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TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
Stable Identifier
R-BTA-166163
Type
Complex
Species
Bos taurus
Compartment
endosome membrane
Locations in the PathwayBrowser
Expand all
Immune System (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
SARM binds TICAM1:TRAM:TLR4:LY96:LPS:CD14 (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
Activation of IRF3, IRF7 mediated by TBK1, IKKε (IKBKE) (Bos taurus)
Auto-ubiquitination of TRAF3 (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
IKKε (IKBKE) is phosphorylated within the activated TLR4 complex (Bos taurus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
IRF3/IRF7 recruitment to p-TBK1/p-IKK epsilon bound to the activated TLR4 (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Bos taurus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Bos taurus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Phosphorylation of IRF-3/IRF7 and their release from the activated TLR complex (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Bos taurus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE:IRF3/IRF7 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:K63polyUb-TRAF3:K63polyUb-TANK:p-TBK1/p-IKBKE [endosome membrane] (Bos taurus)
p-S172-IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Recruitment of IKKε (IKBKE) to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Bos taurus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Recruitment of TBK1 to K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Regulation of TBK1, IKKε (IKBKE)-mediated activation of IRF3, IRF7 (Bos taurus)
IKKε (IKBKE) is ubiquitinated within the activated TLR4 (Bos taurus)
IKBKE:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-IKBKE:K63polyUb-TANK:K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
OPTN binds TBK1 within the activated TLR4 complex (Bos taurus)
OPTN:TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [plasma membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1 is ubiquitinated within TBK1:K63polyUb-TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Bos taurus)
K63polyUb-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TANK binds K63-poly-Ub-TRAF3:TICAM1:activated TLR4 (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TANK is ubiquitinated within TANK:K63polyUb-TRAF3:TRIF:activated TLR4 (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TANK:K63-poly-Ub-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1 is phosphorylated within the activated TLR4 complex (Bos taurus)
OPTN:TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [plasma membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
p-S172-TBK1:K63polyUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-TANK:K63pUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63polyUb-TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF3 binds TICAM1:activated TLR4 complex (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF3:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
IKK complex recruitment mediated by RIP1 (Bos taurus)
IKBKG subunit of IKK complex binds polyubiquinated RIP1 (Bos taurus)
CHUK:IKBKB:IKBKG:K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
K63-linked ubiquitination of RIP1 bound to the activated TLR complex (Bos taurus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRIF:activated TLR3/TLR4 complex recruits RIP1 (Bos taurus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF6-mediated induction of TAK1 complex within TLR4 complex (Bos taurus)
Activated TLR4:TICAM1 recruits TRAF6 (Bos taurus)
SARM:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Activated TLR4:TICAM1:K63pUb-TRAF6 recruits TAK1complex (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Bos taurus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Activation of TAK1 complex bound to activated TLR4 complex (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:TAK1complex [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Auto ubiquitination of TRAF6 bound to the activated TLR4 complex (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Phosphorylated TAK1 leaves activated TLR receptor complex (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TICAM1:K63pUb-TRAF6:free K63pUb:activated TAK1 complex [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRIF-mediated programmed cell death (Bos taurus)
Caspase-8 processing within TLR4 complex (Bos taurus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
RIP3 binds TRIF to mediate necroptosis (Bos taurus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIP3:RIP1:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
RIP3:TICAM1:activated TLR4 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRIF:activated TLR4 [endosome membrane] (Bos taurus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TLR4-induced ripoptosome assembly (Bos taurus)
K63pUb-RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
RIP1:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Bos taurus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation (Bos taurus)
Activated TRAF6 synthesizes unanchored polyubiquitin chains upon TLR stimulation (Bos taurus)
K63-linked polyUb TRAF6 complexes [endosome membrane] (Bos taurus)
K63-pUb-TRAF6:TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Programmed Cell Death (Bos taurus)
Apoptosis (Bos taurus)
Caspase activation via extrinsic apoptotic signalling pathway (Bos taurus)
Caspase activation via Death Receptors in the presence of ligand (Bos taurus)
Caspase-8 processing within TLR4 complex (Bos taurus)
activated TLR4:TRIF:RIP1:FADD [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
activated TLR4:TRIF:RIP1:FADD:pro-caspase-8 [endosome membrane] (Bos taurus)
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
x 2
phospho-TICAM2 [endosome membrane]
(Bos taurus)
TLR4:LY96:LPS:CD14 [endosome membrane]
(Bos taurus)
Participates
as an output of
TLR4:LY96:LPS:CD14 recruits TRAM (TICAM2) (Bos taurus)
as a component of
TICAM1:TRAM:TLR4:LY96:LPS:CD14 [endosome membrane] (Bos taurus)
Inferred From
TRAM:TLR4:LY96:LPS:CD14 [endosome membrane]
(Homo sapiens)
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