Reactome | GRB7 [cytosol]

GRB7 [cytosol]

Stable Identifier

R-BTA-204819

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

GRB7, Q1RMW5

Locations in the PathwayBrowser

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External Reference Information

External Reference

UniProt:Q1RMW5

Gene Names

GRB7

Reference Genes

BioGPS Gene:508847 GRB7

ENSEMBL:ENSBTAG00000017366

ENSEMBL:ENSBTAG00000017366.4 GRB7

KEGG Gene (Bos taurus):508847 GRB7

Monarch:508847 GRB7

NCBI Gene:508847 GRB7

Reference Transcript

RefSeq:NM_001046014.1 GRB7
RefSeq:XM_005220695.3 GRB7
RefSeq:XM_015458827.1 GRB7
RefSeq:XM_005220697.2 GRB7
RefSeq:XM_005220694.3 GRB7
RefSeq:XM_005220696.3 GRB7

Other Identifiers

508847

GO:0007165

GO:0023052

Participates

as a member of

RND1 effectors [cytosol] (Bos taurus)
GRB7,GRB10 [cytosol] (Bos taurus)
Adapter proteins [cytosol] (Bos taurus)

as an input of

Grb7 binds to the active PDGF receptor (Bos taurus)
Interaction of Tie2 and Grb7 (Bos taurus)
GRB7 binds phosphorylated heterodimer of ERBB2 and ERBB3 (Bos taurus)

as a component of

PDGF:Phospho-PDGF receptor dimer:Grb7 [plasma membrane] (Bos taurus)
Tie2:Grb7 complex [plasma membrane] (Bos taurus)
NRG1/2:p-10Y-ERBB3:p-ERBB2:GRB7 [plasma membrane] (Bos taurus)

Inferred From

GRB7 [cytosol] (Homo sapiens)

Cross References

RefSeq

XP_005220751.1, XP_005220752.1, XP_005220753.1, XP_005220754.1, XP_015314313.1, NP_001039479.1

OpenTargets

ENSG00000141738

Ensembl

ENSBTAT00000023091, ENSBTAG00000017366, ENSBTAP00000023091

VGNC

29632