Reactome | CLEC6A [plasma membrane]

CLEC6A [plasma membrane]

Stable Identifier

R-BTA-1472857

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

plasma membrane

Synonyms

Q3LUH2

Locations in the PathwayBrowser

Expand all

Immune System (Bos taurus)

- Innate Immune System (Bos taurus)
  - C-type lectin receptors (CLRs) (Bos taurus)
    - Dectin-2 family (Bos taurus)
      - LYN and FYN phosphorylate FCER1G in CLEC6A:FCERG and CLEC4E:FCERG (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
      - PLCG2 translocates from cytosol to plasma membrane (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
      - SYK autophosphorylates (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
      - SYK binds to p-Y65,Y76-FCER1G (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
      - SYK phosphorylates PLCG2 in p-6Y-SYK:p-Y65,Y76-FCER1G:PLCG2 (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:PLCG2 [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK:p-Y753,Y759-PLCG2 [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer:p-6Y-SYK [plasma membrane] (Bos taurus)
        
        pathogens:CLEC6A,CLEC4E:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer:alpha-mannan [plasma membrane] (Bos taurus)
        
        CLEC6A:p-Y65,Y76-FCER1G dimer [plasma membrane] (Bos taurus)
        
        CLEC6A [plasma membrane] (Bos taurus)

External Reference Information

External Reference

UniProt:Q3LUH2

Reference Genes

BioGPS Gene:514979

ENSEMBL:ENSBTAG00000023635

ENSEMBL:ENSBTAG00000023635.5

KEGG Gene (Bos taurus):514979

Monarch:514979

NCBI Gene:514979

Reference Transcript

RefSeq:NM_001034479.1

Other Identifiers

514979

GO:0001819

GO:0002250

GO:0002376

GO:0005509

GO:0005537

GO:0005886

GO:0009897

GO:0016020

GO:0023052

GO:0030246

GO:0038187

GO:0043123

GO:0045087

GO:0046872

GO:0050832

GO:0060089

GO:0061760

GO:0098542

GO:2000318

Participates

as a component of

Other forms of this molecule

CLEC4C [ficolin-1-rich granule membrane]

CLEC4C [secretory granule membrane]

CLEC4C [tertiary granule membrane]

CLEC4C [plasma membrane]

Inferred From

CLEC6A [plasma membrane] (Homo sapiens)

Cross References

RefSeq

NP_001029651.1

Ensembl

ENSBTAP00000032279, ENSBTAG00000023635, ENSBTAT00000032346

VGNC

27436

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