Reactome | UBB [cytosol]

UBB [cytosol]

Stable Identifier

R-BTA-3095929

Type

Protein [EntityWithAccessionedSequence]

Species

Bos taurus

Compartment

cytosol

Synonyms

Ub-11-UBB(1-76), P0CG53

Locations in the PathwayBrowser

Expand all

Signal Transduction (Bos taurus)

- MAPK family signaling cascades (Bos taurus)
  - MAPK1/MAPK3 signaling (Bos taurus)
    - RAF/MAP kinase cascade (Bos taurus)
      - RAS processing (Bos taurus)
        
        USP17L2 deubiquitinates RCE1 (Bos taurus)
        
        PolyUb [cytosol] (Bos taurus)
        
        K11polyUb [cytosol] (Bos taurus)
        
        K11-Ub [cytosol] (Bos taurus)
        
        UBB [cytosol] (Bos taurus)

External Reference Information

External Reference

UniProt:P0CG53

Gene Names

UBB

Reference Genes

BioGPS Gene:281370 UBB

ENSEMBL:ENSBTAG00000017246

ENSEMBL:ENSBTAG00000017246.5 UBB

KEGG Gene (Bos taurus):281370 UBB

Monarch:281370 UBB

NCBI Gene:281370 UBB

Reference Transcript

RefSeq:NM_174133.2 UBB

Other Identifiers

281370

GO:0005515

Participates

as a member of

K11-Ub [cytosol] (Bos taurus)

Other forms of this molecule

UBB [endocytic vesicle membrane]

UBB [mitochondrial outer membrane]

UBB [cytosol]

phospho-UBB [nucleoplasm]

UBB [cytosol]

phospho-UBB [cytosol]

UBB [endosome membrane]

UBB [cytosol]

UBB [nucleoplasm]

UBB [cytosol]

UBB [nucleoplasm]

UBB [cytosol]

Inferred From

Ub-11-UBB(1-76) [cytosol] (Homo sapiens)

Modified Residues

Name

ubiquitinylated lysine at 11 (in Homo sapiens)

Coordinate

PsiMod Name

ubiquitinylated lysine [MOD:01148]

PsiMod Definition

A protein modification that effectively crosslinks the N6-amino of a peptidyl lysine with the carboxyl-terminal glycine of a ubiquitin.

Cross References

RefSeq

NP_776558.1

OpenTargets

ENSG00000170315

Ensembl

ENSBTAP00000022919, ENSBTAG00000017246, ENSBTAT00000022919

VGNC

107281

PDB

5TR4

Interactors (1)

Accession	#Entities	Entities	Confidence Score	Evidence (IntAct)
UniProt:O60784 TOM1	3	TOM1 [azurophil granule membrane] (R-HSA-6799348) TOM1 [plasma membrane] (R-HSA-6806274) TOM1 [specific granule membrane] (R-HSA-6800923)	0.743	6

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