Reactome | PRKCZ [cell junction]

PRKCZ [cell junction]

Stable Identifier

R-BTA-2134483

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cell junction

Synonyms

PRKCZ, A0JNH7

Locations in the PathwayBrowser

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Signal Transduction (Bos taurus)

- Signaling by TGFB family members (Bos taurus)
  - Signaling by TGF-beta Receptor Complex (Bos taurus)
    - TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition) (Bos taurus)
      - Disassembly of tight junctions (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)
        
        PRKCZ [cell junction] (Bos taurus)
      - SMURF1 binds phosphorylated PARD6A (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)
        
        PRKCZ [cell junction] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)
        
        PRKCZ [cell junction] (Bos taurus)
      - SMURF1 ubiquitinates RHOA (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)
        
        PRKCZ [cell junction] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:Ub-RHOA:SMURF1 [cell junction] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA:SMURF1 [plasma membrane] (Bos taurus)
        
        Tight Junction Complex:TGFB1:TGFBR2:p-TGFBR1:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        Tight Junction Complex:p-PARD6A:RHOA [cell junction] (Bos taurus)
        
        PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)
        
        PRKCZ [cell junction] (Bos taurus)

External Reference Information

External Reference

UniProt:A0JNH7

Gene Names

PRKCZ

Reference Genes

BioGPS Gene:286877 PRKCZ

ENSEMBL:ENSBTAG00000014119.6

KEGG:bta:286877 PRKCZ

Monarch:286877 PRKCZ

NCBI Gene:286877 PRKCZ

UCSC:A0JNH7 PRKCZ

Reference Transcript

RefSeq:NM_001077833.2 PRKCZ

Other Identifiers

286877

Bt.15734.1.S1_at

GO:0000166

GO:0003824

GO:0004672

GO:0004674

GO:0004697

GO:0005515

GO:0005524

GO:0006468

GO:0008270

GO:0016301

GO:0016740

GO:0046872

GO:0106310

GO:0140096

Participates

as a component of

PARD3:p-PARD6A:PRKCZ [cell junction] (Bos taurus)

Other forms of this molecule

phospho-PRKCZ [cytosol]

PRKCZ [cytosol]

phospho-PRKCZ [cytosol]

Inferred From

PRKCZ [cell junction] (Homo sapiens)

Cross References

RefSeq

NP_001071301.1

ENSEMBL

ENSBTAT00000070692, ENSBTAP00000057570, ENSBTAG00000014119

VGNC

33336

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