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About
What is Reactome ?
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Table of Contents
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Diseases
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H+ [nucleoplasm]
Stable Identifier
R-ALL-9668967
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
proton, hydron
Icon
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Caenorhabditis elegans
Canis familiaris
Danio rerio
Dictyostelium discoideum
Drosophila melanogaster
Gallus gallus
Mus musculus
Plasmodium falciparum
Rattus norvegicus
Saccharomyces cerevisiae
Schizosaccharomyces pombe
Sus scrofa
Xenopus tropicalis
Expand all
Cell Cycle (Bos taurus)
Chromosome Maintenance (Bos taurus)
Telomere Maintenance (Bos taurus)
Extension of Telomeres (Bos taurus)
Telomere C-strand (Lagging Strand) Synthesis (Bos taurus)
Processive synthesis on the C-strand of the telomere (Bos taurus)
Formation of the Flap Intermediate on the C-strand (Bos taurus)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Bos taurus)
Disassociation of Telomerase RNP and the Chromosome End (Bos taurus)
H+ [nucleoplasm]
Metabolism (Bos taurus)
Metabolism of nucleotides (Bos taurus)
Interconversion of nucleotide di- and triphosphates (Bos taurus)
dUTP + H2O => dUMP + pyrophosphate (Bos taurus)
H+ [nucleoplasm]
Nucleotide catabolism (Bos taurus)
Purine catabolism (Bos taurus)
Phosphate bond hydrolysis by NUDT proteins (Bos taurus)
NUDT16 hydrolyses IDP to IMP (Bos taurus)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Bos taurus)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Bos taurus)
H+ [nucleoplasm]
Metabolism (Caenorhabditis elegans)
Metabolism of nucleotides (Caenorhabditis elegans)
Interconversion of nucleotide di- and triphosphates (Caenorhabditis elegans)
dUTP + H2O => dUMP + pyrophosphate (Caenorhabditis elegans)
H+ [nucleoplasm]
Nucleotide catabolism (Caenorhabditis elegans)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Caenorhabditis elegans)
H+ [nucleoplasm]
Cell Cycle (Canis familiaris)
Chromosome Maintenance (Canis familiaris)
Telomere Maintenance (Canis familiaris)
Extension of Telomeres (Canis familiaris)
Telomere C-strand (Lagging Strand) Synthesis (Canis familiaris)
Processive synthesis on the C-strand of the telomere (Canis familiaris)
Formation of the Flap Intermediate on the C-strand (Canis familiaris)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Canis familiaris)
Disassociation of Telomerase RNP and the Chromosome End (Canis familiaris)
H+ [nucleoplasm]
Metabolism (Canis familiaris)
Metabolism of nucleotides (Canis familiaris)
Interconversion of nucleotide di- and triphosphates (Canis familiaris)
dUTP + H2O => dUMP + pyrophosphate (Canis familiaris)
H+ [nucleoplasm]
Nucleotide catabolism (Canis familiaris)
Purine catabolism (Canis familiaris)
Phosphate bond hydrolysis by NUDT proteins (Canis familiaris)
NUDT16 hydrolyses IDP to IMP (Canis familiaris)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Canis familiaris)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Canis familiaris)
H+ [nucleoplasm]
Cell Cycle (Danio rerio)
Chromosome Maintenance (Danio rerio)
Telomere Maintenance (Danio rerio)
Extension of Telomeres (Danio rerio)
Telomere C-strand (Lagging Strand) Synthesis (Danio rerio)
Processive synthesis on the C-strand of the telomere (Danio rerio)
Formation of the Flap Intermediate on the C-strand (Danio rerio)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Danio rerio)
Disassociation of Telomerase RNP and the Chromosome End (Danio rerio)
H+ [nucleoplasm]
Metabolism (Danio rerio)
Metabolism of nucleotides (Danio rerio)
Interconversion of nucleotide di- and triphosphates (Danio rerio)
dUTP + H2O => dUMP + pyrophosphate (Danio rerio)
H+ [nucleoplasm]
Nucleotide catabolism (Danio rerio)
Purine catabolism (Danio rerio)
Phosphate bond hydrolysis by NUDT proteins (Danio rerio)
NUDT16 hydrolyses IDP to IMP (Danio rerio)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Danio rerio)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Danio rerio)
H+ [nucleoplasm]
Metabolism (Dictyostelium discoideum)
Metabolism of nucleotides (Dictyostelium discoideum)
Interconversion of nucleotide di- and triphosphates (Dictyostelium discoideum)
dUTP + H2O => dUMP + pyrophosphate (Dictyostelium discoideum)
H+ [nucleoplasm]
Nucleotide catabolism (Dictyostelium discoideum)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Dictyostelium discoideum)
H+ [nucleoplasm]
Metabolism (Drosophila melanogaster)
Metabolism of nucleotides (Drosophila melanogaster)
Interconversion of nucleotide di- and triphosphates (Drosophila melanogaster)
dUTP + H2O => dUMP + pyrophosphate (Drosophila melanogaster)
H+ [nucleoplasm]
Nucleotide catabolism (Drosophila melanogaster)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Drosophila melanogaster)
H+ [nucleoplasm]
Metabolism (Gallus gallus)
Metabolism of nucleotides (Gallus gallus)
Interconversion of nucleotide di- and triphosphates (Gallus gallus)
dUTP + H2O => dUMP + pyrophosphate (Gallus gallus)
H+ [nucleoplasm]
Nucleotide catabolism (Gallus gallus)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Gallus gallus)
H+ [nucleoplasm]
Cell Cycle (Homo sapiens)
Chromosome Maintenance (Homo sapiens)
Telomere Maintenance (Homo sapiens)
Extension of Telomeres (Homo sapiens)
Telomere C-strand (Lagging Strand) Synthesis (Homo sapiens)
Processive synthesis on the C-strand of the telomere (Homo sapiens)
Formation of the Flap Intermediate on the C-strand (Homo sapiens)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Homo sapiens)
Disassociation of Telomerase RNP and the Chromosome End (Homo sapiens)
H+ [nucleoplasm]
Developmental Biology (Homo sapiens)
Maternal to zygotic transition (MZT) (Homo sapiens)
Chromatin modifications during the maternal to zygotic transition (MZT) (Homo sapiens)
AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine (Homo sapiens)
H+ [nucleoplasm]
Replacement of protamines by nucleosomes in the male pronucleus (Homo sapiens)
METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) (Homo sapiens)
H+ [nucleoplasm]
Metabolism (Homo sapiens)
Metabolism of nucleotides (Homo sapiens)
Interconversion of nucleotide di- and triphosphates (Homo sapiens)
dUTP + H2O => dUMP + pyrophosphate (Homo sapiens)
H+ [nucleoplasm]
Nucleotide catabolism (Homo sapiens)
Purine catabolism (Homo sapiens)
Phosphate bond hydrolysis by NUDT proteins (Homo sapiens)
NUDT16 hydrolyses IDP to IMP (Homo sapiens)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Homo sapiens)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Homo sapiens)
H+ [nucleoplasm]
Cell Cycle (Mus musculus)
Chromosome Maintenance (Mus musculus)
Telomere Maintenance (Mus musculus)
Extension of Telomeres (Mus musculus)
Telomere C-strand (Lagging Strand) Synthesis (Mus musculus)
Processive synthesis on the C-strand of the telomere (Mus musculus)
Formation of the Flap Intermediate on the C-strand (Mus musculus)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Mus musculus)
Disassociation of Telomerase RNP and the Chromosome End (Mus musculus)
H+ [nucleoplasm]
Metabolism (Mus musculus)
Metabolism of nucleotides (Mus musculus)
Interconversion of nucleotide di- and triphosphates (Mus musculus)
dUTP + H2O => dUMP + pyrophosphate (Mus musculus)
H+ [nucleoplasm]
Nucleotide catabolism (Mus musculus)
Purine catabolism (Mus musculus)
Phosphate bond hydrolysis by NUDT proteins (Mus musculus)
NUDT16 hydrolyses IDP to IMP (Mus musculus)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Mus musculus)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Mus musculus)
H+ [nucleoplasm]
Metabolism (Plasmodium falciparum)
Metabolism of nucleotides (Plasmodium falciparum)
Interconversion of nucleotide di- and triphosphates (Plasmodium falciparum)
dUTP + H2O => dUMP + pyrophosphate (Plasmodium falciparum)
H+ [nucleoplasm]
Nucleotide catabolism (Plasmodium falciparum)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Plasmodium falciparum)
H+ [nucleoplasm]
Cell Cycle (Rattus norvegicus)
Chromosome Maintenance (Rattus norvegicus)
Telomere Maintenance (Rattus norvegicus)
Extension of Telomeres (Rattus norvegicus)
Telomere C-strand (Lagging Strand) Synthesis (Rattus norvegicus)
Processive synthesis on the C-strand of the telomere (Rattus norvegicus)
Formation of the Flap Intermediate on the C-strand (Rattus norvegicus)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Rattus norvegicus)
Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)
H+ [nucleoplasm]
Metabolism (Rattus norvegicus)
Metabolism of nucleotides (Rattus norvegicus)
Interconversion of nucleotide di- and triphosphates (Rattus norvegicus)
dUTP + H2O => dUMP + pyrophosphate (Rattus norvegicus)
H+ [nucleoplasm]
Nucleotide catabolism (Rattus norvegicus)
Purine catabolism (Rattus norvegicus)
Phosphate bond hydrolysis by NUDT proteins (Rattus norvegicus)
NUDT16 hydrolyses IDP to IMP (Rattus norvegicus)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Rattus norvegicus)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)
H+ [nucleoplasm]
Metabolism (Saccharomyces cerevisiae)
Metabolism of nucleotides (Saccharomyces cerevisiae)
Interconversion of nucleotide di- and triphosphates (Saccharomyces cerevisiae)
dUTP + H2O => dUMP + pyrophosphate (Saccharomyces cerevisiae)
H+ [nucleoplasm]
Metabolism (Schizosaccharomyces pombe)
Metabolism of nucleotides (Schizosaccharomyces pombe)
Interconversion of nucleotide di- and triphosphates (Schizosaccharomyces pombe)
dUTP + H2O => dUMP + pyrophosphate (Schizosaccharomyces pombe)
H+ [nucleoplasm]
Cell Cycle (Sus scrofa)
Chromosome Maintenance (Sus scrofa)
Telomere Maintenance (Sus scrofa)
Extension of Telomeres (Sus scrofa)
Telomere C-strand (Lagging Strand) Synthesis (Sus scrofa)
Processive synthesis on the C-strand of the telomere (Sus scrofa)
Formation of the Flap Intermediate on the C-strand (Sus scrofa)
H+ [nucleoplasm]
Telomere Extension By Telomerase (Sus scrofa)
Disassociation of Telomerase RNP and the Chromosome End (Sus scrofa)
H+ [nucleoplasm]
Metabolism (Sus scrofa)
Metabolism of nucleotides (Sus scrofa)
Interconversion of nucleotide di- and triphosphates (Sus scrofa)
dUTP + H2O => dUMP + pyrophosphate (Sus scrofa)
H+ [nucleoplasm]
Nucleotide catabolism (Sus scrofa)
Purine catabolism (Sus scrofa)
Phosphate bond hydrolysis by NUDT proteins (Sus scrofa)
NUDT16 hydrolyses IDP to IMP (Sus scrofa)
H+ [nucleoplasm]
NUDT16 hydrolyses dIDP to dIMP (Sus scrofa)
H+ [nucleoplasm]
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Sus scrofa)
H+ [nucleoplasm]
Cell Cycle (Xenopus tropicalis)
Chromosome Maintenance (Xenopus tropicalis)
Telomere Maintenance (Xenopus tropicalis)
Extension of Telomeres (Xenopus tropicalis)
Telomere C-strand (Lagging Strand) Synthesis (Xenopus tropicalis)
Processive synthesis on the C-strand of the telomere (Xenopus tropicalis)
Formation of the Flap Intermediate on the C-strand (Xenopus tropicalis)
H+ [nucleoplasm]
Metabolism (Xenopus tropicalis)
Metabolism of nucleotides (Xenopus tropicalis)
Interconversion of nucleotide di- and triphosphates (Xenopus tropicalis)
dUTP + H2O => dUMP + pyrophosphate (Xenopus tropicalis)
H+ [nucleoplasm]
Nucleotide catabolism (Xenopus tropicalis)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Xenopus tropicalis)
H+ [nucleoplasm]
External Reference Information
External Reference
hydron [ChEBI:15378]
Participates
as an input of
AICDA deaminates cytidine in chromatin containing histone H3.3 and 5-methylcytidine (Homo sapiens)
as an output of
Mettl23 dimethylates histone H3.3 arginine-18 (arginine-17 in the mature protein) (Mus musculus)
METTL23 dimethylates histone H3.3 arginine-17 (arginine-18 in the preprotein) (Homo sapiens)
dUTP + H2O => dUMP + pyrophosphate (Plasmodium falciparum)
dUTP + H2O => dUMP + pyrophosphate (Saccharomyces cerevisiae)
dUTP + H2O => dUMP + pyrophosphate (Schizosaccharomyces pombe)
dUTP + H2O => dUMP + pyrophosphate (Dictyostelium discoideum)
dUTP + H2O => dUMP + pyrophosphate (Caenorhabditis elegans)
dUTP + H2O => dUMP + pyrophosphate (Drosophila melanogaster)
dUTP + H2O => dUMP + pyrophosphate (Gallus gallus)
dUTP + H2O => dUMP + pyrophosphate (Xenopus tropicalis)
dUTP + H2O => dUMP + pyrophosphate (Sus scrofa)
dUTP + H2O => dUMP + pyrophosphate (Bos taurus)
dUTP + H2O => dUMP + pyrophosphate (Canis familiaris)
Formation of the Flap Intermediate on the C-strand (Homo sapiens)
Disassociation of Telomerase RNP and the Chromosome End (Homo sapiens)
Disassociation of Telomerase RNP and the Chromosome End (Mus musculus)
Disassociation of Telomerase RNP and the Chromosome End (Rattus norvegicus)
Disassociation of Telomerase RNP and the Chromosome End (Canis familiaris)
Disassociation of Telomerase RNP and the Chromosome End (Bos taurus)
Disassociation of Telomerase RNP and the Chromosome End (Sus scrofa)
Disassociation of Telomerase RNP and the Chromosome End (Danio rerio)
Formation of the Flap Intermediate on the C-strand (Mus musculus)
Formation of the Flap Intermediate on the C-strand (Rattus norvegicus)
Formation of the Flap Intermediate on the C-strand (Canis familiaris)
Formation of the Flap Intermediate on the C-strand (Bos taurus)
Formation of the Flap Intermediate on the C-strand (Sus scrofa)
Formation of the Flap Intermediate on the C-strand (Danio rerio)
Formation of the Flap Intermediate on the C-strand (Xenopus tropicalis)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Danio rerio)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Homo sapiens)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Mus musculus)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Rattus norvegicus)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Canis familiaris)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Bos taurus)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Sus scrofa)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Xenopus tropicalis)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Gallus gallus)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Drosophila melanogaster)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Caenorhabditis elegans)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Dictyostelium discoideum)
SAMHD1:Zn2+ tetramer hydrolyzes dNTP to nucleoside and triphosphate (Plasmodium falciparum)
NUDT16 hydrolyses IDP to IMP (Danio rerio)
NUDT16 hydrolyses IDP to IMP (Homo sapiens)
NUDT16 hydrolyses IDP to IMP (Mus musculus)
NUDT16 hydrolyses IDP to IMP (Rattus norvegicus)
NUDT16 hydrolyses IDP to IMP (Canis familiaris)
NUDT16 hydrolyses IDP to IMP (Bos taurus)
NUDT16 hydrolyses IDP to IMP (Sus scrofa)
NUDT16 hydrolyses dIDP to dIMP (Danio rerio)
NUDT16 hydrolyses dIDP to dIMP (Homo sapiens)
NUDT16 hydrolyses dIDP to dIMP (Mus musculus)
NUDT16 hydrolyses dIDP to dIMP (Rattus norvegicus)
NUDT16 hydrolyses dIDP to dIMP (Canis familiaris)
NUDT16 hydrolyses dIDP to dIMP (Bos taurus)
NUDT16 hydrolyses dIDP to dIMP (Sus scrofa)
dUTP + H2O => dUMP + pyrophosphate (Danio rerio)
dUTP + H2O => dUMP + pyrophosphate (Homo sapiens)
dUTP + H2O => dUMP + pyrophosphate (Mus musculus)
dUTP + H2O => dUMP + pyrophosphate (Rattus norvegicus)
Other forms of this molecule
H+ [early endosome]
H+ [synaptic vesicle lumen]
H+ [platelet dense tubular network lumen]
H+ [sperm flagellum]
H+ [synaptic vesicle]
H+ [late endosome lumen]
H+ [early endosome lumen]
H+ [phagolysosome]
H+ [cytoplasm]
H+ [clathrin-sculpted acetylcholine transport vesicle lumen]
H+ [phagocytic vesicle lumen]
H+ [melanosome lumen]
H+ [mitochondrial inner membrane]
H+ [nuclear envelope]
H+ [endocytic vesicle lumen]
H+ [Golgi lumen]
H+ [lysosomal lumen]
H+ [peroxisomal matrix]
H+ [endolysosome lumen]
H+ [endoplasmic reticulum lumen]
H+ [endoplasmic reticulum-Golgi intermediate compartment]
H+ [endosome lumen]
H+ [extracellular region]
H+ [clathrin-sculpted monoamine transport vesicle lumen]
H+ [mitochondrial intermembrane space]
H+ [mitochondrial matrix]
H+ [cytosol]
Cross References
COMPOUND
C00080
PubChem Substance
8145820
HMDB Metabolite
HMDB0059597
© 2023
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![H+ [nucleoplasm] icon](/icon/R-ICO-012841.svg){kind=icon}
