Reactome | lixivaptan [extracellular region]

lixivaptan [extracellular region]

Stable Identifier

R-ALL-9703935

Type

ChemicalDrug

Compartment

extracellular region

Locations in the PathwayBrowser

for Species:

Expand all

Signal Transduction (Bos taurus)

- Signaling by GPCR (Bos taurus)
  - GPCR ligand binding (Bos taurus)
    - Class A/1 (Rhodopsin-like receptors) (Bos taurus)
      - Peptide ligand-binding receptors (Bos taurus)
        
        Vasopressin-like receptors (Bos taurus)
        
        AVPR1A,2 bind AVPR antagonists (Bos taurus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Bos taurus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Canis familiaris)

- Signaling by GPCR (Canis familiaris)
  - GPCR ligand binding (Canis familiaris)
    - Class A/1 (Rhodopsin-like receptors) (Canis familiaris)
      - Peptide ligand-binding receptors (Canis familiaris)
        
        Vasopressin-like receptors (Canis familiaris)
        
        AVPR1A,2 bind AVPR antagonists (Canis familiaris)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Canis familiaris)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Danio rerio)

- Signaling by GPCR (Danio rerio)
  - GPCR ligand binding (Danio rerio)
    - Class A/1 (Rhodopsin-like receptors) (Danio rerio)
      - Peptide ligand-binding receptors (Danio rerio)
        
        Vasopressin-like receptors (Danio rerio)
        
        AVPR1A,2 bind AVPR antagonists (Danio rerio)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Danio rerio)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Gallus gallus)

- Signaling by GPCR (Gallus gallus)
  - GPCR ligand binding (Gallus gallus)
    - Class A/1 (Rhodopsin-like receptors) (Gallus gallus)
      - Peptide ligand-binding receptors (Gallus gallus)
        
        Vasopressin-like receptors (Gallus gallus)
        
        AVPR1A,2 bind AVPR antagonists (Gallus gallus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Gallus gallus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Homo sapiens)

- Signaling by GPCR (Homo sapiens)
  - GPCR ligand binding (Homo sapiens)
    - Class A/1 (Rhodopsin-like receptors) (Homo sapiens)
      - Peptide ligand-binding receptors (Homo sapiens)
        
        Vasopressin-like receptors (Homo sapiens)
        
        AVPR1A,2 bind AVPR antagonists (Homo sapiens)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Homo sapiens)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Mus musculus)

- Signaling by GPCR (Mus musculus)
  - GPCR ligand binding (Mus musculus)
    - Class A/1 (Rhodopsin-like receptors) (Mus musculus)
      - Peptide ligand-binding receptors (Mus musculus)
        
        Vasopressin-like receptors (Mus musculus)
        
        AVPR1A,2 bind AVPR antagonists (Mus musculus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Mus musculus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Rattus norvegicus)

- Signaling by GPCR (Rattus norvegicus)
  - GPCR ligand binding (Rattus norvegicus)
    - Class A/1 (Rhodopsin-like receptors) (Rattus norvegicus)
      - Peptide ligand-binding receptors (Rattus norvegicus)
        
        Vasopressin-like receptors (Rattus norvegicus)
        
        AVPR1A,2 bind AVPR antagonists (Rattus norvegicus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Rattus norvegicus)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Sus scrofa)

- Signaling by GPCR (Sus scrofa)
  - GPCR ligand binding (Sus scrofa)
    - Class A/1 (Rhodopsin-like receptors) (Sus scrofa)
      - Peptide ligand-binding receptors (Sus scrofa)
        
        Vasopressin-like receptors (Sus scrofa)
        
        AVPR1A,2 bind AVPR antagonists (Sus scrofa)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Sus scrofa)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

Signal Transduction (Xenopus tropicalis)

- Signaling by GPCR (Xenopus tropicalis)
  - GPCR ligand binding (Xenopus tropicalis)
    - Class A/1 (Rhodopsin-like receptors) (Xenopus tropicalis)
      - Peptide ligand-binding receptors (Xenopus tropicalis)
        
        Vasopressin-like receptors (Xenopus tropicalis)
        
        AVPR1A,2 bind AVPR antagonists (Xenopus tropicalis)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]
        
        AVPR1A,2:AVPR antagonists [plasma membrane] (Xenopus tropicalis)
        
        AVPR antagonists [extracellular region]
        
        lixivaptan [extracellular region]

External Reference Information

External Reference

lixivaptan [Guide to Pharmacology:2238]

Participates

as a candidate of

AVPR antagonists [extracellular region]

Disease

Name	Identifier	Synonyms
hyponatremia	DOID:0019146

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