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L-Dopa [extracellular region]
Stable Identifier
R-ALL-8851314
Type
Chemical Compound [SimpleEntity]
Compartment
extracellular region
Synonyms
Dopa, 3,4-Dihydroxy-L-phenylalanine
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Sus scrofa
Xenopus tropicalis
Expand all
Signal Transduction (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Bos taurus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Bos taurus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
L-Dopa [extracellular region]
GPCR ligand binding (Bos taurus)
Class A/1 (Rhodopsin-like receptors) (Bos taurus)
Amine ligand-binding receptors (Bos taurus)
GPR143 binds L-Dopa (Bos taurus)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Bos taurus)
L-Dopa [extracellular region]
Signal Transduction (Caenorhabditis elegans)
Signaling by GPCR (Caenorhabditis elegans)
GPCR downstream signalling (Caenorhabditis elegans)
G alpha (q) signalling events (Caenorhabditis elegans)
The Ligand:GPCR:Gq complex dissociates (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
L-Dopa [extracellular region]
Signal Transduction (Canis familiaris)
Signaling by GPCR (Canis familiaris)
GPCR downstream signalling (Canis familiaris)
G alpha (q) signalling events (Canis familiaris)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Canis familiaris)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
L-Dopa [extracellular region]
GPCR ligand binding (Canis familiaris)
Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
Amine ligand-binding receptors (Canis familiaris)
GPR143 binds L-Dopa (Canis familiaris)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
L-Dopa [extracellular region]
Signal Transduction (Drosophila melanogaster)
Signaling by GPCR (Drosophila melanogaster)
GPCR downstream signalling (Drosophila melanogaster)
G alpha (q) signalling events (Drosophila melanogaster)
The Ligand:GPCR:Gq complex dissociates (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
L-Dopa [extracellular region]
Signal Transduction (Gallus gallus)
Signaling by GPCR (Gallus gallus)
GPCR downstream signalling (Gallus gallus)
G alpha (q) signalling events (Gallus gallus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Gallus gallus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
L-Dopa [extracellular region]
GPCR ligand binding (Gallus gallus)
Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
Amine ligand-binding receptors (Gallus gallus)
GPR143 binds L-Dopa (Gallus gallus)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
L-Dopa [extracellular region]
Signal Transduction (Homo sapiens)
Signaling by GPCR (Homo sapiens)
GPCR downstream signalling (Homo sapiens)
G alpha (q) signalling events (Homo sapiens)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Homo sapiens)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Homo sapiens)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
L-Dopa [extracellular region]
GPCR ligand binding (Homo sapiens)
Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
Amine ligand-binding receptors (Homo sapiens)
GPR143 binds L-Dopa (Homo sapiens)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
L-Dopa [extracellular region]
Signal Transduction (Mus musculus)
Signaling by GPCR (Mus musculus)
GPCR downstream signalling (Mus musculus)
G alpha (q) signalling events (Mus musculus)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Mus musculus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Mus musculus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
L-Dopa [extracellular region]
GPCR ligand binding (Mus musculus)
Class A/1 (Rhodopsin-like receptors) (Mus musculus)
Amine ligand-binding receptors (Mus musculus)
GPR143 binds L-Dopa (Mus musculus)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Mus musculus)
L-Dopa [extracellular region]
Signal Transduction (Rattus norvegicus)
Signaling by GPCR (Rattus norvegicus)
GPCR downstream signalling (Rattus norvegicus)
G alpha (q) signalling events (Rattus norvegicus)
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
GPR143:L-Dopa [plasma membrane] (Rattus norvegicus)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Rattus norvegicus)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Rattus norvegicus)
GPR143:L-Dopa [plasma membrane] (Rattus norvegicus)
L-Dopa [extracellular region]
GPCR ligand binding (Rattus norvegicus)
Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
Amine ligand-binding receptors (Rattus norvegicus)
GPR143 binds L-Dopa (Rattus norvegicus)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Rattus norvegicus)
L-Dopa [extracellular region]
Signal Transduction (Sus scrofa)
Signaling by GPCR (Sus scrofa)
GPCR downstream signalling (Sus scrofa)
G alpha (q) signalling events (Sus scrofa)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
Liganded Gq/11-activating GPCRs act as GEFs for Gq/11 (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Sus scrofa)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
L-Dopa [extracellular region]
GPCR ligand binding (Sus scrofa)
Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
Amine ligand-binding receptors (Sus scrofa)
GPR143 binds L-Dopa (Sus scrofa)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
L-Dopa [extracellular region]
Signal Transduction (Xenopus tropicalis)
Signaling by GPCR (Xenopus tropicalis)
GPCR downstream signalling (Xenopus tropicalis)
G alpha (q) signalling events (Xenopus tropicalis)
Liganded Gq-activating GPCRs bind inactive heterotrimeric Gq (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
GPR143:L-Dopa [plasma membrane] (Xenopus tropicalis)
L-Dopa [extracellular region]
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (inactive) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
GPR143:L-Dopa [plasma membrane] (Xenopus tropicalis)
L-Dopa [extracellular region]
The Ligand:GPCR:Gq complex dissociates (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11:Heterotrimeric G-protein Gq (active) [plasma membrane] (Xenopus tropicalis)
Ligand:GPCR complexes that activate Gq/11 [plasma membrane] (Xenopus tropicalis)
GPR143:L-Dopa [plasma membrane] (Xenopus tropicalis)
L-Dopa [extracellular region]
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
L-Dopa [extracellular region]
GPCR ligand binding (Xenopus tropicalis)
Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
Amine ligand-binding receptors (Xenopus tropicalis)
GPR143 binds L-Dopa (Xenopus tropicalis)
L-Dopa [extracellular region]
GPR143:L-Dopa [plasma membrane] (Xenopus tropicalis)
L-Dopa [extracellular region]
External Reference Information
External Reference
L-dopa zwitterion [ChEBI:57504]
Participates
as an input of
GPR143 binds L-Dopa (Gallus gallus)
GPR143 binds L-Dopa (Xenopus tropicalis)
GPR143 binds L-Dopa (Sus scrofa)
GPR143 binds L-Dopa (Bos taurus)
GPR143 binds L-Dopa (Canis familiaris)
GPR143 binds L-Dopa (Rattus norvegicus)
GPR143 binds L-Dopa (Mus musculus)
GPR143 binds L-Dopa (Homo sapiens)
as a member of
Ligands of GPCRs that activate Gq/11 [extracellular region] (Sus scrofa)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Drosophila melanogaster)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Gallus gallus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Bos taurus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Canis familiaris)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Mus musculus)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Xenopus tropicalis)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Caenorhabditis elegans)
Ligands of GPCRs that activate Gq/11 [extracellular region] (Homo sapiens)
as a component of
GPR143:L-Dopa [plasma membrane] (Sus scrofa)
GPR143:L-Dopa [plasma membrane] (Rattus norvegicus)
GPR143:L-Dopa [plasma membrane] (Mus musculus)
GPR143:L-Dopa [plasma membrane] (Gallus gallus)
GPR143:L-Dopa [plasma membrane] (Canis familiaris)
GPR143:L-Dopa [plasma membrane] (Xenopus tropicalis)
GPR143:L-Dopa [plasma membrane] (Bos taurus)
GPR143:L-Dopa [plasma membrane] (Homo sapiens)
Other forms of this molecule
L-Dopa [melanosome lumen]
L-Dopa [cytosol]
Cross References
COMPOUND
C00355
ZINC
000000895199
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