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2HG [mitochondrial matrix]
Stable Identifier
R-ALL-879997
Type
Chemical Compound [SimpleEntity]
Compartment
mitochondrial matrix
Synonyms
(R)-2-hydroxyglutarate, (R)-2-hydroxyglutaric acid
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Aerobic respiration and respiratory electron transport (Bos taurus)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Bos taurus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Bos taurus)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Bos taurus)
2HG [mitochondrial matrix]
Metabolism (Caenorhabditis elegans)
Aerobic respiration and respiratory electron transport (Caenorhabditis elegans)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Caenorhabditis elegans)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Caenorhabditis elegans)
2HG [mitochondrial matrix]
Metabolism (Canis familiaris)
Aerobic respiration and respiratory electron transport (Canis familiaris)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Canis familiaris)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Canis familiaris)
2HG [mitochondrial matrix]
Metabolism (Danio rerio)
Aerobic respiration and respiratory electron transport (Danio rerio)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Danio rerio)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Danio rerio)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Danio rerio)
2HG [mitochondrial matrix]
Metabolism (Dictyostelium discoideum)
Aerobic respiration and respiratory electron transport (Dictyostelium discoideum)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Dictyostelium discoideum)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Dictyostelium discoideum)
2HG [mitochondrial matrix]
Metabolism (Drosophila melanogaster)
Aerobic respiration and respiratory electron transport (Drosophila melanogaster)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Drosophila melanogaster)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Drosophila melanogaster)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Drosophila melanogaster)
2HG [mitochondrial matrix]
Metabolism (Gallus gallus)
Aerobic respiration and respiratory electron transport (Gallus gallus)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Gallus gallus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Gallus gallus)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Gallus gallus)
2HG [mitochondrial matrix]
Metabolism (Homo sapiens)
Aerobic respiration and respiratory electron transport (Homo sapiens)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Homo sapiens)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Homo sapiens)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Homo sapiens)
2HG [mitochondrial matrix]
Metabolism (Mus musculus)
Aerobic respiration and respiratory electron transport (Mus musculus)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Mus musculus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Mus musculus)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)
2HG [mitochondrial matrix]
Metabolism (Rattus norvegicus)
Aerobic respiration and respiratory electron transport (Rattus norvegicus)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Rattus norvegicus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Rattus norvegicus)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Rattus norvegicus)
2HG [mitochondrial matrix]
Metabolism (Saccharomyces cerevisiae)
Aerobic respiration and respiratory electron transport (Saccharomyces cerevisiae)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Saccharomyces cerevisiae)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Saccharomyces cerevisiae)
2HG [mitochondrial matrix]
Metabolism (Schizosaccharomyces pombe)
Aerobic respiration and respiratory electron transport (Schizosaccharomyces pombe)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Schizosaccharomyces pombe)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Schizosaccharomyces pombe)
2HG [mitochondrial matrix]
Metabolism (Sus scrofa)
Aerobic respiration and respiratory electron transport (Sus scrofa)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Sus scrofa)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Sus scrofa)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Sus scrofa)
2HG [mitochondrial matrix]
Metabolism (Xenopus tropicalis)
Aerobic respiration and respiratory electron transport (Xenopus tropicalis)
Interconversion of 2-oxoglutarate and 2-hydroxyglutarate (Xenopus tropicalis)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)
2HG [mitochondrial matrix]
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)
2HG [mitochondrial matrix]
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)
2HG [mitochondrial matrix]
External Reference Information
External Reference
(R)-2-hydroxyglutaric acid [ChEBI:32796]
Participates
as an input of
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Saccharomyces cerevisiae)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Schizosaccharomyces pombe)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Drosophila melanogaster)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Gallus gallus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Xenopus tropicalis)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Danio rerio)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Sus scrofa)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Bos taurus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Canis familiaris)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Rattus norvegicus)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Homo sapiens)
(R)-2-hydroxyglutarate + FAD => 2-oxoglutarate + FADH2 (Mus musculus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Dictyostelium discoideum)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Caenorhabditis elegans)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Drosophila melanogaster)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Gallus gallus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Xenopus tropicalis)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Danio rerio)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Sus scrofa)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Bos taurus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Canis familiaris)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Rattus norvegicus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Mus musculus)
(R)-2-hydroxyglutarate + succinate semialdehyde <=> 2-oxoglutarate + 4-hydroxybutyrate (Homo sapiens)
as an output of
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Dictyostelium discoideum)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Caenorhabditis elegans)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Drosophila melanogaster)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Gallus gallus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Xenopus tropicalis)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Danio rerio)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Sus scrofa)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Bos taurus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Canis familiaris)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Rattus norvegicus)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Homo sapiens)
2-oxoglutarate + 4-hydroxybutyrate <=> (R)-2-hydroxyglutarate + succinate semialdehyde (Mus musculus)
Other forms of this molecule
2HG [cytosol]
Cross References
COMPOUND
C01087
HMDB Metabolite
HMDB0000606
ZINC
000000402968
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