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SEL1L [endoplasmic reticulum membrane]
Stable Identifier
R-BTA-1911545
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
endoplasmic reticulum membrane
Synonyms
SEL1L, F1MGJ5
Locations in the PathwayBrowser
Expand all
Signal Transduction (Bos taurus)
Signaling by Hedgehog (Bos taurus)
Hedgehog ligand biogenesis (Bos taurus)
C-terminal Hh fragments are recruited to SEL1:SYVN1 at the ER membrane (Bos taurus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
SYVN1 ubiquitinates Hh C-terminal fragments (Bos taurus)
C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
VCP-catalyzed ATP hydrolysis promotes the translocation of Hh-C into the cytosol (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
ub-C-terminal Hh fragments:ERLEC/OS9:SEL1:SYVN1dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
Transport of small molecules (Bos taurus)
ABC-family proteins mediated transport (Bos taurus)
CFTR binds components of the ERAD machinery for ubiquitination and degradation (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
RNF5 and RNF185 ubiquitinate misfolded CFTR (Bos taurus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
misfolded CFTR:ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
VCP-catalyzed ATP hydrolysis promotes the translocation of misfolded CFTR into the cytosol (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
Ub-misfolded nascent CFTR:ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
SEL1L [endoplasmic reticulum membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:F1MGJ5
Gene Names
SEL1L
Reference Genes
ENSEMBL:ENSBTAG00000008083.6
Other Identifiers
614959
GO:0000839
GO:0005783
GO:0005789
GO:0006886
GO:0016020
GO:0030163
GO:0030970
GO:0036503
GO:0036513
GO:0043226
Participates
as a component of
SEL1:SYVN1 dimer:DERL2:VCP hexamer [endoplasmic reticulum membrane] (Bos taurus)
ERAD complex [endoplasmic reticulum membrane] (Bos taurus)
Inferred From
SEL1L [endoplasmic reticulum membrane]
(Homo sapiens)
Cross References
OpenTargets
ENSG00000071537
Ensembl
ENSBTAG00000008083
,
ENSBTAT00000010628
,
ENSBTAP00000010628
VGNC
49962
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