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AP-DOBu [cytosol]
Stable Identifier
R-ALL-893615
Type
Chemical Compound [SimpleEntity]
Compartment
cytosol
Synonyms
4-(2-aminophenyl)-2,4-dioxobutanoic acid
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Metabolism (Bos taurus)
Metabolism of amino acids and derivatives (Bos taurus)
Tryptophan catabolism (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)
AP-DOBu [cytosol]
Metabolism (Caenorhabditis elegans)
Metabolism of amino acids and derivatives (Caenorhabditis elegans)
Tryptophan catabolism (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)
AP-DOBu [cytosol]
Metabolism (Canis familiaris)
Metabolism of amino acids and derivatives (Canis familiaris)
Tryptophan catabolism (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Canis familiaris)
AP-DOBu [cytosol]
Metabolism (Danio rerio)
Metabolism of amino acids and derivatives (Danio rerio)
Tryptophan catabolism (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Danio rerio)
AP-DOBu [cytosol]
Metabolism (Dictyostelium discoideum)
Metabolism of amino acids and derivatives (Dictyostelium discoideum)
Tryptophan catabolism (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)
AP-DOBu [cytosol]
Metabolism (Drosophila melanogaster)
Metabolism of amino acids and derivatives (Drosophila melanogaster)
Tryptophan catabolism (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)
AP-DOBu [cytosol]
Metabolism (Gallus gallus)
Metabolism of amino acids and derivatives (Gallus gallus)
Tryptophan catabolism (Gallus gallus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Gallus gallus)
AP-DOBu [cytosol]
Metabolism (Homo sapiens)
Metabolism of amino acids and derivatives (Homo sapiens)
Tryptophan catabolism (Homo sapiens)
4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] (Homo sapiens)
AP-DOBu [cytosol]
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Homo sapiens)
AP-DOBu [cytosol]
kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] (Homo sapiens)
AP-DOBu [cytosol]
Metabolism (Mus musculus)
Metabolism of amino acids and derivatives (Mus musculus)
Tryptophan catabolism (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Mus musculus)
AP-DOBu [cytosol]
Metabolism (Rattus norvegicus)
Metabolism of amino acids and derivatives (Rattus norvegicus)
Tryptophan catabolism (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)
AP-DOBu [cytosol]
Metabolism (Saccharomyces cerevisiae)
Metabolism of amino acids and derivatives (Saccharomyces cerevisiae)
Tryptophan catabolism (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)
AP-DOBu [cytosol]
Metabolism (Schizosaccharomyces pombe)
Metabolism of amino acids and derivatives (Schizosaccharomyces pombe)
Tryptophan catabolism (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)
AP-DOBu [cytosol]
Metabolism (Sus scrofa)
Metabolism of amino acids and derivatives (Sus scrofa)
Tryptophan catabolism (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Sus scrofa)
AP-DOBu [cytosol]
Metabolism (Xenopus tropicalis)
Metabolism of amino acids and derivatives (Xenopus tropicalis)
Tryptophan catabolism (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)
AP-DOBu [cytosol]
External Reference Information
External Reference
4-(2-aminophenyl)-2,4-dioxobutanoic acid [ChEBI:17442]
Participates
as an input of
4-(2-aminophenyl)-2,4-dioxobutanoate => kynurenic acid + H2O [cytosolic] (Homo sapiens)
as an output of
kynurenine + pyruvate => 4-(2-aminophenyl)-2,4-dioxobutanoic acid + alanine [CCBL2] (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Saccharomyces cerevisiae)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Schizosaccharomyces pombe)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Dictyostelium discoideum)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Caenorhabditis elegans)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Drosophila melanogaster)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Xenopus tropicalis)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Danio rerio)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Sus scrofa)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Bos taurus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Canis familiaris)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Rattus norvegicus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Mus musculus)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Homo sapiens)
PXLP-KYAT1 dimer transaminates L-KYN to AP-DOBu (Gallus gallus)
Other forms of this molecule
APDBA [mitochondrial matrix]
Cross References
COMPOUND
C01252
HMDB Metabolite
HMDB0000978
ZINC
000030724120
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