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About
What is Reactome ?
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Team
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Our Logo
License Agreement
Privacy Notice
Disclaimer
Digital Preservation
Contact us
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phospho-p-T185,Y187-MAPK1 [nucleoplasm]
Stable Identifier
R-BTA-112354
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
P46196
Locations in the PathwayBrowser
Expand all
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
Oncogene Induced Senescence (Bos taurus)
MAPKs phosphorylate ETS1 and ETS2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
MAPK3 (ERK1) and MAPK1 (ERK2) phosphorylate CEBPB (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Developmental Biology (Bos taurus)
Nervous system development (Bos taurus)
Axon guidance (Bos taurus)
NCAM signaling for neurite out-growth (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-17 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Innate Immune System (Bos taurus)
Fc epsilon receptor (FCERI) signaling (Bos taurus)
FCERI mediated MAPK activation (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
MAP kinase activation (Bos taurus)
MAPK targets/ Nuclear events mediated by MAP kinases (Bos taurus)
Activation of the AP-1 family of transcription factors (Bos taurus)
c-FOS activation by phospho ERK1/2 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
MAPK family signaling cascades (Bos taurus)
MAPK1/MAPK3 signaling (Bos taurus)
RAF-independent MAPK1/3 activation (Bos taurus)
Nuclear DUSPs dephosphorylate MAPKs (Bos taurus)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
p-T,Y MAPKs [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Phosphorylated MAPKs translocate into the nucleus (Bos taurus)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
p-T,Y MAPKs [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
RAF/MAP kinase cascade (Bos taurus)
Negative regulation of MAPK pathway (Bos taurus)
Nuclear DUSPs dephosphorylate MAPKs (Bos taurus)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
p-T,Y MAPKs [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Phosphorylated MAPKs translocate into the nucleus (Bos taurus)
p-T,Y MAPK monomers and dimers [nucleoplasm] (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
p-T,Y MAPKs [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Signaling by GPCR (Bos taurus)
GPCR downstream signalling (Bos taurus)
G alpha (q) signalling events (Bos taurus)
Gastrin-CREB signalling pathway via PKC and MAPK (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Extra-nuclear estrogen signaling (Bos taurus)
Estrogen-dependent nuclear events downstream of ESR-membrane signaling (Bos taurus)
p-S10 CDKN1B translocates to the cytosol (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Estrogen-stimulated signaling through PRKCZ (Bos taurus)
ESR1- and PRCKZ-dependent MAPK1 translocation to the nucleus (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by NTRKs (Bos taurus)
Signaling by NTRK1 (TRKA) (Bos taurus)
Nuclear Events (kinase and transcription factor activation) (Bos taurus)
ERK/MAPK targets (Bos taurus)
ERK1/2 phosphorylates MSK1 (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERK1/2/5 activate RSK1/2/3 (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated (Bos taurus)
ERKs are inactivated by dual-specific phosphatases (DUSPs) (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
ERKs are inactivated by protein phosphatase 2A (Bos taurus)
p-MAPK3/MAPK1/MAPK7 dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
Signalling to ERKs (Bos taurus)
Prolonged ERK activation events (Bos taurus)
Frs2-mediated activation (Bos taurus)
p-T,Y MAPK dimers translocate to nucleus (Bos taurus)
p-T,Y MAPK dimers [nucleoplasm] (Bos taurus)
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
phospho-p-T185,Y187-MAPK1 [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:P46196
Reference Genes
BioGPS Gene:327672
ENSEMBL:ENSBTAG00000010312
KEGG Gene (Bos taurus):327672
Monarch:327672
NCBI Gene:327672
Reference Transcript
RefSeq:NM_175793.2
Other Identifiers
GO:0000165
GO:0000166
GO:0003824
GO:0004672
GO:0004674
GO:0004707
GO:0005524
GO:0005634
GO:0005737
GO:0005768
GO:0005769
GO:0005770
GO:0005794
GO:0005813
GO:0005815
GO:0005819
GO:0005856
GO:0005886
GO:0005901
GO:0005925
GO:0006468
GO:0006915
GO:0007010
GO:0007049
GO:0007166
GO:0012501
GO:0016020
GO:0016192
GO:0016301
GO:0016310
GO:0016740
GO:0018105
GO:0018107
GO:0023052
GO:0031410
GO:0031647
GO:0032872
GO:0035556
GO:0036211
GO:0043226
GO:0051493
GO:0070161
GO:0070849
GO:0072584
GO:0072686
GO:0090170
GO:0106310
GO:0140096
GO:2000641
Participates
as a component of
p-Y185,Y187 MAPK1 dimer [nucleoplasm] (Bos taurus)
as a member of
p-T,Y MAPKs [nucleoplasm] (Bos taurus)
Other forms of this molecule
MAPK1 [ficolin-1-rich granule lumen]
MAPK1 [extracellular region]
MAPK1 [azurophil granule lumen]
phospho-p-T185-MAPK1 [cytosol]
MAPK1 [nucleoplasm]
MAPK1 [cytosol]
phospho-p-T185,Y187-MAPK1 [cytosol]
Inferred From
p-T185,Y187-MAPK1 [nucleoplasm]
(Homo sapiens)
Modified Residues
Name
O-phospho-L-threonine at 185 (in Homo sapiens)
Coordinate
185
PsiMod Name
O-phospho-L-threonine [MOD:00047]
PsiMod Definition
A protein modification that effectively converts an L-threonine residue to O-phospho-L-threonine.
Name
O4'-phospho-L-tyrosine at 187 (in Homo sapiens)
Coordinate
187
PsiMod Name
O4'-phospho-L-tyrosine [MOD:00048]
PsiMod Definition
A protein modification that effectively converts an L-tyrosine residue to O4'-phospho-L-tyrosine.
Cross References
RefSeq
NP_786987.1
Ensembl
ENSBTAP00000013623
,
ENSBTAG00000010312
,
ENSBTAT00000013623
VGNC
31212
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