CYP11B1 oxidises 11DCORT

Stable Identifier
R-BTA-193997
Type
Reaction [transition]
Species
Bos taurus
Compartment
Synonyms
11-deoxycortisol is oxidised to cortisol by CYP11B1, 11-deoxycortisol + NADPH + H+ + O2 => cortisol + NADP+ + H2O
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This event has been computationally inferred from an event that has been demonstrated in another species.

The inference is based on the homology mapping from PANTHER. Briefly, reactions for which all involved PhysicalEntities (in input, output and catalyst) have a mapped orthologue/paralogue (for complexes at least 75% of components must have a mapping) are inferred to the other species. High level events are also inferred for these events to allow for easier navigation.

More details and caveats of the event inference in Reactome. For details on PANTHER see also: http://www.pantherdb.org/about.jsp

Participants
Participates
Catalyst Activity

steroid 11-beta-monooxygenase activity of Cytochrome P450 (CYP11B1 based) [mitochondrial inner membrane]

This event is regulated
Positively by
Inferred From
Created
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