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UBE2N:UBE2V1 [cytosol]
Stable Identifier
R-BTA-202463
Type
Complex
Species
Bos taurus
Compartment
cytosol
Locations in the PathwayBrowser
Expand all
Autophagy (Bos taurus)
Macroautophagy (Bos taurus)
Selective autophagy (Bos taurus)
Aggrephagy (Bos taurus)
Misfolded proteins bind PRKN:UBE2N:UBE2V1:Ub (Bos taurus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Parkin transfers Ub to misfolded proteins (Bos taurus)
Misfolded proteins:PRKN:UBE2N:UBE2V1:Ub [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Ub:misfolded proteins polymerize to PolyUb:misfolded proteins (Bos taurus)
PolyUb:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Ub:Misfolded proteins:PRKN:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Immune System (Bos taurus)
Cytokine Signaling in Immune system (Bos taurus)
Signaling by Interleukins (Bos taurus)
Interleukin-1 family signaling (Bos taurus)
Interleukin-1 signaling (Bos taurus)
Pellino ubiquitinates IRAK1 (Bos taurus)
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
TAK1 is activated within the TAK1 complex (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
TRAF6 is K63 poly-ubiquitinated (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Interleukin-17 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Innate Immune System (Bos taurus)
Toll-like Receptor Cascades (Bos taurus)
Toll Like Receptor 10 (TLR10) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 2 (TLR2) Cascade (Bos taurus)
Toll Like Receptor TLR1:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor TLR6:TLR2 Cascade (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 3 (TLR3) Cascade (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 4 (TLR4) Cascade (Bos taurus)
MyD88-independent TLR4 cascade (Bos taurus)
TRIF (TICAM1)-mediated TLR4 signaling (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
MyD88:MAL(TIRAP) cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 5 (TLR5) Cascade (Bos taurus)
MyD88 cascade initiated on plasma membrane (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 7/8 (TLR7/8) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
Toll Like Receptor 9 (TLR9) Cascade (Bos taurus)
MyD88 dependent cascade initiated on endosome (Bos taurus)
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation (Bos taurus)
MAP kinase activation (Bos taurus)
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1 (Bos taurus)
Activated TAK1 phosphorylates MKK4/MKK7 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
activated TAK1 mediates p38 MAPK activation (Bos taurus)
activated human TAK1 phosphorylates MKK3/MKK6 (Bos taurus)
Activated TAK complexes [cytosol] (Bos taurus)
hp-IRAK1:K63polyUboligo-TRAF6:Activated TAK1 complex [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1 [cytosol] (Bos taurus)
General
This complex/polymer has been computationally inferred (based on PANTHER) from a complex/polymer involved in an event that has been demonstrated in another species.
Participants
components
Ghost homologue of UBE2V1 [cytosol]
(Bos taurus)
UBE2N [cytosol]
(Bos taurus)
Participates
as a component of
K63polyUb-hp-IRAK1:p-Pellino-1,2,(3):UBE2N:UBE2V1 [cytosol] (Bos taurus)
hp-IRAK1:3xK63-polyUb-TRAF6:3xUBE2N:UBE2V1 [cytosol] (Bos taurus)
Ub:UBE2N:UBE2V1 [cytosol] (Bos taurus)
UBE2N:UBE2V1:PRKN [cytosol] (Bos taurus)
Inferred From
UBE2N:UBE2V1 [cytosol]
(Homo sapiens)
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