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GPC3 [plasma membrane]
Stable Identifier
R-BTA-2076656
Type
Protein [EntityWithAccessionedSequence]
Species
Bos taurus
Compartment
plasma membrane
Synonyms
HS(6)-GPC3, Q3ZBZ6
Locations in the PathwayBrowser
Expand all
Metabolism (Bos taurus)
Metabolism of carbohydrates (Bos taurus)
Glycosaminoglycan metabolism (Bos taurus)
Heparan sulfate/heparin (HS-GAG) metabolism (Bos taurus)
HS-GAG biosynthesis (Bos taurus)
Some HSPGs are secreted to the plasma membrane (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
HS-GAG degradation (Bos taurus)
HS-GAGs translocate to the lysosome for degradation (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
Heparanase 2 (HPSE2) binds heparan sulfate proteoglycans (Bos taurus)
HPSE2:HS/HPIN-PGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
Metabolism of vitamins and cofactors (Bos taurus)
Metabolism of fat-soluble vitamins (Bos taurus)
Retinoid metabolism and transport (Bos taurus)
CR:atREs binds apoE and HSPG (Bos taurus)
CR:atREs:HSPG:apoE [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Bos taurus)
CR:atREs:HSPG:apoE [early endosome] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
CR:atREs:HSPG:apoE [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
Sensory Perception (Bos taurus)
Visual phototransduction (Bos taurus)
Retinoid metabolism and transport (Bos taurus)
CR:atREs binds apoE and HSPG (Bos taurus)
CR:atREs:HSPG:apoE [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
LRPs transport extracellular CR:atREs:HSPG:apoE to cytosol (Bos taurus)
CR:atREs:HSPG:apoE [early endosome] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
CR:atREs:HSPG:apoE [plasma membrane] (Bos taurus)
HSPGs [plasma membrane] (Bos taurus)
HS/HPIN-PGs [plasma membrane] (Bos taurus)
GPC3 [plasma membrane] (Bos taurus)
External Reference Information
External Reference
UniProt:Q3ZBZ6
Gene Names
GPC3
Reference Genes
BioGPS Gene:615239 GPC3
ENSEMBL:ENSBTAG00000020406.6
KEGG Gene (Bos taurus):615239 GPC3
Monarch:615239 GPC3
NCBI Gene:615239 GPC3
Reference Transcript
RefSeq:NM_001035463.2 GPC3
Other Identifiers
GO:0005886
GO:0009966
GO:0009986
GO:0016020
GO:0016477
GO:0023052
GO:0030312
GO:0031012
GO:0048870
GO:0062023
GO:0090263
GO:0098552
GO:1905475
Participates
as a member of
HS/HPIN-PGs [plasma membrane] (Bos taurus)
Other forms of this molecule
GPC3 [lysosomal lumen]
GPC3 [lysosomal lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [plasma membrane]
GPC3 [plasma membrane]
GPC3 [plasma membrane]
GPC3 [plasma membrane]
GPC3 [plasma membrane]
GPC3 [endoplasmic reticulum lumen]
phospho-GPC3 [endoplasmic reticulum lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
GPC3 [Golgi lumen]
Inferred From
HS(6)-GPC3 [plasma membrane]
(Homo sapiens)
Modified Residues
Name
O-xylosyl-L-serine (ChEBI:63666) at unknown position
Modification
beta-D-IdoA-(1->4)-alpha-D-GlcNS6S-(1->4)-beta-D-IdoA2S-(1->4)-alpha-D-GlcNS3S-(1->4)-beta-D-GlcA-(1->3)-beta-D-Gal-(1->3)-beta-D-Gal-(1->4)-beta-D-Xyl-yl group
PsiMod Name
O-xylosyl-L-serine
PsiMod Definition
A protein modification that effectively converts an L-serine residue to O3-xylosylserine.
Cross References
RefSeq
NP_001030540.1
OpenTargets
ENSG00000147257
Ensembl
ENSBTAG00000020406
,
ENSBTAT00000027192
,
ENSBTAP00000027192
VGNC
29525
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