzes the conversion of adenine to AMP (Mus musculus)
APRT catalyzes the conversion of adenine to AMP (Homo sapiens)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Plasmodium falciparum)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Saccharomyces cerevisiae)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Schizosaccharomyces pombe)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Dictyostelium discoideum)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Caenorhabditis elegans)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Drosophila melanogaster)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Gallus gallus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Xenopus tropicalis)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Sus scrofa)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Bos taurus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Canis familiaris)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Rattus norvegicus)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Mus musculus)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Saccharomyces cerevisiae)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Schizosaccharomyces pombe)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Caenorhabditis elegans)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Drosophila melanogaster)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Gallus gallus)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Xenopus tropicalis)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Sus scrofa)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Bos taurus)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Canis familiaris)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Rattus norvegicus)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Mus musculus)
PRPS dimers pyrophosphorylate R5P using ATP (Plasmodium falciparum)
PRPS dimers pyrophosphorylate R5P using ATP (Saccharomyces cerevisiae)
PRPS dimers pyrophosphorylate R5P using ATP (Schizosaccharomyces pombe)
PRPS dimers pyrophosphorylate R5P using ATP (Dictyostelium discoideum)
PRPS dimers pyrophosphorylate R5P using ATP (Gallus gallus)
PRPS dimers pyrophosphorylate R5P using ATP (Xenopus tropicalis)
PRPS dimers pyrophosphorylate R5P using ATP (Danio rerio)
PRPS dimers pyrophosphorylate R5P using ATP (Sus scrofa)
PRPS dimers pyrophosphorylate R5P using ATP (Bos taurus)
PRPS dimers pyrophosphorylate R5P using ATP (Canis familiaris)
PRPS dimers pyrophosphorylate R5P using ATP (Rattus norvegicus)
PRPS dimers pyrophosphorylate R5P using ATP (Homo sapiens)
PRPS dimers pyrophosphorylate R5P using ATP (Mus musculus)
adenylosuccinate => adenosine 5'-monophosphate + fumarate (Homo sapiens)
XMP + L-Glutamine + ATP + H2O => GMP + L-Glutamate + AMP + pyrophosphate (Homo sapiens)
methionine + tRNA(Met) + ATP => Met-tRNA(Met) + AMP + pyrophosphate (Homo sapiens)
ISGylation of host proteins (Dictyostelium discoideum)
ISGylation of host proteins (Caenorhabditis elegans)
ISGylation of host proteins (Drosophila melanogaster)
ISGylation of host proteins (Sus scrofa)
ISGylation of host proteins (Bos taurus)
ISGylation of host proteins (Rattus norvegicus)
ISGylation of host proteins (Mus musculus)
ISGylation of host proteins (Homo sapiens)
ISGylation of protein phosphatase 1 beta (PP2CB) (Caenorhabditis elegans)
ISGylation of protein phosphatase 1 beta (PP2CB) (Drosophila melanogaster)
ISGylation of protein phosphatase 1 beta (PP2CB) (Sus scrofa)
ISGylation of protein phosphatase 1 beta (PP2CB) (Bos taurus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Rattus norvegicus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Mus musculus)
ISGylation of protein phosphatase 1 beta (PP2CB) (Homo sapiens)
ISGylation of E2 conjugating enzymes (Dictyostelium discoideum)
ISGylation of E2 conjugating enzymes (Caenorhabditis elegans)
ISGylation of E2 conjugating enzymes (Drosophila melanogaster)
ISGylation of E2 conjugating enzymes (Sus scrofa)
ISGylation of E2 conjugating enzymes (Bos taurus)
ISGylation of E2 conjugating enzymes (Rattus norvegicus)
ISGylation of E2 conjugating enzymes (Mus musculus)
ISGylation of E2 conjugating enzymes (Homo sapiens)
ISGylation of host protein filamin B (Dictyostelium discoideum)
ISGylation of host protein filamin B (Caenorhabditis elegans)
ISGylation of host protein filamin B (Drosophila melanogaster)
ISGylation of host protein filamin B (Sus scrofa)
ISGylation of host protein filamin B (Bos taurus)
ISGylation of host protein filamin B (Rattus norvegicus)
ISGylation of host protein filamin B (Mus musculus)
ISGylation of host protein filamin B (Homo sapiens)
ISGylation of viral protein NS1 (Homo sapiens)
ISGylation of PKR (Caenorhabditis elegans)
ISGylation of PKR (Drosophila melanogaster)
ISGylation of PKR (Sus scrofa)
ISGylation of PKR (Bos taurus)
ISGylation of PKR (Rattus norvegicus)
ISGylation of PKR (Mus musculus)
ISGylation of PKR (Homo sapiens)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Saccharomyces cerevisiae)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Schizosaccharomyces pombe)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Dictyostelium discoideum)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Caenorhabditis elegans)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Drosophila melanogaster)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Gallus gallus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Xenopus tropicalis)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Bos taurus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Canis familiaris)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Rattus norvegicus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Mus musculus)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Homo sapiens)
Exosome Complex hydrolyzes mRNA by 3' to 5' exoribonuclease digestion (Sus scrofa)
5' to 3' Exoribonuclease Digestion of Decapped mRNA (yeast) (Saccharomyces cerevisiae)
5' to 3' exoribonuclease hydrolyzes decapped mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Gallus gallus)
CCR4-NOT complex deadenylates mRNA (Xenopus tropicalis)
CCR4-NOT complex deadenylates mRNA (Bos taurus)
CCR4-NOT complex deadenylates mRNA (Canis familiaris)
CCR4-NOT complex deadenylates mRNA (Mus musculus)
CCR4-NOT complex deadenylates mRNA (Homo sapiens)
CCR4-NOT complex deadenylates mRNA (Sus scrofa)
PARN deadenylates mRNA (Gallus gallus)
PARN deadenylates mRNA (Xenopus tropicalis)
PARN deadenylates mRNA (Bos taurus)
PARN deadenylates mRNA (Canis familiaris)
PARN deadenylates mRNA (Mus musculus)
PARN deadenylates mRNA (Homo sapiens)
PAN2-PAN3 complex partially deadenylates mRNA (Saccharomyces cerevisiae)
PAN2-PAN3 complex partially deadenylates mRNA (Gallus gallus)
PAN2-PAN3 complex partially deadenylates mRNA (Bos taurus)
PAN2-PAN3 complex partially deadenylates mRNA (Canis familiaris)
PAN2-PAN3 complex partially deadenylates mRNA (Rattus norvegicus)
PAN2-PAN3 complex partially deadenylates mRNA (Mus musculus)
PAN2-PAN3 complex partially deadenylates mRNA (Homo sapiens)
PAN2-PAN3 complex partially deadenylates mRNA (Sus scrofa)
PARN deadenylates mRNA (Sus scrofa)
p-S295-PDE3B hydrolyses cAMP to AMP (Plasmodium falciparum)
p-S295-PDE3B hydrolyses cAMP to AMP (Dictyostelium discoideum)
p-S295-PDE3B hydrolyses cAMP to AMP (Caenorhabditis elegans)
p-S295-PDE3B hydrolyses cAMP to AMP (Xenopus tropicalis)
p-S295-PDE3B hydrolyses cAMP to AMP (Sus scrofa)
p-S295-PDE3B hydrolyses cAMP to AMP (Bos taurus)
p-S295-PDE3B hydrolyses cAMP to AMP (Canis familiaris)
p-S295-PDE3B hydrolyses cAMP to AMP (Rattus norvegicus)
p-S295-PDE3B hydrolyses cAMP to AMP (Mus musculus)
p-S295-PDE3B hydrolyses cAMP to AMP (Homo sapiens)
p-S295-PDE3B hydrolyses cAMP to AMP (Gallus gallus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Sus scrofa)
K63polyUb-TRAF6 ubiquitinates TAK1 (Mus musculus)
K63polyUb-TRAF6 ubiquitinates TAK1 (Homo sapiens)
TRAF6 oligomer autoubiquitinates (Sus scrofa)
TRAF6 oligomer autoubiquitinates (Mus musculus)
TRAF6 oligomer autoubiquitinates (Homo sapiens)
TRAF6 oligomer autoubiquitinates (Canis familiaris)
K63polyUb-TRAF6 ubiquitinates TAK1 (Canis familiaris)
Auto-ubiquitination of TRAF6 (Sus scrofa)
Auto-ubiquitination of TRAF6 (Mus musculus)
Auto-ubiquitination of TRAF6 (Homo sapiens)
Auto-ubiquitination of TRAF6 (Canis familiaris)
cAMP hydrolysis by Cam-PDE 1 (Plasmodium falciparum)
cAMP hydrolysis by Cam-PDE 1 (Dictyostelium discoideum)
cAMP hydrolysis by Cam-PDE 1 (Caenorhabditis elegans)
cAMP hydrolysis by Cam-PDE 1 (Drosophila melanogaster)
cAMP hydrolysis by Cam-PDE 1 (Gallus gallus)
cAMP hydrolysis by Cam-PDE 1 (Xenopus tropicalis)
cAMP hydrolysis by Cam-PDE 1 (Sus scrofa)
cAMP hydrolysis by Cam-PDE 1 (Bos taurus)
cAMP hydrolysis by Cam-PDE 1 (Canis familiaris)
cAMP hydrolysis by Cam-PDE 1 (Rattus norvegicus)
cAMP hydrolysis by Cam-PDE 1 (Mus musculus)
cAMP hydrolysis by Cam-PDE 1 (Homo sapiens)
ISGylation of BECN1 (Homo sapiens)
ISGylation of IRF3 (Sus scrofa)
ISGylation of IRF3 (Bos taurus)
ISGylation of IRF3 (Rattus norvegicus)
ISGylation of IRF3 (Mus musculus)
Activation of ISG15 by UBA7 E1 ligase (Plasmodium falciparum)
Activation of ISG15 by UBA7 E1 ligase (Dictyostelium discoideum)
Activation of ISG15 by UBA7 E1 ligase (Caenorhabditis elegans)
Activation of ISG15 by UBA7 E1 ligase (Drosophila melanogaster)
Activation of ISG15 by UBA7 E1 ligase (Sus scrofa)
Activation of ISG15 by UBA7 E1 ligase (Bos taurus)
Activation of ISG15 by UBA7 E1 ligase (Canis familiaris)
Activation of ISG15 by UBA7 E1 ligase (Rattus norvegicus)
Activation of ISG15 by UBA7 E1 ligase (Mus musculus)
Activation of ISG15 by UBA7 E1 ligase (Homo sapiens)
ISGylation of IRF3 (Homo sapiens)
Polyubiquitination of substrate (Plasmodium falciparum)
Polyubiquitination of substrate (Saccharomyces cerevisiae)
Polyubiquitination of substrate (Schizosaccharomyces pombe)
Polyubiquitination of substrate (Dictyostelium discoideum)
Polyubiquitination of substrate (Caenorhabditis elegans)
Polyubiquitination of substrate (Drosophila melanogaster)
Polyubiquitination of substrate (Gallus gallus)
Polyubiquitination of substrate (Xenopus tropicalis)
Polyubiquitination of substrate (Danio rerio)
Polyubiquitination of substrate (Sus scrofa)
Polyubiquitination of substrate (Bos taurus)
Polyubiquitination of substrate (Canis familiaris)
Polyubiquitination of substrate (Rattus norvegicus)
Polyubiquitination of substrate (Mus musculus)
Transfer of Ub from E2 to substrate and release of E2 (Plasmodium falciparum)
Transfer of Ub from E2 to substrate and release of E2 (Saccharomyces cerevisiae)
Transfer of Ub from E2 to substrate and release of E2 (Schizosaccharomyces pombe)
Transfer of Ub from E2 to substrate and release of E2 (Dictyostelium discoideum)
Transfer of Ub from E2 to substrate and release of E2 (Caenorhabditis elegans)
Transfer of Ub from E2 to substrate and release of E2 (Drosophila melanogaster)
Transfer of Ub from E2 to substrate and release of E2 (Gallus gallus)
Transfer of Ub from E2 to substrate and release of E2 (Xenopus tropicalis)
Transfer of Ub from E2 to substrate and release of E2 (Danio rerio)
Transfer of Ub from E2 to substrate and release of E2 (Sus scrofa)
Transfer of Ub from E2 to substrate and release of E2 (Bos taurus)
Transfer of Ub from E2 to substrate and release of E2 (Canis familiaris)
Transfer of Ub from E2 to substrate and release of E2 (Rattus norvegicus)
Transfer of Ub from E2 to substrate and release of E2 (Mus musculus)
E1 mediated ubiquitin activation (Plasmodium falciparum)
E1 mediated ubiquitin activation (Saccharomyces cerevisiae)
E1 mediated ubiquitin activation (Schizosaccharomyces pombe)
E1 mediated ubiquitin activation (Dictyostelium discoideum)
E1 mediated ubiquitin activation (Caenorhabditis elegans)
E1 mediated ubiquitin activation (Drosophila melanogaster)
E1 mediated ubiquitin activation (Gallus gallus)
E1 mediated ubiquitin activation (Xenopus tropicalis)
E1 mediated ubiquitin activation (Danio rerio)
E1 mediated ubiquitin activation (Sus scrofa)
E1 mediated ubiquitin activation (Bos taurus)
E1 mediated ubiquitin activation (Canis familiaris)
E1 mediated ubiquitin activation (Rattus norvegicus)
E1 mediated ubiquitin activation (Mus musculus)
E1 mediated ubiquitin activation (Homo sapiens)
Transfer of Ub from E2 to substrate and release of E2 (Homo sapiens)
Polyubiquitination of substrate (Homo sapiens)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Gallus gallus)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Sus scrofa)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Bos taurus)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Canis familiaris)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Homo sapiens)
ASS1 tetramer:NMRAL1 dimer:NADPH transforms L-Asp and L-Cit to ARSUA (Mus musculus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Plasmodium falciparum)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Saccharomyces cerevisiae)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Schizosaccharomyces pombe)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Dictyostelium discoideum)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Caenorhabditis elegans)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Gallus gallus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Xenopus tropicalis)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Sus scrofa)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Bos taurus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Canis familiaris)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Rattus norvegicus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Mus musculus)
aspartate + glutamine + ATP <=> asparagine + glutamate + AMP + pyrophosphate [ASNS] (Homo sapiens)
ADPGK:Mg2+ phosphorylates Glc to G6P (Homo sapiens)
ADPGK:Mg2+ phosphorylates Glc to G6P (Mus musculus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Rattus norvegicus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Canis familiaris)
ADPGK:Mg2+ phosphorylates Glc to G6P (Bos taurus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Sus scrofa)
ADPGK:Mg2+ phosphorylates Glc to G6P (Danio rerio)
ADPGK:Mg2+ phosphorylates Glc to G6P (Xenopus tropicalis)
ADPGK:Mg2+ phosphorylates Glc to G6P (Gallus gallus)
ADPGK:Mg2+ phosphorylates Glc to G6P (Caenorhabditis elegans)
ADPGK:Mg2+ phosphorylates Glc to G6P (Dictyostelium discoideum)
as a member of
(d)AMP, (d)GMP, (d)IMP [cytosol]
(d)NMPs [cytosol]
(d)AMP [cytosol]
as a repeated unit of
poly (A) tail [cytosol]
This entity regulates
Negatively
Formation of PPAT dimers
(Gallus gallus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Drosophila melanogaster)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Danio rerio)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Sus scrofa)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Bos taurus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Canis familiaris)
inosine 5'-monophosphate + L-aspartate + GTP => adenylosuccinate + guanosine 5'-diphosphate + orthophosphate
(Mus musculus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Saccharomyces cerevisiae)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Caenorhabditis elegans)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Gallus gallus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Xenopus tropicalis)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Rattus norvegicus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Mus musculus)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Schizosaccharomyces pombe)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Dictyostelium discoideum)
FBP tetramers hydrolyze F1,6PP to Fru(6)P
(Homo sapiens)
Positively
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Gallus gallus)
PFK tetramer phosphorylates Fru(6)P
(Saccharomyces cerevisiae)
PFK tetramer phosphorylates Fru(6)P
(Gallus gallus)
Activation of cytosolic AMPK by phosphorylation
(Gallus gallus)
Activation of cytosolic AMPK by phosphorylation
(Homo sapiens)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Danio rerio)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Canis familiaris)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Mus musculus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Homo sapiens)
PFK tetramer phosphorylates Fru(6)P
(Schizosaccharomyces pombe)
PFK tetramer phosphorylates Fru(6)P
(Danio rerio)
PFK tetramer phosphorylates Fru(6)P
(Canis familiaris)
PFK tetramer phosphorylates Fru(6)P
(Mus musculus)
Activation of cytosolic AMPK by phosphorylation
(Canis familiaris)
Activation of cytosolic AMPK by phosphorylation
(Mus musculus)
Formation of PPAT tetramers
(Gallus gallus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Caenorhabditis elegans)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Drosophila melanogaster)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Sus scrofa)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Rattus norvegicus)
PFK tetramer phosphorylates Fru(6)P
(Caenorhabditis elegans)
PFK tetramer phosphorylates Fru(6)P
(Drosophila melanogaster)
PFK tetramer phosphorylates Fru(6)P
(Sus scrofa)
PFK tetramer phosphorylates Fru(6)P
(Rattus norvegicus)
Activation of cytosolic AMPK by phosphorylation
(Sus scrofa)
Activation of cytosolic AMPK by phosphorylation
(Rattus norvegicus)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Xenopus tropicalis)
Formation of phosphoribosyl pyrophosphate amidotransferase tetramer
(Bos taurus)
PFK tetramer phosphorylates Fru(6)P
(Bos taurus)
PFK tetramer phosphorylates Fru(6)P
(Homo sapiens)
Activation of cytosolic AMPK by phosphorylation
(Bos taurus)
Other forms of this molecule
adenosine 5'-monophosphate [endoplasmic reticulum membrane]
adenosine 5'-monophosphate [Golgi lumen]
AMP [extracellular region]
AMP [mitochondrial matrix]
AMP [peroxisomal matrix]
AMP [nucleoplasm]
Cross References
COMPOUND
C00020
ZINC
ZINC000003860156
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