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Gua [cytosol]
Stable Identifier
R-ALL-83956
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
2-amino-6-hydroxypurine, guanine
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
DNPH1 hydrolyses dGMP (Bos taurus)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Bos taurus)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Bos taurus)
Gua [cytosol]
Nucleotide salvage (Bos taurus)
Purine salvage (Bos taurus)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Bos taurus)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)
Gua [cytosol]
Transport of small molecules (Bos taurus)
SLC-mediated transmembrane transport (Bos taurus)
Transport of vitamins, nucleosides, and related molecules (Bos taurus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Bos taurus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Bos taurus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Nucleotide catabolism (Caenorhabditis elegans)
Purine catabolism (Caenorhabditis elegans)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Caenorhabditis elegans)
Gua [cytosol]
Nucleotide salvage (Caenorhabditis elegans)
Purine salvage (Caenorhabditis elegans)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Caenorhabditis elegans)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Caenorhabditis elegans)
Gua [cytosol]
Transport of small molecules (Caenorhabditis elegans)
SLC-mediated transmembrane transport (Caenorhabditis elegans)
Transport of vitamins, nucleosides, and related molecules (Caenorhabditis elegans)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Caenorhabditis elegans)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Caenorhabditis elegans)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
DNPH1 hydrolyses dGMP (Canis familiaris)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Canis familiaris)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Canis familiaris)
Gua [cytosol]
Nucleotide salvage (Canis familiaris)
Purine salvage (Canis familiaris)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Canis familiaris)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Canis familiaris)
Gua [cytosol]
Transport of small molecules (Canis familiaris)
SLC-mediated transmembrane transport (Canis familiaris)
Transport of vitamins, nucleosides, and related molecules (Canis familiaris)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Canis familiaris)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Canis familiaris)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
DNPH1 hydrolyses dGMP (Danio rerio)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Danio rerio)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Danio rerio)
Gua [cytosol]
Nucleotide salvage (Danio rerio)
Purine salvage (Danio rerio)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Danio rerio)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Danio rerio)
Gua [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of nucleotides (Dictyostelium discoideum)
Nucleotide catabolism (Dictyostelium discoideum)
Purine catabolism (Dictyostelium discoideum)
Guanine + H2O => Xanthine + NH4+ (Dictyostelium discoideum)
Gua [cytosol]
Nucleotide salvage (Dictyostelium discoideum)
Purine salvage (Dictyostelium discoideum)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Dictyostelium discoideum)
Gua, Hyp [cytosol]
Gua [cytosol]
Transport of small molecules (Dictyostelium discoideum)
SLC-mediated transmembrane transport (Dictyostelium discoideum)
Transport of vitamins, nucleosides, and related molecules (Dictyostelium discoideum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Dictyostelium discoideum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Dictyostelium discoideum)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Nucleotide catabolism (Drosophila melanogaster)
Purine catabolism (Drosophila melanogaster)
Guanine + H2O => Xanthine + NH4+ (Drosophila melanogaster)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Drosophila melanogaster)
Gua [cytosol]
Nucleotide salvage (Drosophila melanogaster)
Purine salvage (Drosophila melanogaster)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Drosophila melanogaster)
Gua [cytosol]
Transport of small molecules (Drosophila melanogaster)
SLC-mediated transmembrane transport (Drosophila melanogaster)
Transport of vitamins, nucleosides, and related molecules (Drosophila melanogaster)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Drosophila melanogaster)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Drosophila melanogaster)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Gallus gallus)
Metabolism of nucleotides (Gallus gallus)
Nucleotide catabolism (Gallus gallus)
Purine catabolism (Gallus gallus)
Guanine + H2O => Xanthine + NH4+ (Gallus gallus)
Gua [cytosol]
Nucleotide salvage (Gallus gallus)
Purine salvage (Gallus gallus)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Gallus gallus)
Gua, Hyp [cytosol]
Gua [cytosol]
Disease (Homo sapiens)
Diseases of metabolism (Homo sapiens)
Diseases of nucleotide metabolism (Homo sapiens)
Nucleotide salvage defects (Homo sapiens)
Defective HPRT1 disrupts guanine and hypoxanthine salvage (Homo sapiens)
Defective HPRT1 does not convert guanine or hypoxanthine to GMP or IMP (Homo sapiens)
Gua, Hyp [cytosol]
Gua [cytosol]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
DNPH1 hydrolyses dGMP (Homo sapiens)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Homo sapiens)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Homo sapiens)
Gua [cytosol]
Nucleotide salvage (Homo sapiens)
Purine salvage (Homo sapiens)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Homo sapiens)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Homo sapiens)
Gua [cytosol]
Metabolism of RNA (Homo sapiens)
tRNA processing (Homo sapiens)
tRNA modification in the nucleus and cytosol (Homo sapiens)
QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) (Homo sapiens)
Gua [cytosol]
Transport of small molecules (Homo sapiens)
SLC-mediated transmembrane transport (Homo sapiens)
Transport of vitamins, nucleosides, and related molecules (Homo sapiens)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Homo sapiens)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Homo sapiens)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
DNPH1 hydrolyses dGMP (Mus musculus)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Mus musculus)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Mus musculus)
Gua [cytosol]
Nucleotide salvage (Mus musculus)
Purine salvage (Mus musculus)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Mus musculus)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Mus musculus)
Gua [cytosol]
Transport of small molecules (Mus musculus)
SLC-mediated transmembrane transport (Mus musculus)
Transport of vitamins, nucleosides, and related molecules (Mus musculus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Mus musculus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Mus musculus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Nucleotide salvage (Plasmodium falciparum)
Purine salvage (Plasmodium falciparum)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Plasmodium falciparum)
Gua, Hyp [cytosol]
Gua [cytosol]
Transport of small molecules (Plasmodium falciparum)
SLC-mediated transmembrane transport (Plasmodium falciparum)
Transport of vitamins, nucleosides, and related molecules (Plasmodium falciparum)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Plasmodium falciparum)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Plasmodium falciparum)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
DNPH1 hydrolyses dGMP (Rattus norvegicus)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Rattus norvegicus)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Rattus norvegicus)
Gua [cytosol]
Nucleotide salvage (Rattus norvegicus)
Purine salvage (Rattus norvegicus)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Rattus norvegicus)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Rattus norvegicus)
Gua [cytosol]
Transport of small molecules (Rattus norvegicus)
SLC-mediated transmembrane transport (Rattus norvegicus)
Transport of vitamins, nucleosides, and related molecules (Rattus norvegicus)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Rattus norvegicus)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Rattus norvegicus)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Nucleotide catabolism (Saccharomyces cerevisiae)
Purine catabolism (Saccharomyces cerevisiae)
Guanine + H2O => Xanthine + NH4+ (Saccharomyces cerevisiae)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Saccharomyces cerevisiae)
Gua [cytosol]
Nucleotide salvage (Saccharomyces cerevisiae)
Purine salvage (Saccharomyces cerevisiae)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Saccharomyces cerevisiae)
Gua [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Nucleotide catabolism (Schizosaccharomyces pombe)
Purine catabolism (Schizosaccharomyces pombe)
Guanine + H2O => Xanthine + NH4+ (Schizosaccharomyces pombe)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Schizosaccharomyces pombe)
Gua [cytosol]
Nucleotide salvage (Schizosaccharomyces pombe)
Purine salvage (Schizosaccharomyces pombe)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Schizosaccharomyces pombe)
Gua [cytosol]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
DNPH1 hydrolyses dGMP (Sus scrofa)
Gua [cytosol]
Guanine + H2O => Xanthine + NH4+ (Sus scrofa)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Sus scrofa)
Gua [cytosol]
Nucleotide salvage (Sus scrofa)
Purine salvage (Sus scrofa)
HPRT1 catalyzes the conversion of guanine or hypoxanthine to GMP or IMP (Sus scrofa)
Gua, Hyp [cytosol]
Gua [cytosol]
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Sus scrofa)
Gua [cytosol]
Transport of small molecules (Sus scrofa)
SLC-mediated transmembrane transport (Sus scrofa)
Transport of vitamins, nucleosides, and related molecules (Sus scrofa)
Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane (Sus scrofa)
Equilibrative transport (export) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Equilibrative transport (import) of nucleosides and free bases by solute carrier family 29 (nucleoside transporters), member 2 (Sus scrofa)
ligands of SLC29A2 [cytosol]
Gua [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Nucleotide catabolism (Xenopus tropicalis)
Purine catabolism (Xenopus tropicalis)
Guanine + H2O => Xanthine + NH4+ (Xenopus tropicalis)
Gua [cytosol]
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Xenopus tropicalis)
Gua [cytosol]
Nucleotide salvage (Xenopus tropicalis)
Purine salvage (Xenopus tropicalis)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Xenopus tropicalis)
Gua [cytosol]
External Reference Information
External Reference
guanine [ChEBI:16235]
Participates
as an input of
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Homo sapiens)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Mus musculus)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Rattus norvegicus)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Canis familiaris)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Bos taurus)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Sus scrofa)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Danio rerio)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Xenopus tropicalis)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Drosophila melanogaster)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Caenorhabditis elegans)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Schizosaccharomyces pombe)
PNP catalyzes the conversion of guanine and (deoxy)ribose to (deoxy)guanosine (Saccharomyces cerevisiae)
Guanine + H2O => Xanthine + NH4+ (Homo sapiens)
Guanine + H2O => Xanthine + NH4+ (Mus musculus)
Guanine + H2O => Xanthine + NH4+ (Rattus norvegicus)
Guanine + H2O => Xanthine + NH4+ (Canis familiaris)
Guanine + H2O => Xanthine + NH4+ (Bos taurus)
Guanine + H2O => Xanthine + NH4+ (Sus scrofa)
Guanine + H2O => Xanthine + NH4+ (Danio rerio)
Guanine + H2O => Xanthine + NH4+ (Xenopus tropicalis)
Guanine + H2O => Xanthine + NH4+ (Gallus gallus)
Guanine + H2O => Xanthine + NH4+ (Drosophila melanogaster)
Guanine + H2O => Xanthine + NH4+ (Dictyostelium discoideum)
Guanine + H2O => Xanthine + NH4+ (Schizosaccharomyces pombe)
Guanine + H2O => Xanthine + NH4+ (Saccharomyces cerevisiae)
as an output of
QTRT1:QTRTD1 exchange guanine for queuosine at guanosine-34 of tRNA(Tyr) (Homo sapiens)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Homo sapiens)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Mus musculus)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Rattus norvegicus)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Canis familiaris)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Bos taurus)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Sus scrofa)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Danio rerio)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Xenopus tropicalis)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Drosophila melanogaster)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Caenorhabditis elegans)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Schizosaccharomyces pombe)
PNP catalyzes the conversion of (deoxy)guanosine to guanine and (deoxy)ribose (Saccharomyces cerevisiae)
DNPH1 hydrolyses dGMP (Homo sapiens)
DNPH1 hydrolyses dGMP (Mus musculus)
DNPH1 hydrolyses dGMP (Rattus norvegicus)
DNPH1 hydrolyses dGMP (Canis familiaris)
DNPH1 hydrolyses dGMP (Bos taurus)
DNPH1 hydrolyses dGMP (Sus scrofa)
DNPH1 hydrolyses dGMP (Danio rerio)
as a member of
ligands of SLC29A2 [cytosol]
Gua, Hyp [cytosol]
Other forms of this molecule
Gua [extracellular region]
Cross References
Guide to Pharmacology - Ligands
4556
COMPOUND
C00242
PubChem Substance
8145637
HMDB Metabolite
HMDB0000132
ZINC
000000895129
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