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What is Reactome ?
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Histone H2A.J [nucleoplasm]
Stable Identifier
R-BTA-1214226
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
nucleoplasm
Synonyms
H2AFJ, H2AJ_BOVIN, H2AFJ
Locations in the PathwayBrowser
Expand all
Cell Cycle (Bos taurus)
Cell Cycle, Mitotic (Bos taurus)
M Phase (Bos taurus)
Mitotic Prophase (Bos taurus)
Condensation of Prophase Chromosomes (Bos taurus)
CDK1 phosphorylates PHF8 (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CDK1 phosphorylates condensin II subunit NCAPD3 (Bos taurus)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Condensin II complex binds H4K20me1-containing nucleosomes (Bos taurus)
Condensin II:Nucleosome with H4K20me1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PHF8 demethylates histone H4K20me1 (Bos taurus)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PLK1 binds phosphorylated condensin II complex (Bos taurus)
Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PLK1 hyperphosphorylates Condensin II complex (Bos taurus)
Hyperphosphorylated Condensin II:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T210-PLK1:Phosphorylated Condensin II:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
SETD8 monomethylates histone H4 (Bos taurus)
PHF8:Nucleosome with H3K4me2/3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PHF8:Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2/3:H4K20me1 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromosome Maintenance (Bos taurus)
Nucleosome assembly (Bos taurus)
Deposition of new CENPA-containing nucleosomes at the centromere (Bos taurus)
New CENPA-containing nucleosomes are deposited at the centromere (Bos taurus)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] (Bos taurus)
Centromeric Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RSF complex binds the centromere (Bos taurus)
CCAN:DNA:CASC5:Centromeric nucleosome:RSF complex [nucleoplasm] (Bos taurus)
Centromeric Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CCAN:DNA:CASC5:Mis18 complex:HJURP complex:CENPA nucleosome [nucleoplasm] (Bos taurus)
Centromeric Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Telomere Maintenance (Bos taurus)
Inhibition of DNA recombination at telomere (Bos taurus)
Histone H3.3 deposition at telomere (Bos taurus)
Telomere:Shelterin:Nucleosome (H3F3A):ATRX:DAXX [nucleoplasm] (Bos taurus)
Telomere:Shelterin:Nucleosome (H3F3A) [nucleoplasm] (Bos taurus)
Nucleosome (H3F3A) [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Telomere:Shelterin:Nucleosome:ATRX:DAXX [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Packaging Of Telomere Ends (Bos taurus)
Incorporation Of Extended And Processed Telomere End Into Associated Protein Structure (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Incorporation Of Extended And Processed Telomere End Into Higher Order T-Loop And Associated Protein Structure (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Cellular responses to stimuli (Bos taurus)
Cellular responses to stress (Bos taurus)
Cellular Senescence (Bos taurus)
DNA Damage/Telomere Stress Induced Senescence (Bos taurus)
Telomere shortening during replicative exhaustion (Bos taurus)
Extended And Processed Telomere End and Associated DNA Binding and Packaging Protein Complex Folded Into Higher Order Structure [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Oxidative Stress Induced Senescence (Bos taurus)
KDM6B demethylates H3K27me3 on p16INK4A promoter (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CDKN2A Gene:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC1.4 complex binds H3K27Me3 nucleosomes on CDKN2A promoter (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2-EZH2 trimethylates nucleosomes associated with CDKN2A promoter (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CDKN2A Gene:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-MAPKAPK3 phosphorylates BMI1 (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome:PRC1.4 [nucleoplasm] (Bos taurus)
CDKN2A Gene:H3K27Me3-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Senescence-Associated Secretory Phenotype (SASP) (Bos taurus)
EHMT1:EHMT2 methylates IL6 promoter (Bos taurus)
IL6 gene:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
IL6 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
EHMT1:EHMT2 methylates IL8 promoter (Bos taurus)
IL8 gene:Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
IL8 gene:Nucleosome-H3K9Me2 [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromatin organization (Bos taurus)
Chromatin modifying enzymes (Bos taurus)
RMTs methylate histone arginines (Bos taurus)
PRMT5:pT5-WDR77 methylates arginine-4 of histone H2A (H2AR3) (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
DNA Repair (Bos taurus)
Base Excision Repair (Bos taurus)
Base-Excision Repair, AP Site Formation (Bos taurus)
Depurination (Bos taurus)
Cleavage of the damaged purine (Bos taurus)
NEIL3 cleaves 5-guanidinohydantoin (Gh) from damaged telomeric DNA (Bos taurus)
NEIL3:AP-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
AP-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Recognition and association of DNA glycosylase with site containing an affected purine (Bos taurus)
NEIL3 recognizes and binds to 5-guanidinohydantoin (Gh) in telomeric DNA (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
NEIL3:Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Gh-Telomeric DNA:Shelterin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
DNA Replication (Bos taurus)
DNA Replication Pre-Initiation (Bos taurus)
Assembly of the pre-replicative complex (Bos taurus)
Assembly of the ORC complex at the origin of replication (Bos taurus)
ORC1 binds to H4K20me2 (Bos taurus)
H4K20Me2-nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
ORC1:H4K20Me2-nucleosome [nucleoplasm] (Bos taurus)
H4K20Me2-nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Gene expression (Transcription) (Bos taurus)
Epigenetic regulation of gene expression (Bos taurus)
Negative epigenetic regulation of rRNA expression (Bos taurus)
NoRC negatively regulates rRNA expression (Bos taurus)
MBD2 binds methylcytosine in chromatin (Bos taurus)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Bos taurus)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
SIRT1 negatively regulates rRNA expression (Bos taurus)
Formation of energy-dependent Nucleolar Silencing Complex (eNoSC) (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
eNoSC deacetylates histone H3 (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromatin with acetylated H3 [nucleoplasm] (Bos taurus)
Nucleosome (H3K9ac, H3K14ac) [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
eNoSC dimethylates histone H3 at lysine-9 (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
eNoSC [nucleoplasm] (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2 methylates histones and DNA (Bos taurus)
DNMT1,3A,3B:PRC2 methylates cytosine and histone H3 (Bos taurus)
DNMT1,3A,3B:PRC2:Chromatin (5-mC, H3K27me3) [nucleoplasm] (Bos taurus)
PRC2:Chromatin (5-methylcytosine, H3K27me3) [nucleoplasm] (Bos taurus)
Chromatin with hemimethylC, H3K27me3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Bos taurus)
PRC2 Core:Chromatin [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2 recruits DNA methyltransferases (Bos taurus)
DNMT1,3A,3B:PRC2:Chromatin [nucleoplasm] (Bos taurus)
PRC2 Core:Chromatin [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2 Core:Chromatin [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2 trimethylates histone H3 at lysine-27 (Bos taurus)
PRC2:Chromatin (H3K27me3) [nucleoplasm] (Bos taurus)
Chromatin with trimethylated H3K27 [nucleoplasm] (Bos taurus)
Nucleosome with H3K27me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2:Chromatin [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Polycomb Repressive Complex 2 (PRC2) Is recruited to chromatin (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRC2:Chromatin [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Positive epigenetic regulation of rRNA expression (Bos taurus)
B-WICH complex positively regulates rRNA expression (Bos taurus)
B-WICH:histone acetyltransferase acetylates histone H3 at lysine-9 (Bos taurus)
Nucleosome (H3K9ac) [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Gene Silencing by RNA (Bos taurus)
Transcriptional regulation by small RNAs (Bos taurus)
AGO1,2:small RNA complexes interact with chromatin (Bos taurus)
AGO1,2:miRNA:chromatin:RNA pol II [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Chromatin [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RNA Polymerase I Transcription (Bos taurus)
RNA Polymerase I Promoter Clearance (Bos taurus)
RNA Polymerase I Promoter Escape (Bos taurus)
Elongation of pre-rRNA transcript (Bos taurus)
Chromatin (H3K9me2):CBX3 [nucleoplasm] (Bos taurus)
Chromatin (H3K9me2) [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RNA Polymerase I Promoter Opening (Bos taurus)
UBF-1 Binds rDNA Promoter (Bos taurus)
Chromatin (H3K9me2, 5mC):MBD2 [nucleoplasm] (Bos taurus)
Chromatin with H3K9me2, 5mC [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RNA Polymerase II Transcription (Bos taurus)
Generic Transcription Pathway (Bos taurus)
Transcriptional regulation by RUNX1 (Bos taurus)
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
H3K4me2-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:GP1BA gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
H3K4me2-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:ITGA2B gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
H3K4me2-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:MIR27A gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Core MLL complex methylates H3K4Me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
H3K4me2-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
H3K4me3-Nucleosome:THBS1 gene:RUNX1,MeR206,MeR210-RUNX1:CBFB:PRMT1:GATA1:ZFPM1:Core MLL complex:EP300:KAT2B [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the GP1BA gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:GP1BA gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the ITGA2B gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:ITGA2B gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the MIR27A gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:MIR27A gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PRMT6 arginine methylates H3K4me2-Nucleosome at the THBS1 gene promoter (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1 gene:H3K4me2-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
RUNX1:CBFB:SIN3A,(SIN3B):PRMT6:HDAC1:THBS1B gene:H3K4me2,H3R2me2a-Nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 and H3R2me2a [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Signal Transduction (Bos taurus)
Signaling by Nuclear Receptors (Bos taurus)
ESR-mediated signaling (Bos taurus)
Estrogen-dependent gene expression (Bos taurus)
ESR1:ESTG and KDM4B bind H3K9me3 target gene enhancers (Bos taurus)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Bos taurus)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
FOXA1 and GATA3 bind to CCND1 promoter (Bos taurus)
CCND1 gene:H3K4me2 nucleosome:FOXA1:GATA3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
CCND1 gene:H3K4me2 nucleosome:YY1:HDAC1 [nucleoplasm] (Bos taurus)
Nucleosome with H3K4me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM4B demethylates H3K9me3 on estrogen-responsive target enhancers (Bos taurus)
KDM4B-regulated genes:H3K9me3 nucleosome:ESR1:ESTG:KDM4B [nucleoplasm] (Bos taurus)
KDM4B-regulated genes:H3K9me3 nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM4B-regulated genes:nucleosome:ESR1:ESTG [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
NR5A2, ZNF217 and NCOA3 bind GREB1 promoter (Bos taurus)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
GREB1 gene:nucleosome:ESR1:ESTG:ZNF217:NCOA3:NR5A2 [nucleoplasm] (Bos taurus)
GREB1 gene:nucleosome:ESR1:ESTG [nucleoplasm] (Bos taurus)
Nucleosome [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Overexpressed HIST1H2AC and ESR1:ESTG bind MYC and BCL2 genes (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
MYC gene, BCL2 gene: H3K9me2 nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me2 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Signaling by Rho GTPases, Miro GTPases and RHOBTB3 (Bos taurus)
Signaling by Rho GTPases (Bos taurus)
RHO GTPase Effectors (Bos taurus)
RHO GTPases activate PKNs (Bos taurus)
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3 (Bos taurus)
Demethylase KDM1A binds KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Demethylase KDM4C binds KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM1A demethylates dimethylated H3K9 (Me2K-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,Me2K-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM1A demethylates monomethylated H3K9 (MeK-10-H3) at KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,KLK3 Gene:Nucleosome with p-T12,MeK-10-H3:KDM1A [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,MeK-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, MeK-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
KDM4C demethylates Me3K-10-H3 associated with KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3:KDM4C [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12-Me2K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me2K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PKN1 phosphorylates histone 3 of nucleosomes associate with KLK2 and KLK3 promoters (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with p-T12,Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with p-T12, Me3K-10-H3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
PKN1:AR complex binds promoters of KLK2 and KLK3 genes (Bos taurus)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
p-T774-PKN1:AR:Androgen:KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
KLK2,3 Gene:Nucleosome with Me3K-10-H3 [nucleoplasm] (Bos taurus)
Nucleosome with H3K9me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
Signaling by WNT (Bos taurus)
TCF dependent signaling in response to WNT (Bos taurus)
Formation of the beta-catenin:TCF transactivating complex (Bos taurus)
SET1 complex trimethylates H3K4 at the MYC gene (Bos taurus)
MYC gene: H2B K121ub nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H2BK121ub [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
MYC gene:H2B K121ub H3K4me3 nucleosome [nucleoplasm] (Bos taurus)
Nucleosome with H2BK121ub and H3K4me3 [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Histone H2A.J [nucleoplasm] (Bos taurus)
External Reference Information
External Reference
UniProt:Q3ZBX9 H2AJ
Gene Names
H2AJ
Chain
chain:1-129
Reference Genes
BioGPS Gene:618489 H2AJ
ENSEMBL:ENSBTAG00000030503.3 H2AJ
KEGG Gene (Bos taurus):618489 H2AJ
Monarch:618489 H2AJ
NCBI Gene:618489 H2AJ
Reference Transcript
RefSeq:NM_001078089.2 H2AJ
Other Identifiers
618489
GO:0000786
GO:0003677
GO:0005198
GO:0005694
GO:0030527
GO:0043226
GO:0046982
Participates
as a candidate of
Histone H2A (bovine) [nucleoplasm] (Bos taurus)
Histone H2A [nucleoplasm] (Bos taurus)
Inferred From
H2AFJ [nucleoplasm]
(Homo sapiens)
Cross References
RefSeq
NP_001071557.1
OpenTargets
ENSG00000246705
Ensembl
ENSBTAP00000040641
,
ENSBTAG00000030503
,
ENSBTAT00000043046
VGNC
83623
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