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PDPK1:PIP3 [plasma membrane]
Stable Identifier
R-BTA-109697
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Hemostasis (Bos taurus)
Platelet activation, signaling and aggregation (Bos taurus)
GPVI-mediated activation cascade (Bos taurus)
PIP3 recruits PDPK1 to the membrane (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Immune System (Bos taurus)
Adaptive Immune System (Bos taurus)
Costimulation by the CD28 family (Bos taurus)
CD28 co-stimulation (Bos taurus)
CD28 dependent PI3K/Akt signaling (Bos taurus)
PIP3 recruits PDPK1 to the membrane (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
PIP3 recruits PDPK1 to the membrane (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PRKCZ autophosphorylates downstream of estrogen stimulation (Bos taurus)
PDPK1:PIP3:p-T410-PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PRKCZ recruits RAS in response to estrogen stimulation (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PRKCZ stimulates RAS nucleotide exchange in response to estrogen (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GDP [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ:p21 RAS:GTP [plasma membrane] (Bos taurus)
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by Insulin receptor (Bos taurus)
Insulin receptor signalling cascade (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
Activation of AKT2 (Bos taurus)
PDPK1 binds PIP3 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1 phosphorylates AKT2 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R) (Bos taurus)
IGF1R signaling cascade (Bos taurus)
IRS-related events triggered by IGF1R (Bos taurus)
IRS-mediated signalling (Bos taurus)
PI3K Cascade (Bos taurus)
Activation of AKT2 (Bos taurus)
PDPK1 binds PIP3 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1 phosphorylates AKT2 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signaling by VEGF (Bos taurus)
VEGFA-VEGFR2 Pathway (Bos taurus)
VEGFR2 mediated vascular permeability (Bos taurus)
PIP3 recruits PDPK1 to the membrane (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
PDPK1 phosphorylates PKN1,2,3 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Bos taurus)
PDPK1:PIP3 [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
PDPK1 [plasma membrane]
(Bos taurus)
PI(3,4,5)P3 [plasma membrane]
Participates
as a component of
PDPK1:PIP3:pS, p-T410 PRKCZ [plasma membrane] (Bos taurus)
PDPK1:PIP3:p-T410-PRKCZ [plasma membrane] (Bos taurus)
RHOA,RHOB,RHOC,RAC1:GTP:PKN1-3:PDPK1:PIP3 [plasma membrane] (Bos taurus)
as an output of
PDPK1 binds PIP3 (Bos taurus)
PDPK1 phosphorylates PKN1,2,3 (Bos taurus)
PIP3 recruits PDPK1 to the membrane (Bos taurus)
as an input of
RHOA,RHOB,RHOC,RAC1:GTP:PKN1,2,3 binds PDPK1:PIP3 (Bos taurus)
Inferred From
PDPK1:PIP3 [plasma membrane]
(Homo sapiens)
PDPK1:PIP3 [plasma membrane]
(Homo sapiens)
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