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BIL [nucleoplasm]
Stable Identifier
R-ALL-9709898
Type
Chemical Compound [SimpleEntity]
Compartment
nucleoplasm
Synonyms
bilirubin, bilirubin IXalpha
Locations in the PathwayBrowser
for Species:
Homo sapiens
Bos taurus
Canis familiaris
Danio rerio
Drosophila melanogaster
Gallus gallus
Mus musculus
Rattus norvegicus
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular response to chemical stress (Bos taurus)
Cytoprotection by HMOX1 (Bos taurus)
Fatty acid ligands activate PPARA (Bos taurus)
Coactivators of PPARalpha [nucleoplasm] (Bos taurus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Bos taurus)
Coactivators of PPARalpha [nucleoplasm] (Bos taurus)
BIL [nucleoplasm]
Metabolism (Bos taurus)
Metabolism of lipids (Bos taurus)
Regulation of lipid metabolism by PPARalpha (Bos taurus)
Fatty acid ligands activate PPARA (Bos taurus)
Coactivators of PPARalpha [nucleoplasm] (Bos taurus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Bos taurus)
Coactivators of PPARalpha [nucleoplasm] (Bos taurus)
BIL [nucleoplasm]
Cellular responses to stimuli (Canis familiaris)
Cellular responses to stress (Canis familiaris)
Cellular response to chemical stress (Canis familiaris)
Cytoprotection by HMOX1 (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
BIL [nucleoplasm]
Metabolism (Canis familiaris)
Metabolism of lipids (Canis familiaris)
Regulation of lipid metabolism by PPARalpha (Canis familiaris)
Fatty acid ligands activate PPARA (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
BIL [nucleoplasm]
Cellular responses to stimuli (Danio rerio)
Cellular responses to stress (Danio rerio)
Cellular response to chemical stress (Danio rerio)
Cytoprotection by HMOX1 (Danio rerio)
Fatty acid ligands activate PPARA (Danio rerio)
Coactivators of PPARalpha [nucleoplasm] (Danio rerio)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Danio rerio)
Coactivators of PPARalpha [nucleoplasm] (Danio rerio)
BIL [nucleoplasm]
Metabolism (Danio rerio)
Metabolism of lipids (Danio rerio)
Regulation of lipid metabolism by PPARalpha (Danio rerio)
Fatty acid ligands activate PPARA (Danio rerio)
Coactivators of PPARalpha [nucleoplasm] (Danio rerio)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Danio rerio)
Coactivators of PPARalpha [nucleoplasm] (Danio rerio)
BIL [nucleoplasm]
Cellular responses to stimuli (Drosophila melanogaster)
Cellular responses to stress (Drosophila melanogaster)
Cellular response to chemical stress (Drosophila melanogaster)
Cytoprotection by HMOX1 (Drosophila melanogaster)
Fatty acid ligands activate PPARA (Drosophila melanogaster)
Coactivators of PPARalpha [nucleoplasm] (Drosophila melanogaster)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Drosophila melanogaster)
Coactivators of PPARalpha [nucleoplasm] (Drosophila melanogaster)
BIL [nucleoplasm]
Metabolism (Drosophila melanogaster)
Metabolism of lipids (Drosophila melanogaster)
Regulation of lipid metabolism by PPARalpha (Drosophila melanogaster)
Fatty acid ligands activate PPARA (Drosophila melanogaster)
Coactivators of PPARalpha [nucleoplasm] (Drosophila melanogaster)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Drosophila melanogaster)
Coactivators of PPARalpha [nucleoplasm] (Drosophila melanogaster)
BIL [nucleoplasm]
Cellular responses to stimuli (Gallus gallus)
Cellular responses to stress (Gallus gallus)
Cellular response to chemical stress (Gallus gallus)
Cytoprotection by HMOX1 (Gallus gallus)
Fatty acid ligands activate PPARA (Gallus gallus)
Coactivators of PPARalpha [nucleoplasm] (Gallus gallus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Gallus gallus)
Coactivators of PPARalpha [nucleoplasm] (Gallus gallus)
BIL [nucleoplasm]
Metabolism (Gallus gallus)
Metabolism of lipids (Gallus gallus)
Regulation of lipid metabolism by PPARalpha (Gallus gallus)
Fatty acid ligands activate PPARA (Gallus gallus)
Coactivators of PPARalpha [nucleoplasm] (Gallus gallus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Gallus gallus)
Coactivators of PPARalpha [nucleoplasm] (Gallus gallus)
BIL [nucleoplasm]
Cellular responses to stimuli (Homo sapiens)
Cellular responses to stress (Homo sapiens)
Cellular response to chemical stress (Homo sapiens)
Cytoprotection by HMOX1 (Homo sapiens)
BIL translocates to the nucleus (Homo sapiens)
BIL [nucleoplasm]
Fatty acid ligands activate PPARA (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Heme signaling (Homo sapiens)
Expression of NPAS2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Circadian Clock (Homo sapiens)
BMAL1:CLOCK,NPAS2 activates circadian gene expression (Homo sapiens)
Expression of PPARA (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of NPAS2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
RORA activates gene expression (Homo sapiens)
Expression of CPT1A (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Developmental Biology (Homo sapiens)
Adipogenesis (Homo sapiens)
Transcriptional regulation of white adipocyte differentiation (Homo sapiens)
Expression of ANGPTL4 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Metabolism (Homo sapiens)
Metabolism of lipids (Homo sapiens)
Metabolism of steroids (Homo sapiens)
Regulation of cholesterol biosynthesis by SREBP (SREBF) (Homo sapiens)
Activation of gene expression by SREBF (SREBP) (Homo sapiens)
Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Regulation of lipid metabolism by PPARalpha (Homo sapiens)
Fatty acid ligands activate PPARA (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
PPARA activates gene expression (Homo sapiens)
Expression of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase (HMGCR) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ABCA1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ABCB4 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ACADM (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ACOX1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ACSL1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of AGT (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ALAS1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ANGPTL4 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ANKRD1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of APOA1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of APOA2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of APOA5 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CD36 (platelet glycoprotein IV, FAT) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CPT1A (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CPT2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CYP1A1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CYP4A11 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of CYP7A1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of FABP1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of FADS1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of FATP1 (SLC27A1) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of FHL2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of Farnesyldiphosphate Farnesyltransferase (FDFT1, Squalene Synthase) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of G0S2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of GLIPR1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of GRHL1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of HMGCS2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of Hydroxymethylglutaryl coenzyme A synthase (HMGCS1) (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of ME1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of NPAS2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of PEX11A (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of PLIN2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of PPARA (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of RGL1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of SULT2A1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of TIAM2 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of TNFRSF21 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of TRIB3 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of TXNRD1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Expression of UGT1A9 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Organelle biogenesis and maintenance (Homo sapiens)
Mitochondrial biogenesis (Homo sapiens)
Transcriptional activation of mitochondrial biogenesis (Homo sapiens)
Expression of ALAS1 (Homo sapiens)
PPARA:RXRA Coactivator complex [nucleoplasm] (Homo sapiens)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
BIL [nucleoplasm]
Cellular responses to stimuli (Mus musculus)
Cellular responses to stress (Mus musculus)
Cellular response to chemical stress (Mus musculus)
Cytoprotection by HMOX1 (Mus musculus)
Fatty acid ligands activate PPARA (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
BIL [nucleoplasm]
Metabolism (Mus musculus)
Metabolism of lipids (Mus musculus)
Regulation of lipid metabolism by PPARalpha (Mus musculus)
Fatty acid ligands activate PPARA (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
BIL [nucleoplasm]
Cellular responses to stimuli (Rattus norvegicus)
Cellular responses to stress (Rattus norvegicus)
Cellular response to chemical stress (Rattus norvegicus)
Cytoprotection by HMOX1 (Rattus norvegicus)
Fatty acid ligands activate PPARA (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
BIL [nucleoplasm]
Metabolism (Rattus norvegicus)
Metabolism of lipids (Rattus norvegicus)
Regulation of lipid metabolism by PPARalpha (Rattus norvegicus)
Fatty acid ligands activate PPARA (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
BIL [nucleoplasm]
PPARA:RXRA Coactivator complex [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
BIL [nucleoplasm]
Literature References
PubMed ID
Title
Journal
Year
27232847
In Cellulo Mapping of Subcellular Localized Bilirubin
Rhee, HW
,
Park, JS
,
Nam, E
,
Lim, MH
,
Lee, HK
ACS Chem Biol
2016
External Reference Information
External Reference
bilirubin(2-) [ChEBI:57977]
Participates
as an output of
BIL translocates to the nucleus (Homo sapiens)
as a member of
Coactivators of PPARalpha [nucleoplasm] (Gallus gallus)
Coactivators of PPARalpha [nucleoplasm] (Rattus norvegicus)
Coactivators of PPARalpha [nucleoplasm] (Mus musculus)
Coactivators of PPARalpha [nucleoplasm] (Xenopus tropicalis)
Coactivators of PPARalpha [nucleoplasm] (Danio rerio)
Coactivators of PPARalpha [nucleoplasm] (Canis familiaris)
Coactivators of PPARalpha [nucleoplasm] (Sus scrofa)
Coactivators of PPARalpha [nucleoplasm] (Drosophila melanogaster)
Coactivators of PPARalpha [nucleoplasm] (Bos taurus)
Coactivators of PPARalpha [nucleoplasm] (Homo sapiens)
Other forms of this molecule
BIL [endoplasmic reticulum lumen]
BIL [extracellular region]
BIL [cytosol]
Cross References
COMPOUND
C00486
ZINC
000018007499
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