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NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane]
Stable Identifier
R-BTA-1306974
Type
Complex
Species
Bos taurus
Compartment
plasma membrane
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Intracellular signaling by second messengers (Bos taurus)
PIP3 activates AKT signaling (Bos taurus)
Negative regulation of the PI3K/AKT network (Bos taurus)
PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Bos taurus)
PI3K phosphorylates PIP2 to PIP3 (Bos taurus)
Activator:PI3K [plasma membrane] (Bos taurus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Bos taurus)
Signaling by Receptor Tyrosine Kinases (Bos taurus)
Signaling by ERBB2 (Bos taurus)
PI3K events in ERBB2 signaling (Bos taurus)
Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Bos taurus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Bos taurus)
PIP2 to PIP3 conversion by PI3K bound to phosphorylated heterodimer of ERBB2 and ERBB4 CYT1 (Bos taurus)
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Phosphorylated ERBB2:ERBB4cyt1 heterodimers [plasma membrane]
(Bos taurus)
PIK3CA:PIK3R1 [cytosol]
(Bos taurus)
Participates
as an output of
Binding of PI3K to p-ERBB2:p-ERBB4 CYT-1 heterodimers (Bos taurus)
as a member of
Activator:PI3K [plasma membrane] (Bos taurus)
Inferred From
NRGs/EGFLs:p-ERBB4cyt1:p-ERBB2:PI3K [plasma membrane]
(Homo sapiens)
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