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KMT2D [nucleoplasm]
Stable Identifier
R-BTA-1183219
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
A0A3Q1N7T9
Locations in the PathwayBrowser
Expand all
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
PKMTs methylate histone lysines (Bos taurus)
Core MLL complex, SMYD3, PRDM9 methylate dimethyl-lysine-5 of histone H3 (H3K4) (Bos taurus)
Core MLL complex, SMYD3, PRDM9 [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
SETD3, SETD7 (KMT7), WHSC1L1 (KMT3F), Core MLL complex methylate lysine-5 of histone H3 (H3K4) (Bos taurus)
SETD3, SETD7, WHSC1L1, Core MLL complex [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
WHSC1L1 (KMT3F), Core MLL complex, SMYD3 (KMT3E) methylate methyl-lysine-5 of histone H3 (H3K4) (Bos taurus)
WHSC1L1, Core MLL complex, SMYD3, SETD3 [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
Epigenetic regulation of gene expression (Bos taurus)
Epigenetic regulation by WDR5-containing histone modifying complexes (Bos taurus)
Epigenetic regulation of gene expression by MLL3 and MLL4 complexes (Bos taurus)
PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
MLL4-ASCOM [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Formation of WDR5-containing histone-modifying complexes (Bos taurus)
Formation of the MLL4 complex (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
PAXIP1:PAGR1 complex, NCOA6 and KDM6A bind MLL4 complex (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
MLL4-ASCOM [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional regulation by RUNX1 (Bos taurus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Core MLL complex [nucleoplasm] (Bos taurus)
MLL4 complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Formation of the beta-catenin:TCF transactivating complex (Bos taurus)
Recruitment of SET1 methyltransferase complex (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
KMT2D [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:A0A3Q1N7T9
Reference Genes
ENSEMBL:ENSBTAG00000014429.6
Participates
as an input of
Formation of the MLL4 complex (Bos taurus)
Recruitment of SET1 methyltransferase complex (Bos taurus)
as a component of
MLL4 complex [nucleoplasm] (Bos taurus)
TCF/LEF:CTNNB1:BCL9:PYGO:SET1-like complex [nucleoplasm] (Bos taurus)
Inferred From
KMT2D [nucleoplasm]
(Homo sapiens)
Cross References
VGNC
30693
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